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7. Abstract 16897: The Association of Lipoprotein(a) With Major Adverse Cardiovascular Events Among Individuals With and Without Baseline Atherosclerotic Cardiovascular Disease: The Mass General Brigham Lp(a) Registry

Author

Berman, Adam N, Biery, David, Besser, Stephanie, Singh, Avinainder, Weber, Brittany N, Huck, Daniel M, Divakaran, Sanjay, Hainer, Jon, Shiyovich, Arthur, Kaur, Gurleen, Blaha, Michael J, Cannon, Christopher P, Plutzky, Jorge, Januzzi, James L, Booth, John N, Lopez, J. A, Kent, Shia, Nasir, Khurram, Di Carli, Marcelo, Bhatt, Deepak L, and Blankstein, Ron

Published
2023
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8. Abstract 16773: The Association of Lp(a) and Standard Modifiable Cardiovascular Risk Factors (SMuRFs) With Incident Myocardial Infarction: The Mass General Brigham Lp(a) Registry

Author

Shiyovich, Arthur, Berman, Adam N, Besser, Stephanie A, Biery, David W, Kaur, Gurleen, Divakaran, Sanjay, Singh, Avinainder, Huck, Daniel M, Weber, Brittany N, Plutzky, Jorge, Di Carli, Marcelo, Nasir, Khurram, Cannon, Christopher P, Januzzi, James L, Bhatt, Deepak L, and Blankstein, Ron

Published
2023
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16. Characteristics of aortic root and vascular anatomy in bicuspid versus tricuspid aortic valve anatomy in patients referred for TAVR

Author

Schamroth Pravda, Nili, primary, Plakht, Ygal, additional, Shiyovich, Arthur, additional, Aviv, Yaron, additional, Wiessman, Maya, additional, Shafir, Gideon, additional, Assa, Hana Vaknin, additional, Codner, Pablo, additional, Assali, Abid, additional, Segev, Amit, additional, Barabash, Israel, additional, Lessick, Jonathan, additional, Kerner, Arthur, additional, Goitein, Orly, additional, Brodov, Yafim, additional, Kornowski, Ran, additional, and Hamdan, Ashraf, additional

Published
2024
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17. Increased Rate of New-onset Left Bundle Branch Block in Patients With Bicuspid Aortic Stenosis Undergoing Transcatheter Aortic Valve Implantation (From a National Registry)

Author

Shiyovich, Arthur, Kornowski, Ran, Plakht, Ygal, Aviv, Yaron, Assa, Hana Vaknin, Assali, Abid, Bental, Tamir, Lessick, Jonathan, Kerner, Arthur, Segev, Amit, Barabash, Israel M., Goitein, Orly, Brodov, Yafim, Massalha, Eias, Finkelstein, Ariel, Perlman, Gidon Y., and Hamdan, Ashraf

Published
2021
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19. Improvement in Echocardiographic Indexes of Systolic Heart Failure Post-Kidney Transplantation: A Retrospective Analysis.

Author

Skalsky, Keren, Perl, Leor, Rozen Zvi, Benaya, Atamna, Mohamad, Kornowski, Ran, Nesher, Eviatar, Rahamimov, Ruth, Ben Gal, Tuvia, Shapira, Yaron, Shiyovich, Arthur, and Steinmetz, Tali

Subjects
CARDIO-renal syndrome, CHRONIC kidney failure, KIDNEY transplantation, CARDIOVASCULAR diseases risk factors, HEART transplantation, HEART failure
Abstract

