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In this paper, a simple and one-pot synthetic strategy was established to prepare copper nanoclusters by using tannic acid as the template and ascorbic acid as the reducing agent. The tannic acid-capped copper nanoclusters (Cu NCs@TA) displayed excitation and emission peaks around 365 and 435 nm with fluorescence quantum yield of 9.8%. Based on the inner filter effect and static quenching mechanisms, the Cu NCs@TA was used to selectively and sensitively determine the chlortetracycline. Under the optimal detection conditions, the excellent linear range of 0.5-200 μM was obtained and the limit of detection (LOD) was gained as 0.084 μM. The satisfactory recoveries of 94.4%~103.1% in real bovine serum samples indicated that this platform could be employed in practical test of chlortetracycline.

This paper gets a further study to cladding of Ni-based Titanium Carbide in the surface of die steel of 718, This paper introduces the effect of laser process parameters on the titanium carbide and nickel solid solution and cemented carbide in cladding layer; on that basis, this paper studied the effect of the different of powder paving thickness, laser power and scanning velocity and other parameters on microstructure and properties of cladding layer. By controlling the powder-bed depth, using suitable laser cladding power and scanning speed, we can get the cladding layer of compact structure, no holes or no cracks. Experiments were carried out to get suitable process parameters, and analyzed its mechanism. It has certain significance guiding to improve the laser cladding of 718 die steel quality

To analyze the genetic effect of the abnormal chromosome karyotype, we summarized and studied the clinical data of the new abnormal karyotypes diagnosed at the Guangxi Zhuang Autonomous Region Women and Children Care Hospital from January 2009 to July 2012. The samples were cultured routinely for the karyotype analysis using G banding and C banding. Chromosomal aberrations were named according to the International System for Human Cytogenetic Nomenclature (ISCN 2009). Among tested samples, 105 new human abnormal karyotypes were identified (86 reciprocal translocation, 10 chromosomal inversion, six derivative chromosome, one duplication, one isochromosome, one partial trisomy and monosomy). The results suggest that chromosomal abnormalities were a major cause of miscarriage, infertility, congenital abnormalities, mental retardation and amenorrhea in humans.

The research of the control system of automatic feeding machine in the present paper can be applied in different mechanical designs – from simple key-press input of cycling days, multiple time intervals and the feeding amount to setting steps of numbers of stepping motor via the control of SMC by time setting. This not only realizes the objective of “fixed-time” and “fixed-quantity” feeding, but also solves the problems of serious leaking, high failure rate, and loud noises during the process of using warehouse-type feeding machines, which brings favorable economic and social benefits for enterprises.

A new method of triangulation for large scale scattered 3D points is proposed. This method is based on the available CAD model, with the thought of DC(divide and conquer).Alignment between the data and the CAD model, registration which establishes correspondence between the data points and those on the CAD trimmed NURBS surface entities;2D-Delaunay triangulation, performed on the corresponding points in the parametric domains(u, v)of each entity, application of the connectivity structure to the 3D data points for each mesh patch; Elimination of redundant triangles of each 3D mesh patch and stitching of patches together. Unlike many other methods, it is not constrained by certain types of measurement distribution or object shape. The experimental results testify that the approach is feasible and efficient.

The paper presents a method of the serial communication codes of the testing interface card by using the serial monitor software and ROBO Pro graphical software, and the research on the movement control system is based on Fischertechnik interface. The system software with Windows style is developed by using the serial communication function of advanced programming language VB6.0. The serial interface program through the MSComm control of VB6.0, and the status of Fischertechink interface could be detected through the received communication codes, sending communication codes to control the movement of mode.

