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294 results on '"Shen, Shunli"'

1. Surgical treatment improves overall survival of hepatocellular carcinoma with extrahepatic metastases after conversion therapy: a multicenter retrospective study

Author

Zhang, Xiaoshi, Zhu, Xiaodong, Zhong, Jianhong, Zhao, Yang, Zhang, Xiaoyun, Zhang, Wenwen, Ye, Feng, Yang, Chaoxu, Xue, Jun, Xiong, Rui, Wang, Jiabei, Shen, Shunli, Pan, Yangxun, Li, Dongxiao, Song, Tianqiang, Bi, Xinyu, Sun, Huichuan, Xiang, Bangde, Gu, Shanzhi, Wen, Tianfu, Lu, Shichun, Chen, Yongjun, Yin, Tao, Liu, Lianxin, Kuang, Ming, Xu, Li, Li, Deyu, and Cai, Jianqiang

Published
2024
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5. FASN-mediated fatty acid biosynthesis remodels immune environment in Clonorchis sinensis infection-related intrahepatic cholangiocarcinoma

Author

Xu, Lixia, Zhang, Ying, Lin, Zhilong, Deng, Xinlang, Ren, Xiaoxue, Huang, Mingle, Li, Shangru, Zhou, Qianying, Fang, Fei, Yang, Qingxia, Zheng, Gaomin, Chen, Zebin, Wu, Zhongdao, Sun, Xi, Lin, Jie, Shen, Jingxian, Guo, Jianping, Li, Xiaoxing, Xue, Tianchen, Tan, Jing, Lin, Xiaoxuan, Tan, Li, Peng, Hong, Shen, Shunli, Peng, Sui, Li, Shaoqiang, Liang, Lijian, Cleary, James M., Lai, Jiaming, Xie, Yubin, and Kuang, Ming

Published
2024
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18. Predicting Pathological Response of Neoadjuvant Conversion Therapy for Hepatocellular Carcinoma Patients Using CT-Based Radiomics Model.

Author

Wen, Haoxiang, Liang, Ruiming, Liu, Xiaofei, Yu, Yang, Lin, Shuirong, Song, Zimin, Huang, Yihao, Yu, Xi, Chen, Shuling, Chen, Lili, Qian, Baifeng, Shen, Jingxian, Xiao, Han, and Shen, Shunli

Subjects
FEATURE extraction, NEOADJUVANT chemotherapy, RADIOMICS, PORTAL vein, HEPATOCELLULAR carcinoma
Abstract

Purpose: Predicting the pathological response after neoadjuvant conversion therapy for initially unresectable hepatocellular carcinoma (HCC) is essential for surgical decision-making and survival outcomes but remains a challenge. We aimed to develop a radiomics model to predict pathological responses. Methods: We included 203 patients with HCC who underwent hepatectomy after neoadjuvant conversion therapy between 2015 and 2023 and separated them into a training set (100 patients from Center A) and a validation set (103 patients from Center B). Pathological complete response (pCR)-related radiomic features were extracted from the largest tumor layer in the arterial and portal vein phases of the CT. A synthetic minority oversampling technique (SMOTE) was used to balance the minority groups in the training set. The SMOTE radiomics model was constructed using a logistic regression model in the SMOTE training set and its performance was verified in the validation set. Results: The AUC of the preoperative modified response evaluation criteria in solid tumors (mRECIST) assessment for pCR was 0.656 and 0.589 in the training and validation sets, respectively. The SMOTE radiomics model was established based on ten radiomic features and showed good pCR-predictive performance in the SMOTE training set (AUC, 0.889; accuracy, 87.7%) and the validation set (AUC: 0.843, accuracy: 86.4%). The RFS of the radiomics-predicted-pCR group was significantly better than that of the predicted-non-pCR group in the training cohort (P = 0.001, 2-year RFS: 69.5% and 30.1% respectively) and the validation cohort (P = 0.012, 2-year RFS: 65.9% and 38.0% respectively). Conclusion: The SMOTE radiomics model has great potential for predicting pathological response and evaluating RFS in patients with unresectable HCC after neoadjuvant conversion therapy. [ABSTRACT FROM AUTHOR]

Published
2024
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20. Toripalimab Plus Bevacizumab as First-line Treatment for Advanced Hepatocellular Carcinoma: A Prospective, Multicenter, Single-Arm, Phase II Trial