Introduction: End-stage renal disease is a major risk factor for cardiovascular morbidity and mortality, which can be partially eliminated by kidney transplantation. Systolic heart failure might be considered contraindication for kidney transplant, although some patients demonstrate myocardial recovery post-transplant. We aimed to identify and characterize the phenomenon of reverse myocardial remodeling in kidney transplanted patients. Methods: The study is a retrospective cohort of patients undergoing kidney transplants between 2016 and 2019 (n = 604) at Rabin Medical Center. Patients were assessed according to availability of two echocardiographic examinations: pre- and post-kidney transplant. The change in estimated ejection fraction (EF) and possible predictors of myocardial recovery were examined. Results: Data of 293 patients was available for the final analysis. Eighty-one (28%) patients had a LVEF improvement equal to or above 5%, whereas 36 (12%) patients had a LVEF improvement of 10% or more post-transplantation. Twenty-five patients (8.5%) had moderate or severe systolic heart failure with LVEF reduced to 40% or less at baseline. 13 of them (52%) had a LVEF improvement of ≥5%, and 10 patients (40%) had an improvement of ≥10% in their EF. Cox regression analyses identified female gender as the only independent variable associated with LVEF improvement of at least 10%. Conclusion: Renal transplantation might lead to improved LV systolic function in some patients. [ABSTRACT FROM AUTHOR]

Published
2024
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20. Recovery from Acute Kidney Injury and Long-Term Prognosis following Acute Myocardial Infarction.

Author

Skalsky, Keren, Shiyovich, Arthur, Shechter, Alon, Gilutz, Harel, and Plakht, Ygal

Subjects
MYOCARDIAL infarction, ACUTE kidney failure, RECEIVER operating characteristic curves, MORTALITY, PROGNOSIS
Abstract

We investigated the recovery pattern from acute kidney injury (AKI) following acute myocardial infarction (AMI) and its association with long-term mortality. The retrospective study included AMI patients (2002–2027), who developed AKI during hospitalization. Creatinine (Cr) measurements were collected and categorized into 24 h timeframes up to 7 days from AKI diagnosis. The following groups of recovery patterns were defined: rapid (24–48 h)/no rapid and early (72–144 h)/no early recovery. Specific cut-off points for recovery at each AKI stage and timeframe were determined through receiver operating characteristic (ROC) curves. The probability of long-term (up to 10 years) mortality as a post-AKI recovery was investigated using a survival approach. Out of 17,610 AMI patients, 1069 developed AKI. For stage 1 AKI, patients with a Cr ratio <1.5 at 24 h and/or <1.45 at 48 h were defined as 'rapid recovery'; for stages 2–3 AKI, a Cr ratio <2.5 at 96 h was defined as 'early recovery'. Mortality risk in stage 1 AKI was higher among the non-rapidly recovered: AdjHR = 1.407; 95% CI: 1.086–1.824; p = 0.010. Among stages 2–3 AKI patients, the risk for long-term mortality was higher among patients who did not recover in the early period: AdjHR = 1.742; 95% CI: 1.085–2.797; p = 0.022. The absence of rapid recovery in stage 1 AKI and lack of early recovery in stages 2–3 AKI are associated with higher long-term mortality. [ABSTRACT FROM AUTHOR]

Published
2024
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21. Association of Lipoprotein (a) and Standard Modifiable Cardiovascular Risk Factors With Incident Myocardial Infarction: The Mass General Brigham Lp(a) Registry.

Author

Shiyovich, Arthur, Berman, Adam N., Besser, Stephanie A., Biery, David W., Kaur, Gurleen, Divakaran, Sanjay, Singh, Avinainder, Huck, Daniel M., Weber, Brittany, Plutzky, Jorge, Di Carli, Marcelo F., Nasir, Khurram, Cannon, Christopher, Januzzi, James L., Bhatt, Deepak L., and Blankstein, Ron

Published
2024
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23. Interventricular septal thickness on cardiac computed tomography as a novel risk factor for conduction disturbances in patients undergoing transcatheter aortic valve replacement.

