146 results on '"Sibanda E"'
Search Results
2. Assessing the challenges faced by health systems in providing paediatric cotrimoxazole prophylaxis in resource limited countries
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Sibanda, E. L.
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610 - Abstract
Introduction: Cotrimoxazole prophylaxis (CTX-p) is a cost-effective intervention that saves lives of HIV positive individuals. It is recommended by WHO for all infants born to HIV positive women (HIV-exposed infants). Despite this it is poorly implemented in resource limited countries including Zimbabwe. This project aimed to explore health system and patient-level factors that affect implementation of CTX-p among HIV-exposed infants in Harare, Zimbabwe. Methods: In the first phase of the study, policy and implementation procedures for CTX-p were studied at national and health care centre level through document review and key informant interviews. In the second phase, a detailed study of implementation procedures was conducted at Mbare Clinic, Harare, to explore challenges to CTX-p at various points in the prevention of mother to child transmission (PMTCT) cascade. This involved 1) a survey among post-partum women, 2) qualitative interviews with women who delayed/did not seek antenatal care (ANC), 3) follow-up of HIV positive women at six-weeks postpartum to investigate initiation of CTX-p, and 3) follow-up of HIV-exposed infants until six months to explore adherence. In addition, a systematic review was conducted to investigate the magnitude of loss to follow-up (LTFU) of HIV exposed infants from real-life PMTCT programs. Results: CTX-p is recognised as important by the Zimbabwe Ministry of Health; it has been incorporated into guidelines and treatment procedures for HIV-exposed infants. Health systems face challenges implementing CTX-p due to lack of human resources and poor supply chain management. For women, the first hurdle is seeking ANC, where user fees, fear of HIV testing, unsupportive husbands/partners, nurses’ discourteousness and long queues are barriers. Lack of knowledge of the importance of a six-week visit is the main barrier to sixweek visit attendance. Adherence challenges include: unsupportive husbands/partners, drug stock-outs and fear of unwanted HIV disclosure and associated stigma. The systematic review revealed that there is unacceptable LTFU of HIV-exposed infants along various points of the PMTCT cascade. Conclusion: Health care systems need to put in place measures to ensure optimum implementation of life-saving interventions and retention of HIV-exposed infants in care.
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- 2014
3. Process evaluation of an intervention to improve HIV treatment outcomes among children and adolescents
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Seguin, M., primary, Dringus, S., additional, Chiomvu, S., additional, Apollo, T., additional, Sibanda, E., additional, Simms, V., additional, Bernays, S., additional, Chikodzore, R., additional, Redzo, N., additional, Mlilo, P., additional, Ndlovu, L., additional, Nzombe, P., additional, Ncube, B., additional, Kranzer, K., additional, Abbas Ferrand, R., additional, and Chikwari, C. D., additional
- Published
- 2022
- Full Text
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4. Emotional Intelligence and Leadership Abilities
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Herbst, H. H., Maree, J. G., and Sibanda, E.
- Abstract
While exceptional leaders share certain qualities like a strong personal ethic and a compelling vision of the future, research has failed to provide conclusive "proof" of the link between a leader's effectiveness and his/ her emotional intelligence (defined from a cognitive perspective, as a set of abilities). Given the increased recognition of the importance of the role of emotions in the leadership literature, the question arises whether the concept of emotional intelligence has significance for leadership effectiveness. In a pioneering study in the South African context, we examined the possible relationship between four possible facets of emotional intelligence (defined as a multi-faceted ability) and five possible practices of exemplary leaders in the context of leadership in a Higher Education Institution. The sample comprised 138 managers within a Higher Education Institution. The findings provide some evidence that support a positive correlation between emotional intelligence and leadership effectiveness. (Contains 4 tables and 1 figure.)
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- 2006
5. Additional file 2 of Challenges in the diagnosis of asthma in children, what are the solutions? A scoping review of 3 countries in sub Saharan Africa
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Magwenzi, P., Rusakaniko, S., Sibanda, E. N., and Gumbo, F. Z.
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Additional file 2. Data extraction form.
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- 2022
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6. Additional file 1 of Challenges in the diagnosis of asthma in children, what are the solutions? A scoping review of 3 countries in sub Saharan Africa
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Magwenzi, P., Rusakaniko, S., Sibanda, E. N., and Gumbo, F. Z.
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Additional file 1. PRISMA 2020 checklist.
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- 2022
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7. Additional file 3 of Challenges in the diagnosis of asthma in children, what are the solutions? A scoping review of 3 countries in sub Saharan Africa
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Magwenzi, P., Rusakaniko, S., Sibanda, E. N., and Gumbo, F. Z.
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Additional file 3. PRISMA 2020 flow diagram for new systematic reviews which included searches of databases and registers only.
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- 2022
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8. Structural and magnetic properties of DyCrO3
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Sibanda, E. T., primary, Prinsloo, A. R. E., additional, Sheppard, C. J., additional, and Mohanty, P., additional
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- 2022
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9. Natural clinical tolerance to peanut in African patients is caused by poor allergenic activity of peanut IgE
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Wollmann, E., Hamsten, C., Sibanda, E., Ochome, M., Focke-Tejkl, M., Asarnoj, A., Önell, A., Lilja, G., Gallerano, D., Lupinek, C., Thalhamer, T., Weiss, R., Thalhamer, J., Wickman, M., Valenta, R., and van Hage, M.
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- 2015
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10. Toward personalization of asthma treatment according to trigger factors
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Niespodziana, K. Borochova, K. Pazderova, P. Schlederer, T. Astafyeva, N. Baranovskaya, T. Barbouche, M.-R. Beltyukov, E. Berger, A. Borzova, E. Bousquet, J. Bumbacea, R.S. Bychkovskaya, S. Caraballo, L. Chung, K.F. Custovic, A. Docena, G. Eiwegger, T. Evsegneeva, I. Emelyanov, A. Errhalt, P. Fassakhov, R. Fayzullina, R. Fedenko, E. Fomina, D. Gao, Z. Giavina-Bianchi, P. Gotua, M. Greber-Platzer, S. Hedlin, G. Ilina, N. Ispayeva, Z. Idzko, M. Johnston, S.L. Kalayci, Ö. Karaulov, A. Karsonova, A. Khaitov, M. Kovzel, E. Kowalski, M.L. Kudlay, D. Levin, M. Makarova, S. Matricardi, P.M. Nadeau, K.C. Namazova-Baranova, L. Naumova, O. Nazarenko, O. O'Byrne, P.M. Osier, F. Pampura, A.N. Panaitescu, C. Papadopoulos, N.G. Park, H.-S. Pawankar, R. Pohl, W. Renz, H. Riabova, K. Sampath, V. Sekerel, B.E. Sibanda, E. Siroux, V. Sizyakina, L.P. Sun, J.-L. Szepfalusi, Z. Umanets, T. Van Bever, H.P.S. van Hage, M. Vasileva, M. von Mutius, E. Wang, J.-Y. Wong, G.W.K. Zaikov, S. Zidarn, M. Valenta, R.
