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3. Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013

Author

Collaborators, Global Burden of Disease Study 2013, Vos, Theo, Barber, Ryan M, Bell, Brad, Bertozzi-Villa, Amelia, Biryukov, Stan, Bolliger, Ian, Charlson, Fiona, Davis, Adrian, Degenhardt, Louisa, Dicker, Daniel, Duan, Leilei, Erskine, Holly, Feigin, Valery L, Ferrari, Alize J, Fitzmaurice, Christina, Fleming, Thomas, Graetz, Nicholas, Guinovart, Caterina, Haagsma, Juanita, Hansen, Gillian M, Hanson, Sarah Wulf, Heuton, Kyle R, Higashi, Hideki, Kassebaum, Nicholas, Kyu, Hmwe, Laurie, Evan, Liang, Xiofeng, Lofgren, Katherine, Lozano, Rafael, MacIntyre, Michael F, Moradi-Lakeh, Maziar, Naghavi, Mohsen, Nguyen, Grant, Odell, Shaun, Ortblad, Katrina, Roberts, David Allen, Roth, Gregory A, Sandar, Logan, Serina, Peter T, Stanaway, Jeffrey D, Steiner, Caitlyn, Thomas, Bernadette, Vollset, Stein Emil, Whiteford, Harvey, Wolock, Timothy M, Ye, Pengpeng, Zhou, Maigeng, Ãvila, Marco A, Aasvang, Gunn Marit, Abbafati, Cristiana, Ozgoren, Ayse Abbasoglu, Abd-Allah, Foad, Aziz, Muna I Abdel, Abera, Semaw F, Aboyans, Victor, Abraham, Jerry P, Abraham, Biju, Abubakar, Ibrahim, Abu-Raddad, Laith J, Abu-Rmeileh, Niveen ME, Aburto, Tania C, Achoki, Tom, Ackerman, Ilana N, Adelekan, Ademola, Ademi, Zanfina, Adou, Arsène K, Adsuar, Josef C, Arnlov, Johan, Agardh, Emilie E, Khabouri, Mazin J Al, Alam, Sayed Saidul, Alasfoor, Deena, Albittar, Mohammed I, Alegretti, Miguel A, Aleman, Alicia V, Alemu, Zewdie A, Alfonso-Cristancho, Rafael, Alhabib, Samia, Ali, Raghib, Alla, Francois, Allebeck, Peter, Allen, Peter J, AlMazroa, Mohammad AbdulAziz, Alsharif, Ubai, Alvarez, Elena, Alvis-Guzman, Nelson, Ameli, Omid, Amini, Heresh, Ammar, Walid, Anderson, Benjamin O, Anderson, H Ross, Antonio, Carl Abelardo T, Anwari, Palwasha, Apfel, Henry, Arsenijevic, Valentain S Arsic, Artaman, Al, Asghar, Rana J, Assadi, Reza, and Atkins, Lydia S

Subjects
Burden of Illness, Infectious Diseases, Brain Disorders, Pain Research, Mental Health, 2.4 Surveillance and distribution, Aetiology, 2.1 Biological and endogenous factors, 2.2 Factors relating to the physical environment, Good Health and Well Being, Acute Disease, Adolescent, Adult, Age Distribution, Aged, Aged, 80 and over, Child, Child, Preschool, Chronic Disease, Cost of Illness, Developed Countries, Developing Countries, Disabled Persons, Female, Global Health, Humans, Incidence, Infant, Infant, Newborn, Male, Middle Aged, Neglected Diseases, Prevalence, Residence Characteristics, Sex Distribution, Wounds and Injuries, Young Adult, Global Burden of Disease Study 2013 Collaborators, Medical and Health Sciences, General & Internal Medicine
Abstract

BackgroundUp-to-date evidence about levels and trends in disease and injury incidence, prevalence, and years lived with disability (YLDs) is an essential input into global, regional, and national health policies. In the Global Burden of Disease Study 2013 (GBD 2013), we estimated these quantities for acute and chronic diseases and injuries for 188 countries between 1990 and 2013.MethodsEstimates were calculated for disease and injury incidence, prevalence, and YLDs using GBD 2010 methods with some important refinements. Results for incidence of acute disorders and prevalence of chronic disorders are new additions to the analysis. Key improvements include expansion to the cause and sequelae list, updated systematic reviews, use of detailed injury codes, improvements to the Bayesian meta-regression method (DisMod-MR), and use of severity splits for various causes. An index of data representativeness, showing data availability, was calculated for each cause and impairment during three periods globally and at the country level for 2013. In total, 35 620 distinct sources of data were used and documented to calculated estimates for 301 diseases and injuries and 2337 sequelae. The comorbidity simulation provides estimates for the number of sequelae, concurrently, by individuals by country, year, age, and sex. Disability weights were updated with the addition of new population-based survey data from four countries.FindingsDisease and injury were highly prevalent; only a small fraction of individuals had no sequelae. Comorbidity rose substantially with age and in absolute terms from 1990 to 2013. Incidence of acute sequelae were predominantly infectious diseases and short-term injuries, with over 2 billion cases of upper respiratory infections and diarrhoeal disease episodes in 2013, with the notable exception of tooth pain due to permanent caries with more than 200 million incident cases in 2013. Conversely, leading chronic sequelae were largely attributable to non-communicable diseases, with prevalence estimates for asymptomatic permanent caries and tension-type headache of 2·4 billion and 1·6 billion, respectively. The distribution of the number of sequelae in populations varied widely across regions, with an expected relation between age and disease prevalence. YLDs for both sexes increased from 537·6 million in 1990 to 764·8 million in 2013 due to population growth and ageing, whereas the age-standardised rate decreased little from 114·87 per 1000 people to 110·31 per 1000 people between 1990 and 2013. Leading causes of YLDs included low back pain and major depressive disorder among the top ten causes of YLDs in every country. YLD rates per person, by major cause groups, indicated the main drivers of increases were due to musculoskeletal, mental, and substance use disorders, neurological disorders, and chronic respiratory diseases; however HIV/AIDS was a notable driver of increasing YLDs in sub-Saharan Africa. Also, the proportion of disability-adjusted life years due to YLDs increased globally from 21·1% in 1990 to 31·2% in 2013.InterpretationAgeing of the world's population is leading to a substantial increase in the numbers of individuals with sequelae of diseases and injuries. Rates of YLDs are declining much more slowly than mortality rates. The non-fatal dimensions of disease and injury will require more and more attention from health systems. The transition to non-fatal outcomes as the dominant source of burden of disease is occurring rapidly outside of sub-Saharan Africa. Our results can guide future health initiatives through examination of epidemiological trends and a better understanding of variation across countries.FundingBill & Melinda Gates Foundation.

