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Background Distinguishing parotid pleomorphic adenoma (PPA) from parotid adenolymphoma (PA) is important for precision treatment, but there is a lack of readily available diagnostic methods. In this study, we aimed to explore the diagnostic value of radiomic signatures based on magnetic resonance imaging (MRI) for PPA and PA. Methods The clinical characteristic and imaging data were retrospectively collected from 252 cases (126 cases in the training cohort and 76 patients in the validation cohort) in this study. Radiomic features were extracted from MRI scans, including T1-weighted imaging (T1WI) sequences and T2-weighted imaging (T2WI) sequences. The radiomic features from three sequences (T1WI, T2WI and T1WI combined with T2WI) were selected using univariate analysis, LASSO correlation and Spearman correlation. Then, we built six quantitative radiomic models using the selected features through two machine learning methods (multivariable logistic regression, MLR, and support vector machine, SVM). The performances of the six radiomic models were assessed and the diagnostic efficacies of the ideal T1-2WI radiomic model and the clinical model were compared. Results The T1-2WI radiomic model using MLR showed optimal discriminatory ability (accuracy = 0.87 and 0.86, F-1 score = 0.88 and 0.86, sensitivity = 0.90 and 0.88, specificity = 0.82 and 0.80, positive predictive value = 0.86 and 0.84, negative predictive value = 0.86 and 0.84 in the training and validation cohorts, respectively) and its calibration was observed to be good (p > 0.05). The area under the curve (AUC) of the T1-2WI radiomic model was significantly better than that of the clinical model for both the training (0.95 vs. 0.67, p p = 0.001) cohorts. Conclusions The T1-2WI radiomic model in our study is complementary to the current knowledge of differential diagnosis for PPA and PA.

Additional file 1: Fig. 1. (a-b) ROC curves showing the comparison of the combined model based on the TW1-2 sequence and the clinical features for the training cohort (a) and the validation cohort (b).

AIM To evaluate the safety and efficacy of agitation thrombolysis (AT) combined with catheter-directed thrombolysis (CDT) for the treatment of non-cirrhotic acute portal vein thrombosis (PVT). METHODS Nine patients with non-cirrhotic acute PVT who underwent AT combined with CDT were analyzed retrospectively. Portography was carried out via the transjugular intrahepatic portosystemic (commonly known as TIP) or percutaneous transhepatic (commonly known as PT) route, followed by AT combined with CDT. Complications of the procedure, and the changes in clinical symptoms, hemodynamics of the portal vein and liver function were recorded. Follow-up was scheduled at 1, 3 and 6 mo after treatment, and every 6 mo thereafter, or when the patients developed clinical symptoms related to PVT. Color Doppler ultrasound and contrast-enhanced computed tomography/magnetic resonance imaging were performed during the follow-up period to determine the condition of the portal vein. RESULTS AT combined with CDT was successfully performed. The portal vein was reached via the TIP route in 6 patients, and via the PT route in 3 patients. All clinical symptoms were relieved or disappeared, with the exception of 1 patient who died of intestinal necrosis 9 d after treatment. Significant differences in the changes in portal vein hemodynamics were observed, including the maximum lumen occupancy of PVT, portal vein pressure and flow velocity between pre- and post-treatment (P < 0.05). During the follow-up period, recurrence was observed in 1 patient at 19 mo after the procedure, and the portal vein was patent in the remaining patients. CONCLUSION AT combined with CDT is a safe and effective method for the treatment of non-cirrhotic acute PVT.

In this paper, a whole-arm path planning algorithm for 6-DOF industrial robot based on artificial potential field method is proposed. Multi-station conversion system used for welding robots. First, the environment is monitored by sensors and simplify obstacles and robotic arms. Then transform the Cartesian space obstacle into the C space of the manipulator through the geometric relationship, thus forming the free motion space of the robot arm, which provides conditions for the collision-free path planning of the manipulator. Finally, according to the obstacle repulsive vector summation and target point attraction vector, realize the intuitive rejection reaction, actively avoid the collision of the robot arm, and finally reach the target. We have successfully demonstrated our system on the MA1440 industrial robot.

To understand the endemic situation of soil-borne nematodes and their distribution characteristics, so as to provide the evidence for formulating prevention strategy.According to The Survey Program of Important Human Parasitic Diseases in Fujian Province, the survey spots were determined by the stratified cluster randomly sampling method. The eggs of Ascaris lurmbricoides, hookworm and Trichuris trichiura in feces were detected by Kato-Katz technique; the eggs of Enterobius vermnicularis were checked by rectal swabs using transparent adhesive tape. A questionnaire survey was performed for recording the gender, age, education levels and related epidemiological factors.Altogether 2002 residents in 21 villages of 4 towns were investigated. There were 169 residents infected with soil-borne nematodes (8.44%). The infection rates of hookworm, Trichuris trichiura and Ascaris lumbricoides were 4.35%, 1.70% and 0.15% respectively. The infection rate of Enterobius vermicularis was 13.48% (43/319) in children. The infection rates of soil-borne nematodes were higher in children aged below 7 years and residents aged above 45 years, and the infection rate was higher in the women than in the men. The infection rates 'vere negative correlated with the education levels.The prevalence of soil-borne nematodes has a reduction trend in Yunxiao County. However, the infection rate of hookworm is still high in areas of mainly planting economic crops. The infection rate of Enterobius vermicularis is still high in children, and we should pay more attention to it.