654 results on '"Seung-min Park"'
Search Results
2. Optical nanomaterial-based detection of biomarkers in liquid biopsy
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Young Jun Kim, Won-Yeop Rho, Seung-min Park, and Bong-Hyun Jun
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Liquid biopsy ,Optical nanoparticles ,Circulating tumor markers ,Circulating tumor cells ,Circulating exosomes ,Circulating tumor DNAs ,Diseases of the blood and blood-forming organs ,RC633-647.5 ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Abstract Liquid biopsy, which is a minimally invasive procedure as an alternative to tissue biopsy, has been introduced as a new diagnostic/prognostic measure. By screening disease-related markers from the blood or other biofluids, it promises early diagnosis, timely prognostication, and effective treatment of the diseases. However, there will be a long way until its realization due to its conceptual and practical challenges. The biomarkers detected by liquid biopsy, such as circulating tumor cell (CTC) and circulating tumor DNA (ctDNA), are extraordinarily rare and often obscured by an abundance of normal cellular components, necessitating ultra-sensitive and accurate detection methods for the advancement of liquid biopsy techniques. Optical biosensors based on nanomaterials open an important opportunity in liquid biopsy because of their enhanced sensing performance with simple and practical properties. In this review article, we summarized recent innovations in optical nanomaterials to demonstrate the sensitive detection of protein, peptide, ctDNA, miRNA, exosome, and CTCs. Each study prepares the optical nanomaterials with a tailored design to enhance the sensing performance and to meet the requirements of each biomarker. The unique optical characteristics of metallic nanoparticles (NPs), quantum dots, upconversion NPs, silica NPs, polymeric NPs, and carbon nanomaterials are exploited for sensitive detection mechanisms. These recent advances in liquid biopsy using optical nanomaterials give us an opportunity to overcome challenging issues and provide a resource for understanding the unknown characteristics of the biomarkers as well as the mechanism of the disease. Graphical abstract
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- 2024
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3. Complete mitochondrial genome of the razor-backed musk turtle (Sternotherus carinatus, testudines: emydidae) in Korea
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Jaehong Park, Seung-Ju Cheon, Jae-Hyuk Choi, Seung-Min Park, Ha-Cheol Sung, and Dong-Hyun Lee
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Sternotherus carinatus ,emydidae ,mitochondrial genome ,Genetics ,QH426-470 - Abstract
AbstractSternotherus carinatus has been considered as a potential invasive species in Korea. However, the mitochondrial genome information of S. carinatus which can be used to control its effect on ecosystem is lacking. In this study, the complete mitochondrial genome of S. carinatus in Korea was sequenced and characterized. The mitochondrial genome consists of 37 genes (13 protein-coding genes, 22 transfer RNA genes, and 2 ribosomal RNA genes) and a noncoding region. Phylogenetic analysis based on the mitochondrial genome sequences showed that S. carinatus from Korea is separated from other turtles which are the invasive species in Korea. Sequence divergence calculations indicated near-zero divergence between S. carinatus populations in Korea, the USA, and China, suggesting limited genetic differentiation. In the context of the broader issue of invasive species disrupting ecosystems, this research contributes to the identification of mitochondrial genomes for various freshwater turtle species, emphasizing the need for extended data collection to discern genetic mixing trends between native and non-native species. This study is a significant step toward managing S. carinatus as a potential invasive species in Korea.
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- 2023
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4. Complete mitochondrial genome of the western painted turtle (Chrysemys picta bellii, Testudines: Emydidae) in Korea
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Jaehong Park, Seung-Min Park, Jae-Hyuk Choi, Ha-Cheol Sung, and Dong-Hyun Lee
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Chrysemys picta bellii ,Emydidae ,mitochondrial genome ,Genetics ,QH426-470 - Abstract
AbstractThe complete mitochondrial genome of Chrysemys picta bellii in Korea was sequenced and characterized. The mitochondrial genome consists of 37 genes (13 protein-coding genes, 22 transfer RNA genes, and 2 ribosomal RNA genes) and a noncoding region. Phylogenetic analysis based on the mitochondrial genome sequences revealed that C. p. bellii from Korea formed a cluster with C. p. bellii from China and C. picta from the USA, while showing clear separation from other turtle species within the C. picta cluster. This study presented the first complete mitochondrial genome from C. p. bellii in Korea, offering crucial information for managing invasive species and protecting the local ecosystem.
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- 2023
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5. The first record of leucism in the Rhabdophis tigrinus (Boie, 1826) (Squamata, Colubridae) in South Korea
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Seung‐Min Park, Seung‐Ju Cheon, Hye‐Rin Park, Na‐Yeong Kim, Md Mizanur Rahman, and Ha‐Cheol Sung
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abnormal color variation ,ecdysis ,normal eyes ,tiger keelback ,yellowish snake ,Ecology ,QH540-549.5 - Abstract
Abstract Leucism, in which pigmentation is lost over part or the entire body of an animal, has a range of possible genetic causes. Here, we report leucism in an individual tiger keelback (Rhabdophis tigrinus) found on Jeung Island, Shinan‐gun, Jeollanam‐do, South Korea, during a survey of the distribution of reptiles in the area. The individual was observed sunbathing in the bushes next to a pond. This individual exhibited ecdysis, thus it considered that have normal feeding activity. Our report represents the first observation of leucism in R. tigrinus, and thus, further analysis is needed of this phenotype to more clearly understand its impact on the species and its natural history.
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- 2024
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6. Population-level call properties of endangered Dryophytes suweonensissensu lato (Anura: Amphibia) in South Korea
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Md Mizanur Rahman, Jiyoung Yun, KaHyun Lee, Seung-Ha Lee, Seung-Min Park, Choong-Ho Ham, and Ha-Cheol Sung
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Dryophytes flaviventris ,Taxonomy ,Chilgap mountain ,Species-level call variation ,Temporal call properties ,Medicine ,Biology (General) ,QH301-705.5 - Abstract
Calling is one of the unique amphibian characteristics that facilitates social communication and shows individuality; however, it also makes them vulnerable to predators. Researchers use amphibian call properties to study their population status, ecology, and behavior. This research scope has recently broadened to species identification and taxonomy. Dryophytes flaviventris has been separated from the endangered anuran species, D. suweonensis, based on small variations in genetic, morphometric, and temporal call properties observed in South Korea. The Chilgap Mountain (CM) was considered as the potential geographic barrier for the speciation. However, it initiated taxonomic debates as CM has been hardly used and is considered a potential barrier for other species. The calls of populations from both sides are also apparently similar. Thus, to verify the differences in call properties among populations of D. suweonensis sensu lato (s.l.; both of the species), we sampled and analyzed call data from five localities covering its distribution range, including the southern (S) and northern (N) parts of CM. We found significant differences in many call properties among populations; however, no specific pattern was observed. Some geographically close populations, such as Iksan (S), Wanju (S), and Gunsan (S), had significant differences, whereas many distant populations, such as Pyeongtaek (N) and Wanju (S), had no significant differences. Considering the goal of this study was only to observe the call properties, we cautiously conclude that the differences are at the population level rather than the species level. Our study indicates the necessity of further investigation into the specific status of D. flaviventris using robust integrated taxonomic approaches, including genetic and morphological parameters from a broader array of localities.
