929 results on '"Sessler D"'
Search Results
2. Systematic review and consensus definitions for the Standardised Endpoints in Perioperative Medicine initiative: clinical indicators
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Myles, P., Grocott, M., Biccard, B., Blazeby, J., Boney, O., Chan, M., Diouf, E., Fleisher, L., Kalkman, C., Kurz, A., Moonesinghe, R., Wijeysundera, D., Gan, T.J., Peyton, P., Sessler, D., Tramèr, M., Cyna, A., De Oliveira, G.S., Jr., Wu, C., Jensen, M., Kehlet, H., Botti, M., Haller, G., Cook, T., Neuman, M., Story, D., Gruen, R., Bampoe, S., Evered, L., Scott, D., Silbert, B., van Dijk, D., Grocott, H., Eckenhoff, R., Rasmussen, L., Eriksson, L., Beattie, S., Landoni, G., Leslie, K., Howell, S., Nagele, P., Richards, T., Lamy, A., Lalu, M., Pearse, R., Mythen, M., Canet, J., Moller, A., Gin, T., Schultz, M., Pelosi, P., Gabreu, M., Futier, E., Creagh-Brown, B., Abbott, T., Klein, A., Corcoran, T., Jamie Cooper, D., Dieleman, S., McIlroy, D., Bellomo, R., Shaw, A., Prowle, J., Karkouti, K., Billings, J., Mazer, D., Jayarajah, M., Murphy, M., Bartoszko, J., Sneyd, R., Morris, S., George, R., Shulman, M., Lane-Fall, M., Nilsson, U., Stevenson, N., Cooper, J.D.J., van Klei, W., Cabrini, L., Miller, T., Pace, N., Jackson, S., Buggy, D., Short, T., Riedel, B., Gottumukkala, V., Alkhaffaf, B., Johnson, M., Haller, Guy, Bampoe, Sohail, Cook, Tim, Fleisher, Lee A., Grocott, Michael P.W., Neuman, Mark, Story, David, and Myles, Paul S.
- Published
- 2019
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3. Machine learning to predict myocardial injury and death after non-cardiac surgery
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Nolde, J, primary, Schlaich, M P, additional, Sessler, D I, additional, Mian, A, additional, Corcoran, T B, additional, Chow, C K, additional, Chan, M T V, additional, Borges, F K, additional, Mcgillion, M H, additional, Myles, P S, additional, Mills, N L, additional, Devereaux, P J, additional, and Hillis, G S, additional
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- 2023
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4. A systematic review and consensus definitions for standardised end-points in perioperative medicine: pulmonary complications
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Myles, P., Gan, T.J., Kurz, A., Peyton, P., Sessler, D., Tramèr, M., Cyna, A., De Oliveira, G.S., Jr., Wu, C., Jensen, M., Kehlet, H., Botti, M., Boney, O., Haller, G., Grocott, M., Cook, T., Fleisher, L., Neuman, M., Story, D., Gruen, R., Bampoe, S., Evered, Lis, Scott, D., Silbert, B., van Dijk, D., Kalkman, C., Chan, M., Grocott, H., Eckenhoff, R., Rasmussen, L., Eriksson, L., Beattie, S., Wijeysundera, D., Landoni, G., Leslie, K., Biccard, B., Howell, S., Nagele, P., Richards, T., Lamy, A., Gabreu, M., Klein, A., Corcoran, T., Jamie Cooper, D., Dieleman, S., Diouf, E., McIlroy, D., Bellomo, R., Shaw, A., Prowle, J., Karkouti, K., Billings, J., Mazer, D., Jayarajah, M., Murphy, M., Bartoszko, J., Sneyd, R., Morris, S., George, R., Moonesinghe, R., Shulman, M., Lane-Fall, M., Nilsson, U., Stevenson, N., van Klei, W., Cabrini, L., Miller, T., Pace, N., Jackson, S., Buggy, D., Short, T., Riedel, B., Gottumukkala, V., Alkhaffaf, B., Johnson, M., Abbott, T.E.F., Fowler, A.J., Pelosi, P., Gama de Abreu, M., Møller, A.M., Canet, J., Creagh-Brown, B., Mythen, M., Gin, T., Lalu, M.M., Futier, E., Grocott, M.P., Schultz, M.J., and Pearse, R.M.
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- 2018
- Full Text
- View/download PDF
5. Epidural needle insertion: A large registry analysis
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Bomberg, H., Paquet, N., Huth, A., Wagenpfeil, S., Kessler, P., Wulf, H., Wiesmann, T., Standl, T., Gottschalk, A., Döffert, J., Hering, W., Birnbaum, J., Kutter, B., Winckelmann, J., Liebl-Biereige, S., Meissner, W., Vicent, O., Koch, T., Bürkle, H., Sessler, D. I., Raddatz, A., and Volk, T.
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- 2018
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6. Machine learning to predict myocardial injury and death after non‐cardiac surgery
- Author
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Nolde, J. M., primary, Schlaich, M. P., additional, Sessler, D. I., additional, Mian, A., additional, Corcoran, T. B., additional, Chow, C. K., additional, Chan, M. T. V., additional, Borges, F. K., additional, McGillion, M. H., additional, Myles, P. S., additional, Mills, N. L., additional, Devereaux, P. J., additional, and Hillis, G. S., additional
- Published
- 2023
- Full Text
- View/download PDF
7. A randomised controlled trial of dexmedetomidine for delirium in adults undergoing heart valve surgery
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Wang, H.‐B., primary, Jia, Y., additional, Zhang, C.‐B., additional, Zhang, L., additional, Li, Y.‐N., additional, Ding, J., additional, Wu, X., additional, Zhang, Z., additional, Wang, J.‐H., additional, Wang, Y., additional, Yan, F.‐X., additional, Yuan, S., additional, and Sessler, D. I., additional
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- 2023
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8. Localized or Systemic In Vivo Heat-Inactivation of Human Immunodeficiency Virus (HIV): A Mathematical Analysis
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Pennypacker, C, Perelson, A S, Nys, N, Nelson, G, and Sessler, D I
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- 1993
9. Changes in platelet Bax levels contribute to impaired platelet response to thrombin after cardiopulmonary bypass: prospective observational clinical and laboratory investigations
- Author
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Murase, M, Nakayama, Y, Sessler, D I, Mukai, N, Ogawa, S, and Nakajima, Y
- Published
- 2017
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10. The WHO recommendation for 80% perioperative oxygen is poorly justified
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Volk, T., Peters, J., and Sessler, D. I.
