Search

Your search keyword '"Shuaiying Li"' showing total 5 results
Start Over Author "Shuaiying Li"
5 results on '"Shuaiying Li"'

1. Triple-negative breast cancer cells respond to T cells severely at the alternative splicing layer

Author

Lina Zhao, Xi Yang, Chun Feng, Yue Wang, Qing Wang, Jiahong Pei, Jinting Wu, Shuaiying Li, Honglei Zhang, and Xianbao Cao

Subjects
Alternative splicing, Breast cancer, Cross talk, T cells, Transcriptomic dataset, Translation initiation, Biotechnology, TP248.13-248.65, Biology (General), QH301-705.5
Abstract

Background: Cross talk of tumor–immune cells at the gene expression level has been an area of intense research. However, it is largely unknown at the alternative splicing level which has been found to play important roles in the tumor–immune microenvironment. Results: Here, we re-exploited one transcriptomic dataset to gain insight into tumor–immune interactions from the point of AS level. Our results showed that the AS profiles of triple-negative breast cancer cells co-cultured with activated T cells were significantly changed but not Estrogen receptor positive cells. We further suggested that the alteration in AS profiles in triple-negative breast cancer cells was largely caused by activated T cells rather than paracrine factors from activated T cells. Biological pathway analyses showed that translation initiation and tRNA aminoacylation pathways were most disturbed with T cell treatment. We also established an approach largely based on the AS factor–AS events associations and identified LSM7, an alternative splicing factor, may be responsible for the major altered events. Conclusions: Our study reveals the notable differences of response to T cells among breast cancer types which may facilitate the development or improvement of tumor immunotherapy.How to cite: Zhao L, Yang X, Feng C, et al. Triple-negative breast cancer cells respond to T cells severely at the alternative splicing layer. Electron J Biotechnol 2021;50.https://doi.org/10.1016/j.ejbt.2021.01.001

Published
2021
Full Text
View/download PDF

2. Triple-negative breast cancer cells respond to T cells severely at the alternative splicing layer

Author

Chun Feng, Xianbao Cao, Honglei Zhang, Xi Yang, Jiahong Pei, Lina Zhao, Yue Wang, Shuaiying Li, Jinting Wu, and Qing Wang

Subjects
0106 biological sciences, 0301 basic medicine, medicine.medical_treatment, T cell, lcsh:Biotechnology, Cross talk, T cells, Estrogen receptor, Biology, 01 natural sciences, Applied Microbiology and Biotechnology, Transcriptome, 03 medical and health sciences, Paracrine signalling, Breast cancer, 010608 biotechnology, lcsh:TP248.13-248.65, Translation initiation, medicine, TRNA aminoacylation, lcsh:QH301-705.5, Triple-negative breast cancer, Alternative splicing, Immunotherapy, 030104 developmental biology, medicine.anatomical_structure, lcsh:Biology (General), Transcriptomic dataset, Cancer research, Biotechnology
Abstract

Background Cross talk of tumor–immune cells at the gene expression level has been an area of intense research. However, it is largely unknown at the alternative splicing level which has been found to play important roles in the tumor–immune microenvironment. Results Here, we re-exploited one transcriptomic dataset to gain insight into tumor–immune interactions from the point of AS level. Our results showed that the AS profiles of triple-negative breast cancer cells co-cultured with activated T cells were significantly changed but not Estrogen receptor positive cells. We further suggested that the alteration in AS profiles in triple-negative breast cancer cells was largely caused by activated T cells rather than paracrine factors from activated T cells. Biological pathway analyses showed that translation initiation and tRNA aminoacylation pathways were most disturbed with T cell treatment. We also established an approach largely based on the AS factor–AS events associations and identified LSM7, an alternative splicing factor, may be responsible for the major altered events. Conclusions Our study reveals the notable differences of response to T cells among breast cancer types which may facilitate the development or improvement of tumor immunotherapy. How to cite: Zhao L, Yang X, Feng C, et al. Triple-negative breast cancer cells respond to T cells severely at the alternative splicing layer. Electron J Biotechnol 2021;50. https://doi.org/10.1016/j.ejbt.2021.01.001