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- 2023
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7. The first record of an invasive reptile species, Pelomedusa cf. olivacea (Schweigger, 1812) (Pelomedusidae, Testudines), in the wild of South Korea
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Seung-Min Park, Md Mizanur Rahman, Choong-Ho Ham, and Ha-Cheol Sung
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African Helmeted Turtle ,Hongje Stream ,Mauremy ,Biology (General) ,QH301-705.5 - Abstract
Invasive species are of global conservation concern. South Korea is also facing the same challenge, especially, due to the growing pet trade. Herein, we report Pelomedusa cf. olivacea (Schweigger, 1812) from the wild in South Korea, where it has been imported as a pet. This is the first record of Pelomedusa in the Asian continent. In October 2019, we found an individual of this species beside Hongje Stream in Seoul. We recommend immediate control measures and strict monitoring of the pet trade to avoid the introduction of more invasive species.
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- 2022
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8. Efficient Analysis of Small Molecules via Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (LDI–TOF MS) Using Gold Nanoshells with Nanogaps
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Noori Kim, Yoon-Hee Kim, Gaon Jo, Jin Yoo, Seung-min Park, Bong-Hyun Jun, and Woon-Seok Yeo
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matrix-assisted laser desorption/ionization time-of-flight mass spectrometry ,gold nanoshell ,nanogap ,surface-assisted laser desorption/ionization ,silica core nanoparticle ,small-molecule analysis ,Chemistry ,QD1-999 - Abstract
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI–TOF MS) is a commonly used technique for analyzing large biomolecules. However, the utilization of organic matrices limits the small-molecule analysis because of the interferences in the low-mass region and the reproducibility issues. To overcome these limitations, a surface-assisted laser desorption/ionization (SALDI), which utilizes nanostructured metallic surfaces, has been developed. Herein, a novel approach for SALDI–MS was proposed using silica@gold core–shell hybrid materials with a nanogap-rich shell (SiO2@Au NGS), which is an emerging material due to its excellent heat-generating capabilities. The gold shell thickness was controlled by adjusting the concentration of gold precursor for the growth of gold nanoparticles. SALDI-MS measurements were performed on a layer formed by drop-casting a mixture of SiO2@Au NGS and analytes. At the optimized process, the gold shell thickness was observed to be 17.2 nm, which showed the highest absorbance. Based on the enhanced SALDI capability, SiO2@Au NGS was utilized to detect various small molecules, including amino acids, sugars, and flavonoids, and the ionization softness was confirmed with a survival yield upon fragmentation. The limits of detection, reproducibility, and salt tolerance of SiO2@Au NGS demonstrate its potential as an effective and reliable SALDI material for small-molecule analyses.
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- 2023
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9. Risk assessment for the native anurans from an alien invasive species, American bullfrogs (Lithobates catesbeianus), in South Korea
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Hye-Rin Park, Md Mizanur Rahman, Seung-Min Park, Jae-Hyeok Choi, Hee-Jin Kang, and Ha-Cheol Sung
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Medicine ,Science - Abstract
Abstract The invasive species are of global concern, and the Invasive American Bullfrog (IAB; Lithobates catesbeianus) is one of the worst invasive amphibian species worldwide. Like other countries, South Korea is also facing challenges from IAB. Although many studies indicated impacts of IAB on native anurans in Korea, the actual risk at the specific level is yet to evaluate. Considering the putative invasiveness of IAB, it is hypothesized that any species with the possibility of physical contact or habitat sharing with them, will have a potential risk. Thus, we estimated and observed their home range, preferred habitats, morphology, behavior, and ecology. Then, comparing with existing knowledge, we assessed risks to the native anurans. We found a home range of 3474.2 ± 5872.5 m2 and identified three types of habitats for IAB. The analyses showed at least 84% of native anurans (frogs and toads) were at moderate to extreme risks, which included all frogs but only 33% of toads. Finally, we recommended immediate actions to conserve the native anurans based on our results. As this study is the first initiative to assess the specific risk level from the invasiveness of L. catesbeianus, it will help the managers to set conservation priorities and strategies.
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- 2022
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10. Complete mitochondrial genome of the river cooter (Pseudemys concinna, Testudines: Emydidae) in Korea
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Jaehong Park, Seungju Cheon, Seung-Min Park, Ha-Cheol Sung, and Dong-Hyun Lee
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pseudemys concinna ,emydidae ,mitochondrial genome ,Genetics ,QH426-470 - Abstract
The complete mitochondrial genome of Pseudemys concinna in Korea was sequenced and characterized. The mitochondrial genome is constituted of 37 genes (13 protein-coding genes, 22 transfer RNA (tRNA) genes, and two ribosomal RNA (rRNA) genes) and a noncoding region. Phylogenetic analysis based on the complete mitochondrial genome showed that P. concinna has closer relationship with Chrysemys picta than Trachemys scripta elegans. This is the first case for complete mitochondrial genome from P. concinna in Korea, which will provide information for biogeographical studies and management plan for invasive species.
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- 2022
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11. Smart toilets for monitoring COVID-19 surges: passive diagnostics and public health
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T. Jessie Ge, Carmel T. Chan, Brian J. Lee, Joseph C. Liao, and Seung-min Park
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Computer applications to medicine. Medical informatics ,R858-859.7 - Abstract
Continued COVID-19 surges have highlighted the need for widespread testing in addition to vaccination for disease containment. SARS-COV-2 RNA can be found in faecal matter, making human stool another potential source for COVID-19 diagnostics. In this commentary, we highlight potential strategies to use a smart toilet platform to passively monitor COVID-19 surges, enabling earlier detection of infected individuals and promoting public health.
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- 2022
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12. Confirmation of the local establishment of alien invasive turtle, Pseudemys peninsularis, in South Korea, using eggshell DNA
- Author
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Seung-Ju Cheon, Md. Mizanur Rahman, Ji-A Lee, Seung-Min Park, Jae-Hong Park, Dong-Hyun Lee, and Ha-Cheol Sung
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Medicine ,Science - Abstract
Alien invasive species are posing conservation challenges worldwide. Pet trade, one of the many ways, is worsening the situation. Especially, pet turtles have been released into nature due to their longer life span and peoples’ religious and traditional beliefs. In addition, unwanted and undesired pets are also released. While information on the successful local establishment and subsequent dispersal into new habitats is required to designate an invasive and ecosystem-disturbing species, alien freshwater turtle nests have always been hard to find and identify in nature. Because one should identify nests by the eggs, which do not always guide properly, as adults abandon the sites quickly. We thought the recent advancement in DNA technology may help improve the situation. We studied Pseudemys peninsularis, one of the most traded freshwater turtle pet species, which has already been reported from a wide range of wild areas in South Korea. Yet, it is not designated as ecosystem-disturbing species due to a lack of adequate information on their local reproduction and establishment. We conducted surveys and found two nests in Jeonpyeongje Neighborhood Park, Maewol-dong, Seo-gu, Gwangju. We developed the methodology for extracting DNA from the eggshells and successfully identified the nests by phylogenetic analysis and verified through egg characteristics and morphological features of artificially hatched juveniles. This was the first successful initiative to extract DNA from freshwater turtle eggshells. We believe it will help future researchers identify the alien invasive turtle nests and develop their control and management policies. In addition, our study also included comparative descriptions and schematic diagrams of the eggs of eight freshwater turtles, including a native and three ecosystem-disturbing species, from South Korea. We urged an immediate designation of P. peninsularis as an ecosystem-disturbing species considering its local establishment, distribution range, and potential negative impact on native ecosystems.