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- 2017
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11. ESICM LIVES 2016: part two: Milan, Italy. 1–5 October 2016
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Sivakumar, S., Taccone, F. S., Desai, K. A., Lazaridis, C., Skarzynski, M., Sekhon, M., Henderson, W., Griesdale, D., Chapple, L., Deane, A., Williams, L., Strickland, R., Lange, K., Heyland, D., Chapman, M., Rowland, M. J., Garry, P., Westbrook, J., Corkill, R., Antoniades, C. A., Pattinson, K. T., Fatania, G., Strong, A. J., Myers, R. B., Lazaridis, C., Jermaine, C. M., Robertson, C. S., Rusin, C. G., Hofmeijer, J., Sondag, L., Tjepkema-Cloostermans, M. C., Beishuizen, A., Bosch, F. H., van Putten, M. J. A. M., Carteron, L., Patet, C., Solari, D., Oddo, M., Ali, M. A., Dias, C., Almeida, R., Vaz-Ferreira, A., Silva, J., Monteiro, E., Cerejo, A., Rocha, A. P., Elsayed, A. A., Abougabal, A. M., Beshey, B. N., Alzahaby, K. M., Pozzebon, S., Ortiz, A. Blandino, Cristallini, S., Lheureux, O., Brasseur, A., Vincent, J. L., Creteur, J., Taccone, F. S., Hravnak, M., Yousef, K., Chang, Y., Crago, E., Friedlander, R. M., Abdelmonem, S. A., Tahon, S. A., Helmy, T. A., Meligy, H. S., Puig, F., Dunn-Siegrist, I., Pugin, J., Gupta, S., Govil, D., Srinivasan, S., Patel, S. J., N, J. K., Gupta, A., Tomar, D. S., Shafi, M., Harne, R., Arora, D. P., Talwar, N., Mazumdar, S., Papakrivou, E. E., Makris, D., Manoulakas, E., Tsolaki, B., Karadodas, B., Zakynthinos, E., Garcia, I. Palacios, Martin, A. Diaz, Encinares, V. Sanchez, Ibañez, M. Pachón, Montero, J. Garnacho, Labrador, G., Cangueiro, T. Cebrero, Poulose, V., Koh, J., Kam, J. W., Yeter, H., Kara, A., Aktepe, O., Topeli, A., Tsolakoglou, I., Intas, G., Stergiannis, P., Kolaros, A. A., Chalari, E., Athanasiadou, E., Martika, A., Fildisis, G., Faivre, V., Mengelle, C., Favier, B., Payen, D., Poppe, A., Winkler, M. S., Mudersbach, E., Schreiber, J., Wruck, M. L., Schwedhelm, E., Kluge, S., Zöllner, C., Tavladaki, T., Spanaki, A. M., Dimitriou, H., Kondili, E., Choulaki, C., Meleti, E., Kafetzopoulos, D., Georgopoulos, D., Briassoulis, G., la Torre, A. García-de, de la Torre-Prados, M. V., Tsvetanova-Spasova, T., Nuevo-Ortega, P., Rueda-Molina, C., Fernández-Porcel, A., Camara-Sola, E., Salido-Díaz, L., García-Alcántara, A., Tavladaki, T., Spanaki, A. M., Dimitriou, H., Kondili, E., Choulaki, C., Meleti, D. E., Kafetzopoulos, D., Georgopoulos, D., Briassoulis, G., Suberviola, B., Riera, J., Rellan, L., Sanchez, M., Robles, J. C., Lopez, E., Vicente, R., Miñambres, E., Santibañez, M., Le Guen, M., Moore, J., Mason, N., Windpassinger, M., Plattner, O., Mascha, E., Sessler, D. I., Research, Outcomes, Melia, U., Fontanet, J., van den Berg, J. P., Struys, M. M. R. F., Vereecke, H. E. M., Jensen, E. W., Rood, P. J. T., van de Schoor, F., van Tertholen, K., Pickkers, P., van den Boogaard, M., Beardow, Z. J., Redhead, H., Paramasivam, K., Numan, T., van den Boogaard, M., Kamper, A. M., Rood, P., Peelen, L. M., Zeman, P. M., Slooter, A. J., van Ewijk, C. E., Jacobs, G. E., Girbes, A. R. J., Myatra, S. N., Harish, M. M., Prabu, N. R., Siddiqui, S., Kulkarni, A. P., Divatia, J. V., Murbach, L. D., Leite, M. A., Osaku, E. F., Costa, C. R. L. M., Pelenz, M., Neitzke, N. M., Moraes, M. M., Jaskowiak, J. L., Silva, M. M. M., Zaponi, R. S., Abentroth, L. R. L., Ogasawara, S. M., Jorge, A. C., Duarte, P. A. D., Hernández-Sánchez, N., Sánchez-Hurtado, L. A., García-Guillen, F. J., Ñamendys-Silva, S. A., Maghsoudi, B., Emami, M., Khosravi, M. B., Zand, F., Tabatabaie, H. R., Masjedi, M., Sabetiyan, G., Mokri, A., Troubleyn, J., Diltoer, M., Jacobs, R., Nguyen, D. N., De Waele, E., De Regt, J., Honoré, P. M., Van Gorp, V., Spapen, H. D., Contreras, R. S., Toapanta, N. D., Moreno, G., Sabater, J., Torrado, H., Gonzalez, M., Marin, M., Farigola, E., Gonzalez, A., Fernandez, J., Vera, A., Gisbert, X., Juliá, C., Uya, J., Corral, L., Elias-Jones, I., Gemmell, L., MacKay, A., Randall, D., Adwaney, A., Blunden, M., Prowle, J. R., Kirwan, C. J., Thomas, N., Martin, A., Owen, H., Darwin, L., Conway, D., Atkinson, D., Sharman, M., Moore, J., Barbanti, C., Amour, J., Gaudard, P., Rozec, B., Mauriat, P., M’rini, M., Leger, P. L., Cambonie, G., Liet, J. M., Girard, C., Laroche, S., Damas, P., Assaf, Z., Loron, G., Lecourt, L., Pouard, P., Randall, D., Adwaney, A., Blunden, M., Prowle, J.R., Kirwan, C. J., Kim, S. H., Na, S., Kim, J., Oh, S. Y., Jung, C. W., Yoo, S. H., Min, S. H., Chung, E. J., Lee, H., Lee, N. J., Lee, K. W., Suh, K. S., Ryu, H. G., Marshall, D. C., Goodson, R. J., Salciccioli, J. D., Shalhoub, J., Potter, E. K., Kirk-Bayley, J., Karanjia, N. D., Forni, L. G., Creagh-Brown, B. C., Bossy, M., Nyman, M., Tailor, A., Creagh-Brown, B., D’Antini, D., Spadaro, S., Valentino, F., Sollitto, F., Cinnella, G., Mirabella, L., Calvo, F. J. Redondo, Bejarano, N., Padilla, D., Baladron, V., Villajero, P., Villazala, R., Redondo, J., Yuste, A. S., Liu, J., Shen, F., Teboul, J. L., Anguel, N., Beurton, A., Bezaz, N., Richard, C., Monnet, X., Fossali, T., Colombo, R., Ottolina, D., Rossetti, M., Mazzucco, C., Marchi, A., Porta, A., Catena, E., Tollisen, K. H., Andersen, G. Ø., Heyerdahl, F., Jacobsen, D., de Waard, M. C., Girbes, A. R. J., van IJzendoorn, M. C. O., Buter, H., Kingma, W. P., Navis, G. J., Boerma, E. C., Rulisek, J., Balik, M., Zacharov, S., Kim, H. S., Jeon, S. J., Namgung, H., Lee, E., Lee, E., Cho, Y. J., Lee, Y. J., Huang, A., Cioccari, L., Luethi, N., Mårtensson, J., Bellomo, R., Forsberg, M., Edman, G., Höjer, J., Forsberg, S., Freile, M. T. Chiquito, Hidalgo, F. N., Molina, J. A. Martinez, Lecumberri, R., Rosselló, A. Figuerola, Travieso, P. Medrano, Leon, G. Tuero, Sanchez, J. Gonzalez, Frias, L. Sahuquillo, Rosello, D. Balsells, Verdejo, J. A. Garcia, Serrano, J. A. Noria, Winterwerp, D., van Galen, T., Vazin, A., Karimzade, I., Zand, A., Ozen, E., Ekemen, S., Akcan, A., Sen, E., Yelken, B. Buyukkidan, Kureshi, N., Fenerty, L., Thibault-Halman, G., Erdogan, M., Walling, S., Green, R. S., Clarke, D. B., Briassoulis, P., Kalimeris, K., Ntzouvani, A., Nomikos, T., Papaparaskeva, K., Politi, E., Kostopanagiotou, G., Crewdson, K., Rehn, M., Weaver, A., Brohi, K., Lockey, D., Wright, S., Thomas, K., Baker, C., Mansfield, L., Stafford, V., Wade, C., Watson, G., Bryant, A., Chadwick, T., Shen, J., Wilkinson, J., Furneval, J., Henderson, A., Hugill, K., Howard, P., Roy, A., Bonner, S., Baudouin, S., Ramírez, C. Sánchez, Escalada, S. Hípola, Viera, M. A. Hernández, Santana, M. Cabrera, Balcázar, L. Caipe, Monroy, N. Sangil, Campelo, F. Artiles, Vázquez, C. F. Lübbe, Santana, P. Saavedra, Santana, S. Ruiz, Carteron, L., Patet, C., Quintard, H., Solari, D., Bouzat, P., Oddo, M., Wollersheim, T., Malleike, J., Haas, K., Carbon, N., Schneider, J., Birchmeier, C., Fielitz, J., Spuler, S., Weber-Carstens, S., Enseñat, L., Pérez-Madrigal, A., Saludes, P., Proença, L., Gruartmoner, G., Espinal, C., Mesquida, J., Huber, W., Eckmann, M., Elkmann, F., Gruber, A., Lahmer, T., Mayr, U., Herner, A., Schellnegger, R., Schneider, J., Schmid, R. M., Ayoub, W., Samy, W., Esmat, A., Battah, A., Mukhtar, S., Mongkolpun, W., Cortés, D. Orbegozo, Cordeiro, C. P. R., Vincent, J. L., Creteur, J., Funcke, S., Groesdonk, H., Saugel, B., Wagenpfeil, G., Wagenpfeil, S., Reuter, D. A., Fernandez, M. M., Fernandez, R., Magret, M., González-Castro, A., Bouza, M. T., Ibañez, M., García, C., Balerdi, B., Mas, A., Arauzo, V., Añón, J. M., Ruiz, F., Ferreres, J., Tomás, R., Alabert, M., Tizón, A. I., Altaba, S., Llamas, N., Goligher, E