Search

Your search keyword '"Seyfrid, Mathieu"' showing total 14 results
Start Over Author "Seyfrid, Mathieu"
14 results on '"Seyfrid, Mathieu"'

1. The Rational Development of CD133-Targeting Immunotherapies for Glioblastoma

Author

Vora, Parvez, Venugopal, Chitra, Salim, Sabra Khalid, Tatari, Nazanin, Bakhshinyan, David, Singh, Mohini, Seyfrid, Mathieu, Upreti, Deepak, Rentas, Stefan, Wong, Nicholas, Williams, Rashida, Qazi, Maleeha Ahmad, Chokshi, Chirayu, Ding, Avrilynn, Subapanditha, Minomi, Savage, Neil, Mahendram, Sujeivan, Ford, Emily, Adile, Ashley Ann, McKenna, Dillon, McFarlane, Nicole, Huynh, Vince, Wylie, Ryan Gavin, Pan, James, Bramson, Jonathan, Hope, Kristin, Moffat, Jason, and Singh, Sheila

Published
2020
Full Text
View/download PDF

2. Bmi1 regulates human glioblastoma stem cells through activation of differential gene networks in CD133+ brain tumor initiating cells

Author

Vora, Parvez, Seyfrid, Mathieu, Venugopal, Chitra, Qazi, Maleeha A., Salim, Sabra, Isserlin, Ruth, Subapanditha, Minomi, O’Farrell, Erin, Mahendram, Sujeivan, Singh, Mohini, Bakhshinyan, David, Chokshi, Chirayu, McFarlane, Nicole, Dvorkin-Gheva, Anna, Brown, Kevin R., Murty, Naresh, Moffat, Jason, Bader, Gary D., and Singh, Sheila K.

Published
2019
Full Text
View/download PDF

4. Stem cell-associated heterogeneity in Glioblastoma results from intrinsic tumor plasticity shaped by the microenvironment

Author

Dirkse, Anne, Golebiewska, Anna, Buder, Thomas, Nazarov, Petr V., Muller, Arnaud, Poovathingal, Suresh, Brons, Nicolaas H. C., Leite, Sonia, Sauvageot, Nicolas, Sarkisjan, Dzjemma, Seyfrid, Mathieu, Fritah, Sabrina, Stieber, Daniel, Michelucci, Alessandro, Hertel, Frank, Herold-Mende, Christel, Azuaje, Francisco, Skupin, Alexander, Bjerkvig, Rolf, Deutsch, Andreas, Voss-Böhme, Anja, and Niclou, Simone P.

Published
2019
Full Text
View/download PDF

5. Dual Antigen T Cell Engagers Targeting CA9 as an Effective Immunotherapeutic Modality for Targeting CA9 in Solid Tumors

Author

Tatari, Nazanin, primary, Zhang, Xiaoyu, additional, Chafe, Shawn C., additional, McKenna, Dillon, additional, Lawson, Keith A., additional, Subapanditha, Minomi, additional, Shaikh, Muhammad Vaseem, additional, Seyfrid, Mathieu, additional, Savage, Neil, additional, Venugopal, Chitra, additional, Moffat, Jason, additional, and Singh, Sheila K., additional

Published
2022
Full Text
View/download PDF

6. CD70 as an actionable immunotherapeutic target in recurrent glioblastoma and its microenvironment

Author

Seyfrid, Mathieu, primary, Maich, William Thomas, additional, Shaikh, Muhammad Vaseem, additional, Tatari, Nazanin, additional, Upreti, Deepak, additional, Piyasena, Deween, additional, Subapanditha, Minomi, additional, Savage, Neil, additional, McKenna, Dillon, additional, Mikolajewicz, Nicholas, additional, Han, Hong, additional, Chokshi, Chirayu, additional, Kuhlmann, Laura, additional, Khoo, Amanda, additional, Salim, Sabra Khalid, additional, Archibong-Bassey, Blessing, additional, Gwynne, William, additional, Brown, Kevin, additional, Murtaza, Nadeem, additional, Bakhshinyan, David, additional, Vora, Parvez, additional, Venugopal, Chitra, additional, Moffat, Jason, additional, Kislinger, Thomas, additional, and Singh, Sheila, additional

