1,038 results on '"Shah, Manish N"'
Search Results
2. Improving Older Adult Care Transitions, from the Emergency Department to Home: The Community Paramedic Transitions Intervention
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Gifford, Angela, Gussick, Megan, Shah, Manish N., Malone, Michael L., editor, Boltz, Marie, editor, Macias Tejada, Jonny, editor, and White, Heidi, editor
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- 2024
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3. Care Partner’s Experience with Care Received in the Emergency Department
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Hoonakker, Peter L. T., Carayon, Pascale, Werner, Nicole E., Dail, Paula V. W., Wust, Kathryn L., Rutkowski, Rachel, Barton, Hanna J., Patterson, Brian W., Shah, Manish N., Pulia, Michael S., Krause, Sheryl A., Buckley, Denise, Hankwitz, Jennifer, Schwei, Rebecca, Green, Rebecca K., Hoang, Ly, King, Barbara J., Tosi, Francesca, Editor-in-Chief, Germak, Claudio, Series Editor, Zurlo, Francesco, Series Editor, Jinyi, Zhi, Series Editor, Pozzatti Amadori, Marilaine, Series Editor, Caon, Maurizio, Series Editor, Melles, Marijke, editor, Albayrak, Armaĝan, editor, and Goossens, Richard H.M., editor
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- 2024
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4. Post-zygotic rescue of meiotic errors causes brain mosaicism and focal epilepsy
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Miller, Katherine E., Rivaldi, Adithe C., Shinagawa, Noriyuki, Sran, Sahib, Navarro, Jason B., Westfall, Jesse J., Miller, Anthony R., Roberts, Ryan D., Akkari, Yassmine, Supinger, Rachel, Hester, Mark E., Marhabaie, Mohammad, Gade, Meethila, Lu, Jinfeng, Rodziyevska, Olga, Bhattacharjee, Meenakshi B., Von Allmen, Gretchen K., Yang, Edward, Lidov, Hart G. W., Harini, Chellamani, Shah, Manish N., Leonard, Jeffrey, Pindrik, Jonathan, Shaikhouni, Ammar, Goldman, James E., Pierson, Christopher R., Thomas, Diana L., Boué, Daniel R., Ostendorf, Adam P., Mardis, Elaine R., Poduri, Annapurna, Koboldt, Daniel C., Heinzen, Erin L., and Bedrosian, Tracy A.
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- 2023
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5. Emergency Department Care Transitions for Patients With Cognitive Impairment: A Scoping Review
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Gettel, Cameron J, Falvey, Jason R, Gifford, Angela, Hoang, Ly, Christensen, Leslie A, Hwang, Ula, Shah, Manish N, Network, The GEAR 2 0-ADC, Aggarawal, Neelum, Allore, Heather, Amy, Aloysi, Belleville, Michael, Bellolio, M Fernanda, Betz, Marian, Biese, Kevin, Brandt, Cynthia, Bruursema, Stacey, Carnahan, Ryan, Carpenter, Christopher, Carr, David, Chin-Hansen, Jennie, Daven, Morgan, Degesys, Nida, Dresden, M Scott, Dussetschleger, Jeffrey, Ellenbogen, Michael, Falvey, Jason, Foster, Beverley, Gettel, Cameron, Gilmore-Bykovskyi, Andrea, Goldberg, Elizabeth, Han, Jin, Hardy, James, Hastings, S Nicole, Hirshon, Jon Mark, Hogan, Tess, Hung, William, Isaacs, Eric, Jaspal, Naveena, Jobe, Deb, Johnson, Jerry, Kelly, Kathleen, Kennedy, Maura, Kind, Amy, Leggett, Jesseca, Malone, Michael, Moccia, Michelle, Moreno, Monica, Morrow-Howell, Nancy, Nowroozpoor, Armin, Ohuabunwa, Ugochi, Oiyemhonian, Brenda, Perry, William, Prusaczk, Beth, Resendez, Jason, Rising, Kristen, Sano, Mary, Savage, Bob, Shah, Manish, Suyama, Joe, Swartzberg, Jeremy, Taylor, Zachary, Vaishal, Tolia, Vann, Allan, Webb, Teresa, and Weintraub, Sandra
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Emergency Care ,Brain Disorders ,Clinical Research ,Health Services ,Behavioral and Social Science ,Aging ,Management of diseases and conditions ,7.1 Individual care needs ,Mental health ,Good Health and Well Being ,Aged ,Cognitive Dysfunction ,Emergency Service ,Hospital ,Geriatric Assessment ,House Calls ,Humans ,Patient Transfer ,GEAR 2.0-ADC Network ,Care transitions ,cognitive impairment ,emergency department ,patient-centered outcomes ,Clinical Sciences ,Nursing ,Public Health and Health Services ,Geriatrics - Abstract
ObjectivesWe aimed to describe emergency department (ED) care transition interventions delivered to older adults with cognitive impairment, identify relevant patient-centered outcomes, and determine priority research areas for future investigation.DesignSystematic scoping review.Setting and participantsED patients with cognitive impairment and/or their care partners.MethodsInformed by the clinical questions, we conducted systematic electronic searches of medical research databases for relevant publications following published guidelines. The results were presented to a stakeholder group representing ED-based and non-ED-based clinicians, individuals living with cognitive impairment, care partners, and advocacy organizations. After discussion, they voted on potential research areas to prioritize for future investigations.ResultsFrom 3848 publications identified, 78 eligible studies underwent full text review, and 10 articles were abstracted. Common ED-to-community care transition interventions for older adults with cognitive impairment included interdisciplinary geriatric assessments, home visits from medical personnel, and telephone follow-ups. Intervention effects were mixed, with improvements observed in 30-day ED revisit rates but most largely ineffective at promoting connections to outpatient care or improving secondary outcomes such as physical function. Outcomes identified as important to adults with cognitive impairment and their care partners included care coordination between providers and inclusion of care partners in care management within the ED setting. The highest priority research area for future investigation identified by stakeholders was identifying strategies to tailor ED-to-community care transitions for adults living with cognitive impairment complicated by other vulnerabilities such as social isolation or economic disadvantage.Conclusions and implicationsThis scoping review identified key gaps in ED-to-community care transition interventions delivered to older adults with cognitive impairment. Combined with a stakeholder assessment and prioritization, it identified relevant patient-centered outcomes and clarifies priority areas for future investigation to improve ED care for individuals with impaired cognition, an area of critical need given the current population trends.
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- 2022
6. Risk Factors for Blunt Cerebrovascular Injury in a Cohort of Pediatric Patients With Cervical Seat Belt Sign
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Najar, Daniel A., Cardenas-Turanzas, Marylou, King, Jadeyn, Shah, Manish N., Cox, Charles S., and Ugalde, Irma T.
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- 2024
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7. Comparison of 2 Robotic Systems for Pediatric Stereoelectroencephalography Implantation
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Sickler, Robert W., Chandran, Arjun S., Funke, Michael E., Mosher, John C., Kommuru, Indira M., Lankford, Jeremy, Varnado, Shelley S., Von Allmen, Gretchen, Watkins, Michael W., Bonfante, Eliana E., Samant, Rohan, Kamali, Arash, Miller, Brandon A., and Shah, Manish N.
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- 2024
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8. Accuracy of the American College of Surgeons Minimum Criteria for Full Trauma Team Activation for Children
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Lerner, E. Brooke, Drendel, Amy L., Badawy, Mohamed, Cushman, Jeremy T., Fumo, Nicole, Jones, Courtney M.C., Shah, Manish N., and Gourlay, David M.
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- 2024
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9. A scoping review of work system elements that influence emergency department disposition decision-making
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Rutkowski, Rachel A., Scheer, Eleanore, Carlson, Claire, Parks, Reid, Pulia, Michael S., Patterson, Brian W., Shah, Manish N., Hoonakker, Peter L.T., Carayon, Pascale, Smith, Maureen, Christensen, Leslie A., and Werner, Nicole E.
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- 2023
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10. Risk factors for blunt cerebrovascular injury in the pediatric patient: A systematic review
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Schulz, Madison, Weihing, Veronica, Shah, Manish N., Cox, Charles S., Jr., and Ugalde, Irma
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- 2023
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11. Patient-centered care outcomes for patients in the emergency department with a non-English language preference: A scoping review
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Schwei, Rebecca J., Hoang, Ly, Wilson, Paije, Greene, Madelyne Z., Lor, Maichou, Shah, Manish N., and Pulia, Michael S.
