1,157 results on '"Seyfried, Nicholas T"'
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2. Serum proteomics reveal APOE-ε4-dependent and APOE-ε4-independent protein signatures in Alzheimer’s disease
3. Lowering Hippocampal miR-29a Expression Slows Cognitive Decline and Reduces Beta-Amyloid Deposition in 5×FAD Mice
4. Correction: Network proteomics of the Lewy body dementia brain reveals presynaptic signatures distinct from Alzheimer’s disease
5. Heparin-enriched plasma proteome is significantly altered in Alzheimer’s disease
6. Entorhinal cortex vulnerability to human APP expression promotes hyperexcitability and tau pathology
7. Network proteomics of the Lewy body dementia brain reveals presynaptic signatures distinct from Alzheimer’s disease
8. Native-state proteomics of Parvalbumin interneurons identifies unique molecular signatures and vulnerabilities to early Alzheimer’s pathology
9. OXR1 maintains the retromer to delay brain aging under dietary restriction
10. Cryptic exon inclusion is a molecular signature of LATE-NC in aging brains
11. Author Correction: Serum proteomics reveal APOE-ε4-dependent and APOE-ε4-independent protein signatures in Alzheimer’s disease
12. CSF proteomics identifies early changes in autosomal dominant Alzheimer’s disease
13. Omnibus proteome-wide association study identifies 43 risk genes for Alzheimer disease dementia
14. γ-Secretase activity, clinical features, and biomarkers of autosomal dominant Alzheimer's disease: cross-sectional and longitudinal analysis of the Dominantly Inherited Alzheimer Network observational study (DIAN-OBS)
15. Sex differences in brain protein expression and disease
16. Integrative proteomics identifies a conserved Aβ amyloid responsome, novel plaque proteins, and pathology modifiers in Alzheimer’s disease
17. Proximity Labeling Proteomics Reveals Kv1.3 Potassium Channel Immune Interactors in Microglia
18. INPP5D regulates inflammasome activation in human microglia
19. Integration of plasma and CSF metabolomics with CSF proteomic reveals novel associations between lipid mediators and central nervous system vascular and energy metabolism
20. Quantitative proteomics of cerebrospinal fluid from African Americans and Caucasians reveals shared and divergent changes in Alzheimer’s disease
21. Cerebrospinal fluid proteomics define the natural history of autosomal dominant Alzheimer’s disease
22. Comparison of tau spread in people with Down syndrome versus autosomal-dominant Alzheimer's disease: a cross-sectional study
23. Deconstructing pathological tau by biological process in early stages of Alzheimer disease: a method for quantifying tau spatial spread in neuroimaging
24. Associations of brain morphology with cortical proteins of cognitive resilience
25. Association of plasma and CSF cytochrome P450, soluble epoxide hydrolase, and ethanolamide metabolism with Alzheimer’s disease
26. Mitochondrial Proteostasis Requires Genes Encoded in a Neurodevelopmental Syndrome Locus
27. Identification of State-Specific Proteomic and Transcriptomic Signatures of Microglia-Derived Extracellular Vesicles
28. Unique molecular characteristics and microglial origin of Kv1.3 channel–positive brain myeloid cells in Alzheimer’s disease
29. Unbiased classification of the elderly human brain proteome resolves distinct clinical and pathophysiological subtypes of cognitive impairment
30. Cell-type-specific regulation of APOE and CLU levels in human neurons by the Alzheimer’s disease risk gene SORL1
31. Multi-omic characterization of brain changes in the vascular endothelial growth factor family during aging and Alzheimer's disease
32. Cellular Proteomic Profiling Using Proximity Labeling by TurboID-NES in Microglial and Neuronal Cell Lines
33. Identification of Conserved Proteomic Networks in Neurodegenerative Dementia
34. Translational animal models for Alzheimer's disease: An Alzheimer's Association Business Consortium Think Tank
35. CSF proteome profiling across the Alzheimer’s disease spectrum reflects the multifactorial nature of the disease and identifies specific biomarker panels
36. Comparison of amyloid burden in individuals with Down syndrome versus autosomal dominant Alzheimer's disease: a cross-sectional study
37. Proteins linking APOE ɛ4 with Alzheimer's disease
38. Integrating human brain proteomes with genome-wide association data implicates novel proteins in post-traumatic stress disorder
39. Systems Analysis of the 22q11.2 Microdeletion Syndrome Converges on a Mitochondrial Interactome Necessary for Synapse Function and Behavior
40. Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia
41. Proximity-based labeling reveals DNA damage–induced phosphorylation of fused in sarcoma (FUS) causes distinct changes in the FUS protein interactome
42. Predicting brain age from functional connectivity in symptomatic and preclinical Alzheimer disease
43. APP and DYRK1A regulate axonal and synaptic vesicle protein networks and mediate Alzheimer’s pathology in trisomy 21 neurons
44. Cell type-specific biotin labeling in vivo resolves regional neuronal and astrocyte proteomic differences in mouse brain
45. SAMHD1 deacetylation by SIRT1 promotes DNA end resection by facilitating DNA binding at double-strand breaks
46. Elevated ganglioside GM2 activator (GM2A) in human brain tissue reduces neurite integrity and spontaneous neuronal activity
47. Brain microRNAs are associated with variation in cognitive trajectory in advanced age
48. Quantitative proteomic analysis of the lysine acetylome reveals diverse SIRT2 substrates
49. Shared mechanisms across the major psychiatric and neurodegenerative diseases
50. Multi-platform proteomic analysis of Alzheimer’s disease cerebrospinal fluid and plasma reveals network biomarkers associated with proteostasis and the matrisome
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