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Atmospheric concentrations of PM2.5 and PM10 were measured in Beirut, Lebanon, for a period of 12 months. The daily average concentrations of PM10 and PM2.5 were found to be 51.3 ± 33.1 and 30.3 ± 9.4 µg.m-3, respectively, with corresponding maximum values of 359.7 and 208.6 µg.m-3. The annual average concentrations of PM10 and PM2.5 exceeded the World Health Organization's standards by 150% and 200%, respectively. The mean concentration of coarse particles (PM10-2.5) was found to be 41% of the average PM10, suggesting that the site was also influenced by re-suspended surface dust and soil. The mean PM2.5/PM10 ratio for the entire study period was 0.61 ± 0.12. This indicates that in Beirut, PM2.5 accounts for about 61% of PM10. Such a large fraction of fine particles could have considerable effect on health; thus, it is necessary to quantify its impact. Daily concentrations of PM10 and PM2.5 exceeded the upper threshold limit on 133 and 129 days, respectively, representing 39% and 38% of the entire sample, respectively. These findings indicate the important role dust events play within this area. Concentrations of PM2.5 were highly correlated with NO2, whereas concentrations of PM10 and PM10-2.5 were not associated with any gaseous pollutant. Regression analysis showed that 93% of PM2.5 and 43% of PM10 particle mass concentrations were derived from road traffic exhaust in Beirut. [ABSTRACT FROM AUTHOR]

Background In the past decade, waterpipe smoking— also known as hookah, shisha, narghileh—has increased among youth. The scarcity of rigorous studies linking waterpipe smoking to smoking-related diseases has hindered policy and regulatory efforts to confront the waterpipe epidemic. This study compares systemic carcinogen exposure between independent groups of exclusive waterpipe smokers, cigarette smokers and nonsmokers. Methods This study was conducted at the Syrian Center for Tobacco Studies (SCTS) in Aleppo, Syria, between 2010 and 2011. First morning urinary samples were collected from three groups of subjects; exclusive daily waterpipe smokers (n=24), exclusive daily cigarette smokers (n=23), and non-smokers (n=28). These samples were analysed for carcinogenic tobacco-specific nitrosamines 4-(methylnitrosamino)-1-(3-pyridyl)-1- butanol (NNAL) using liquid chromatography—tandem mass spectrometry (LC-MS/MS). Results Our results show that waterpipe smokers are exposed to about 5-10 times greater NNAL than nonsmokers. Mean (95% CI) free and total NNAL was 0.7 (0.3 to 1. 4) and 3.9 (1.6 to 9.5) pg/mL urine for nonsmokers, 8.4 (4.8 to 14.8) and 33.0 (21.6 to 50.6) pg/ mL urine for waterpipe smokers, and 10.7 (5.0 to 22.6) and 46.8 (27.6 to 79.3) pg/mL urine for cigarette smokers (p<0.001 for all comparisons). Daily waterpipe smokers were less exposed to NNAL than daily cigarette smokers, although the difference did not reach statistical significance for all measurements. Conclusions These results provide the clearest indication to date about systemic exposure to harmful carcinogens associated with long-term waterpipe smoking. Such evidence can support policy and regulatory efforts designed to confront the emerging global waterpipe epidemic, as well as drive interventions aimed at increasing the public awareness about the cancer risk associated with waterpipe smoking. [ABSTRACT FROM AUTHOR]