Search

Your search keyword '"Shakeel, Sadia"' showing total 212 results
Start Over Author "Shakeel, Sadia"
212 results on '"Shakeel, Sadia"'

16. The impact of diabetes mellitus on the emergence of multi-drug resistant tuberculosis and treatment failure in TB-diabetes comorbid patients: a systematic review and meta-analysis

Author

Rehman, Anees ur, primary, Khattak, Mahnoor, additional, Mushtaq, Usman, additional, Latif, Muhammad, additional, Ahmad, Imran, additional, Rasool, Muhammad Fawad, additional, Shakeel, Sadia, additional, Hayat, Khezar, additional, Hussain, Rabia, additional, Alhazmi, Ghaidaa Ali, additional, Alshomrani, Afnan Owedah, additional, Alalawi, Mohammed Ibrahim, additional, Alghamdi, Saleh, additional, Imam, Mohammad Tarique, additional, Almarzoky Abuhussain, Safa S., additional, Khayyat, Sarah M., additional, and Haseeb, Abdul, additional

Published
2023
Full Text
View/download PDF

20. Antibiotic Stewardship: A Handshaking Strategy Among Physicians and Pharmacists to Improve therapeutic Outcomes in Hematology-Oncology.

Author

Ali, Kashif, Shakeel, Sadia, Dhiloo, Azizullah Khan, Wajdi, Mehwish, Anjum, Fakhsheena, and Ansari, Saqib Hussain

Subjects
*ANTIBIOTICS, *ANTIMICROBIAL stewardship, *EVALUATION of human services programs, *SCIENTIFIC observation, *ACADEMIC medical centers, *BETA lactam antibiotics, *CO-trimoxazole, *HEMATOLOGY, *ACQUISITION of data, *AMINOGLYCOSIDES, *VANCOMYCIN, *TREATMENT effectiveness, *HUMAN services programs, *COMPARATIVE studies, *QUALITY assurance, *MEDICAL records, *DESCRIPTIVE statistics, *HEMATOLOGIC malignancies, *BACTERIAL diseases, *DRUG utilization, *PHYSICIANS, *DRUG resistance in microorganisms, *CANCER patient medical care, *LONGITUDINAL method
Abstract

Background: Infections are highly susceptible in patients with hematological malignancies due to immune suppression, immunosuppressive therapies and disease progression. Rational use of antibiotics following Antimicrobial Stewardship (AMS) guidelines in early detection and response to infection is significant to improve patient care. Objectives: The present study was conducted to determine the impact of clinical pharmacists' interventions (PIs) on antibiotics usage in hematology-oncology set up in Karachi, Pakistan. Methodology: An observational prospective study was conducted for a period of 4 months in a well-known 75-bed teaching hospital, specializing in bone marrow transplantation in Karachi, Pakistan without a structured Antimicrobial stewardship programs (ASPs). The information was gathered from patient medical histories, laboratory, and microbiological records. Results: A total of 876 PIs (1 to 5 per patient) were implemented. Dose modifications or interval changes accounted for the major interventions (n = 190, 21.6%). The majority of all recommendations were related to antipseudomonal β-lactams, aminoglycosides, sulfamethoxazole-trimethoprim and vancomycin. Overall, 94.3% (n = 876) of the 928 PIs were accepted. Conclusion: The PIs and the high physician acceptance rate may be useful for improving the safe use of antibiotics, lowering their toxicity, lowering the need for special-vigilance medications and potentially improving patient care. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

21. Assessment of risk factors associated with potential drug-drug interactions among patients suffering from chronic disorders

Author

Rasool, Muhammad Fawad, primary, Rehman, Anees ur, additional, Khan, Irfanullah, additional, Latif, Muhammad, additional, Ahmad, Imran, additional, Shakeel, Sadia, additional, Sadiq, Muhammad, additional, Hayat, Khezar, additional, Shah, Shahid, additional, Ashraf, Waseem, additional, Majeed, Abdul, additional, Hussain, Iltaf, additional, and Hussain, Rabia, additional