C., Fan, E., Herridge, M., Vorona, S., Sklar, M., Dres, M., Rittayamai, N., Lanys, A., Urrea, C., Tomlinson, G., Reid, W. D., Rubenfeld, G. D., Kavanagh, B. P., Brochard, L. J., Ferguson, N. D., Neto, A. Serpa, de Abreu, M. Gama, Pelosi, P., Schultz, M. J., Guérin, C., Papazian, L., Reignier, J., Ayzac, L., Loundou, A., Forel, J. M., Rolland-Debord, C., Bureau, C., Poitou, T., Clavel, M., Perbet, S., Terzi, N., Kouatchet, A., Similowski, T., Demoule, A., Hunfeld, N., Trogrlic, Z., Ladage, S., Osse, R. J., Koch, B., Rietdijk, W., Devlin, J., van der Jagt, M., Picetti, E., Ceccarelli, P., Mensi, F., Malchiodi, L., Risolo, S., Rossi, I., Antonini, M. V., Servadei, F., Caspani, M. L., Roquilly, A., Lasocki, S., Seguin, P., Geeraerts, T., Perrigault, P. F., Dahyot-Fizelier, C., Paugam-Burtz, C., Cook, F., Cinotti, R., dit Latte, D. Demeure, Mahe, P. J., Fortuit, C., Feuillet, F., Asehnoune, K., Marzorati, C., Spina, S., Scaravilli, V., Vargiolu, A., Riva, M., Giussani, C., Sganzerla, E., Citerio, G., Barbadillo, S., de Molina, F. J. González, Álvarez-Lerma, F., Rodríguez, A., Zakharkina, T., Martin-Loeches, I., Matamoros, S., Povoa, P., Torres, A., Kastelijn, J., Hofstra, J. J., de Jong, M., Schultz, M., Sterk, P., Artigas, A., Bos, L. J., Moreau, A. S., Martin-Loeches, I., Povoa, P., Salluh, J., Rodriguez, A., Nseir, S., de Jong, E., van Oers, J. A., Beishuizen, A., Girbes, A. R. J., Nijsten, M. W. N., de Lange, D. W., Bonvicini, D., Labate, D., Benacchio, L., Olivieri, A., Pizzirani, E., Lopez-Delgado, J. C., Gonzalez-Romero, M., Fuentes-Mila, V., Berbel-Franco, D., Romera-Peregrina, I., Martinez-Pascual, A., Perez-Sanchez, J., Abellan-Lencina, R., Ávila-Espinoza, R. E., Moreno-Gonzalez, G., Sbraga, F., Griffiths, S., Grocott, M. P. W., Creagh-Brown, B., Doyle, J., Wilkerson, P., Soon, Y., Huddart, S., Dickinson, M., Riga, A., Zuleika, A., Miyamoto, K., Kawazoe, Y., Morimoto, T., Yamamoto, T., Fuke, A., Hashimoto, A., Koami, H., Beppu, S., Katayama, Y., Ito, M., Ohta, Y., Yamamura, H., Rygård, S. L., Holst, L B., Wetterslev, J., Johansson, P. I., Perner, A., Soliman, I. W., de Lange, D. W., van Dijk, D., van Delden, J. J. M., Cremer, O. L., Slooter, A. J. C., Peelen, L. M., McWilliams, D., Snelson, C., Neves, A. Das, Loudet, C. I., Busico, M., Vazquez, D., Villalba, D., Veronesi, M., Lischinsky, A., López, F. J. L., Mori, L. Benito, Plotnikow, G., Díaz, A., Giannasi, S., Hernandez, R., Krzisnik, L., Cecotti, C., Viola, L., Lopez, R., Sottile, J. P., Benavent, G., Estenssoro, E., Chen, C. M., Lai, C. C., Cheng, K. C., Chou, W., Chan, K. S., Roeker, L. E., Horkan, C. M., Gibbons, F. K., Christopher, K. B., Weijs, P. J. M., Mogensen, K. M., Rawn, J. D., Robinson, M. K., Christopher, K. B., Tang, Z., Qiu, C., Ouyang, B., Cai, C., Guan, X., Regueira, T., Cea, L., Carlos, S. Juan, Elisa, B., Puebla, C., Vargas, A., Poulsen, M. K., Thomsen, L. P., Kjærgaard, S., Rees, S. E., Karbing, D. S., Wollersheim, T., Frank, S., Müller, M. C., Carbon, N. M., Skrypnikov, V., Pickerodt, P. A., Falk, R., Mahlau, A., Weber-Carstens, S., Lee, A., Inglis, R., Morgan, R., Barker, G., Kamata, K., Abe, T., Saitoh, D., Tokuda, Y., Green, R. S., Butler, M. B., Erdogan, M., Hwa, H. Tae, Gil, L. Jae, Vaquero, R. Hernández, Rodriguez-Ruiz, E., Lago, A. Lopez, Allut, J. L. Garcia, Gestal, A. Estany, Gonzalez, M. A. Garcia, Thomas-Rüddel, D. O., Schwarzkopf, D., Fleischmann, C., Reinhart, K., Suwanpasu, S., Sattayasomboon, Y., Filho, N. M. Filgueiras, Oliveira, J. C. A., Ballalai, C. S., De Lucia, C. V., Araponga, G. P., Veiga, L. N., Silva, C. S., Garrido, M. E., Ramos, B. B., Ricaldi, E. F., Gomes, S. S., Gemmell, L., MacKay, A., Wright, C., Docking, R. I., Doherty, P., Black, E., Stenhouse, P., Plummer, M. P., Finnis, M. E., Phillips, L. K., Kar, P., Bihari, S., Biradar, V., Moodie, S., Horowitz, M., Shaw, J. E., Deane, A. M., Yatabe, T., Inoue, S., Sakaguchi, M., Egi, M., Abdelhamid, Y. Ali, Plummer, M. P., Finnis, M. E., Phillips, L. K., Kar, P., Bihari, S., Biradar, V., Moodie, S., Horowitz, M., Shaw, J. E., Deane, A. M., Hokka, M., Egi, M., Mizobuchi, S., Kar, P., Plummer, M., Abdelhamid, Y. Ali, Giersch, E., Summers, M., Hatzinikolas, S., Heller, S., Chapman, M., Jones, K., Horowitz, M., Deane, A., Schweizer, R., Jacquet-Lagreze, M., Portran, P., Junot, S., Allaouchiche, B., Fellahi, J. L., Guerci, P., Ergin, B., Kapucu, A., Ince, C., Cioccari, L., Luethi, N., Crisman, M., Bellomo, R., Mårtensson, J., Shinotsuka, C. Righy, Fagnoul, D., Brasseur, A., Orbegozo, D., Vincent, J. L., Preiser, J. C., Preiser, J. C., Lheureux, O., Thooft, A., Brimioulle, S., Vincent, J. L., Iwasaka, H., Tahara, S., Nagamine, M., Ichigatani, A., Cabrera, A. Rugerio, Zepeda, E. Monares, Granillo, J. Franco, Sánchez, J. S. Aguirre, Montoya, A. A. Tanaka, Montenegro, A. Pedraza, Blanco, G. A. Gálvez, Robles, C. M. Coronado, Drolz, A., Horvatits, T., Roedl, K., Rutter, K., Kluge, S., Funk, G. C., Schneeweiss, B., Fuhrmann, V., Sabetian, G., Pooresmaeel, F., Zand, F., Ghaffaripour, S., Farbod, A., Tabei, H., Taheri, L., Anandanadesan, R., Metaxa, V., Teixeira, C., Pereira, S. M., Hernández-Marrero, P., Carvalho, A. S., Beckmann, M., Hartog, C. S., Schwarzkopf, D., Raadts, A., Robertsen, A., Førde, R., Skaga, N. O., Helseth, E., Honeybul, S., Ho, K., Lopez, P. Martinez, Gonzalez, M. Nieto, Ortega, P. Nuevo, Sola, E. Camara, Spasova, T., de la Torre-Prados, M. V., Kopecky, O., Rusinova, K., Waldauf, P., Cepeplikova, Z., Balik, M., Domínguez, J. Palamidessi, Almudevar, P. Matia, Carmona, S. Alcántara, Muñoz, J. J. Rubio, Castañeda, D. Palacios, Abellán, A. 