464 results on '"Shafer, Timothy"'
Search Results
2. Identification of neural-relevant toxcast high-throughput assay intended gene targets: Applicability to neurotoxicity and neurotoxicant putative molecular initiating events
3. Chemical effects on neural network activity: Comparison of acute versus network formation exposure in microelectrode array assays
4. Identification of neurotoxicology (NT)/developmental neurotoxicology (DNT) adverse outcome pathways and key event linkages with in vitro DNT screening assays
5. In pursuit of precision medicine for brain injury and neurotoxicity and improved protection of human health
6. Assaying Spontaneous Network Activity and Cellular Viability Using Multi-Well Microelectrode Arrays
7. Integration of toxicodynamic and toxicokinetic new approach methods into a weight-of-evidence analysis for pesticide developmental neurotoxicity assessment: A case-study with DL- and L-glufosinate
8. Current status and future directions for a neurotoxicity hazard assessment framework that integrates in silico approaches
9. Developing and applying the adverse outcome pathway concept for understanding and predicting neurotoxicity
10. Application of Microelectrode Array Approaches to Neurotoxicity Testing and Screening
11. Concentration–response evaluation of ToxCast compounds for multivariate activity patterns of neural network function
12. Putative adverse outcome pathways relevant to neurotoxicity
13. A Comparison of In Vitro Points of Departure with Human Blood Levels for Per- and Polyfluoroalkyl Substances (PFAS).
14. Mammalian cell culture models
15. List of contributors
16. A multivariate extension of mutual information for growing neural networks
17. Developmental Neurotoxicity of Pyrethroid Insecticides: Critical Review and Future Research Needs
18. Effects of an environmentally-relevant mixture of pyrethroid insecticides on spontaneous activity in primary cortical networks on microelectrode arrays
19. A multi-laboratory evaluation of microelectrode array-based measurements of neural network activity for acute neurotoxicity testing
20. Calcium Channels: Critical Targets of Toxicants and Diseases
21. Evaluation of Per- and Polyfluoroalkyl Substances (PFAS) In Vitro Toxicity Testing for Developmental Neurotoxicity
22. Pervasive environmental chemicals impair oligodendrocyte development
23. Characterization of Early Cortical Neural Network Development in Multiwell Microelectrode Array Plates
24. In vitro screening of silver nanoparticles and ionic silver using neural networks yields differential effects on spontaneous activity and pharmacological responses
25. Identification of neurotoxicology (NT)/developmental neurotoxicology (DNT) adverse outcome pathways and key event linkages with in vitroDNT screening assays
26. Sensitivity of neuroprogenitor cells to chemical-induced apoptosis using a multiplexed assay suitable for high-throughput screening
27. New Approach Methodologies for Developmental Neurotoxicity Hazard: A case-study with glufosinate
28. Comparisons of Microelectrode Array Acute and Network Formation In Vitro Assays for Evaluating Neurotoxicity
29. Development of a novel approach using the microelectrode array to measure neural activity and network function in larval zebrafish
30. International efforts towards an in vitro battery of developmental neurotoxicity assays for regulatory applications
31. Evaluation of Per- and Poly fluoroalkyl Substances (PFAS) in vitro toxicity testing for developmental neurotoxicity (SOT 23)
32. Evaluation of Per- and Poly fluoroalkyl Substances (PFAS) in vitro toxicity testing for developmental neurotoxicity
33. Increasing the Throughput of a High-Content Imaging-Based Developmental Neurotoxicity Proliferation Assay
34. Application of DNT NAMs Data in Regulatory Scenarios
35. Screening the ToxCast phase II libraries for alterations in network function using cortical neurons grown on multi-well microelectrode array (mwMEA) plates
36. Glufosinate binds N-methyl-d-aspartate receptors and increases neuronal network activity in vitro
37. An expert-driven literature review of “negative” chemicals for developmental neurotoxicity (DNT) in vitro assay evaluation
38. Multi-well microelectrode array recordings detect neuroactivity of ToxCast compounds
39. Burst and principal components analyses of MEA data for 16 chemicals describe at least three effects classes
40. Assaying Spontaneous Network Activity and Cellular Viability Using Multi-well Microelectrode Arrays
41. From the Cover: Developmental Neurotoxicants Disrupt Activity in Cortical Networks on Microelectrode Arrays: Results of Screening 86 Compounds During Neural Network Formation
42. Evaluation of microelectrode array data using Bayesian modeling as an approach to screening and prioritization for neurotoxicity testing
43. Comparison of chemical-induced changes in proliferation and apoptosis in human and mouse neuroprogenitor cells
44. Evaluation of multi-well microelectrode arrays for neurotoxicity screening using a chemical training set
45. Integrating Data From In Vitro New Approach Methodologies for Developmental Neurotoxicity
46. Translational Neurotoxicology - The 17th biennial meeting of the International Neurotoxicology Association
47. Additivity of Pyrethroid Actions on Sodium Influx in Cerebrocortical Neurons in Primary Culture
48. Computational approaches to integrate DNT NAMs for fit-for-purpose identification of DNT hazard (SOT March 2022)
49. Evaluating the bioactivity of the ubiquitous tire preservative 6PPD and its quinone transformation product
50. Computational approaches to integrate DNT NAMs for fit-for-purpose identification of DNT hazard
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