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15 results on '"Shamma, Fayek N."'

2. HLA-DQ-beta-57 in Hispanic patients with insulin-dependent diabetes mellitus

Author

Lee, Grace, Shamma, Fayek N., Diamond, Michael P., and Lee, John T.D.

Subjects
Major histocompatibility complex -- Physiological aspects, Type 1 diabetes -- Physiological aspects, Disease susceptibility -- Physiological aspects, Hispanic American women -- Health aspects, HLA histocompatibility antigens -- Physiological aspects, Health
Published
1992

7. Reply

Author

Shamma, Fayek N., primary and Schwartz, Lisa B., additional

Published
1993
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13. Preliminary Evidence That GnRH Has the Properties of a Growth Hormone-Releasing Factor In Vivo in the Rat.

Author

Penzias, Alan S., Goodman, Stephanie R., Rossi, Gabriele, Shamma, Fayek N., Aten, Raymond F., Behrman, Harold R., and Jones, Ervin E.

Abstract

Objective:We investigated whether GnRH has the properties of a growth hormone-releasing factor in vivo in a mammalian species.Methods:Sexually mature female Sprague-Dawley rats were prepared for in vivo dynamic hormone testing. The rats were assigned to one of four groups: I) GnRH, II) apomorphine and GnRH, III) somatostatin and GnRH, or IV) saline control. Blood samples were drawn at 0, 30, 60, 90, and 120 minutes after treatment. Growth hormone (GH) and LH were measured by radioimmunoassay. Results were analyzed using repeated-measures analysis of variance, Student t test, and comparisons of the area under the curve where appropriate.Results:Gonadotropin-releasing hormone caused a marked rise in both GH and LH levels as a function of time. Apomorphine caused a significant blunting of the LH response to GnRH but did not blunt the GnRH-induced rise in GH. Somatostatin blocked the GnRH-induced rise in GH but did not block the increase in LH. In saline-treated controls, neither the GH nor LH levels exhibited a statistically significant variance over the 2-hour test period.Conclusions:Gonadotropin-releasing hormone appears to have the properties of a growth hormone-releasing factor. [ABSTRACT FROM PUBLISHER]

Published
1995
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15. The effect of Norplant**Norplant, Wyeth-Ayerst Laboratories, Philadelphia, Pennsylvania.on glucose metabolism under hyperglycemic hyperinsulinemic conditions††Presented at the 40th Annual Meeting of the Society for Gynecologic Investigation, March 31 to April 3, 1993, Toronto, Ontario, Canada.

Author

Shamma, Fayek N., Rossi, Gabriel, HajHassan, Lamia, Penzias, Alan S., Connoly-Diamond, Meredith, Jones, Ervin, and Diamond, Michael P.

Abstract

To assess the impact of a levonorgestrel-releasing implant contraceptive (Norplant; Wyeth-Ayerst Laboratories, Philadelphia, PA) on glucose metabolism.

Published
1995
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