Search

Background/purpose: Many studies have confirmed that periodontal disease interacts with diabetes. The aim of this study was to examine whether the advanced glycosylated end products (AGEs), which are generated by diabetics, have important effects on the osteogenic differentiation of periodontal ligament stem cells (PDLSCs). Materials and methods: In this study PDLSCs were isolated from the periodontal ligaments of extracted third molar teeth. The subjects were divided into two groups, which included the normal control group (N-PDLSCs) and the AGEs-stimulating group (A-PDLSCs). Changes of receptor of AGEs (RAGE) and cumulative ROS in PDLSCs were monitored by western blot and flow cytometry, respectively. Results: In the study AGEs noticeably inhibited the osteogenic differentiation of PDLSCs, with significant lower calcification nodules detected in A-PDLSCs (P

Nowadays, the qualification examination of practicing doctors has been one of the important criteria for the selection of health talents in China, while teaching reform has always been the priority in the teaching work of colleges and universities. This paper discusses the significant measures of teaching reform in colleges and universities through its examination results. To explore the test strategies for both Chinese and oversea students from Hainan Medical University based on the status of the qualification examination of practicing doctors in The School of Dentistry. Through the National Medical Examination Center, we collected basic information, average scores and the success rates in various medical sections and different subjects tested in the qualification examinations for dental practitioners who graduated from Hainan Medical University in 2011-2016, which were compared with the national corresponding parts. From 2011 to 2016, the number of practicing doctors taking the dental exam nationwide increased, and accounted for 1.2% of the number of candidates nationally. In 2016, the comprehensive written test and total success rates of candidates at Hainan Medical University decreased by nearly 9% compared with the national average, with a statistically significant difference in the written test results (P

Children's oral health is the foundation of a healthy life. Dental caries is a common disease among children, which not only affects children's physical and mental health, but also has a negative impact on their families and the surrounding social environment. The world health organization (WHO) and the international dental union (FDI) have established a 2020 global goal for oral health. At present, the prevalence of dental caries among children in China is high, the awareness rate of oral health knowledge and behavioral development is low, the ability of oral health services at the grassroots level is weak, and the oral health work of children needs to be strengthened. This paper is a review paper and examines the basis of the disease and the recent studies carried out in various parts of The Peoples Republic of China, including the Hong Kong Special Administrative area. It recommended that oral hygiene be included in school curricula as part of children's general education, and called on Chinese teachers and parents to participate. At the same time, it is suggested that oral health care programmes be incorporated into general health education programmes and that children with dental caries be encouraged to take further active treatment in time.