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144 results on '"Shen, Xubo"'

9. Risk assessment and environmental determinants of urinary phthalate metabolites in pregnant women in Southwest China

Author

Wu, Nian, Tao, Lin, Tian, Kunming, Wang, Xia, He, Caidie, An, Songlin, Tian, Yingkuan, Liu, Xiang, Chen, Wei, Zhang, Haonan, Xu, Pei, Liao, Dengqing, Liao, Juan, Wang, Linglu, Fang, Derong, Hu, Zhongmei, Yuan, Hongyu, Huang, Jingyi, Chen, Xiaoshan, Zhang, Li, Hou, Xiaohui, Zeng, Rong, Liu, Xingyan, Xiong, Shimin, Xie, Yan, Liu, Yijun, Li, Quan, Shen, Xubo, Zhou, Yuanzhong, and Shang, Xuejun

Published
2023
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10. Effects of exposure to phthalate during early pregnancy on gestational diabetes mellitus: a nested case–control study with propensity score matching

Author

Chen, Wei, He, Caidie, Liu, Xiang, An, Songlin, Wang, Xia, Tao, Lin, Zhang, Haonan, Tian, Yingkuan, Wu, Nian, Xu, Pei, Liao, Dengqing, Liao, Juan, Wang, Linglu, Fang, Derong, Xiong, Shimin, Liu, Yijun, Tian, Kunming, Li, Quan, Huang, Jingyi, Yuan, Hongyu, Chen, Xiaoshan, Zhang, Li, Shen, Xubo, and Zhou, Yuanzhong

Published
2023
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17. Research Progress on Animal Model for Cancer-related Fatigue

Author

JIN Ming, XIE Lulu, MAO Ni, SHEN Xubo, WEI Jianzi, SHEN Xueyong, and MAO Huijuan

Subjects
cancer, cancer-related fatigue, animal models, modeling method, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Cancer-related fatigue (CRF) is a common symptom which associated with cancer itself or cancer treatments. CRF will not only interrupt the patient's treatment, but also affect the patient's quality of life seriously. To date, the pathogenesis of CRF is still unclear, and recognized effective treatment is lacking. It is the precondition of establishing standardized animal models for CRF to find effective treatments. This paper summarizes the animal model of CRF in order to find suitable methods, and distinguish the effects of different interventions.

Published
2021
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19. Exposure levels and determinants of placental polybrominated diphenyl ethers in Chinese pregnant women

Author

Liu, Yijun, primary, Xie, Yan, additional, Tian, Yingkuan, additional, Liao, Juan, additional, Fang, Derong, additional, Wang, Linglu, additional, Zeng, Rong, additional, Xiong, Shimin, additional, Liu, Xingyan, additional, Chen, Qing, additional, Zhang, Ya, additional, Yuan, Hongyu, additional, Li, Quan, additional, Shen, XuBo, additional, and Zhou, Yuanzhong, additional

Published
2023
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21. Co-Exposure of Polycyclic Aromatic Hydrocarbons and Phthalates with Blood Cell-Based Inflammation in Early Pregnant Women

Author

Yang, Yunxiao, primary, Wang, Ting, additional, Luo, Lei, additional, He, Qian, additional, Guo, Fangfei, additional, Chen, Zhongbao, additional, Liu, Yijun, additional, Liu, Xingyan, additional, Xie, Yan, additional, Shang, Xuejun, additional, Shen, Xubo, additional, Zhou, Yuanzhong, additional, and Tian, Kunming, additional

Published
2023
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22. Association of central obesity with sex hormonebinding globulin: a cross-sectional study of 1166 Chinese men

Author

Liu Fangwei, Shen Xubo, Wang Ruifeng, Yu Na, Shi Yongjun, Xiong Shimin, Xiong Chengliang, and Zhou Yuanzhong

Subjects
cardiovascular risk, metabolism, cross-sectional study, Medicine
Abstract

Background Both sex hormone-binding globulin and central obesity have been found to be associated with metabolic and cardiovascular diseases. However, the direct relation between sex hormone-binding globulin and central obesity has not been demonstrated.

Published
2018
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24. Establishment and validation of a prediction model for gestational diabetes.