Author

Chen, Yajin, primary, Du, Cheng-You, additional, Shen, Shunli, additional, Zhang, Wu, additional, Shan, Yunfeng, additional, Lyu, Ang, additional, Wu, Jianhui, additional, Shang, Changzhen, additional, Luo, Xuan, additional, Wei, Jinxing, additional, Xiao, Heng, additional, Qiu, Jianguo, additional, Hua, Yunpeng, additional, Wang, Shutong, additional, Wang, Ting, additional, Dai, Shengjie, additional, Zhang, Shuhao, additional, Xie, Bingying, additional, Wu, Yinghao, additional, and Hao, Chunyi, additional

Published
2024
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21. Table S3 from Th17 Cells Secrete TWEAK to Trigger Epithelial–Mesenchymal Transition and Promote Colorectal Cancer Liver Metastasis

Author

Liu, Xin, primary, Wang, Xin, primary, Yang, Qingxia, primary, Luo, Li, primary, Liu, Ziqin, primary, Ren, Xiaoxue, primary, Lei, Kai, primary, Li, Shangru, primary, Xie, Zonglin, primary, Zheng, Gaomin, primary, Zhang, Yifan, primary, Hao, Yijie, primary, Zhou, Qianying, primary, Hou, Yingdong, primary, Fang, Fei, primary, Song, Wu, primary, Cui, Ji, primary, Ma, Jinping, primary, Xie, Wenxuan, primary, Shen, Shunli, primary, Tang, Ce, primary, Peng, Sui, primary, Yu, Jun, primary, Kuang, Ming, primary, Song, Xinming, primary, Wang, Fang, primary, and Xu, Lixia, primary

Published
2024
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22. Figure S9 from Th17 Cells Secrete TWEAK to Trigger Epithelial–Mesenchymal Transition and Promote Colorectal Cancer Liver Metastasis

Author

Liu, Xin, primary, Wang, Xin, primary, Yang, Qingxia, primary, Luo, Li, primary, Liu, Ziqin, primary, Ren, Xiaoxue, primary, Lei, Kai, primary, Li, Shangru, primary, Xie, Zonglin, primary, Zheng, Gaomin, primary, Zhang, Yifan, primary, Hao, Yijie, primary, Zhou, Qianying, primary, Hou, Yingdong, primary, Fang, Fei, primary, Song, Wu, primary, Cui, Ji, primary, Ma, Jinping, primary, Xie, Wenxuan, primary, Shen, Shunli, primary, Tang, Ce, primary, Peng, Sui, primary, Yu, Jun, primary, Kuang, Ming, primary, Song, Xinming, primary, Wang, Fang, primary, and Xu, Lixia, primary

Published
2024
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23. Data from Th17 Cells Secrete TWEAK to Trigger Epithelial–Mesenchymal Transition and Promote Colorectal Cancer Liver Metastasis

Author

Liu, Xin, primary, Wang, Xin, primary, Yang, Qingxia, primary, Luo, Li, primary, Liu, Ziqin, primary, Ren, Xiaoxue, primary, Lei, Kai, primary, Li, Shangru, primary, Xie, Zonglin, primary, Zheng, Gaomin, primary, Zhang, Yifan, primary, Hao, Yijie, primary, Zhou, Qianying, primary, Hou, Yingdong, primary, Fang, Fei, primary, Song, Wu, primary, Cui, Ji, primary, Ma, Jinping, primary, Xie, Wenxuan, primary, Shen, Shunli, primary, Tang, Ce, primary, Peng, Sui, primary, Yu, Jun, primary, Kuang, Ming, primary, Song, Xinming, primary, Wang, Fang, primary, and Xu, Lixia, primary

Published
2024
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24. Adjuvant Transarterial Chemoembolization With Sorafenib for Portal Vein Tumor Thrombus

Author

Peng, Zhenwei, primary, Fan, Wenzhe, additional, Liu, Zelong, additional, Xiao, Han, additional, Wu, Jian, additional, Tang, Rong, additional, Tu, Jianfei, additional, Qiao, Liangliang, additional, Huang, Fuxi, additional, Xie, Wenxuan, additional, Zhuang, Wenquan, additional, Guo, Wenbo, additional, Li, Shaoqiang, additional, Hua, Yunpeng, additional, Shen, Shunli, additional, He, Qiang, additional, Li, Dongming, additional, Li, Jiaping, additional, and Kuang, Ming, additional

Published
2024
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26. The long-term efficacy of imatinib with hepatic resection or other local treatment for gastrointestinal stromal tumours liver metastases：a retrospective cohort study

