228 results on '"Shone, Clifford C."'
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2. The structure of the S-layer of Clostridium difficile
3. The thioredoxin reductase – Thioredoxin redox system cleaves the interchain disulphide bond of botulinum neurotoxins on the cytosolic surface of synaptic vesicles
4. The molecular structure of the glycoside hydrolase domain of Cwp19 from Clostridium difficile
5. Cwp2 from Clostridium difficile exhibits an extended three domain fold and cell adhesion in vitro
6. Long-Term Effects of Botulinum Type A Neurotoxin on the Release of Noradrenaline from PC12 Cells
7. Inhibition of botulinum neurotoxins interchain disulfide bond reduction prevents the peripheral neuroparalysis of botulism
8. Confocal Endomicroscopy of Neuromuscular Junctions Stained with Physiologically Inert Protein Fragments of Tetanus Toxin
9. Molecular features of the sortase enzyme family
10. Proliferative T Cell Response to Botulinum Toxin Type A in Mice
11. Re-engineering the target specificity of clostridial neurotoxins - a route to novel therapeutics
12. A Novel, Orally Delivered Antibody Therapy and Its Potential to Prevent Clostridioides difficile Infection in Pre-clinical Models
13. A family of killer toxins: Exploring the mechanism of ADP-ribosylating toxins
14. Botulinum neurotoxin B inhibits insulin-stimulated glucose uptake into 3T3-L1 adipocytes and cleaves cellubrevin unlike type A toxin which failed to proteolyze the SNAP-23 present
15. Botulinum neurotoxin C1 cleaves both syntaxin and SNAP-25 in intact and permeabilized chromaffin cells: correlation with its blockade of catecholamine release
16. Differences in the protease activities of tetanus and botulinum B toxins revealed by the cleavage of vesicle-associated membrane protein and various sized fragments
17. Genomes of Escherichia coli bacteraemia isolates originating from urinary tract foci contain more virulence-associated genes than those from non-urinary foci and neutropaenic hosts
18. Purification and Radiolabeling of Clostridium botulinum Type F Neurotoxin
19. Contributors to Volume 8
20. Modification of surface histidine residues abolishes the cytotoxic activity of Clostridium difficile toxin A
21. High prevalence of subclass-specific binding and neutralizing antibodies against Clostridium difficile toxins in adult cystic fibrosis sera: possible mode of immunoprotection against symptomatic C. difficile infection
22. The structure of the cysteine protease and lectin-like domains of Cwp84, a surface layer-associated protein from Clostridium difficile
23. The molecular structure of the glycoside hydrolase domain of Cwp19 fromClostridium difficile
24. Toxigenic Clostridia
25. Functional significance of active site residues in the enzymatic component of the Clostridium difficile binary toxin
26. The thioredoxin reductase-thioredoxin system is involved in the entry of tetanus and botulinum neurotoxins in the cytosol of nerve terminals
27. Erratum to “Inhibition of botulinum neurotoxins interchain disulfide bond reduction prevents the peripheral neuroparalysis of botulism” [Biochem. Pharmacol. 98 (2015) 522–530]
28. A Novel Inhibitor Prevents the Peripheral Neuroparalysis of Botulinum Neurotoxins
29. Profiling Humoral Immune Responses to Clostridium difficile-Specific Antigens by Protein Microarray Analysis
30. Structure and function of a Clostridium difficile sortase enzyme
31. Cwp84, aClostridium difficilecysteine protease, exhibits conformational flexibility in the absence of its propeptide
32. 188. EGA prevents the neuronal toxicity of BoNT/A and BoNT/B
33. CAROTENOPROTEINS
34. Botulinum toxin: from menace to medicine
35. Thioredoxin and Its Reductase Are Present on Synaptic Vesicles, and Their Inhibition Prevents the Paralysis Induced by Botulinum Neurotoxins
36. The structure of the cysteine protease and lectin-like domains of Cwp84, a surface layer-associated protein fromClostridium difficile
37. Time course and temperature dependence of the membrane translocation of tetanus and botulinum neurotoxins C and D in neurons
38. SNARE motif and neurotoxins
39. The thioredoxin reductase-thioredoxin system is involved in the entry of tetanus and botulinum neurotoxins in the cytosol of nerve terminals
40. Functional significance of active site residues in the enzymatic component of the Clostridium difficilebinary toxin
41. Double anchorage to the membrane and intact inter-chain disulfide bond are required for the low pH induced entry of tetanus and botulinum neurotoxins into neurons
42. Expression, purification, crystallization and preliminary crystallographic analysis of a putativeClostridium difficilesurface protein Cwp19
43. Super toxins from a super bug: structure and function of Clostridium difficile toxins
44. Expression, purification and cell cytotoxicity of actin-modifying binary toxin from Clostridium difficile
45. Cwp84, a Surface-associated Cysteine Protease, Plays a Role in the Maturation of the Surface Layer of Clostridium difficile
46. Structural Basis for Substrate Recognition in the Enzymatic Component of ADP-ribosyltransferase Toxin CDTa from Clostridium difficile
47. Cwp84, a Clostridium difficile cysteine protease, exhibits conformational flexibility in the absence of its propeptide.
48. Preparation of specifically activatable endopeptidase derivatives of Clostridium botulinum toxins type A, B, and C and their applications
49. C3 exoenzyme fromClostridium botulinum: structure of a tetragonal crystal form and a reassessment of NAD-induced flexure
50. Retargeted clostridial endopeptidases: Inhibition of nociceptive neurotransmitter release in vitro, and antinociceptive activity in in vivo models of pain
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