Search

Objectives Sedation and stability during electroencephalography (EEG) in pediatrics have high clinical importance. This study compares the sedative properties of oral chloral hydrate (OCH) and intranasal fentanyl (INF). Materials & Methods This study was a randomized clinical trial conducted in 2020 in Isfahan City on sixty-two pediatric candidates for EEG. Patients were randomized into two groups receiving 50 mg/kg OCH and 2 µg/kg INF thirty minutes before the process. The heart rate (HR), mean arterial pressure (MAP), respiratory rate (RR), and oxygen saturation (O2 sat) of patients, sedation, and physician's satisfaction were measured and compared between groups. Results The HR of patients decreased significantly in both groups (P< 0.001), and the patients that received INF had significantly lower HR 15, 30, 45, and 60 minutes after drug administrations (P< 0.05). RR evaluation indicated significantly decreased RR in both groups (P< 0.001), and patients receiving INF had lower RR 30, 45, and 60 per minutes after drug administrations (P< 0.001). Both groups showed significantly increased sedation levels during the study (P< 0.001), and patients treated with INF had higher sedation levels 15, 30, and 45 minutes after drug administration. Satisfaction rates were higher among the group that received INF (P= 0.020). Conclusion The use of INF had significant analgesic and sedative effects on pediatrics undergoing EEG. [ABSTRACT FROM AUTHOR]

Introduction: According to studies, children are often kept fasting in intervals longer than the standard fasting time, which can lead to complications for them. So, there was little and contradictory evidence about fasting time and its complications, this study aimed to investigate the relationship between preoperative fasting time with vital signs and the type and dose of analgesic in pediatrics. Materials and Methods: In this cross-sectional research, 192 children aged between 6-36 months were surveyed in a specialized center for children. Children were examined through a researcher-made form in terms of preoperative fasting time, the type and dose of analgesic, as well as post-operative respiratory rate, pulse rate, and temperature through observation, pulse oximetry, and tympanic thermometer. Results: The mean fasting time was 8.09 hours. Fasting time was higher in children who took Apotel (P=0.03). The fasting time was significantly and directly related to the dose of Apotel and also to the total dose of the three drugs (P<0.001 and P<0.001, respectively). The mean body temperature of children who fasted for more than six hours was significantly lower than other children (P<0.001). Conclusion: The fasting time of children was more than standard times. Using a higher dose of Apotel and the total higher dose of three analgesic drugs suggests the existence of more pain in patients with longer fasting times. Moreover, increased fasting time led to a decrease in the temperature in pediatric patients. Therefore, it is necessary to reduce the fasting time of children to prevent the complications associated with it. [ABSTRACT FROM AUTHOR]