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Your search keyword '"Seyyed Abdolhossein Tavallai Zavareh"' showing total 4 results
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4 results on '"Seyyed Abdolhossein Tavallai Zavareh"'

1. Acute Myocardits Due to Scorpion Sting in a 9-Year-Old Girl

Author

Mohammad Reza Khalilian, Seyyed Abdolhossein Tavallai Zavareh, Ali Reza Norouzi, Mohammad Ghazavi, and Ali Ahmad Goudarzi

Subjects
Myocardits, Stng, Scorpion, Medicine
Abstract

A 9-year-old girl with signs and symptoms of acute toxic myocarditis and cardiogenic shock with elevated cardiac enzymes was admitted to the Critical Care Unit (CCU) of our hospital with an ejection fraction of 25%. The patient was managed with supportive care and the administration of polyvalent antivenom and inotropes, and after 8 days, she was discharged without any complication with normal ejection fraction. Toxic myocarditis can be a result of scorpion envenomation. After two months of follow-up, the patient recovered completely and medications were discontinued.

Published
2021
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2. Hepcidin and HFE Polymorphisms and Ferritin Level in β-Thalassemia Major

Author

Kiavash Fekri, Negar Asle Rasouli, Seyyed Abdolhossein Tavallai Zavareh, Milad Jalil, Fahimeh Moradi, Maryam Hosseinpour, and Hossein Teimori

Subjects
Ferritin, Hepcidin, HFE, Iron overload, Thalassemia, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Background: Thalassemia patients need repeated transfusion that lead to increased blood ferritin level and iron overload in the heart and liver. Because the roles of hepcidin antimicrobial peptide (HAMP) and hemocromatosis protein (HFE) in iron metabolism have been confirmed, this study investigated the effects of these gene's polymorphisms on blood ferritin levels and iron overload in the heart and liver in patients with beta thalassemia major Materials and Methods: This cross-sectional study was conducted on 91 patients referring to the Hajar Hospital in Shahrekord, Iran in 2015. After the blood samples were collected, the ferritin levels were measured, DNA was extracted from the blood cells, and the types of polymorphisms were determined using PCR-RFLP. Data of MRI T2* in the heart and liver were drawn from the patients' medical files. Data analysis was conducted by t-test, chi-square test, Fisher's exact test, and Pearson correlation coefficient. Results: There was no significant correlation between blood ferritin level and c.-582 A>G polymorphisms of hepcidin gene (p=0.58), and H63D of HFE gene (p=0.818). In addition, there was no significant association between the polymorphisms and heart and liver MRI, but there was a significant association between blood ferritin level and qualitative heart and liver MRI (r=-0.34, p=0.035 and r=-0.001, p=0.609, respectively). Conclusion: In patients with β-thalassemia major, the presence of c.-582A>G HAMP and H63D HFE polymorphisms is not effective on blood ferritin level and iron overload in the heart and liver in the studied region.

Published
2019
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3. Hepcidin and

Author

Kiavash, Fekri, Negar, Asle Rasouli, Seyyed Abdolhossein, Tavallai Zavareh, Milad, Jalil, Fahimeh, Moradi, Maryam, Hosseinpour, and Hossein, Teimori

Subjects
congenital, hereditary, and neonatal diseases and abnormalities, Ferritin, Hepcidin, Thalassemia, Original Article, HFE* Iron overload
Abstract

Background: Thalassemia patients need repeated transfusion that lead to increased blood ferritin level and iron overload in the heart and liver. Because the roles of hepcidin antimicrobial peptide (HAMP) and hemocromatosis protein (HFE) in iron metabolism have been confirmed, this study investigated the effects of these gene's polymorphisms on blood ferritin levels and iron overload in the heart and liver in patients with beta thalassemia major Materials and Methods: This cross-sectional study was conducted on 91 patients referring to the Hajar Hospital in Shahrekord, Iran in 2015. After the blood samples were collected, the ferritin levels were measured, DNA was extracted from the blood cells, and the types of polymorphisms were determined using PCR-RFLP. Data of MRI T2* in the heart and liver were drawn from the patients' medical files. Data analysis was conducted by t-test, chi-square test, Fisher's exact test, and Pearson correlation coefficient. Results: There was no significant correlation between blood ferritin level and c.-582 A>G polymorphisms of hepcidin gene (p=0.58), and H63D of HFE gene (p=0.818). In addition, there was no significant association between the polymorphisms and heart and liver MRI, but there was a significant association between blood ferritin level and qualitative heart and liver MRI (r=-0.34, p=0.035 and r=-0.001, p=0.609, respectively). Conclusion: In patients with β-thalassemia major, the presence of c.-582A>G HAMP and H63D HFE polymorphisms is not effective on blood ferritin level and iron overload in the heart and liver in the studied region.

Published
2019

4. Hepcidin and HFE Polymorphisms and Ferritin Level in β-Thalassemia Major

Author

Maryam Hosseinpour, Hossein Teimori, Fahimeh Moradi, Milad Jalil, Seyyed Abdolhossein Tavallai Zavareh, Kiavash Fekri, and Negar Asle Rasouli

Subjects
medicine.medical_specialty, congenital, hereditary, and neonatal diseases and abnormalities, Thalassemia, Hfe gene, BETA THALASSEMIA MAJOR, Gastroenterology, lcsh:RC254-282, 03 medical and health sciences, 0302 clinical medicine, Hepcidin, Internal medicine, Medicine, Transplantation, biology, business.industry, Hematology, Ferritin, HFE, Iron overload, medicine.disease, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Exact test, Oncology, 030220 oncology & carcinogenesis, biology.protein, HAMP, business, β thalassemia major, 030215 immunology
Abstract

Background: Thalassemia patients need repeated transfusion that lead to increased blood ferritin level and iron overload in the heart and liver. Because the roles of hepcidin antimicrobial peptide (HAMP) and hemocromatosis protein (HFE) in iron metabolism have been confirmed, this study investigated the effects of these gene's polymorphisms on blood ferritin levels and iron overload in the heart and liver in patients with beta thalassemia major Materials and Methods: This cross-sectional study was conducted on 91 patients referring to the Hajar Hospital in Shahrekord, Iran in 2015. After the blood samples were collected, the ferritin levels were measured, DNA was extracted from the blood cells, and the types of polymorphisms were determined using PCR-RFLP. Data of MRI T2* in the heart and liver were drawn from the patients' medical files. Data analysis was conducted by t-test, chi-square test, Fisher's exact test, and Pearson correlation coefficient. Results: There was no significant correlation between blood ferritin level and c.-582 A>G polymorphisms of hepcidin gene (p=0.58), and H63D of HFE gene (p=0.818). In addition, there was no significant association between the polymorphisms and heart and liver MRI, but there was a significant association between blood ferritin level and qualitative heart and liver MRI (r=-0.34, p=0.035 and r=-0.001, p=0.609, respectively). Conclusion: In patients with β-thalassemia major, the presence of c.-582A>G HAMP and H63D HFE polymorphisms is not effective on blood ferritin level and iron overload in the heart and liver in the studied region.

Published
2019

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