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1. Enhancing TinyML Security: Study of Adversarial Attack Transferability

Author

Shah, Parin, Govindarajulu, Yuvaraj, Kulkarni, Pavan, and Parmar, Manojkumar

Subjects
Computer Science - Cryptography and Security, Computer Science - Artificial Intelligence
Abstract

The recent strides in artificial intelligence (AI) and machine learning (ML) have propelled the rise of TinyML, a paradigm enabling AI computations at the edge without dependence on cloud connections. While TinyML offers real-time data analysis and swift responses critical for diverse applications, its devices' intrinsic resource limitations expose them to security risks. This research delves into the adversarial vulnerabilities of AI models on resource-constrained embedded hardware, with a focus on Model Extraction and Evasion Attacks. Our findings reveal that adversarial attacks from powerful host machines could be transferred to smaller, less secure devices like ESP32 and Raspberry Pi. This illustrates that adversarial attacks could be extended to tiny devices, underscoring vulnerabilities, and emphasizing the necessity for reinforced security measures in TinyML deployments. This exploration enhances the comprehension of security challenges in TinyML and offers insights for safeguarding sensitive data and ensuring device dependability in AI-powered edge computing settings., Comment: Accepted and presented at tinyML Foundation EMEA Innovation Forum 2024

Published
2024

3. Characterisation of older patients that require, but do not undergo, emergency laparotomy: a multicentre cohort study

Author

Shearer, Rosalyn, Mekhail, Peter, Ramsay, George, Nessa, Ashrafun, Iqbal, Rizwan, Maskell, Perry, Majeed, Mudassar, Dai, Nick, Bhojwani, Deepika, Anyomih, Theophilus, Lunevicius, Raimundas, Elkalbash, Rema, Shahzad, Khalid, Ahmed, Salma, Gahunia, Sukhpreet, Hopley, Philip, Nair, Dheepa, Reddington, Anne, Wilson, Jeremy, Lovett, Bryony, Iqbal, Muhammad Rafaih, Ramadan, Wafaa, Affify, Emma, Khan, Fatima, Tan, Silvian, Dawson, Joy, Eltarhoni, Khadiga, Young, Jamie, Lockwood, Sonia, Yiasemidou, Marina, Orchard, Melanie, Orchard, Phillipa, Randall, Jonathan, Barrow, Hannah, Dixon, Steve, Eardley, Nicola, Rajput, Kunal, Santoro, Giovanni, Mason, Sabrina, Bagnall, Nigel Mark, Kourdouli, Amar, Rajain, Sakshi, Curley, Daniel, Chandima Halahakoon, Vijitha, Thrikandiyur, Anu, Worsfold, James, Chouari, Tarak, Dent, Paul, Zhao, Sarah, Belgaumkar, Ajay, Maher, Sarah, Oyewole, Bankole, Weller, Sam, Davis, Mark, Fox, Katherine, Burton, Sarah, Iosif, Evangelia, Tobbal, Muhammed, Abdelkarim, Mostafa, Duvnjak, Haris, Morgan, Richard, Murali, Sreedutt, Murji, Bhaven, Venkatesan, Gowtham, Boardley, Rachael, Carson, Daniel, Galbraith, Norman, MacTier, Mhairi, Mailley, Keir, Meney, Laura, Persson, Pia, Stevenson, Richard, Haigh, Andrew, Kelly, Diane, Mellor, Samantha, Niaz, Muhammad Adnan, Peter, Mark, Smith, Douglas, Perin, Giordano, Hanbali, Nabih, Blackwell, James, Daliya, Prita, Herrod, Philip, Jibreel, Mohammed, Malcolm, Francesca, Photiou, Dana, Al-Khaddar, Ziad, Amir, Farhat, Bughio, Mumtaz, Gardiner, Felicity, Joyce, Nikki, Kennedy-Dalby, Andrew, Khan, Usman, McCoy, Sharon, Smart, Christopher J., Ward, Simon, Abdelsaid, Kirolos, AbdulAal, Yasser, Berski, Michael, Jayasankar, Balaji, Sandhu, Banher, Akhteruzzaman, Tahiyyah, Chan, Shirley, Dickson-Lowe, Richard, Kocsis, Anna Maria, Allen, Rhian, Bateman, Kellie, Shovelton, Charmaine, Smyth, Edward, Taylor, Daniel, Tennant, Anna, Chang, Jessica, Dowdeswell, Megan, Karri, Santosh, Neophytou, Chris, Yassin, Nuha, Bibi, Saira, Ulain, Noor, Evans, Luke, Cross, Katie, Fakhrul-aldeen, Mohammed, Jones, Stacey, Sarveswaran, Janahan, Aljarad, Feras, Collins, Amy, Eves, Joshua, Patel, Maleene, Sharieff, Imran, Smith, Emma, Treus, Estefania, McGuigan, Mari-Claire, Nicholoson, Gary, Pickering, Stacey, Husain, Najam, Narayanasamy, Sangara, Pradeep, Thomas, Rajebhosale, Ramprasad, Ravi, Prabhu, Elabbassy, Islam, Hao, Juen, Mak, Richard, Oliphant, Raymond, Powezka, Katarzyna, Asaad, Peter, Downs, Karen, Hylton, Jackie, Jalali, Uzma, Math, Suraj, Kourounis, Georgios, Mcilveen, Erin, Ng, Hwei Jene, Pope, Oscar, Argyropoulos, Susannah, Faulkner, Gemma, Spurring, Eleanor, Anis, Fady, Javanmard-Emamghissi, Hannah, Lee, Rachel, Redfern, Victoria, Saravanan, Nivetha, Tierney, Gill, Cullen, William, Kantola, Venla, Massey, Lisa, Orabi, Amira, Park, Linda, Rajaretnam, Niroshini, Smart, Neil, Ambler, Olivia, Damaskos, Dimitrios, Ewing, Anne, Mehta, Maithili, Skipworth, Richard, Alagaratnam, Swethan, Chowdhury, Shihad, Gupta, Aayush, Jones, Gareth, Mohamed, Guleed, Varcarda, Massimo, Abdel-dayem, Mahmoud, Mazumdar, Eshan, Miller, Bethany, Shah, Parin, Gupta, Sapna, Hawkings, Nancy, Herbert, Geraint, Indika, Kalhar, Mallison, Georgia, Smith, Laurie, Tolley, Thomas, Williams, Gethin, Burton, Keira, Cavallaro, Davide, Henry, Jayde, Parkin, Edward, Redfern, Jennifer, Sekhar, Hema, Murray, Hannah, Redman, Amelia, Thompson, Dolapo, Thornton, Sophie, Blake, Natalie, Mcleod, Ross, Pressler, Marc, Read, Howard, Shehata, Zak, Thomas, Michael, Walker, Cerys, Brown, Steven, Daniels, Sarah, Hawkins, Debby, Steele, Caroline, Berry, David, Dimitrova, Nora, Massella, Virginia, Mathew, Priya, Patel, Rikhilroy, Bakewell, Zoe, Collins, Alma, Fowler, George, Lawday, Samuel, McCarthy, Kathryn, Sheldon, James, Papakonstantinou, Dimitrios, Cox, Kofi, Kenington, Cleo, Mitchell, Robert, Thrumurthy, Sri, Clifford, Rachael, Kalaiselvan, Ramya, Leptidis, Ioannis, Connolly, Thomas, Evans, William, Kumar, Anil, Malik, Isfand, Nulty, Callula, Rai, Sajal, Brown, Ashley, Chew, Misha, Okpala, Amalachukwu, Tan, Yanyu, Magee, Cathy, Rossborough, Catherine, Manda, Vijay, McColl, Gillian, Norton, William, Ray, Christopher, Abdelrahman, Byrne, Clare, Caddick, Virginia, Ghanem, Ahmed, Marchese, Salvatore, Patel, Sabina, Singh, Kaushiki, Smith, Eleanor, Zarog, Mohamed, Caswell, Jack, Lukaszewicz, Alex, Manson, David, McKnight, Gerard, Duncan, Trish, Brown, Leo, Lam Chan, Deona Mei, Robertson, John, Al-Aqaileh, Ahmad, Chandratreya, Nitya, El-qudah, Jazal, Philip, Ken, Ben Hmida, Rami, Chohda, Ezzat, Gilbert, Kayleigh, Alqallaf, Addullah, Kamarizan, Mohamad, Ben Sassi, Abozed, Amin, Mohamed, Lim, Michael, Longbotham, David, Moussa, Ahmed, Sheridan, Kelda, Wilkins, Alex, Carter, Ben, Hewitt, Jonathan, Price, Angeline, McLennan, Elizabeth, Knight, Stephen R., Reeves, Nicola, Chandler, Susan, Boyle, Jemma, Pearce, Lyndsay, and Moug, Susan J.

