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大建中湯が奏効した難治性下痢症の一例を報告した。症例は60歳の女性。水様下痢が持続し，真武湯，甘草瀉心湯，四逆湯などを投与したが改善しなかった。腹痛や腹部の冷え，蠕動不穏等の典型的な大建中湯証の症候が備わっていないにもかかわらず，大建中湯に転方したところ下痢は改善した。大建中湯は便秘あるいは下痢にかかわらず，陰証虚証で，腸内に水とガスが停滞した病態に適応となる可能性がある。

Novel functionalized poly(tetramethyl-1,4-silphenylenesiloxane) with pendant hydroxyl groups, i.e., poly[2,5-bis(2-hydroxyethoxy)-tetramethyl-1,4-silphenylenesiloxane] (P1), was synthesized and characterized by differential scanning calorimetry (DSC), thermogravimetry (TG), and X-ray diffraction analysis. P1 was obtained via catalytic deprotective-hydrogenation of poly[2,5-bis(2-benzyloxyethoxy)-tetramethyl-1,4-silphenylenesiloxane] (PreP1), which had been obtained by catalytic polycondensation of 2,5-bis(2-benzyloxyethoxy)-1,4-bis(dimethylhydroxysilyl)benzene (M1) in benzene. P1 was revealed to be an amorphous polymer as deduced from DSC as well as X-ray diffraction measurement, and soluble in highly polar solvents as ethanol and methanol in which poly(tetramethyl-1,4-silphenylenesiloxane) (1,4-PTMPS) is insoluble. The glass transition temperature (Tg) of P1 was determined to be 73 °C from DSC, which was much higher than that of 1,4-PTMPS (−20 °C), indicating that the intermolecular and/or intramolecular hydrogen bondings based on hydroxyl groups restricted the mobility of the main chain. The temperature at 5% weight loss (Td5) of P1 (290 °C) determined by TG was lower than that of 1,4-PTMPS, indicating that the oxyethylene and/or alcoholic-hydroxyl moieties decline the thermostability; however, the obtained P1 would promise to be a new reactive-polymer with hydroxyl moieties to develop new functional materials.