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1. Metallothionein-3 is a multifunctional driver that modulates the development of sorafenib-resistant phenotype in hepatocellular carcinoma cells

2. The lipopolysaccharide-TLR4 axis regulates hepatic glutaminase 1 expression promoting liver ammonia build-up as steatotic liver disease progresses to steatohepatitis

3. SUMOylation controls Hu antigen R posttranscriptional activity in liver cancer

4. Anti-miR-873-5p improves alcohol-related liver disease by enhancing hepatic deacetylation via SIRT1

5. Neddylation of phosphoenolpyruvate carboxykinase 1 controls glucose metabolism

6. Hepatic levels of S-adenosylmethionine regulate the adaptive response to fasting

7. Arachidyl amido cholanoic acid improves liver glucose and lipid homeostasis in nonalcoholic steatohepatitis via AMPK and mTOR regulation

8. Targeting Hepatic Glutaminase 1 Ameliorates Non-alcoholic Steatohepatitis by Restoring Very-Low-Density Lipoprotein Triglyceride Assembly

9. miR-873-5p targets mitochondrial GNMT-Complex II interface contributing to non-alcoholic fatty liver disease

10. FRI-153 High prevalence of steatotic liver disease and systemic inflammation in hereditary fructose intolerance (HFI) patients independent of age, BMI and the presence of metabolic syndrome

11. Neddylation inhibition ameliorates steatosis in NAFLD by boosting hepatic fatty acid oxidation via the DEPTOR-mTOR axis

12. Boosting mitochondria activity by silencing MCJ overcomes cholestasis-induced liver injury

13. Pediatric liver cancer: Hepatoblastoma and Neddylation post-translational modification

14. Silencing CNNM4 in cholangiocarcinoma inhibits tumoral progression by means of non-canonical ferroptosis

15. Metabolic rewiring by increased mitochondrial respiration drives immunosuppression in liver cancer

16. Neddylation inhibition recovers drug-induced liver injury through the stabilization of Tamm41

17. Magnesium modulation by CNNM4 silencing in DIAMOND mice via GalNAc-siRNA therapy: a new and effective therapeutic approach against MAFLD

18. MAP17 promotes metastasis in hepatocellular carcinoma by modulating the epithelial-mesenchymal-amoeboid transition

19. Targeting liver glutaminase 1 modulates hepatic ammonia in experimental Non-Alcoholic Steatohepatitis

20. Magnesium accumulation by CNNM4 GalNAc-siRNA mediated silencing reduces cholestasis-associated liver fibrosis

21. Targeting NAE1-mediated protein hyper-NEDDylation halts cholangiocarcinogenesis and impacts on tumour-stroma crosstalk in experimental models

22. Targeting cyclin M4 as a new therapeutical approach to treat alcoholic liver disease

23. FRI-466-YI Implications and therapeutic potential of neddylation for pediatric liver cancer: hepatoblastoma

25. SAT-244 - Silencing CNNM4 in cholangiocarcinoma inhibits tumoral progression by means of non-canonical ferroptosis

26. SAT-247 - Pediatric liver cancer: Hepatoblastoma and Neddylation post-translational modification

27. SAT-221 - Metabolic rewiring by increased mitochondrial respiration drives immunosuppression in liver cancer

28. FRI-399 - Neddylation inhibition recovers drug-induced liver injury through the stabilization of Tamm41

29. NEDD8 specific protease 1 (NEDP1) as a tumor suppressor in hepatocellular carcinoma

30. MCJ deficiency results in gut barrier dysfunction and macrophage-elicited inflammation following ethanol consumption, facilitating alcoholic endotoxemia

31. Novel therapy with anti-miR-873-5p at late stages of acetaminophen overdose

32. miR-873-5p targets mitochondrial GNMT-Complex II interface contributing to non-alcoholic fatty liver disease

33. miR-873-5p targets mitochondrialGNMT-Complex II interface contributing tonon-alcoholic fatty liver disease

35. FRI-353-Metabolic implications of methionine adenosyltransferase 1A depletion during fasting

36. FRI-343-NEDDylation inhibition as a new potential therapy of non-alcoholic fatty liver disease

37. FRI-294-Mitochondrial GNMT-complex II is recovered by miR-873-5p targeting in NAFLD

38. PS-034-MCJ: A therapeutic target in hepatic ischemia and reperfusion injury

39. THU-477-Sumoylation/acetylation drives forward oncogenic role of LKB1 in Liver

40. FRI-094-Targeting NEDDylation protects liver from acute drug-induced damage

42. SUMOylation regulates LKB1 localization and its oncogenic activity in liver cancer

44. THU185 - Novel therapy with anti-miR-873-5p at late stages of acetaminophen overdose.

45. AS110 - MCJ deficiency results in gut barrier dysfunction and macrophage-elicited inflammation following ethanol consumption, facilitating alcoholic endotoxemia.

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