Published
2024
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5. Effect of polyacid architecture and polycation molecular weight on lateral diffusion within multilayer films.

Author

Brito, Jordan, Shah, Parin Purvin, Aliakseyeu, Aliaksei, and Sukhishvili, Svetlana A.

Subjects
*MOLECULAR weights, *STAR-branched polymers, *METHACRYLIC acid, *DIFFUSION coefficients, *RADIATION exposure, *POLYELECTROLYTES, *MULTILAYERS
Abstract

Despite the potential use of polyelectrolyte multilayers for biomedical, separation, and energy applications, their dynamic properties are not sufficiently understood. In this work, center-of-mass diffusion of a weak polyacid—poly(methacrylic acid) (PMAA) of linear and 8-arm architecture (L-PMAA and 8-PMAA, respectively) and matched molecular weight—was studied in layer-by-layer (LbL) assemblies with poly(diallyldimethylammonium) chloride (PDADMAC) of varied molecular weight. The film deposition at low-salt, acidic conditions when PMAA was only partially ionized yielded thicker, more diffused layers with shorter PDADMAC chains, and bilayer thickness decreased for multilayers constructed with longer PDADMAC. The molecular architecture of PMAA had a weak effect on film growth, with bilayer thickness being ∼20% larger for L-PMAA for the films constructed with the shortest PDADMAC (35 kDa) and identical film growth for L-PMAA and 8-PMAA with the longest PDADMAC (300 kDa). The exposure of the multilayer films to 0.2M NaCl triggered a reduction in PMAA ionization and significant lateral diffusivity of fluorescently labeled PMAA molecules (PMAA*), with diffusion coefficients D ranging from 10−13 to 10−12 cm2/s, as determined by the fluorescence recovery after photobleaching technique. For all the films, polymer mobility was higher for star polyacids as compared to their linear counterparts, and the dependence of PMAA diffusion coefficient D on PDADMAC molecular weight (D ∼ M−n) was relatively weak (n < 0.6). However, 8-PMAA demonstrated an approximately doubled power exponent compared to the L-PMAA chains, suggesting a stronger effect of the molecular connectivity of the partner polycation molecules on the diffusion of star polyelectrolytes. [ABSTRACT FROM AUTHOR]