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- 2023
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12. The Accuracy of Interqual Criteria in Determining the Observation versus Inpatient Status in Older Adults with Syncope
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Chang, Anna Marie, Hollander, Judd E, Su, Erica, Weiss, Robert E, Yagapen, Annick N, Malveau, Susan E, Adler, David H, Bastani, Aveh, Baugh, Christopher W, Caterino, Jeffrey M, Clark, Carol L, Diercks, Deborah B, Nicks, Bret A, Nishijima, Daniel K, Shah, Manish N, Stiffler, Kirk A, Storrow, Alan B, Wilber, Scott T, and Sun, Benjamin C
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Biomedical and Clinical Sciences ,Clinical Sciences ,Clinical Research ,Aging ,Aged ,Aged ,80 and over ,Cohort Studies ,Female ,Humans ,Inpatients ,Length of Stay ,Male ,Middle Aged ,Syncope ,case management ,geriatrics ,InterQual ,syncope ,Emergency & Critical Care Medicine ,Clinical sciences - Abstract
BackgroundMcKesson's InterQual criteria are widely used in hospitals to determine if patients should be classified as observation or inpatient status, but the accuracy of the criteria is unknown.ObjectiveWe sought to determine whether InterQual criteria accurately predicted length of stay (LOS) in older patients with syncope.MethodsWe conducted a secondary analysis of a cohort study of adults ≥60 years of age who had syncope. We calculated InterQual criteria and classified the patient as observation or inpatient status. Outcomes were whether LOS were less than or greater than 2 midnights.ResultsWe analyzed 2361 patients; 1227 (52.0%) patients were male and 1945 (82.8%) were white, with a mean age of 73.2 ± 9.0 years. The median LOS was 32.6 h (interquartile range 24.2-71.8). The sensitivity of InterQual criteria for LOS was 60.8% (95% confidence interval 57.9-63.6%) and the specificity was 47.8% (95% confidence interval 45.0-50.5%).ConclusionsIn older adults with syncope, those who met InterQual criteria for inpatient status had longer LOS compared with those who did not; however, the accuracy of the criteria to predict length of stay over 2 days is poor, with a sensitivity of 60% and a specificity of 48%. Future research should identify criteria to improve LOS prediction.
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- 2020
13. Risk Stratification of Older Adults Who Present to the Emergency Department With Syncope: The FAINT Score
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Probst, Marc A, Gibson, Thomas, Weiss, Robert E, Yagapen, Annick N, Malveau, Susan E, Adler, David H, Bastani, Aveh, Baugh, Christopher W, Caterino, Jeffrey M, Clark, Carol L, Diercks, Deborah B, Hollander, Judd E, Nicks, Bret A, Nishijima, Daniel K, Shah, Manish N, Stiffler, Kirk A, Storrow, Alan B, Wilber, Scott T, and Sun, Benjamin C
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Biomedical and Clinical Sciences ,Clinical Sciences ,Aging ,Cardiovascular ,Neurosciences ,Heart Disease ,Clinical Research ,Emergency Care ,Detection ,screening and diagnosis ,4.2 Evaluation of markers and technologies ,Good Health and Well Being ,Aged ,Area Under Curve ,Cardiovascular Diseases ,Emergency Service ,Hospital ,Female ,Health Status Indicators ,Humans ,Male ,Practice Guidelines as Topic ,Prospective Studies ,Risk Assessment ,Syncope ,United States ,Emergency & Critical Care Medicine ,Clinical sciences - Abstract
Study objectiveOlder adults with syncope are commonly treated in the emergency department (ED). We seek to derive a novel risk-stratification tool to predict 30-day serious cardiac outcomes.MethodsWe performed a prospective, observational study of older adults (≥60 years) with unexplained syncope or near syncope who presented to 11 EDs in the United States. Patients with a serious diagnosis identified in the ED were excluded. We collected clinical and laboratory data on all patients. Our primary outcome was 30-day all-cause mortality or serious cardiac outcome.ResultsWe enrolled 3,177 older adults with unexplained syncope or near syncope between April 2013 and September 2016. Mean age was 73 years (SD 9.0 years). The incidence of the primary outcome was 5.7% (95% confidence interval [CI] 4.9% to 6.5%). Using Bayesian logistic regression, we derived the FAINT score: history of heart failure, history of cardiac arrhythmia, initial abnormal ECG result, elevated pro B-type natriuretic peptide, and elevated high-sensitivity troponin T. A FAINT score of 0 versus greater than or equal to 1 had sensitivity of 96.7% (95% CI 92.9% to 98.8%) and specificity 22.2% (95% CI 20.7% to 23.8%), respectively. The FAINT score tended to be more accurate than unstructured physician judgment: area under the curve 0.704 (95% CI 0.669 to 0.739) versus 0.630 (95% CI 0.589 to 0.670).ConclusionAmong older adults with syncope or near syncope of potential cardiac cause, a FAINT score of zero had a reasonably high sensitivity for excluding death and serious cardiac outcomes at 30 days. If externally validated, this tool could improve resource use for this common condition.
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- 2020
14. Orthostatic vital signs do not predict 30 day serious outcomes in older emergency department patients with syncope: A multicenter observational study
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White, Jennifer L, Hollander, Judd E, Chang, Anna Marie, Nishijima, Daniel K, Lin, Amber L, Su, Erica, Weiss, Robert E, Yagapen, Annick N, Malveau, Susan E, Adler, David H, Bastani, Aveh, Baugh, Christopher W, Caterino, Jeffrey M, Clark, Carol L, Diercks, Deborah B, Nicks, Bret A, Shah, Manish N, Stiffler, Kirk A, Storrow, Alan B, Wilber, Scott T, and Sun, Benjamin C
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Biomedical and Clinical Sciences ,Cardiovascular Medicine and Haematology ,Clinical Sciences ,Clinical Research ,Cardiovascular ,Heart Disease ,Emergency Care ,Aged ,Aged ,80 and over ,Case-Control Studies ,Electrocardiography ,Emergency Service ,Hospital ,Female ,Heart Diseases ,Humans ,Male ,Middle Aged ,Physical Examination ,Prospective Studies ,Syncope ,Vital Signs ,Emergency & Critical Care Medicine ,Clinical sciences - Abstract
BackgroundSyncope is a common chief complaint among older adults in the Emergency Department (ED), and orthostatic vital signs are often a part of their evaluation. We assessed whether abnormal orthostatic vital signs in the ED are associated with composite 30-day serious outcomes in older adults presenting with syncope.MethodsWe performed a secondary analysis of a prospective, observational study at 11 EDs in adults ≥ 60 years who presented with syncope or near syncope. We excluded patients lost to follow up. We used the standard definition of abnormal orthostatic vital signs or subjective symptoms of lightheadedness upon standing to define orthostasis. We determined the rate of composite 30-day serious outcomes, including those during the index ED visit, such as cardiac arrhythmias, myocardial infarction, cardiac intervention, new diagnosis of structural heart disease, stroke, pulmonary embolism, aortic dissection, subarachnoid hemorrhage, cardiopulmonary resuscitation, hemorrhage/anemia requiring transfusion, with major traumatic injury from fall, recurrent syncope, and death) between the groups with normal and abnormal orthostatic vital signs.ResultsThe study cohort included 1974 patients, of whom 51.2% were male and 725 patients (37.7%) had abnormal orthostatic vital signs. Comparing those with abnormal to those with normal orthostatic vital signs, we did not find a difference in composite 30-serious outcomes (111/725 (15.3%) vs 184/1249 (14.7%); unadjusted odds ratio, 1.05 [95%CI, 0.81-1.35], p = 0.73). After adjustment for gender, coronary artery disease, congestive heart failure (CHF), history of arrhythmia, dyspnea, hypotension, any abnormal ECG, physician risk assessment, medication classes and disposition, there was no association with composite 30-serious outcomes (adjusted odds ratio, 0.82 [95%CI, 0.62-1.09], p = 0.18).ConclusionsIn a cohort of older adult patients presenting with syncope who were able to have orthostatic vital signs evaluated, abnormal orthostatic vital signs did not independently predict composite 30-day serious outcomes.