Author

Wang, Xia, He, Caidie, Wu, Nian, Tian, Yingkuan, An, Songlin, Chen, Wei, Liu, Xiang, Zhang, Haonan, Xiong, Shimin, Liu, Yijun, Li, Quan, Zhou, Yuanzhong, and Shen, Xubo

Subjects
PREDICTION models, GESTATIONAL diabetes, POLLUTANTS, PREGNANT women, MODEL validation, REGRESSION analysis
Abstract

Aim: To develop a visual prediction model for gestational diabetes (GD) in pregnant women and to establish an effective and practical tool for clinical application. Methods: To establish a prediction model, the modelling set included 1756 women enrolled in the Zunyi birth cohort, the internal validation set included 1234 enrolled women, and pregnant women in the Wuhan cohort were included in the external validation set. We established a demographic–lifestyle factor model (DLFM) and a demographic–lifestyle–environmental pollution factor model (DLEFM) based on whether the women were exposed to environmental pollutants. The least absolute shrinkage and selection lasso–logistic regression analyses were used to identify the independent predictors of GD and construct a nomogram for predicting its occurrence. Results: The DLEFM regression analysis showed that a family history of diabetes (odd ratio [OR] 2.28; 95% confidence interval [CI] 1.05‐4.71), a history of GD in pregnant women (OR 4.22; 95% CI 1.89‐9.41), being overweight or obese before pregnancy (OR 1.71; 95% CI 1.27‐2.29), a history of hypertension (OR 2.61; 95% CI 1.41‐4.72), sedentary time (h/day) (OR 1.16; 95% CI 1.08‐1.24), monobenzyl phthalate (OR 1.95; 95% CI 1.45‐2.67) and Q4 mono‐ethyl phthalate concentration (OR 1.85; 95% CI 1.26‐2.73) were independent predictors. The area under the receiver operating curves for the internal validation of the DLEFM and the DLFM constructed using these seven factors was 0.827 and 0.783, respectively. The calibration curve of the DLEFM was close to the diagonal line. The DLEFM was thus the more optimal model, and the one which we chose. Conclusions: A nomogram based on preconception factors was constructed to predict the occurrence of GD in the second and third trimesters. It provided an effective tool for the early prediction and timely management of GD. [ABSTRACT FROM AUTHOR]

Published
2024
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28. Effects of exposure to phthalate during early pregnancy on gestational diabetes mellitus: a nested case–control study with propensity score matching

Author

Chen, Wei, primary, He, Caidie, additional, Liu, Xiang, additional, An, Songlin, additional, Wang, Xia, additional, Tao, Lin, additional, Zhang, Haonan, additional, Tian, Yingkuan, additional, Wu, Nian, additional, Xu, Pei, additional, Liao, Dengqing, additional, Liao, Juan, additional, Wang, Linglu, additional, Fang, Derong, additional, Xiong, Shimin, additional, Liu, Yijun, additional, Tian, Kunming, additional, Li, Quan, additional, Huang, Jingyi, additional, Yuan, Hongyu, additional, Chen, Xiaoshan, additional, Zhang, Li, additional, Shen, Xubo, additional, and Zhou, Yuanzhong, additional

Published
2022
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29. Characteristics of exposure to 10 polycyclic aromatic hydrocarbon metabolites among pregnant women: cohort of pregnant women in Zunyi, southwest China

Author

Tian, Yingkuan, primary, Zhang, Renjuan, additional, Liu, Xiang, additional, Liu, Yijun, additional, Xiong, Shimin, additional, Wang, Xia, additional, Zhang, Haonan, additional, Li, Quan, additional, Liao, Juan, additional, Fang, Derong, additional, Wang, Linglu, additional, Zhang, Ya, additional, Yuan, Hongyu, additional, Zhang, Li, additional, He, Caidie, additional, An, Songlin, additional, Chen, Wei, additional, Zhou, Yuanzhong, additional, and Shen, Xubo, additional

Published
2022
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30. Maternal urine phthalate metabolite exposure and miscarriage risk: a nested case–control study of the Zunyi Birth Cohort