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- 2023
13. Recent Trends in Lateral Flow Immunoassays with Optical Nanoparticles
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Jaehi Kim, Min-Sup Shin, Jonghyun Shin, Hyung-Mo Kim, Xuan-Hung Pham, Seung-min Park, Dong-Eun Kim, Young Jun Kim, and Bong-Hyun Jun
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lateral flow immunoassay ,diagnosis ,nanoparticle ,optical nanoparticles ,Biology (General) ,QH301-705.5 ,Chemistry ,QD1-999 - Abstract
Rapid, accurate, and convenient diagnosis is essential for effective disease management. Various detection methods, such as enzyme-linked immunosorbent assay, have been extensively used, with lateral flow immunoassay (LFIA) recently emerging as a major diagnostic tool. Nanoparticles (NPs) with characteristic optical properties are used as probes for LFIA, and researchers have presented various types of optical NPs with modified optical properties. Herein, we review the literature on LFIA with optical NPs for the detection of specific targets in the context of diagnostics.
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- 2023
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14. Impact Assessment of Beach Erosion from Construction of Artificial Coastal Structures Using Parabolic Bay Shape Equation
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Changbin Lim, Sahong Lee, Seung-Min Park, and Jung Lyul Lee
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longshore sediment ,parabolic equilibrium shoreline ,shoreline deformation ,impact assessment ,coastal structures ,Ocean engineering ,TC1501-1800 - Abstract
Wave field changes resulting from artificial coastal structures constructed in coastal zones have emerged as a major cause of beach erosion, among other factors. The rates of erosion along the eastern coast of Korea have varied mainly owing to the construction of various ports and coastal structures; however, impact assessments of these structures on beach erosion have not been appropriately conducted. Thus, in this study, a methodology to assess the impact of erosion owing to the construction of artificial structures has been proposed, for which a parabolic bay shape equation is used in determining the shoreline angle deformation caused by the structures. Assuming that the conditions of sediment or waves have similar values in most coastal areas, a primary variable impacting coastal sediment transport is the deformation of an equilibrium shoreline relative to the existing beach. Therefore, the angle rotation deforming the equilibrium of a shoreline can be the criterion for evaluating beach erosion incurred through the construction of artificial structures. The evaluation criteria are classified into three levels: safety, caution, and danger. If the angle rotation of the equilibrium shoreline is 0.1° or less, the beach distance was considered to be safe in the present study; however, if this angle is 0.35° or higher, the beach distance is considered to be in a state of danger. Furthermore, in this study, the distance affected by beach erosion is calculated in areas of the eastern coast where artificial structures, mainly including ports and power plants, were constructed; thereafter, an impact assessment of the beach erosion around these areas was conducted. Using a proposed methodology, Gungchon Port was evaluated with caution, whereas Donghae Port, Sokcho Port, and Samcheok LNG were evaluated as being in a state of danger.
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- 2020
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15. Complete mitochondrial genome of the peninsula cooter (Pseudemys peninsularis, Testudines: Emydidae) in Korea
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Dayeon Chung, Jaehong Park, Seungju Cheon, Seung-Min Park, Ha-Cheol Sung, and Dong-Hyun Lee
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pseudemys peninsularis ,emydidae ,mitochondrial genome ,Genetics ,QH426-470 - Abstract
The complete mitochondrial genome of Pseudemys peninsularis in Korea was sequenced and characterized. The mitochondrial genome is constituted of 37 genes (13 protein-coding genes, 22 transfer RNA genes, and two ribosomal RNA genes) and a noncoding region. Phylogenetic analysis based on the 13 protein-coding gene sequences showed that P. peninsularis has closer relationship with Chrysemys picta than Trachemys scripta elegans. This is the first case for a complete mitochondrial genome from P. peninsularis, which will provide information for biogeographical studies and management plans for invasive species.
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- 2022
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16. Synthesis and Applications of Optical Materials
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Seung-Min Park and Bong-Hyun Jun
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n/a ,Chemistry ,QD1-999 - Abstract
As optical materials have shown outstanding physical and chemical characteristics in the bio, medical, electronics, energy and related fields of studies, the potential benefits of using these materials have been widely recognized [...]
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- 2023
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17. Erosion Control Line (ECL) Establishment Using Coastal Erosion Width Prediction Model by High Wave Height
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Seung-Min Park, Seol-Hwa Park, Jung-Lyul Lee, and Tae-Kon Kim
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erosion control line ,mean shore line ,haesabeen ,normal distribution ,median grain size ,Ocean engineering ,TC1501-1800 - Abstract
The average coastline and the erosion control line introduced as the management coastline, and the average shoreline (MSL) was established from the observed coastline. Also, the median grain size and the wave height of 30-years return period were applied. The erosion control line (ECL) was established through the model, HaeSaBeeN. These two lines set the coastline for evaluation. Based on the observed monitoring data along the coastline, the 1-day variation according to the normal distribution was used to estimate the regional variation, and the width of the erosion was calculated by applying the median grain size (D50) and the wave height of 30-years return period through the high-wave coastal erosion width model, i.e., HaeSaBeeN.
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- 2019
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18. Complete mitochondrial genome of the distinct red-eared slider (Trachemys scripta ssp., Testudines: Emydidae) in Korea
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Jaehong Park, Seung-Min Park, Jae-I Moon, Yun-Ju Song, Jae Hyeok Choi, Ha-Cheol Sung, and Dong-Hyun Lee
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trachemys scripta ssp. ,invasive species ,mitochondrial genome ,phylogenetic analysis ,Genetics ,QH426-470 - Abstract
The complete mitochondrial (mt) genome of Trachemys scripta ssp. in Korea was sequenced and characterized. The mt genome is constituted of 37 genes (13 protein-coding genes, 22 transfer RNA genes and 2 ribosomal RNA genes) and a control region. Phylogenetic analysis based on the complete mt genome showed that the unidentified turtle had the mt genome closely related to that of T. s. elegans, though it had distinct morphology compared to T. s. elegans. This study can provide information for biogeographical studies and management plan for invasive species.
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- 2021
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19. Complete mitochondrial genome of the Cumberland slider (Trachemys scripta troostii, Testudienes: Emydidae) in Korea
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Gayeon Ryu, Jae-I Moon, Yun-Ju Song, Jaehong Park, Seung-Min Park, Jae Hyeok Choi, Ha-Cheol Sung, and Dong-Hyun Lee
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trachemys scripta troostii ,mitochondrial genome ,phylogenetic tree ,phylogenetic analysis ,Genetics ,QH426-470 - Abstract
The complete mitochondrial (mt) genome of Trachemys scripta troostii was sequenced and was characterized, which comprised 37 genes (13 protein-coding genes, 22 transfer RNAs, and 2 ribosomal RNAs) and a non-coding control region. Phylogenetic analysis based on the full mt genome indicated that T. s. troostii was more closely related to T. scripta from Canada than to T. s. elegans from China or T. s. scripta fom China. This is the first complete mt genome from T. s. troostii, which provides data for further study of phylogeny in Emydidae.
