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Shuai Zhou, Chao Zhu, Shi Lei Chen, Jin Ang Li, Kang Lin Qu, Hao Jing, Yong Wang, Qing Pang, Hui Chun Liu Department of Hepatobiliary Pancreatic Surgery, Hepatobiliary Pancreatic Surgery, The First Affiliated Hospital of Bengbu Medical College, Anhui, 233000, People’s Republic of ChinaCorrespondence: Hui Chun Liu; Qing PangDepartment of Hepatobiliary Pancreatic Surgery, Hepatobiliary Pancreatic Surgery, The First Affiliated Hospital of Bengbu Medical College, Anhui, 233000, People’s Republic of ChinaEmail liuhcdoctor@126.com; portxiu2@126.comBackground: Pancreatic cancer is an aggressive malignant tumor of the digestive system and the fourth leading cause of tumor-related death. Intracavitary 125I seed irradiation has been recently developed as a therapy for locally advanced pancreatic head carcinoma. However, there are still many limitations, and more investigations are needed in order to optimize this new treatment method.Methods: Sixty-seven patients were included in our study; 41 cases treated by SEMS-CL-125I intracavular irradiation (SEMS-CL-125I group) and 26 cases treated by SEMS-CL-125I intracavular irradiation combined with 125I particle implantation in the tumor body (the combined group). Among the 67 patients, 43 were males and 24 were females, with an average age of 69.64± 8.84 years. Tumor site size was determined based on the MRI or CT imaging scans, and the number and radius of 125I particle placement were calculated according to a specific formula. 125I particles were inserted into the tumor with a radius of 1.5 cm and a row spacing of 1 cm. The main postoperative biochemical indexes, imaging analysis, postoperative analgesia degree, median survival time and rate of complications were compared between the two groups.Results: Jaundice and liver function improved in both groups after treatment for 6 months. The combined group did better. Kaplan–Meier analysis showed that patients in the combined group had a significantly better overall survival than those in the SEMS-CL-125I group. Patients in the combined group had less complications than those in the SEMS-CL-125I group (23.1% vs 34.1%), and the postoperative pain status of the combined group was improved (26.8% vs 53.8%).Conclusion: Compared with the SEMS-CL-125I intracavular irradiation alone, the combination of 125I seed implantation with solid tumor 125I seed implantation had a better therapeutic effect in LAPHC patients, with improved biochemical indicators, survival prognosis, pain relief, and fewer complications.Keywords: locally advanced pancreatic cancer, 125I, metal biliary stent

Because of the complex geologic space body and the underground seepage conditions, it is difficult to predict groundwater water inflow in prevention and treatment control work of coal mine. To predict the groundwater flow of the coal seam under the roof sandstone aquifer in Nanshan coal, the big water well method and three-dimensional numerical model were used at the same time. The quantity of predicted normal water inflow was 553.5 m3/h by using numerical model and the big-well method is about 591.6 m3/h. The result of big-well methods was relatively close to the result of numerical simulation method, which proved the rationality of the two methods in parameters selection and model building, and greatly improved the reliability and accuracy of prediction results. Compared with large-well method, by establishing the complex 3D geological structure of underground water and fitting the parameters based on the actual data of hydrology, numerical method could simulate the process of groundwater seepage and dewatering engineering, overcome the parameter uncertainty of large-well method, improve the predictive accuracy of the mine water inflow, and has important application value.

According to the low accuracy of velocity filed in current software, we develop a new system to analyze and visualize the 3D groundwater flow field. We employ the most advanced algorithm to deal with the data form groundwater simulation. The system could compute the flux across arbitrary face and the velocity of arbitrary point in the research domain. The system is debugged in Microsoft Visual Studio. The interactive interface is developed in .Net and the visualization tool is OpenGL. The application shows that the system is robust.

In order to figure out seepage field in aquifer under the coal seam, the geology and hydrogeology conditions systematically of study area were analyzed, hydrogeological conceptual model was generalized, mathematical model was built, seepage field of the Taiyuan limestone aquifer was simulated with software Feflow. Simulation results show that hydrogeological parameters of Taiyuan limestone aquifer change greatly in different partitions. The model also indicates the heterogeneity of karst fissure of Taiyuan limestone aquifer. The drainage quantity is from the Ordovician limestone aquifer besides supplying from runoff of upstream and capture excretion of downstream. The research is an attempt to simulate the seepage field in aquifer under coal seam, to some extent, it also provides a technical basis for safe coal mining and as a reference for simulation constructions of three-dimensional groundwater flow models in similar coal mines.

The development of mineral resources is accompanied by serious threats to the geological environment in China. In order to balance mining order, mine environmental protection and ecological restoration, this article examines a case study of Ningwu mining area and proposes an accurate method for mine dynamic monitoring in mining area based on remote sensing (RS), which is a series of technical processes with RS images selection, mine development situation and dynamic monitoring which includes areas change and types transfer. Findings indicate that the area of bauxite pit, bauxite and coal dump increased, the area of coal industrial square decreased, coal dump and industrial square mainly transferred into bauxite pit. The organization and storage model were discussed for results integrated management by spatial database engine (ArcSDE).The application of results retrieval was developed by GIS components. This method can be considered as an effective approach for a wide range of mine development monitoring in mining areas in China.

On the basis of the geology and hydrogeology, a three-dimensional numerical groundwater model in the study area was developed to evaluate the deep groundwater resources and avoid the groundwater level declining. According to the long-term water supply plan, water resources characteristics and exploitation status quo of Huantai county, three kinds of groundwater utilization scheme had been designed. The best sustainable groundwater exploitation scheme is determined by using the numerical model to simulate three kinds of mining schemes and analyze the corresponding groundwater flow field. The result shows that maintaining the status quo mining conditions will make the groundwater level decline further. Only reducing industrial exploitation and keeping domestic water mining can improve the conditions, but still difficult to solve the problem. The aim of utilization of deep groundwater can achieve only by reducing disordered water exploitation for production and living.

In order to improve the visible light response in titania photocatalysts, CuO/TiO2heterojunction nanostructures (CuO-TNT) were proposed and fabricated via the electrochemical process. TiO2nanotubes array (TNT) was first fabricated by secondary anodization, after that the CuO was doped by the electrodeposition. The thin film was characterized by X-ray diffraction (XRD), diffuse reflection spectra (DRS) and field emission scanning electron microscopy (FESEM). Besides, its photoelectrochemical properties were measured in 0.1 M Na2SO3solution. By comparing the results under different conditions of deposition, it was found that the deposition current density was a crucial parameter for controlling the morphology and the photoelectrochemical properties of the samples.