Published
2024
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6. The CD58-CD2 axis is co-regulated with PD-L1 via CMTM6 and shapes anti-tumor immunity

Author

Ho, Patricia, Melms, Johannes C., Rogava, Meri, Frangieh, Chris J., Poźniak, Joanna, Shah, Shivem B., Walsh, Zachary, Kyrysyuk, Oleksandr, Amin, Amit Dipak, Caprio, Lindsay, Fullerton, Benjamin T., Soni, Rajesh Kumar, Ager, Casey R., Biermann, Jana, Wang, Yiping, Khosravi-Maharlooei, Mohsen, Zanetti, Giorgia, Mu, Michael, Fatima, Hijab, Moore, Emily K., Vasan, Neil, Bakhoum, Samuel F., Reiner, Steven L., Bernatchez, Chantale, Sykes, Megan, Mace, Emily M., Wucherpfennig, Kai W., Schadendorf, Dirk, Bechter, Oliver, Shah, Parin, Schwartz, Gary K., Marine, Jean-Christophe, and Izar, Benjamin

Published
2023
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9. Exercise in heart failure

Author

Shah, Parin

Subjects
616.1, Medicine
Abstract

Introduction: In ambulatory patients with chronic stable heart failure, the cardinal symptom of exercise intolerance is not fully resolved despite optimal medical treatment. Identifying other treatments to improve exercise intolerance may improve quality of life. Methods: I investigated 2 treatments that may improve exercise intolerance in patients with heart failure. First, I conducted a review of oxygen supplementation in cardiovascular disease and then investigated the exercise capacity of 46 patients (mean age 75 years, 63% male and median N-terminal pro-B type natriuretic peptide 1432 (interquartile range: 543-2378 ng/l)) with heart failure and normal ejection fraction (HeFNEF), using different oxygen supplementation (21%, 28% and 40%). Second, I conducted a literature review on the acute effects of water immersion (WI) and swimming in patients with heart failure and reduced ejection fraction (HeFREF) and then investigated the haemodynamic and echocardiographic changes during warm WI in 17 patients with HeFREF (NYHA I and II; mean age 67 years, 88% male and mean left ventricular ejection fraction 33%) and 10 normal subjects. Results: In patients with HeFREF, high doses of oxygen have negative haemodynamics effects however low doses may improve exercise tolerance. In patients with HeFNEF, increasing oxygen supplementation during exertion leads to a small increase in exercise time. In patients with HeFREF, although exercise in water appears to be safe, the studies conducted have been small, very heterogeneous and inconclusive. In patients with HeFREF, warm WI causes an acute increase in cardiac output and a fall in systemic vascular resistance. Conclusion: Warm WI is well tolerated; however, whether swimming can be recommended as alternative to other forms of exercise or rehabilitation in patients with HeFREF needs further studies. In patients with HeFNEF, a disproportionate increase in left atrial pressure on exercise contributes to symptoms. However extra-cardiac mechanisms may also contribute to impaired exercise tolerance. Studies should also focus on treatment of co morbidities.

Published
2018

11. Crop Yield Prediction for India Using Regression Algorithms

Author

Timbadia, Devansh Hiren, Sudhanvan, Sughosh, Shah, Parin Jigishu, Agrawal, Supriya, Filipe, Joaquim, Editorial Board Member, Ghosh, Ashish, Editorial Board Member, Prates, Raquel Oliveira, Editorial Board Member, Zhou, Lizhu, Editorial Board Member, Singh, Mayank, editor, Tyagi, Vipin, editor, Gupta, P. K., editor, Flusser, Jan, editor, Ören, Tuncer, editor, and Sonawane, V. R., editor

Published
2021
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12. Advanced Rainfall Prediction Model for India Using Various Regression Algorithms

Author

Shah, Parin Jigishu, Timbadia, Devansh Hiren, Sudhanvan, Sughosh, Agrawal, Supriya, Kacprzyk, Janusz, Series Editor, Pal, Nikhil R., Advisory Editor, Bello Perez, Rafael, Advisory Editor, Corchado, Emilio S., Advisory Editor, Hagras, Hani, Advisory Editor, Kóczy, László T., Advisory Editor, Kreinovich, Vladik, Advisory Editor, Lin, Chin-Teng, Advisory Editor, Lu, Jie, Advisory Editor, Melin, Patricia, Advisory Editor, Nedjah, Nadia, Advisory Editor, Nguyen, Ngoc Thanh, Advisory Editor, Wang, Jun, Advisory Editor, Tiwari, Aruna, editor, Ahuja, Kapil, editor, Yadav, Anupam, editor, Bansal, Jagdish Chand, editor, Deep, Kusum, editor, and Nagar, Atulya K., editor

Published
2021
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16. Mapping variant effects on anti-tumor hallmarks of primary human T cells with base-editing screens

Author

Walsh, Zachary H., primary, Shah, Parin, additional, Kothapalli, Neeharika, additional, Shah, Shivem B., additional, Nikolenyi, Gergo, additional, Brodtman, D. Zack, additional, Leuzzi, Giuseppe, additional, Rogava, Meri, additional, Mu, Michael, additional, Ho, Patricia, additional, Abuzaid, Sinan, additional, Vasan, Neil, additional, AlQuraishi, Mohammed, additional, Milner, Joshua D., additional, Ciccia, Alberto, additional, Melms, Johannes C., additional, and Izar, Benjamin, additional