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- 2021
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20. Highly Bright Silica-Coated InP/ZnS Quantum Dot-Embedded Silica Nanoparticles as Biocompatible Nanoprobes
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Kyeong-Min Ham, Minhee Kim, Sungje Bock, Jaehi Kim, Wooyeon Kim, Heung Su Jung, Jaehyun An, Hobeom Song, Jung-Won Kim, Hyung-Mo Kim, Won-Yeop Rho, Sang Hun Lee, Seung-min Park, Dong-Eun Kim, and Bong-Hyun Jun
- Subjects
quantum dots (QDs) ,silica-coated InP/ZnS QD-embedded silica nanoparticles ,biocompatible nanoprobes ,photoluminescence (PL) ,syngeneic mice ,in vivo ,Biology (General) ,QH301-705.5 ,Chemistry ,QD1-999 - Abstract
Quantum dots (QDs) have outstanding optical properties such as strong fluorescence, excellent photostability, broad absorption spectra, and narrow emission bands, which make them useful for bioimaging. However, cadmium (Cd)-based QDs, which have been widely studied, have potential toxicity problems. Cd-free QDs have also been studied, but their weak photoluminescence (PL) intensity makes their practical use in bioimaging challenging. In this study, Cd-free QD nanoprobes for bioimaging were fabricated by densely embedding multiple indium phosphide/zinc sulfide (InP/ZnS) QDs onto silica templates and coating them with a silica shell. The fabricated silica-coated InP/ZnS QD-embedded silica nanoparticles (SiO2@InP QDs@SiO2 NPs) exhibited hydrophilic properties because of the surface silica shell. The quantum yield (QY), maximum emission peak wavelength, and full-width half-maximum (FWHM) of the final fabricated SiO2@InP QDs@SiO2 NPs were 6.61%, 527.01 nm, and 44.62 nm, respectively. Moreover, the brightness of the particles could be easily controlled by adjusting the amount of InP/ZnS QDs in the SiO2@InP QDs@SiO2 NPs. When SiO2@InP QDs@SiO2 NPs were administered to tumor syngeneic mice, the fluorescence signal was prominently detected in the tumor because of the preferential distribution of the SiO2@InP QDs@SiO2 NPs, demonstrating their applicability in bioimaging with NPs. Thus, SiO2@InP QDs@SiO2 NPs have the potential to successfully replace Cd-based QDs as highly bright and biocompatible fluorescent nanoprobes.
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- 2022
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21. Confirmation of the Applicability of Skeletochronology and Estimating the Age Structure of Kaloula borealis (Microhylidae: Anura) at Lake Sihwa, South Korea
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Md Mizanur Rahman, Yu-Young Lee, Seung-Min Park, Choong-Ho Ham, and Ha-Cheol Sung
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life history trait ,growth curve ,lines of arrested growth ,innermost visible line ,sexual size dimorphism ,Biology (General) ,QH301-705.5 - Abstract
Despite having some limitations, the use of skeletochronology—age determination by counting lines of arrested growth (LAGs)—in amphibians is increasing. The main limitation of using skeletochronology is identifying the innermost visible line (IVL) and counting the exact number of LAGs. Thus, we tested its applicability to Kaloula borealis, a class II endangered amphibian in South Korea. We reared juveniles in the lab to investigate the process of bone formation. This confirmed the development of one LAG each year. Hence, our study validates skeletochronology for the age determination of this species and recommends it for others that show similar growth patterns. Furthermore, the comparison of threshold diameters with the IVL of wild individuals confirmed no LAG1 resorption. The average age of males and females in this population was 2.75 ± 1.05 and 3.64 ± 3 years, respectively. We estimated sexual maturity at 2 years with rapid growth up to that stage in both sexes. We found a female-dominated sexual size dimorphism. This study offers accurate information on the life history traits and age structure of K. borealis that may help to evaluate population dynamics in other areas, identify vulnerable life stages and sites, assess the causes of population decline, and set conservation priorities.
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- 2022
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22. Lateral Flow Immunoassay with Quantum-Dot-Embedded Silica Nanoparticles for Prostate-Specific Antigen Detection
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Sungje Bock, Hyung-Mo Kim, Jaehi Kim, Jaehyun An, Yun-Sik Choi, Xuan-Hung Pham, Ahla Jo, Kyeong-min Ham, Hobeom Song, Jung-Won Kim, Eunil Hahm, Won-Yeop Rho, Sang Hun Lee, Seung-min Park, Sangchul Lee, Dae Hong Jeong, Ho-Young Lee, and Bong-Hyun Jun
- Subjects
prostate-specific antigen ,prostate cancer ,lateral flow immunoassay ,quantum dot ,quantum-dot-embedded silica nanoparticles ,Chemistry ,QD1-999 - Abstract
Prostate cancer can be detected early by testing the presence of prostate-specific antigen (PSA) in the blood. Lateral flow immunoassay (LFIA) has been used because it is cost effective and easy to use and also has a rapid sample-to-answer process. Quantum dots (QDs) with very bright fluorescence have been previously used to improve the detection sensitivity of LFIAs. In the current study, a highly sensitive LFIA kit was devised using QD-embedded silica nanoparticles. In the present study, only a smartphone and a computer software program, ImageJ, were used, because the developed system had high sensitivity by using very bright nanoprobes. The limit of PSA detection of the developed LFIA system was 0.138 ng/mL. The area under the curve of this system was calculated as 0.852. The system did not show any false-negative result when 47 human serum samples were analyzed; it only detected PSA and did not detect alpha-fetoprotein and newborn calf serum in the samples. Additionally, fluorescence was maintained on the strip for 10 d after the test. With its high sensitivity and convenience, the devised LFIA kit can be used for the diagnosis of prostate cancer.
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- 2021
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23. Complete mitochondrial genome of the red-eared slider (Trachemys scripta elegans, Testudines: Emydidae) in Korea
- Author
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Jaehong Park, Jae-I Moon, Yun-Ju Song, Seung-Min Park, Seungju Cheon, Ha-Cheol Sung, and Dong-Hyun Lee
- Subjects
trachemys scripta elegans ,emydidae ,mitochondrial genome ,Genetics ,QH426-470 - Abstract
The complete mitochondrial (mt) genome of Trachemys scripta elegans in Korea was sequenced and characterized. The mt genome is constituted of 37 genes (13 protein-coding genes, 22 transfer RNA genes and 2 ribosomal RNA genes) and a noncoding control region. Phylogenetic analysis based on the complete mt genome showed that T. s. elegans Korea has closer relationship with T. scripta Canada than T. s. elegans China. This is the first complete mt genome from T. s. elegans in Korea, which provides information for biogeographical studies and management plan for invasive species.
- Published
- 2021
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24. Synthesis and Application of Silica-Coated Quantum Dots in Biomedicine
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Xuan-Hung Pham, Seung-Min Park, Kyeong-Min Ham, San Kyeong, Byung Sung Son, Jaehi Kim, Eunil Hahm, Yoon-Hee Kim, Sungje Bock, Wooyeon Kim, Seunho Jung, Sangtaek Oh, Sang Hun Lee, Do Won Hwang, and Bong-Hyun Jun
- Subjects
quantum dot (QD) ,surface modification ,silica coating ,silica encapsulation ,bioapplication ,Biology (General) ,QH301-705.5 ,Chemistry ,QD1-999 - Abstract
Quantum dots (QDs) are semiconductor nanoparticles with outstanding optoelectronic properties. More specifically, QDs are highly bright and exhibit wide absorption spectra, narrow light bands, and excellent photovoltaic stability, which make them useful in bioscience and medicine, particularly for sensing, optical imaging, cell separation, and diagnosis. In general, QDs are stabilized using a hydrophobic ligand during synthesis, and thus their hydrophobic surfaces must undergo hydrophilic modification if the QDs are to be used in bioapplications. Silica-coating is one of the most effective methods for overcoming the disadvantages of QDs, owing to silica’s physicochemical stability, nontoxicity, and excellent bioavailability. This review highlights recent progress in the design, preparation, and application of silica-coated QDs and presents an overview of the major challenges and prospects of their application.
