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12. 36th International Congress of the European Association of Poisons Centres and Clinical Toxicologists (EAPCCT) 24-27 May, 2016, Madrid, Spain

Author

Settimi, L, Giordano, Felice, Celentano, A, Lauria, L, Sesana, F, and Davanzo, F.

Subjects
business.industry, Regeneration (biology), Snap, General Medicine, Pharmacology, Toxicology, Acetylcysteine, 03 medical and health sciences, Regimen, 0302 clinical medicine, medicine.anatomical_structure, Hepatic glutathione, Hepatocyte, medicine, 030212 general & internal medicine, business, 030217 neurology & neurosurgery, medicine.drug
Published
2016

13. Establishing reference values for central blood pressure and its amplification in a general healthy population and according to cardiovascular risk factors

Author

Herbert A., Cruickshank J.K., Laurent S., Boutouyrie P., Shimada K., Kario K., Miyashita H., Eguchi K., Kohara K., Tabara Y., Imai Y., Ito S., Hashimoto J., Uchiba K., Suzuki H., Takenaka T., Takazawa K., Kino M., Yamashina A., Tomiyama H., Dohi Y., Takase H., Jouven X., Empana J.P., Pannier B., Thomas F., Prescott E., Janner J., McEniery C., Cockcroft J., Wilkinson I., Roman M.J., Devereux R.B., Teal V., Townsend R., Vermeersch S., Rietzschel E.R., Van Bortel L., De Buyzere M.L., Segers P., Gillebert T.C., Wang J.-G., Li Y., Lazar J., Salciccioli L., Cunha P., Oliveira P., Cotter J., Vila I., Sousa N., Chirinos J., Medina-Lezama J., Weber T., Rammer M., O'Rourke M.F., Bernd E., Lassnig E., Porodko M., Ammer M., Wassertheurer S., Adji A., Rosenkranz S., Punzengruber C., Kvas E., Dufouil C., Tzourio C., Nijpels G., Dekker J.M., Stehouwer C.D.A., Ferreira I., Twisk J.W., Smulders Y.M., Van De Laar R.J., Van Kallen C.J., Van Greevenbroek M.M., Schalkwijk C.G., Vlachopoulos C., Aznaouridis C., Terentes-Printzios D., Xaplanteris P., Stefanadis C., Schutte A.E., Fourie C.M.T., Van Rooyen J.M., Mahmud A., Feely J., Ghiadoni L., Stea F., Bruno R.M., Cartoni G., Armenia S., Taddei S., Seidlerova J., Vanek J., Filipovsky J., Mayer O., Jr., Lind L., Soveri I., Fellström B., Zilmer M., Cavallini M.C., Pini R., Di Bari M., Marchionni N., Masotti G., Schillaci G., Pucci G., Battista F., Settimi L., Crilly M.A., Kumar V., Clark H.J., Scott N.W., Macdonald A.G., Williams D.J., Hillis G.S., Lee A.J., De Vries A., Small G.R., Zanchetti A., Bilo G., Taurino C., McClure J.D., Schneider M.P., Kawecka-Jaszcz K., Stolarz-Skrzypek K., Klima L., Staessen J.A., Kuznetsova T., Redon J., Martinez F., Rosei E.A., Melander O., Zannad F., Rossignol P., Collin C., Lonati L., Dominiczak A.F., O'Rourke M., Petrak O., Štrauch B., Rosa J., Widimsky J., Pipingas A., Pase M.P., Grima N.A., Stough C., Harris E., Sellick L., Macpherson H., Pascualab J.M., Rodilla E., Costa J.A., Simon T., Delles C., Dymott J.A., Neisius U., Carty D.M., Fesler P., Muiesan M.L., Salvettia M., Paini A., Tisler A., Zofi, Nemeth K., Marton A., El Haj Othmane T., Cseprekal O., Studinger P., Ibrahim N.N.I.N., Rasool A.H.G., Rahman A.R.A., Wong A.R., Protogerou A.D., Papaioannou T.G., Sfikakis P.P., Fu Y., Hu J., Zhao L., Li N., Jiang X., Ok E., Demirci M.S., Gungor O., Orlova I.A., Blankova Z.N., Seredenina E.M., Ageev F.T., Barinova I.V., Bellien J., Iacob M., Thuillez C., Joannides, Erglis A., Mintale I., Latkovskis G., Berzina M., Zabunova M., Krallisa A., Smulyan H., Safar M., Zhadan A., Tselukyo V., Bregvadze T., Aydin A., Von Kodolitsch Y., MUMC+: HVC Pieken Maastricht Studie (9), Interne Geneeskunde, MUMC+: MA Interne Geneeskunde (3), Promovendi ODB, Epidemiologie, RS: CARIM - R3 - Vascular biology, MUMC+: KIO Kemta (9), Obstetrie & Gynaecologie, The Reference Values for Arterial Measurements Collaboration, Universidade do Minho, and Ege Üniversitesi