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- 2019
15. Clinical Benefit of Hospitalization for Older Adults With Unexplained Syncope: A Propensity-Matched Analysis
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Probst, Marc A, Su, Erica, Weiss, Robert E, Yagapen, Annick N, Malveau, Susan E, Adler, David H, Bastani, Aveh, Baugh, Christopher W, Caterino, Jeffrey M, Clark, Carol L, Diercks, Deborah B, Hollander, Judd E, Nicks, Bret A, Nishijima, Daniel K, Shah, Manish N, Stiffler, Kirk A, Storrow, Alan B, Wilber, Scott T, and Sun, Benjamin C
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Aging ,Clinical Research ,Aged ,Aged ,80 and over ,Emergency Service ,Hospital ,Female ,Hospitalization ,Humans ,Incidence ,Male ,Medically Unexplained Symptoms ,Middle Aged ,Patient Discharge ,Propensity Score ,Prospective Studies ,Risk Assessment ,Syncope ,United States ,Clinical Sciences ,Emergency & Critical Care Medicine - Abstract
Study objectiveMany adults with syncope are hospitalized solely for observation and testing. We seek to determine whether hospitalization versus outpatient management for older adults with unexplained syncope is associated with a reduction in postdisposition serious adverse events at 30 days.MethodsWe performed a propensity score analysis using data from a prospective, observational study of older adults with unexplained syncope or near syncope who presented to 11 emergency departments (EDs) in the United States. We enrolled adults (≥60 years) who presented with syncope or near syncope. We excluded patients with a serious diagnosis identified in the ED. Clinical and laboratory data were collected on all patients. The primary outcome was rate of post-ED serious adverse events at 30 days.ResultsWe enrolled 2,492 older adults with syncope and no serious ED diagnosis from April 2013 to September 2016. Mean age was 73 years (SD 8.9 years), and 51% were women. The incidence of serious adverse events within 30 days after the index visit was 7.4% for hospitalized patients and 3.19% for discharged patients, representing an unadjusted difference of 4.2% (95% confidence interval 2.38% to 6.02%). After propensity score matching on risk of hospitalization, there was no statistically significant difference in serious adverse events at 30 days between the hospitalized group (4.89%) and the discharged group (2.82%) (risk difference 2.07%; 95% confidence interval -0.24% to 4.38%).ConclusionIn our propensity-matched sample of older adults with unexplained syncope, for those with clinical characteristics similar to that of the discharged cohort, hospitalization was not associated with improvement in 30-day serious adverse event rates.
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- 2019
16. Recurrent syncope is not an independent risk predictor for future syncopal events or adverse outcomes
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Chang, Anna Marie, Hollander, Judd E, Su, Erica, Weiss, Robert E, Yagapen, Annick N, Malveau, Susan E, Adler, David H, Bastani, Aveh, Baugh, Christopher W, Caterino, Jeffrey M, Clark, Carol L, Diercks, Deborah B, Nicks, Bret A, Nishijima, Daniel K, Shah, Manish N, Stiffler, Kirk A, Storrow, Alan B, Wilber, Scott T, and Sun, Benjamin C
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Biomedical and Clinical Sciences ,Clinical Sciences ,Cardiovascular ,Clinical Research ,Aging ,Heart Disease ,Aged ,Aged ,80 and over ,Cardiovascular Diseases ,Case-Control Studies ,Emergency Service ,Hospital ,Female ,Humans ,Male ,Middle Aged ,Prospective Studies ,Recurrence ,Risk Assessment ,Risk Factors ,Syncope ,Emergency & Critical Care Medicine ,Clinical sciences - Abstract
Almost 20% of patients with syncope will experience another event. It is unknown whether recurrent syncope is a marker for a higher or lower risk etiology of syncope. The goal of this study is to determine whether older adults with recurrent syncope have a higher likelihood of 30-day serious clinical events than patients experiencing their first episode.MethodsThis study is a pre-specified secondary analysis of a multicenter prospective, observational study conducted at 11 emergency departments in the US. Adults 60 years or older who presented with syncope or near syncope were enrolled. The primary outcome was occurrence of 30-day serious outcome. The secondary outcome was 30-day serious cardiac arrhythmia. In multivariate analysis, we assessed whether prior syncope was an independent predictor of 30-day serious events.ResultsThe study cohort included 3580 patients: 1281 (35.8%) had prior syncope and 2299 (64.2%) were presenting with first episode of syncope. 498 (13.9%) patients had 1 prior episode while 771 (21.5%) had >1 prior episode. Those with recurrent syncope were more likely to have congestive heart failure, coronary artery disease, previous diagnosis of arrhythmia, and an abnormal ECG. Overall, 657 (18.4%) of the cohort had a serious outcome by 30 days after index ED visit. In multivariate analysis, we found no significant difference in risk of events (adjusted odds ratio 1.09; 95% confidence interval 0.90-1.31; p = 0.387).ConclusionIn older adults with syncope, a prior history of syncope within the year does not increase the risk for serious 30-day events.
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- 2019
17. Do High‐sensitivity Troponin and Natriuretic Peptide Predict Death or Serious Cardiac Outcomes After Syncope?
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Clark, Carol L, Gibson, Thomas A, Weiss, Robert E, Yagapen, Annick N, Malveau, Susan E, Adler, David H, Bastani, Aveh, Baugh, Christopher W, Caterino, Jeffrey M, Diercks, Deborah B, Hollander, Judd E, Nicks, Bret A, Nishijima, Daniel K, Shah, Manish N, Stiffler, Kirk A, Storrow, Alan B, Wilber, Scott T, and Sun, Benjamin C
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Cardiovascular ,Emergency Care ,Heart Disease ,Prevention ,Clinical Research ,Adult ,Aged ,Biomarkers ,Case-Control Studies ,Emergency Service ,Hospital ,Female ,Humans ,Male ,Middle Aged ,Natriuretic Peptide ,Brain ,Peptide Fragments ,Prospective Studies ,Syncope ,Troponin T ,Clinical Sciences ,Public Health and Health Services ,Emergency & Critical Care Medicine - Abstract
OBJECTIVES:An estimated 1.2 million annual emergency department (ED) visits for syncope/near syncope occur in the United States. Cardiac biomarkers are frequently obtained during the ED evaluation, but the prognostic value of index high-sensitivity troponin (hscTnT) and natriuretic peptide (NT-proBNP) are unclear. The objective of this study was to determine if hscTnT and NT-proBNP drawn in the ED are independently associated with 30-day death/serious cardiac outcomes in adult patients presenting with syncope. METHODS:A prespecified secondary analysis of a prospective, observational trial enrolling participants ≥ age 60 presenting with syncope, at 11 United States hospitals, was conducted between April 2013 and September 2016. Exclusions included seizure, stroke, transient ischemic attack, trauma, intoxication, hypoglycemia, persistent confusion, mechanical/electrical invention, prior enrollment, or predicted poor follow-up. Within 3 hours of consent, hscTnT and NT-proBNP were collected and later analyzed centrally using Roche Elecsys Gen 5 STAT and 2010 Cobas, respectively. Primary outcome was combined 30-day all-cause mortality and serious cardiac events. Adjusting for illness severity, using multivariate logistic regression analysis, variations between primary outcome and biomarkers were estimated, adjusting absolute risk associated with ranges of biomarkers using Bayesian Markov Chain Monte Carlo methods. RESULTS:The cohort included 3,392 patients; 367 (10.8%) experienced the primary outcome. Adjusted absolute risk for the primary outcome increased with hscTnT and NT-proBNP levels. HscTnT levels ≤ 5 ng/L were associated with a 4% (95% confidence interval [CI] = 3%-5%) outcome risk, and hscTnT > 50 ng/L, a 29% (95% CI = 26%-33%) risk. NT-proBNP levels ≤ 125 ng/L were associated with a 4% (95% CI = 4%-5%) risk, and NT-proBNP > 2,000 ng/L a 29% (95% CI = 25%-32%) risk. Likelihood ratios and predictive values demonstrated similar results. Sensitivity analyses excluding ED index serious outcomes demonstrated similar findings. CONCLUSIONS:hscTnT and NT-proBNP are independent predictors of 30-day death and serious outcomes in older ED patients presenting with syncope.