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S., Lozano, A., Lheureux, O., Badenes, R., Vincent, J. L., Creteur, J., Taccone, F. S., Gallaher, C., Cattlin, S., Gordon, S., Picard, J., Fontana, V., Bond, O., Nobile, L., Vincent, J. L., Creteur, J., Taccone, F. S., Mrozek, S., Delamarre, L., Capilla, F., Al-Saati, T., Fourcade, O., Geeraerts, T., Dominguez-Berrot, A. M., Gonzalez-Vaquero, M., Vallejo-Pascual, M. E., Gupta, D., Ivory, B. D., Chopra, M., McCarthy, J., Felderhof, C. L., MacNeil, C., Rubulotta, F., Waldauf, P., Maggiorini, M., Duska, F., Fumis, R. R. L., Junior, J. M. Vieira, Amarante, G., Skorko, A., Sanders, S., Aron, J., Kroll, R. J., Redfearn, C., Krishnan, P., Khalil, J. E., Kovari, F., Kongpolprom, N., Gulia, V., Lourenço, E., Melão, L., Duro, C., Baptista, G., Alves, A., Arminda, B., Rodrigues, M., Marreiros, A., Granja, C., Hayward, J., Baldwin, F., Gray, R., Katinakis, P. A., Stijf, M., Ten Kleij, M., Jansen-Frederiks, M., Broek, R., de Bruijne, M., Spronk, P. E., Sinha, K., Luney, M., Palmer, K., Keating, L., Abu-Habsa, M., Bahl, R., Baskaralingam, N., Ahmad, A., Kanapeckaite, L., Bhatti, P., Glace, S., Jeyabraba, S., Lewis, H. F., Kostopoulos, A., Raja, M., West, A., Ely, A., Turkoglu, L. M., Zolfaghari, P., Baptista, J. P., Marques, M. P., Martins, P., Pimentel, J., Gupta, D., Su, Y. C., Villacres, S., Stone, M. E., Parsikia, A., Medar, S., O’Dea, K. P., Porter, J., Tirlapur, N., Jonathan, J. M., Singh, S., Takata, M., Abu-Habsa, M., Ahmad, A., McWhirter, E., Lyon, R., Hariz, M. L., Azmi, E., Alkhan, J., Honeybul, S., Movsisyan, V., Petrikov, S., Marutyan, Z., Aliev, I., Evdokimov, A., Antonucci, E., Merz, T., Hartmann, C., Pelosi, P., Calzia, E., Radermacher, P., Nußbaum, B., Hartmann, C., Huber-Lang, M., Gröger, M., Radermacher, P., Nußbaum, B., Nußbaum, B., Antonucci, E., Calzia, E., Pelosi, P., Radermacher, P., Hartmann, C., Svoren-Jabalera, E., Davenport, E. E., Humburg, P., Knight, J., Hinds, C. J., Jun, I. J., Kim, W. J., Lee, E. H., Besch, G., Perrotti, A., Puyraveau, M., Carteron, L., Baltres, M., Samain, E., Chocron, S., Pili-Floury, S., Plata-Menchaca, E. P., Sabater-Riera, J., Estruch, M., Boza, E., Sbraga, F., Toscana-Fernández, J., Bruguera-Pellicer, E., Ordoñez-Llanos, J., Pérez-Fernández, X. L., Cavaleiro, P., Tralhão, A., Arrigo, M., Lopes, J.-P., Lebrun, M., Cholley, B., PerezVela, J. L., MarinMateos, H., Rivera, J. J. Jimenez, Llorente, M. A. Alcala, De Marcos, B. Gonzalez, Fernandez, F. J. Gonzalez, Laborda, C. Garcia, Zamora, D. Fernandez, Delgado, J. C. Lopez, Imperiali, C., Berbel-Franco, D., Dastis, M., Moreno-Gonzalez, G., Perez-Sanchez, J., Romera-Peregrina, I., Abellan-Lencina, R., Martinez-Pascual, A., Fuentes-Mila, V., Gonzalez-Romero, M., Górka, J., Górka, K., Iwaniec, T., Frołow, M., Polok, K., Fronczek, J., Kózka, M., Musiał, J., Szczeklik, W., Pérez, A. González, Ordoñez, P. Florez, Giribet, A., Cuervo, M. A. Alonso, Cuervo, R. Alonso, Esteban, M. A. Rodriguez, Fraile, L. Iglesias, Mittelbrum, C. Ponte, Albaiceta, G. Muñiz, Ampatzidou, F., Sileli, M., Kehagioglou, G., Madesis, A., Karaiskos, T., Moursia, C., Maleoglou, H., Leleki, K., Drossos, G., Uz, Z., Ince, Y., Papatella, R., Bulent, E., Guerci, P., Ince, C., De Mol, B., Vicka, V., Gineityte, D., Ringaitiene, D., Norkiene, I., Sipylaite, J., Möller, C., Fleischmann, C., Thomas-Rueddel, D. O., Vlasakov, V., Rochwerg, B., Theurer, P., Gattinoni, L., Reinhart, K., Hartog, C. S., Pérez, A. González, Al Sibai, J. Zanabili, Camblor, P. Martinez, Fernandez, P. Alvarez, Gala, J. M. García, Guisasola, J. Silba, Albaiceta, G. Muñiz, Tamura, T., Yatabe, T., Miyajima, I., Yamashita, K., Yokoyama, M., Ampatzidou, F., Kehagioglou, G., Dalampini, E., Nastou, M., Baddour, A., Ignatiadis, A., Asteri, T., Drossos, G., Hathorn, K. E., Purtle, S. W., Horkan, C. M., Gibbons, F. K., Christopher, K. B., Viana, M. V., Tonietto, T. A., Gross, L. A., Costa, V. L., Tavares, A. L. J., Lisboa, B. O., Moraes, R. B., Vieira, S. R., Viana, L. V., Azevedo, M. J., Ceniccola, G. D., Pequeno, R. S. F., Holanda, T. P., Mendonça, V. S., Araújo, W. M. C., Carvalho, L. S. F., Segaran, E., Vickers, L., Brinchmann, K., Wignall, I., Rubulotta, F., De Brito-Ashurst, I., del Olmo, R., Esteban, M. J., Vaquerizo, C., Carreño, R., Gálvez, V., Kaminsky, G., Nieto, B., Fuentes, M., De la Torre, M. A., Torres, E., Alonso, A., Velayos, C., Saldaña, T., Escribá, A., GRIP, J., Kölegård, R., Sundblad, P., Rooyackers, O., Naser, Ben, Jaziri, F., Jazia, A. Ben, Barghouth, M., Hentati, O., Skouri, W., El Euch, M., Mahfoudhi, M., Turki, S., Abdelghni, K. Ben, Abdallah, Ben, Maha, B. N. M., Cánovas, J., Sotos, F., López, A., Lorente, M., Burruezo, A., Torres, D., Polok, K., Włudarczyk, A., Górka, J., Hałek, A., Musiał, J., Szczeklik, W., Jazia, A. Ben, Jaziri, F., Bargouth, M., Bennasr, M., Turki, S., Abdelghani, K. Ben, Abdallah, T. Ben, de Grooth, H. J., Geenen, I. L., Parienti, J. J., Straaten, H. M. Oudemans-van, Shum, H. P., King, H. S., Chan, K. C., Yan, W. W., Londoño, J. Gonzalez, Cardenas, C. Lorencio, Pedrosa, M. Morales, Gubianas, C. Murcia, Bertolin, C. Fuster, Batllori, N. Vila, Sirvent, J. M., Wykes, K., Jack, J., Morgan, P., Mukhopadhyay, A., Chan, H. Y., Kowitlawakul, Y., Remani, D., Leong, C. S. F., Henry, C. J., Puthucheary, Z. A., Mendsaikhan, N., Begzjav, T., Lundeg, G., Dünser, M., Espinoza, E. D. Valenzuela, Welsh, S. P., Motta, M. F., Guerra, E., Zerpa, M. C. l., Zechner, F., Furche, M., Berdaguer, F., Birri, P. N. Rubatto, Risso-Vazquez, A., Dubin, A., Masevicius, F. D., Greaney, D., Magee, A., Fitzpatrick, G., Lugo-Cob, R. G., Sánchez-Hurtado, L. A., Arvizu-Tachiquín, P. C., Tejeda-Huezo, B. C., Cano-Oviedo, A. A., Baltazar-Torres, J. A., Aydogan, M. S., Togal, T., Taha, A., Chai, H. Z., Kam, C., Razali, S. S. Yang, Sivasamy, V., Kuan, L. Y., Poulose, V., Morales, M. A. Lopez, Castro, S., Pires, T., Melão, L., Krystopchuk, A., Pereira, I., Granja, C., Taniguchi, L. U., Pires, E. M. C., Vieira, Jr, J. M., Azevedo, L. C. P., Nurses of the Central and General ICUs of Shiraz Namazi Hospital, Sedation an Delirium Group Hospital Universitari de Bellvitge, SPACeR group (Surrey Peri-operative, Anaesthesia and Critical Care Collaborative Research Group), for the PRoVENT investigators and the PROVE Network, SEMICYUC/GETGAG Working Group, TAVeM study group, POPC-CB investigators, DESIRE (DExmedetomidine for Sepsis in ICU Randomized Evaluation) Trial Investigators, GEMINI, Bioethics work group of SEMICYUC, The FINNAKI Study Group, Queen Square Neuroanaesthesia and Neurocritical Care Resreach Group, Renal Transplantation HUVR, GEMINI, EDISVAL Group, EDISVAL Group, PLUG Working group, TAVeM study Group, The FINNAKI Study Group, on behalf of Department of Professional Development, ESICM, Critical Care Research Group, SIRAKI group, and Grupo ESBAGA
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- 2016
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12. Tranexamic Acid in Patients Undergoing Noncardiac Surgery
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Devereaux, PJ, Marcucci, M, Painter, TW, Conen, D, Lomivorotov, V, Sessler, D, Chan, MT, Borges, FK, Martinez-Zapata, MJ, Wang, C-Y, Xavier, D, Ofori, SN, Wang, MK, Efremov, S, Landoni, G, Kleinlugtenbelt, Y, Szczeklik, W, Schmartz, D, Garg, AX, Short, TG, Wittmann, M, Meyhoff, CS, Amir, M, Torres, D, Patel, A, Duceppe, E, Ruetzler, K, Parlow, JL, Tandon, V, Fleischmann, E, Polanczyk, CA, Lamy, A, Astrakov, S, Rao, M, Wu, WKK, Bhatt, K, de Nadal, M, Likhvantsev, VV, Paniagua, P, Aguado, HJ, Whitlock, RP, McGillion, MH, Prystajecky, M, Vincent, J, Eikelboom, J, Copland, I, Balasubramanian, K, Turan, A, Bangdiwala, S, Stillo, D, Gross, PL, Cafaro, T, Alfonsi, P, Roshanov, PS, Belley-Cote, EP, Spence, J, Richards, T, VanHelder, T, McIntyre, W, Guyatt, G, Yusuf, S, Leslie, K, Devereaux, PJ, Marcucci, M, Painter, TW, Conen, D, Lomivorotov, V, Sessler, D, Chan, MT, Borges, FK, Martinez-Zapata, MJ, Wang, C-Y, Xavier, D, Ofori, SN, Wang, MK, Efremov, S, Landoni, G, Kleinlugtenbelt, Y, Szczeklik, W, Schmartz, D, Garg, AX, Short, TG, Wittmann, M, Meyhoff, CS, Amir, M, Torres, D, Patel, A, Duceppe, E, Ruetzler, K, Parlow, JL, Tandon, V, Fleischmann, E, Polanczyk, CA, Lamy, A, Astrakov, S, Rao, M, Wu, WKK, Bhatt, K, de Nadal, M, Likhvantsev, VV, Paniagua, P, Aguado, HJ, Whitlock, RP, McGillion, MH, Prystajecky, M, Vincent, J, Eikelboom, J, Copland, I, Balasubramanian, K, Turan, A, Bangdiwala, S, Stillo, D, Gross, PL, Cafaro, T, Alfonsi, P, Roshanov, PS, Belley-Cote, EP, Spence, J, Richards, T, VanHelder, T, McIntyre, W, Guyatt, G, Yusuf, S, and Leslie, K