Published
2015

4. Emergency Department--Based Physical Function Measures for Falls in Older Adults and Outcomes: A Secondary Analysis of GAPcare.

Author

Strauss, Daniel H., Davoodi, Natalie M., Resnik, Linda J., Keene, Sarah, Serina, Peter T., and Goldberg, Elizabeth M.

Subjects
RISK assessment, SECONDARY analysis, DATA analysis, HOSPITAL emergency services, EVALUATION of medical care, DESCRIPTIVE statistics, CHI-squared test, GERIATRIC assessment, STATISTICS, DATA analysis software, ACCIDENTAL falls, OLD age
Abstract

Background and Purpose: Falls are the leading reason for Injury-related emergency department (ED) visits for older adults. The Geriatric Acute and Post-acute Fall Prevention Intervention (GAPcare), an in-ED intervention combining a medication therapy management session delivered by a pharmacist and a fall risk assessment and plan by a physical therapist, reduced ED revisits at 6 months among older adults presenting after a fall. Our objective was to evaluate the relationship between measures of function obtained in the ED and clinical outcomes. Methods: This was a secondary analysis of data from GAPcare, a randomized controlled trial conducted from January 2018 to October 2019 at 2 urban academic EDs. Standardized measures of function (Timed Up and Go [TUG] test, Barthel Activity of Daily Living Index [ADL], Activity Measure for Post Acute Care [AM-PAC] 6 clicks) were collected at the ED index visit. We performed a descriptive analysis and hypothesis testing (chi square test and analysis of variance) to assess the relationship of functional measures with outcomes (ED disposition, ED revisits for falls, and place of residence at 6 months). Emergency department disposition status refers to dis- charge location immediately after the ED evaluation is complete (eg, hospital admission, original residence, skilled nursing facility). Results and Discussion: Among 110 participants, 55 were randomized to the GAPcare intervention and 55 received usual care. Of those randomized to the intervention, 46 received physical therapy consultation. Median age was 81 years; participants were predominantly women (67%) and White (94%). Seventy-three (66%) were discharged to their original residence, 14 (13%) were discharged to a skilled nursing facility and 22 (20%) were admitted. There was no difference in ED disposition status by index visit Barthel ADLs (P = .371); however, TUG times were faster (P = .016), and AM-PAC 6 clicks score was higher among participants dis-charged to their original residence (P ≤ .001). Participants with slower TUG times at the index ED visit were more likely to reside in nursing homes by six months (P = .002), while Barthel ADL and AM-PAC 6 clicks did not differ between those residing at home and other settings. Conclusions: Measures of function collected at the index ED visit, such as the AM-PAC 6 clicks and TUG time, may be helpful at predicting clinical outcomes for older adults presenting for a fall. Based on our study findings, we suggest a novel workflow to guide the use of these clinical measures for ED patients with falls. [ABSTRACT FROM AUTHOR]

Published
2024
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6. Emergency department resource utilization among nursing home residents, a National Cross-Sectional Study.

Author

Serina, Peter T., Xu, Chuyun, Baird, Janette, Wang, Henry E., Donnelly, John P., Amanullah, Siraj, and Lo, Alexander X.

Abstract

Persons 65 years and older (older persons), particularly residents of nursing homes (NHs), disproportionately access the emergency department (ED) and utilize more medical resources. The goal of this study is to provide a contemporary description of healthcare utilization patterns and disposition decisions for United States (US) NH residents presenting to EDs. Older persons presenting to EDs in the US were identified in the National Hospital Ambulatory Medical Care Survey (NHAMCS) 2017, 2018 and 2019 datasets. We examined demographic, clinical, and resource use characteristics and outcomes. After survey weighting, we compared the frequency of different imaging, medications, clinical interventions, and outcomes in the ED between NH residents and those residing outside NHs. From 2017 to 2019, older persons made 24,441,285 annual visits to the ED, comprising 17.5% of all visits. Among these, 1,579,916 visits (6.5%) were by NH residents. Compared with non-NH residents, NH residents were older (mean age: 81.2 [95%CI 81.5–82.9] vs 76.1 [95%CI 75.8–76.4]), underwent more imaging (82.8% [95%CI 79.5–86.1] vs 71.6% [95%CI 69.9–73.3]), were administered fewer potentially inappropriate medications (PIMs) in the ED or upon discharge (9.5% [95%CI 6.2–2.7] vs 17.1% [95%CI 15.8–18.4]), and had a higher proportion of visits resulting in hospital admission (44.1% [95%CI 38.2–49.9] vs 26.0% [95%CI 23.3, 28.7]). Older NH residents presenting to the ED use more resources and are more likely to be hospitalized compared to older persons residing outside NHs. The resource-intensive nature of these visits highlights the importance of targeted, multi-disciplinary interventions that optimize ED care for this population. [ABSTRACT FROM AUTHOR]

Published
2024
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8. Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990–2013: quantifying the epidemiological transition