Published
2023
Full Text
View/download PDF

25. Healthcare Professionals’ Compliance with the Standard Management Guidelines towards the Use of Biological Disease-Modifying Anti-Rheumatic Drugs in Rheumatoid Arthritis Patients

Author

Shakeel, Sadia, primary, Iffat, Wajiha, additional, Qamar, Ambreen, additional, Rehman, Hina, additional, Ghuman, Faiza, additional, Butt, Fareeha, additional, ur Rehman, Anees, additional, Madléna, Melinda, additional, Paulik, Edit, additional, Gajdács, Márió, additional, and Jamshed, Shazia, additional

Published
2022
Full Text
View/download PDF

27. Knowledge, Attitude, and Practice Towards Biosimilars and Interchangeable Products: A Prescriptive Insight by the Pharmacists

Author

Shakeel, Sadia, Hassali, Mohamed Azmi, Rehman, Hina, Rehman, Anees ur, and Muneswarao, Jaya

Subjects
biosimilar medicines, pharmacists, healthcare, International Journal of General Medicine, Pakistan, interchangeable products, Original Research
Abstract

Sadia Shakeel,1,2 Mohamed Azmi Hassali,1 Hina Rehman,3 Anees ur Rehman,1,4 Jaya Muneswarao1 1Discipline of Social and Administrative Pharmacy, School of Pharmaceutical Sciences, University Sains Malaysia, Penang, Malaysia; 2Faculty of Pharmaceutical Sciences, Dow University of Health Sciences, Karachi, Pakistan; 3Institute of Pharmaceutical Sciences, Jinnah Sind Medical University, Karachi, Pakistan; 4Faculty of Pharmacy, Bahauddin Zakariya University, Multan, PakistanCorrespondence: Sadia Shakeel Email sadiashakeel@usm.myBackground: Pharmacists being the drug experts need to be well aware of the applied handling of biosimilar medicines (BSMs). They are an integral educator, trailblazer, and advocate of biosimilar integration across all clinical settings. Therefore, the current study was conducted to assess the pharmacists’ knowledge, attitude, and practices of integrating BSMs into clinical practice.Methods: The cross-sectional study was conducted from August 2019 to November 2019. The community pharmacies, clinical and academic settings in Karachi were approached for gathering the responses of pharmacists towards BSMs and interchangeable products using a 30-item survey form. Pearson correlation and independent sample t-test were used to identify the relationship among independent variables and the responses, considering p values < 0.05 as statistically significant.Results: Overall, there were 305 survey forms used with a response rate of 87.14%. More than 80% of the respondents have good knowledge about the definition, characteristics, safety and efficacy, compatibility, cost issues, and utilization of BSMs. Around half of the respondents (48.9%, [95% CI 46.6– 51.2]) were confident in using BSMs in clinical practice. However, they were concerned about the BSM’s safety profile (45.2%, [95% CI 42.1– 48.3]), quality (30.2%, [95% CI 28.3– 32.1]), and efficacy issues (32.3%, [95% CI 31.2– 37.5]).Conclusion: The findings revealed that pharmacists were well informed about the BSMs. However, some of the responses to the attitude demonstrated a lack of understanding of the application of that knowledge. The respondents persuaded that advanced patterns of diseases, product marketing stipulations, and need for better patient care drives higher demand for developing BSMs and were enthusiastic about gaining more insight to integrate BSMs into routine clinical practice.Keywords: pharmacists, biosimilar medicines, interchangeable products, healthcare, Pakistan

Published
2020

36. Xanthan Gum-Mediated Silver Nanoparticles for Ultrasensitive Electrochemical Detection of Hg 2+ Ions from Water.

Author

Shakeel, Sadia, Talpur, Farah Naz, Sirajuddin, Anwar, Nadia, Iqbal, Muhammad Aamir, Ibrahim, Adnan, Afridi, Hassan Imran, Unar, Ahsanullah, Khalid, Awais, Ahmed, Inas A., Lai, Wen-Cheng, and Bashir, Muhammad Sohail