To investigate the prevalence of hypertension and the relationship between hypertension and obesity in children and adolescents aged 6-18 years in Nanning, Guangxi Province, China.A stratified cluster random sampling method was adopted in Nanning to select 7 893 children and adolescents aged 6-18 years as research subjects. Questionnaire surveys were conducted, and blood pressure, height, weight, and other indicators of growth and development were measured.An increasing trend with age for both systolic blood pressure (SBP) and diastolic blood pressure (DBP) was observed. Detection rates of hypertension, high SBP (HSBP) and high DBP (HDBP) were 6.58%, 4.02% and 3.81%, respectively. The detection rates of hypertension and HSBP in boys were significantly higher than in girls (Plt;0.05). The detection rates of hypertension in normal, overweight and obesity groups were 3.87%, 9.84% and 19.23%, respectively. The obesity group showed the highest detection rates for hypertension, HSBP and HDBP, followed by the overweight group and normal group. Compared with that in the normal group, the odds ratios (95% CI) for hypertension in the overweight and obesity groups were 2.71 (1.69-5.96) and 5.91 (3.46-7.63), respectively. Blood pressure showed a positive correlation with age, height, weight and BMI (Plt;0.01).The present study provides with the current information and characteristics of blood pressure of children and adolescents aged 6-18 years in Nanning, Guangxi. Blood pressure is correlated with gender, age, height, weight and BMI. Obesity is positively correlated with the prevalence of hypertension and the risk of hypertension increases with body weight.

To study the relationship between abnormal karyotypes and clinical phenotypes among children in genetic counseling in Guangxi Zhuang Autonomous Region, China.We studied 601 children who visited Guangxi Zhuang Autonomous Region Women and Children Care Hospital for genetic counseling between January 2009 and July 2012. Blood samples were cultured routinely for karyotype analysis with G banding as well as clinical analysis.Out of 601 patients, 329 (54.7%) had chromosomal abnormalities, and 8 new abnormal human karyotypes were found. Among 329 children with abnormal karyotypes, 317 (96.4%) had an abnormal number of chromosomes, and 12 (3.6%) had abnormal chromosomal structure. Abnormal karyotypes were clinically manifested by Down's syndrome (74.5%), growth retardation (10.9%), and mental retardation (3.0%).Eight rare abnormal karyotypes were found in the study, providing new resources for the genetic studies and etiological analysis of growth retardation, mental retardation, gonadal dysgenesis, and multiple congenital anomalies in children.

To analyze clinical manifestations and gene mutations in a child with severe short stature, explore its molecular mechanism and further clarify the diagnostic procedure for short stature.We observed clinical characteristics of a patient with short stature and did diagnostic examinations, assessed the function of GH-IGF-1 axis, and surveyed its family members.Genomic DNA was extracted from peripheral blood, GHR, IGFALS, STAT5b and GH1 gene were amplified by PCR for sequencing, including exons and splicing areas.The patient presented symmetrical short stature (height -8.2 SDS) and facial features, and other congenital abnormalities.It displayed non-growth hormone deficiency. The baseline value of GH was 21 µg/L, and the peak was 57.9 µg/L. The value of IGF-1 was less than 25 µg/L, and the IGFBP-3 less than 50 µg/L. And IGF-1 generation test showed no response. There was no similar patients in the family members.Sequencing of GHR in the patient revealed a homozygous point mutation (c.Ivs6+1GA), and her father and mother had the same heterozygous mutation. The same mutation was not identified for her sister.No other candidate gene was found.As the result of combined clinical characteristics and lab examinations, as well as gene detection, the case was diagnosed with Laron syndrome and GHR gene mutation is the molecular mechanism.We should explicit the etiological diagnosis for short stature, and avoid missed diagnosis and misdiagnosis.