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immune system diseases ,respiratory tract diseases - Abstract
Asthma is a severe and chronic disabling disease affecting more than 300 million people worldwide. Although in the past few drugs for the treatment of asthma were available, new treatment options are currently emerging, which appear to be highly effective in certain subgroups of patients. Accordingly, there is a need for biomarkers that allow selection of patients for refined and personalized treatment strategies. Recently, serological chip tests based on microarrayed allergen molecules and peptides derived from the most common rhinovirus strains have been developed, which may discriminate 2 of the most common forms of asthma, that is, allergen- and virus-triggered asthma. In this perspective, we argue that classification of patients with asthma according to these common trigger factors may open new possibilities for personalized management of asthma. © 2020 The Authors
- Published
- 2020
11. Contraception Insurance Coverage and Receipt of Long-Acting Reversible Contraception or Depot Medroxyprogesterone Acetate on the Day of Abortion
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Giordana Campos Braga, Obare F, Mbacké C, John F. Stewart, Ilene S. Speizer, Rick O'Hara, Gretchen S. Stuart, Bankole A, Emina Jb, Mweemba O, Jennifer Winston, David K. Guilkey, Dixey R, Rui Alberto Ferriani, Titus Mj, Ojogun Ot, Samantha Charm, Silvana Maria Quintana, Singh S, Atagame Kl, Essete Kebede, Maggwa N, Mberu Bu, Spector H, de Melo Pereira Carmo Ls, Aimee Benson, Iyiwose P, Joanne M. Garrett, Carolina Sales Vieira, Jessica E. Morse, Beguy D, Askew I, Meghan Corroon, Peter Lance, Sibanda E, Alan White, Amy G. Bryant, Darroch Je, Jamie W. Krashin, Ezeh Ac, and Lisa M. Calhoun
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Adult ,medicine.medical_specialty ,media_common.quotation_subject ,medicine.medical_treatment ,Population ,Medroxyprogesterone Acetate ,Abortion ,Insurance Coverage ,Birth rate ,Birth control ,Cohort Studies ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,Pregnancy ,Surveys and Questionnaires ,Environmental health ,Contraceptive Agents, Female ,North Carolina ,Humans ,Medicine ,Emergency contraception ,Prospective Studies ,030212 general & internal medicine ,education ,Contraception Behavior ,media_common ,Drug Implants ,education.field_of_study ,030219 obstetrics & reproductive medicine ,business.industry ,Intrauterine Devices, Medicated ,Obstetrics and Gynecology ,Abortion, Induced ,Family planning ,Delayed-Action Preparations ,Family medicine ,Pill ,Female ,business ,Developed country - Abstract
To evaluate whether contraceptive insurance coverage for women who present for an abortion is associated with obtaining long-acting reversible contraception or depot medroxyprogesterone acetate (DMPA) on the day the abortion is completed.We conducted a prospective cohort study of women presenting for medical or surgical abortion at a single health center in North Carolina. Eligible women were 18 years or older and fluent in English or Spanish. Data were from participant questionnaires, medical charts, and financial records. Our main exposure was whether the woman had insurance coverage for contraception at clinic intake. Our primary outcome was receiving DMPA, an intrauterine device, or a contraceptive subdermal implant on the same day of their surgical abortion or at the visit that determined their medication abortion was complete. We used univariable, bivariable, and multivariable analysis to report our findings.Five hundred seventy-five women enrolled in our cohort between September 2015 and April 2016. One hundred twenty-eight (22%) had insurance coverage and 447 (78%) did not. In the group with insurance coverage for contraception, 38% (49/128) received a long-acting reversible contraception method or DMPA compared with 7% (33/447) in the group without insurance coverage for contraception. After adjusting for confounding, women with contraceptive coverage were more than five times as likely to receive immediate postabortion contraception with one of these methods compared with women without coverage (relative risk 5.6, 95% confidence interval 3.8-8.3).Women with contraceptive insurance coverage on the day of their abortion were more likely to leave the abortion clinic with an intrauterine device or implant in place or receive DMPA injection compared with women without coverage.
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- 2017
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12. Structural and magnetic properties of DyCrO3.
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Sibanda, E. T., Prinsloo, A. R. E., Sheppard, C. J., and Mohanty, P.
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MAGNETIC properties , *MAGNETIC entropy , *NUCLEAR spin , *TRANSMISSION electron microscopy , *MAGNETIC fields , *MAGNETOCALORIC effects - Abstract
In this contribution, the structural and magnetic properties of DyCrO3 are studied, along with the magnetocaloric effect in this compound. The susceptibility as a function of temperature, χ(T), indicates that DyCrO3 has a G-type antiferromagnetic behaviour with weak ferromagnetism below Néel temperature, T N C r , at 147.1 ± 0.1 K, attributed to the ordering of Cr moments. The Dy moments orders antiferromagnetically below the spin reorientation temperature TSR = 4.81 ± 0.04 K. The dependence of magnetization on the applied magnetic field, M μ 0 H , shows a behaviour that corresponds to the χ(T) data. Arrott plots reflect the various magnetic orderings with a change in the gradient of the curves. For the first time, the magnetocaloric effect of sol-gel synthesized DyCrO3 is studied having an average particle size 215 ± 3 nm as obtained from transmission electron microscopy (TEM). Large magnetocaloric effects (MCE) are observed in the temperature range of 10 to 80 K for DyCrO3. The compound shows a relatively large magnetic entropy change (ΔSM) of 21 J.Kg−1.K−1 and relative cooling power (RCP) of 498 J.Kg−1 at 7 T and 10 K. Assuming the relations | Δ S m T , H | = a (H) n and R C P = C H 1 + 1 δ , with critical exponents n = 1 and δ → ∞ were obtained from the linearization, confirming the weak ferromagnetic behaviour. [ABSTRACT FROM AUTHOR]
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- 2022
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13. Structural and magnetic properties of DyCrO3.
- Author
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Sibanda, E. T., Prinsloo, A. R. E., Sheppard, C. J., and Mohanty, P.