Author

Pravda, Nili Schamroth, Shaleve, Yonatan, Plakht, Ygal, Shafir, Gideon, Grinberg, Tzil, Wiessman, Maya, Aviv, Yaron, Assa, Hana Vaknin, Codner, Pablo, Golovchiner, Gregory, Barsheshet, Alon, Kornowski, Ran, Shiyovich, Arthur, and Hamdan, Ashraf

Abstract

Aims We examined whether thickness of the basal muscular interventricular septum (IVS), as measured by pre-procedural computed tomography (CT), could be used to identify the risk of conduction disturbances following transcatheter aortic valve replacement (TAVR). The IVS is a pivotal region of the electrical conduction system of the heart where the atrioventricular conduction axis is located. Methods and results Included were 78 patients with severe aortic stenosis who underwent CT imaging prior to TAVR. The thickness of muscular IVS was measured in the coronal view, in systolic phases, at 1, 2, 5, and 10 mm below the membranous septum (MS). The primary endpoint was a composite of conduction disturbance following TAVR. Conduction disturbances occurred in 24 out of 78 patients (30.8%). Those with conduction disturbances were significantly more likely to have a thinner IVS than those without conduction disturbances at every measured IVS level (2.98 ± 0.52 mm vs. 3.38 ± 0.52 mm, 4.10 ± 1.02 mm vs. 4.65 ± 0.78 mm, 6.11 ± 1.12 mm vs. 6.88 ± 1.03 mm, and 9.72 ± 1.95 mm vs. 10.70 ± 1.55 mm for 1, 2, 5 and 10 mm below MS, respectively, P < 0.05 for all). Multivariable logistic regression analysis showed that pre-procedural IVS thickness (<4 mm at 2 mm below the MS) was a significant independent predictor of post-procedural conduction disturbance (adjOR 7.387, 95% CI: 2.003–27.244, P = 0.003). Conclusion Pre-procedural CT assessment of basal IVS thickness is a novel predictive marker for the risk of conduction disturbances following TAVR. The IVS thickness potentially acts as an anatomical barrier protecting the underlying conduction system from mechanical compression during TAVR. [ABSTRACT FROM AUTHOR]

Published
2024
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29. Cardiovascular outcomes in patients with coronary artery disease and elevated lipoprotein(a): implications for the OCEAN(a)-outcomes trial population

Author

Shiyovich, Arthur, primary, Berman, Adam N, additional, Besser, Stephanie A, additional, Biery, David W, additional, Huck, Daniel M, additional, Weber, Brittany, additional, Cannon, Christopher, additional, Januzzi, James L, additional, Booth, John N, additional, Nasir, Khurram, additional, Di Carli, Marcelo F, additional, López, J Antonio G, additional, Kent, Shia T, additional, Bhatt, Deepak L, additional, and Blankstein, Ron, additional

Published
2023
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36. The short and long‐term characteristics and outcomes of patients with grade 1 myocardial uptake on cardiac scintigraphy

Author

Itzhaki Ben Zadok, Osnat, primary, Ruhrman‐Sahar, Noa, additional, Mats, Israel, additional, Vaxman, Iuliana, additional, Shiyovich, Arthur, additional, Aviv, Yaron, additional, Vaturi, Mordehai, additional, Wiessman, Maya, additional, Shochat, Tzippy, additional, Kandinov, Irit, additional, Kornowski, Ran, additional, and Hamdan, Ashraf, additional

Published
2023
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41. List of Contributors

