1. Diagnostic value of a negative single complete compression ultrasound of the lower limbs to exclude the diagnosis of deep venous thrombosis in pregnant or postpartum women: A retrospective hospital-based study
- Author
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M. Collet, Caroline Bohec, Karine Lacut, Marc Philip Righini, Jean-Claude Vergos, Anne-Marije Prins, Pierre Germain, Emmanuel Oger, Raymond Kaczmarek, Grégoire Le Gal, Bruno Guias, Luc Bressollette, Dominique Mottier, Groupe d'Etude de la Thrombose de Bretagne Occidentale (GETBO), Université de Brest (UBO)-Institut Brestois Santé Agro Matière (IBSAM), Université de Brest (UBO)-Université de Brest (UBO), Centre d'Investigation Clinique (CIC - Brest), Université de Brest (UBO)-Institut National de la Santé et de la Recherche Médicale (INSERM), Département de Médecine Interne et Pneumologie [Brest] (DMIP - Brest), Centre Hospitalier Régional Universitaire de Brest (CHRU Brest), Service d'angiologie et d'hémostase (MR), Hôpital Universitaire de Genève, Service de Gynécologie (CHIC - Gynécologie), CHIC Quimper, Service de Radiologie (CHIC - Radiologie), CHIC, Service de Gynécologie (CHPM - Gynécologie), CHPM - Morlaix, and Service de Gynécologie-Obstétrique (BREST - Gynéco-Obs)
- Subjects
Adult ,medicine.medical_specialty ,Adolescent ,Pregnancy Complications, Cardiovascular ,MESH: Lower Extremity ,MESH: Pregnancy Complications, Cardiovascular ,030204 cardiovascular system & hematology ,MESH: Postpartum Period ,03 medical and health sciences ,MESH: Pregnancy ,0302 clinical medicine ,Predictive Value of Tests ,Pregnancy ,medicine ,Humans ,030212 general & internal medicine ,Risk factor ,Retrospective Studies ,Ultrasonography ,MESH: Adolescent ,Venous Thrombosis ,MESH: Humans ,Vascular disease ,business.industry ,Obstetrics ,Medical record ,Postpartum Period ,MESH: Adult ,MESH: Retrospective Studies ,Retrospective cohort study ,MESH: Follow-Up Studies ,Hematology ,medicine.disease ,MESH: Predictive Value of Tests ,3. Good health ,Surgery ,Venous thrombosis ,Lower Extremity ,Embolism ,Predictive value of tests ,MESH: Venous Thrombosis ,Female ,business ,MESH: Female ,[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology ,Postpartum period ,Follow-Up Studies - Abstract
Objective We aimed at determining whether a negative single complete compression ultrasonography (CUS) of the lower limbs veins is a safe and accurate diagnostic method to rule out the diagnosis of deep venous thrombosis in pregnant and early postpartum women. Design Hospital-based retrospective study. Setting The gynaecology and vascular ultrasound units of three general hospitals in western France. Patients We identified from the hospitals databases all pregnant or up to three months postpartum women who underwent CUS for a suspicion of deep venous thrombosis between January 2002 and December 2004. Methods Questionnaires were sent to all women with a negative CUS. Their medical records were also checked. Main outcome measures We assessed the three-month thromboembolic risk and its 95% percent confidence interval in women left untreated on the basis of a negative single complete CUS of the lower limbs. Results During the study period, 162 pregnant or postpartum women underwent CUS for a suspicion of deep venous thrombosis. It was positive in 44 (27%). The 118 women who had a negative CUS were sent the questionnaire. Information about the three-month follow-up was found for 107 patients (91%). None of them experienced a thromboembolic event during follow-up: 0.0% (95% CI: 0.0–3.6). Conclusions Single complete CUS of lower limbs veins appears to be a safe method to rule out the diagnosis of deep venous thrombosis in pregnant or early postpartum women. This has to be confirmed by a prospective management study with a formal follow-up.
- Published
- 2006
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