- Subjects
MAGNETIC properties ,MAGNETIC entropy ,NUCLEAR spin ,TRANSMISSION electron microscopy ,MAGNETIC fields ,MAGNETOCALORIC effects - Abstract
In this contribution, the structural and magnetic properties of DyCrO
3 are studied, along with the magnetocaloric effect in this compound. The susceptibility as a function of temperature, χ(T), indicates that DyCrO3 has a G-type antiferromagnetic behaviour with weak ferromagnetism below Néel temperature, T N C r , at 147.1 ± 0.1 K, attributed to the ordering of Cr moments. The Dy moments orders antiferromagnetically below the spin reorientation temperature TSR = 4.81 ± 0.04 K. The dependence of magnetization on the applied magnetic field, M μ 0 H , shows a behaviour that corresponds to the χ(T) data. Arrott plots reflect the various magnetic orderings with a change in the gradient of the curves. For the first time, the magnetocaloric effect of sol-gel synthesized DyCrO3 is studied having an average particle size 215 ± 3 nm as obtained from transmission electron microscopy (TEM). Large magnetocaloric effects (MCE) are observed in the temperature range of 10 to 80 K for DyCrO3 . The compound shows a relatively large magnetic entropy change (ΔSM ) of 21 J.Kg−1 .K−1 and relative cooling power (RCP) of 498 J.Kg−1 at 7 T and 10 K. Assuming the relations | Δ S m T , H | = a (H) n and R C P = C H 1 + 1 δ , with critical exponents n = 1 and δ → ∞ were obtained from the linearization, confirming the weak ferromagnetic behaviour. [ABSTRACT FROM AUTHOR]- Published
- 2022
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14. Analysis of the sensitization profile towards allergens in central Africa
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Westritschnig, K., Sibanda, E., Thomas, W., Auer, H., Aspöck, H., Pittner, G., Vrtala, S., Spitzauer, S., Kraft, D., and Valenta, R.
- Published
- 2003
15. Polymorphism in codons 10 and 25 of the transforming growth factor-beta 1 (TGF-β1) gene in patients with invasive squamous cell carcinoma of the uterine cervix
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Stanczuk, G. A., Tswana, S. A., Bergstrom, S., and Sibanda, E. N.
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- 2002
16. Informing targeted HIV self-testing: a protocol for discrete choice experiments in Malawi, Zambia and Zimbabwe
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D'Elbee, M, Indravudh, P, Sibanda, E, Mwenge, L, Kumwenda, M, Choko, A, Maringwa, G, Johnson, C, Hatzold, K, Corbett, L, and Terris-Prestholt, F
- Abstract
Introduction HIV self-testing (HIVST) is a new approach to HIV testing where a person collects his or her own specimen, performs an HIV test and interprets the result, either alone or with someone he or she trusts. It is becoming increasingly relevant as a complement to standard-of-care HIV testing and is now recommended by the World Health Organization. Few studies have explored user preferences around HIVST service delivery and optimal models for increasing uptake and linkage to care, particularly among hard-to-reach populations. This paper describes an ongoing study that uses discrete choice experiments (DCE) to identify key HIVST service characteristics that drive people’s willingness to self-test for HIV and link to care, measure the relative strength of user preferences, and explore preference heterogeneity in Southern Africa. Method and Analysis Two DCEs – one on HIVST delivery and one on linkage to care after a positive self-test – are being administered in Malawi, Zambia and Zimbabwe. The designs in each country were informed by a qualitative study, which identified key HIVST service characteristics that influence user decision-making and refined scenario presentations and illustrations. Following data collection, DCE data will be analysed using a multinomial logit model as well as latent class, nested logit and generalised mixed models to examine heterogeneity in preferences by sociodemographic background, HIV testing experience and sexual behaviour. Ethics and dissemination The study has been approved by the College of Medicine Research Ethics Committee in Malawi, the Biomedical Ethics Committee of the University of Zambia, the Medical Research Council of Zimbabwe and the Research Ethics Committee of the London School of Hygiene and Tropical Medicine. Findings from the study will be presented at international conferences and in peer-reviewed journals. The results will help inform the HIVST implementation strategy in Southern Africa, particularly among populations underserved by standard-of-care services, such as men and young women.
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- 2018
17. Knowledge, attitudes and practices of health professionals in public health institutions on emergency contraception in Pietermaritzburg, KwaZulu-Natal Province, South Africa
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Sibanda, E, primary and Titus, M J, additional
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- 2017
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18. Method for diagnosing a viral infection
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Gallerano, Daniela, Valenta, R, and Sibanda, E.
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- 2014
19. Is socio-economic status a determinant of HIV-related stigma attitudes in Zimbabwe? Findings from Project Accept
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Mateveke, Kudzanai, primary, Singh, Basant, additional, Chingono, Alfred, additional, Sibanda, E., additional, and Machingura, Ian, additional
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- 2016
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20. Immunity to Co-Infections in Poverty-related and Neglected Infectious Diseases: Global Priorities for European Union Research Activities
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Abebe, M, Aseffa, A, Boraschi, D, Chiodi, F, Chisi, J, Del Prete, G, Doherty, Tm, Elhassan, I, Engers, H, Gyan, B, Harandi, A, Kariuki, T, Kironde, F, Kouriba, B, Laskay, T, Medaglini, D, Olesen, O, Palma, C, Sauerwein, R, Sibanda, E, Steinhoff, U, Tagliabue, A, Thiel, A, Vahedi, M, and Troye-Blomberg, M.
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- 2008
21. Sensitisation to three cockroach species in Southern Africa
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Andreas, Ludwig Lopata, Jeebhay, M. F., Groenewald, M., Manjra, A., Du Toit, G., Sibanda, E. N., Calvert, J., Lee, S., Schinkel, M., Fenemore, B., Motala, C., Potter, P. C., Division of Immunology, and Faculty of Health Sciences
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animal structures ,immune system diseases ,respiratory system ,respiratory tract diseases - Abstract
Cockroaches are important allergen sources in many countries, especially in the tropics. Cockroaches produce several allergens that are major risk factors for rhinitis and asthma. Worldwide, the prevalence of cockroach sensitivity varies between 30% and 70%.Geographical differences exist with regard to cockroach allergen exposure and sensitivity within countries and between countries. No data are available for Africa in this regard. Currently the diagnosis of cockroach sensitivity in southern Africa relies mainly on the detection of specific IgE to Blatella germanica (German cockroach), while a number of other species are found close to human dwellings. The aim of this study was to investigate the prevalence and distribution of sensitisation to three different cockroach species among subjects residing in four different geographical regions in southern Africa. Strong IgE reactivity particular to B. germanica was found among subjects residing in Pretoria and Harare. By contrast strong IgE responses to other cockroach species, Periplaneta americana and Blatta orientalis, were observed in subjects living in Cape Town and Durban. The levels of specific IgE antibodies to all three cockroach species appeared to be higher in Cape Town than those from the other three cities investigated. Monosensitivity to all three cockroach species was observed and minimal cross-reactivity to house-dust mite. These data show that allergy to P. americana and B. orientalis are an important diagnostic consideration in temperate and coastal regions of southern Africa, whereas sensitisation to B. germanica appears to predominate in regions of higher altitude such as Pretoria and Harare.