Published
2024
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17. Transcriptional mediators of treatment resistance in lethal prostate cancer

Author

He, Meng Xiao, Cuoco, Michael S., Crowdis, Jett, Bosma-Moody, Alice, Zhang, Zhenwei, Bi, Kevin, Kanodia, Abhay, Su, Mei-Ju, Ku, Sheng-Yu, Garcia, Maria Mica, Sweet, Amalia R., Rodman, Christopher, DelloStritto, Laura, Silver, Rebecca, Steinharter, John, Shah, Parin, and Izar, Benjamin

Subjects
Oncology, Experimental, Prostate cancer -- Drug therapy -- Genetic aspects, Metastasis -- Drug therapy -- Genetic aspects, Drug resistance -- Research, Genetic transcription -- Research, Cancer -- Research, Biological sciences, Health
Abstract

Metastatic castration-resistant prostate cancer is typically lethal, exhibiting intrinsic or acquired resistance to second-generation androgen-targeting therapies and minimal response to immune checkpoint inhibitors.sup.1. Cellular programs driving resistance in both cancer and immune cells remain poorly understood. We present single-cell transcriptomes from 14 patients with advanced prostate cancer, spanning all common metastatic sites. Irrespective of treatment exposure, adenocarcinoma cells pervasively coexpressed multiple androgen receptor isoforms, including truncated isoforms hypothesized to mediate resistance to androgen-targeting therapies.sup.2,3. Resistance to enzalutamide was associated with cancer cell-intrinsic epithelial-mesenchymal transition and transforming growth factor-[beta] signaling. Small cell carcinoma cells exhibited divergent expression programs driven by transcriptional regulators promoting lineage plasticity and HOXB5, HOXB6 and NR1D2 (refs. .sup.4-6). Additionally, a subset of patients had high expression of dysfunction markers on cytotoxic CD8.sup.+ T cells undergoing clonal expansion following enzalutamide treatment. Collectively, the transcriptional characterization of cancer and immune cells from human metastatic castration-resistant prostate cancer provides a basis for the development of therapeutic approaches complementing androgen signaling inhibition. Single-cell transcriptomic analysis of metastatic castration-resistant prostate cancer uncovers pervasive coexpression of androgen receptor isoforms and cancer cell-intrinsic and microenvironmental programs of treatment resistance, Author(s): Meng Xiao He [sup.1] [sup.2] [sup.3] , Michael S. Cuoco [sup.3] , Jett Crowdis [sup.2] [sup.3] , Alice Bosma-Moody [sup.2] [sup.3] [sup.4] , Zhenwei Zhang [sup.2] [sup.14] , Kevin [...]

Published
2021
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18. Massively parallel base editing screens to map variant effects on anti-tumor hallmarks of primary human T cells

Author

Walsh, Zachary H., primary, Shah, Parin, additional, Kothapalli, Neeharika, additional, Nikolenyi, Gergo, additional, Shah, Shivem B., additional, Leuzzi, Giuseppe, additional, Mu, Michael, additional, Ho, Patricia, additional, Abuzaid, Sinan, additional, Brodtman, Zack D., additional, Vasan, Neil, additional, AlQuraishi, Mohammed, additional, Milner, Joshua D., additional, Ciccia, Alberto, additional, Melms, Johannes C., additional, and Izar, Benjamin, additional

Published
2023
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20. A single-cell landscape of high-grade serous ovarian cancer

Author

Izar, Benjamin, Tirosh, Itay, Stover, Elizabeth H., Wakiro, Isaac, Cuoco, Michael S., Alter, Idan, Rodman, Christopher, Leeson, Rachel, Su, Mei-Ju, Shah, Parin, Iwanicki, Marcin, Walker, Sarah R., Kanodia, Abhay, Melms, Johannes C., Mei, Shaolin, Lin, Jia-Ren, Porter, Caroline B. M., Slyper, Michal, Waldman, Julia, Jerby-Arnon, Livnat, Ashenberg, Orr, Brinker, Titus J., Mills, Caitlin, Rogava, Meri, Vigneau, Sébastien, Sorger, Peter K., Garraway, Levi A., Konstantinopoulos, Panagiotis A., Liu, Joyce F., Matulonis, Ursula, Johnson, Bruce E., Rozenblatt-Rosen, Orit, Rotem, Asaf, and Regev, Aviv

Published
2020
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23. List of contributors

Author

Agrawal, Anurag, primary, Agrawal, Megha, additional, AlBanyan, Saleh, additional, Baranwal, Ajay Kumar, additional, Behr, Elijah R., additional, Bhatnagar, Deepak, additional, Bose, D., additional, Busi, María V., additional, Chakraborty, Samarpana, additional, Chitayat, David, additional, Craig, Donald P., additional, Das, Reena, additional, Davies, Dyfud Mark, additional, Doctor, Pezad, additional, Garofalidou, Tatiana, additional, Godbole, Koumudi, additional, Gogtay, N.J., additional, Gomez-Casati, Diego F., additional, Gupta, Anubhuti, additional, Haddad, Luciana Amaral, additional, Hamandi, Khalid, additional, Hegde, Shivaram, additional, Hodgson, Shirley V., additional, Kalhan, Atul, additional, Kirov, George, additional, Kleinendorst, Lotte, additional, Kumar, Dhavendra, additional, Lewis-Smith, David, additional, MacIver, Claire, additional, Mehra, Narinder Kumar, additional, Merchant, Rashid, additional, Morgan, Dafydd, additional, Munroe, Patricia B., additional, Ormerod, Julian O.M., additional, Pathan, Saad, additional, Peall, Kathryn J., additional, Ravi, R., additional, Rees, Elliott, additional, Schofield, Jonathan, additional, Shah, Parin, additional, Sharma, Gaurav, additional, Sharma, Prashant, additional, Sinajon, Pierre, additional, Singh, Indu, additional, Singh, Raghu Inder, additional, Soran, Handrean, additional, Stuart, Alan Graham, additional, Thatte, U.M., additional, Thomas, Naomi J.P., additional, Thomas, Rhys H., additional, Tully, IAN, additional, van Haelst, Mieke M., additional, Varaiya, Ami, additional, Yamada, Yoshiji, additional, and Zaidi, Abbas, additional

