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Additional file 1: Supplemental Table 1. Basic characteristics of 39,353 patients with thyroid function. Supplemental Table 2. Age-standardized detection rates of TNs in Hunan Province from 2010 to 2019, stratified by tumor size, all age, both sexes. Supplemental Table 3. Age-standardized detection rates of TNs in Hunan Province from 2010 to 2019, stratified by age, all tumor sizes, both sexes. Supplemental Table 4. Age-standardized detection rates of TNs in Hunan Province from 2010 to 2019, stratified by sex, all tumor sizes, all ages. Supplemental Figure 1. Trends in TNs Detection Rates, Stratified by Sex, all ages, 2010–2019. Supplemental Figure 2. Trends in TNs Detection Rates, Stratified by age, all tumor sizes, 2010–2019. Supplemental Figure 3. Trends in Detection Rates of TNs with the maximum diameter > 1 cm, Stratified by age, 2010–2019. Supplemental Figure 4. Trends in Detection Rates of TNs with the maximum diameter ≤ 1 cm, Stratified by age, 2010–2019. Supplemental Figure 5. Multivariable Regression Models for TSH Level with Restricted Cubic Splines.

Additional file 13. Materials and methods.