Search

In the current era of data communication everyone deals with the huge amount of data in form of text, audio, video and different other formats in which everyone want a secure and higher bandwidth channel to transmit and receive so, only the optical channel provides the solution of above said problem. The only difficulty with the existing model that the data from electrical domain first converted in form of light (optical domain) at the transmission end while after receiving the data at the receiver end it will be further converted in form of electrical signal for extracting the message. This type of conversion from one domain to other gives the energy loss. In the current research article, we proposed a model of optical processor which transmit and receive the data without conversion which provides an energy efficient optical technology. By adding reversibility, heat bender can be further reduced. In this manuscript, an arithmetical logic unit has been created, a photonic reversible complete subtractor and an irregular logic portal. SOA-MZI structure is the basic component of the architecture. The method is mainly carried out by the semiconductor Amplifier, using nonlinear properties such as cross-gain modulation and cross-phase modulation. The efficiency deciding factor for the whole system is 21.23 and 53.27 dB in the average extinction ratio. The cost of the arithmetic logic unit optically constructed is 9. [ABSTRACT FROM AUTHOR]

For addressing needs of modern day communication needs, new type of networks are required to be evolved to cater the demand of high data rates. Use of survivable elastic-optical-network (EON) with existing passive-optical-networks (PON) may provide the solution for this. The present work focus on employing EON–PON based wave-length-division multiplexing enabled communication system comprises of 2×5 Gbps for downlink and 2×1 Gbps for uplink over a single-mode-fibre of length 100 km. The results are the evaluated via bit-error-rate analyser, q factor and eye diagrams. [ABSTRACT FROM AUTHOR]

Background: FOXO3, a member of the FOX transcription factor family, is frequently described as being deregulated in cancer. Additionally, notable role of FOXO3 can be easily recognized in the process of ageing and survival. Even though various studies have been done to acknowledge the tumour-suppressive or oncogenic role of FOXO3 in cancer, still there exist a lack of understanding in terms of cancer prognosis and treatment. Therefore, to provide better insight, our study aims to evaluate the role and function of FOXO3 in breast cancer in Indian female patients. We examined the FOXO3 expression levels in breast cancer samples by analyzing mRNA and protein expression along with its clinicopathological parameters. Results: A total of 127 cases of breast cancer with equal normal cases (n=127) were assessed with methylation (MS-PCR), Immunohistochemistry (IHC), mRNA expression using Real-time PCR was analysed and 66.14% cases at mRNA level were found to be downregulated, while 81.10% of cases had little or very little protein expression. Our data state, the promoter hypermethylation of the FOXO3 gene and the downregulated protein expression are significantly correlated (p=0.0004). Additionally, we found a significant correlation between the level of FOXO3 mRNA with ER (p=0.04) and status of lymph node (p=0.01) along with this. Conclusion: Data suggests the prognostic significance and the tumour-suppressive role of FOXO3 in breast cancer cases studied in India. However, there is a need for the extended research targeting FOXO3 to measure its clinical potential and develop well-defined therapeutic strategies. [ABSTRACT FROM AUTHOR]

In this article, first the model of 2×2 reversible logic gate is proposed after then the performance of the proposed designed is evaluated. With the increasing flow of information, data rate is increasing very rapidly. This has resulted in increased amount of heat dissipation from the processing nodes. Generally, electronic processors dissipate heat if the data rate is very high. Hence, this model will be very helpful for solving this problem. Evaluated performance of this model is based on the value of quality factor and extinction ratio. The quality factor and extinction ratio are evaluated under different conditions. The average extinction ratio of the design is 19.58 dB and the average quality factor is 53.03 dB. The optical cost of the proposed circuit is 1. [ABSTRACT FROM AUTHOR]