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- 2019
18. Comparison of 30-Day Serious Adverse Clinical Events for Elderly Patients Presenting to the Emergency Department With Near-Syncope Versus Syncope
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Bastani, Aveh, Su, Erica, Adler, David H, Baugh, Christopher, Caterino, Jeffrey M, Clark, Carol L, Diercks, Deborah B, Hollander, Judd E, Malveau, Susan E, Nicks, Bret A, Nishijima, Daniel K, Shah, Manish N, Stiffler, Kirk A, Storrow, Alan B, Wilber, Scott T, Yagapen, Annick N, Weiss, Robert E, and Sun, Benjamin C
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Cardiovascular ,Lung ,Aging ,Clinical Research ,Heart Disease ,Emergency Care ,Aged ,Aged ,80 and over ,Case-Control Studies ,Emergency Service ,Hospital ,Female ,Humans ,Male ,Middle Aged ,Prospective Studies ,Risk Assessment ,Syncope ,Clinical Sciences ,Emergency & Critical Care Medicine - Abstract
Study objectiveControversy remains in regard to the risk of adverse events for patients presenting with syncope compared with near-syncope. The purpose of our study is to describe the difference in outcomes between these groups in a large multicenter cohort of older emergency department (ED) patients.MethodsFrom April 28, 2013, to September 21, 2016, we conducted a prospective, observational study across 11 EDs in adults (≥60 years) with syncope or near-syncope. A standardized data extraction tool was used to collect information during their index visit and at 30-day follow-up. Our primary outcome was the incidence of 30-day death or serious clinical events. Data were analyzed with descriptive statistics and multivariate logistic regression analysis adjusting for relevant demographic or historical variables.ResultsA total of 3,581 patients (mean age 72.8 years; 51.6% men) were enrolled in the study. There were 1,380 patients (39%) presenting with near-syncope and 2,201 (61%) presenting with syncope. Baseline characteristics revealed a greater incidence of congestive heart failure, coronary artery disease, previous arrhythmia, nonwhite race, and presenting dyspnea in the near-syncope compared with syncope cohort. There were no differences in the primary outcome between the groups (near-syncope 18.7% versus syncope 18.2%). A multivariate logistic regression analysis identified no difference in 30-day serious outcomes for patients with near-syncope (odds ratio 0.94; 95% confidence interval 0.78 to 1.14) compared with syncope.ConclusionNear-syncope confers risk to patients similar to that of syncope for the composite outcome of 30-day death or serious clinical event.
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- 2019
19. Priorities to Overcome Barriers Impacting Data Science Application in Emergency Care Research.
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Puskarich, Michael A, Callaway, Clif, Silbergleit, Robert, Pines, Jesse M, Obermeyer, Ziad, Wright, David W, Hsia, Renee Y, Shah, Manish N, Monte, Andrew A, Limkakeng, Alexander T, Meisel, Zachary F, and Levy, Phillip D
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Humans ,Consensus ,Emergency Medicine ,Research ,Electronic Health Records ,Data Accuracy ,Data Science ,Emergency Care ,Clinical Research ,Networking and Information Technology R&D ,Generic health relevance ,Clinical Sciences ,Public Health and Health Services ,Emergency & Critical Care Medicine - Abstract
For a variety of reasons including cheap computing, widespread adoption of electronic medical records, digitalization of imaging and biosignals, and rapid development of novel technologies, the amount of health care data being collected, recorded, and stored is increasing at an exponential rate. Yet despite these advances, methods for the valid, efficient, and ethical utilization of these data remain underdeveloped. Emergency care research, in particular, poses several unique challenges in this rapidly evolving field. A group of content experts was recently convened to identify research priorities related to barriers to the application of data science to emergency care research. These recommendations included: 1) developing methods for cross-platform identification and linkage of patients; 2) creating central, deidentified, open-access databases; 3) improving methodologies for visualization and analysis of intensively sampled data; 4) developing methods to identify and standardize electronic medical record data quality; 5) improving and utilizing natural language processing; 6) developing and utilizing syndrome or complaint-based based taxonomies of disease; 7) developing practical and ethical framework to leverage electronic systems for controlled trials; 8) exploring technologies to help enable clinical trials in the emergency setting; and 9) training emergency care clinicians in data science and data scientists in emergency care medicine. The background, rationale, and conclusions of these recommendations are included in the present article.
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- 2019
20. Coaching older adults discharged home from the emergency department: The role of competence and emotion in following up with outpatient clinicians
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Mi, Ranran Z., Jacobsohn, Gwen C., Wu, Jiaxi, Shah, Manish N., Jones, Courtney M.C., Caprio, Thomas V., Cushman, Jeremy T., Lohmeier, Michael, Kind, Amy J.H., and Shah, Dhavan V.
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- 2022
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21. Performance of the American Heart Association/American College of Cardiology/Heart Rhythm Society versus European Society of Cardiology guideline criteria for hospital admission of patients with syncope
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Widmer, Velina, Leu, Kathrin, Reichlin, Tobias, Shrestha, Samyut, Freese, Michael, Krisai, Philipp, Belkin, Maria, Kawecki, Damian, Morawiec, Beata, Muzyk, Piotr, Nowalany-Kozielska, Ewa, Geigy, Nicolas, Martinez-Nadal, Gemma, Fuenzalida Inostroza, Carolina Isabel, Mandrión, José Bustamante, Poepping, Imke, Greenslade, Jaimi, Hawkins, Tracey, Rentsch, Katharina, Mitrovic, Sandra, von Eckardstein, Arnold, Buser, Andreas, Osswald, Stefan, Walter, Joan, Adler, David H., Bastani, Aveh, Baugh, Christopher W., Caterino, Jeffrey M., Diercks, Deborah B., Hollander, Judd E., Nicks, Bret A., Nishijima, Daniel K., Shah, Manish N., Stiffler, Kirk A., Wilber, Scott T., Storrow, Alan B., du Fay de Lavallaz, Jeanne, Zimmermann, Tobias, Badertscher, Patrick, Lopez-Ayala, Pedro, Nestelberger, Thomas, Miró, Òscar, Salgado, Emilio, Zaytseva, Xenia, Gafner, Michele Sara, Christ, Michael, Cullen, Louise, Than, Martin, Martin-Sanchez, F. Javier, Di Somma, Salvatore, Peacock, W. Frank, Keller, Dagmar I., Costabel, Juan Pablo, Sigal, Alan, Puelacher, Christian, Wussler, Desiree, Koechlin, Luca, Strebel, Ivo, Schuler, Sereina, Manka, Robert, Bilici, Murat, Lohrmann, Jens, Kühne, Michael, Breidthardt, Tobias, Clark, Carol L., Probst, Marc, Gibson, Thomas A., Weiss, Robert E., Sun, Benjamin C., and Mueller, Christian
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- 2022
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22. Scalar Assessment of the Family Caregiver Activation in Transitions Tool: An Exploratory Factor Analysis
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Gifford, Angela, Green, Rebecca K., Jacobsohn, Gwen C., Cochran, Amy L., Caprio, Thomas V., Cushman, Jeremy T., Jones, Courtney M.C., Kind, Amy J.H., Lohmeier, Michael, and Shah, Manish N.
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Aged -- Care and treatment ,Caregivers -- Services ,Health ,Seniors - Abstract
The Family Caregiver Activation in Transitions (FCAT) tool in its current, non-scalar form is not pragmatic for clinical use as each item is scored and intended to be interpreted individually. The purpose of the current study was to create a scalar version of the FCAT to facilitate better care communications between hospital staff and family caregivers. We also assessed the scale's validity by comparing the scalar version of the measure against patient health measures. Data were collected from 463 family caregiver–patient dyads from January 2016 to July 2019. An exploratory factor analysis was performed on the 10-item FCAT, resulting in a statistically homogeneous six-item scale focused on current caregiving activation factors. The measure was then compared against patient health measures, with no significant biases found. The six-item scalar FCAT can provide hospital staff insight into the level of caregiver activation occurring in the patient's health care and help tailor care transition needs for family caregiver–patient dyads. [Journal of Gerontological Nursing, 48(12), 35–42.], Family caregivers are characteristically defined as individuals who assist a care recipient in completing activities of daily living (ADLs), such as bathing, toileting, taking medications, and managing appointments (Coleman, Ground, [...]
