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Background Alcohol drinking during pregnancy has harmful consequences. Warnings displayed on alcohol bottles are an effective measure to inform people about these risks and have been put in place in France. However, the alcohol industry (AI) resisted this measure when it was introduced in 2007 and during an expansion project in 2018. This study aims to identify arguments used by the AI against warnings targeting pregnant women. Methods A documentary method was used to analyse these arguments disseminated by the AI and its partners (elected representatives of wine-producing regions, etc.) in the French mainstream press (the national, regional and specialised press) from 2000 to 2020 through the Europresse documentary database. A quantitative analysis (number and evolution of press articles, mapping of the actors of AI who expressed themselves) and an inductive thematic content analysis (analytical framework of the arguments identified) using NVivo Software were carried out. Results Among the 85 articles included in this study, a majority of the arguments used by the AI are against this measure. It argues that this measure (1) is a questionable measure because ineffective in changing behaviours, (2) will have counterproductive effects (on women and on the economy); and (3) there are other preferred alternatives than warnings (targeted prevention programs, etc.). A minority is nevertheless in favour of this measure. Among the actors who expressed themselves, a large majority comes from the winegrowing sector. Conclusions The analysis of these arguments will add new insights about AI lobbying against warnings, by analyzing the arguments over a 20 years period covering a failure and a success of industry lobbying. It will also be useful for public health advocacy to better counter this lobbying influence and these arguments, which are not necessarily evidence based. Key messages • Warnings displayed on alcohol bottles are an effective measure which is challenged by the alcohol industry. • Analysing the arguments disseminated by the alcohol industry is useful for public health advocacy in order to counter them.

Treball de fi de grau en Traducció i Interpretació Translating poetry is something very few people do due to its difficulty, especially when the languages involved come from different origins and do not share tradition and rules. This is the main motivation of this project: to translate and work on a made-for-the- occasion anthology of the poet Rainer Maria Rilke's works of art, which contains five poems (three in German and two in French). Therefore, the aim of this project is to expose my translations into Catalan of those five sho1t poems, in which I try to solve the main problems that such different languages set up during translation, and contextualise the reader by providing them a brief biography of R. M. Rilke, an essay about the most common problems of translating poetry and also some published translations of the same poems. In order to do so, I selected a different methodology for each poem with the goal of approaching the translations in the most appropriate way possible depending on its characteristics: seeking rhyme, metrics, figures of speech, meaning or a reasonable combination of some. The results of the work are obtaining a faithful translation for each original poem, despite the huge differences among the languages involved. Once finished this work, I came to realise that the author used different writings depending on the language he used to create, and after analysing and commenting both original and translated poems, I can state that I have accomplished all my objectives, for I have achieved each translation satisfactorily despite the difficulty involved.

The similarity of stromal-like Wilms tumor (str-WT) cells with mesenchymal stem cells (MSC), suggests their relevant role in the interplay with immune cells in the tumor microenvironment. We investigated the interaction between str-WT cells and NK cells. We observed that str-WT cells expressed some major ligands for activating and inhibitory NK cell receptors. Moreover, they expressed inhibitory checkpoint molecules involved in the negative regulation of anti-tumor immune response. The analysis of the interaction between str-WT cells and NK lymphocytes revealed that activated NK cells could efficiently degranulate upon interaction with str-WT cells. On the other hand, str-WT cells could exert potent inhibitory effects on cytokine-induced activation of NK cell proliferation and phenotype, which were mediated by the production of IDO and PGE2 inhibitory factors. Our data provide insight into the molecular interactions between str-WT cells and NK lymphocytes that may result in different outcomes possibly occurring in the WT microenvironment.