- Abstract
BACKGROUND: Perioperative bleeding is common in patients undergoing noncardiac surgery. Tranexamic acid is an antifibrinolytic drug that may safely decrease such bleeding. METHODS: We conducted a trial involving patients undergoing noncardiac surgery. Patients were randomly assigned to receive tranexamic acid (1-g intravenous bolus) or placebo at the start and end of surgery (reported here) and, with the use of a partial factorial design, a hypotension-avoidance or hypertension-avoidance strategy (not reported here). The primary efficacy outcome was life-threatening bleeding, major bleeding, or bleeding into a critical organ (composite bleeding outcome) at 30 days. The primary safety outcome was myocardial injury after noncardiac surgery, nonhemorrhagic stroke, peripheral arterial thrombosis, or symptomatic proximal venous thromboembolism (composite cardiovascular outcome) at 30 days. To establish the noninferiority of tranexamic acid to placebo for the composite cardiovascular outcome, the upper boundary of the one-sided 97.5% confidence interval for the hazard ratio had to be below 1.125, and the one-sided P value had to be less than 0.025. RESULTS: A total of 9535 patients underwent randomization. A composite bleeding outcome event occurred in 433 of 4757 patients (9.1%) in the tranexamic acid group and in 561 of 4778 patients (11.7%) in the placebo group (hazard ratio, 0.76; 95% confidence interval [CI], 0.67 to 0.87; absolute difference, -2.6 percentage points; 95% CI, -3.8 to -1.4; two-sided P<0.001 for superiority). A composite cardiovascular outcome event occurred in 649 of 4581 patients (14.2%) in the tranexamic acid group and in 639 of 4601 patients (13.9%) in the placebo group (hazard ratio, 1.02; 95% CI, 0.92 to 1.14; upper boundary of the one-sided 97.5% CI, 1.14; absolute difference, 0.3 percentage points; 95% CI, -1.1 to 1.7; one-sided P = 0.04 for noninferiority). CONCLUSIONS: Among patients undergoing noncardiac surgery, the incidence of the composi
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- 2022
13. Rationale and design of the PeriOperative ISchemic Evaluation-3 (POISE-3): a randomized controlled trial evaluating tranexamic acid and a strategy to minimize hypotension in noncardiac surgery
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Marcucci, M, Painter, TW, Conen, D, Leslie, K, Lomivorotov, VV, Sessler, D, Chan, MT, Borges, FK, Zapata, MJM, Wang, CY, Xavier, D, Ofori, SN, Landoni, G, Efremov, S, Kleinlugtenbelt, Y, Szczeklik, W, Schmartz, D, Garg, AX, Short, TG, Wittmann, M, Meyhoff, CS, Amir, M, Torres, D, Patel, A, Duceppe, E, Ruetzler, K, Parlow, JL, Tandon, V, Wang, MK, Fleischmann, E, Polanczyk, CA, Jayaram, R, Astrakov, S, Rao, M, VanHelder, T, Wu, WKK, Cheong, CC, Ayad, S, Abubakirov, M, Kirov, M, Bhatt, K, de Nadal, M, Likhvantsev, V, Iglesisas, PP, Aguado, HJ, McGillion, M, Lamy, A, Whitlock, RP, Roshanov, P, Stillo, D, Copland, I, Vincent, J, Balasubramanian, K, Bangdiwala, S, Biccard, B, Kurz, A, Srinathan, S, Petit, S, Eikelboom, J, Richards, T, Gross, PL, Alfonsi, P, Guyatt, G, Belley-Cote, E, Spence, J, McIntyre, W, Yusuf, S, Devereaux, PJ, Marcucci, M, Painter, TW, Conen, D, Leslie, K, Lomivorotov, VV, Sessler, D, Chan, MT, Borges, FK, Zapata, MJM, Wang, CY, Xavier, D, Ofori, SN, Landoni, G, Efremov, S, Kleinlugtenbelt, Y, Szczeklik, W, Schmartz, D, Garg, AX, Short, TG, Wittmann, M, Meyhoff, CS, Amir, M, Torres, D, Patel, A, Duceppe, E, Ruetzler, K, Parlow, JL, Tandon, V, Wang, MK, Fleischmann, E, Polanczyk, CA, Jayaram, R, Astrakov, S, Rao, M, VanHelder, T, Wu, WKK, Cheong, CC, Ayad, S, Abubakirov, M, Kirov, M, Bhatt, K, de Nadal, M, Likhvantsev, V, Iglesisas, PP, Aguado, HJ, McGillion, M, Lamy, A, Whitlock, RP, Roshanov, P, Stillo, D, Copland, I, Vincent, J, Balasubramanian, K, Bangdiwala, S, Biccard, B, Kurz, A, Srinathan, S, Petit, S, Eikelboom, J, Richards, T, Gross, PL, Alfonsi, P, Guyatt, G, Belley-Cote, E, Spence, J, McIntyre, W, Yusuf, S, and Devereaux, PJ
- Abstract
BACKGROUND: For patients undergoing noncardiac surgery, bleeding and hypotension are frequent and associated with increased mortality and cardiovascular complications. Tranexamic acid (TXA) is an antifibrinolytic agent with the potential to reduce surgical bleeding; however, there is uncertainty about its efficacy and safety in noncardiac surgery. Although usual perioperative care is commonly consistent with a hypertension-avoidance strategy (i.e., most patients continue their antihypertensive medications throughout the perioperative period and intraoperative mean arterial pressures of 60 mmHg are commonly accepted), a hypotension-avoidance strategy may improve perioperative outcomes. METHODS: The PeriOperative Ischemic Evaluation (POISE)-3 Trial is a large international randomized controlled trial designed to determine if TXA is superior to placebo for the composite outcome of life-threatening, major, and critical organ bleeding, and non-inferior to placebo for the occurrence of major arterial and venous thrombotic events, at 30 days after randomization. Using a partial factorial design, POISE-3 will additionally determine the effect of a hypotension-avoidance strategy versus a hypertension-avoidance strategy on the risk of major cardiovascular events, at 30 days after randomization. The target sample size is 10,000 participants. Patients ≥45 years of age undergoing noncardiac surgery, with or at risk of cardiovascular and bleeding complications, are randomized to receive a TXA 1 g intravenous bolus or matching placebo at the start and at the end of surgery. Patients, health care providers, data collectors, outcome adjudicators, and investigators are blinded to the treatment allocation. Patients on ≥ 1 chronic antihypertensive medication are also randomized to either of the two blood pressure management strategies, which differ in the management of patient antihypertensive medications on the morning of surgery and on the first 2 days after surgery, and in the targe
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- 2022
14. Effect of a Perioperative Hypotension-Avoidance Strategy Versus a Hypertension-Avoidance Strategy on the Risk of Acute Kidney Injury: A Clinical Research Protocol for a Substudy of the POISE-3 Randomized Clinical Trial