Author

Wang, Xia, primary, He, Caidie, additional, Wu, Nian, additional, Tian, Yingkuan, additional, Wang, Linglu, additional, Liao, Juan, additional, Fang, Derong, additional, Liu, Xiang, additional, An, Songlin, additional, Chen, Wei, additional, Xiong, Shimin, additional, Liu, Yijun, additional, Xie, Yan, additional, Tian, Kunming, additional, Huang, Jingyi, additional, Yuan, Hongyu, additional, Chen, Xiaoshan, additional, Zhang, Li, additional, Li, Quan, additional, Shen, Xubo, additional, and Zhou, Yuanzhong, additional

Published
2022
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31. Is greener better? Associations between greenness and birth outcomes in both urban and non-urban settings

Author

Xiao, Xiang, Gao, Meng, Zhou, Yang, Xu, Shu-li, Knibbs, Luke D., Heinrich, Joachim, Dharmage, Shyamali C, Morawska, Lidia, Lin, Shao, Jalaludin, Bin, Shen, Xubo, Zhou, Yuanzhong, Dong, Guang-Hui, Xiao, Xiang, Gao, Meng, Zhou, Yang, Xu, Shu-li, Knibbs, Luke D., Heinrich, Joachim, Dharmage, Shyamali C, Morawska, Lidia, Lin, Shao, Jalaludin, Bin, Shen, Xubo, Zhou, Yuanzhong, and Dong, Guang-Hui

Abstract

Background: Beneficial effects of greenness on birth outcomes have been reported, but few studies have investigated the associations in both urban and non-urban settings. We aimed to evaluate and compare linear and nonlinear associations between greenness and birth outcomes in urban and non-urban settings. Methods: From October 2015 to December 2018, participants were recruited into the Maoming Birth Cohort Study. A total of 11 258 live birth records were obtained. Greenness exposure was assessed using the normalized difference vegetation index (NDVI) and enhanced vegetation index (EVI). Linear regression and nonlinear restricted cubic spline models were implemented to investigate the associations between greenness and birthweight, birth length, gestational age, preterm birth, low birthweight, small for gestational age and the potential for effect variation under urban or non-urban settings, after adjusting for covariates. Results: A 0.1-unit increase in NDVI-500m was significantly associated with an increase of 35.4 g in birthweight [95% confidence interval (CI): 13.2, 57.7], 0.15 cm in birth length (95% CI: 0.03, 0.26), 0.88 days in gestational age (95% CI: 0.05, 1.71) and lower odds of low birthweight [odds ratio (OR) = 0.69, 95% CI: 0.56, 0.85] and preterm birth (OR = 0.70, 95% CI: 0.58, 0.85). No association with head circumference was observed. For all outcomes, no significant linear associations were observed among non-urban dwellers. Inversed 'U-shaped' associations between greenness exposure and birth outcomes were observed in the total study population. Conclusions: Greenness exposure was associated with increased gestational age, birthweight and birth length in urban dwellers. Nonlinear associations assessed by restricted cubic splines suggested that health benefits could be larger when increasing greenness levels from low to medium compared with increasing greenness from medium to high levels. Further studies adopting nonlinear methods are warranted t

Published
2022

32. Chlorinated Polyfluorinated Ether Sulfonates and Thyroid Hormone Levels in Adults: Isomers of C8 Health Project in China

Author

Li, Qing-Qing, primary, Liu, Jiao-Jiao, additional, Su, Fan, additional, Zhang, Yun-Ting, additional, Wu, Lu-Yin, additional, Chu, Chu, additional, Zhou, Yuanzhong, additional, Shen, Xubo, additional, Xiong, Shimin, additional, Geiger, Sarah Dee, additional, Qian, Zhengmin Min, additional, McMillin, Stephen Edward, additional, Dong, Guang-Hui, additional, and Zeng, Xiao-Wen, additional

Published
2022
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34. Exposure Characteristics of Phthalate Metabolites Among The Zunyi Cohort of Pregnant Women in Southwest China

Author

Liao, Juan, primary, Fang, Derong, additional, Liu, Yijun, additional, Xiong, Shimin, additional, Wang, Xia, additional, Tian, Yingkuan, additional, Zhang, Haonan, additional, An, Songlin, additional, He, Caidie, additional, Chen, Wei, additional, Liu, Xiang, additional, Wu, Nian, additional, Tian, Kunming, additional, Wang, Linglu, additional, Zhang, Ya, additional, Yuan, Hongyu, additional, Zhang, Li, additional, Li, Quan, additional, Shen, Xubo, additional, and Zhou, Yuanzhong, additional