Subjects
Adult, Male, medicine.medical_specialty, Percentile, Central pressure, Arteriosclerosis, Systole, Medicina Básica [Ciências Médicas], Population, Aged, Aorta, Arteries, Blood pressure, Humans, Pulse, Age Distribution, Blood Pressure, Blood Pressure Determination, Cardiovascular Diseases, Female, Healthy Volunteers, Middle Aged, Reference Values, Risk Factors, Sex Distribution, Young Adult, Disease, Internal medicine, Diabetes mellitus, Medicine, Young adult, education, Cardiology and Cardiovascular Medicine, education.field_of_study, business.industry, ComputerSystemsOrganization_COMPUTER-COMMUNICATIONNETWORKS, medicine.disease, Pulse pressure, Surgery, ComputingMilieux_MANAGEMENTOFCOMPUTINGANDINFORMATIONSYSTEMS, ComputingMethodologies_PATTERNRECOGNITION, Ciências Médicas::Medicina Básica, InformationSystems_MISCELLANEOUS, business
Abstract

PubMed ID: 25112663, Aims: Estimated central systolic blood pressure (cSBP) and amplification (Brachial SBP-cSBP) are non-invasive measures potentially prognostic of cardiovascular (CV) disease. No worldwide, multiple-device reference values are available. We aimed to establish reference values for a worldwide general population standardizing between the different available methods of measurement. How these values were significantly altered by cardiovascular risk factors (CVRFs) was then investigated. Methods and results: Existing data from population surveys and clinical trials were combined, whether published or not. Reference values of cSBP and amplification were calculatedas percentiles for 'Normal' (no CVRFs) and 'Reference' (any CVRFs) populations. We included 45 436 subjects out of 82 930 that were gathered from 77 studies of 53 centres. Included subjects were apparently healthy, not treated for hypertension or dyslipidaemia, and free from overt CV disease and diabetes. Values of cSBP and amplification were stratified by brachial blood pressure categories and age decade in turn, both being stratifiedbysex. Amplification decreased with age and more so in males than in females. Sex was the most powerful factor associated with amplification with 6.6 mmHg (5.8-7.4) higher amplification in males than in females. Amplification was marginally but significantly influenced by CVRFs, with smoking and dyslipidaemia decreasing amplification, but increased with increasing levels of blood glucose. Conclusion: Typical values of cSBP and amplification in a healthy population and a population free of traditional CVRFs are now available according to age, sex, and brachial BP, providing values included from different devices with a wide geographical representation. Amplification is significantly influenced by CVRFs, but differently in men and women. © 2014 Published on behalf of the European Society of Cardiology.

Published
2014

16. Surveillance of mushroom-related poisonings in Italy

Author

Assisi, F., Settimi, L., Bissoli, M., Borghini, R., Puppa, T. D., Dimasi, V., Ferruzzi, M., Moro, P. A., Georgatos, J., Rebutti, I., Travaglia, A., Severgnini, Paolo, Sesana, F., Milanesi, G., and Davanzo, F.

Published
2014

30. Update: hydrogen cyanamide-related illnesses--Italy, 2002-2004

Author

Settimi, L., Marcello, I., Davanzo, F., Faraoni, L., Miceli, G., Richmond, D., and Calvert, G.M.

Subjects
Health aspects, Pesticides -- Health aspects, Hydrogen cyanide -- Health aspects
Abstract

Hydrogen cyanamide * is used in agriculture as a plant growth regulator and is applied to many deciduous plants to stimulate uniform budbreak after dormancy, resulting in uniform flowering and [...]

Published
2005

34. Progetto Regione Lombardia: Prevenzione dei tumori professionali

Author

Carrer, P, Aiani, R, Ariano, E, Braidi, C, Castoldi, Mr, Cavallo, DOMENICO MARIA GUIDO, Cirla, P, Filipponi, A, Fustinoni, S, Gervasio, A, Mondini, D, Pellican, P, Santucciu, P, Scarpa, M, Settimi, L, Tiso, C, Zito, F, Carreri, V, and Fo, V.

Published
2003

35. Relationship between short-term blood pressure variability and large-artery stiffness in human hypertension.

Author

Schillaci, G, Bilo, G, Pucci, G, Laurent, S, Macquin Mavier, I, Boutouyrie, P, Battista, F, Settimi, L, Desamericq, G, Dolbeau, G, Faini, A, Salvi, P, Mannarino, E, Parati, G, BILO, GRZEGORZ, FAINI, ANDREA, PARATI, GIANFRANCO, Schillaci, G, Bilo, G, Pucci, G, Laurent, S, Macquin Mavier, I, Boutouyrie, P, Battista, F, Settimi, L, Desamericq, G, Dolbeau, G, Faini, A, Salvi, P, Mannarino, E, Parati, G, BILO, GRZEGORZ, FAINI, ANDREA, and PARATI, GIANFRANCO