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- 2022
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23. Satisfaction of Older Patients With Emergency Department Care: Psychometric Properties and Construct Validity of the Consumer Emergency Care Satisfaction Scale
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Hoonakker, Peter L. T., Carayon, Pascale, Brown, Roger L., Schwei, Rebecca, Green, Rebecca K., Rabas, Mackenzie, Hoang, Ly, Wust, Kathryn L., Rutkowski, Rachel, Salwei, Megan E., Barton, Hanna J., Shah, Manish N., Pulia, Michael S., Patterson, Brian W., Dail, Paula v.W., Krause, Sheryl, Buckley, Denise, Hankwitz, Jennifer, and Werner, Nicole E.
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- 2023
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24. Public Service in Neurosurgery
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Shah, Manish N., Sandberg, David I., Agarwal, Nitin, editor, and Reddy, Vamsi, editor
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- 2021
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25. Predictors of Clinically Significant Echocardiography Findings in Older Adults with Syncope: A Secondary Analysis
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Probst, Marc A, Gibson, Thomas A, Weiss, Robert E, Yagapen, Annick N, Malveau, Susan E, Adler, David H, Bastani, Aveh, Baugh, Christopher W, Caterino, Jeffrey M, Clark, Carol L, Diercks, Deborah B, Hollander, Judd E, Nicks, Bret A, Nishijima, Daniel K, Shah, Manish N, Stiffler, Kirk A, Storrow, Alan B, Wilber, Scott T, and Sun, Benjamin C
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Cardiovascular ,Clinical Research ,Aging ,Heart Disease ,Detection ,screening and diagnosis ,4.2 Evaluation of markers and technologies ,Aged ,Echocardiography ,Emergency Service ,Hospital ,Female ,Humans ,Male ,Middle Aged ,Predictive Value of Tests ,Prospective Studies ,Risk Assessment ,Sensitivity and Specificity ,Syncope ,Clinical Sciences ,General & Internal Medicine - Abstract
BackgroundSyncope is a common reason for visiting the emergency department (ED) and is associated with significant healthcare resource utilization.ObjectiveTo develop a risk-stratification tool for clinically significant findings on echocardiography among older adults presenting to the ED with syncope or nearsyncope.DesignProspective, observational cohort study from April 2013 to September 2016.SettingEleven EDs in the United States.PatientsWe enrolled adults (=60 years) who presented to the ED with syncope or near-syncope who underwent transthoracic echocardiography (TTE).MeasurementsThe primary outcome was a clinically significant finding on TTE. Clinical, electrocardiogram, and laboratory variables were also collected. Multivariable logistic regression analysis was used to identify predictors of significant findings on echocardiography.ResultsA total of 3,686 patients were enrolled. Of these, 995 (27%) received echocardiography, and 215 (22%) had a significant finding on echocardiography. Regression analysis identified five predictors of significant finding: (1) history of congestive heart failure, (2) history of coronary artery disease, (3) abnormal electrocardiogram, (4) high-sensitivity troponin-T >14 pg/mL, and 5) N-terminal pro B-type natriuretic peptide >125 pg/mL. These five variables make up the ROMEO (Risk Of Major Echocardiography findings in Older adults with syncope) criteria. The sensitivity of a ROMEO score of zero for excluding significant findings on echocardiography was 99.5% (95% CI: 97.4%-99.9%) with a specificity of 15.4% (95% CI: 13.0%-18.1%).ConclusionsIf validated, this risk-stratification tool could help clinicians determine which syncope patients are at very low risk of having clinically significant findings on echocardiography.RegistrationClinicalTrials.gov Identifier NCT01802398.
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- 2018
26. Outcomes of Patients With Syncope and Suspected Dementia
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Holden, Timothy R, Shah, Manish N, Gibson, Tommy A, Weiss, Robert E, Yagapen, Annick N, Malveau, Susan E, Adler, David H, Bastani, Aveh, Baugh, Christopher W, Caterino, Jeffrey M, Clark, Carol L, Diercks, Deborah B, Hollander, Judd E, Nicks, Bret A, Nishijima, Daniel K, Stiffler, Kirk A, Storrow, Alan B, Wilber, Scott T, and Sun, Benjamin C
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Clinical Research ,Patient Safety ,Emergency Care ,Aging ,Dementia ,Acquired Cognitive Impairment ,Brain Disorders ,Clinical Sciences ,Public Health and Health Services ,Emergency & Critical Care Medicine - Abstract
ObjectivesSyncope and near-syncope are common in patients with dementia and a leading cause of emergency department (ED) evaluation and subsequent hospitalization. The objective of this study was to describe the clinical trajectory and short-term outcomes of patients who presented to the ED with syncope or near-syncope and were assessed by their ED provider to have dementia.MethodsThis multisite prospective cohort study included patients 60 years of age or older who presented to the ED with syncope or near-syncope between 2013 and 2016. We analyzed a subcohort of 279 patients who were identified by the treating ED provider to have baseline dementia. We collected comprehensive patient-level, utilization, and outcomes data through interviews, provider surveys, and chart abstraction. Outcome measures included serious conditions related to syncope and death.ResultsOverall, 221 patients (79%) were hospitalized with a median length of stay of 2.1 days. A total of 46 patients (16%) were diagnosed with a serious condition in the ED. Of the 179 hospitalized patients who did not have a serious condition identified in the ED, 14 (7.8%) were subsequently diagnosed with a serious condition during the hospitalization, and an additional 12 patients (6.7%) were diagnosed postdischarge within 30 days of the index ED visit. There were seven deaths (2.5%) overall, none of which were cardiac-related. No patients who were discharged from the ED died or had a serious condition in the subsequent 30 days.ConclusionsPatients with perceived dementia who presented to the ED with syncope or near-syncope were frequently hospitalized. The diagnosis of a serious condition was uncommon if not identified during the initial ED assessment. Given the known iatrogenic risks of hospitalization for patients with dementia, future investigation of the impact of goals of care discussions on reducing potentially preventable, futile, or unwanted hospitalizations while improving goal-concordant care is warranted.
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- 2018
27. ECG Predictors of Cardiac Arrhythmias in Older Adults With Syncope
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Nishijima, Daniel K, Lin, Amber L, Weiss, Robert E, Yagapen, Annick N, Malveau, Susan E, Adler, David H, Bastani, Aveh, Baugh, Christopher W, Caterino, Jeffrey M, Clark, Carol L, Diercks, Deborah B, Hollander, Judd E, Nicks, Bret A, Shah, Manish N, Stiffler, Kirk A, Storrow, Alan B, Wilber, Scott T, and Sun, Benjamin C
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Biomedical and Clinical Sciences ,Clinical Sciences ,Cardiovascular ,Clinical Research ,Emergency Care ,Heart Disease ,Aged ,Aged ,80 and over ,Electrocardiography ,Emergency Service ,Hospital ,Female ,Follow-Up Studies ,Humans ,Incidence ,Male ,Middle Aged ,Prognosis ,Prospective Studies ,Risk Assessment ,Risk Factors ,Survival Rate ,Syncope ,United States ,Emergency & Critical Care Medicine ,Clinical sciences - Abstract
Study objectiveCardiac arrhythmia is a life-threatening condition in older adults who present to the emergency department (ED) with syncope. Previous work suggests the initial ED ECG can predict arrhythmia risk; however, specific ECG predictors have been variably specified. Our objective is to identify specific ECG abnormalities predictive of 30-day serious cardiac arrhythmias in older adults presenting to the ED with syncope.MethodsWe conducted a prospective, observational study at 11 EDs in adults aged 60 years or older who presented with syncope or near syncope. We excluded patients with a serious cardiac arrhythmia diagnosed during the ED evaluation from the primary analysis. The outcome was occurrence of 30-day serous cardiac arrhythmia. The exposure variables were predefined ECG abnormalities. Independent predictors were identified through multivariate logistic regression. The sensitivities and specificities of any predefined ECG abnormality and any ECG abnormality identified on adjusted analysis to predict 30-day serious cardiac arrhythmia were also calculated.ResultsAfter exclusion of 197 patients (5.5%; 95% confidence interval [CI] 4.7% to 6.2%) with serious cardiac arrhythmias in the ED, the study cohort included 3,416 patients. Of these, 104 patients (3.0%; 95% CI 2.5% to 3.7%) had a serious cardiac arrhythmia within 30 days from the index ED visit (median time to diagnosis 2 days [interquartile range 1 to 5 days]). The presence of nonsinus rhythm, multiple premature ventricular conductions, short PR interval, first-degree atrioventricular block, complete left bundle branch block, and Q wave/T wave/ST-segment abnormalities consistent with acute or chronic ischemia on the initial ED ECG increased the risk for a 30-day serious cardiac arrhythmia. This combination of ECG abnormalities had a similar sensitivity in predicting 30-day serious cardiac arrhythmia compared with any ECG abnormality (76.9% [95% CI 67.6% to 84.6%] versus 77.9% [95% CI 68.7% to 85.4%]) and was more specific (55.1% [95% CI 53.4% to 56.8%] versus 46.6% [95% CI 44.9% to 48.3%]).ConclusionIn older ED adults with syncope, approximately 3% receive a diagnosis of a serious cardiac arrhythmia not recognized on initial ED evaluation. The presence of specific abnormalities on the initial ED ECG increased the risk for 30-day serious cardiac arrhythmias.
