1,462 results on '"Severinov, Konstantin"'
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2. Author Correction: A virally encoded tRNA neutralizes the PARIS antiviral defence system
3. Interference Requirements of Type III CRISPR-Cas Systems from Thermus thermophilus
4. Benchmarking DNA isolation methods for marine metagenomics
5. Persistence of plasmids targeted by CRISPR interference in bacterial populations
6. Non-homologous dsODN increases the mutagenic effects of CRISPR-Cas9 to disrupt oncogene E7 in HPV positive cells
7. Prespacers formed during primed adaptation associate with the Cas1–Cas2 adaptation complex and the Cas3 interference nuclease–helicase
8. Single-molecule studies reveal the off-pathway early paused state intermediates as a target of streptolydigin inhibition of RNA polymerase and its dramatic enhancement by Gre factors.
9. Trojan horse peptide conjugates remodel the activity spectrum of clinical antibiotics.
10. Optimal number of spacers in CRISPR arrays
11. Sxt1, Isolated from a Therapeutic Phage Cocktail, Is a Broader Host Range Relative of the Phage T3.
12. Bacteriostatic antibiotics promote CRISPR-Cas adaptive immunity by enabling increased spacer acquisition
13. Development of ONT-cappable-seq to unravel the transcriptional landscape of Pseudomonas phages
14. Structural basis of template strand deoxyuridine promoter recognition by a viral RNA polymerase
15. Interaction between transcribing RNA polymerase and topoisomerase I prevents R-loop formation in E. coli
16. Liquid drop of DNA libraries reveals total genome information
17. The bacteriophage LUZ24 “Igy” peptide inhibits the Pseudomonas DNA gyrase
18. Type III CRISPR-Cas Systems: Deciphering the Most Complex Prokaryotic Immune System
19. Identification and characterization of andalusicin: N-terminally dimethylated class III lantibiotic from Bacillus thuringiensis sv. andalousiensis
20. The role of prokaryotic argonautes in resistance to type II topoisomerases poison ciprofloxacin.
21. New Viruses Infecting Hyperthermophilic Bacterium Thermus thermophilus.
22. An effective vaginal gel to deliver CRISPR/Cas9 system encapsulated in poly (β-amino ester) nanoparticles for vaginal gene therapy
23. In vitro and in vivo growth inhibition of human cervical cancer cells via human papillomavirus E6/E7 mRNAs’ cleavage by CRISPR/Cas13a system
24. Hyperbranched poly(β-amino ester) based polyplex nanopaticles for delivery of CRISPR/Cas9 system and treatment of HPV infection associated cervical cancer
25. Quantification of the affinities of CRISPR–Cas9 nucleases for cognate protospacer adjacent motif (PAM) sequences
26. Molecular basis of foreign DNA recognition by BREX anti-phage immunity system
27. The effect of pseudoknot base pairing on cotranscriptional structural switching of the fluoride riboswitch
28. RecA-dependent or independent recombination of plasmid DNA generates a conflict with the host EcoKI immunity by launching restriction alleviation
29. Microbial Arsenal of Antiviral Defenses. Part II
30. Natural diversity of CRISPR spacers of Thermus : evidence of local spacer acquisition and global spacer exchange
31. Structure and function of virion RNA polymerase of a crAss-like phage
32. Transcriptome-wide detection of RNA cleavage sites revealed tRNA cleavage by target-activated CRISPR-Cas13a effector
33. Tail-Tape-Fused Virion and Non-Virion RNA Polymerases of a Thermophilic Virus with an Extremely Long Tail
34. Xenogeneic Regulation of the Bacterial Transcription Machinery
35. Cytological Immunostaining of HMGA2, LRP1B, and TP63 as Potential Biomarkers for Triaging Human Papillomavirus-Positive Women
36. Tail-tape-fused virion and non-virion RNA polymerases of a thermophilic virus with an extremely long tail
37. Viral proteins activate PARIS-mediated tRNA degradation and viral tRNAs rescue infection
38. The pearl jubilee of microcin J25: thirty years of research on an exceptional lasso peptide
39. Cryo-EM structure and in vitro DNA packaging of a thermophilic virus with supersized T=7 capsids
40. Architecture of Microcin B17 Synthetase: An Octameric Protein Complex Converting a Ribosomally Synthesized Peptide into a DNA Gyrase Poison
41. Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
42. Characterization ofStreptococcus uberisCas9 (SuCas9) – a Type II-A Ortholog Functional in Human Cells
43. The Effect of Pseudoknot Base Pairing on Cotranscriptional Structural Switching of the Fluoride Riboswitch
44. Ultrahigh-throughput functional profiling of microbiota communities
45. Systematic prediction of genes functionally linked to CRISPR-Cas systems by gene neighborhood analysis
46. Systematic prediction of functionally linked genes in bacterial and archaeal genomes
47. The Interaction between σ 70 and the β-Flap of Escherichia coli RNA Polymerase Inhibits Extension of Nascent RNA during Early Elongation
48. Interdependencies Between the Adaptation and Interference Modules Guide Efficient CRISPR-Cas Immunity
49. The Role of RNA Polymerase σ Subunit in Promoter-Independent Initiation of Transcription
50. Mechanism of duplex DNA destabilization by RNA-guided Cas9 nuclease during target interrogation
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