Published
2022
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35. The effects of Cl-PFESAs exposure on blood lipids – A community-based large population study in Guangzhou

Author

Mi, Xin, primary, Wu, Lu-Yin, additional, Liu, Jiao-Jiao, additional, Fang, Qiu-Ling, additional, Qian, Zhengmin (Min), additional, Chu, Chu, additional, Li, Qing-Qing, additional, Su, Fan, additional, Zhang, Yun-Ting, additional, Zhou, Peien, additional, Zeng, Xiao-Wen, additional, Yu, Hong-Yao, additional, Dong, Pengxin, additional, Zhou, Yang, additional, Ou, Yanqiu, additional, Xiong, Shimin, additional, Shen, Xubo, additional, Feng, Wenru, additional, Zhou, Yuanzhong, additional, and Dong, Guang-Hui, additional

Published
2022
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36. Association between eye-level greenness and lung function in urban Chinese children

Author

Yu, Hongyao, primary, Hu, Li-Wen, additional, Zhou, Yang, additional, Qian, Zhengmin, additional, Schootman, Mario, additional, LeBaige, Morgan H., additional, Zhou, Yuanzhong, additional, Xiong, Shimin, additional, Shen, Xubo, additional, Lin, Li-Zi, additional, Zhou, Peien, additional, Liu, Ru-Qing, additional, Yang, Bo-Yi, additional, Chen, Gongbo, additional, Zeng, Xiao-Wen, additional, Yu, Yunjiang, additional, and Dong, Guang-Hui, additional

Published
2021
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37. The Asthma Family Tree: Evaluating Associations Between Childhood, Parental, and Grandparental Asthma in Seven Chinese Cities

Author

Yu, Hongyao, primary, Su, Fan, additional, Wang, Le-Bing, additional, Hemminki, Kari, additional, Dharmage, Shyamali C., additional, Bowatte, Gayan, additional, Bui, Dinh, additional, Qian, Zhengmin, additional, Vaughn, Michael G., additional, Aaron, Hannah E., additional, Xiong, Shimin, additional, Shen, Xubo, additional, Zhou, Yuanzhong, additional, Zhou, Peien, additional, Zeng, Xiao-Wen, additional, Chen, Gongbo, additional, Yang, Bo-Yi, additional, Hu, Li-Wen, additional, and Dong, Guang-Hui, additional

Published
2021
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38. Exposure to isomers of per- and polyfluoroalkyl substances increases the risk of diabetes and impairs glucose-homeostasis in Chinese adults: Isomers of C8 health project

Author

Zeeshan, Mohammed, primary, Zhang, Yun-Ting, additional, Yu, Shu, additional, Huang, Wen-Zhong, additional, Zhou, Yang, additional, Vinothkumar, Rajamanickam, additional, Chu, Chu, additional, Li, Qing-Qing, additional, Wu, Qi-Zhen, additional, Ye, Wan-Lin, additional, Zhou, Peien, additional, Dong, Pengxin, additional, Zeng, Xiao-Wen, additional, Hu, Li-Wen, additional, Yang, Bo-Yi, additional, Shen, Xubo, additional, Zhou, Yuanzhong, additional, and Dong, Guang-Hui, additional

Published
2021
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39. Is greener better? Associations between greenness and birth outcomes in both urban and non-urban settings

Author

Xiao, Xiang, primary, Gao, Meng, additional, Zhou, Yang, additional, Xu, Shu-Li, additional, Knibbs, Luke D, additional, Heinrich, Joachim, additional, Dharmage, Shyamali C, additional, Morawska, Lidia, additional, Lin, Shao, additional, Jalaludin, Bin, additional, Shen, Xubo, additional, Zhou, Yuanzhong, additional, and Dong, Guang-Hui, additional

Published
2021
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40. Maternal exposure to ambient air pollution and congenital heart defects in China