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Garg, AX, Cuerden, M, Aguado, H, Amir, M, Belley-Cote, EP, Bhatt, K, Biccard, BM, Borges, FK, Chan, M, Conen, D, Duceppe, E, Efremov, S, Eikelboom, J, Fleischmann, E, Giovanni, L, Gross, P, Jayaram, R, Kirov, M, Kleinlugtenbelt, Y, Kurz, A, Lamy, A, Leslie, K, Likhvantsev, V, Lomivorotov, V, Marcucci, M, Jose Martinez-Zapata, M, McGillion, M, McIntyre, W, Meyhoff, C, Ofori, S, Painter, T, Paniagua, P, Parikh, C, Parlow, J, Patel, A, Polanczyk, C, Richards, T, Roshanov, P, Schmartz, D, Sessler, D, Short, T, Sontrop, JM, Spence, J, Srinathan, S, Stillo, D, Szczeklik, W, Tandon, V, Torres, D, Van Helder, T, Vincent, J, Wang, CY, Wang, M, Whitlock, R, Wittmann, M, Xavier, D, Devereaux, PJ, Garg, AX, Cuerden, M, Aguado, H, Amir, M, Belley-Cote, EP, Bhatt, K, Biccard, BM, Borges, FK, Chan, M, Conen, D, Duceppe, E, Efremov, S, Eikelboom, J, Fleischmann, E, Giovanni, L, Gross, P, Jayaram, R, Kirov, M, Kleinlugtenbelt, Y, Kurz, A, Lamy, A, Leslie, K, Likhvantsev, V, Lomivorotov, V, Marcucci, M, Jose Martinez-Zapata, M, McGillion, M, McIntyre, W, Meyhoff, C, Ofori, S, Painter, T, Paniagua, P, Parikh, C, Parlow, J, Patel, A, Polanczyk, C, Richards, T, Roshanov, P, Schmartz, D, Sessler, D, Short, T, Sontrop, JM, Spence, J, Srinathan, S, Stillo, D, Szczeklik, W, Tandon, V, Torres, D, Van Helder, T, Vincent, J, Wang, CY, Wang, M, Whitlock, R, Wittmann, M, Xavier, D, and Devereaux, PJ
- Abstract
BACKGROUND: Most patients who take antihypertensive medications continue taking them on the morning of surgery and during the perioperative period. However, growing evidence suggests this practice may contribute to perioperative hypotension and a higher risk of complications. This protocol describes an acute kidney injury substudy of the Perioperative Ischemic Evaluation-3 (POISE-3) trial, which is testing the effect of a perioperative hypotension-avoidance strategy versus a hypertension-avoidance strategy in patients undergoing noncardiac surgery. OBJECTIVE: To conduct a substudy of POISE-3 to determine whether a perioperative hypotension-avoidance strategy reduces the risk of acute kidney injury compared with a hypertension-avoidance strategy. DESIGN: Randomized clinical trial with 1:1 randomization to the intervention (a perioperative hypotension-avoidance strategy) or control (a hypertension-avoidance strategy). INTERVENTION: If the presurgery systolic blood pressure (SBP) is <130 mmHg, all antihypertensive medications are withheld on the morning of surgery. If the SBP is ≥130 mmHg, some medications (but not angiotensin receptor blockers [ACEIs], angiotensin receptor blockers [ARBs], or renin inhibitors) may be continued in a stepwise manner. During surgery, the patients' mean arterial pressure (MAP) is maintained at ≥80 mmHg. During the first 48 hours after surgery, some antihypertensive medications (but not ACEIs, ARBs, or renin inhibitors) may be restarted in a stepwise manner if the SBP is ≥130 mmHg. CONTROL: Patients receive their usual antihypertensive medications before and after surgery. The patients' MAP is maintained at ≥60 mmHg from anesthetic induction until the end of surgery. SETTING: Recruitment from 108 centers in 22 countries from 2018 to 2021. PATIENTS: Patients (~6800) aged ≥45 years having noncardiac surgery who have or are at risk of atherosclerotic disease and who routinely take antihypertensive medications. MEASUREMENTS: The primary outcom
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- 2022
15. Detection of postoperative vital signs abnormalities on a surgical ward using conventional and remote automated monitoring
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McGillion MH, Marcucci M, Borges FK, Conen D, Coleman B, Gregus K, Parvaneh S, Bessisow A, Patel A, Harsha P, Ouellette C, Ofori S, Sessler D, Devereaux PJ.
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- 2022
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16. Core Outcome Measures for Perioperative and Anaesthetic Care (COMPAC): a modified Delphi process to develop a core outcome set for trials in perioperative care and anaesthesia
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Boney, Oliver, primary, Moonesinghe, S. Ramani, additional, Myles, Paul S., additional, Grocott, Michael P.W., additional, Bartoszko, J., additional, Beattie, W.S., additional, Bellomo, R., additional, Buggy, D., additional, Cabrini, L., additional, Canet, J., additional, Cook, T., additional, Cooper, D.J., additional, Corcoran, T., additional, Devereaux, P.J., additional, Eckenhoff, R., additional, Evered, L., additional, Gan, T.J., additional, Gin, T., additional, Grocott, H., additional, Haller, G., additional, Howell, S., additional, Jayarajah, M., additional, Kalkman, C., additional, Karkouti, K., additional, Kavanagh, B., additional, Klein, A., additional, Landoni, G., additional, Leslie, K., additional, McIlroy, D.R., additional, Mazer, D., additional, Moller, A., additional, Mythen, M., additional, Neuman, M., additional, Pearse, R., additional, Peyton, P., additional, Prowle, J., additional, Richards, T., additional, Scott, D.A., additional, Sessler, D., additional, Shaw, A., additional, Short, T., additional, Shulman, M., additional, Silbert, B., additional, Singer, M., additional, Sneyd, J.R., additional, Story, D., additional, van Dijk, D., additional, and van Klei, W., additional
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- 2022
- Full Text
- View/download PDF
17. Sweating and Vasoconstriction Thresholds during Propofol Sedation
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Leslie, K., Sessler, D. I., Bjorksten, A. R., Ozaki, M., Schroeder, M., Lin, S., Zeisberger, Eugen, editor, Schönbaum, Eduard, editor, and Lomax, Peter, editor
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- 1994
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18. Epidural Anesthesia Increases Apparent Leg Temperature and Decreases the Shivering Threshold
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Ozaki, M., Emerick, T., Sessler, D. I., Walters, K., Schroeder, M., Zeisberger, Eugen, editor, Schönbaum, Eduard, editor, and Lomax, Peter, editor
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- 1994
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19. Epidural and Spinal Anesthesia Alter Thermoregulatory Response Thresholds
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Schroeder, M., Ozaki, M., Kurz, A., Sessler, D. I., Lenhardt, R., Moayeri, A., Noyes, K. M., Rotheneder, E., Kurz, M., Zeisberger, Eugen, editor, Schönbaum, Eduard, editor, and Lomax, Peter, editor
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- 1994
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20. Heat Balance and Distribution during Epidural Anesthesia
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Hynson, J. M., Sessler, D. I., Glosten, B., McGuire, J., Zeisberger, Eugen, editor, Schönbaum, Eduard, editor, and Lomax, Peter, editor
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- 1994
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21. Does Intraoperative Core Hypothermia Increase the Incidence of Surgical Wound Infections and Prolong Hospitalization?
