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An analysis of fiber mechanics during cutting is conducted using a rotating cutting set up. It was found that high cutting speeds, low cutting angles, and high cutting normal forces lead to low values of cutting force. In this study, a set of high performance organic and inorganic fiber types are tested throughout different conditions of cut testing. Inorganic fibers gave the lowest specific cutting force. Values of cutting stresses on the edge of the blade were proved to be a function of fibers’ Young’s moduli. Higher Young’s moduli give lower cutting stresses on the blade edge while cutting fibers. Organic fibers were found to have a higher cutting resistance than carbon and glass fibers. A significant indirect correlation was found between the shear stress of the fibers and the fiber Young’s modulus. The value of the cutting force is significantly affected by both normal force and cutting velocity. The analysis of fiber mechanics during cutting is conducted using a rotating cutting set-up. It was found that high cutting speeds, low cutting angles, and high cutting normal forces lead to low values of cutting force. In this study, a set of high performance organic and inorganic fiber types are tested throughout different conditions of cut testing. Inorganic fibers gave the lowest specific cutting force. Values of cutting stresses on the edge of the blade were proved to be a function of fibers Young’s modulus. Higher Young’s modulus gives lower cutting stresses on the blade edge while cutting fibers. Organic fibers were found to have a higher cutting resistance than carbon and glass fibers. A significant indirect correlation was found between the shear stress of the fibers and the fibers Young’s modulus. The value of the cutting force is significantly affected by the normal force, cutting angle, and cutting velocity.

Introduction: Mesostyle is a needle free mesotheraputic device that is able to insert analytical pure active substance to the deep layers of skin within cell levels using the most modern electroporation procedure. Objectives: this study aimed to assess electroporation "as a method of transdermal administration of medications" in treatment of corticosteroid induced striae in systemic lupus erythematosus patients. Methods: Twenty female Systemic lupus erythematous (SLE) patients suffering from corticosteroid induced striae in different body parts, were included in this study. Patients were subjected to full history taking, complete clinical examination, and assessment of disease activity using systemic lupus erythematosus disease activity index (SLEDAI) score. Each patient received treatment in the form of six weekly successive cessions using electroporation device "Mesostyle" and photos were obtained after each cession. Results: We found marked improvement of striae appearance with noticeable patients’ satisfaction without any adverse effects. Conclusion: This study supports the role of electroporation which is safe, tolerable, non-invasive, and effective method for transdermal administration of medications.