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- 2005
22. Immunity against HIV/AIDS, Malaria, and Tuberculosis during Co-Infections with Neglected Infectious Diseases: Recommendations for the European Union Research Priorities.
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Boraschi, D., Alemayehu, M.A., Aseffa, A., Chiodi, F., Chisi, J., Prete, G. Del, Doherty, T.M., Elhassan, I., Engers, H., Gyan, B, Harandi, A.M., Kariuki, T., Kironde, F., Kouriba, B., Langhorne, J., Laskay, T., Medaglini, D., Olesen, O., Onyebujoh, P., Palma, C., Sauerwein, R.W., Sibanda, E., Steinhoff, U., Tagliabue, A., Thiel, A., Vahedi, M., Troye-Blomberg, M., Boraschi, D., Alemayehu, M.A., Aseffa, A., Chiodi, F., Chisi, J., Prete, G. Del, Doherty, T.M., Elhassan, I., Engers, H., Gyan, B, Harandi, A.M., Kariuki, T., Kironde, F., Kouriba, B., Langhorne, J., Laskay, T., Medaglini, D., Olesen, O., Onyebujoh, P., Palma, C., Sauerwein, R.W., Sibanda, E., Steinhoff, U., Tagliabue, A., Thiel, A., Vahedi, M., and Troye-Blomberg, M.
- Abstract
Contains fulltext : 69872.pdf (publisher's version ) (Open Access), Author SummaryInfectious diseases remain a major health and socioeconomic problem in many low-income countries, particularly in sub-Saharan Africa. For many years, the three most devastating diseases, HIV/AIDS, malaria, and tuberculosis (TB) have received most of the world's attention. However, in rural and impoverished urban areas, a number of infectious diseases remain neglected and cause massive suffering. It has been calculated that a group of 13 neglected infectious diseases affects over one billion people, corresponding to a sixth of the world's population. These diseases include infections with different types of worms and parasites, cholera, and sleeping sickness, and can cause significant mortality and severe disabilities in low-income countries. For most of these diseases, vaccines are either not available, poorly effective, or too expensive. Moreover, these neglected diseases often occur in individuals who are also affected by HIV/AIDS, malaria, or TB, making the problem even more serious and indicating that co-infections are the rule rather than the exception in many geographical areas. To address the importance of combating co-infections, scientists from 14 different countries in Africa and Europe met in Addis Ababa, Ethiopia, on September 9-11, 2007. The message coming from these scientists is that the only possibility for winning the fight against infections in low-income countries is by studying, in the most global way possible, the complex interaction between different infections and conditions of malnourishment. The new scientific and technical tools of the post-genomic era can allow us to reach this goal. However, a concomitant effort in improving education and social conditions will be needed to make the scientific findings effective.
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- 2008
23. Changes in neutrophil count, creatine kinase and muscle soreness after repeated bouts of downhill running
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Smith, LL, Semple, SJ, McKune, AJ, Neveling, N, Caldeira, M, Swanepoel, JM, Tsomele, L, Naidoo, M, Sibanda, E, Smith, LL, Semple, SJ, McKune, AJ, Neveling, N, Caldeira, M, Swanepoel, JM, Tsomele, L, Naidoo, M, and Sibanda, E
- Abstract
ObjectiveA primary objective was to examine circulating neutrophil count after repeated bouts of downhill running. An additional aim was to determine creatine kinase (CK) levels during the initial 12 hours, after repeated DHRs.DesignEleven healthy, untrained Caucasian males performed 2 x 60 min bouts of DHR (-13.5%), spaced 14 days apart, at a speed equal to 75% VO2max on a level grade. Blood was collected before, after, and every hour for 12hours, and every 24 hours for 6 days. Absolute neutrophil count, CK, and delayed-onset muscle soreness (DOMS) were assessed. Results were analysed using repeated measures ANOVA (p<0.05) with appropriate post hoc tests.ResultsThere were no significant differences in neutrophil count (p=0.24) during the 12-h period following run 1 (mean±se, 6.45±0.29 10-9.l-1) versus run 2 (5.96±0.09 10-9.l-1), or during the 24-h periods for run 1 (3.48±0.0910-9.l-1) or run 2 (3.47±0.09 10-9.l-1). During the initial 12-h period, there was a significant interaction effect (p=0.0001) for CK with differences between bouts seen between 3 - 12 h; differences remained evident at 24 h and at 96 - 144 h. In all muscle groups, DOMS was significantly lowerafter run 2 compared with run 1.ConclusionThe lack of significance in neutrophils, as well as the early onset of difference in CK between run 1 and run 2 were attributed to the type of eccentric protocol used. It was proposed that future studies be more cognisant of whether the eccentric mode is predominantly low-intensitylong-duration or high-intensity short-duration.
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- 2007
24. Changes in serum cytokines after repeated bouts of downhill running
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Smith, LL, McKune, AJ, Semple, SJ, Sibanda, E, Steel, H, Anderson, R, Smith, LL, McKune, AJ, Semple, SJ, Sibanda, E, Steel, H, and Anderson, R
- Abstract
The purpose of this study was to examine changes in serum cytokines after repeated bouts of aerobically biased eccentric exercise. Six untrained males ran down a -13.5% treadmill grade for 60 min on two occasions (RUN1 and RUN2) at a speed equal to 75% of their VO2 peak on a level grade; runs were spaced 14 d apart. Serum was collected before, after, and every hour for 12 h, and every 24 h for 6 d. Cytokines were assessed using 17 multiplex bead technology (Bio-Rad). Creatine kinase (CK) and delayed-onset muscle soreness (DOMS) were assessed before and 24-120 h after. Results were analyzed using a repeated measures analysis of variance (p
- Published
- 2007
25. A context extinction account of outcome density & depressive realism effects.
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Msetfi, Rachel M., Sibanda, E., Murphy, R. A., Msetfi, Rachel M., Sibanda, E., and Murphy, R. A.