Author

Wen, Haoxiang, primary, Huang, Yihao, additional, Huang, Shaoqing, additional, Xiao, Han, additional, Xie, Wenxuan, additional, Zhou, Qian, additional, Tan, Li, additional, Ding, Yuqi, additional, Liu, Xiaofei, additional, Yu, Yang, additional, Song, Zimin, additional, Shen, Shunli, additional, Chen, Zebin, additional, and Zhang, Xinhua, additional

Published
2024
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28. Personalized drug screening in patient-derived organoids of biliary tract cancer and its clinical application

Author

Ren, Xiaoxue, primary, Huang, Mingle, additional, Weng, Weixiang, additional, Xie, Yubin, additional, Wu, Yifan, additional, Zhu, Shenghua, additional, Zhang, Ying, additional, Li, Dongming, additional, Lai, Jiaming, additional, Shen, Shunli, additional, Lin, Jie, additional, Kuang, Ming, additional, Li, Xiaoxing, additional, Yu, Jun, additional, and Xu, Lixia, additional

Published
2023
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30. Hypoxia-driven tumor stromal remodeling and immunosuppressive microenvironment in scirrhous hepatocellular carcinoma

Author

Chen, Shuling, primary, Liao, Changyi, additional, Hu, Huanjing, additional, Liao, Junbin, additional, Chen, Zebin, additional, Li, Shuang, additional, Zeng, Xuezhen, additional, Peng, Bo, additional, Shen, Shunli, additional, Li, Dongming, additional, Li, Shaoqiang, additional, Lai, Jiaming, additional, Peng, Sui, additional, Xie, Yubin, additional, and Kuang, Ming, additional

Published
2023
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37. Supplementary Figure from Combination Neoantigen-Based Dendritic Cell Vaccination and Adoptive T-Cell Transfer Induces Antitumor Responses Against Recurrence of Hepatocellular Carcinoma

Author

Peng, Sui, primary, Chen, Shuling, primary, Hu, Wei, primary, Mei, Jie, primary, Zeng, Xuezhen, primary, Su, Tianhong, primary, Wang, Wei, primary, Chen, Zebin, primary, Xiao, Han, primary, Zhou, Qian, primary, Li, Bin, primary, Xie, Yubin, primary, Hu, Huanjing, primary, He, Minghui, primary, Han, Yanyan, primary, Tang, Longqing, primary, Ma, Yifan, primary, Li, Xiaoshuang, primary, Zhou, Xiangjun, primary, Dai, Zihao, primary, Liu, Zelong, primary, Tan, Jiehui, primary, Xu, Lixia, primary, Li, Shaoqiang, primary, Shen, Shunli, primary, Li, Dongming, primary, Lai, Jiaming, primary, Peng, Baogang, primary, Peng, Zhenwei, primary, and Kuang, Ming, primary

Published
2023
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38. Data from Combination Neoantigen-Based Dendritic Cell Vaccination and Adoptive T-Cell Transfer Induces Antitumor Responses Against Recurrence of Hepatocellular Carcinoma

Author

Peng, Sui, primary, Chen, Shuling, primary, Hu, Wei, primary, Mei, Jie, primary, Zeng, Xuezhen, primary, Su, Tianhong, primary, Wang, Wei, primary, Chen, Zebin, primary, Xiao, Han, primary, Zhou, Qian, primary, Li, Bin, primary, Xie, Yubin, primary, Hu, Huanjing, primary, He, Minghui, primary, Han, Yanyan, primary, Tang, Longqing, primary, Ma, Yifan, primary, Li, Xiaoshuang, primary, Zhou, Xiangjun, primary, Dai, Zihao, primary, Liu, Zelong, primary, Tan, Jiehui, primary, Xu, Lixia, primary, Li, Shaoqiang, primary, Shen, Shunli, primary, Li, Dongming, primary, Lai, Jiaming, primary, Peng, Baogang, primary, Peng, Zhenwei, primary, and Kuang, Ming, primary

Published
2023
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42. Supplementary Data from Multiomic Analysis Reveals Comprehensive Tumor Heterogeneity and Distinct Immune Subtypes in Multifocal Intrahepatic Cholangiocarcinoma

Author

Chen, Shuling, primary, Xie, Yubin, primary, Cai, Yuhong, primary, Hu, Huanjing, primary, He, Minghui, primary, Liu, Lijuan, primary, Liao, Changyi, primary, Wang, Yuanqi, primary, Wang, Jianping, primary, Ren, Xiaoxue, primary, Zeng, Qianwen, primary, Peng, Hong, primary, Shen, Shunli, primary, Li, Shaoqiang, primary, Li, Dongming, primary, Lai, Jiaming, primary, Peng, Baogang, primary, Ren, Jian, primary, Kuang, Ming, primary, and Peng, Sui, primary