Author

Abela, George S., primary, Abouzaki, Nayef A., additional, Ahmadjee, Abdulmohsin, additional, Al-Salaimeh, Ayman, additional, Aladdin, Mohammed, additional, Albuquerque, Felipe N., additional, Ariëns, Robert A.S., additional, Asher, Elad, additional, Azadani, Ali N., additional, Badimon, Lina, additional, Baker, Stephen R., additional, Banerjee, Subhash, additional, Bannish, Brittany E., additional, Bavry, Anthony A., additional, Beinart, Roy, additional, Ben-Aicha, Soumaya, additional, Brilakis, Emmanouil S., additional, Brosnan, Rhoda B., additional, Chatterjee, Arka, additional, Cioni, Gabriele, additional, Clapp, Brian, additional, Danenberg, Haim D., additional, de Jaegere, P.P.T., additional, de Marchena, Eduardo, additional, De Silva, Kalpa, additional, Dvir, Danny, additional, Elgendy, Islam Y., additional, Eliaz, Ran, additional, Ferro, Albert, additional, Finn, Aloke V., additional, Fishman, Joel E., additional, Fuksbrumer, Moshe S., additional, Ghodsizad, Ali, additional, Glikson, Michael, additional, Goldstein, Larry B., additional, Gorla, Sudheer, additional, Grupper, Avishai, additional, Guttmann, Oliver P., additional, Harris, Lindsay, additional, Havlichek, Daniel, additional, Hawk, Christopher, additional, Henry, Timothy, additional, Hirschl, David A., additional, Hoffman, Ron, additional, Humphrey, Holly, additional, Jinnouchi, Hiroyuki, additional, Jones, Gregory K., additional, Jones, Daniel A., additional, Jovin, Ion S., additional, Karacsonyi, Judit, additional, Kelley, Michael A., additional, Kereiakes, Dean J., additional, Harrison, J. Kevin, additional, Kornowski, Ran, additional, Kramer, Mordechai R., additional, Lamichhane, Madhab, additional, Landi, Antonio, additional, Layne, Kerry, additional, Leesar, Massoud A., additional, Leiderman, Karin, additional, Lewis, Neil P., additional, Ligthart, Jurgen, additional, Lishner, Michael, additional, Macias, Alejandro E., additional, Magarakis, Michael, additional, Mahmoud, Ahmed N., additional, Mahtta, Dhruv, additional, Mankad, Anit, additional, Martinez, Claudia A., additional, Mendirichaga, Rodrigo, additional, Michalets, Elizabeth, additional, Michalove, Benjamin, additional, Mitra, Subhashis, additional, Nagalla, Srikanth, additional, Napodano, Massimo, additional, O’Kane, Peter, additional, Onishi, Takayuki, additional, Onishi, Yuko, additional, Orlev, Amir, additional, Palmisano, Ada M., additional, Passacquale, Gabriella, additional, Peek, Brian T., additional, Perera, Divaka, additional, Pineda, Andres M., additional, Rao, Sunil V., additional, Rathod, Krishnaraj S., additional, Regar, Evelyn, additional, Ren, Claire, additional, Rosenschein, Uri, additional, Ryan, Matthew J., additional, Salehi, Negar, additional, Salerno, Tomas A., additional, Sandhu, Satinder K., additional, Sarembock, Ian J., additional, Sawey, Edward J., additional, Segev, Amit, additional, Shammas, Nicolas W., additional, Shen, Yu-Min, additional, Shiyovich, Arthur, additional, Shreenivas, Satya S., additional, Smith, James, additional, Smith, Elliot J., additional, Stumpf, Emily, additional, Topaz, Allyne, additional, Ungi, Imre, additional, Unterman, Avraham, additional, Vilahur, Gemma, additional, Virmani, Renu, additional, Watts, Thomas E., additional, Wood, Emily E., additional, Younis, Arwa, additional, and Zampolin, Richard L., additional

Published
2018
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43. Albumin as a Prognostic Marker for Atrial Fibrillation Recurrence following Cryoballoon Ablation of Pulmonary Venous

Author

Schamroth Pravda, Nili, primary, Golovchiner, Gregory, additional, Goldenberg, Gustavo, additional, Plakht, Ygal, additional, Wiessman, Maya, additional, Tal, Shir, additional, Barsheshet, Alon, additional, Kadmon, Ehud, additional, Erez, Aharon, additional, Skalsky, Keren, additional, Grinberg, Tzlil, additional, Nardi Agmon, Inbar, additional, Aviv, Yaron, additional, Kornowski, Ran, additional, Shiyovich, Arthur, additional, and Hamdan, Ashraf, additional

Published
2022
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45. Myocarditis after BNT162b2 Vaccination in Israeli Adolescents

Author

Witberg, Guy, primary, Magen, Ori, additional, Hoss, Sara, additional, Talmor-Barkan, Yeela, additional, Richter, Ilan, additional, Wiessman, Maya, additional, Aviv, Yaron, additional, Grinberg, Tzlil, additional, Shiyovich, Arthur, additional, Schamroth-Pravda, Nili, additional, Auster, Oren, additional, Dagan, Noa, additional, Birk, Einat, additional, Balicer, Ran, additional, and Kornowski, Ran, additional

Published
2022
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