Author

Yang, Bo-Yi, primary, Qu, Yanji, additional, Guo, Yuming, additional, Markevych, Iana, additional, Heinrich, Joachim, additional, Bloom, Michael S., additional, Bai, Zhipeng, additional, Knibbs, Luke C., additional, Li, Shanshan, additional, Chen, Gongbo, additional, Jalaludin, Bin, additional, Morawska, Lidia, additional, Gao, Meng, additional, Han, Bin, additional, Yu, Yunjiang, additional, Liu, Xiao-Xuan, additional, Ou, Yanqiu, additional, Mai, Jinzhuang, additional, Gao, Xiangmin, additional, Wu, Yong, additional, Nie, Zhiqiang, additional, Zeng, Xiao-Wen, additional, Hu, Li-Wen, additional, Shen, Xubo, additional, Zhou, Yuanzhong, additional, Lin, Shao, additional, Liu, Xiaoqing, additional, and Dong, Guang-Hui, additional

Published
2021
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41. Maternal exposure to ambient air pollution and congenital heart defects in China

Author

Yang, Bo-Yi, Qu, Yanji, Guo, Yuming, Markevych, Iana, Heinrich, Joachim, Bloom, Michael S., Bai, Zhipeng, Knibbs, Luke C., Li, Shanshan, Chen, Gongbo, Jalaludin, Bin, Morawska, Lidia, Gao, Meng, Han, Bin, Yu, Yunjiang, Liu, Xiao-xuan, Ou, Yanqiu, Mai, Jinzhuang, Gao, Xiangmin, Wu, Yong, Nie, Zhiqiang, Zeng, Xiao-Wen, Hu, Li-Wen, Shen, Xubo, Zhou, Yuanzhong, Lin, Shao, Liu, Xiaoqing, Dong, Guang-Hui, Yang, Bo-Yi, Qu, Yanji, Guo, Yuming, Markevych, Iana, Heinrich, Joachim, Bloom, Michael S., Bai, Zhipeng, Knibbs, Luke C., Li, Shanshan, Chen, Gongbo, Jalaludin, Bin, Morawska, Lidia, Gao, Meng, Han, Bin, Yu, Yunjiang, Liu, Xiao-xuan, Ou, Yanqiu, Mai, Jinzhuang, Gao, Xiangmin, Wu, Yong, Nie, Zhiqiang, Zeng, Xiao-Wen, Hu, Li-Wen, Shen, Xubo, Zhou, Yuanzhong, Lin, Shao, Liu, Xiaoqing, and Dong, Guang-Hui

Abstract

Background: Evidence of maternal exposure to ambient air pollution on congenital heart defects (CHD) has been mixed and are still relatively limited in developing countries. We aimed to investigate the association between maternal exposure to air pollution and CHD in China. Method: This longitudinal, population-based, case-control study consecutively recruited fetuses with CHD and healthy volunteers from 21 cities, Southern China, between January 2006 and December 2016. Residential address at delivery was linked to random forests models to estimate maternal exposure to particulate matter with an aerodynamic diameter of ≤1 µm (PM1), ≤2.5 µm, and ≤10 µm as well as nitrogen dioxides, in three trimesters. The CHD cases were evaluated by obstetrician, pediatrician, or cardiologist, and confirmed by cardia ultrasound. The CHD subtypes were coded using the International Classification Diseases. Adjusted logistic regression models were used to assess the associations between air pollutants and CHD and its subtypes. Results: A total of 7055 isolated CHD and 6423 controls were included in the current analysis. Maternal air pollution exposures were consistently higher among cases than those among controls. Logistic regression analyses showed that maternal exposure to all air pollutants during the first trimester was associated with an increased odds of CHD (e.g., an interquartile range [13.3 µg/m3] increase in PM1 was associated with 1.09-fold ([95% confidence interval, 1.01-1.18]) greater odds of CHD). No significant associations were observed for maternal air pollution exposures during the second trimester and the third trimester. The pattern of the associations between air pollutants and different CHD subtypes was mixed. Conclusions: Maternal exposure to greater levels of air pollutants during the pregnancy, especially the first trimester, is associated with higher odds of CHD in offspring. Further longitudinal well-designed studies are warranted to confirm our

Published
2021

42. Characteristics of exposure to 10 polycyclic aromatic hydrocarbon metabolites among pregnant women: cohort of pregnant women in Zunyi, southwest China

