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Advances in sequencing technologies have led to the rapid growth of multi-omics data on rheumatoid arthritis (RA). However, a comprehensive database that systematically collects and classifies the scattered data is still lacking. Here, we developed the Rheumatoid Arthritis Bioinformatics Center (RABC, http://www.onethird-lab.com/RABC/), the first multi-omics data resource platform (data hub) for RA. There are four categories of data in RABC: (i) 175 multi-omics sample sets covering transcriptome, epigenome, genome, and proteome; (ii) 175 209 differentially expressed genes (DEGs), 105 differentially expressed microRNAs (DEMs), 18 464 differentially DNA methylated (DNAm) genes, 1 764 KEGG pathways, 30 488 GO terms, 74 334 SNPs, 242 779 eQTLs, 105 m6A-SNPs and 18 491 669 meta-mQTLs; (iii) prior knowledge on seven types of RA molecular markers from nine public and credible databases; (iv) 127 073 literature information from PubMed (from 1972 to March 2022). RABC provides a user-friendly interface for browsing, searching and downloading these data. In addition, a visualization module also supports users to generate graphs of analysis results by inputting personalized parameters. We believe that RABC will become a valuable resource and make a significant contribution to the study of RA.

The surveying achievement is the basis for managing the urban real estate, the currency and accuracy of which are the two preconditions to increase efficiency for management of real estate. Based on the validity of surveying data in urban real estate, this paper is to explore the overall method and mechanism for the change of surveying achievements. With the practical experience, operable measures could be proposed for increasing the management ability of urban real estate in China.

In the recent years, tourism destination has been the research hotspot because of its importance in tourism. As the principal part and foundation of tourism activities, tourists are a major source of profit throughout the industry. Considering the lack of tourism destination evaluation, we decide to research it. In this paper, we put forward the tourism destination evaluation mechanism construction from the perspective of tourists and make dynamic comprehensive evaluation of tourism destination by using analytic hierarchy process.