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1. Contents Vol. 79, 2013

Author

Dan Nemet, Antonella Puglianiello, Andreas Hungele, Verónica Mericq, C.F. Munns, Danilo Fintini, C. Bridge, Jan de Laffolie, Michaela F. Hartmann, Débora Macedo Cabral, Alon Eliakim, Elena Inzaghi, Holger Haberland, Carolina Sepúlveda, Claudia Brufani, Berthold P. Hauffa, Shira Oren, Cinthya Urquidi, J. Ault, Reinhard W. Holl, D.O. Sillence, Stefano Cianfarani, Enrica Pittaluga, Annalisa Deodati, Jörg Fussenegger, Laurie E. Cohen, Daniela Germani, Alejandra Avila, Stefan A. Wudy, Burak Salgin, Chuan Shen, Eliana Hechter, M. McQuade, Satz Mengensatzproduktion, Ari J. Wassner, Thomas Meissner, Ulrich Brand, Michal Pantanowitz, Marco Cappa, Rodrigo José Custódio, Alice Liguori, M.B. Alcausin, V. Pacey, Klaus-Peter Zimmer, Peter Beyer, Martin Borkenstein, Druck Reinhardt Druck Basel, Fernando Carrasco, Zhang Hui Tang, Sonir Roberto Rauber Antonini, Kang Min Wu, Carlos Eduardo Martinelli, Claudia Boettcher, Fabrizio Barbetti, Andrew Dauber, J. Briody, R.H.H. Engelbert, Tao Yu, Carlos Antonio Bruno da Silva, and Germán Iñiguez

Subjects
Endocrinology, Endocrinology, Diabetes and Metabolism, Pediatrics, Perinatology and Child Health, Physiology, Biology
Published
2013
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2. Effects of a Multidisciplinary Childhood Obesity Treatment Intervention on Adipocytokines, Inflammatory and Growth Mediators

Author

Dan Nemet, Michal Pantanowitz, Alon Eliakim, and Shira Oren

Subjects
Leptin, Male, Pediatric Obesity, medicine.medical_specialty, Adolescent, Diet, Reducing, Endocrinology, Diabetes and Metabolism, Physical activity, Adipokine, Childhood obesity, Body Mass Index, Endocrinology, Adipokines, Multidisciplinary approach, Intervention (counseling), medicine, Humans, Child, Exercise, Adiponectin, Interleukin-6, business.industry, Body Weight, Anthropometry, medicine.disease, Obesity, C-Reactive Protein, Physical Fitness, Pediatrics, Perinatology and Child Health, Physical therapy, Intercellular Signaling Peptides and Proteins, Female, Inflammation Mediators, Insulin Resistance, business
Abstract

Background/Aims: To examine the effects of a 3-month multidisciplinary intervention on anthropometric measures, physical activity patterns and fitness, inflammatory cytokines, adipocytokines, and growth mediators in obese children. Methods: 21 obese subjects completed the 3-month intervention and were compared with 20 age-, gender- and maturity-matched controls. Subjects underwent anthropometric measurements (weight, height, BMI percentile and waist circumference), blood tests (IL-6, CRP, leptin, adiponectin, insulin, IGF-I and glucose), a progressive treadmill exercise test to evaluate fitness, and habitual activity assessment before and after the intervention. Results: The intervention led to a significant change of differences in body weight (-1.3 ± 4.1 vs. 2.5 ± 3.3 kg), BMI percentile (-0.96 ± 1.29 vs. 0.19 ± 0.8), waist circumference (-2.1 ± 2.7 vs. 2.9 ± 3.0 cm) and running time (149.9 ± 86.3 vs. -8.2 ± 88.0 s) in the intervention compared to control. There was a significant increase in leisure-time physical activity (Godin questionnaire, 29.04 ± 6.8 vs. -1.3 ± 9.2) and a decrease in sedentary activity (-1.4 ± 0.73 vs. 0.02 ± 0.62 h/day) in the intervention compared to control. Significant change differences in adiponectin (2,308 ± 1,640 vs. -801 ± 465 ng/ml), IGF-I (33.8 ± 37.8 vs. -1.0 ± 36.2 ng/ml), CRP (-0.06 ± 0.29 vs. 0.5 ± 0.86 mg/dl) and HOMA-IR (-0.15 ± 0.57 vs. 0.55 ± 0.84) were found in the intervention group compared to control. Conclusions: Our results highlight the short-term beneficial effects of a childhood obesity multidisciplinary intervention on anthropometrics, habitual activity, fitness, inflammatory and metabolic measures. The longer-term effects of these changes on obesity-associated metabolic risks are yet to be determined.

Published
2013
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3. Subject Index Vol. 79, 2013

Author

Ari J. Wassner, Sonir Roberto Rauber Antonini, Thomas Meissner, Jan de Laffolie, Claudia Boettcher, Reinhard W. Holl, Michaela F. Hartmann, Fernando Carrasco, Kang Min Wu, Peter Beyer, Ulrich Brand, Antonella Puglianiello, Jörg Fussenegger, Carlos Eduardo Martinelli, Verónica Mericq, Shira Oren, Laurie E. Cohen, Stefan A. Wudy, C.F. Munns, Dan Nemet, Rodrigo José Custódio, Druck Reinhardt Druck Basel, Eliana Hechter, Débora Macedo Cabral, Alice Liguori, Berthold P. Hauffa, Daniela Germani, Andreas Hungele, Carolina Sepúlveda, Stefano Cianfarani, Enrica Pittaluga, Annalisa Deodati, Michal Pantanowitz, Claudia Brufani, Alejandra Avila, Carlos Antonio Bruno da Silva, Holger Haberland, C. Bridge, M.B. Alcausin, Satz Mengensatzproduktion, J. Ault, Alon Eliakim, Fabrizio Barbetti, Andrew Dauber, Burak Salgin, Martin Borkenstein, J. Briody, D.O. Sillence, Cinthya Urquidi, R.H.H. Engelbert, Elena Inzaghi, Chuan Shen, Danilo Fintini, Klaus-Peter Zimmer, Marco Cappa, V. Pacey, Zhang Hui Tang, M. McQuade, Germán Iñiguez, and Tao Yu

Subjects
Gerontology, Endocrinology, Index (economics), business.industry, Endocrinology, Diabetes and Metabolism, Pediatrics, Perinatology and Child Health, Physiology, Medicine, Subject (documents), business
Published
2013
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