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- 2021
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25. Silver-Assembled Silica Nanoparticles in Lateral Flow Immunoassay for Visual Inspection of Prostate-Specific Antigen
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Hyung-Mo Kim, Jaehi Kim, Sungje Bock, Jaehyun An, Yun-Sik Choi, Xuan-Hung Pham, Myeong Geun Cha, Bomi Seong, Wooyeon Kim, Yoon-Hee Kim, Hobeom Song, Jung-Won Kim, Seung-min Park, Sang Hun Lee, Won-Yeop Rho, Sangchul Lee, Dae Hong Jeong, Ho-Young Lee, and Bong-Hyun Jun
- Subjects
silica nanoparticles ,prostate-specific antigen ,lateral flow immunoassay ,Chemical technology ,TP1-1185 - Abstract
Prostate-specific antigen (PSA) is the best-known biomarker for early diagnosis of prostate cancer. For prostate cancer in particular, the threshold level of PSA 2@Ag@SiO2 NPs) that were applied to a visual lateral flow immunoassay (LFIA) platform for PSA detection. During synthesis, the ratio of silica NPs to silver nitrate changed, and as the synthesized NPs exhibited distinct UV spectra and colors, most optimized SiO2@Ag@SiO2 NPs showed the potential for early prostate cancer diagnosis. The PSA detection limit of our LFIA platform was 1.1 ng/mL. By applying each SiO2@Ag@SiO2 NP to the visual LFIA platform, optimized SiO2@Ag@SiO2 NPs were selected in the test strip, and clinical samples from prostate cancer patients were successfully detected as the boundaries of non-specific binding were clearly seen and the level of PSA was
- Published
- 2021
- Full Text
- View/download PDF
26. Recent Advances in Surface-Enhanced Raman Scattering Magnetic Plasmonic Particles for Bioapplications
- Author
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Kim-Hung Huynh, Eunil Hahm, Mi Suk Noh, Jong-Hwan Lee, Xuan-Hung Pham, Sang Hun Lee, Jaehi Kim, Won-Yeop Rho, Hyejin Chang, Dong Min Kim, Ahruem Baek, Dong-Eun Kim, Dae Hong Jeong, Seung-min Park, and Bong-Hyun Jun
- Subjects
Surface-Enhanced Raman Scattering (SERS) ,magnetic nanoparticles ,plasmonic nanoparticles ,detection ,drug delivery ,cancer therapy ,Chemistry ,QD1-999 - Abstract
The surface-enhanced Raman scattering (SERS) technique, that uses magnetic plasmonic particles (MPPs), is an advanced SERS detection platform owing to the synergetic effects of the particles’ magnetic and plasmonic properties. As well as being an ultrasensitive and reliable SERS material, MPPs perform various functions, such as aiding in separation, drug delivery, and acting as a therapeutic material. This literature discusses the structure and multifunctionality of MPPs, which has enabled the novel application of MPPs to various biological fields.
- Published
- 2021
- Full Text
- View/download PDF
27. Hybrid CuxO–TiO2 Heterostructured Composites for Photocatalytic CO2 Reduction into Methane Using Solar Irradiation: Sunlight into Fuel
- Author
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Seung-Min Park, Abdul Razzaq, Young Ho Park, Saurav Sorcar, Yiseul Park, Craig A. Grimes, and Su-Il In
- Subjects
Chemistry ,QD1-999 - Published
- 2016
- Full Text
- View/download PDF
28. Metal Nano/Microparticles for Bioapplications
- Author
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Xuan-Hung Pham, Seung-min Park, and Bong-Hyun Jun
- Subjects
n/a ,Biology (General) ,QH301-705.5 ,Chemistry ,QD1-999 - Abstract
Nano/micro particles are considered to be the most valuable and important functional materials in the field of materials science and engineering [...]
- Published
- 2021
- Full Text
- View/download PDF
29. High-Density Lipoprotein Nanoparticle Imaging in Atherosclerotic Vascular Disease
- Author
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Nicholas J. Leeper, MD, Seung-min Park, PhD, and Bryan Ronain Smith, PhD
- Subjects
Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Summary: Nanoparticles promise to advance the field of cardiovascular theranostics. However, their sustained and targeted delivery remains an important obstacle. The body synthesizes some ânaturalâ nanoparticles, including high-density lipoprotein (HDL), which may home to the atherosclerotic plaque and promote cholesterol efflux. In a recent article published in JACC: Cardiovascular Imaging, investigators generated modified, radiolabeled HDL nanoparticles and confirmed they accumulated in atherosclerotic lesions from several different species. These approaches hold promise for the noninvasive diagnosis of vulnerable plaque and in the stratification of patients in whom HDL-mimetic therapy may have a clinical benefit. Key Words: atherosclerosis, HDL, imaging, nanoparticles, macrophages/monocytes
- Published
- 2017
- Full Text
- View/download PDF
30. Advanced Parameter-Setting-Free Harmony Search Algorithm
- Author
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Yong-Woon Jeong, Seung-Min Park, Zong Woo Geem, and Kwee-Bo Sim
- Subjects
metaheuristic ,harmony search ,parameter setting free ,Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Biology (General) ,QH301-705.5 ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
In this paper, we propose an advanced parameter-setting-free (PSF) scheme to solve the problem of setting the parameters for the harmony search (HS) algorithm. The use of the advanced PSF method solves the problems of the conventional PSF scheme that results from a large number of iterations and shows good results compared to fixing the parameters required for the HS algorithm. In addition, unlike the conventional PSF method, the advanced PSF method does not use additional memory. We expect the advanced PSF method to be applicable to various fields that use the HS algorithm because it reduces the memory utilization for operations while obtaining better results than conventional PSF schemes.
- Published
- 2020
- Full Text
- View/download PDF
31. Multigene profiling of single circulating tumor cells
- Author
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Seung-min Park, Dawson J. Wong, Chin Chun Ooi, Jared C. Nesvet, Viswam S. Nair, Shan X. Wang, and Sanjiv S. Gambhir
- Subjects
circulating tumor cells ,rare-cell sorting ,single-cell analysis ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Numerous techniques for isolating circulating tumor cells (CTCs) have been developed. Concurrently, single-cell techniques that can reveal molecular components of CTCs have become widely available. We discuss how the combination of isolation and multigene profiling of single CTCs in our platform can facilitate eventual translation to the clinic.