Published
2022
Full Text
View/download PDF

7. Temporal profiling of therapy resistance in human medulloblastoma identifies novel targetable drivers of recurrence

Author

Bakhshinyan, David, primary, Adile, Ashley A., additional, Liu, Jeff, additional, Gwynne, William D., additional, Suk, Yujin, additional, Custers, Stefan, additional, Burns, Ian, additional, Singh, Mohini, additional, McFarlane, Nicole, additional, Subapanditha, Minomi K., additional, Qazi, Maleeha A., additional, Vora, Parvez, additional, Kameda-Smith, Michelle M., additional, Savage, Neil, additional, Desmond, Kim L., additional, Tatari, Nazanin, additional, Tran, Damian, additional, Seyfrid, Mathieu, additional, Hope, Kristin, additional, Bock, Nicholas A., additional, Venugopal, Chitra, additional, Bader, Gary D., additional, and Singh, Sheila K., additional

Published
2021
Full Text
View/download PDF

8. Abstract 570: A glioblastoma translational pipeline: discovery of novel tumor antigens that drive GBM recurrence

Author

Vora, Parvez, primary, Venugopal, Chitra, additional, Chokshi, Chirayu, additional, Qazi, Maleeha, additional, Tatari, Nazanin, additional, Brown, Kevin, additional, Yelle, Nicholas, additional, Adams, Jarrett, additional, Tieu, David, additional, Seyfrid, Mathieu, additional, Singh, Mohini, additional, Savage, Neil, additional, Subapanditha, Minomi, additional, Bakhshinyan, David, additional, Kuhlmann, Laura, additional, Kislinger, Thomas, additional, Sidhu, Sachdev, additional, Moffat, Jason, additional, and Singh, Sheila Kumari, additional

Published
2019
Full Text
View/download PDF

9. Stem Cell-Associated Heterogeneity in Glioblastoma Is a Result of Intrinsic Tumor Plasticity Shaped by the Microenvironment

Author

Dirkse, Anne, primary, Golebiewska, Anna, additional, Buder, Thomas, additional, Nazarov, Petr V., additional, Muller, Arnaud, additional, Poovathingal, Suresh, additional, Brons, Nicolaas H.C., additional, Leite, Sonia, additional, Sauvageot, Nicolas, additional, Sarkisjan, Dzjemma, additional, Seyfrid, Mathieu, additional, Fritah, Sabrina, additional, Stieber, Daniel, additional, Michelucci, Alessandro, additional, Herold-Mende, Christel, additional, Bjerkvig, Rolf, additional, Azuaje, Francisco, additional, Skupin, Alexander, additional, Deutsch, Andreas, additional, Voss-BBhme, Anja, additional, and Niclou, Simone, additional

Published
2018
Full Text
View/download PDF

10. TMOD-06. CLONAL DYNAMICS OF HUMAN GLIOBLASTOMA IN RESPONSE TO CHEMORADIOTHERAPY

Author

Qazi, Maleeha, primary, Nixon, Allison, additional, Bakhshinyan, David, additional, Venugopal, Chitra, additional, Vora, Parvez, additional, Brown, Kevin, additional, Subapanditha, Minomi, additional, Yelle, Nicolas, additional, Chokshi, Chirayu, additional, Seyfrid, Mathieu, additional, Moffat, Jason, additional, and Singh, Sheila, additional

Published
2017
Full Text
View/download PDF

14. In Vitro Self-Renewal Assays for Brain Tumor Stem Cells.

Author

Seyfrid M, Bobrowski D, Bakhshinyan D, Tatari N, Venugopal C, and Singh SK

Subjects
Cell Line, Tumor, Humans, Regression Analysis, Biological Assay methods, Brain Neoplasms pathology, Cell Self Renewal, Neoplastic Stem Cells pathology
Abstract

Early development of human organisms relies on stem cells, a population of non-specialized cells that can divide symmetrically to give rise to two identical daughter cells, or divide asymmetrically to produce one identical daughter cell and another more specialized cell. The capacity to undergo cellular divisions while maintaining an undifferentiated state is termed self-renewal and is responsible for the maintenance of stem cell populations during development. In addition, self-renewal plays a crucial role in the homeostasis of developed organism through replacement of defective cells.Similar to their non-malignant counterparts, it has been postulated that tumor cells follow a differentiation hierarchy, with the least differentiated cells termed cancer stem cells (CSCs) at the apex. These tumor stem cells possess the ability to self-renew, have a higher capacity to initiate tumor growth when xenografted into an animal model, and can recapitulate the cell heterogeneity of the tumor they originate from. Hence, further investigation of mechanisms governing the self-renewal in cancer can lead to development of novel therapies targeting CSCs.In this chapter, we described the soft agar assay and the limiting dilution assay (LDA) as two easy-to-implement and inexpensive assays to measure the stemness properties of brain tumor stem cells (BTSCs). These techniques constitute useful tools for the preclinical evaluation of therapeutic strategies targeting BTSCs clonogenicity.

Published
2019
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results