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- 2005
26. Facilitators and barriers to cotrimoxazole and nevirapine prophylaxis among HIV exposed babies: a qualitative study from Harare, Zimbabwe
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Sibanda, E, primary, Weller, I, additional, Bernays, S, additional, Hakim, J, additional, and Cowan, F, additional
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- 2012
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27. Does Trimethoprim-Sulfamethoxazole Prophylaxis for HIV Induce Bacterial Resistance to Other Antibiotic Classes?: Results of a Systematic Review
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Sibanda, E. L., primary, Weller, I. V. D., additional, Hakim, J. G., additional, and Cowan, F. M., additional
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- 2011
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28. Emotional intelligence and leadership abilities
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Herbst, H H, primary, Maree, J G, additional, and Sibanda, E, additional
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- 2008
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29. Changes in neutrophil count, creatine kinases and muscle soreness after repeated bouts of downhill running
- Author
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Smith, LL, primary, Semple, SJ, additional, McKune, AJ, additional, Neveling, N, additional, Caldeira, M, additional, Swanepoel, J-M, additional, Tsomele, L, additional, Naidoo, M, additional, and Sibanda, E, additional
- Published
- 2007
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30. HIV infection reduces skin graft survival in burn injuries: a prospective study
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Mzezewa, S, primary, Jönsson, K, additional, Sibanda, E, additional, Åberg, M, additional, and Salemark, L, additional
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- 2003
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31. Polymorphism at the -308-promoter position of the tumor necrosis factor-alpha (TNF-alpha) gene and cervical cancer
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Stanczuk, G. A., primary, Sibanda, E. N., additional, Tswana, S. A., additional, and Bergstrom, S., additional
- Published
- 2003
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32. Polymorphism at the –308-promoter position of the tumor necrosis factor-alpha (TNF-α) gene and cervical cancer
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Stanczuk, G. A., primary, Sibanda, E. N., additional, Tswana, S. A., additional, and Bergstrom, S., additional
- Published
- 2003
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33. Antiretroviral (ARV) drug utilization in Harare
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Nyazema, N Z, primary, Khoza, S, additional, Landman, I, additional, Sibanda, E, additional, and Gael, K, additional
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- 2000
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34. Plasma HIV-1 RNA quantitation in HIV infected adult Zimbabweans
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Chaka, W S, additional and Sibanda, E N, additional
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- 1999
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35. Aero-allergen sensitisation patterns amongst atopic Zimbabwe children
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Kambarami, R A, primary, Marechera, F, additional, Sibanda, E N, additional, and Chitiyo, M E, additional
- Published
- 1999
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36. Changes in serum cytokines after repeated bouts of downhill running.
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Smith LL, McKune AJ, Semple SJ, Sibanda E, Steel H, and Anderson R
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- 2007
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37. Changes in serum cytokines after repeated bouts of downhill running
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Ll, Smith, Andrew McKune, Sj, Semple, Sibanda E, Steel H, and Anderson R
38. An assessment of the Zimbabwe ministry of health and child welfare provider initiated HIV testing and counselling programme
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Sibanda Euphemia L, Hatzold Karin, Mugurungi Owen, Ncube Getrude, Dupwa Beatrice, Siraha Pester, Madyira Lydia K, Mangwiro Alexio, Bhattacharya Gaurav, and Cowan Frances M
- Subjects
Public aspects of medicine ,RA1-1270 - Abstract
Abstract Background Provider-initiated HIV testing and counselling (PITC) is widely recommended to ensure timely treatment of HIV. The Zimbabwe Ministry of Health introduced PITC in 2007. We aimed to evaluate institutional capacity to implement PITC and investigate patient and health care worker (HCW) perceptions of the PITC programme. Methods Purposive selection of health care institutions was conducted among those providing PITC. Study procedures included 1) assessment of implementation procedures and institutional capacity using a semi-structured questionnaire; 2) in-depth interviews with patients who had been offered HIV testing to explore perceptions of PITC, 3) Focus group discussions with HCW to explore views on PITC. Qualitative data was analysed according to Framework Analysis. Results Sixteen health care institutions were selected (two central, two provincial, six district hospitals; and six primary care clinics). All institutions at least offered PITC in part. The main challenges which prevented optimum implementation were shortages of staff trained in PITC, HIV rapid testing and counselling; shortages of appropriate counselling space, and, at the time of assessment, shortages of HIV test kits. Both health care workers and patients embraced PITC because they had noticed that it had saved lives through early detection and treatment of HIV. Although health care workers reported an increase in workload as a result of PITC, they felt this was offset by the reduced number of HIV-related admissions and satisfaction of working with healthier clients. Conclusion PITC has been embraced by patients and health care workers as a life-saving intervention. There is need to address shortages in material, human and structural resources to ensure optimum implementation.
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- 2012
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39. An exposition of traditional Zulu understanding of reality.
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Sibanda, E.
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- ZULU Thought-Patterns & Symbolism (Book)
- Abstract
Reviews the book `Zulu Thought-Patterns and Symbolism,' by Axel-Ivar Berglund.
- Published
- 1991
40. Characterisation of allergic reactivity to fungi in a Zimbabwean population
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Pfavayi, LT, Mutapi, F, Baker, S, Woolhouse, M, and Sibanda, E
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Allergy ,Epidemiology ,Africa ,Mycology - Abstract
While fungal diseases are a growing global problem, there remains a paucity of epidemiological data in most developing countries. Hence, this thesis aimed to investigate the epidemiology, immunology, and aetiology of fungal allergic diseases in Zimbabwe. This study demonstrated that the burden of fungal diseases in Zimbabwe is high (14%), with tinea capitis being the most prevalent condition. The country's background sensitivity to fungal allergens and the effect of host-related factors was unknown. Therefore, this thesis further investigated the prevalence of fungal sensitisation and reactivity among Zimbabwean children and how the gut mycobiome composition affected these, whilst considering the effects of host age, gender, and Schistosoma haematobium infection status. The prevalence of fungal sensitisation to ≥1 fungal species was 96%, and the metagenomic analysis of the gut mycobiome showed that the mycobiome comprised Due to the high prevalence of fungal sensitisation, this thesis further identified and characterised fungal proteins that were immunoreactive against serum samples from fungal-sensitised children. Furthermore, the utility of a specific Aspergillus fumigatus allergen (Asp f 2) peptide in the differential diagnosis of fungal allergy was evaluated. As a result, novel immunogens from fungi were discovered, potentially increasing the number of known fungal allergens. The Asp f 2 peptide was demonstrated to be an inadequate indicator for diagnosing fungal allergy in the population. Taken together, the findings of this thesis add to the ongoing global discussions about the burden of fungal diseases. Furthermore, it provides novel data on several important aspects of fungal allergy that must be evaluated and validated since they may have implications for the care of allergic individuals.