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- 2018
28. Implementation of an Emergency Medicine Research Associates Program: Sharing 20 Years of Experience
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Abar, Beau, DeRienzo, Vincent, Glick, Joseph, Wood, Nancy, Shah, Manish N., Schneider, Sandra, and Adler, David
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Emergency Department ,research associates ,enrollment - Abstract
Introduction: The use of research associates (RA) programs to facilitate study enrollment in the emergency department was initiated during the mid-1990s. The University of Rochester Medical Center (URMC) was an early adopting site for this model, which has experienced considerable growth and development over the past 20 years. Methods: Our goal was to detail the Emergency Department Research Associates (EDRA) program processes developed at the URMC that has led to our program’s sustainability and productivity. These processes, and the lessons learned during their development, can assist institutions seeking to establish an RA program or refine an existing program. Results: Defined procedures for selecting, training, and monitoring EDRAs have been created and refined with the goal of maximizing study enrollment and minimizing protocol deviations. Our EDRA program functions as a paid service center for investigators, and our EDRAs engage in a variety of study-related activities including screening and enrolling patients, administering surveys, collecting bio-specimens, and making follow-up calls. Over the past two years, our program has averaged 222 enrollments/month (standard deviation = 79.93), gathering roughly 25 participants per study per month. Conclusion: Our EDRA model has consistently resulted in some of the highest number of enrollments across a variety of recently funded, multi-center studies. Maintaining a high-quality EDRA program requires continual investment on the part of the leadership team, though the benefits to investigators within and outside the department outweigh these costs.
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- 2018
29. Social Disconnection Among Older Adults Receiving Care in the Emergency Department
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Kandasamy, Deepika, Platts-Mills, Timothy F., Shah, Manish N., Van Orden, Kim A., and Betz, Marian E.
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Emergency department ,Older adults ,Social disconnection - Abstract
Introduction: Social disconnection is a public health problem in older adults, as it can lead to decreased quality of life for this population. This study describes the prevalence of social disconnection and patient interest in social resources to address social disconnection among older adults receiving emergency department (ED) care.Methods: We conducted a cross-sectional survey of community-dwelling older adults (≥65 years) receiving care at two U.S. EDs. We described participant characteristics (demographic, social, and health variables), social disconnection prevalence, and desire for social resources using percentages and 95% confidence intervals. Then, we performed Chi Square tests and logistic regression to determine factors associated with positive screens for social disconnection.Results: Of 289 participants, 51% were female and the median age was 72 (interquartile range: 69-78). Most (76%) engaged with the community regularly, and 68% reported driving. Regarding social disconnection, a substantial minority of participants reported feeling as if they were burdensome to others (37%); as if they didn’t belong (27%); or that people would be better off if they were gone (15%); 52% reported at least one of these. In separate regression analyses, the perceptions of being a burden or better off if gone were each significantly associated with needing help with routine tasks (odds ratio [OR] [5.87, 5.90]); perceived burden was associated with hospitalization in theprior month (OR [2.09]); and low belonging was associated with not engaging in the community regularly (OR [2.50]), not seeing family regularly (OR [3.82]), and difficulty affording food (OR [2.50]). Regarding potential ED referrals, most participants were interested in transportation options (68%), food assistance (58%), and mental health resources (55%). Participants experiencing difficulties affording food were interested in food and housing assistance (p=.03; p=.01).Conclusion: Over half of this sample of older ED patients reported feeling socially disconnected. Social and functional health problems are often related and both must be addressed to optimize older ED patient quality of life. Future research should consider the impact of social disconnection on older adults discharged from the ED and work to develop ED services that could refer this population to programs that may decrease social disconnection.
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- 2018
30. Risk Factors in Pediatric Blunt Cervical Vascular Injury and Significance of Seatbelt Sign
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Ugalde, Irma T., Claiborne, Mary K., Cardenas-Turanzas, Marylou, Shah, Manish N., Langabeer II, James R., and Patel, Rajan
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pediatric cerebrovascular accident ,computed tomography angiogram ,blunt cervical vascular injury - Abstract
Introduction: Computed tomography angiography (CTA) is used to screen patients for cerebrovascular injury after blunt trauma, but risk factors are not clearly defined in children. This modality has inherent radiation exposure. We set out to better delineate the risk factors associated with blunt cervical vascular injury (BCVI) in children with attention to the predictive value of seatbelt sign of the neck. Methods: We collected demographic, clinical and radiographic data from the electronic medical record and a trauma registry for patients less than age 18 years who underwent CTA of the neck in their evaluation at a Level I trauma center from November 2002 to December 2014 (12 years). The primary outcome was BCVI. Results: We identified 11,446 pediatric blunt trauma patients of whom 375 (2.7%) underwent CTA imaging. Fifty-three patients (0.4%) were diagnosed with cerebrovascular injuries. The average age of patients was 12.6 years and included 66% males. Nearly half of the population was white (52%). Of those patients who received CTA, 53 (14%) were diagnosed with arterial injury of various grades (I-V). We created models to evaluate factors independently associated with BCVI. The independent predictors associated with BCVI were Injury Severity Score >/= 16 (odds ratio [OR] [2.35]; 95% confidence interval [CI] [1.11-4.99%]), infarct on head imaging (OR [3.85]; 95% CI [1.49-9.93%]), hanging mechanism (OR [8.71]; 95% CI [1.52-49.89%]), cervical spine fracture (OR [3.84]; 95% CI [1.94-7.61%]) and basilar skull fracture (OR [2.21]; 95% CI [1.13-4.36%]). The same independent predictors remained associated with BCVI when excluding hanging mechanism from the multivariate regression analysis. Seatbelt sign of the neck was not associated with BCVI (p=0.68). Conclusion: We have found independent predictors of BCVI in pediatric patients. These may help in identifying children that may benefit from screening with CTA of the neck.
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- 2018
31. Comparing emergency department use among individuals with varying levels of cognitive impairment
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Green, Rebecca K., Shah, Manish N., Clark, Lindsay R., Batt, Robert J., Chin, Nathaniel A., and Patterson, Brian W.
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- 2022
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32. Academic Detailing as a Health Information Technology Implementation Method: Supporting the Design and Implementation of an Emergency Department–Based Clinical Decision Support Tool to Prevent Future Falls
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Barton, Hanna J, primary, Maru, Apoorva, additional, Leaf, Margaret A, additional, Hekman, Daniel J, additional, Wiegmann, Douglas A, additional, Shah, Manish N, additional, and Patterson, Brian W, additional
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- 2024
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33. Call me Dr Ishmael: trends in electronic health record notes available at emergency department visits and admissions
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Patterson, Brian W, primary, Hekman, Daniel J, additional, Liao, Frank J, additional, Hamedani, Azita G, additional, Shah, Manish N, additional, and Afshar, Majid, additional
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- 2024
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34. Disparate perspectives: Exploring healthcare professionals' misaligned mental models of older adults’ transitions of care between the emergency department and skilled nursing facility
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Werner, Nicole E., Rutkowski, Rachel A., Krause, Sheryl, Barton, Hanna J., Wust, Kathryn, Hoonakker, Peter, King, Barbara, Shah, Manish N., Pulia, Michael S., Brenny-Fitzpatrick, Maria, Smith, Maureen, and Carayon, Pascale
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- 2021
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35. Convolutional Neural Networks for Pediatric Refractory Epilepsy Classification Using Resting-State Functional Magnetic Resonance Imaging
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Nguyen, Ryan D., Kennady, Emmett H., Smyth, Matthew D., Zhu, Liang, Pao, Ludovic P., Swisher, Shannon K., Rosas, Alberto, Mitra, Anish, Patel, Rajan P., Lankford, Jeremy, Von Allmen, Gretchen, Watkins, Michael W., Funke, Michael E., and Shah, Manish N.