Published
2023
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43. Table S9 from The Influence of Immune Heterogeneity on the Effectiveness of Immune Checkpoint Inhibitors in Multifocal Hepatocellular Carcinomas

Author

Huang, Manling, primary, He, Minghui, primary, Guo, Yu, primary, Li, Heping, primary, Shen, Shunli, primary, Xie, Yubin, primary, Li, Xiaoxing, primary, Xiao, Han, primary, Fang, Lujing, primary, Li, Dongming, primary, Peng, Baogang, primary, Liang, Lijian, primary, Yu, Jun, primary, Kuang, Ming, primary, Xu, Lixia, primary, and Peng, Sui, primary

Published
2023
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44. Figure S1-S17 from The Influence of Immune Heterogeneity on the Effectiveness of Immune Checkpoint Inhibitors in Multifocal Hepatocellular Carcinomas

Author

Huang, Manling, primary, He, Minghui, primary, Guo, Yu, primary, Li, Heping, primary, Shen, Shunli, primary, Xie, Yubin, primary, Li, Xiaoxing, primary, Xiao, Han, primary, Fang, Lujing, primary, Li, Dongming, primary, Peng, Baogang, primary, Liang, Lijian, primary, Yu, Jun, primary, Kuang, Ming, primary, Xu, Lixia, primary, and Peng, Sui, primary

Published
2023
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45. Systemic therapy with or without transcatheter intra-arterial therapies for unresectable hepatocellular carcinoma: a real-world, multi-center study

Author

Pan, Yangxun, Zhu, Xiaodong, Liu, Jianwei, Zhong, Jianhong, Zhang, Wei, Shen, Shunli, Jin, Renan, Liu, Hongzhi, Ye, Feng, Hu, Kuan, Xu, Da, Zhang, Yu, Chen, Zhong, Xing, Baocai, Zhou, Ledu, Chen, Yongjun, Zeng, Yongyi, Liang, Xiao, Kuang, Ming, Song, Tianqiang, Xiang, Bangde, Wang, Kui, Sun, Huichuan, and Xu, Li

Subjects
Immunology, Immunology and Allergy
Published
2023
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46. Distinct single-cell immune ecosystems distinguish true and de novo HBV-related hepatocellular carcinoma recurrences

Author

Chen, Shuling, primary, Huang, Cheng, additional, Liao, Guanrui, additional, Sun, Huichuan, additional, Xie, Yubin, additional, Liao, Changyi, additional, Wang, Jianping, additional, He, Minghui, additional, Hu, Huanjing, additional, Dai, Zihao, additional, Ren, Xiaoxue, additional, Zeng, Xuezhen, additional, Lin, Zhilong, additional, Zhang, Guo-Pei, additional, Xie, Wenxuan, additional, Shen, Shunli, additional, Li, Shaoqiang, additional, Peng, Sui, additional, Kuang, Dong-Ming, additional, Zhao, Qiang, additional, Duda, Dan G, additional, and Kuang, Ming, additional

Published
2023
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48. Targeting tumour-intrinsic N7-methylguanosine tRNA modification inhibits MDSC recruitment and improves anti-PD-1 efficacy

Author

Liu, Haining, primary, Zeng, Xuezhen, additional, Ren, Xuxin, additional, Zhang, Yifan, additional, Huang, Manling, additional, Tan, Li, additional, Dai, Zihao, additional, Lai, Jiaming, additional, Xie, Wenxuan, additional, Chen, Zebin, additional, Peng, Sui, additional, Xu, Lixia, additional, Chen, Shuling, additional, Shen, Shunli, additional, Kuang, Ming, additional, and Lin, Shuibin, additional

Published
2022
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49. A novel protein RASON encoded by a lncRNA controls oncogenic RAS signaling in KRAS mutant cancers

Author

Cheng, Rongjie, primary, Li, Fanying, additional, Zhang, Maolei, additional, Xia, Xin, additional, Wu, Jianzhuang, additional, Gao, Xinya, additional, Zhou, Huangkai, additional, Zhang, Zhi, additional, Huang, Nunu, additional, Yang, Xuesong, additional, Zhang, Yaliang, additional, Shen, Shunli, additional, Kang, Tiebang, additional, Liu, Zexian, additional, Xiao, Feizhe, additional, Yao, Hongwei, additional, Xu, Jianbo, additional, Yan, Chao, additional, and Zhang, Nu, additional

Published
2022
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