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- 2023
41. Extreme weather events and disruptions to HIV services: a systematic review.
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Iwuji CC, McMichael C, Sibanda E, Orievulu KS, Austin K, and Ebi KL
- Abstract
Background: Extreme weather events pose a risk to health and disproportionately affect vulnerable groups, such as people living with HIV. We aimed to investigate the effects of extreme weather events on HIV testing uptake, HIV treatment and care, and HIV transmission., Methods: For this systematic review, we searched PubMed, Web of Science, and PsycINFO for peer-reviewed studies published between database inception and Aug 31, 2023. Eligible studies were English-language qualitative, quantitative observational (retrospective, prospective, cross-sectional, longitudinal, case-control, and cohort), and mixed-method studies, and randomised controlled trials related to HIV and extreme weather events. We excluded reviews, mathematical models, and case reports. After exporting the search results, two authors independently screened the titles and abstracts of identified articles, reviewing the full text of those that met the inclusion criteria. We used systems thinking to develop a framework linking extreme weather events and HIV and summarised the results using thematic narrative synthesis., Findings: Of the 6126 studies identified by the search, 27 met the inclusion criteria and were eligible for analysis, of which 19 were quantitative, six were qualitative, and two were mixed-method studies. We identified five main themes linking extreme weather events to HIV: economic and livelihood conditions (12 studies), psychosocial factors (19 studies), infrastructure damage and operational challenges (17 studies), migration and displacement (ten studies), and associated medical conditions and health-care needs (12 studies). We showed how these themes interact in complex ways, resulting in a reduction in uptake of HIV testing, interruption of HIV care and subsequent disease progression, altered risk behaviours, and an increased prevalence of HIV., Interpretation: Extreme weather events are associated with disruptions to HIV services. Owing to the design of the included studies, we could not establish a causal relationship between extreme weather events and HIV incidence, highlighting a research gap. Appropriate adaptations and mitigation policies that protect the health and wellbeing of people living with HIV during and after extreme weather events are warranted. Such actions will be crucial to achieving the UNAIDS goal of ending HIV as a public health threat by 2030., Funding: None., Competing Interests: Declaration of interests CCI received grant funding (paid to his institution) for investigator-sponsored research from Gilead Sciences and support from the International Vaccine Institute to attend the Indo-Pacific Climate Resilience Forum. All other authors declare no competing interests., (Copyright © 2024 Elsevier Ltd. All rights reserved, including those for text and data mining, AI training, and similar technologies.)
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- 2024
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42. Differentiated care for youth in Zimbabwe: Outcomes across the HIV care cascade.
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Dziva Chikwari C, Kranzer K, Simms V, Patel A, Tembo M, Mugurungi O, Sibanda E, Mufare O, Ndlovu L, Muzangwa J, Vundla R, Chibaya A, Hayes R, Mackworth-Young C, Bernays S, Mavodza C, Hove F, Bandason T, Dauya E, and Ferrand RA
- Abstract
Youth living with HIV are at higher risk than adults of disengaging from HIV care. Differentiated models of care such as community delivery of antiretroviral therapy (ART) may improve treatment outcomes. We investigated outcomes across the HIV cascade among youth accessing HIV services in a community-based setting. This study was nested in a cluster-randomised controlled trial (CHIEDZA: Clinicaltrials.gov, Registration Number: NCT03719521) conducted in three provinces in Zimbabwe and aimed to investigate the impact of a youth-friendly community-based package of HIV services, integrated with sexual and reproductive health services for youth (16-24 years), on population-level HIV viral load (VL). HIV services included HIV testing, ART initiation and continuous care, VL testing, and adherence support. Overall 377 clients were newly diagnosed with HIV at CHIEDZA, and linkage to HIV care was confirmed for 265 (70.7%, 234 accessed care at CHIEDZA and 31 with other providers); of these 250 (94.3%) started ART. Among those starting ART at CHIEDZA who did not transfer out and had enough follow up time (>6 months), 38% (68/177) were lost-to-follow-up within six months. Viral suppression (HIV Viral Load <1000 copies/ml) among those who had a test at 6 months was 90% (96/107). In addition 1162 clients previously diagnosed with HIV accessed CHIEDZA; 714 (61.4%) had a VL test, of whom 565 (79.1%) were virally suppressed. This study shows that provision of differentiated services for youth in the community is feasible. Linkage to care and retention during the initial months of ART was the main challenge and needs concerted attention to achieve the ambitious 95-95-95 UNAIDS targets., Competing Interests: I have read the journal’s policy and the authors of this manuscript have the following competing interests: Chido Dziva Chikwari has been a guest Editor for Plos Global Public Health. The other authors have declared that no competing interests exist., (Copyright: © 2024 Dziva Chikwari et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
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- 2024
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43. Exploring COVID-19 vaccine uptake among healthcare workers in Zimbabwe: A mixed methods study.
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Taruvinga T, Chingono RS, Marambire E, Larsson L, Olaru ID, Sibanda S, Nzvere F, Redzo N, Ndhlovu CE, Rusakaniko S, Mujuru H, Sibanda E, Chonzi P, Siamuchembu M, Chikodzore R, Mahomva A, Ferrand RA, Dixon J, and Kranzer K
- Abstract
With COVID-19 no longer categorized as a public health emergency of international concern, vaccination strategies and priority groups for vaccination have evolved. Africa Centres for Diseases Prevention and Control proposed the '100-100-70%' strategy which aims to vaccinate all healthcare workers, all vulnerable groups, and 70% of the general population. Understanding whether healthcare workers were reached during previous vaccination campaigns and what can be done to address concerns, anxieties, and other influences on vaccine uptake, will be important to optimally plan how to achieve these ambitious targets. In this mixed-methods study, between June 2021 and July 2022 a quantitative survey was conducted with healthcare workers accessing a comprehensive health check in Zimbabwe to determine whether and, if so, when they had received a COVID-19 vaccine. Healthcare workers were categorized as those who had received the vaccine 'early' (before 30.06.2021) and those who had received it 'late' (after 30.06.2021). In addition, 17 in-depth interviews were conducted to understand perceptions and beliefs about COVID-19 vaccines. Of the 3,086 healthcare workers employed at 43 facilities who participated in the study, 2,986 (97%, 95% CI [92%-100%]) reported that they had received at least one vaccine dose. Geographical location, older age, higher educational attainment and having a chronic condition was associated with receiving the vaccine early. Qualitatively, (mis)information, infection risk perception, quasi-mandatory vaccination requirements, and legitimate concerns such as safety and efficacy influenced vaccine uptake. Meeting the proposed 100-100-70 target entails continued emphasis on strong communication while engaging meaningfully with healthcare workers' concerns. Mandatory vaccination may undermine trust and should not be a substitute for sustained engagement., Competing Interests: The authors have declared that no competing interests exist., (Copyright: © 2023 Taruvinga et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
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- 2023
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44. Potential cost-effectiveness of community availability of tenofovir, lamivudine, and dolutegravir for HIV prevention and treatment in east, central, southern, and west Africa: a modelling analysis.