Author

Murray, Christopher J L, Barber, Ryan M, Foreman, Kyle J, Ozgoren, Ayse Abbasoglu, Abd-Allah, Foad, Abera, Semaw F, Aboyans, Victor, Abraham, Jerry P, Abubakar, Ibrahim, Abu-Raddad, Laith J, Abu-Rmeileh, Niveen M, Achoki, Tom, Ackerman, Ilana N, Ademi, Zanfina, Adou, Arsène K, Adsuar, José C, Afshin, Ashkan, Agardh, Emilie E, Alam, Sayed Saidul, Alasfoor, Deena, Albittar, Mohammed I, Alegretti, Miguel A, Alemu, Zewdie A, Alfonso-Cristancho, Rafael, Alhabib, Samia, Ali, Raghib, Alla, François, Allebeck, Peter, Almazroa, Mohammad A, Alsharif, Ubai, Alvarez, Elena, Alvis-Guzman, Nelson, Amare, Azmeraw T, Ameh, Emmanuel A, Amini, Heresh, Ammar, Walid, Anderson, H Ross, Anderson, Benjamin O, Antonio, Carl Abelardo T, Anwari, Palwasha, Arnlöv, Johan, Arsenijevic, Valentina S Arsic, Artaman, Al, Asghar, Rana J, Assadi, Reza, Atkins, Lydia S, Avila, Marco A, Awuah, Baffour, Bachman, Victoria F, Badawi, Alaa, Bahit, Maria C, Balakrishnan, Kalpana, Banerjee, Amitava, Barker-Collo, Suzanne L, Barquera, Simon, Barregard, Lars, Barrero, Lope H, Basu, Arindam, Basu, Sanjay, Basulaiman, Mohammed O, Beardsley, Justin, Bedi, Neeraj, Beghi, Ettore, Bekele, Tolesa, Bell, Michelle L, Benjet, Corina, Bennett, Derrick A, Bensenor, Isabela M, Benzian, Habib, Bernabé, Eduardo, Bertozzi-Villa, Amelia, Beyene, Tariku J, Bhala, Neeraj, Bhalla, Ashish, Bhutta, Zulfiqar A, Bienhoff, Kelly, Bikbov, Boris, Biryukov, Stan, Blore, Jed D, Blosser, Christopher D, Blyth, Fiona M, Bohensky, Megan A, Bolliger, Ian W, Başara, Berrak Bora, Bornstein, Natan M, Bose, Dipan, Boufous, Soufiane, Bourne, Rupert R A, Boyers, Lindsay N, Brainin, Michael, Brayne, Carol E, Brazinova, Alexandra, Breitborde, Nicholas J K, Brenner, Hermann, Briggs, Adam D, Brooks, Peter M, Brown, Jonathan C, Brugha, Traolach S, Buchbinder, Rachelle, Buckle, Geoffrey C, Budke, Christine M, Bulchis, Anne, Bulloch, Andrew G, Campos-Nonato, Ismael R, Carabin, Hélène, Carapetis, Jonathan R, Cárdenas, Rosario, Carpenter, David O, Caso, Valeria, Castañeda-Orjuela, Carlos A, Castro, Ruben E, Catalá-López, Ferrán, Cavalleri, Fiorella, Çavlin, Alanur, Chadha, Vineet K, Chang, Jung-Chen, Charlson, Fiona J, Chen, Honglei, Chen, Wanqing, Chiang, Peggy P, Chimed-Ochir, Odgerel, Chowdhury, Rajiv, Christensen, Hanne, Christophi, Costas A, Cirillo, Massimo, Coates, Matthew M, Coffeng, Luc E, Coggeshall, Megan S, Colistro, Valentina, Colquhoun, Samantha M, Cooke, Graham S, Cooper, Cyrus, Cooper, Leslie T, Coppola, Luis M, Cortinovis, Monica, Criqui, Michael H, Crump, John A, Cuevas-Nasu, Lucia, Danawi, Hadi, Dandona, Lalit, Dandona, Rakhi, Dansereau, Emily, Dargan, Paul I, Davey, Gail, Davis, Adrian, Davitoiu, Dragos V, Dayama, Anand, De Leo, Diego, Degenhardt, Louisa, Del Pozo-Cruz, Borja, Dellavalle, Robert P, Deribe, Kebede, Derrett, Sarah, Jarlais, Don C Des, Dessalegn, Muluken, Dharmaratne, Samath D, Dherani, Mukesh K, Diaz-Torné, Cesar, Dicker, Daniel, Ding, Eric L, Dokova, Klara, Dorsey, E Ray, Driscoll, Tim R, Duan, Leilei, Duber, Herbert C, Ebel, Beth E, Edmond, Karen M, Elshrek, Yousef M, Endres, Matthias, Ermakov, Sergey P, Erskine, Holly E, Eshrati, Babak, Esteghamati, Alireza, Estep, Kara, Faraon, Emerito Jose A, Farzadfar, Farshad, Fay, Derek F, Feigin, Valery L, Felson, David T, Fereshtehnejad, Seyed-Mohammad, Fernandes, Jefferson G, Ferrari, Alize J, Fitzmaurice, Christina, Flaxman, Abraham D, Fleming, Thomas D, Foigt, Nataliya, Forouzanfar, Mohammad H, Fowkes, F Gerry R, Paleo, Urbano Fra., Franklin, Richard C, Fürst, Thomas, Gabbe, Belinda, Gaffikin, Lynne, Gankpé, Fortuné G, Geleijnse, Johanna M, Gessner, Bradford D, Gething, Peter, Gibney, Katherine B, Giroud, Maurice, Giussani, Giorgia, Dantes, Hector Gomez, Gona, Philimon, González-Medina, Diego, Gosselin, Richard A, Gotay, Carolyn C, Goto, Atsushi, Gouda, Hebe N, Graetz, Nicholas, Gugnani, Harish C, Gupta, Rahul, Gupta, Rajeev, Gutiérrez, Reyna A, Haagsma, Juanita, Hafezi-Nejad, Nima, Hagan, Holly, Halasa, Yara A, Hamadeh, Randah R, Hamavid, Hannah, Hammami, Mouhanad, Hancock, Jamie, Hankey, Graeme J, Hansen, Gillian M, Hao, Yuantao, Harb, Hilda L, Haro, Josep Maria, Havmoeller, Rasmus, Hay, Simon I, Hay, Roderick J, Heredia-Pi, Ileana B, Heuton, Kyle R, Heydarpour, Pouria, Higashi, Hideki, Hijar, Martha, Hoek, Hans W, Hoffman, Howard J, Hosgood, H Dean, Hossain, Mazeda, Hotez, Peter J, Hoy, Damian G, Hsairi, Mohamed, Hu, Guoqing, Huang, Cheng, Huang, John J, Husseini, Abdullatif, Huynh, Chantal, Iannarone, Marissa L, Iburg, Kim M, Innos, Kaire, Inoue, Manami, Islami, Farhad, Jacobsen, Kathryn H, Jarvis, Deborah L, Jassal, Simerjot K, Jee, Sun Ha, Jeemon, Panniyammakal, Jensen, Paul N, Jha, Vivekanand, Jiang, Guohong, Jiang, Ying, Jonas, Jost B, Juel, Knud, Kan, Haidong, Karch, André, Karema, Corine K, Karimkhani, Chante, Karthikeyan, Ganesan, Kassebaum, Nicholas J, Kaul, Anil, Kawakami, Norito, Kazanjan, Konstantin, Kemp, Andrew H, Kengne, Andre P, Keren, Andre, Khader, Yousef S, Khalifa, Shams Eldin A, Khan, Ejaz A, Khan, Gulfaraz, Khang, Young-Ho, Kieling, Christian, Kim, Daniel, Kim, Sungroul, Kim, Yunjin, Kinfu, Yohannes, Kinge, Jonas M, Kivipelto, Miia, Knibbs, Luke D, Knudsen, Ann Kristin, Kokubo, Yoshihiro, Kosen, Soewarta, Krishnaswami, Sanjay, Defo, Barthelemy Kuate, Bicer, Burcu Kucuk, Kuipers, Ernst J, Kulkarni, Chanda, Kulkarni, Veena S, Kumar, G Anil, Kyu, Hmwe H, Lai, Taavi, Lalloo, Ratilal, Lallukka, Tea, Lam, Hilton, Lan, Qing, Lansingh, Van C, Larsson, Anders, Lawrynowicz, Alicia