466 results on '"Shen, Jingshan"'
Search Results
2. Synthesis and biological evaluation of multimodal monoaminergic arylpiperazine derivatives with potential antidepressant profile
3. Design, synthesis, and biological evaluation of novel 1-amido-2-one-4-thio-deoxypyranose as potential antitumor agents for multiple myeloma
4. The antidepressant-like effect and proposed mechanism of action of TPN672MA, a novel serotonin-dopamine receptor modulator for the treatment of schizophrenia
5. Impurity study of tecovirimat
6. Structure-based development and preclinical evaluation of the SARS-CoV-2 3C-like protease inhibitor simnotrelvir
7. A viral RNA-dependent RNA polymerase inhibitor VV116 broadly inhibits human coronaviruses and has synergistic potency with 3CLpro inhibitor nirmatrelvir
8. Preventive and therapeutic benefits of nelfinavir in rhesus macaques and human beings infected with SARS-CoV-2
9. Cannabidiol exhibits anxiolytic-like effects and antipsychotic-like effects in mice models
10. Discovery of a CB2 and 5-HT1A receptor dual agonist for the treatment of depression and anxiety
11. Glimepiride, a novel soluble epoxide hydrolase inhibitor, protects against heart failure via increasing epoxyeicosatrienoic acids
12. An efficient synthesis of the last step key intermediate for telmisartan via Pd-catalyzed carbonylative cyclization
13. Design, synthesis and biological evaluation of peptidomimetic benzothiazolyl ketones as 3CLpro inhibitors against SARS-CoV-2
14. Efficacy and safety of SIM0417 (SSD8432) plus ritonavir for COVID-19 treatment: a randomised, double-blind, placebo-controlled, phase 1b trial
15. Synthesis, cytotoxicity, and pharmacokinetic evaluations of niclosamide analogs for anti-SARS-CoV-2
16. Design, synthesis and biological evaluation of covalent peptidomimetic 3CL protease inhibitors containing nitrile moiety
17. TPN171H alleviates pulmonary hypertension via inhibiting inflammation in hypoxia and monocrotaline-induced rats
18. Oral remdesivir derivative VV116 is a potent inhibitor of respiratory syncytial virus with efficacy in mouse model
19. Influencing Factors of Anemia in Patients with Diabetic Kidney Disease
20. Synthesis of telmisartan via oxidative cyclization
21. An Improved Iodine-Catalyzed Aromatization Reaction and Its Application in the Synthesis of a Key Intermediate of Cannabidiol
22. Identification of Dihydrobenzofuran Neolignans as Novel PDE4 Inhibitors and Evaluation of Antiatopic Dermatitis Efficacy in DNCB-Induced Mice Model
23. Potency and pharmacokinetics of GS-441524 derivatives against SARS-CoV-2
24. Significant Inhibition of Porcine Epidemic Diarrhea Virus In Vitro by Remdesivir, Its Parent Nucleoside and β-d-N4-hydroxycytidine
25. 9,10-Anhydrodehydroartemisinin Attenuates Experimental Autoimmune Encephalomyelitis by Inhibiting Th1 and Th17 Cell Differentiation
26. SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target
27. Challenges and stepwise fit-for-purpose optimization for bioanalyses of remdesivir metabolites nucleotide monophosphate and triphosphate in mouse tissues using LC–MS/MS
28. Design and development of an oral remdesivir derivative VV116 against SARS-CoV-2
29. An Alternative Approach to Synthesize Sildenafil via Improved Copper-Catalyzed Cyclization.
30. Automated design and optimization of multitarget schizophrenia drug candidates by deep learning
31. Sub-anesthetic and anesthetic ketamine produce different long-lasting behavioral phenotypes (24 h post-treatment) via inducing different brain-derived neurotrophic factor (BDNF) expression level in the hippocampus
32. Oral Simnotrelvir for Adult Patients with Mild-to-Moderate Covid-19
33. Discovery of the Potent Covalent Inhibitor with an Acrylate Warhead for Sars-Cov-2 3cl Protease
34. Impurity Study of Tecovirimat
35. The 5-HT1a Receptor Mediates the Anxiolytic-Like Effects Of Cannabidiol But Does Not Mediate its Effects on the Negative Symptoms of Schizophrenia In Mice Models
36. Repurposing of Rutan showed effective treatment for COVID-19 disease
37. The novel small-molecule TPN10456 inhibits Th17 cell differentiation and protects against experimental autoimmune encephalomyelitis
38. Identification of pyrogallol as a warhead in design of covalent inhibitors for the SARS-CoV-2 3CL protease
39. Characterization of TPN171 metabolism in humans via ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry
40. Rational design of 5-((1H-imidazol-1-yl)methyl)quinolin-8-ol derivatives as novel bromodomain-containing protein 4 inhibitors
41. Combination of miR159 Mimics and Irinotecan Utilizing Lipid Nanoparticles for Enhanced Treatment of Colorectal Cancer.
42. Improved and ligand-free copper-catalyzed cyclization for an efficient synthesis of benzimidazoles from o-bromoarylamine and nitriles.
43. Design, synthesis, and evaluation of novel oxyacanthine derivatives for anti-SARS-CoV-2 activity
44. Discovery of the potent covalent inhibitor with an acrylate warhead for SARS-CoV-2 3CL protease
45. Comparative study on different extraction methods of oil extract from Mentha asiatica Boriss. and optimization of the extraction process by response surface methodology
46. Efficient Large-Scale Process for Tecovirimat via Reactive Distillation for the Preparation of Cycloheptatriene
47. Synthesis and biological evaluation of a series of multi-target N-substituted cyclic imide derivatives with potential antipsychotic effect
48. Nature brings new avenues to the therapy of central nervous system diseases—An overview of possible treatments derived from natural products
49. The complete synthesis of favipiravir from 2-aminopyrazine
50. Synthesis and biological investigation of tetrahydropyridopyrimidinone derivatives as potential multireceptor atypical antipsychotics
Catalog
Books, media, physical & digital resources
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.