Published
2020
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28. Evaluating Lipid Profiles in Patients with Chronic Kidney Disease: A Biochemical Cross-Sectional Approach.

Author

Shah, Niel, Jyala, Abhilasha, Shah, Nitin, and Shah, Parin

Subjects
CHRONIC kidney failure, CHRONICALLY ill, LIPID metabolism, LIPIDS, HIGH density lipoproteins
Abstract

Background and Objective: Chronic Kidney Disease (CKD) affects millions worldwide, often leading to alterations in lipid metabolism. This study aims to evaluate the lipid profiles in CKD patients, providing insights into potential biochemical markers and therapeutic targets. Methods: In this cross-sectional study, lipid profiles of 200 patients diagnosed with various stages of CKD were analyzed. Blood samples were collected and tested for total cholesterol, low-density lipoprotein (LDL), high-density lipoprotein (HDL), and triglycerides. Demographic data and clinical parameters, including age, gender, body mass index, and CKD stage, were recorded. Statistical analysis was conducted to correlate lipid levels with CKD stages. Results: The study revealed significant alterations in lipid profiles correlated with the progression of CKD. Notably, there was an increase in total cholesterol and LDL levels, with a marked decrease in HDL levels in advanced stages of CKD. Triglyceride levels also showed a progressive increase. These changes were more pronounced in patients over 50 years of age and those with a higher BMI. Conclusion: The findings suggest that CKD significantly impacts lipid metabolism, with potential implications for cardiovascular risk in these patients. The study highlights the need for regular monitoring of lipid profiles in CKD patients and suggests potential avenues for targeted therapeutic interventions. Further research is recommended to explore the underlying mechanisms and to evaluate the impact of lipid-lowering therapies in this patient population. [ABSTRACT FROM AUTHOR]

Published
2023

31. Abstract 3517: Multi-modal single-cell and spatial genomics reveals genomic, adaptive and microenvironmental features of human non-small cell lung cancer brain metastasis

Author

Tagore, Somnath, primary, Caprio, Lindsay, additional, Amin, Amit Dipak, additional, Barrera, Irving, additional, Melms, Johannes, additional, Luthria, Karan, additional, Wang, Yiping, additional, Georgis, Yohanna, additional, Jaiswal, Abhi, additional, Lagos, Galina G., additional, Walsh, Zachary, additional, Shah, Parin, additional, Biermann, Jana, additional, Sheikh, Neha, additional, Ramaradj, Priyanka, additional, Anandasabapathy, Niroshana, additional, Hibshoosh, Hanina, additional, Schwartz, Gary, additional, Henick, Brian, additional, Taylor, Alison, additional, Chen, Fei, additional, and Izar, Benjamin, additional

Published
2023
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32. Data from Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids

Author

Jenkins, Russell W., primary, Aref, Amir R., primary, Lizotte, Patrick H., primary, Ivanova, Elena, primary, Stinson, Susanna, primary, Zhou, Chensheng W., primary, Bowden, Michaela, primary, Deng, Jiehui, primary, Liu, Hongye, primary, Miao, Diana, primary, He, Meng Xiao, primary, Walker, William, primary, Zhang, Gao, primary, Tian, Tian, primary, Cheng, Chaoran, primary, Wei, Zhi, primary, Palakurthi, Sangeetha, primary, Bittinger, Mark, primary, Vitzthum, Hans, primary, Kim, Jong Wook, primary, Merlino, Ashley, primary, Quinn, Max, primary, Venkataramani, Chandrasekar, primary, Kaplan, Joshua A., primary, Portell, Andrew, primary, Gokhale, Prafulla C., primary, Phillips, Bart, primary, Smart, Alicia, primary, Rotem, Asaf, primary, Jones, Robert E., primary, Keogh, Lauren, primary, Anguiano, Maria, primary, Stapleton, Lance, primary, Jia, Zhiheng, primary, Barzily-Rokni, Michal, primary, Cañadas, Israel, primary, Thai, Tran C., primary, Hammond, Marc R., primary, Vlahos, Raven, primary, Wang, Eric S., primary, Zhang, Hua, primary, Li, Shuai, primary, Hanna, Glenn J., primary, Huang, Wei, primary, Hoang, Mai P., primary, Piris, Adriano, primary, Eliane, Jean-Pierre, primary, Stemmer-Rachamimov, Anat O., primary, Cameron, Lisa, primary, Su, Mei-Ju, primary, Shah, Parin, primary, Izar, Benjamin, primary, Thakuria, Manisha, primary, LeBoeuf, Nicole R., primary, Rabinowits, Guilherme, primary, Gunda, Viswanath, primary, Parangi, Sareh, primary, Cleary, James M., primary, Miller, Brian C., primary, Kitajima, Shunsuke, primary, Thummalapalli, Rohit, primary, Miao, Benchun, primary, Barbie, Thanh U., primary, Sivathanu, Vivek, primary, Wong, Joshua, primary, Richards, William G., primary, Bueno, Raphael, primary, Yoon, Charles H., primary, Miret, Juan, primary, Herlyn, Meenhard, primary, Garraway, Levi A., primary, Van Allen, Eliezer M., primary, Freeman, Gordon J., primary, Kirschmeier, Paul T., primary, Lorch, Jochen H., primary, Ott, Patrick A., primary, Hodi, F. Stephen, primary, Flaherty, Keith T., primary, Kamm, Roger D., primary, Boland, Genevieve M., primary, Wong, Kwok-Kin, primary, Dornan, David, primary, Paweletz, Cloud Peter, primary, and Barbie, David A., primary