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Phillips AN, Bansi-Matharu L, Shahmanesh M, Hargreaves JR, Smith J, Revill P, Sibanda E, Ehrenkranz P, Sikwese K, Rodger A, Lundgren JD, Gilks CF, Godfrey C, Cowan F, and Cambiano V
- Subjects
- Male, Female, Humans, Tenofovir therapeutic use, Cost-Benefit Analysis, Africa, Western, Lamivudine therapeutic use, HIV Infections drug therapy, HIV Infections prevention & control
- Abstract
Background: Post-exposure prophylaxis (PEP) offers protection from HIV after condomless sex, but is not widely available in a timely manner in east, central, southern, and west Africa. To inform the potential pilot implementation of such an approach, we modelled the effect and cost-effectiveness of making PEP consisting of tenofovir, lamivudine, and dolutegravir (TLD) freely and locally available in communities without prescription, with the aim of enabling PEP use within 24 h of condomless sex. Free community availability of TLD (referred to as community TLD) might also result in some use of TLD as pre-exposure prophylaxis (PrEP) and as antiretroviral therapy for people living with HIV., Methods: Using an existing individual-based model (HIV Synthesis), we explicitly modelled the potential positive and negative effects of community TLD. Through the sampling of parameter values we created 1000 setting-scenarios, reflecting the uncertainty in assumptions and a range of settings similar to those seen in east, central, southern, and west Africa (with a median HIV prevalence of 14·8% in women and 8·1% in men). For each setting scenario, we considered the effects of community TLD. TLD PEP was assumed to have at least 90% efficacy in preventing HIV infection after condomless sex with a person living with HIV., Findings: The modelled effects of community TLD availability based on an assumed high uptake of TLD resulted in a mean reduction in incidence of 31% (90% range over setting scenarios, 6% increase to 57% decrease) over 20 years, with an HIV incidence reduction over 50 years in 91% of the 1000 setting scenarios, deaths averted in 55% of scenarios, reduction in costs in 92% of scenarios, and disability-adjusted life-years averted in 64% of scenarios with community TLD. Community TLD was cost-effective in 90% of setting scenarios and cost-saving (with disability-adjusted life-years averted) in 58% of scenarios. When only examining setting scenarios in which there was lower uptake of community TLD, community TLD is cost-effective in 92% of setting scenarios., Interpretation: The introduction of community TLD, enabling greater PEP access, is a promising approach to consider further in pilot implementation projects., Funding: Bill & Melinda Gates Foundation to the HIV Modelling Consortium., Competing Interests: Declaration of interests ANP reports a research grant from the Bill & Melinda Gates Foundation for the current work; and grants from Wellcome, the National Institutes for Health, and European Commission outside this work. FC reports grants from the Wellcome Trust, the Bill & Melinda Gates Foundation, the Medical Research Council, the National Institute for Mental Health, UNICEF, and UNAIDS to support travel for expert panel meetings; being a board member for UK Research and Innovation Global Health Research Board and African Research Leaders Fellowship Schemes; and being a member on a WHO Expert Panel. LB-M reports a research grant from Bill & Melinda Gates Foundation for the current work. VC reports grants from UK Research Institute, the National Institute for Mental Health, United States Agency for International Development, Medical Research Council, and the Bill & Melinda Gates Foundation. JRH reports grants from the Bill & Melinda Gates Foundation and Wellcome and consulting fees from Gavi. This Article was written by CG in her capacity as a US Government employee, but the views expressed in this paper do not represent those of the Department of State or the Centers for Disease Control and Prevention. All other authors declare no competing interests., (Copyright © 2023 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license. Published by Elsevier Ltd.. All rights reserved.)
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- 2023
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45. COVID-19 self-testing using antigen rapid diagnostic tests: Feasibility evaluation among health-care workers and general population in Malawi.
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Mukoka M, Sibanda E, Watadzaushe C, Kumwenda M, Abok F, Corbett EL, Ivanova E, and Choko AT
- Subjects
- Adult, Humans, Female, Male, Malawi epidemiology, Cross-Sectional Studies, Feasibility Studies, Self-Testing, SARS-CoV-2, Sensitivity and Specificity, COVID-19 Testing, COVID-19 diagnosis, COVID-19 epidemiology
- Abstract
Background: COVID-19 testing is critical for identifying cases to prevent transmission. COVID-19 self-testing has the potential to increase diagnostic testing capacity and to expand access to hard-to-reach areas in low-and-middle-income countries. We investigated the feasibility and acceptability of COVID-19 self-sampling and self-testing using SARS-CoV-2 Antigen-Rapid Diagnostic Tests (Ag-RDTs)., Methods: From July 2021 to February 2022, we conducted a mixed-methods cross-sectional study examining self-sampling and self-testing using Standard Q and Panbio COVID-19 Ag Rapid Test Device in Urban and rural Blantyre, Malawi. Health care workers and adults (18y+) in the general population were non-randomly sampled., Results: Overall, 1,330 participants were enrolled of whom 674 (56.0%) were female and 656 (54.0%) were male with 664 for self-sampling and 666 for self-testing. Mean age was 30.7y (standard deviation [SD] 9.6). Self-sampling usability threshold for Standard Q was 273/333 (82.0%: 95% CI 77.4% to 86.0%) and 261/331 (78.8%: 95% CI 74.1% to 83.1%) for Panbio. Self-testing threshold was 276/335 (82.4%: 95% CI 77.9% to 86.3%) and 300/332 (90.4%: 95% CI 86.7% to 93.3%) for Standard Q and Panbio, respectively. Agreement between self-sample results and professional test results was 325/325 (100%) and 322/322 (100%) for Standard Q and Panbio, respectively. For self-testing, agreement was 332/333 (99.7%: 95% CI 98.3 to 100%) for Standard Q and 330/330 (100%: 95% CI 99.8 to 100%) for Panbio. Odds of achieving self-sampling threshold increased if the participant was recruited from an urban site (odds ratio [OR] 2.15 95% CI 1.44 to 3.23, P < .01. Compared to participants with primary school education those with secondary and tertiary achieved higher self-testing threshold OR 1.88 (95% CI 1.17 to 3.01), P = .01 and 4.05 (95% CI 1.20 to13.63), P = .02, respectively., Conclusions: One of the first studies to demonstrate high feasibility and acceptability of self-testing using SARS-CoV-2 Ag-RDTs among general and health-care worker populations in low- and middle-income countries potentially supporting large scale-up. Further research is warranted to provide optimal delivery strategies of self-testing., Competing Interests: The authors have declared that no competing interests exist., (Copyright: © 2023 Mukoka et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
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- 2023
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46. Delivery of index-linked HIV testing for children: learnings from a qualitative process evaluation of the B-GAP study in Zimbabwe.
