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Introduction and purpose: The article focuses on the analysis of young people's awareness of the consumption of energy drinks, especially those containing caffeine. The aim of the study is to understand the level of knowledge about the awareness and consumption of energy drinks among students aged 18-25. This study was conducted using surveys and involving 202 participants. Material and Methods: The study was conducted using online anonymous surveys, involving 202 participants. The participants were students aged 18-25 both women and men. The results were analyzed according to the age and gender. Moreover, based on the available literature examining aspects related to the consumption of energy drinks. Results: The study shows that the vast majority of respondents (94.06%) are aware of the impact of energy substances on the body. The charts also illustrate that caffeine, as the main ingredient in energy drinks, is well understood in terms of cardiovascular effects. Moreover, the student community is aware of the link between excessive sugar consumption and the risk of cancer development. Discussion: The study shows that young people are aware of the negative impact of energy drinks on health. Nevertheless, not all areas of knowledge are clear to them. The continuous increase in the level of education can undoubtedly contribute to the introduction of healthy eating habits among students. Most respondents declare to drink energy drinks again, it should draw our special attention. Conclusions: It is worth noting the need for further education, especially in the field of metabolic syndrome. It also highlights the role of research and education in shaping public health awareness. Finally, the article suggests that further research and targeted educational programs are critical to improving public health, especially in the context of energy drink consumption.

Introduction and aim: Adenoma pleomorphum (multiform adenoma) is the most popular bening tumor, that originates from the salivary glands. Neoplasm develops mainly from large salivary glands and its occurrence in the nasal cavity is rare and falls mainly in the 3-6 decade of life. Only 1% of all pleomorphic adenomas develop in the nasal and sinus cavities. Despite being a benign tumor, malignant transformation can occur in 2-10% of cases. Description of the case: We report a case of a 21-year-old female ethnically Polish patient with nasal multiform adenoma with initial diagnosis, which indicated a polyp. The final diagnosis was based on the histopathological examination of the resected lesion. The tumor was removed by an endoscopic method with no tissue margins, which may increase the risk of recurrence. Conclusions: Our case demonstrates that despite pleomorphic adenomas typically occurs in the 3rd to 6th decade of life, clinical symptoms are nondistinctive with a polyp and nasal cavity is a very rare location there should be always be increased vigilance leading to choosing best diagnostic measures to form right diagnosis.

Introduction and purpose: Hereditary hemorrhagic telangiectasia (HHT), also known as Osler-Weber-Rendu syndrome, is a rare and complex vascular disorder characterized by abnormal blood vessel formation. It can present significant challenges in diagnosis and management, as it is currently estimated up to 90% of those affected are never diagnosed. Despite its rarity, HHT can carry substantial implications for patients and their families, at times requiring comprehensive medical care and support. This paper aims to provide an in-depth exploration of HHT, encompassing its epidemiology, genetics, clinical manifestations, diagnostic approaches, and current management strategies. Moreover, we hope to point out possible areas in need of future research. Description of the state knowledge: HHT is an autosomal dominant genetic disorder that affects 1 in 5-10,000 people. Its most prominent symptoms include telangiectasia of skin and mucous membranes, recurrent epistaxis, gastrointestinal bleeding and arteriovenous malformations in vital organs. In the vast majority of cases, it is caused by a mutation in one of the following genes: ENG, ACVRL1, SMAD4; however, mutations in other genes have been described to cause a similar or much the same constellation of symptoms. Treatment options are focused on managing symptoms and improving quality of life, but possible new treatment options are being researched that could change the landscape of HHT management. Summary: HHT is a severely underdiagnosed disease that has seen a surge of researchers’ interest in recent years. We firmly believe that, combined with plummeting costs of genetic testing and possible new treatment options, means that HHT will become increasingly important in physicians’ everyday practice.

Introduction and purpose: Breast cancer poses a significant global health challenge, especially in Poland, where it is the most prevalent cancer among women. Despite advancements in medical technology, individual awareness and proactive health practices, such as Breast Self-Examination (BSE), are crucial for early detection. This study focuses on BSE practices in the Tarnów district of Poland, a small city facing unique healthcare challenges, to understand the prevalence, knowledge, and attitudes toward BSE. The aim of study was to comprehensively investigate BSE practices among women in the Tarnów district, considering socio-demographic factors. Material and Methods: Anonymous questionnaires assessed socio-demographic characteristics, attitudes toward BSE, frequency of BSE performance, knowledge on BSE, and sources of information. The survey involved 100 Polish women in gynecologist and general practitioner offices in Tarnów County. Results were analyzed in relation to age, education, and place of residence. Results: While 90% of women were familiar with BSE, 10% had never heard of it. While 29% performed BSE monthly, 18% never conducted the examination. Knowledge gaps were identified, particularly regarding optimal BSE practices. Information sources included the Internet (44%) and gynecologists (28%). Notably, 65% expressed a willingness to participate in BSE training. Conclusions: In conclusion, the study provides valuable insights into BSE practices among women in the Tarnów district, emphasizing the need for targeted interventions to encourage regular BSE. Knowledge gaps and the willingness of women to participate in training present opportunities for healthcare initiatives. The study also highlights the need for broader health education campaigns to dispel myths and enhance awareness, particularly regarding breast cancer affecting both genders. Limitations include a small sample size and geographic specificity to Tarnów district.