To explore the prevalence of pulmonary surfactant associated pathway genes functional variants in Chinese population.Using a cohort of 258 mixed ethnic population of Han and Zhuang, we pooled DNA samples from 146 term male infants and 112 term female infants and then used an Ill umina next generation sequencing platform to perform the complete exonic resequencing in 6 target genes:surfactant protein-B (SFTPB), surfactant protein-C (SFTPC), ATP-binding cassette transporter A3 (ABCA3), lysophospholipid acyltransferase 1 (LPCAT1), choline phosphotransferase 1 (CHPT1), phosphate cytidylyltransferase 1, choline, beta (PCYT1B). Collapsing methods was used to determine the functional allele frequency.(1) Altogether, 128 variants were found, including 44 synonymous variants, 66 nonsynonymous variants and 18 insertions-deletions. Of these, 28 variants were predicted to alter protein function. Two of these variants were seen twice, the rest variants were only seen once, for a total of 30 functional alleles; (2) ABCA3 had the most functional variants in both male and female groups with the minor allele frequencies of 0.014 (1.4%) and 0.04 (4%), respectively. The total functional allele frequencies of 6 genes were 0.041 (4.1%) and 0.08 (8%) in the two groups, respectively (P = 0.06).(1) Functional variants in pulmonary surfactant associated pathway genes are present in the mixed Han-Zhuang population. (2) ABCA3 contained the most functional variants suggesting that ABCA3 could contribute significantly to neonatal respiratory distress syndrome and other lung disease.

To investigate the lipid levels of Han ethnicity Chinese children at school-age, to provide objective data for the formulation of prevention and management strategy regarding dyslipidemia among children and adolescents.20 191 children (with 10 669 boys and 9522 girls) aged 7 to 16 years old from 6 representative geographical areas, including Beijing, Tianjin, Hangzhou, Shanghai, Chongqing and Nanning, were surveyed in a randomly selected clustered sample in China. Data on fasting blood triglyceride (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C) levels were measured. Non-high-density lipoprotein cholesterol (non-HDL-C) levels were calculated with data collection, entry, and collation were under the same criteria.(1) In the 7 - 16 year-old group, TG (P(95)) fluctuated between 1.26 mmol/L and 1.88 mmol/L, while TC (P(95)) was between 4.80 mmol/L and 5.46 mmol/L. LDL-C (P(95)) was between 2.67 mmol/L and 3.27 mmol/L while non-HDL-C (P(95)) was between 3.36 mmol/L and 3.91 mmol/L, suggesting that age did not seem to be an affecting factor for the lipid level (P0.05). The level of HDL-C (P(5)) fluctuated between 1.08 mmol/L and 0.83 mmol/L, and the dependability analysis on HDL-C and age showed statistically significant difference (P0.01, r = -0.274). (2) In the 7 - 9 year-old group, the levels of TG, TC, LDL-C and non-HDL-C of boys were lower but the HDL-C level was higher than in girls. However, in the 10-16 year-old group, the levels of five lipids of boys were all lower than in girls, with all the differences statistically significant (P0.05). (3) The levels of TG, TC, LDL-C and non-HDL-C in the obese group were significantly higher than those in non-obesity group, as HDL-C was significantly lower than in non-obese group (P0.01). Incidence rates of single and multiple dyslipidemia in obese group were significantly higher than in non-obese group (P0.01). (4) Grouped by region, the abnormal rates of TG were descending, with the ranking as North (10.4%), Midwest (9.7%) and East (8.3%), while the abnormal rates of TC were descending with the ranking as Midwest (6.0%), North (5.2%) and East (4.8%). The abnormal rates of LDL-C were descending as the ranking of North (3.1%), East (2.6%) and Midwest (0.9%), with the abnormal rates of non-HDL-C were descending as Midwest (6.5%), North (4.2%) and East (3.6%). The abnormal rates of HDL-C were descending as Midwess (14.2%), North (5.7%) and East (5.5%). All the differences in the above-said items were statistically significant (P0.05). (5) According to the standards of hyperlipidemia formulated by the American Academy of Pediatrics, the incidence rates of abnormal TG, TC, LDL-C, non-HDL-C, HDL-C were 9.4%, 5.4%, 2.2%, 4.8%, 8.6% respectively.(1) Levels of lipids were affected by many factors, but age was not one of them in children and adolescents. However, HDL-C was declining along with the increase of age, to some extent. (2) Girls had a relatively protective tendency through the increasing HDL-C level when they entered the puberty years. (3) Lipids levels in non-obese group were significantly better than the obese group. (4) The lipids levels of children and adolescents in the Eastern region of the country were better than that in the northern and mid-western areas.