E B, Leasher, Janet L, Leigh, James, Leung, Ricky, Levitz, Carly E, Li, Bin, Li, Yichong, Li, Yongmei, Lim, Stephen S, Lind, Maggie, Lipshultz, Steven E, Liu, Shiwei, Liu, Yang, Lloyd, Belinda K, Lofgren, Katherine T, Logroscino, Giancarlo, Looker, Katharine J, Lortet-Tieulent, Joannie, Lotufo, Paulo A, Lozano, Rafael, Lucas, Robyn M, Lunevicius, Raimundas, Lyons, Ronan A, Ma, Stefan, Macintyre, Michael F, Mackay, Mark T, Majdan, Marek, Malekzadeh, Reza, Marcenes, Wagner, Margolis, David J, Margono, Christopher, Marzan, Melvin B, Masci, Joseph R, Mashal, Mohammad T, Matzopoulos, Richard, Mayosi, Bongani M, Mazorodze, Tasara T, Mcgill, Neil W, Mcgrath, John J, Mckee, Martin, Mclain, Abigail, Meaney, Peter A, Medina, Catalina, Mehndiratta, Man Mohan, Mekonnen, Wubegzier, Melaku, Yohannes A, Meltzer, Michele, Memish, Ziad A, Mensah, George A, Meretoja, Atte, Mhimbira, Francis A, Micha, Renata, Miller, Ted R, Mills, Edward J, Mitchell, Philip B, Mock, Charles N, Ibrahim, Norlinah Mohamed, Mohammad, Karzan A, Mokdad, Ali H, Mola, Glen L D, Monasta, Lorenzo, Hernandez, Julio C Montañez, Montico, Marcella, Montine, Thomas J, Mooney, Meghan D, Moore, Ami R, Moradi-Lakeh, Maziar, Moran, Andrew E, Mori, Rintaro, Moschandreas, Joanna, Moturi, Wilkister N, Moyer, Madeline L, Mozaffarian, Dariush, Msemburi, William T, Mueller, Ulrich O, Mukaigawara, Mitsuru, Mullany, Erin C, Murdoch, Michele E, Murray, Joseph, Murthy, Kinnari S, Naghavi, Mohsen, Naheed, Aliya, Naidoo, Kovin S, Naldi, Luigi, Nand, Devina, Nangia, Vinay, Narayan, K M Venkat, Nejjari, Chakib, Neupane, Sudan P, Newton, Charles R, Ng, Marie, Ngalesoni, Frida N, Nguyen, Grant, Nisar, Muhammad I, Nolte, Sandra, Norheim, Ole F, Norman, Rosana E, Norrving, Bo, Nyakarahuka, Luke, Oh, In-Hwan, Ohkubo, Takayoshi, Ohno, Summer L, Olusanya, Bolajoko O, Opio, John Nelson, Ortblad, Katrina, Ortiz, Alberto, Pain, Amanda W, Pandian, Jeyaraj D, Panelo, Carlo Irwin A, Papachristou, Christina, Park, Eun-Kee, Park, Jae-Hyun, Patten, Scott B, Patton, George C, Paul, Vinod K, Pavlin, Boris I, Pearce, Neil, Pereira, David M, Perez-Padilla, Rogelio, Perez-Ruiz, Fernando, Perico, Norberto, Pervaiz, Aslam, Pesudovs, Konrad, Peterson, Carrie B, Petzold, Max, Phillips, Michael R, Phillips, Bryan K, Phillips, David E, Piel, Frédéric B, Plass, Dietrich, Poenaru, Dan, Polinder, Suzanne, Pope, Daniel, Popova, Svetlana, Poulton, Richie G, Pourmalek, Farshad, Prabhakaran, Dorairaj, Prasad, Noela M, Pullan, Rachel L, Qato, Dima M, Quistberg, D Alex, Rafay, Anwar, Rahimi, Kazem, Rahman, Sajjad U, Raju, Murugesan, Rana, Saleem M, Razavi, Homie, Reddy, K Srinath, Refaat, Amany, Remuzzi, Giuseppe, Resnikoff, Serge, Ribeiro, Antonio L, Richardson, Lee, Richardus, Jan Hendrik, Roberts, D Allen, Rojas-Rueda, David, Ronfani, Luca, Roth, Gregory A, Rothenbacher, Dietrich, Rothstein, David H, Rowley, Jane T, Roy, Nobhojit, Ruhago, George M, Saeedi, Mohammad Y, Saha, Sukanta, Sahraian, Mohammad Ali, Sampson, Uchechukwu K A, Sanabria, Juan R, Sandar, Logan, Santos, Itamar S, Satpathy, Maheswar, Sawhney, Monika, Scarborough, Peter, Schneider, Ione J, Schöttker, Ben, Schumacher, Austin E, Schwebel, David C, Scott, James G, Seedat, Soraya, Sepanlou, Sadaf G, Serina, Peter T, Servan-Mori, Edson E, Shackelford, Katya A, Shaheen, Amira, Shahraz, Saeid, Levy, Teresa Shamah, Shangguan, Siyi, She, Jun, Sheikhbahaei, Sara, Shi, Peilin, Shibuya, Kenji, Shinohara, Yukito, Shiri, Rahman, Shishani, Kawkab, Shiue, Ivy, Shrime, Mark G, Sigfusdottir, Inga D, Silberberg, Donald H, Simard, Edgar P, Sindi, Shireen, Singh, Abhishek, Singh, Jasvinder A, Singh, Lavanya, Skirbekk, Vegard, Slepak, Erica Leigh, Sliwa, Karen, Soneji, Samir, Søreide, Kjetil, Soshnikov, Sergey, Sposato, Luciano A, Sreeramareddy, Chandrashekhar T, Stanaway, Jeffrey D, Stathopoulou, Vasiliki, Stein, Dan J, Stein, Murray B, Steiner, Caitlyn, Steiner, Timothy J, Stevens, Antony, Stewart, Andrea, Stovner, Lars J, Stroumpoulis, Konstantinos, Sunguya, Bruno F, Swaminathan, Soumya, Swaroop, Mamta, Sykes, Bryan L, Tabb, Karen M, Takahashi, Ken, Tandon, Nikhil, Tanne, David, Tanner, Marcel, Tavakkoli, Mohammad, Taylor, Hugh R, Ao, Braden J Te, Tediosi, Fabrizio, Temesgen, Awoke M, Templin, Tara, Ten Have, Margreet, Tenkorang, Eric Y, Terkawi, Abdullah S, Thomson, Blake, Thorne-Lyman, Andrew L, Thrift, Amanda G, Thurston, George D, Tillmann, Taavi, Tonelli, Marcello, Topouzis, Fotis, Toyoshima, Hideaki, Traebert, Jefferson, Tran, Bach X, Trillini, Matias, Truelsen, Thomas, Tsilimbaris, Miltiadis, Tuzcu, Emin M, Uchendu, Uche S, Ukwaja, Kingsley N, Undurraga, Eduardo A, Uzun, Selen B, Van Brakel, Wim H, Van De Vijver, Steven, van Gool, Coen H, Van Os, Jim, Vasankari, Tommi J, Venketasubramanian, N, Violante, Francesco S, Vlassov, Vasiliy V, Vollset, Stein Emil, Wagner, Gregory R, Wagner, Joseph, Waller, Stephen G, Wan, Xia, Wang, Haidong, Wang, Jianli, Wang, Linhong, Warouw, Tati S, Weichenthal, Scott, Weiderpass, Elisabete, Weintraub, Robert G, Wenzhi, Wang, Werdecker, Andrea, Westerman, Ronny, Whiteford, Harvey A, Wilkinson, James D, Williams, Thomas N, Wolfe, Charles D, Wolock, Timothy M, Woolf, Anthony D, Wulf, Sarah, Wurtz, Brittany, Xu, Gelin, Yan, Lijing L, Yano, Yuichiro, Ye, Pengpeng, Yentür, Gökalp K, Yip, Paul, Yonemoto, Naohiro, Yoon, Seok-Jun, Younis, Mustafa Z, Yu, Chuanhua, Zaki, Maysaa E, Zhao, Yong, Zheng, Yingfeng, Zonies, David, Zou, Xiaonong, Salomon, Joshua A, Lopez, Alan D, and Vos, Theo

