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Menopausal syndrome is a grouping of signs and symptoms associated with menopause. In Ayurveda, menopause is referred to as 'Rajonivrutti' (and menopausal syndrome as Rajonivruttianubandhaja vyadhies). Menopause's long-term risks include osteoporosis, cardiac problems, and Alzheimer's disease. Aims and objective: To study the Pharmacognostic, Phytochemical and HPTLC of Vayasthapana Gana Choorna and Vayasthapana Ghrita. Material and methods: Pharmacognostic, phytochemical and HPTLC of Vayasthapana Gana Choorna and Vayasthapana Ghrita have been carried out as per standard protocol. Result: Vayasthapana Gana Choorna showed the presence of mesocarp, asicular crystals, stone cells, scleroids, brown content, starch grains, colencyma cells, rhomboidal crystals, pitted vessels, parenchyma cells, simple trichome. Phytochemical parameters showed refractive index 1.3660, specific gravity 0.913, acid value 1.285, iodine value 212.1085 and in HPTLC, Methanol extract of Vayasthapana Ghrita at 254nm showed 6 spots and at 366nm 2 spots whereas in methanol extract of Vayasthapana Gana Choorna at 254nm 5 spots and in 366nm 4 spots were present. Conclusion: The applied pharmacognostic and HPTLC method has been shown to be selective, linear, precise and accurate. The method will be useful for quality control of the raw material and pharmaceutical preparations.

Celosia argentea Linn. is a leading leafy vegetable of Nigerian country and India. It is herb, ornamental plant which belongs to family Amaranthaceae also having medicinal use in antidiabetic, anti-inflammatory, antioxidant, anti-bacterial, antiapoptosis etc. For proper methodical evaluation, authentication, macroscopy, microscopy, physicochemical parameters, phytochemical screening and qualitative of seed of C. Argentea has been observed under standard approach. The morphological study showed small black shining spherical, lenticular 3mm in diameter, greyish black in color, slightly aromatic in odour and gritty in touch. Microscopical transverse section of cock’s comb seed showed outer layer of epidermis consisting radially elongated rectangular dark brown color cell, narrow collapsed celled band, outer epidermis of tegmen, followed by parenchyma zone with angular cells of perisperm loaded by starch grains and crystals. Cock’s comb inner cell consists of prismatic crystals and aleurone grains. The unplumbed physicochemical parameters and qualitative screening of seed of cock’s comb are as per standard procedure and useful for future analysis.

Introduction: Shadbindu taila is an Ayurvedic herbo-mineral preparation used in a variety of clinical conditions especially in diseases of upper part of body. This taila is described as exceptionally beneficial for improving the strength of hands. Before a human trial it is essential to evaluate the quality and authenticity of the trial drug, Standardization is needed for assuring quality of any drug and it should be started with the identification and authentication of the drug Materials and method: Pharmacognostical evaluation carried out at Pharmacognosy department, ITRA, Jamnagar, pharmaceutical and HPTLC study were done at Pharmaceutical chemistry department, ITRA, Jamnagar. Microbiological evaluation was carried out at department of Microbiology I.T.R.A, Jamnagar. Results: Organoleptic examination: Colour: Greenish Brown, Odour: Aromatic, Taste: Salty, Touch: Viscous, oily. Pharmaceutical evaluation: specific gravity 0.9177, density 0.8753 Refractive Index 1 .4860, Acid Value 4.042, Saponification Value 132.43, Iodine Value 169.33 HPTLC at 254nm (short wave) showed mainly 6 major spot and at 366 nm (long wave) showed 2 major spots. No organisms isolated in aerobic and fungal culture, in microbiology evaluation. Conclusion: The trial drug is authentic and devoid of any adulteration. All quality control parameters were found to be within the permissible pharmacopeial limits and the stability and shelf life of the trial drug also will be more as per the pharmaceutical parameters.

Erythroxylum moonii Hochr. is a shrub or small tree in family Erythroxylaceae and folklore claims report the use of its leaves in the treatment of helminthiasis. Aim: Hence, present study aims to evaluate the pharmacognostic and analytical characters including HPTLC of its leaves. Methods: E. moonii fresh and powdered leaves were explored for the macroscopic and microscopic features along with their physico-chemical, phytochemical properties and HPTLC following standard procedures. Results: The leaf of E. moonii is simple, alternate, petiolate, stipulate, elliptic and lanceolate with obtusely caudate-acuminate apex, acute base and entire margins. Fresh leaf is light green, slight astringent with characteristic odour and smooth texture. Powdered dry leaves were light green, slight astringent with aromatic odour and coarse, fibrous texture. Microscopic evaluation revealed the presence of simple, bilobed and stellate trichomes (with and without lignification), rosette, rhomboidal, prismatic and cluster crystals, paracytic stomata and starch grains as key characteristics both in fresh leaves and powdered leaves. Obtained values for loss on drying, total ash, acid insoluble ash, pH, water and methanol soluble extractive were 10.44±0.31%, 2.2±0.67%, 0.93±0.06%, 5, 7.63±0.57% and 6.44±0.38% respectively. Qualitative phytochemical analysis suggested the presence of carbohydrates, steroids, glycosides, saponins, alkaloids, tannins and flavonoids in the test sample. HPTLC study revealed 17 and 11 peaks at short (254nm) and long (366nm) ultraviolet consecutively. Conclusion: Obtained results can be used to establish pharmacognostic and analytical standards of leaves of E. moonii which can serve as an important source to determine the quality, purity and strength of the powdered drug.