To provide data as age-gender dependent mean, standard deviation and percentile on height, weight, waist circumference (WC), hip circumference (HC), body mass index (BMI), waist hip ratio (WHR), waist to height ratio (WHtR) among 7-16 year-olds Chinese children and adolescents, towards setting up diagnostic criteria on metabolic syndrome for them.A representative sample involving 22,197 children and adolescence aged 7 to 16 years were randomly surveyed and they were from 6 representative geographical areas, including Beijing, Tianjin, Hangzhou, Shanghai, Chongqing and Nanning. A total of 21 858 had available data, with male/female ratio as: 11,460/10,398. Using the standard methods, we measured height, weight, WC, HC, BMI, WHtR and other data in all age groups. Physique indexes among different geographic regions (North, Mid-west and East) were compared.(1) Both male and female showed an increasing trend of height, weight, waist circumference, hip circumference and BMI along with the increase of age. WHR of girls decreased gradually from 0.84 to 0.76 went from 7 to 16 years old while WHR of boys changed from 0.87 to 0.81 accordingly. (2) WHtR was rarely affected by age. It fluctuated between 0.42-0.43 in all girls and 0.44-0.45 in boys less than 11 years. WHtR of boys older than 12 years showed a slight decline from 0.45 to 0.42 of WHtR. (3) The average height, weight, BMI of children and adolescents from the northern regions (Beijing, Tianjin) were significantly higher than that of the mid-western (Chongqing, Nanning) and the eastern regions (Shanghai, Hangzhou) (P0.001), while those from the mid-western region were slightly higher than that of the eastern region (P0.05) in each of the age group.Reference values and percentile curves for WC and WHtR of Chinese children and adolescents were provided. For the assessment of central obesity. WHtR had the advantages of relative stability and small degree of variation and rarely affected by age and gender, when compared with WC, and could be used as an simple index to reflect the central obesity of children and adolescents.

To investigate the association between obesity and prevalence of metabolic syndrome (MS) with its associated risk factors, in children and adolescents.A stratified random sampling method was used to select 7893 students from 6 to 18 years of age from 14 out of 396 primary and secondary schools in Nanning city. All the students had undergone physical examination and blood tests including the following risk factors related to metabolic syndrome: fasting blood glucose (FBG), total cholesterol (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), alanine amino shift enzyme (ALT), aspartic acid amine shift enzyme (AST) and fasting insulin (FINS). The homeostasis model assessment insulin resistance index (HOMA-IR) was also measured.(1) The prevalence rate of MS in normal group was 0.57%. In both the overweight and obesity groups, the prevalence rates of MS were 4.53% and 26.80%, respectively. (2) These indices in obesity group were higher than other two groups (P0.05). The result of overweight group was higher than normal group (P0.05). (3) Waist circumference (OR = 1.087, 95%CI: 1.033 - 1.143), SBP (OR = 1.073, 95%CI: 1.032 - 1.116), FBG (OR = 1.394, 95%CI: 1.568 - 3.423), TG (OR = 3.213, 95%CI: 1.410 - 7.319) and HDL-C (OR = 0.001, 95%CI: 0.000 - 0.012) were detecting indices which had statistically significant with MS in binary logistic regression analysis.Metabolic syndrome and obesity were closely related in children and adolescents while its prevalence and risk factors increased with the severity of obesity.

To study the association of alanine aminotransferase (ALT) with overweight or obesity in children.A total of 2889 healthy children and 702 overweight or obese children aged from 7 to 18 years who had received a physical examination were enrolled. Height, body weight, waist circumference, and blood pressure were measured, and the biochemical indicators including blood glucose, blood lipids, ALT, and insulin were detected. The insulin resistance index were calculated.The ALT level was significantly higher in boys than in girls. Along with the increase of BMI, the ALT level increased in the normal, overweight, and obese groups in both boys and girls. ALT was correlated with BMI, waist circumference, triglyceride, and insulin resistance index. Among the overweight or obese children, the boys with the increased ALT level had higher BMI, waist circumference, blood pressure, triglyceride, low density lipoprotein and insulin resistance index than the boys with normal ALT level (P0.05); the girls with the increased ALT level had higher waist circumference, blood pressure and insulin resistance index and lower high density lipoprotein than the girls with normal ALT level (P0.05).ALT is correlated with overweight and obesity and metabolic disorders caused by overweight and obesity such as dyslipidemia and insulin resistance.