Published
2015
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9. Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013

Author

Vos, Theo, Barber, Ryan M, Bell, Brad, Bertozzi-Villa, Amelia, Biryukov, Stan, Bolliger, Ian, Charlson, Fiona, Davis, Adrian, Degenhardt, Louisa, Dicker, Daniel, Duan, Leilei, Erskine, Holly, Feigin, Valery L, Ferrari, Alize J, Fitzmaurice, Christina, Fleming, Thomas, Graetz, Nicholas, Guinovart, Caterina, Haagsma, Juanita, Hansen, Gillian M, Hanson, Sarah Wulf, Heuton, Kyle R, Higashi, Hideki, Kassebaum, Nicholas, Kyu, Hmwe, Laurie, Evan, Liang, Xiofeng, Lofgren, Katherine, Lozano, Rafael, MacIntyre, Michael F, Moradi-Lakeh, Maziar, Naghavi, Mohsen, Nguyen, Grant, Odell, Shaun, Ortblad, Katrina, Roberts, David Allen, Roth, Gregory A, Sandar, Logan, Serina, Peter T, Stanaway, Jeffrey D, Steiner, Caitlyn, Thomas, Bernadette, Vollset, Stein Emil, Whiteford, Harvey, Wolock, Timothy M, Ye, Pengpeng, Zhou, Maigeng, Ãvila, Marco A, Aasvang, Gunn Marit, Abbafati, Cristiana, Ozgoren, Ayse Abbasoglu, Abd-Allah, Foad, Aziz, Muna I Abdel, Abera, Semaw F, Aboyans, Victor, Abraham, Jerry P, Abraham, Biju, Abubakar, Ibrahim, Abu-Raddad, Laith J, Abu-Rmeileh, Niveen ME, Aburto, Tania C, Achoki, Tom, Ackerman, Ilana N, Adelekan, Ademola, Ademi, Zanfina, Adou, Arsène K, Adsuar, Josef C, Arnlov, Johan, Agardh, Emilie E, Al Khabouri, Mazin J, Alam, Sayed Saidul, Alasfoor, Deena, Albittar, Mohammed I, Alegretti, Miguel A, Aleman, Alicia V, Alemu, Zewdie A, Alfonso-Cristancho, Rafael, Alhabib, Samia, Ali, Raghib, Alla, Francois, Allebeck, Peter, Allen, Peter J, AlMazroa, Mohammad AbdulAziz, Alsharif, Ubai, Alvarez, Elena, Alvis-Guzman, Nelson, Ameli, Omid, Amini, Heresh, Ammar, Walid, Anderson, Benjamin O, Anderson, H. Ross, Antonio, Carl Abelardo T, Anwari, Palwasha, Apfel, Henry, Arsenijevic, Valentain S Arsic, Artaman, Al, Asghar, Rana J, Assadi, Reza, Atkins, Lydia S, Atkinson, Charles, Badawi, Alaa, Bahit, Maria C, Bakfalouni, Talal, Balakrishnan, Kalpana, Balalla, Shivanthi, Banerjee, Amitava, Barker-Collo, Suzanne L, Barquera, Simon, Barregard, Lars, Barrero, Lope H, Basu, Sanjay, Basu, Arindam, Baxter, Amanda, Beardsley, Justin, Bedi, Neeraj, Beghi, Ettore, Bekele, Tolesa, Bell, Michelle L, Benjet, Corina, Bennett, Derrick A, Bensenor, Isabela M, Benzian, Habib, Bernabe, Eduardo, Beyene, Tariku J, Bhala, Neeraj, Bhalla, Ashish, Bhutta, Zulfiqar, Bienhoff, Kelly, Bikbov, Boris, Abdulhak, Aref Bin, Blore, Jed D, Blyth, Fiona M, Bohensky, Megan A, Basara, Berrak Bora, Borges, Guilherme, Bornstein, Natan M, Bose, Dipan, Boufous, Soufiane, Bourne, Rupert R, Boyers, Lindsay N, Brainin, Michael, Brauer, Michael, Brayne, Carol EG, Brazinova, Alexandra, Breitborde, Nicholas JK, Brenner, Hermann, Briggs, Adam DM, Brooks, Peter M, Brown, Jonathan, Brugha, Traolach S, Buchbinder, Rachelle, Buckle, Geoffrey C, Bukhman, Gene, Bulloch, Andrew G, Burch, Michael, Burnett, Richard, Cardenas, Rosario, Cabral, Norberto L, Nonato, Ismael R Campos, Campuzano, Julio C, Carapetis, Jonathan R, Carpenter, David O, Caso, Valeria, Castaneda-Orjuela, Carlos A, Catala-Lopez, Ferran, Chadha, Vineet K, Chang, Jung-Chen, Chen, Honglei, Chen, Wanqing, Chiang, Peggy P, Chimed-Ochir, Odgerel, Chowdhury, Rajiv, Christensen, Hanne, Christophi, Costas A, Chugh, Sumeet S, Cirillo, Massimo, Coggeshall, Megan, Cohen, Aaron, Colistro, Valentina, Colquhoun, Samantha M, Contreras, Alejandra G, Cooper, Leslie T, Cooper, Cyrus, Cooperrider, Kimberly, Coresh, Josef, Cortinovis, Monica, Criqui, Michael H, Crump, John A, Cuevas-Nasu, Lucia, Dandona, Rakhi, Dandona, Lalit, Dansereau, Emily, Dantes, Hector G, Dargan, Paul I, Davey, Gail, Davitoiu, Dragos V, Dayama, Anand, De la Cruz-Gongora, Vanessa, de la Vega, Shelley F, De Leo, Diego, del Pozo-Cruz, Borja, Dellavalle, Robert P, Deribe, Kebede, Derrett, Sarah, Des Jarlais, Don C, Dessalegn, Muluken, deVeber, Gabrielle A, Dharmaratne, Samath D, Diaz-Torne, Cesar, Ding, Eric L, Dokova, Klara, Dorsey, E R, Driscoll, Tim R, Duber, Herbert, Durrani, Adnan M, Edmond, Karen M, Ellenbogen, Richard G, Endres, Matthias, Ermakov, Sergey