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Kurz, A., Sessler, D. I., Lenhardt, R., Narzt, E., Huemer, G., Lackner, F., Zeisberger, Eugen, editor, Schönbaum, Eduard, editor, and Lomax, Peter, editor
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- 1994
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22. Thermoregulation and Heat Balance: General Anesthesia
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Sessler, D. I., Zeisberger, Eugen, editor, Schönbaum, Eduard, editor, and Lomax, Peter, editor
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- 1994
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23. Using the STOP-BANG questionnaire to predict hypoxaemia in patients recovering from noncardiac surgery: a prospective cohort analysis
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Khanna, A. K., Sessler, D. I., Sun, Z., Naylor, A. J., You, J., Hesler, B. D., Kurz, A., Devereaux, P. J., and Saager, L.
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- 2016
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24. Standardizing end points in perioperative trials: towards a core and extended outcome set
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Myles, P. S., Grocott, M. P. W., Boney, O., Moonesinghe, S. R., Myles, Paul, Grocott, Michael, Biccard, Bruce, Boney, Oliver, Chan, Matthew, Fleisher, Lee, Kalkman, Cor, Kurz, Andrea, Moonesinghe, Ramani, Wijeysundera, Duminda, Bartoszko, J., Beattie, W. S., Bellomo, R., Buggy, D., Cabrini, L., Canet, J., Cook, T., Cooper, D. J., Corcoran, T., Devereaux, P. J., Eckenhoff, R., Evered, L., Gan, T. J., Gin, T., Grocott, H., Haller, G., Howell, S., Jayarajah, M., Kalkman, C., Karkouti, K., Kavanagh, B., Klein, A., Landoni, G., Leslie, K., McIlroy, D. R., Mazer, D., Moller, A., Mythen, M., Neuman, M., Neuman, M., Pearse, R., Peyton, P., Prowle, J., Richards, T., Scott, D. A., Sessler, D., Shaw, A., Short, T., Shulman, M., Silbert, B., Singer, M., Sneyd, J. R., Story, D., van Dijk, D., and van Klei, W.
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- 2016
- Full Text
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25. Tunnelling of thoracic epidural catheters is associated with fewer catheter-related infections: a retrospective registry analysis
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Bomberg, H., Kubulus, C., Herberger, S., Wagenpfeil, S., Kessler, P., Steinfeldt, T., Standl, T., Gottschalk, A., Stork, J., Meissner, W., Birnbaum, J., Koch, T., Sessler, D. I., Volk, T., and Raddatz, A.
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- 2016
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26. Supplement to: Clonidine in patients undergoing noncardiac surgery.
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Devereaux, P J, Sessler, D I, and Leslie, K
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- 2014
27. Supplement to: Aspirin in patients undergoing noncardiac surgery.
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Devereaux, P J, Mrkobrada, M, and Sessler, D I
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- 2014
28. Effects of supplemental oxygen and dexamethasone on surgical site infection: a factorial randomized trial‡
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Kurz, A., Fleischmann, E., Sessler, D. I., Buggy, D. J., Apfel, C., Akça, O., Fleischmann, Edith, Erdik, Erol, Eredics, Klaus, Kabon, Barbara, Herbst, Friedrich, Kazerounian, Sara, Kugener, Andre, Marschalek, Corinna, Mikocki, Pia, Niedermayer, Monika, Obewegeser, Eva, Ratzenboeck, Ina, Rozum, Romana, Sindhuber, Sonja, Schlemitz, Katja, Schebesta, Karl, Stift, Anton, Kurz, Andrea, Sessler, Daniel I., Bala, Endrit, Chen, Samuel T., Devarajan, Jagan, Maheshwari, Ankit, Mahboobi, Ramatia, Mascha, Edward, Nagem, Hassan, Rajogopalan, Suman, Reynolds, Luke, Alvarez, Adrian, Stocchi, Luca, Doufas, Anthony G., Govinda, Raghavendra, Kasuya, Yusuke, Komatsu, Ryu, Lenhardt, Rainer, Orhan-Sungur, Mukadder, Sengupta, Papiya, Wadhwa, Anupama, Galandiuk, Susan, Buggy, Donal, Arain, Mujeeb, Burke, Siun, McGuire, Barry, Ragheb, Jackie, and Taguchi, Akikio
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- 2015
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29. Feasibility of closed-loop co-administration of propofol and remifentanil guided by the bispectral index in obese patients: a prospective cohort comparison†
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Liu, N., Lory, C., Assenzo, V., Cocard, V., Chazot, T., Le Guen, M., Sessler, D. I., Journois, D., and Fischler, M.
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- 2015
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30. The effects of Patent Blue dye on peripheral and cerebral oxyhaemoglobin saturations*
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Ishiyama, T., Kotoda, M., Asano, N., Ikemoto, K., Mitsui, K., Sato, H., Matsukawa, T., and Sessler, D. I.
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- 2015
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31. Thromboelastometry-guided intraoperative haemostatic management reduces bleeding and red cell transfusion after paediatric cardiac surgery
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Nakayama, Y., Nakajima, Y., Tanaka, K. A., Sessler, D. I., Maeda, S., Iida, J., Ogawa, S., and Mizobe, T.
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- 2015
- Full Text
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32. Consensus statement from the BJA Workshop on Cancer and Anaesthesia
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Buggy, D. J., Borgeat, A., Cata, J., Doherty, D. G., Doornebal, C. W., Forget, P., Gottumukkala, V., Gottschalk, A., Gupta, A., Gupta, K., Hales, T. G., Hemmings, H. C., Hollmann, M. W., Kurz, A., Ma, D., Parat, M. O., Sessler, D. I., Shorten, G., and Singleton, P.
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- 2015
- Full Text
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33. Design of Clinical Trials Evaluating Sedation in Critically Ill Adults Undergoing Mechanical Ventilation
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Ward, D. S., Absalom, A. R., Aitken, L. M., Balas, M. C., Brown, D. L., Burry, L., Colantuoni, E., Coursin, D., Devlin, J. W., Dexter, F., Dworkin, R. H., Egan, T. D., Elliott, D., Egerod, I., Flood, P., Fraser, G. L., Girard, T. D., Gozal, D., Hopkins, R. O., Kress, J., Maze, M., Needham, D. M., Pandharipande, P., Riker, R., Sessler, D. I., Shafer, S. L., Shehabi, Y., Spies, C., Sun, L. S., Tung, A., and Urman, R. D.
- Subjects
R1 - Abstract
Objectives: \ud Clinical trials evaluating the safety and effectiveness of sedative medication use in critically ill adults undergoing mechanical ventilation differ considerably in their methodological approach. This heterogeneity impedes the ability to compare results across studies. The Sedation Consortium on Endpoints and Procedures for Treatment, Education, and Research Recommendations convened a meeting of multidisciplinary experts to develop recommendations for key methodologic elements of sedation trials in the ICU to help guide academic and industry clinical investigators.\ud \ud Design: \ud A 2-day in-person meeting was held in Washington, DC, on March 28–29, 2019, followed by a three-round, online modified Delphi consensus process.\ud \ud Participants: \ud Thirty-six participants from academia, industry, and the Food and Drug Administration with expertise in relevant content areas, including two former ICU patients attended the in-person meeting, and the majority completed an online follow-up survey and participated in the modified Delphi process.\ud Measurements and Main\ud \ud Results: \ud The final recommendations were iteratively refined based on the survey results, participants’ reactions to those results, summaries written by panel moderators, and a review of the meeting transcripts made from audio recordings. Fifteen recommendations were developed for study design and conduct, subject enrollment, outcomes, and measurement instruments. Consensus recommendations included obtaining input from ICU survivors and/or their families, ensuring adequate training for personnel using validated instruments for assessments of sedation, pain, and delirium in the ICU environment, and the need for methodological standardization.\ud \ud Conclusions: \ud These recommendations are intended to assist researchers in the design, conduct, selection of endpoints, and reporting of clinical trials involving sedative medications and/or sedation protocols for adult ICU patients who require mechanical ventilation. These recommendations should be viewed as a starting point to improve clinical trials and help reduce methodological heterogeneity in future clinical trials.