Subjects
*SILVER nanoparticles, *CARBON electrodes, *MERCURY, *FOURIER transform infrared spectroscopy, *XANTHAN gum, *ATOMIC force microscopy, *TRACE elements in water, *IONS
Abstract

An environmentally safe, efficient, and economical microwave-assisted technique was selected for the production of silver nanoparticles (AgNPs). To prepare uniformly disseminated AgNPs, xanthan gum (XG) was utilized as both a reducing and capping agent. UV–Vis spectroscopy was used to characterize the formed XG-AgNPs, with the absorption band regulated at 414 nm under optimized parameters. Atomic force microscopy was used to reveal the size and shape of XG-AgNPs. The interactions between the XG capping agent and AgNPs observed using Fourier transform infrared spectroscopy. The XG-AgNPs were placed in between glassy carbon electrode and Nafion® surfaces and then deployed as sensors for voltammetric evaluation of mercury ions (Hg2+) using square-wave voltammetry as an analytical mode. Required Nafion® quantities, electrode behavior, electrolyte characteristics, pH, initial potentials, accumulation potentials, and accumulation durations were all comprehensively investigated. In addition, an electrochemical mechanism for the oxidation of Hg2+ was postulated. With an exceptional limit of detection of 0.18 ppb and an R2 value of 0.981, the sensors' measured linear response range was 0.0007–0.002 µM Hg2+. Hg2+ evaluations were ultimately unaffected by the presence of many coexisting metal ions (Cd2+, Pb2+, Cr2O4, Co2+,Cu2+, CuSO4). Spiked water samples were tested using the described approach, with Hg2+ recoveries ranging from 97% to 100%. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

41. Exploratory Findings of Prescribing Unlicensed and Off-Label Medicines Among Children and Neonates

Author

Shakeel,Sadia, Iffat,Wajiha, Nesar,Shagufta, Zaidi,Hina, and Jamshed,Shazia

Subjects
Integrated Pharmacy Research and Practice
Abstract

Sadia Shakeel,1,2 Wajiha Iffat,2 Shagufta Nesar,3 Hina Zaidi,3 Shazia Jamshed4,5 1Discipline of Social and Administrative Pharmacy, School of Pharmaceutical Sciences, University Sains Malaysia, Penang, Malaysia; 2Faculty of Pharmaceutical Sciences, Dow University of Health Sciences, Karachi, Pakistan; 3Faculty of Pharmacy, Hamdard University, Karachi, Pakistan; 4Department of Pharmacy Practice, Kulliyyah of Pharmacy, International Islamic University Malaysia, Kuantan, Pahang, Malaysia; 5Qualitative Research-Methodological Applications in Health Sciences Research Group, Kulliyyah of Pharmacy, International Islamic University Malaysia, Kuantan, Pahang, MalaysiaCorrespondence: Shazia JamshedPharmacy Practice, Kulliyyah of Pharmacy, Indera Mahkota Campus, Kuantan 25200, Pahang, MalaysiaEmail shazia_jamshed@iium.edu.myObjective: A cross-sectional study was carried out to evaluate the practice of unlicensed and off-label drug prescribing/dispensing in children and neonates by physicians and clinical pharmacists in the metropolitan city of Karachi.Methods: The study was conducted for the duration of 5 months – November 2018 to March 2019 – in different clinics and tertiary care hospitals of Karachi, Pakistan. Respondents were interviewed by our researchers using 30 items questionnaire. Descriptive statistics were used to evaluate the answers of respondents to survey items. Pearson correlation and independent sample t-test were employed to recognize the association between the responses of participants and independent variables. P values less than 0.05 were considered statistically significant.Results: A total of 421 questionnaires were completed by physicians and clinical pharmacists. The mean age of the study participants was 49.5 years. Around 98% of pharmacists and 93.5% of physicians were well conversant with the definition of unlicensed and off-label drugs. Around 68% of physicians and 77% of pharmacists reported that they were more concerned about the efficacy of such drugs as compared to that of licensed medicines in children. The most frequent off-label categories observed in the study were dose (65.21%) and indication (17.52%). A vast majority (> 80%) thought that approving new drugs by regulatory authorities will drop the occurrence of medication errors due to incorrect dosing. The British National Formulary (BNF) for children was used as the best reliable source of information among respondents.Conclusion: The present study highlighted the common practice of unlicensed and off-label drug prescribing in pediatrics; however, respondents showed their concern towards decreasing such practice and are likely to welcome initiatives intended to assure medication safety in children.Keywords: unlicensed drug and off-label prescribing, physicians, clinical pharmacists, Pakistan