P, Eshrati, Babak, Esteghamati, Alireza, Estep, Kara, Fahimi, Saman, Farzadfar, Farshad, Fay, Derek FJ, Felson, David T, Fereshtehnejad, Seyed-Mohammad, Fernandes, Jefferson G, Ferri, Cluesa P, Flaxman, Abraham, Foigt, Nataliya, Foreman, Kyle J, Fowkes, F Gerry R, Franklin, Richard C, Furst, Thomas, Futran, Neal D, Gabbe, Belinda J, Gankpe, Fortune G, Garcia-Guerra, Francisco A, Geleijnse, Johanna M, Gessner, Bradford D, Gibney, Katherine B, Gillum, Richard F, Ginawi, Ibrahim A, Giroud, Maurice, Giussani, Giorgia, Goenka, Shifalika, Goginashvili, Ketevan, Gona, Philimon, de Cosio, Teresita Gonzalez, Gosselin, Richard A, Gotay, Carolyn C, Goto, Atsushi, Gouda, Hebe N, Guerrant, Richard l, Gugnani, Harish C, Gunnell, David, Gupta, Rajeev, Gupta, Rahul, Gutierrez, Reyna A, Hafezi-Nejad, Nima, Hagan, Holly, Halasa, Yara, Hamadeh, Randah R, Hamavid, Hannah, Hammami, Mouhanad, Hankey, Graeme J, Hao, Yuantao, Harb, Hilda L, Haro, Josep Maria, Havmoeller, Rasmus, Hay, Roderick J, Hay, Simon, Hedayati, Mohammad T, Pi, Ileana B Heredia, Heydarpour, Pouria, Hijar, Martha, Hoek, Hans W, Hoffman, Howard J, Hornberger, John C, Hosgood, H. Dean, Hossain, Mazeda, Hotez, Peter J, Hoy, Damian G, Hsairi, Mohamed, Hu, Howard, Hu, Guoqing, Huang, John J, Huang, Cheng, Huiart, Laetitia, Husseini, Abdullatif, Iannarone, Marissa, Iburg, Kim M, Innos, Kaire, Inoue, Manami, Jacobsen, Kathryn H, Jassal, Simerjot K, Jeemon, Panniyammakal, Jensen, Paul N, Jha, Vivekanand, Jiang, Guohong, Jiang, Ying, Jonas, Jost B, Joseph, Jonathan, Juel, Knud, Kan, Haidong, Karch, Andre, Karimkhani, Chante, Karthikeyan, Ganesan, Katz, Ronit, Kaul, Anil, Kawakami, Norito, Kazi, Dhruv S, Kemp, Andrew H, Kengne, Andre P, Khader, Yousef S, Khalifa, Shams Eldin AH, Khan, Ejaz A, Khan, Gulfaraz, Khang, Young-Ho, Khonelidze, Irma, Kieling, Christian, Kim, Daniel, Kim, Sungroul, Kimokoti, Ruth W, Kinfu, Yohannes, Kinge, Jonas M, Kissela, Brett M, Kivipelto, Miia, Knibbs, Luke, Knudsen, Ann Kristin, Kokubo, Yoshihiro, Kosen, Soewarta, Kramer, Alexander, Kravchenko, Michael, Krishnamurthi, Rita V, Krishnaswami, Sanjay, Defo, Barthelemy Kuate, Bicer, Burcu Kucuk, Kuipers, Ernst J, Kulkarni, Veena S, Kumar, Kaushalendra, Kumar, G Anil, Kwan, Gene F, Lai, Taavi, Lalloo, Ratilal, Lam, Hilton, Lan, Qing, Lansingh, Van C, Larson, Heidi, Larsson, Anders, Lawrynowicz, Alicia EB, Leasher, Janet L, Lee, Jong-Tae, Leigh, James, Leung, Ricky, Levi, Miriam, Li, Bin, Li, Yichong, Li, Yongmei, liang, Juan, Lim, Stephen, Lin, Hsien-Ho, Lind, Margaret, Lindsay, M Patrice, Lipshultz, Steven E, Liu, Shiwei, Lloyd, Belinda K, Ohno, Summer Lockett, Logroscino, Giancarlo, Looker, Katharine J, Lopez, Alan D, Lopez-Olmedo, Nancy, Lortet-Tieulent, Joannie, Lotufo, Paulo A, Low, Nicola, Lucas, Robyn M, Lunevicius, Raimundas, Lyons, Ronan A, Ma, Jixiang, Ma, Stefan, Mackay, Mark T, Majdan, Marek, Malekzadeh, Reza, Mapoma, Christopher C, Marcenes, Wagner, March, Lyn M, Margono, Chris, Marks, Guy B, Marzan, Melvin B, Masci, Joseph R, Mason-Jones, Amanda J, Matzopoulos, Richard G, Mayosi, Bongani M, Mazorodze, Tasara T, McGill, Neil W, McGrath, John J, McKee, Martin, McLain, Abby, McMahon, Brian J, Meaney, Peter A, Mehndiratta, Man Mohan, Mejia-Rodriguez, Fabiola, Mekonnen, Wubegzier, Melaku, Yohannes A, Meltzer, Michele, Memish, Ziad A, Mensah, George, Meretoja, Atte, Mhimbira, Francis A, Micha, Renata, Miller, Ted R, Mills, Edward J, Mitchell, Philip B, Mock, Charles N, Moffitt, Terrie E, Ibrahim, Norlinah Mohamed, Mohammad, Karzan A, Mokdad, Ali H, Mola, Glen L, Monasta, Lorenzo, Montico, Marcella, Montine, Thomas J, Moore, Ami R, Moran, Andrew E, Morawska, Lidia, Mori, Rintaro, Moschandreas, Joanna, Moturi, Wilkister N, Moyer, Madeline, Mozaffarian, Dariush, Mueller, Ulrich O, Mukaigawara, Mitsuru, Murdoch, Michele E, Murray, Joseph, Murthy, Kinnari S, Naghavi, Paria, Nahas, Ziad, Naheed, Aliya, Naidoo, Kovin S, Naldi, Luigi, Nand, Devina, Nangia, Vinay, Narayan, K.M. Venkat, Nash, Denis, Nejjari, Chakib, Neupane, Sudan P, Newman, Lori M, Newton, Charles R, Ng, Marie, Ngalesoni, Frida N, Nhung, Nguyen T, Nisar, Muhammad