Published
2021

4. Search for intermediate resonances and dark gauge bosons in J/ψ→γπ0η′

Author

Kun Zhang, M. Richter, Xinying Song, M. Bertani, B. J. Liu, L. Yang, T. Holtmann, Hai-Bo Li, C. L. Luo, Yuanbo Chen, Marcel Rump, B. Zhong, Ryan Mitchell, Lei Li, Ulrich Wiedner, Andreas Pitka, Viktor Rodin, Qiao Zhou, L. J. Wu, H. J. Lu, Jiawen Zhang, C.-H. Rosner, Gang Chen, Tao Hu, M. X. Luo, D. V. Dedovich, Z. Y. Wang, Qian Liu, H. Q. Zhang, Z. J. Sun, Yajun Mao, J. F. Chang, Y. S. Zhu, I. Garzia, Johannes Bloms, Chengwei Wang, Khurelbaatar Begzsuren, F. Feldbauer, X. K. Zhou, R. Kliemt, Kai Zhu, K. Goetzen, M. Maggiora, Ling Zhao, Sebastian Jaeger, Chang-Zheng Yuan, Y. J. Mo, V. Prasad, S. H. Zhu, Gang Li, Yubin Zhao, Fang Liu, L. L. Wang, X. W. Tang, Zongyuan Wang, Tao Yu, Yongjie Sun, Houbing Jiang, Thomas Lenz, X.S. Li, H. X. Yang, Bo Zheng, Viktor Thorén, Iman Keshk, Feng Liu, J. C. Chen, Sifan Zhang, X. A. Xiong, M. Rolo, Zhenyu Zhang, Xiang Liu, Jacek Biernat, M. Kuemmel, Ming Qi, W. Gradl, Fengcai Ma, Y. Bai, Xuan Zhang, Zhenjun Xiao, A. Mangoni, Xianglei Zhu, Nasser Kalantar-Nayestanaki, Xinyu Shan, Lingyun Liu, I. Denysenko, Yang Gao, X. S. Jiang, P. Weidenkaff, Jie Yu, H. R. Qi, Mengzhen Wang, Hailong Ma, Will Imoehl, Lei Zhao, P. Kiese, Bing Liu, X. Y. Jiang, Xiao Cai, A. A. Zafar, M. J. Chen, Zhonghua Qin, Q. Ouyang, Bin Wang, Huihui Liu, Yi Fang, Jianbin Jiao, I. B. Nikolaev, Bing-Song Zou, Jiaheng Zou, Mathew Glenn Kurth, G. A. Chelkov, Alexander Gilman, J. H. Yin, R. A. Briere, Yunpeng Lu, Tong Liu, Yongzhao Sun, S. S. Fang, O. Bakina, P. R. Li, X. S. Qin, M. Albrecht, T. J. Min, Jingwen Li, Y. B. Liu, H. Y. Sheng, Jens Soeren Lange, Suyu Xiao, Y. T. Gu, Serkant Ali Cetin, Q. An, G. Y. Tang, Q. J. Li, Li Zhou, Z. L. Hou, F. H. Heinsius, Yasemin Schelhaas, Xiaodong Shi, G. S. Huang, K. H. Rashid, Z.Q. Zhang, J. G. Messchendorp, X. R. Zhou, Xingtao Huang, Hao Cai, Rinaldo Baldini Ferroli, Muzaffar Irshad, J. P. Dai, Stephen Lars Olsen, Xiongfei Wang, Xuan Wang, H. S. Chen, Michela Greco, J. W. Zhao, C. B. Zhang, Weishuai Cheng, Huanhuan Liu, Y. Pan, Tobias Weber, D. X. Lin, A. Sarantsev, Klaus Peters, D. H. Wei, Jing Chen, Jing Dong, J. Chai, Meng Wang, Cheng Li, Xin Shi, J. J. Xu, Longzhou Liao, Ming Shao, Y. Z. Sun, Sneha Malde, Thomas Held, Jian Zhuang, Yuehong Xie, J. V. Bennett, Xiaokang Zhou, L. G. Xia, F. Cossio, Fengfei Sui, Jialun Ping, C. F. Liu, Yingchun Zhu, Qingqing Song, Y. J. Zhang, Evelina Gersabeck, Alexey Zhemchugov, M. H. Ye, Xiaoqing Yuan, B. T. Tsednee, Dapeng Jin, H. Y. Zhang, Wanling Chang, Z. Jiao, Fu-Hu Liu, Shuang Han, P. X. Shen, Jingzhi Zhang, K. J. Zhu, Peirong Li, Fabrizio Bianchi, Zhigang Wang, Mathilde Himmelreich, Bingxin Zhang, X. Y. Shen, Yanjia Xiao, Xinchou Lou, Yingrui Hou, Jingwei Zhao, Cui Li, Zhenghao Zhang, L. Y. Dong, Weiping Wang, Yifan Yang, Liang Liu, C. Sowa, Dahua Zhang, Jianbei Liu, M. Y. Dong, S. P. Wen, Xiaoyan Ma, Xinchen Dai, Y. X. Yang, Ning Cao, Duanyou Chen, Y. Nefedov, R. P. Guo, Y. H. Xie, Q. P. Ji, Yun Zeng, S. Gu, Cong-Feng Qiao, Zhibing Li, F. A. Harris, X. B. Ji, L. Koch, A. Khoukaz, Jiada Lu, H. Leithoff, S. Ahmed, J. Min, Kanglin He, F. Nerling, Boxiang Yu, W. Shan, S. Liu, A. Q. Guo, P. L. Wang, Y.Y. Zhang, Francesca De Mori, X. L. Luo, Krishnakumar Ravindran, Aonan Zhu, N. Y.