675 results on '"Sibley, David R."'
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2. Dopamine receptor divergence revealed using a common ligand
3. Target deconvolution studies of (2R,6R)-hydroxynorketamine: an elusive search
4. High-potency ligands for DREADD imaging and activation in rodents and monkeys.
5. Dual pancreatic adrenergic and dopaminergic signaling as a therapeutic target of bromocriptine
6. Characterization of the Binding Pocket for a Novel Positive Allosteric Modulator of the D1 Dopamine Receptor
7. Discovery, Characterization, and Optimization of a Novel Positive Allosteric Modulator-Antagonist of the D3 Dopamine Receptor
8. Enhancing Ligand Pharmacokinetics While Retaining Dopamine D4 Receptor Potency and Selectivity via Bioisosteric Substitution of Amide Linkers with 1,2,3-Triazoles
9. Regulation of Dopamine Receptor Subtypes by G Protein-Coupled Receptor Kinase Isoforms
10. Time will tell. Reply to “Comments to pharmacological and behavioral divergence of ketamine enantiomers by Jordi Bonaventura et al.” by Chen et al.
11. Pharmacological and behavioral divergence of ketamine enantiomers: implications for abuse liability
12. Dopamine D5 receptor-mediated decreases in mitochondrial reactive oxygen species production are cAMP and autophagy dependent
13. Novel Cryo-EM structures of the D1 dopamine receptor unlock its therapeutic potential
14. New roles for dopamine D2 and D3 receptors in pancreatic beta cell insulin secretion
15. Dopamine regulates pancreatic glucagon and insulin secretion via adrenergic and dopaminergic receptors
16. G Protein-Coupled Receptor Kinase 2 Selectively Enhances β-Arrestin Recruitment to the D2 Dopamine Receptor through Mechanisms That Are Independent of Receptor Phosphorylation
17. Pharmacology and Therapeutic Potential of Benzothiazole Analogues for Cocaine Use Disorder
18. Dissociable control of motivation and reinforcement by distinct ventral striatal dopamine receptors
19. Publisher Correction: The Dopamine D5 receptor contributes to activation of cholinergic interneurons during L-DOPA induced dyskinesia
20. The Dopamine D5 receptor contributes to activation of cholinergic interneurons during L-DOPA induced dyskinesia
21. Identification of Small Molecule Therapeutics and Neuroprotective Gene Targets via High Throughput Screening and RNA Interference inC. elegansParkinson’s Disease Models
22. Delineation of the G Protein-Coupled Receptor Kinase Phosphorylation Sites Within the D1 Dopamine Receptor and Their Role in Regulating Receptor Function
23. Optimization of a Novel D2 Dopamine Receptor-Selective Antagonist into Lead Candidates for the Treatment of Neuropsychiatric Disorders
24. Bioisosteric Replacement of Amides Linkers with 1, 2, 3-Triazoles for Improved Pharmacokinetics Without Losing Dopamine D4 Receptor Potency or Selectivity
25. GRK2 Enhances ß-arrestin Recruitment to the D2 Dopamine Receptor Through a Mechanism that is Independent From Receptor Phosphorylation or G Protein Activation
26. Structure–Activity Relationships of a Brain-Penetrant D3 Dopamine Receptor Negative Allosteric Modulator and Investigation of its Binding Site
27. Dopamine receptors in GtoPdb v.2023.1
28. Delineation of G Protein-Coupled Receptor Kinase Phosphorylation Sites within the D1 Dopamine Receptor and Their Roles in Modulating β-Arrestin Binding and Activation
29. A Targeted Mutation of the D3 Dopamine Receptor Gene is Associated with Hyperactivity in Mice
30. G Protein-Coupled Receptor Kinase 2 Selectively Enhances β-Arrestin Recruitment to the D 2 Dopamine Receptor through Mechanisms That Are Independent of Receptor Phosphorylation.
31. Investigation of the binding and functional properties of extended length D3 dopamine receptor-selective antagonists
32. Identification and Characterization of ML321: A Novel and Highly Selective D2 Dopamine Receptor Antagonist with Efficacy in Animal Models That Predict Atypical Antipsychotic Activity
33. A new era of rationally designed antipsychotics
34. Identification and Characterization of ML321: a Novel and Highly Selective D2Dopamine Receptor Antagonist with Efficacy in Animal Models that Predict Atypical Antipsychotic Activity
35. Dopamine Receptor-Interacting Proteins
36. Pharmacology and Therapeutic Potential of Dopamine D4 Receptor Antagonists for Cocaine Use Disorder
37. The show must go on. Reply to “Distinct functions of S-ketamine and R-ketamine in mediating biobehavioral processes of drug dependency: comments on Bonaventura et al” by Insop Shim
38. 1472-P: Dual Pancreatic Adrenergic and Dopaminergic Signaling as a Therapeutic Mechanism for Treatment of Dysglycemia by Bromocriptine
39. Structural Insights Into D1 Dopamine Receptor Phosphorylation and Desensitization
40. Delineation of G Protein-Coupled Receptor Kinase Phosphorylation Sites within the D 1 Dopamine Receptor and Their Roles in Modulating β-Arrestin Binding and Activation.
41. (-)-Stepholidine is a potent pan-dopamine receptor antagonist of both G protein- and β-arrestin-mediated signaling
42. Establishing an RNA interference (RNAi) screen for neuroprotection of dopaminergic neurons in Caenorhabditis elegans models of Parkinson’s disease
43. Pharmacological actions of a novel and highly selective D3 dopamine receptor agonist, ML417, in a rodent model of Parkinson’s disease
44. Structure–Activity Relationships of a Negative Allosteric Modulator of the D3 Dopamine Receptor and Investigation of its Binding Site
45. Characterization and Chemical Optimization of the D2 Dopamine Receptor‐Selective Antagonist, ML321, Identifies Lead Compounds for the Clinical Treatment of Neuropsychiatric Disorders
46. Novel Dopamine D4 Receptor‐Selective Antagonists For Neuropsychiatric Disorders
47. Regulation of Dopamine Receptor Function and Expression
48. D2 dopamine receptor internalization prolongs the decrease of radioligand binding after amphetamine: A PET study in a receptor internalization-deficient mouse model
49. Development of pyrimidone D1 dopamine receptor positive allosteric modulators
50. D$_1$ and D$_2$ Dopamine Receptor-Regulated Gene Expression of Striatonigral and Striatopallidal Neurons
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