Abstract

Short-term blood pressure (BP) variability predicts cardiovascular complications in hypertension, but its association with large-artery stiffness is poorly understood and confounded by methodologic issues related to the assessment of BP variations over 24 hours. Carotid-femoral pulse wave velocity (cfPWV) and 24-hour ambulatory BP were measured in 911 untreated, nondiabetic patients with uncomplicated hypertension (learning population) and in 2089 mostly treated hypertensive patients (83% treated, 25% diabetics; test population). Short-term systolic BP (SBP) variability was calculated as the following: (1) SD of 24-hour, daytime, or nighttime SBP; (2) weighted SD of 24-hour SBP; and (3) average real variability (ARV), that is, the average of the absolute differences between consecutive SBP measurements over 24 hours. In the learning population, all of the measures of SBP variability showed a direct correlation with cfPWV (SD of 24-hour, daytime, and nighttime SBP, r 0.17/0.19/0.13; weighted SD of 24-hour SBP, r 0.21; ARV, r 0.26; all P 0.001). The relationship between cfPWV and ARV was stronger than that with 24-hour, daytime, or nighttime SBP (all P 0.05) and similar to that with weighted SD of 24-hour SBP. In the test population, ARV and weighted SD of 24-hour SBP had stronger relationships with cfPWV than SD of 24-hour, daytime, or nighttime SBP. In both populations, SBP variability indices independently predicted cfPWV along with age, 24-hour SBP, and other factors. We conclude that short-term variability of 24-hour SBP shows an independent, although moderate, relation to aortic stiffness in hypertension. This relationship is stronger with measures of BP variability focusing on short-term changes, such as ARV and weighted 24-hour SD.

Published
2012

36. [An experimental evaluation of the efficacy of 4 types of detergents for 3 types of dyes to which workers in color-printing plants are exposed]

Author

Gf, Terzaghi, Settimi L, Peverelli C, Sevosi L, and Piergiorgio Duca

Subjects
Male, Analysis of Variance, Double-Blind Method, Italy, Occupational Exposure, Detergents, Color, Humans, Printing, Ink, Coloring Agents, Hand Disinfection
Abstract

The efficacy of 4 commercial cleansing products was tested with 3 colouring agents widely used in the dyeing industry in a randomised double blind trail involving 8 workers each time. A between-detergents statistically significant difference was observed; the interaction (detergents x colouring agents) was significant. The efficacy of type A detergent was higher for type I-III dyers, while the efficacy of type C detergent, which widely used was lowest.

Published
1996

45. Host-Guest Interactions in Single-Ion Lithium Polymer Electrolyte

Author

Golodnitsky, D., primary, Kovarsky, R., additional, Mazor, H., additional, Rosenberg, Yu., additional, Lapides, I., additional, Peled, E., additional, Wieczorek, W., additional, Plewa, A., additional, Siekierski, M., additional, Kalita, M., additional, Settimi, L., additional, Scrosati, B., additional, and Scanlon, L. G., additional

Published
2007
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49. Mortality study on a cohort of Italian licensed pesticide users

Author

Torchio, P, Lepore, A, Corrao, G, Comba, P, Settimi, L, Belli, S, Magnani, C, di Orio, F, Lepore, AR, CORRAO, GIOVANNI, di Orio, F., Torchio, P, Lepore, A, Corrao, G, Comba, P, Settimi, L, Belli, S, Magnani, C, di Orio, F, Lepore, AR, CORRAO, GIOVANNI, and di Orio, F.

Abstract

This study describes the mortality experience in a cohort of 23,401 farmers, residing in southern Piedmont, Italy, and licensed to use pesticides. From 1970 to 1986 the cohort included 340,794 person-years and 2683 deaths were observed. A strong attenuation of the death risk was found due to the healthy worker effect (seen as an active role in the application for the license by the members of the cohort) and due to the limited comparability of the cohort with respect to the reference population. The standardized mortality ratios (SMRs) were remarkably < 100 for all causes (SMR = 59; 95% confidence interval = 57-61) and for all tumors (SMR = 60; 95% CI 55-64), but they increased with the increasing duration of the follow-up. A risk increase was observed with respect to melanomas and eye tumors in the entire cohort and lymphoma and tumors of the connective tissue in the subcohort of subjects living in villages with mainly arable land

Published
1994

50. Cancer risk among female agricultural workers: A multi-center case-control study

Author

Settimi, L., primary, Comba, P., additional, Carrieri, P., additional, Boffetta, P., additional, Magnani, C., additional, Terracini, B., additional, Andrion, A., additional, Bosia, S., additional, Ciapini, C., additional, De Santis, M., additional, Desideri, E., additional, Fedi, A., additional, Luccoli, L., additional, Maiozzi, P., additional, Masina, A., additional, Perazzo, P.L., additional, and Axelson, O., additional

Published
1999
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