-U. Muchnoi, Y. H. Zheng, B. Kopf, Stefano Lusso, X. S. Kang, Lipeng Zhou, Zhiqing Liu, Y. Q. Wang, Qiang Zhao, S. Nisar, Y. Hu, Pengwei Luo, Kai Liu, Liang Sun, Stefano Spataro, Magnus Wolke, Junfeng Sun, G. Cibinetto, Zhengguo Zhao, X. Q. Hao, Wenjing Zhu, Yong Ban, Rongxing Yang, C. Dong, S. Sosio, J. L. Hu, L. Yan, Haijun Yang, Shuangli Yang, P. Larin, T. Hussain, D. Y. Wang, Hongbang Liu, Junguang Lu, Yangheng Zheng, Y. Guo, J. F. Qiu, X. P. Xu, Z. L. Dou, Dianyu Liu, Q. J. Xu, Yong Ding, G. R. Liao, Yu Lu, J. M. Zhang, Ziyuan Li, Zhaoxia Meng, B. Q. Wang, M. H. Gu, L. H. Wu, Yuqing Wang, W. X. Gong, J. Li, S. Marcello, Xiaofei Cui, Ye Yuan, Dong Liu, L. L. Ma, Y. F. Liang, L. Gong, Libo Guo, O. B. Kolcu, L. Z. Wang, J. Liu, M. Ye, X. H. Mo, L. Fava, Shengsen Sun, P. Patteri, Limin Gu, Ying Fu, Sen Qian, Ronggang Ping, Chuangxin Lin, Wolfgang Kuehn Kühn, Joachim Pettersson, Changjian Tang, Shan Jin, Simon Nakhoul, G. X. Sun, H. H. Li, A. Amoroso, L. Lavezzi, Fang Yan, F. E. Maas, Haiping Peng, Shuaiying Li, Xiaolu Ji, Tianchi Zhao, Meike Kuessner, Sanqiang Qu, Y.N. Gao, Z. A. Zhu, Yan Zhang, Xiaoping Qin, Yao Zhang, Tao Luo, Tianyu Xing, Achim Denig, H. M. Hu, Z. Gao, Alexey Guskov, Tingting Han, Yuekun Heng, F. Y. Li, Y. G. Gao, M. G. Zhao, N. Qin, Sai-Juan Chen, Maxim Alekseev, Longke Li, W. B. Yan, D. Bettoni, Y. F. Long, Yanchu Wang, Guang Zhao, Patrik Adlarson, C. D. Fu, M. N. Achasov, A. Dbeyssi, Ryuta Kiuchi, C. Q. Feng, Rosa Kappert, R. Poling, C. S. Yu, Xiang Pan, Xiaozhong Huang, Wei Xu, Jianping Zheng, Jingzhou Zhao, Alperen Yuncu, X. Y. Gao, Z. Y. Deng, Yanjian Lin, Giulietto Felici, Zhenan Liu, Youhua Yang, S. Pacetti, Shujun Zhao, J. G. Zhang, S. X. Du, H. L. Dai, Igor Boyko, K. Y. Liu, Xuhong Li, Angelo Rivetti, Yi Zhang, Y. T. Liang, Walter Ikegami Andersson, Z. Y. You, Guy Wilkinson, Frederik Weidner, M. Destefanis, J. J. Song, Y. Jin, Ke Li, H. H. Liu, Tord Johansson, Tianjiao Zhang, Z. Wu, R. Farinelli, C. Morales, Andrzej Kupsc, C. F. Redmer, G. F. Cao, Jingzhou Fan, Jiang Zhu, Q. M. Ma, A. Mustafa, Mingming Ma, Yaxing Tan, X. N. Li, D. M. Li, M. Fritsch, Xuyang Liu, Yu Zhang, C. P. Shen, Xiaolong Wang, J. Zhang, M. Kavatsyuk, Y. D. Wang, H. Muramatsu, Hongwei Wen, J. W. Zhang, M. Pelizaeus, Wei Li, B. X. Zhang, Michael Papenbrock, I. Uman, C. Schnier, Lei Zhang, Tianyu Qi, B. C. Ke, Nils Huesken, Stephan Maldaner, M. Ablikim, G. Rong, Z. P. Mao, H. Liang, W. D. Li, Xinxin Ma, A. Calcaterra, Ke Wang, Ke Liu, Q. A. Malik, G. Mezzadri, W. C. Yan, Guofa Xu, Y. M. Ma, J. Fang, Zhe Ning, X. B. Ma, J. Libby, Xiao-Rui Lyu, Ilaria Balossino, K. Schoenning, and Niklaus Berger