Published
2023
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33. Supp. Movie 3 from Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids

Author

Jenkins, Russell W., primary, Aref, Amir R., primary, Lizotte, Patrick H., primary, Ivanova, Elena, primary, Stinson, Susanna, primary, Zhou, Chensheng W., primary, Bowden, Michaela, primary, Deng, Jiehui, primary, Liu, Hongye, primary, Miao, Diana, primary, He, Meng Xiao, primary, Walker, William, primary, Zhang, Gao, primary, Tian, Tian, primary, Cheng, Chaoran, primary, Wei, Zhi, primary, Palakurthi, Sangeetha, primary, Bittinger, Mark, primary, Vitzthum, Hans, primary, Kim, Jong Wook, primary, Merlino, Ashley, primary, Quinn, Max, primary, Venkataramani, Chandrasekar, primary, Kaplan, Joshua A., primary, Portell, Andrew, primary, Gokhale, Prafulla C., primary, Phillips, Bart, primary, Smart, Alicia, primary, Rotem, Asaf, primary, Jones, Robert E., primary, Keogh, Lauren, primary, Anguiano, Maria, primary, Stapleton, Lance, primary, Jia, Zhiheng, primary, Barzily-Rokni, Michal, primary, Cañadas, Israel, primary, Thai, Tran C., primary, Hammond, Marc R., primary, Vlahos, Raven, primary, Wang, Eric S., primary, Zhang, Hua, primary, Li, Shuai, primary, Hanna, Glenn J., primary, Huang, Wei, primary, Hoang, Mai P., primary, Piris, Adriano, primary, Eliane, Jean-Pierre, primary, Stemmer-Rachamimov, Anat O., primary, Cameron, Lisa, primary, Su, Mei-Ju, primary, Shah, Parin, primary, Izar, Benjamin, primary, Thakuria, Manisha, primary, LeBoeuf, Nicole R., primary, Rabinowits, Guilherme, primary, Gunda, Viswanath, primary, Parangi, Sareh, primary, Cleary, James M., primary, Miller, Brian C., primary, Kitajima, Shunsuke, primary, Thummalapalli, Rohit, primary, Miao, Benchun, primary, Barbie, Thanh U., primary, Sivathanu, Vivek, primary, Wong, Joshua, primary, Richards, William G., primary, Bueno, Raphael, primary, Yoon, Charles H., primary, Miret, Juan, primary, Herlyn, Meenhard, primary, Garraway, Levi A., primary, Van Allen, Eliezer M., primary, Freeman, Gordon J., primary, Kirschmeier, Paul T., primary, Lorch, Jochen H., primary, Ott, Patrick A., primary, Hodi, F. Stephen, primary, Flaherty, Keith T., primary, Kamm, Roger D., primary, Boland, Genevieve M., primary, Wong, Kwok-Kin, primary, Dornan, David, primary, Paweletz, Cloud Peter, primary, and Barbie, David A., primary

Published
2023
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34. Supp. Movie 1 from Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids

Author

Jenkins, Russell W., primary, Aref, Amir R., primary, Lizotte, Patrick H., primary, Ivanova, Elena, primary, Stinson, Susanna, primary, Zhou, Chensheng W., primary, Bowden, Michaela, primary, Deng, Jiehui, primary, Liu, Hongye, primary, Miao, Diana, primary, He, Meng Xiao, primary, Walker, William, primary, Zhang, Gao, primary, Tian, Tian, primary, Cheng, Chaoran, primary, Wei, Zhi, primary, Palakurthi, Sangeetha, primary, Bittinger, Mark, primary, Vitzthum, Hans, primary, Kim, Jong Wook, primary, Merlino, Ashley, primary, Quinn, Max, primary, Venkataramani, Chandrasekar, primary, Kaplan, Joshua A., primary, Portell, Andrew, primary, Gokhale, Prafulla C., primary, Phillips, Bart, primary, Smart, Alicia, primary, Rotem, Asaf, primary, Jones, Robert E., primary, Keogh, Lauren, primary, Anguiano, Maria, primary, Stapleton, Lance, primary, Jia, Zhiheng, primary, Barzily-Rokni, Michal, primary, Cañadas, Israel, primary, Thai, Tran C., primary, Hammond, Marc R., primary, Vlahos, Raven, primary, Wang, Eric S., primary, Zhang, Hua, primary, Li, Shuai, primary, Hanna, Glenn J., primary, Huang, Wei, primary, Hoang, Mai P., primary, Piris, Adriano, primary, Eliane, Jean-Pierre, primary, Stemmer-Rachamimov, Anat O., primary, Cameron, Lisa, primary, Su, Mei-Ju, primary, Shah, Parin, primary, Izar, Benjamin, primary, Thakuria, Manisha, primary, LeBoeuf, Nicole R., primary, Rabinowits, Guilherme, primary, Gunda, Viswanath, primary, Parangi, Sareh, primary, Cleary, James M., primary, Miller, Brian C., primary, Kitajima, Shunsuke, primary, Thummalapalli, Rohit, primary, Miao, Benchun, primary, Barbie, Thanh U., primary, Sivathanu, Vivek, primary, Wong, Joshua, primary, Richards, William G., primary, Bueno, Raphael, primary, Yoon, Charles H., primary, Miret, Juan, primary, Herlyn, Meenhard, primary, Garraway, Levi A., primary, Van Allen, Eliezer M., primary, Freeman, Gordon J., primary, Kirschmeier, Paul T., primary, Lorch, Jochen H., primary, Ott, Patrick A., primary, Hodi, F. Stephen, primary, Flaherty, Keith T., primary, Kamm, Roger D., primary, Boland, Genevieve M., primary, Wong, Kwok-Kin, primary, Dornan, David, primary, Paweletz, Cloud Peter, primary, and Barbie, David A., primary