Introduction: Diabetes poses a significant global health challenge, impacting patient well-being and longevity. Despite advances in diagnosis and treatment, the prevalence of diabetes continues to rise, with projections indicating a substantial increase in affected individuals in the coming years. The complications of diabetes, including cardiovascular disease, retinopathy, nephropathy, and neuropathy, underscore the importance of early detection and management. In this context, artificial intelligence (AI) offers promising opportunities to revolutionize diabetes care, enabling faster diagnostics, more effective treatment strategies. Description of the State of Knowledge: Artificial intelligence (AI) has emerged as a transformative force in healthcare, leveraging machine learning and deep learning algorithms to analyze vast amounts of medical data. These algorithms enable more accurate diagnosis, prediction of disease onset, and early detection of complications associated with diabetes. Machine learning models, including support vector machines and neural networks, have shown promise in identifying diabetes risk factors and predicting disease progression. Deep learning techniques, with their ability to analyze complex data patterns, offer further insights into diabetes diagnosis. Additionally, fuzzy cognitive maps provide a framework for decision-making based on patient data, enhancing early detection efforts. Summary: Artificial intelligence holds immense potential to transform diabetes care, offering solutions for early detection, personalized treatment, and improved patient outcomes. By harnessing the power of AI algorithms, healthcare providers can enhance diagnostic accuracy, predict disease progression, and implement targeted interventions.

Introduction and purpose: Diabetes has emerged as a global lifestyle disease, with an alarming rise in cases, particularly of type 2 diabetes. In Poland, over 3 million people are diagnosed, and an estimated 4 million cases are expected by 2030. Effective treatment involves a multifaceted approach, including dietary intervention, physical activity, and pharmacological options. Incretins, such as glucagon-like peptide-1 (GLP-1), play a pivotal role in carbohydrate metabolism regulation, and GLP-1 analogs have become essential in managing type 2 diabetes. This paper explores the development and mechanisms of GLP-1 analogs, detailing their impact on insulin secretion, gastric emptying, and weight reduction. Description of the state knowledge: Various GLP-1 receptor agonists, including exenatide, liraglutide, dulaglutide, semaglutide, and the novel tirzepatide, are discussed. These drugs exhibit diverse pharmacokinetics, modes of administration, and effects on glucose metabolism and weight. Despite their efficacy, there is a concerning trend of off-label use, particularly for obesity treatment, leading to shortages for patients with valid prescriptions. This misuse is fueled by para-advertising on social media platforms, contributing to a surge in prescriptions and reimbursement costs. To address this, guidelines for GLP-1 analog use in obesity treatment are proposed, emphasizing the need for a stable drug supply and normalizing drug availability. Summary: In 2023, concerns intensified with reports of counterfeit GLP-1 analogs, prompting regulatory interventions. The paper concludes by underscoring the critical role GLP-1 analogs play in diabetes and obesity treatment, while emphasizing the importance of responsible prescription practices, guidelines adherence, and regulatory vigilance to ensure patient safety and mitigate the risks associated with misuse and counterfeit drugs.

Introduction and purpose: Palliative care is designed to ensure proper comfort in living and dying, primarily by alleviating suffering in patients for whom medical interventions have proved ineffective. In situations where suffering is unbearable, palliative care offers "last resort" treatment, namely palliative sedation. This involves the intentional administration of sedative drugs to the patient to reduce the level of consciousness, even inducing sleep, in order to control suffering caused by conditions that are resistant to other treatments. The aim of this article is to present various perspectives on palliative sedation. Description of the state knowledge: Topics discussed include: cessation of hydration and nutrition, loss of patient control over decision-making in treatment progression after the induction of pharmacological coma, the principle of double effect, complications arising from the use of indiscriminate polypharmacy, and views on life shortening through palliative sedation or its comparison to euthanasia. The distinction between palliative sedation and euthanasia is explored, with arguments on both sides contributing to ongoing debates. The paper concludes by advocating for comprehensive guidelines and interdisciplinary assessments to ensure ethical and patient-centered decision-making in the application of palliative sedation in terminally ill patients. Summary: A discussion is necessary on the creation of acceptable and appropriate procedures that would not arouse the controversies currently associated with the use of palliative sedation.