- Published
- 2017
- Full Text
- View/download PDF
32. High-throughput full-length single-cell mRNA-seq of rare cells.
- Author
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Chin Chun Ooi, Gary L Mantalas, Winston Koh, Norma F Neff, Teruaki Fuchigami, Dawson J Wong, Robert J Wilson, Seung-Min Park, Sanjiv S Gambhir, Stephen R Quake, and Shan X Wang
- Subjects
Medicine ,Science - Abstract
Single-cell characterization techniques, such as mRNA-seq, have been applied to a diverse range of applications in cancer biology, yielding great insight into mechanisms leading to therapy resistance and tumor clonality. While single-cell techniques can yield a wealth of information, a common bottleneck is the lack of throughput, with many current processing methods being limited to the analysis of small volumes of single cell suspensions with cell densities on the order of 107 per mL. In this work, we present a high-throughput full-length mRNA-seq protocol incorporating a magnetic sifter and magnetic nanoparticle-antibody conjugates for rare cell enrichment, and Smart-seq2 chemistry for sequencing. We evaluate the efficiency and quality of this protocol with a simulated circulating tumor cell system, whereby non-small-cell lung cancer cell lines (NCI-H1650 and NCI-H1975) are spiked into whole blood, before being enriched for single-cell mRNA-seq by EpCAM-functionalized magnetic nanoparticles and the magnetic sifter. We obtain high efficiency (> 90%) capture and release of these simulated rare cells via the magnetic sifter, with reproducible transcriptome data. In addition, while mRNA-seq data is typically only used for gene expression analysis of transcriptomic data, we demonstrate the use of full-length mRNA-seq chemistries like Smart-seq2 to facilitate variant analysis of expressed genes. This enables the use of mRNA-seq data for differentiating cells in a heterogeneous population by both their phenotypic and variant profile. In a simulated heterogeneous mixture of circulating tumor cells in whole blood, we utilize this high-throughput protocol to differentiate these heterogeneous cells by both their phenotype (lung cancer versus white blood cells), and mutational profile (H1650 versus H1975 cells), in a single sequencing run. This high-throughput method can help facilitate single-cell analysis of rare cell populations, such as circulating tumor or endothelial cells, with demonstrably high-quality transcriptomic data.
- Published
- 2017
- Full Text
- View/download PDF
33. Pref-1 Marks Very Early Mesenchymal Precursors Required for Adipose Tissue Development and Expansion
- Author
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Carolyn S. Hudak, Olga Gulyaeva, Yuhui Wang, Seung-min Park, Luke Lee, Chulho Kang, and Hei Sook Sul
- Subjects
Biology (General) ,QH301-705.5 - Abstract
Pref-1 is an EGF-repeat-containing protein that inhibits adipocyte differentiation. To better understand the origin and development of white adipose tissue (WAT), we generated transgenic mouse models for transient or permanent fluorescent labeling of cells using the Pref-1 promoter, facilitating inducible ablation. We show that Pref-1-marked cells retain proliferative capacity and are very early adipose precursors, prior to expression of Zfp423 or PPARγ. In addition, the Pref-1-marked cells establish that adipose precursors are mesenchymal, but not endothelial or pericytal, in origin. During embryogenesis, Pref-1-marked cells first appear in the dorsal mesenteric region as early as embryonic day 10.5 (E10.5). These cells become lipid-laden adipocytes at E17.5 in the subcutaneous region, whereas visceral WAT develops after birth. Finally, ablation of Pref-1-marked cells prevents not only embryonic WAT development but also later adult adipose expansion upon high-fat feeding, demonstrating the requirement of Pref-1 cells for adipogenesis.
- Published
- 2014
- Full Text
- View/download PDF
34. Influence of Hydraulic Pressure on Performance Deterioration of Direct Contact Membrane Distillation (DCMD) Process
- Author
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Seung-Min Park and Sangho Lee
- Subjects
direct contact membrane distillation (DCMD), hydrophobic membrane ,hydraulic pressure ,compaction ,membrane structure ,wetting ,Chemical technology ,TP1-1185 ,Chemical engineering ,TP155-156 - Abstract
Direct contact membrane distillation (DCMD) is a membrane distillation (MD) configuration where feed and distillate directly contact with a hydrophobic membrane. Depending on its operating conditions, the hydraulic pressures of the feed and distillate may be different, leading to adverse effects on the performance of the DCMD process. Nevertheless, little information is available on how hydraulic pressure affects the efficiency of DCMD. Accordingly, this paper investigates the effect of external hydraulic pressure on the process efficiency of DCMD. Gas permeabilities of MD membranes were measured to analyze the effect of membrane compaction by external pressure. Mass transfer coefficients were calculated using experimental data to quantitatively explain the pressure effect. Experiments were also carried out using a laboratory-scale DCMD set-up. After applying the pressure, the cross-sections and surfaces of the membranes were examined using a scanning electron microscope (SEM). Results showed that the membrane structural parameters such as porosity and thickness were changed under relatively high pressure conditions (>30 kPa), leading to reduction in flux. The mass transfer coefficients were also significantly influenced by the hydraulic pressure. Moreover, local wetting of the membranes were observed even below the liquid entry pressure (LEP), which decreased the rejection of salts. These results suggest that the control of hydraulic pressure is important for efficient operation of DCMD process.
- Published
- 2019
- Full Text
- View/download PDF
35. Electroencephalography Signal Grouping and Feature Classification Using Harmony Search for BCI
- Author
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Tae-Ju Lee, Seung-Min Park, and Kwee-Bo Sim
- Subjects
Mathematics ,QA1-939 - Abstract
This paper presents a heuristic method for electroencephalography (EEG) grouping and feature classification using harmony search (HS) for improving the accuracy of the brain-computer interface (BCI) system. EEG, a noninvasive BCI method, uses many electrodes on the scalp, and a large number of electrodes make the resulting analysis difficult. In addition, traditional EEG analysis cannot handle multiple stimuli. On the other hand, the classification method using the EEG signal has a low accuracy. To solve these problems, we use a heuristic approach to reduce the complexities in multichannel problems and classification. In this study, we build a group of stimuli using the HS algorithm. Then, the features from common spatial patterns are classified by the HS classifier. To confirm the proposed method, we perform experiments using 64-channel EEG equipment. The subjects are subjected to three kinds of stimuli: audio, visual, and motion. Each stimulus is applied alone or in combination with the others. The acquired signals are processed by the proposed method. The classification results in an accuracy of approximately 63%. We conclude that the heuristic approach using the HS algorithm on the BCI is beneficial for EEG signal analysis.
- Published
- 2013
- Full Text
- View/download PDF
36. Biological research and self-driving labs in deep space supported by artificial intelligence.
- Author
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Lauren M. Sanders, Ryan T. Scott, Jason H. Yang, Amina Ann Qutub, Héctor García Martín, Daniel C. Berrios, Jaden J. A. Hastings, Jon Rask, Graham Mackintosh, Adrienne L. Hoarfrost, Stuart J. Chalk, John Kalantari, Kia Khezeli, Erik L. Antonsen, Joel Babdor, Richard Barker, Sergio E. Baranzini, Afshin Beheshti, Guillermo M. Delgado-Aparicio, Benjamin S. Glicksberg, Casey S. Greene, Melissa A. Haendel, Arif A. Hamid, Philip Heller, Daniel Jamieson, Katelyn J. Jarvis, Svetlana V. Komarova, Matthieu Komorowski, Prachi Kothiyal, Ashish Mahabal, Uri Manor, Christopher E. Mason, Mona Matar, George I. Mias, Jack Miller, Jerry G. Myers Jr., Charlotte A. Nelson, Jonathan Oribello, Seung-Min Park, Patricia Parsons-Wingerter, R. K. Prabhu, Robert J. Reynolds, Amanda Saravia-Butler, Suchi Saria, Aenor Sawyer, Nitin Kumar Singh 0001, Michael Snyder 0001, Frank Soboczenski, Karthik Soman, Corey A. Theriot, David Van Valen, Kasthuri Venkateswaran, Liz Warren, Liz Worthey, Marinka Zitnik, and Sylvain V. Costes