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- 2021
34. ProBGP: Progressive Visual Analytics of Live BGP Updates
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Ulmer, A., primary, Sessler, D., additional, and Kohlhammer, J., additional
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- 2021
- Full Text
- View/download PDF
35. Systematic review and consensus definitions for the Standardized Endpoints in Perioperative Medicine (StEP) initiative: cardiovascular outcomes
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Beattie, WS, Lalu, M, Bocock, M, Feng, S, Wijeysundera, DN, Nagele, P, Fleisher, LA, Kurz, A, Biccard, B, Leslie, K, Howell, S, Landoni, G, Grocott, H, Lamy, A, Richards, T, Myles, P, Cooper, DJ, Gan, TJ, Peyton, P, Sessler, D, Tramèr, M, Cyna, A, De Oliveira, GS, Wu, C, Jensen, M, Kehlet, H, Botti, Mari, Boney, O, Haller, G, Grocott, M, Cook, T, Fleisher, L, Neuman, M, Story, D, Gruen, R, Bampoe, S, Evered, L, Scott, D, Silbert, B, van Dijk, D, Kalkman, C, Chan, M, Eckenhoff, R, Rasmussen, L, Eriksson, L, Beattie, S, Wijeysundera, D, Bartlett, RJ, McMonnies, R, Gerstl, J, Jay, M, Kishlyansky, D, Machina, M, Bobcock, M, Pearse, R, Mythen, M, Canet, J, Moller, A, Gin, T, Schultz, M, Pelosi, P, Gabreu, M, Futier, E, Creagh-Brown, B, Abbott, T, Klein, A, Corcoran, T, Dieleman, S, Diouf, E, McIlroy, D, Bellomo, R, Shaw, A, Prowle, J, Karkouti, K, Billings, J, Mazer, D, Jayarajah, M, Murphy, M, Bartoszko, J, Sneyd, R, Morris, S, George, R, Moonesinghe, R, Shulman, M, Lane-Fall, M, Nilsson, U, Stevenson, N, Cooper, J, van Klei, W, Cabrini, L, Miller, T, Pace, N, Jackson, S, Buggy, D, Short, T, Riedel, B, Gottumukkala, V, Alkhaffaf, B, Beattie, WS, Lalu, M, Bocock, M, Feng, S, Wijeysundera, DN, Nagele, P, Fleisher, LA, Kurz, A, Biccard, B, Leslie, K, Howell, S, Landoni, G, Grocott, H, Lamy, A, Richards, T, Myles, P, Cooper, DJ, Gan, TJ, Peyton, P, Sessler, D, Tramèr, M, Cyna, A, De Oliveira, GS, Wu, C, Jensen, M, Kehlet, H, Botti, Mari, Boney, O, Haller, G, Grocott, M, Cook, T, Fleisher, L, Neuman, M, Story, D, Gruen, R, Bampoe, S, Evered, L, Scott, D, Silbert, B, van Dijk, D, Kalkman, C, Chan, M, Eckenhoff, R, Rasmussen, L, Eriksson, L, Beattie, S, Wijeysundera, D, Bartlett, RJ, McMonnies, R, Gerstl, J, Jay, M, Kishlyansky, D, Machina, M, Bobcock, M, Pearse, R, Mythen, M, Canet, J, Moller, A, Gin, T, Schultz, M, Pelosi, P, Gabreu, M, Futier, E, Creagh-Brown, B, Abbott, T, Klein, A, Corcoran, T, Dieleman, S, Diouf, E, McIlroy, D, Bellomo, R, Shaw, A, Prowle, J, Karkouti, K, Billings, J, Mazer, D, Jayarajah, M, Murphy, M, Bartoszko, J, Sneyd, R, Morris, S, George, R, Moonesinghe, R, Shulman, M, Lane-Fall, M, Nilsson, U, Stevenson, N, Cooper, J, van Klei, W, Cabrini, L, Miller, T, Pace, N, Jackson, S, Buggy, D, Short, T, Riedel, B, Gottumukkala, V, and Alkhaffaf, B
- Published
- 2021
36. Association between fibromyalgia and adverse perioperative outcomes
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Hesler, B. D., Dalton, J. E., Singh, H., Chahar, P., Saager, L., Sessler, D. I., and Turan, A.
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- 2014
- Full Text
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37. Association between neuraxial analgesia, cancer progression, and mortality after radical prostatectomy: a large, retrospective matched cohort study
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Scavonetto, F., Yeoh, T. Y., Umbreit, E. C., Weingarten, T. N., Gettman, M. T., Frank, I., Boorjian, S. A., Karnes, R. J., Schroeder, D. R., Rangel, L. J., Hanson, A. C., Hofer, R. E., Sessler, D. I., and Sprung, J.
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- 2014
- Full Text
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38. Nitrous oxide does not produce a clinically important sparing effect during closed-loop delivered propofol-remifentanil anaesthesia guided by the bispectral index: a randomized multicentre study†,‡
- Author
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Liu, N., Le Guen, M., Boichut, N., Genty, A., Hérail, T., Schmartz, D., Khefif, G., Landais, A., Bussac, J. J., Charmeau, A., Baars, J., Rehberg, B., Tricoche, S., Chazot, T., Sessler, D. I., and Fischler, M.
- Published
- 2014
- Full Text
- View/download PDF
39. Big Data – and its contributions to peri-operative medicine
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Sessler, D. I.
- Published
- 2014
- Full Text
- View/download PDF
40. The analgesic efficiency of combined pregabalin and ketamine for total hip arthroplasty: a randomised, double-blind, controlled study
- Author
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Martinez, V., Cymerman, A., Ben Ammar, S., Fiaud, J. F., Rapon, C., Poindessous, F., Judet, T., Chauvin, M., Bouhassira, D., Sessler, D., Mazoit, X., and Fletcher, D.
- Published
- 2014
- Full Text
- View/download PDF
41. Hydroxyethyl starch on kidney and haemostatic function in cardiac surgical patients: is a non‐inferiority study design appropriate for this setting? A reply
- Author
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Duncan, A. E., primary and Sessler, D. I., additional
- Published
- 2021
- Full Text
- View/download PDF
42. Hypercapnia and surgical site infection: a randomized trial†
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Akça, O., Kurz, A., Fleischmann, E., Buggy, D., Herbst, F., Stocchi, L., Galandiuk, S., Iscoe, S., Fisher, J., Apfel, C. C., and Sessler, D. I.
- Published
- 2013
- Full Text
- View/download PDF
43. Dexamethasone, light anaesthesia, and tight glucose control (DeLiT) randomized controlled trial†
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Abdelmalak, B. B., Bonilla, A., Mascha, E. J., Maheshwari, A., Wilson Tang, W. H., You, J., Ramachandran, M., Kirkova, Y., Clair, D., Walsh, R. M., Kurz, A., and Sessler, D. I.
- Published
- 2013
- Full Text
- View/download PDF
44. Inflammatory response, immunosuppression, and cancer recurrence after perioperative blood transfusions
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Cata, J. P., Wang, H., Gottumukkala, V., Reuben, J., and Sessler, D. I.
- Published
- 2013
- Full Text
- View/download PDF
45. Intraoperative tissue oxygenation and postoperative outcomes after major non-cardiac surgery: an observational study†
- Author
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Abdelmalak, B. B., Cata, J. P., Bonilla, A., You, J., Kopyeva, T., Vogel, J. D., Campbell, S., and Sessler, D. I.
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- 2013
- Full Text
- View/download PDF
46. Lidocaine/tetracaine patch (Rapydan) for topical anaesthesia before arterial access: a double-blind, randomized trial
- Author
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Ruetzler, K., Sima, B., Mayer, L., Golescu, A., Dunkler, D., Jaeger, W., Hoeferl, M., You, J., Sessler, D. I., Grubhofer, G., and Hutschala, D.
- Published
- 2012
- Full Text
- View/download PDF
47. Ventilation with low tidal volumes during upper abdominal surgery does not improve postoperative lung function
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Treschan, T. A., Kaisers, W., Schaefer, M. S., Bastin, B., Schmalz, U., Wania, V., Eisenberger, C. F., Saleh, A., Weiss, M., Schmitz, A., Kienbaum, P., Sessler, D. I., Pannen, B., and Beiderlinden, M.
- Published
- 2012
- Full Text
- View/download PDF
48. Association between preoperative statin therapy and postoperative change in glomerular filtration rate in endovascular aortic surgery
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Argalious, M. Y., Dalton, J. E., Cywinski, J. B., Seif, J., Abdelmalak, M., and Sessler, D. I.
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- 2012
- Full Text
- View/download PDF
49. Effect of dexamethasone on the duration of interscalene nerve blocks with ropivacaine or bupivacaine
- Author
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Cummings, K. C., III, Napierkowski, D. E., Parra-Sanchez, I., Kurz, A., Dalton, J. E., Brems, J. J., and Sessler, D. I.
- Published
- 2011
- Full Text
- View/download PDF
50. Intra-operative rewarming with Hot Dog® resistive heating and forced-air heating: a trial of lower-body warming
- Author
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Röder, G., Sessler, D. I., Roth, G., Schopper, C., Mascha, E. J., and Plattner, O.
- Published
- 2011
- Full Text
- View/download PDF
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