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Vaccination has led to significant dismantling of infectious diseases worldwide. Since the dawn of the SARS-CoV-2 pandemic, there has been increased popularity in the usage and study of the mRNA vaccine platform. Here, we highlight fundamental knowledge on mRNA vaccine pharmacology, followed by the immunity conferred by innate sensing and adaptive responses resulting from exposure to the mRNA vaccine construct and encapsulation materials. A better understanding of these immune mechanisms will shed light on further improvements in mRNA vaccine design, aiming to improve efficiency and optimize immune responses upon inoculation. [ABSTRACT FROM AUTHOR]

The poultry industry plays a crucial role in global food production, with chickens being the most widely consumed as a rich protein source. However, infectious diseases pose significant threats to poultry health, underscoring the need for rapid and accurate detection to enable timely intervention. In recent years, biosensors have emerged as essential tools to facilitate routine surveillance on poultry farms and rapid screening at slaughterhouses. These devices provide producers and veterinarians with timely information, thereby promoting proactive disease management. Biosensors have been miniaturized, and portable platforms allow for on-site testing, thereby enhancing biosecurity measures and bolstering disease surveillance networks throughout the poultry supply chain. Consequently, biosensors represent a transformative advancement in poultry disease management, offering rapid and precise detection capabilities that are vital for safeguarding poultry health and ensuring sustainable production systems. This section offers an overview of biosensors and their applications in detecting poultry diseases, with a particular emphasis on enteric pathogens.