- Published
- 2023
- Full Text
- View/download PDF
37. Biomonitoring and precision health in deep space supported by artificial intelligence.
- Author
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Ryan T. Scott, Lauren M. Sanders, Erik L. Antonsen, Jaden J. A. Hastings, Seung-Min Park, Graham Mackintosh, Robert J. Reynolds, Adrienne L. Hoarfrost, Aenor Sawyer, Casey S. Greene, Benjamin S. Glicksberg, Corey A. Theriot, Daniel C. Berrios, Jack Miller, Joel Babdor, Richard Barker, Sergio E. Baranzini, Afshin Beheshti, Stuart J. Chalk, Guillermo M. Delgado-Aparicio, Melissa A. Haendel, Arif A. Hamid, Philip Heller, Daniel Jamieson, Katelyn J. Jarvis, John Kalantari, Kia Khezeli, Svetlana V. Komarova, Matthieu Komorowski, Prachi Kothiyal, Ashish Mahabal, Uri Manor, Héctor García Martín, Christopher E. Mason, Mona Matar, George I. Mias, Jerry G. Myers Jr., Charlotte A. Nelson, Jonathan Oribello, Patricia Parsons-Wingerter, R. K. Prabhu, Amina Ann Qutub, Jon Rask, Amanda Saravia-Butler, Suchi Saria, Nitin Kumar Singh 0001, Michael Snyder 0001, Frank Soboczenski, Karthik Soman, David Van Valen, Kasthuri Venkateswaran, Liz Warren, Liz Worthey, Jason H. Yang, Marinka Zitnik, and Sylvain V. Costes
- Published
- 2023
- Full Text
- View/download PDF
38. The Mediating Effect of Spiritual Coping on the Relationship between Positive Cognitive Emotion Regulation and Post-Traumatic Growth of Christians who have Experienced Trauma
- Author
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Ha Im Ryu and Seung Min Park
- Subjects
Cultural Studies ,Economics and Econometrics ,Organizational Behavior and Human Resource Management ,History ,Literature and Literary Theory ,Strategy and Management ,Geography, Planning and Development ,General Chemistry ,Development ,Condensed Matter Physics ,Education ,Accounting ,Management of Technology and Innovation ,Anthropology ,Political Science and International Relations ,General Materials Science ,Finance ,General Psychology - Published
- 2023
39. Visual Speech Recognition of Korean Words Using Convolutional Neural Network.
- Author
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Sung-Won Lee, Je-Hun Yu, Seung-Min Park 0002, and Kwee-Bo Sim
- Published
- 2019
- Full Text
- View/download PDF
40. The impact of body mass index on abdominal injuries in motorcycle crashes in South Korea.
- Author
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Yonghun Gwak, Dae Kon Kim, Joo Jeong, You Hwan Jo, Dong Keon Lee, Seung Min Park, Yeongho Choi, and Yu Jin Kim
- Subjects
ABDOMINAL injuries ,MOTORCYCLING injuries ,HELMETS ,BODY mass index ,LOGISTIC regression analysis ,AUTOMOBILE occupants - Abstract
Objective: Motorcyclists face a higher risk of severe morbidity and mortality compared to automobile passengers. This study aimed to determine the injury characteristics of motorcyclists according to their body mass index (BMI). Methods: A retrospective observational cross-sectional study was conducted using data from the Emergency Department-based Injury In-depth Surveillance (EDIIS) registry. Motorcycle riders aged 18 or older who were injured and admitted to study hospitals between 2019 and 2020 were included. Patients were divided into three groups based on BMI cutoffs of 18.5 and 25 kg/m²: the low, optimal, and high BMI groups. The primary outcome was anatomical injury location according to the abbreviated injury scale. The secondary outcomes were the surgery and intensive care unit admission rate, and the 48-h and 30-day in-hospital mortality. Multivariable logistic regression analysis was performed to assess the impact of BMI on outcomes. Results: Among 1280 patients, the low and high BMI groups had higher risk of abdominal injuries (AIS ≥ 2) than the optimal BMI group, with adjusted odds ratios of 2.82 (95% CI 1.41-5.63) and 1.61 (95% CI 1.17-2.21), respectively. Only the low BMI group had a significant association with severe abdominal injury (AIS ≥ 3), with an adjusted odds ratio of 3.11 (95% CI 1.31-7.39). No significant association was found between BMI and surgery, ICU admission, or mortality. Conclusion: The low BMI group was more likely to have an abdominal injury (AIS score ≥2 or AIS score ≥3) during motorcycle injuries. BMI was not associated with surgery, ICU admission, or mortality. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
41. The Magnitude of Change in Serum Phosphate Concentration Is Associated with Mortality in Patients with Severe Trauma.
- Author
-
Changwoo Im, Dong-Hyun Jang, Woo Jin Jung, Seung Min Park, and Dong Keon Lee
- Abstract
Purpose: Previous studies have suggested that serum phosphate concentration is a prognostic factor in critically ill patients. However, the association between changes in serum phosphate levels and prognosis of patients with trauma remains unclear. Materials and Methods: This study included patients with severe trauma who were treated at the emergency department. Delta phosphate (Δ phosphate) was defined as the difference between serum phosphate concentrations measured at baseline and after 24 hours from the initial measurement. Patients were divided into five groups according to their Δ phosphate levels: group I (Δ phosphate <-2 mg/dL), group II (Δ phosphate -2 to -0.5 mg/dL), group III (Δ phosphate -0.5 to 0.5 mg/dL), group IV (Δ phosphate 0.5 to 2 mg/dL), and group V (Δ phosphate ≥2 mg/dL). Results: Overall, 1905 patients with severe trauma were included in the analysis. The 30-day mortality was the lowest in group III and tended to increase in groups with a larger Δ phosphate in both the positive and negative directions (group I: 13.7%, group II: 6.8%, group III: 4.6%, group IV: 6.6%, and group V: 26.8%). In multivariable analysis with group III as the reference group, the odds ratios (ORs) of mortality were statistically significant in group IV [OR, 1.92; 95% confidence interval (CI), 1.05-3.56] and group V (OR, 5.28; 95% CI, 2.47-11.24). Conclusion: An increase in serum phosphate concentrations 24 hours after the initial measurement could be considered as an independent prognostic factor in patients with severe trauma. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
42. Enhancement mechanism of quantum yield in core/shell/shell quantum dots of ZnS-AgIn5S8/ZnIn2S4/ZnS.
- Author
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Seonghyun Jeong, Minji Ko, Sangwon Nam, Jun Hwan Oh, Seung Min Park, Young Rag Do, and Jae Kyu Song
- Published
- 2024
- Full Text
- View/download PDF
43. Beyond Low Earth Orbit: Biomonitoring, Artificial Intelligence, and Precision Space Health.
- Author
-
Ryan T. Scott, Erik L. Antonsen, Lauren M. Sanders, Jaden J. A. Hastings, Seung-Min Park, Graham Mackintosh, Robert J. Reynolds, Adrienne L. Hoarfrost, Aenor Sawyer, Casey S. Greene, Benjamin S. Glicksberg, Corey A. Theriot, Daniel C. Berrios, Jack Miller, Joel Babdor, Richard Barker, Sergio E. Baranzini, Afshin Beheshti, Stuart J. Chalk, Guillermo M. Delgado-Aparicio, Melissa A. Haendel, Arif A. Hamid, Philip Heller, Daniel Jamieson, Katelyn J. Jarvis, John Kalantari, Kia Khezeli, Svetlana V. Komarova, Matthieu Komorowski, Prachi Kothiyal, Ashish Mahabal, Uri Manor, Héctor García Martín, Christopher E. Mason, Mona Matar, George I. Mias, Jerry G. Myers Jr., Charlotte A. Nelson, Jonathan Oribello, Patricia Parsons-Wingerter, R. K. Prabhu, Amina Ann Qutub, Jon Rask, Amanda Saravia-Butler, Suchi Saria, Nitin Kumar Singh 0001, Frank Soboczenski, Michael Snyder 0001, Karthik Soman, David Van Valen, Kasthuri Venkateswaran, Liz Warren, Liz Worthey, Jason H. Yang, Marinka Zitnik, and Sylvain V. Costes
