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22 results on '"Shao, Qiyuan"'

7. Structures and implications of the C962R protein of African swine fever virus

Author

Shao, Zhiwei, primary, Su, Shichen, additional, Yang, Jie, additional, Zhang, Weizhen, additional, Gao, Yanqing, additional, Zhao, Xin, additional, Zhang, Yixi, additional, Shao, Qiyuan, additional, Cao, Chulei, additional, Li, Huili, additional, Liu, Hehua, additional, Zhang, Jinru, additional, Lin, Jinzhong, additional, Ma, Jinbiao, additional, and Gan, Jianhua, additional

Published
2023
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10. Crystal structures and identification of novel Cd2+-specific DNA aptamer

Author

Liu, Hehua, primary, Gao, Yanqing, additional, Mathivanan, Johnsi, additional, Armour-Garb, Zev, additional, Shao, Zhiwei, additional, Zhang, Yixi, additional, Zhao, Xin, additional, Shao, Qiyuan, additional, Zhang, Weizhen, additional, Yang, Jie, additional, Cao, Chulei, additional, Li, Huili, additional, Sheng, Jia, additional, and Gan, Jianhua, additional

Published
2023
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18. Structure-guided development of Pb2+-binding DNA aptamers.

Author

Liu, Hehua, Gao, Yanqing, Mathivanan, Johnsi, Shen, Fusheng, Chen, Xi, Li, Yangyang, Shao, Zhiwei, Zhang, Yixi, Shao, Qiyuan, Sheng, Jia, and Gan, Jianhua

Subjects
APTAMERS, QUADRUPLEX nucleic acids, DNA, HUMAN ecology, CRYSTAL structure, THROMBIN
Abstract

Owing to its great threat to human health and environment, Pb2+ pollution has been recognized as a major public problem by the World Health Organization (WHO). Many DNA aptamers have been utilized in the development of Pb2+-detection sensors, but the underlying mechanisms remain elusive. Here, we report three Pb2+-complexed structures of the thrombin binding aptamer (TBA). These high-resolution crystal structures showed that TBA forms intramolecular G-quadruplex and Pb2+ is bound by the two G-tetrads in the center. Compared to K+-stabilized G-quadruplexes, the coordinating distance between Pb2+ and the G-tetrads are much shorter. The T3T4 and T12T13 linkers play important roles in dimerization and crystallization of TBA, but they are changeable for Pb2+-binding. In combination with mutagenesis and CD spectra, the G8C mutant structure unraveled that the T7G8T9 linker of TBA is also variable. In addition to expansion of the Pb2+-binding aptamer sequences, our study also set up one great example for quick and rational development of other aptamers with similar or optimized binding activity. [ABSTRACT FROM AUTHOR]

Published
2022
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19. Sensing Characteristics of Near-Infrared Band Based on New Photonic Crystal Fiber

Author

张文 Zhang Wen, 白冰冰 Bai Bingbing, 陈聪 Chen Cong, 王浩然 Wang Haoran, 陈灿灿 Chen Cancan, 张砚曾 Zhang Yanzeng, 刘海 Liu Hai, and 邵齐元 Shao Qiyuan

Subjects
Materials science, business.industry, Near-infrared spectroscopy, Optoelectronics, Electrical and Electronic Engineering, business, Atomic and Molecular Physics, and Optics, Electronic, Optical and Magnetic Materials, Photonic-crystal fiber
Published
2021

20. High-Sensitivity Temperature Measurement Based on SPR in Gold-PDMS-Coated Photonic Crystal Fiber

Author

刘海 Liu Hai, 张砚曾 Zhang Yanzeng, 陈聪 Chen Cong, 王浩然 Wang Haoran, 邵齐元 Shao Qiyuan, and 白冰冰 Bai Bingbing

Subjects
Materials science, business.industry, Optoelectronics, Sensitivity (control systems), Electrical and Electronic Engineering, business, Temperature measurement, Atomic and Molecular Physics, and Optics, Electronic, Optical and Magnetic Materials, Photonic-crystal fiber
Published
2020

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