I, Nolte, Sandra, Norheim, Ole F, Norman, Rosana E, Norrving, Bo, Nyakarahuka, Luke, Oh, In Hwan, Ohkubo, Takayoshi, Omer, Saad B, Opio, John Nelson, Ortiz, Alberto, Pandian, Jeyaraj D, Panelo, Carlo Irwin A, Papachristou, Christina, Park, Eun-Kee, Parry, Charles D, Caicedo, Angel J Paternina, Patten, Scott B, Paul, Vinod K, Pavlin, Boris I, Pearce, Neil, Pedraza, Lilia S, Pellegrini, Carlos A, Pereira, David M, Perez-Ruiz, Fernando P, Perico, Norberto, Pervaiz, Aslam, Pesudovs, Konrad, Peterson, Carrie B, Petzold, Max, Phillips, Michael R, Phillips, David, Phillips, Bryan, Piel, Frederic B, Plass, Dietrich, Poenaru, Dan, Polanczyk, Guilherme V, Polinder, Suzanne, Pope, C A, Popova, Svetlana, Poulton, Richie G, Pourmalek, Farshad, Prabhakaran, Dorairaj, Prasad, Noela M, Qato, Dima, Quistberg, D A, Rafay, Anwar, Rahimi, Kazem, Rahimi-Movaghar, Vafa, Rahman, Sajjad ur, Raju, Murugesan, Rakovac, Ivo, Rana, Saleem M, Razavi, Homie, Refaat, Amany, Rehm, Jurgen, Remuzzi, Giuseppe, Resnikoff, Serge, Ribeiro, Antonio L, Riccio, Patricia M, Richardson, Lee, Richardus, Jan Hendrik, Riederer, Anne M, Robinson, Margot, Roca, Anna, Rodriguez, Alina, Rojas-Rueda, David, Ronfani, Luca, Rothenbacher, Dietrich, Roy, Nobhojit, Ruhago, George M, Sabin, Nsanzimana, Sacco, Ralph L, Ksoreide, Kjetil, Saha, Sukanta, Sahathevan, Ramesh, Sahraian, Mohammad Ali, Sampson, Uchechukwu, Sanabria, Juan R, Sanchez-Riera, Lidia, Santos, Itamar S, Satpathy, Maheswar, Saunders, James E, Sawhney, Monika, Saylan, Mete I, Scarborough, Peter, Schoettker, Ben, Schneider, Ione JC, Schwebel, David C, Scott, James G, Seedat, Soraya, Sepanlou, Sadaf G, Serdar, Berrin, Servan-Mori, Edson E, Shackelford, Katya, Shaheen, Amira, Shahraz, Saeid, Levy, Teresa Shamah, Shangguan, Siyi, She, Jun, Sheikhbahaei, Sara, Shepard, Donald S, Shi, Peilin, Shibuya, Kenji, Shinohara, Yukito, Shiri, Rahman, Shishani, Kawkab, Shiue, Ivy, Shrime, Mark G, Sigfusdottir, Inga D, Silberberg, Donald H, Simard, Edgar P, Sindi, Shireen, Singh, Jasvinder A, Singh, Lavanya, Skirbekk, Vegard, Sliwa, Karen, Soljak, Michael, Soneji, Samir, Soshnikov, Sergey S, Speyer, Peter, Sposato, Luciano A, Sreeramareddy, Chandrashekhar T, Stoeckl, Heidi, Stathopoulou, Vasiliki Kalliopi, Steckling, Nadine, Stein, Murray B, Stein, Dan J, Steiner, Timothy J, Stewart, Andrea, Stork, Eden, Stovner, Lars J, Stroumpoulis, Konstantinos, Sturua, Lela, Sunguya, Bruno F, Swaroop, Mamta, Sykes, Bryan L, Tabb, Karen M, Takahashi, Ken, Tan, Feng, Tandon, Nikhil, Tanne, David, Tanner, Marcel, Tavakkoli, Mohammad, Taylor, Hugh R, Te Ao, Braden J, Temesgen, Awoke Misganaw, Have, Margreet Ten, Tenkorang, Eric Yeboah, Terkawi, Abdullah Sulieman, Theadom, Alice M, Thomas, Elissa, Thorne-Lyman, Andrew L, Thrift, Amanda G, Tleyjeh, Imad M, Tonelli, Marcello, Topouzis, Fotis, Towbin, Jeffrey A, Toyoshima, Hideaki, Traebert, Jefferson, Tran, Bach X, Trasande, Leonardo, Trillini, Matias, Truelsen, Thomas, Trujillo, Ulises, Tsilimbaris, Miltiadis, Tuzcu, Emin M, Ukwaja, Kingsley N, Undurraga, Eduardo A, Uzun, Selen B, van Brakel, Wim H, van de Vijver, Steven, Dingenen, Rita Van, van Gool, Coen H, Varakin, Yuri Y, Vasankari, Tommi J, Vavilala, Monica S, Veerman, Lennert J, Velasquez-Melendez, Gustavo, Venketasubramanian, Narayanaswamy, Vijayakumar, Lakshmi, Villalpando, Salvador, Violante, Francesco S, Vlassov, Vasiliy V, Waller, Stephen, Wallin, Mitchell T, Wan, Xia, Wang, Linhong, Wang, JianLi, Wang, Yanping, Warouw, Tati S, Weichenthal, Scott, Weiderpass, Elisabete, Weintraub, Robert G, Werdecker, Andrea, Wessells, K. Ryan R, Westerman, Ronny, Wilkinson, James D, Williams, Hywel C, Williams, Thomas N, Woldeyohannes, Solomon M, Wolfe, Charles DA, Wong, John Q, Wong, Haidong, Woolf, Anthony D, Wright, Jonathan L, Wurtz, Brittany, Xu, Gelin, Yang, Gonghuan, Yano, Yuichiro, Yenesew, Muluken A, Yentur, Gokalp K, Yip, Paul, Yonemoto, Naohiro, Yoon, Seok-Jun, Younis, Mustafa, Yu, Chuanhua, Kim, Kim Yun, Zaki, Maysaa El Sayed, Zhang, Yong, Zhao, Zheng, Zhao, Yong, Zhu, Jun, Zonies, David, Zunt, Joseph R, Salomon, Joshua A, and Murray, Christopher JL

