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In view of the problem that peanut harvesting in hilly areas mainly involves fresh food, and that the peanut-picking purity rate is low and there is high breakage in the peanut-harvesting process, key components such as the picking system of a fresh-peanut-picking crawler combine harvester, the picking tooth, and the concave screen were designed, and ANSYS Workbench 2020 software was used to check the reliability of the picking roller under working conditions in hilly areas. In the process of equipment operation, the picking purity rate and breakage rate were the main evaluation indexes, and the Box–Behnken test method was used to study the speed of the peanut-picking roller, the feeding amount, and the picking gap as the test factors. The results showed that the picking purity rate is 98.95%, with an error margin of 0.98%, compared to the predicted value under the conditions of 342 r/min speed, 0.75 kg/s feeding amount, and 32 mm picking gap. The breakage rate is 4.23% and the error is 0.4% compared with the predicted value, indicating that the optimized model is reliable and predictive. This study provides a theoretical basis for the optimal design of the peanut-picking system of peanut-picking combine harvesters in hilly areas. [ABSTRACT FROM AUTHOR]

Waste plastic film often contains an abundance of impurities, such as crop stems and soil. To address this issue, a toothed-plate single-roller crushing device for waste plastic film was developed. By analyzing the movement and force pattern of the film, the feeding speed, the number of toothed plates, and the crushing roller rotation speed were used as test factors, and the size qualification rate and the impurity content of the crushed film were used as test indexes. Through a Box–Behnken test design, regression analysis, and ANOVA, a model between factors and indexes was established. The results showed that the size qualification rate and the impurity content of the crushed film were 82.55% and 9.57%, and the errors in the prediction and test values were 6.14% and 8.38%, which proved them to have good reliability. The findings of this study provide essential technical and equipment support for the resource recovery of waste plastic films. [ABSTRACT FROM AUTHOR]

This study designed a control system for the automatic unloading and replenishment of baskets based on the cooperative detection of photoelectric sensors and pressure sensors based on analyzing the structure of the 4UM-120D electric leafy vegetable harvester. The goal of this study was to increase the operation efficiency of leafy vegetable harvesters and decrease the work intensity of operators. A control system for the automatic unloading and replenishment of baskets based on the cooperative detection of a photoelectric sensor and pressure sensor was designed and constructed after an analysis of the operating principle and system components of automatic basket unloading and basket replenishment control at the rear of the harvester. The bench test results showed that the bottom photoelectric sensor and top photoelectric sensors 1 and 2 on the touch screen were not lit and the pressure sensor value was displayed as −0.00075531 kg, after pressing the system start button on the touch screen. On the touch screen, only the basket feeding motor was on: the transverse conveyor motor and the basket unloading motor were not, indicating that there was no collection basket on the unloading basket conveyor belt at this time and that the basket feeding motor was conveying an empty basket to the unloading basket conveyor belt. At 26 s, on the touch screen, only the top photoelectric sensor 2 was not on: the top photoelectric sensor 1 and the bottom photoelectric sensor were on and the pressure sensor value was shown as 1.38488 kg. Only the transverse conveyor motor lit up on the touch screen, the basket unloading motor and the basket feeding motor did not light up, indicating that the leafy vegetables temporarily stored in the transverse conveyor belt started to fall into the collection basket at this time and had not yet reached the expected capacity of the collection basket. At 43 s, the bottom photoelectric sensor and top photoelectric sensors 1 and 2 were lit on the touch screen and the pressure sensor value was shown as 2.37229 kg. On the touch screen, only the basket unloading motor lit up: the transverse conveyor motor and the basket feeding motor were not lit up, indicating that the collection basket capacity had reached the expected capacity at this time and the unloading was in progress. At 83 s, the bottom photoelectric sensor and top photoelectric sensors 1 and 2 were not lit on the touch screen and the pressure sensor value was displayed as −0.0040102 kg. On the touch screen, only the basket feeding motor lit up: the transverse conveyor motor and the basket unloading motor did not light up, indicating that the collection basket with the expected capacity had been unloaded to the ground, and the basket feeding motor was transporting empty baskets to the basket unloading conveyor belt. Through bench simulation tests, it was determined that the control system for the automatic unloading and replenishment of baskets based on the cooperative detection control strategy of the photoelectric sensor and pressure sensor reduced the probability of misjudgment and misoperation and improved system performance. This was conducted with the probability of system misjudgment and misoperation serving as the main evaluation index. The simulation results demonstrated that the control system for the automatic unloading and replenishment of baskets based on a photoelectric sensor and pressure sensor cooperative detection control strategy could be error-free judgment and avoid misoperation, effectively improving the stability, accuracy, and rapidity of the system. The study's findings could suggest a strategy to lessen the workload of operators and increase the operational effectiveness of harvesters for leafy vegetables. [ABSTRACT FROM AUTHOR]

The aim of the study is to evaluate the practicability and therapeutic efficacy of iodine seeds implantation percutaneously for portal vein tumor thrombosis (PVTT) in patients with hepatocellular carcinoma (HCC). Nineteen patients with HCC accompanied with PVTT received ultrasound-guided implantation of 8-30 iodine seeds, 8 mm apart within the portal vein tumor thrombi. The patients were followed up postoperatively for a period of 3-22 months. The successful rates of the procedure, postoperative changes of liver and renal function, hemogram, complications and therapeutic response were monitored. I seeds were successfully implanted in the portal veins in all patients without serious complications. During the follow-up period, the portal vein tumor thrombi all shrunk obviously. Percutaneous implantation of iodine seeds into the portal vein is an effective and safe treatment for PVTT accompanying HCC. [ABSTRACT FROM AUTHOR]

This study aimed to identify the key pathways and to explore the mechanism of sorafenib in inhibiting hepatocellular carcinoma (HCC). The gene expression profile of GSE33621, including 6 sorafenib treated group and 6 control samples, was downloaded from the GEO (Gene Expression Omnibus) database. The differentially expressed genes (DEGs) in HCC samples were screened using the ΔΔCt method with the homogenized internal GAPDH. Also, the functions and pathways of DEGs were analyzed using the DAVID. Moreover, the significant pathways of DEGs that involved in HCC were analyzed based on the Latent pathway identification analysis (LPIA). A total of 44 down-regulated DEGs were selected in HCC samples. Also, there were 84 biological pathways that these 44 DEGs involved in. Also, LPIA showed that Osteoclast differentiation and hsa04664-Fc epsilon RI signaling pathway was the most significant interaction pathways. Moreover, Apoptosis, Toll-like receptor signaling pathway, Chagas disease, and T cell receptor signaling pathway were the significant pathways that interacted with hsa04664. In addition, DEGs such as AKT1 (v-akt murine thymoma viral oncogene homolog 1), TNF (tumor necrosis factor), SYK (spleen tyrosine kinase), and PIK3R1 (phosphoinositide-3-kinase, regulatory subunit 1 (alpha)) were the common genes that involved in the significant pathways. Several pathway interaction pairs that caused by several downregulated genes such as SYK, PI3K, AKT1, and TNF, were identified play curial role in sorafenib treated HCC. Sorafenib played important inhibition roles in HCC by affecting a complicate pathway interaction network.