Published
2023
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35. Table S3 from Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids

Author

Jenkins, Russell W., primary, Aref, Amir R., primary, Lizotte, Patrick H., primary, Ivanova, Elena, primary, Stinson, Susanna, primary, Zhou, Chensheng W., primary, Bowden, Michaela, primary, Deng, Jiehui, primary, Liu, Hongye, primary, Miao, Diana, primary, He, Meng Xiao, primary, Walker, William, primary, Zhang, Gao, primary, Tian, Tian, primary, Cheng, Chaoran, primary, Wei, Zhi, primary, Palakurthi, Sangeetha, primary, Bittinger, Mark, primary, Vitzthum, Hans, primary, Kim, Jong Wook, primary, Merlino, Ashley, primary, Quinn, Max, primary, Venkataramani, Chandrasekar, primary, Kaplan, Joshua A., primary, Portell, Andrew, primary, Gokhale, Prafulla C., primary, Phillips, Bart, primary, Smart, Alicia, primary, Rotem, Asaf, primary, Jones, Robert E., primary, Keogh, Lauren, primary, Anguiano, Maria, primary, Stapleton, Lance, primary, Jia, Zhiheng, primary, Barzily-Rokni, Michal, primary, Cañadas, Israel, primary, Thai, Tran C., primary, Hammond, Marc R., primary, Vlahos, Raven, primary, Wang, Eric S., primary, Zhang, Hua, primary, Li, Shuai, primary, Hanna, Glenn J., primary, Huang, Wei, primary, Hoang, Mai P., primary, Piris, Adriano, primary, Eliane, Jean-Pierre, primary, Stemmer-Rachamimov, Anat O., primary, Cameron, Lisa, primary, Su, Mei-Ju, primary, Shah, Parin, primary, Izar, Benjamin, primary, Thakuria, Manisha, primary, LeBoeuf, Nicole R., primary, Rabinowits, Guilherme, primary, Gunda, Viswanath, primary, Parangi, Sareh, primary, Cleary, James M., primary, Miller, Brian C., primary, Kitajima, Shunsuke, primary, Thummalapalli, Rohit, primary, Miao, Benchun, primary, Barbie, Thanh U., primary, Sivathanu, Vivek, primary, Wong, Joshua, primary, Richards, William G., primary, Bueno, Raphael, primary, Yoon, Charles H., primary, Miret, Juan, primary, Herlyn, Meenhard, primary, Garraway, Levi A., primary, Van Allen, Eliezer M., primary, Freeman, Gordon J., primary, Kirschmeier, Paul T., primary, Lorch, Jochen H., primary, Ott, Patrick A., primary, Hodi, F. Stephen, primary, Flaherty, Keith T., primary, Kamm, Roger D., primary, Boland, Genevieve M., primary, Wong, Kwok-Kin, primary, Dornan, David, primary, Paweletz, Cloud Peter, primary, and Barbie, David A., primary

Published
2023
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36. Supplementary Data from Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids

Author

Jenkins, Russell W., primary, Aref, Amir R., primary, Lizotte, Patrick H., primary, Ivanova, Elena, primary, Stinson, Susanna, primary, Zhou, Chensheng W., primary, Bowden, Michaela, primary, Deng, Jiehui, primary, Liu, Hongye, primary, Miao, Diana, primary, He, Meng Xiao, primary, Walker, William, primary, Zhang, Gao, primary, Tian, Tian, primary, Cheng, Chaoran, primary, Wei, Zhi, primary, Palakurthi, Sangeetha, primary, Bittinger, Mark, primary, Vitzthum, Hans, primary, Kim, Jong Wook, primary, Merlino, Ashley, primary, Quinn, Max, primary, Venkataramani, Chandrasekar, primary, Kaplan, Joshua A., primary, Portell, Andrew, primary, Gokhale, Prafulla C., primary, Phillips, Bart, primary, Smart, Alicia, primary, Rotem, Asaf, primary, Jones, Robert E., primary, Keogh, Lauren, primary, Anguiano, Maria, primary, Stapleton, Lance, primary, Jia, Zhiheng, primary, Barzily-Rokni, Michal, primary, Cañadas, Israel, primary, Thai, Tran C., primary, Hammond, Marc R., primary, Vlahos, Raven, primary, Wang, Eric S., primary, Zhang, Hua, primary, Li, Shuai, primary, Hanna, Glenn J., primary, Huang, Wei, primary, Hoang, Mai P., primary, Piris, Adriano, primary, Eliane, Jean-Pierre, primary, Stemmer-Rachamimov, Anat O., primary, Cameron, Lisa, primary, Su, Mei-Ju, primary, Shah, Parin, primary, Izar, Benjamin, primary, Thakuria, Manisha, primary, LeBoeuf, Nicole R., primary, Rabinowits, Guilherme, primary, Gunda, Viswanath, primary, Parangi, Sareh, primary, Cleary, James M., primary, Miller, Brian C., primary, Kitajima, Shunsuke, primary, Thummalapalli, Rohit, primary, Miao, Benchun, primary, Barbie, Thanh U., primary, Sivathanu, Vivek, primary, Wong, Joshua, primary, Richards, William G., primary, Bueno, Raphael, primary, Yoon, Charles H., primary, Miret, Juan, primary, Herlyn, Meenhard, primary, Garraway, Levi A., primary, Van Allen, Eliezer M., primary, Freeman, Gordon J., primary, Kirschmeier, Paul T., primary, Lorch, Jochen H., primary, Ott, Patrick A., primary, Hodi, F. Stephen, primary, Flaherty, Keith T., primary, Kamm, Roger D., primary, Boland, Genevieve M., primary, Wong, Kwok-Kin, primary, Dornan, David, primary, Paweletz, Cloud Peter, primary, and Barbie, David A., primary

Published
2023
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37. Supp. Movie 2 from Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids

Author

Jenkins, Russell W., primary, Aref, Amir R., primary, Lizotte, Patrick H., primary, Ivanova, Elena, primary, Stinson, Susanna, primary, Zhou, Chensheng W., primary, Bowden, Michaela, primary, Deng, Jiehui, primary, Liu, Hongye, primary, Miao, Diana, primary, He, Meng Xiao, primary, Walker, William, primary, Zhang, Gao, primary, Tian, Tian, primary, Cheng, Chaoran, primary, Wei, Zhi, primary, Palakurthi, Sangeetha, primary, Bittinger, Mark, primary, Vitzthum, Hans, primary, Kim, Jong Wook, primary, Merlino, Ashley, primary, Quinn, Max, primary, Venkataramani, Chandrasekar, primary, Kaplan, Joshua A., primary, Portell, Andrew, primary, Gokhale, Prafulla C., primary, Phillips, Bart, primary, Smart, Alicia, primary, Rotem, Asaf, primary, Jones, Robert E., primary, Keogh, Lauren, primary, Anguiano, Maria, primary, Stapleton, Lance, primary, Jia, Zhiheng, primary, Barzily-Rokni, Michal, primary, Cañadas, Israel, primary, Thai, Tran C., primary, Hammond, Marc R., primary, Vlahos, Raven, primary, Wang, Eric S., primary, Zhang, Hua, primary, Li, Shuai, primary, Hanna, Glenn J., primary, Huang, Wei, primary, Hoang, Mai P., primary, Piris, Adriano, primary, Eliane, Jean-Pierre, primary, Stemmer-Rachamimov, Anat O., primary, Cameron, Lisa, primary, Su, Mei-Ju, primary, Shah, Parin, primary, Izar, Benjamin, primary, Thakuria, Manisha, primary, LeBoeuf, Nicole R., primary, Rabinowits, Guilherme, primary, Gunda, Viswanath, primary, Parangi, Sareh, primary, Cleary, James M., primary, Miller, Brian C., primary, Kitajima, Shunsuke, primary, Thummalapalli, Rohit, primary, Miao, Benchun, primary, Barbie, Thanh U., primary, Sivathanu, Vivek, primary, Wong, Joshua, primary, Richards, William G., primary, Bueno, Raphael, primary, Yoon, Charles H., primary, Miret, Juan, primary, Herlyn, Meenhard, primary, Garraway, Levi A., primary, Van Allen, Eliezer M., primary, Freeman, Gordon J., primary, Kirschmeier, Paul T., primary, Lorch, Jochen H., primary, Ott, Patrick A., primary, Hodi, F. Stephen, primary, Flaherty, Keith T., primary, Kamm, Roger D., primary, Boland, Genevieve M., primary, Wong, Kwok-Kin, primary, Dornan, David, primary, Paweletz, Cloud Peter, primary, and Barbie, David A., primary

Published
2023
Full Text
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41. Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq

Author

Tirosh, Itay, Izar, Benjamin, Prakadan, Sanjay M., Wadsworth, Marc H., Treacy, Daniel, Trombetta, John J., Rotem, Asaf, Rodman, Christopher, Lian, Christine, Murphy, George, Fallahi-Sichani, Mohammad, Dutton-Regester, Ken, Lin, Jia-Ren, Cohen, Ofir, Shah, Parin, Lu, Diana, Genshaft, Alex S., Hughes, Travis K., Ziegler, Carly G. K., Kazer, Samuel W., Gaillard, Aleth, Kolb, Kellie E., Villani, Alexandra-Chloé, Johannessen, Cory M., Andreev, Aleksandr Y., Van Allen, Eliezer M., Bertagnolli, Monica, Sorger, Peter K., Sullivan, Ryan J., Flaherty, Keith T., Frederick, Dennie T., Jané-Valbuena, Judit, Yoon, Charles H., Rozenblatt-Rosen, Orit, Shalek, Alex K., Regev, Aviv, and Garraway, Levi A.

Published
2016

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