Published
2015
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10. sj-docx-1-jpx-10.1177_23743735231160418 - Supplemental material for Physician Views of Telehealth for Special Populations of Older Adults: Preliminary Findings

Author

Serina, Peter T, Davoodi, Natalie M, Guthrie, Kate M, Merchant, Roland C, and Goldberg, Elizabeth M

Subjects
111708 Health and Community Services, Medicine, FOS: Health sciences
Abstract

Supplemental material, sj-docx-1-jpx-10.1177_23743735231160418 for Physician Views of Telehealth for Special Populations of Older Adults: Preliminary Findings by Peter T Serina, Natalie M Davoodi, Kate M Guthrie, Roland C Merchant and Elizabeth M Goldberg in Journal of Patient Experience

Published
2023
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16. Effect of Standardized Handoff Curriculum on Improved Clinician Preparedness in the Intensive Care Unit

Author

Parent, Brodie, primary, LaGrone, Lacey N., additional, Albirair, Mohamed T., additional, Serina, Peter T., additional, Keller, Jonathan M., additional, Cuschieri, Joseph, additional, Addison, Erin J., additional, Choe, Lapio, additional, Delossantos, Genecelle B., additional, Gaskill, Cameron E., additional, Moon, Sarah D., additional, MacDonald, Jestine T., additional, Stolzberg, Matthew J., additional, Van Eaton, Erik G., additional, Zech, Jennifer M., additional, and Kritek, Patricia A., additional

Published
2018
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17. Global and national Burden of diseases and injuries among children and adolescents between 1990 and 2013

Author

Kyu, Hmwe H., Pinho, Christine, Wagner, Joseph A., Brown, Jonathan C., Bertozzi-Villa, Amelia, Charlson, Fiona J., Coffeng, Luc Edgar, Dandona, Lalit, Erskine, Holly E., Ferrari, Alize J., Fitzmaurice, Christina, Fleming, Thomas D., Forouzanfar, Mohammad H., Graetz, Nicholas, Guinovart, Caterina, Haagsma, Juanita, Higashi, Hideki, Kassebaum, Nicholas J., Larson, Heidi J., Lim, Stephen S., Mokdad, Ali H., Moradi-Lakeh, Maziar, Odell, Shaun V., Roth, Gregory A., Serina, Peter T., Stanaway, Jeffrey D., Misganaw, Awoke, Whiteford, Harvey A., Wolock, Timothy M., Wulf Hanson, Sarah, Abd-Allah, Foad, Abera, Semaw Ferede, Abu-Raddad, Laith J., AlBuhairan, Fadia S., Amare, Azmeraw T., Antonio, Carl Abelardo T., Artaman, Al, Barker-Collo, Suzanne L., Barrero, Lope H., Benjet, Corina, Bensenor, Isabela M., Bhutta, Zulfiqar A., Bikbov, Boris, Brazinova, Alexandra, Campos-Nonato, Ismael, Castañeda-Orjuela, Carlos A., Catalá-López, Ferrán, Chowdhury, Rajiv, Cooper, Cyrus, Crump, John A., Dandona, Rakhi, Degenhardt, Louisa, Dellavalle, Robert P., Dharmaratne, Samath D., Faraon, Emerito Jose A., Feigin, Valery L., Fürst, Thomas, Geleijnse, Johanna M., Gessner, Bradford D., Gibney, Katherine B., Goto, Atsushi, Gunnell, David, Hankey, Graeme J., Hay, Roderick J., Hornberger, John C., Hosgood, H. Dean, Hu, Guoqing, Jacobsen, Kathryn H., Jayaraman, Sudha P., Jeemon, Panniyammakal, Jonas, Jost B., Karch, André, Kim, Daniel, Kim, Sungroul, Kokubo, Yoshihiro, Kuate Defo, Barthelemy, Kucuk Bicer, Burcu, Kumar, G. Anil, Larsson, