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Key Clinical Message: We present a rare case of a female pelvic solitary fibrous tumor unsuccessfully resected using single‐port laparoscopy, requiring conversion to laparotomy. Although the resection was successful, the surgical approach could have been improved. For large tumors, minimally invasive results are possible with flexible choices of equipment and incision position. [ABSTRACT FROM AUTHOR]

Abstract: High resolution absorption spectra of the (4, 20) band in the second negative system (A 2 Πu –X 2 Πg ) of O2 + cation were measured and analyzed in the range of 11900–12300cm–1 via optical heterodyne velocity modulation spectroscopy. Precise molecular constants of the levels involved were obtained by a nonlinear least-squares fitting procedure combining with our previous spectra of the (4, 19) and (6, 20) bands. [Copyright &y& Elsevier]

Abstract: The (1,0) band in the b 4Σ−–a 4Π5/2 system of the SO+ cation ion has been observed in the range of 12600–12800cm−1 using optical heterodyne velocity modulation spectroscopy in an AC glow discharge of He/SO2 mixture. Rotational analysis results in close to a three orders of magnitude improvement in the molecular constants. [Copyright &y& Elsevier]

Background: Abnormal stromal-epithelial cell communication is a pathogenic mechanism in endometriosis, and metformin can modulate it. Insulin-like growth factor binding protein-1 (IGFBP1) plays a role in endometriosis, but the exact mechanism is unknown. IGFBP1 is reportedly a downstream target of metformin in some diseases. We aimed to investigate the role of IGFBP1 in endometriosis development, whether it is associated with abnormal communication, and whether metformin affects IGFBP1 expression., Methods: Patients who underwent surgical treatment for endometriosis or other diseases were enrolled. Ten patients with ovarian-type endometriosis and eight patients each who underwent surgical treatment for other lesions with or without endometriosis were selected, and their tissues taken for cell proliferation, western blotting, polymerase chain reaction, and knockdown experiments., Results: Ectopic and eutopic stromal cells (EcSCs and EuSCs) lost their ability to inhibit epithelial cell proliferation, and IGFBP1 expression was downregulated in both groups of stromal cells compared to that in normal stromal cells (NSCs; 1.09 vs. 0.25, p  = .0002 1.09 vs. 0.57, p  = .0029). In an EcSC IGFBP1 overexpression model, the ability of EcSCs to inhibit epithelial cell proliferation was enhanced (EdU positivity decreased from 38% to 25%, p  = .0001). Furthermore, adenosine 5'-monophosphate-activated protein kinase (AMPK) phosphorylation was downregulated in EcSCs and EuSCs compared to that in NSCs (0.99 vs. 0.42, p  = .0006/0.99 vs. 0.57, p  = 0.0032). Treatment of EcSCs with metformin increased AMPK phosphorylation (0.47 vs. 1.04, p  = .0107) while upregulating IGFBP1 expression (0.69 vs. 1.01, p  = .0164), whereas pre-treatment with an AMPK phosphorylation inhibitor abrogated metformin-induced IGFBP1 upregulation., Conclusions: IGFBP1 mediates aberrant stromal-epithelial communication in endometriosis. Metformin can upregulate IGFBP1 expression in EcSCs by activating AMPK, and upregulated IGFBP1 enhances the inhibition of epithelial cell proliferation. IGFBP1 is expected to be a therapeutic target for endometriosis.