In this paper, the single-side asymmetry cycloid-pin-tooth arc rotor of compressor is studied. It analyses the Curve equation of single-side asymmetry cycloid-pin-tooth arc rotor of compressor. Meanwhile it carries on the parametric designs of the single-side asymmetry cycloid- pin-tooth arc rotor of compressor under Visual C++ development environment. The parametric modeling for rotor is implemented by Pro/e and the application program is written by Pro/TOOLKIT at the same time. The new model of compressor rotor is regenerated through inputting main parameters directly in man-machine conversation dialog box. Thus it can improve design efficiency of compressor rotor, and it will shorten the development cycle of production and reduce the designer's repeated work.

Based on the analysis of current triangulation method, a new 3D triangulation method based on boundary extension is proposed. Binning method is first applied to reduce the original point cloud into thin data, then the triangulation processes start with selected seed triangles, the triangular meshes extend outward by continuously linking the most suitable points to them along the boundary edges of the meshed area. Data points of some non- convex complex object surface such as object with interior holes can be directly triangulated without manually dividing it into several convex patches. The application results indicate that this approach is feasible and efficient in modeling of 3D point cloud.

To study the effects of treatment with gonadotropin-releasing hormone analogs (GnRHa) on final height, weight and pubertal development in girls with central precocious puberty.Twenty-six girls with central precocious puberty were treated with GnRHa for an average of 19.2+/- 8.4 months. Pretreatment and posttreatment predicted adult heights (PAH) were evaluated based on the Bayley-Pineau table. The patients, heights and weights were measured monthly. Bone age (BA) was evaluated using Greulich-Plyle. Height standard deviation score for BA [HtSDS (BA)] was measured. After discontinuation of treatment, the patients were followed-up for the observation of height, weight, BA and menstruation.Final height averaged 158.0+/- 4.0 cm in the 26 girls, which was greater than their target height (155.3+/- 4.4 cm; P0.01) and consistent with their posttreatment PAH (158.4+/- 5.2 cm). The final height was positively corrrelated with initial height, PAH and HtSDS(BA). There was a positive correlation in the body mass index before and after treatment (r=0.724, P0.01). Menarche occurred 13.2+/- 6.1 months after discontinuation of treatment, with a mean menarche age of 12.2+/- 0.7 years.GnRHa may increase final height in girls with central precocious puberty. Their final heights may be correlated with their initial heights and PAH. The pubertal development after GnRHa treatment in girls with central precocious puberty may be matched with normal children.

With the development of industrial Ethernet technology, Ethernet has infiltrated into the control layer and equipment layer of control system network. However, a large number of industrial site equipment is not equipped with network interfaces, and they perform communication through serial ports, so they fail to be connected to Ethernet directly. With the development of technology, 32-bit microprocessor has become the mainstream of embedded market application. In the article, the 32-bit microprocessor S3C2410 is chosen to be the embedded interface controller developed as main chip to realize the conversion between serial port data and Ethernet data. Without changing the original equipment, network interface is added so that the conventional serial port equipment can be connected to the Internet through standard TCP/IP protocol.

In order to apply Fuzzy PID control theory in thermoforming machine, people must make discourse analysis for the temperature control system of the thermoforming. Before finishing the Fuzzy PID control of thermoforming machine, they also need to apply fuzzy controlling table in control system. The coming of fuzzy controlling table attribute the success to the use of fuzzy mathematics in automation. The selection of membership function, the formula of fuzzy rule, the process of fuzzy inference are based upon the use of fuzzy mathematics. the process of fuzzy inference can be simulated by the simulink module of MATLAB.