- Published
- 2021
44. Beyond Low Earth Orbit: Biological Research, Artificial Intelligence, and Self-Driving Labs.
- Author
-
Lauren M. Sanders, Jason H. Yang, Ryan T. Scott, Amina Ann Qutub, Héctor García Martín, Daniel C. Berrios, Jaden J. A. Hastings, Jon Rask, Graham Mackintosh, Adrienne L. Hoarfrost, Stuart J. Chalk, John Kalantari, Kia Khezeli, Erik L. Antonsen, Joel Babdor, Richard Barker, Sergio E. Baranzini, Afshin Beheshti, Guillermo M. Delgado-Aparicio, Benjamin S. Glicksberg, Casey S. Greene, Melissa A. Haendel, Arif A. Hamid, Philip Heller, Daniel Jamieson, Katelyn J. Jarvis, Svetlana V. Komarova, Matthieu Komorowski, Prachi Kothiyal, Ashish Mahabal, Uri Manor, Christopher E. Mason, Mona Matar, George I. Mias, Jack Miller, Jerry G. Myers Jr., Charlotte A. Nelson, Jonathan Oribello, Seung-Min Park, Patricia Parsons-Wingerter, R. K. Prabhu, Robert J. Reynolds, Amanda Saravia-Butler, Suchi Saria, Aenor Sawyer, Nitin Kumar Singh 0001, Frank Soboczenski, Michael Snyder 0001, Karthik Soman, Corey A. Theriot, David Van Valen, Kasthuri Venkateswaran, Liz Warren, Liz Worthey, Marinka Zitnik, and Sylvain V. Costes
- Published
- 2021
45. A Study on the Career Adaptation Experience of General High School Students Enrolled in Vocational Training Courses
- Author
-
Jeehyang Woo and Seung Min Park
- Published
- 2023
46. Lower limb muscle matters in patients with hypoxic brain injury following out-of-hospital cardiac arrest
- Author
-
Dong-Hyun Jang, Seung Min Park, Dong Keon Lee, Dong Won Kim, Chang Woo Im, You Hwan Jo, and Kui Ja Lee
- Subjects
Critical Care and Intensive Care Medicine ,Critical Care Nursing - Abstract
Background: There are conflicting results regarding the association between body mass index and the prognosis of cardiac arrest patients. We investigated the association of the composition and distribution of muscle and fat with neurologic outcomes at hospital discharge in successfully resuscitated out-of-hospital cardiac arrest (OHCA) patients.Methods: This prospective, single-centre, observational study involved adult OHCA patients, conducted between April 2019 and June 2021. The ratio of total skeletal muscle, upper limb muscle, lower limb muscle, and total fat to body weight was measured using InBody S10, a bioimpedance analyser, after achieving the return of spontaneous circulation. Restricted cubic spline curves with four knots were used to examine the relationship between total skeletal muscle, upper limb muscle, and lower limb muscle relative to total body weight and neurologic outcome at discharge. Multivariable logistic regression analysis was performed to assess an independent association.Results: A total of 66 patients were enrolled in the study. The proportion of total muscle and lower limb muscle positively correlated with the possibility of having a good neurologic outcome. The proportion of lower limb muscle showed an independent association in the multivariable analysis (adjusted odds ratio, 2.29; 95% confidence interval, 1.06–13.98), and its optimal cut-off value calculated through receiver operating characteristic curve analysis was 23.1%, which can predict a good neurological outcome. Conclusions: A higher proportion of lower limb muscle to body weight was independently associated with the probability of having a good neurologic outcome in OHCA patients.
- Published
- 2023
47. Interpolation and extrapolation between the magnetic chiral states using autoencoder.
- Author
-
Han Gyu Yoon, Chanki Lee, Doo Bong Lee, Seung Min Park, Jun Woo Choi, Hee Young Kwon, and Changyeon Won
- Published
- 2022
- Full Text
- View/download PDF
48. InP/ZnSeS/ZnS Quantum Dots with High Quantum Yield and Color Purity for Display Devices
- Author
-
Hyeong Seop Shim, Minji Ko, Sangwon Nam, Jun Hwan Oh, Seonghyun Jeong, Yoonji Yang, Seung Min Park, Young Rag Do, and Jae Kyu Song
- Subjects
General Materials Science - Published
- 2023
49. A Study on Geo-morphological Analysis and Risk Assessment Method Using Geospatial Information
- Author
-
Byung Ju Kim, Seon Jung Park, Il Hoon Choi, Seol Hwa Park, Seung Min Park, and Heui Jung Seo
- Abstract
Rock platforms and TTP (breakwater) are dangerous environments commonly subject to tidal and high wave energy on the open coast. This paper is a study on risk assessment to provide risk information, which is a representative method for preventing coastal safety accidents. Risk assessment based on geo-morphological information was conducted for the Halmi-Halabi rock platform in Anmyeon-eup, Taean-gun, Chungcheongnam-do. As a result of the risk assessment in 16 directions, the risk was evaluated high in the NE, ENE, S, SSW, and W directions, where there are many sections with slopes exceeding ±20o, and the NW direction was the lowest. Geo-morphology on rock platform is central to understanding what makes one stretch of complex coastline more hazardous than another, and it can be used to create site-specific morphological risk item. In particular, it will be assisting coastal managers in an effort to reduce the number of injuries and drowning incidents by providing hazard information to assess the relative risk.
- Published
- 2022
50. Risk Assessment of the Accident Place Types Considering the Coastal Activity Time
- Author
-
Heui Jung Seo, Seon Jung Park, Seol Hwa Park, and Seung Min Park
- Abstract
The Korea Coast Guard evaluates the risk of major coastal activity places to prevent coastal accidents, and patrols and manages them based on that, but it is not responding properly to the continuously increasing number of coastal accidents. The reason for this is that, despite the gradual expansion of coastal activity places, there is a lack of manpower to manage and supervise them, resulting in blind spots in coastal accident safety management. Therefore, in order to solve this problem, it is necessary to prepare more efficient and effective measures that check and supplement the current coastal safety management system. Coastal accidents show different characteristics of accident causes and places due to differences in the activity characteristics of users according to time. As a result of analyzing coastal accident data (2017~2021), the frequency of daytime accidents is high in the case of sea rock, beach, and offshore, where family leisure activities are frequent. In the case of wharf, tidal flat and bridge, where accidents due to drinking, disorientation, and suicide mainly occur, the frequency of accidents at night is high. In addition, there were more accidents on weekends when the number of users increased compared to weekdays. This trend indicates that the user's temporal activity characteristics must be reflected in the risk assessment of coastal activity places. Therefore, in this study, based on the case of coastal accidents, the characteristics of accidents at coastal activity places according to time were identified, and the criteria were presented for risk evaluation by grading them. It is expected that it will be possible to lay the foundation for reducing coastal accidents by efficiently managing and supervising coastal activity places over time using the presented evaluation criteria.
- Published
- 2022
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