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Dringus S, Davis K, Simms V, Bernays S, Redzo N, Bandason T, Chikodzore R, Sibanda E, Webb K, Ncube G, Kranzer K, Ferrand RA, and Dziva Chikwari C
- Subjects
- Child, Humans, Social Stigma, Zimbabwe, National Health Programs organization & administration, National Health Programs statistics & numerical data, Demography, Male, Female, Infant, Child, Preschool, Adolescent, Adult, HIV Infections diagnosis, HIV Testing methods, HIV Testing standards
- Abstract
Background: Index-linked HIV testing for children, whereby HIV testing is offered to children of individuals living with HIV, has the potential to identify children living with undiagnosed HIV. The "Bridging the Gap in HIV Testing and Care for Children in Zimbabwe" (B-GAP) study implemented and evaluated the provision of index-linked HIV testing for children aged 2-18 years in Zimbabwe. We conducted a process evaluation to understand the considerations for programmatic delivery and scale-up of this strategy., Methods: We used implementation documentation to explore experiences of the field teams and project manager who delivered the index-linked testing program, and to describe barriers and facilitators to index-linked testing from their perspectives. Qualitative data were drawn from weekly logs maintained by the field teams, monthly project meeting minutes, the project coordinator's incident reports and WhatsApp group chats between the study team and the coordinator. Data from each of the sources was analysed thematically and synthesised to inform the scale-up of this intervention., Results: Five main themes were identified related to the implementation of the intervention: (1) there was reduced clinic attendance of potentially eligible indexes due to community-based differentiated HIV care delivery and collection of HIV treatment by proxy individuals; (2) some indexes reported that they did not live in the same household as their children, reflecting the high levels of community mobility; (3) there were also thought to be some instances of 'soft refusal'; (4) further, delivery of HIV testing was limited by difficulties faced by indexes in attending health facilities with their children for clinic-based testing, stigma around community-based testing, and the lack of familiarity of indexes with caregiver provided oral HIV testing; (5) and finally, test kit stockouts and inadequate staffing also constrained delivery of index-linked HIV testing., Conclusions: There was attrition along the index-linked HIV testing cascade of children. While challenges remain at all levels of implementation, programmatic adaptations of index-linked HIV testing approaches to suit patterns of clinic attendance and household structures may strengthen implementation of this strategy. Our findings highlight the need to tailor index-linked HIV testing to subpopulations and contexts to maximise its effectiveness., (© 2023. The Author(s).)
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- 2023
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47. Diagnostic options for pulmonary fungal diseases in Africa.
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Mushi MF, Zaki SM, Penney ROS, Bamba S, Ngouanom Kuate MP, Kasamba EL, Amona FM, Werkneh S, Ceesay B, Dibba B, Ocansey B, Sy O, Yahaya M, Jiba D, Boyles T, Mkumbaye SI, Kwizera R, Sibanda E, Koffi D, Sissinto Savi De Tove Y, Orefuwa E, and Denning DW
- Abstract
Background: Fungal lung diseases are global in distribution and require specific tests for diagnosis. We report a survey of diagnostic service provision in Africa., Methods: A written questionnaire was followed by a video conference call with each respondent(s) and external validation. To disseminate the questionnaire, a snowball sample was used., Results: Data were successfully collected from 50 of 51 African countries with populations >1 million. The questionnaire was completed by respondents affiliated with 72 health facilities. Of these 72 respondents, 33 (45.8%) reported data for the whole country while others reported data for a specific region/province within their country. In the public sector, chest X-ray and computed tomography are performed often in 49 countries (98%) and occasionally in 37 countries (74%), and less often in the private sector. Bronchoscopy and spirometry were done often in 28 countries (56%) and occasionally in 18 countries (36%) in the tertiary health facilities of public sector. The most conducted laboratory diagnostic assay was fungal culture (often or occasionally) in 29 countries (58%). In collaboration with the Africa Centre for Disease Control and Prevention, regional webinars and individual country profiles provided further data validation., Conclusion: This survey has found a huge disparity of diagnostic test capability across the African continent. Some good examples of good diagnostic provision and very high-quality care were seen, but this was unusual. The unavailability of essential testing such as spirometry was noted, which has a high impact in the diagnosis of lung diseases. It is important for countries to implement tests based on the World Health Organization Essential Diagnostics List., Competing Interests: Conflict of interest: All authors declare no conflict of interest., (Copyright ©The authors 2023.)
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- 2023
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48. Human rights violations among men who have sex with men and transgender people in South Africa.
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Chimatira R, Jebese-Mfenqe D, Chikwanda J, Sibanda E, Thengwa Q, Futshane B, and Gaga S
- Abstract
Background: Men who have sex with men (MSM) and transgender (TG) people face human rights violations (HRVs) which impact their access to critical interventions for HIV prevention, treatment, and related services., Objectives: This study describes how Beyond Zero, a not-for-profit organisation in South Africa, built an HRV reporting system and discusses data on the HRVs experienced by MSM and TG people who accessed HIV prevention services between 01 January 2021 and 31 December 2021., Method: This was a cross-sectional study using secondary analysis of programmatic data routinely collected as part of HIV prevention programmes for MSM and TG in 10 rural districts of South Africa., Results: A total of 249 individuals reported having experienced HRVs. Of these, 113 (54.6%) were physical violations, 145 (58.2%) were psychosocial harassment, 15 (18.3%) were experienced within the workplace, and 59 (23.7%) were experienced at a healthcare or social services institution. Overall, 77% of the physical violations and 70.4% of the psychosocial violations occurred in the home and local community settings; 76.1% of the perpetrators of physical violence and 79.3% of the perpetrators of psychosocial harassment were known. Most incidents of physical violence (80.5%) and psychosocial harassment (92.4%) were not reported due to fear of homophobic or transphobic violence., Conclusion: Our findings demonstrate the feasibility of documenting HRVs among MSM and TG people within HIV prevention programmes. Men who have sex with men and TG people should be systematically screened for HRVs and linked to legal or other services., What This Study Adds: Our findings present data on the nature of HRVs in 10 districts outside of the large urban centres where research documenting the lived experiences of MSM, TG people and other key populations is traditionally conducted in South Africa. This data contribute to addressing the gap in the literature on the needs of MSM and TG people in South Africa caused by the delayed inclusion of rural MSM and TG people in research., Competing Interests: The authors declare that they have no financial or personal relationships that may have inappropriately influenced them in writing this article., (© 2023. The Authors.)
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- 2023
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49. Heavy Rainfall and HIV and Sexually Transmitted Infections in Sub-Saharan Africa-Potential New Risk.
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Ebi KL and Sibanda E
- Subjects
- Africa South of the Sahara epidemiology, Humans, HIV Infections epidemiology, Sexually Transmitted Diseases epidemiology
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- 2022
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50. Enabling timely HIV postexposure prophylaxis access in sub-Saharan Africa.
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Phillips AN, Sibanda E, Sikwese K, Bansi-Matharu L, Cambiano V, Rodger A, Lundgren J, Shahmanesh M, Gilks C, Godfrey C, Ehrenkranz P, Hargreaves JR, Revill P, and Cowan F
- Subjects
- Africa South of the Sahara, Humans, Anti-HIV Agents therapeutic use, HIV Infections drug therapy, HIV Infections prevention & control
- Published
- 2022
- Full Text
- View/download PDF
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