Author

Tian, Yingkuan, Zhang, Renjuan, Liu, Xiang, Liu, Yijun, Xiong, Shimin, Wang, Xia, Zhang, Haonan, Li, Quan, Liao, Juan, Fang, Derong, Wang, Linglu, Zhang, Ya, Yuan, Hongyu, Zhang, Li, He, Caidie, An, Songlin, Chen, Wei, Zhou, Yuanzhong, and Shen, Xubo

Abstract

ObjectiveOur aim was to elucidate the polycyclic aromatic hydrocarbon (PAH) metabolites exposure levels of pregnant women in the underdeveloped region of Zunyi, southwest China.MethodsSociodemographic information was collected via questionnaires, and urine samples were collected at the same time. A total of 3047 pregnant women participated in the study. Gas chromatography/mass spectrometry was used to detect the urine concentrations of 10 PAH metabolites. A generalised linear model (GLM) was used to identify predictive factors of PAH metabolites.ResultsAll PAH metabolites had a detection rate greater than 60% (67.21%–90.57%) except for 4-OH-PHE at 55.54%. The median concentrations were 0.02–0.11 µg/g Cre except for 1-OH-NAP, 2-OH-NAP, 2-OH-FLU and 9-OH-FLU (0.36–0.50 µg/g Cre). The cluster analysis identified the phenanthrene and fluorene metabolite clusters (containing no other metabolites), while naphthalene metabolites (1-OH-NAP, 2-OH-NAP) could not be clustered without other metabolites. GLM analysis identified that pregnant women with the following characteristics have high urinary concentration of PAH metabolites: overweight, in the last trimester of pregnancy, distance between their house and main traffic lines as <5 m, use fuel for cooking, passive smoking, renovated their residence for less than 3 years, middle family income and office workers.ConclusionThe results clarified pregnant women from the economically underdeveloped area could be the victims of PAHs. In addition, PAHs present a demographic and seasonal differential distribution, which will aid in the development of targeted interventions and reduce exposure to PAHs during pregnancy.

Published
2023
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44. Decreased testosterone secretion index and free testosterone level with multiple symptoms for late-onset hypogonadism identification: a nationwide multicenter study with 5980 aging males in China

Author

Li, Honggang, primary, Gu, Yiqun, additional, Shang, Xuejun, additional, Zhou, Yuanzhong, additional, Zhang, Huiping, additional, Zuo, Liandong, additional, Mei, Guangan, additional, Xia, Wei, additional, Guan, Huangtao, additional, Xiang, Wenpei, additional, Zhou, Shanjie, additional, Wan, Changchun, additional, Hao, Baojin, additional, Shen, Xubo, additional, Tang, Linguo, additional, Wu, Weixiong, additional, Qi, Ying, additional, Yu, Na, additional, Kong, Xiangbin, additional, Chen, Yaoping, additional, Yang, Yihong, additional, Qing, Xingrong, additional, and Xiong, Chengliang, additional

Published
2020
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48. Research progress on the relationship between sex hormone‐binding globulin and male reproductive system diseases.

Author

Wan, Qiyou, Xie, Yan, Zhou, Yuanzhong, and Shen, Xubo

Subjects
MALE reproductive organs, GLOBULINS, SEX hormones, GONADAL diseases, MALE infertility, ESTRADIOL, IMPOTENCE
Abstract

Sex hormone‐binding globulin, also known as testosterone–estradiol‐binding globulin, is a multifunctional protein synthesised by hepatocytes. Sex hormone‐binding globulin specifically binds and transports sex hormones to regulate plasma bioactive sex hormone levels and affects their bioavailability. As male sex hormone expression is dominated by testosterone, the binding of sex hormone‐binding globulin with testosterone leads to the reduction in bioavailable testosterone, which cannot fulfil its physiological roles, thereby resulting in male infertility, erectile and gonadal dysfunction, prostate cancer and other male reproductive system diseases. Sex hormone‐binding globulin may be involved in the pathogenesis of male reproductive system diseases, seriously affecting the quality of life of men. In this article, we review the association between sex hormone‐binding globulin and male reproductive system diseases. [ABSTRACT FROM AUTHOR]

Published
2021
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