Search

Your search keyword '"Shin, Soo K."' showing total 9 results
Start Over Author "Shin, Soo K."
9 results on '"Shin, Soo K."'

1. Tanshinone IIA-loaded nanoparticles and neural stem cell combination therapy improves gut homeostasis and recovery in a pig ischemic stroke model

Author

Jeon, Julie H., Kaiser, Erin E., Waters, Elizabeth S., Yang, Xueyuan, Lourenco, Jeferson M., Fagan, Madison M., Scheulin, Kelly M., Sneed, Sydney E., Shin, Soo K., Kinder, Holly A., Kumar, Anil, Platt, Simon R., Ahn, Jeongyoun, Duberstein, Kylee J., Rothrock, Jr., Michael J., Callaway, Todd R., Xie, Jin, West, Franklin D., and Park, Hea Jin

Published
2023
Full Text
View/download PDF

2. Tanshinone IIA-Loaded Nanoparticle and Neural Stem Cell Therapy Enhances Recovery in a Pig Ischemic Stroke Model

Author

Kaiser, Erin E, primary, Waters, Elizabeth S, additional, Yang, Xueyuan, additional, Fagan, Madison M, additional, Scheulin, Kelly M, additional, Sneed, Sydney E, additional, Cheek, Savannah R, additional, Jeon, Julie Heejin, additional, Shin, Soo K, additional, Kinder, Holly A, additional, Kumar, Anil, additional, Platt, Simon R, additional, Duberstein, Kylee J, additional, Park, Hea Jin, additional, Xie, Jin, additional, and West, Franklin D, additional

Published
2022
Full Text
View/download PDF

3. Abstract WMP119: Tanshinone IIa-loaded Nanoparticles And Induced Pluripotent Stem Cell-derived Neural Stem Cell Therapies Enhance Recovery In A Translational Pig Ischemic Stroke Model

Author

Kaiser, Erin E, primary, Waters, Elizabeth S, additional, Yang, Xueyuan, additional, Fagan, Madison M, additional, Scheulin, Kelly M, additional, Sneed, Sydney E, additional, Jeon, Julie H, additional, Shin, Soo K, additional, Kinder, Holly A, additional, Kumar, Anil, additional, Platt, Simon R, additional, Duberstein, Kylee J, additional, Park, Hea Jin, additional, Xie, Jin, additional, and West, Franklin D, additional

Published
2022
Full Text
View/download PDF

4. Intracisternal administration of tanshinone IIA-loaded nanoparticles leads to reduced tissue injury and functional deficits in a porcine model of ischemic stroke

Author

Waters, Elizabeth S., primary, Kaiser, Erin E., additional, Yang, Xueyuan, additional, Fagan, Madison M., additional, Scheulin, Kelly M., additional, Jeon, Julie H., additional, Shin, Soo K., additional, Kinder, Holly A., additional, Kumar, Anil, additional, Platt, Simon R., additional, Duberstein, Kylee J., additional, Park, Hea Jin, additional, Xie, Jin, additional, and West, Franklin D., additional

Published
2021
Full Text
View/download PDF

7. Characterization of tissue and functional deficits in a clinically translational pig model of acute ischemic stroke

Author

Kaiser, Erin E., primary, Waters, Elizabeth S., additional, Fagan, Madison M., additional, Scheulin, Kelly M., additional, Platt, Simon R., additional, Jeon, Julie H., additional, Fang, Xi, additional, Kinder, Holly A., additional, Shin, Soo K., additional, Duberstein, Kylee J., additional, Park, Hea J., additional, and West, Franklin D., additional

Published
2020
Full Text
View/download PDF

8. Acute characterization of tissue and functional deficits in a clinically translatable pig model of ischemic stroke

Author

Kaiser, Erin E., primary, Waters, Elizabeth S., additional, Fagan, Madison M., additional, Scheulin, Kelly M., additional, Platt, Simon R., additional, Jeon, Julie H., additional, Fang, Xi, additional, Kinder, Holly A., additional, Shin, Soo K., additional, Duberstein, Kylee J., additional, Park, Hea J., additional, and West, Franklin D., additional

Published
2019
Full Text
View/download PDF

9. An Adolescent Porcine Model of Voluntary Alcohol Consumption Exhibits Binge Drinking and Motor Deficits in a Two Bottle Choice Test.

Author

Shin, Soo K, Sneed, Sydney E, Nennig, Sadie E, Cheek, Savannah R, Kinder, Holly A, Solomon, Matthew G, Schank, Jesse R, and West, Franklin D

Subjects
*BIOLOGICAL models, *GAIT in humans, *ANIMAL experimentation, *BINGE drinking, *MOVEMENT disorders, *ALCOHOLIC intoxication, *SWINE, *SACCHARIN, *WATER, *DRUG use testing, *DIAGNOSIS, *DESCRIPTIVE statistics, *ALCOHOL drinking, *ETHANOL
Abstract

Aims Alcohol is the most commonly abused substance leading to significant economic and medical burdens. Pigs are an attractive model for studying alcohol abuse disorder due to the comparable alcohol metabolism and consumption behavior, which are in stark contrast to rodent models. This study investigates the usage of a porcine model for voluntary binge drinking (BD) and a detailed analysis of gait changes due to motor function deficits during alcohol intoxication. Methods Adolescent pigs were trained to drink increasing concentration (0–8%) of alcohol mixed in a 0.2% saccharin solution for 1 h in a two bottle choice test for 2 weeks. The training period was followed by a 3-week alcohol testing period, where animals were given free access to 8% alcohol in 0.2% saccharin solution and 0.2% saccharin water solution. Blood alcohol levels were tested and gait analysis was performed pre-alcohol consumption, last day of training, and Day 5 of each testing period. Results Pigs voluntarily consumed alcohol to intoxication at all timepoints with blood alcohol concentration (BAL) ≥80 mg/dl. Spatiotemporal gait parameters including velocity, cadence, cycle time, swing time, stance time, step time, and stride length were perturbed as a result of intoxication. The stratification of the gait data based on BAL revealed that the gait parameters were affected in a dose-dependent manner. Conclusion This novel adolescent BD porcine model with inherent anatomical and physiological similarities to humans display similar consumption and intoxication behavior that is likely to yield results that are translatable to human patients. [ABSTRACT FROM AUTHOR]

Published
2021
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results