Published
2020

45. Knowledge, Attitude, and Practice Towards Biosimilars and Interchangeable Products: A Prescriptive Insight by the Pharmacists

Author

Shakeel,Sadia, Hassali,Mohamed Azmi, Rehman,Hina, Rehman,Anees ur, Muneswarao,Jaya, Shakeel,Sadia, Hassali,Mohamed Azmi, Rehman,Hina, Rehman,Anees ur, and Muneswarao,Jaya

Abstract

Sadia Shakeel,1,2 Mohamed Azmi Hassali,1 Hina Rehman,3 Anees ur Rehman,1,4 Jaya Muneswarao1 1Discipline of Social and Administrative Pharmacy, School of Pharmaceutical Sciences, University Sains Malaysia, Penang, Malaysia; 2Faculty of Pharmaceutical Sciences, Dow University of Health Sciences, Karachi, Pakistan; 3Institute of Pharmaceutical Sciences, Jinnah Sind Medical University, Karachi, Pakistan; 4Faculty of Pharmacy, Bahauddin Zakariya University, Multan, PakistanCorrespondence: Sadia Shakeel Email sadiashakeel@usm.myBackground: Pharmacists being the drug experts need to be well aware of the applied handling of biosimilar medicines (BSMs). They are an integral educator, trailblazer, and advocate of biosimilar integration across all clinical settings. Therefore, the current study was conducted to assess the pharmacists’ knowledge, attitude, and practices of integrating BSMs into clinical practice.Methods: The cross-sectional study was conducted from August 2019 to November 2019. The community pharmacies, clinical and academic settings in Karachi were approached for gathering the responses of pharmacists towards BSMs and interchangeable products using a 30-item survey form. Pearson correlation and independent sample t-test were used to identify the relationship among independent variables and the responses, considering p values < 0.05 as statistically significant.Results: Overall, there were 305 survey forms used with a response rate of 87.14%. More than 80% of the respondents have good knowledge about the definition, characteristics, safety and efficacy, compatibility, cost issues, and utilization of BSMs. Around half of the respondents (48.9%, [95% CI 46.6– 51.2]) were confident in using BSMs in clinical practice. However, they were concerned about the BSM’s safety profile (45.2%, [95% CI 42.1– 48.3]), quality (30.2%, [95% CI 28.3– 32.1]), and efficacy issues (32.3%, [95% CI 31.2– 37.5]).Conclus

Published
2020

50. Quality and Potency Analysis of IVY Leaf Extract

Author

Yasmeen, Sidra, primary, Usman, Rafia, primary, Ayaz, Sultan, primary, Qamar, Fatima, primary, Zainab, Syeda, primary, Sadia, Halima, primary, Munir, Hira, primary, Arif, Amaris, primary, Shakeel, Sadia, primary, Zahoor, Aqib, primary, Khanum, Kashifa, primary, and Faridi, Zubair Uddin, primary

Published
2020
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results