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- 2021
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36. Minimizing Attrition for Multisite Emergency Care Research
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Nicks, Bret A, Shah, Manish N, Adler, David H, Bastani, Aveh, Baugh, Christopher W, Caterino, Jeffrey M, Clark, Carol L, Diercks, Deborah B, Hollander, Judd E, Malveau, Susan E, Nishijima, Daniel K, Stiffler, Kirk A, Storrow, Alan B, Wilber, Scott T, Yagapen, Annick N, and Sun, Benjamin C
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Biomedical and Clinical Sciences ,Clinical Sciences ,Clinical Research ,Health Services ,Health and social care services research ,8.1 Organisation and delivery of services ,Aftercare ,Aged ,Data Collection ,Emergency Medical Services ,Health Services Research ,Humans ,Male ,Medical Records ,Middle Aged ,Multicenter Studies as Topic ,Patient Dropouts ,Patient Selection ,Prospective Studies ,Public Health and Health Services ,Emergency & Critical Care Medicine ,Clinical sciences - Abstract
Loss to follow-up of enrolled patients (a.k.a. attrition) is a major threat to study validity and power. Minimizing attrition can be challenging even under ideal research conditions, including the presence of adequate funding, experienced study personnel, and a refined research infrastructure. Emergency care research is shifting toward enrollment through multisite networks, but there have been limited descriptions of approaches to minimize attrition for these multicenter emergency care studies. This concept paper describes a stepwise approach to minimize attrition, using a case example of a multisite emergency department prospective cohort of over 3,000 patients that has achieved a 30-day direct phone follow-up attrition rate of
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- 2017
37. A Consensus-Driven Agenda for Emergency Medicine Firearm Injury Prevention Research
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Ranney, Megan L, Fletcher, Jonathan, Alter, Harrison, Barsotti, Christopher, Bebarta, Vikhyat S, Betz, Marian E, Carter, Patrick M, Cerdá, Magdalena, Cunningham, Rebecca M, Crane, Peter, Fahimi, Jahan, Miller, Matthew J, Rowhani-Rahbar, Ali, Vogel, Jody A, Wintemute, Garen J, Waseem, Muhammad, Shah, Manish N, Research, A Subcommittee of the ACEP Research Committee ACEP Technical Advisory Group on Firearm Injury, Barsotti, Christopher E, Betz, Marian, Borke, Jesse, Boudreaux, Edwin D, Brown, Kathleen, Frisby, Bianca, Crane, Peter W, Cunningham, Rebecca, Fleegler, Eric W, Geyer, Brian, Liang, Stephen Y, O'Connor, Robert E, Papachristos, Andrew, Rivara, Fred, Swanson, Jeffrey G, and Wintemute, Garen
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Biomedical and Clinical Sciences ,Clinical Sciences ,Prevention ,Emergency Care ,Violence Research ,Mental Health ,Clinical Research ,Physical Injury - Accidents and Adverse Effects ,Peace ,Justice and Strong Institutions ,Advisory Committees ,Consensus ,Emergency Medicine ,Firearms ,Health Services Research ,Humans ,Risk Factors ,Wounds ,Gunshot ,Suicide Prevention ,ACEP Technical Advisory Group on Firearm Injury Research ,a Subcommittee of the ACEP Research Committee ,Emergency & Critical Care Medicine ,Clinical sciences - Abstract
Study objectiveTo identify critical emergency medicine-focused firearm injury research questions and develop an evidence-based research agenda.MethodsNational content experts were recruited to a technical advisory group for the American College of Emergency Physicians Research Committee. Nominal group technique was used to identify research questions by consensus. The technical advisory group decided to focus on 5 widely accepted categorizations of firearm injury. Subgroups conducted literature reviews on each topic and developed preliminary lists of emergency medicine-relevant research questions. In-person meetings and conference calls were held to iteratively refine the extensive list of research questions, following nominal group technique guidelines. Feedback from external stakeholders was reviewed and integrated.ResultsFifty-nine final emergency medicine-relevant research questions were identified, including questions that cut across all firearm injury topics and questions specific to self-directed violence (suicide and attempted suicide), intimate partner violence, peer (nonpartner) violence, mass violence, and unintentional ("accidental") injury. Some questions could be addressed through research conducted in emergency departments; others would require work in other settings.ConclusionThe technical advisory group identified key emergency medicine-relevant firearm injury research questions. Emergency medicine-specific data are limited for most of these questions. Funders and researchers should consider increasing their attention to firearm injury prevention and control, particularly to the questions identified here and in other recently developed research agendas.
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- 2017
38. Patient Perspectives on Accessing Acute Illness Care
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Finta, Mary K., Borkenhagen, Amy, Werner, Nicole E., Duckles, Joyce, Sellers, Craig R., Seshadri, Sandhya, Lampo, Denise, and Shah, Manish N.
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access ,geriatrics ,emergency medicine - Abstract
Introduction: Older adults use the emergency department (ED) at high rates, including for illnesses that could be managed by their primary care providers (PCP). Policymakers have implemented barriers and incentives, often financial, to try to modify use patterns but with limited success. This study aims to understand the factors that influence older adults’ decision to obtain acute illness care from the ED rather than from their PCPs. Methods: We performed a qualitative study using a directed content analysis approach from February to October 2013. Fifteen community-dwelling older adults age≥65 years who presented to the ED of an academic medical center hospital for care and who were discharged home were enrolled. Semi-structured interviews were conducted initially in the ED and subsequently in patients’ homes over the following six weeks. All interviews were audio-recorded, transcribed, verified, and coded. The study team jointly analyzed the data and identified themes that emerged from the interviews. Results: The average age of study participants was 74 years (standard deviation ±7.2 years); 53% were female; 80% were white. We found five themes that influenced participants’ decisions to obtain acute illness care from the ED: limited availability of PCP-based care, variable interactions with healthcare providers and systems, limited availability of transportation for illness care, desire to avoid burdening friends and family, and previous experiences with illnesses. Conclusion: Community-dwelling older adults integrate multiple factors when deciding to obtain care from an ED rather than their PCPs. These factors relate to personal and social considerations, practical issues, and individual perceptions based on previous experiences. If these findings are validated in confirmatory studies, policymakers wishing to modify where older adults receive care should consider person-centered interventions at the system and individual level, such as decision support, telemedicine, improved transport services, enhancing PCPs’ capabilities, and enhancing EDs’ resources to care for older patients.
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- 2017
39. Association between social isolation and outpatient follow-up in older adults following emergency department discharge
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Cayenne, Nia A., Jacobsohn, Gwen Costa, Jones, Courtney M.C., DuGoff, Eva H., Cochran, Amy L., Caprio, Thomas V., Cushman, Jeremy T., Green, Rebecca K., Kind, Amy J.H., Lohmeier, Michael, Mi, Ranran, and Shah, Manish N.
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- 2021
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40. Paenibacillus dendritiformis Meningitis, Brain Abscesses and Cystic Encephalomalacia in an Infant: Case Presentation and Review of the Literature
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Tabarani, Christy, Heresi, Gloria P., Murphy, James R., Al Hammoud, Roukaya, Deyanov, Alex, Dinh, An Q., Arias, Cesar A., Baptista, Rodrigo, Wanger, Audrey, Shah, Manish N., Miller, Brandon, Masson, Manon F., Foster, Catherine E., and Hanson, Blake M.
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- 2022
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41. Elevation of Depressed Skull Fracture in Neonates Using a Breast Pump and a Custom-Molded Flange.
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Martinez, Emilie L., Welscher, Ashley, Shah, Manish N., and Sandberg, David I.
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- 2024
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42. Exploring SEIPS 2.0 as a model for analyzing care transitions across work systems
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Werner, Nicole E., Rutkowski, Rachel, Graske, Amy, Finta, Mary K., Sellers, Craig R., Seshadri, Sandhya, and Shah, Manish N.
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- 2020
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43. Back to the Beginning: An Algorithmic Approach to Neonatal Myelomeningocele Repair
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Fairchild, Berry, Cepeda, Alfredo, Jr, Maiorino, Eric, Shah, Manish N., Sandberg, David I., Fletcher, Stephen A., Nguyen, Phuong D., and Greives, Matthew R.