Subjects
Physics, Gauge boson, Particle physics, 010308 nuclear & particles physics, Electron–positron annihilation, 0103 physical sciences, Pi, CP violation, Gauge (firearms), 010306 general physics, 01 natural sciences, Prime (order theory)
Abstract

We report on an analysis of the decay J/ψ→γπ0η′ using a sample of (1310.6±7.0)×106J/ψ events collected with the BESIII detector. We search for the CP-violating process ηc→π0η′ and a dark gauge boso ...

Published
2020

5. Hadronic charm decays at BESIII

Author

Shuaiying Li

Subjects
Physics, Particle physics, Electron–positron annihilation, High Energy Physics::Phenomenology, Hadron, Electron, law.invention, Positron, law, High Energy Physics::Experiment, Charm (quantum number), Open charm, Nuclear Experiment, Collider
Abstract

The BESIII experiment at the Beijing Electron Positron Collider (BEPCII) has accumulated the world’s largest samples of $e+e−$ collisions in the tau-charm region. Based on the threshold open charm data samples $ofD(s)andΛ+c$, we can study the hadronic charm decays under a uniquely clean background. Many important results have been achieved with much-improved precision or for the first time. In this paper, we will review some recent results on the hadronic charm decays.Finally, a summary will be given.

Published
2019

Catalog

Books, media, physical & digital resources
See catalog results