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- 2022
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44. Call Me Dr. Ishmael: Trends in Electronic Health Record Notes Available at ED Visits and Admissions
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Patterson, Brian W, primary, Hekman, Daniel J, additional, Liao, Frank, additional, Hamedani, Azita, additional, Shah, Manish N, additional, and Afshar, Majid, additional
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- 2024
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45. Reliability of Clinical Assessments in Older Adults With Syncope or Near Syncope
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Nishijima, Daniel K, Laurie, Amber L, Weiss, Robert E, Yagapen, Annick N, Malveau, Susan E, Adler, David H, Bastani, Aveh, Baugh, Christopher W, Caterino, Jeffrey M, Clark, Carol L, Diercks, Deborah B, Hollander, Judd E, Nicks, Bret A, Shah, Manish N, Stiffler, Kirk A, Storrow, Alan B, Wilber, Scott T, and Sun, Benjamin C
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Biomedical and Clinical Sciences ,Clinical Sciences ,Patient Safety ,Cardiovascular ,Health Services ,Clinical Research ,Aged ,Aged ,80 and over ,Cross-Sectional Studies ,Emergency Service ,Hospital ,Female ,Hospitalization ,Humans ,Male ,Medical History Taking ,Middle Aged ,Observer Variation ,Physical Examination ,Reproducibility of Results ,Risk Factors ,Syncope ,Public Health and Health Services ,Emergency & Critical Care Medicine ,Clinical sciences - Abstract
ObjectivesClinical prediction models for risk stratification of older adults with syncope or near syncope may improve resource utilization and management. Predictors considered for inclusion into such models must be reliable. Our primary objective was to evaluate the inter-rater agreement of historical, physical examination, and electrocardiogram (ECG) findings in older adults undergoing emergency department (ED) evaluation for syncope or near syncope. Our secondary objective was to assess the level of agreement between clinicians on the patient's overall risk for death or serious cardiac outcomes.MethodsWe conducted a cross-sectional study at 11 EDs in adults 60 years of age or older who presented with unexplained syncope or near syncope. We excluded patients with a presumptive cause of syncope (e.g., seizure) or if they were unable or unwilling to follow-up. Evaluations of the patient's past medical history and current medication use were completed by treating provider and trained research associate pairs. Evaluations of the patient's physical examination and ECG interpretation were completed by attending/resident, attending/advanced practice provider, or attending/attending pairs. All evaluations were blinded to the responses from the other rater. We calculated the percent agreement and kappa statistic for binary variables. Inter-rater agreement was considered acceptable if the kappa statistic was 0.6 or higher.ResultsWe obtained paired observations from 255 patients; mean (±SD) age was 73 (±9) years, 137 (54%) were male, and 204 (80%) were admitted to the hospital. Acceptable agreement was achieved in 18 of the 21 (86%) past medical history and current medication findings, none of the 10 physical examination variables, and three of the 13 (23%) ECG interpretation variables. There was moderate agreement (Spearman correlation coefficient, r = 0.40) between clinicians on the patient's probability of 30-day death or serious cardiac outcome, although as the probability increased, there was less agreement.ConclusionsAcceptable agreement between raters was more commonly achieved with historical rather than physical examination or ECG interpretation variables. Clinicians had moderate agreement in assessing the patient's overall risk for a serious outcome at 30 days. Future development of clinical prediction models in older adults with syncope should account for variability of assessments between raters and consider the use of objective clinical variables.
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- 2016
46. Outcomes and prognostic factors of pediatric patients with a Glasgow Coma Score of 3 after blunt head trauma
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Trimble, Duncan J., Parker, Samantha L., Zhu, Liang, Cox, Charles S., Kitagawa, Ryan S., Fletcher, Stephen A., Sandberg, David I., and Shah, Manish N.
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- 2020
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47. Recruitment and retention of underrepresented populations in Alzheimer's disease research: A systematic review
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Gilmore-Bykovskyi, Andrea L., Jin, Yuanyuan, Gleason, Carey, Flowers-Benton, Susan, Block, Laura M., Dilworth-Anderson, Peggye, Barnes, Lisa L., Shah, Manish N., and Zuelsdorff, Megan
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- 2019
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48. Automating risk stratification for geriatric syndromes in the emergency department
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Haimovich, Adrian D., primary, Shah, Manish N., additional, Southerland, Lauren T., additional, Hwang, Ula, additional, and Patterson, Brian W., additional
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- 2023
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49. Optimal Emergency Department Care Practices for Persons Living With Dementia: A Scoping Review
- Author
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Aggarawal, Neelum T., Allore, Heather, Aloysi, Amy, Belleville, Michael, Bellolio, Fernanda M., Betz, Marian (Emmy), Biese, Kevin, Brandt, Cynthia, Bruursema, Stacey, Carnahan, Ryan, Carpenter, Christopher, Carr, David, Chin-Hansen, Jennie, Daven, Morgan, Degesys, Nida, Dresden, Scott M., Dussetschleger, Jeffrey, Ellenbogen, Michael, Falvey, Jason, Foster, Beverley, Gettel, Cameron, Gifford, Angela, Gilmore-Bykovskyi, Andrea, Goldberg, Elizabeth, Han, Jin, Hardy, James, Hastings, Susan N., Hirshon, Jon M., Hoang, Ly, Hogan, Teresita, Hung, William, Hwang, Ula, Isaacs, Eric, Jaspal, Naveena, Jobe, Deb, Johnson, Jerry, Kelly, Kathleen (Kathy), Kennedy, Maura, Kind, Amy, Leggett, Jesseca, Malone, Michael, Moccia, Michelle, Moreno, Monica, Morrow-Howell, Nancy, Nowroozpoor, Armin, Ohuabunwa, Ugochi, Oiyemhonian, Brenda, Perry, William, Prusaczyk, Beth, Resendez, Jason, Rising, Kristin, Sano, Mary, Savage, Bob, Shah, Manish, Suyama, Joe, Swartzberg, Jeremy, Taylor, Zachary, Tolia, Vaishal, Vann, Allan, Webb, Teresa, Weintraub, Sandra, Serina, Peter, Wescott, Annie B., and Shah, Manish N.
- Published
- 2022
- Full Text
- View/download PDF
50. Emergency Department Communication in Persons Living With Dementia and Care Partners: A Scoping Review
- Author
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Aggarwal, Neelum, Allore, Heather, Aloysi, Amy, Belleville, Michael, Bellolio, M Fernanda, Betz, Marian (Emmy), Biese, Kevin, Brandt, Cynthia, Bruursema, Stacey, Carnahan, Ryan, Carpenter, Christopher, Carr, David, Chin-Hansen, Jennie, Daven, Morgan, Degesys, Nida, Dresden, M Scott, Dussetschleger, Jeffrey, Ellenbogen, Michael, Falvey, Jason, Foster, Beverley, Gettel, Cameron, Gifford, Angela, Gilmore-Bykovskyi, Andrea, Goldberg, Elizabeth, Han, Jin, Hardy, James, Hastings, S. Nicole, Hirshon, Jon Mark, Hoang, Ly, Hogan, Teresita, Hung, William, Hwang, Ula, Isaacs, Eric, Jaspal, Naveena, Jobe, Deb, Johnson, Jerry, Kelly, Kathleen (Kathy), Kennedy, Maura, Kind, Amy, Leggett, Jesseca, Malone, Michael, Moccia, Michelle, Moreno, Monica, Morrow-Howell, Nancy, Nowroozpoor, Armin, Ohuabunwa, Ugochi, Oiyemhonlan, Brenda, Perry, William, Prusaczyk, Beth, Resendez, Jason, Rising, Kristin, Sano, Mary, Savage, Bob, Shah, Manish, Suyama, Joseph, Swartzberg, Jeremy, Taylor, Zachary, Tolia, Vaishal, Vann, Allan, Webb, Teresa, Weintraub, Sandra, Carpenter, Christopher R., Bellolio, Fernanda, Betz, Marian, Carnahan, Ryan M., Doering, Michelle, Hansen, Jennie Chin, Isaacs, Eric D., Jobe, Deborah, Kelly, Kathleen, Suyama, Joe, Vann, Allan S., Rising, Kristin L., and Shah, Manish N.
- Published
- 2022
- Full Text
- View/download PDF
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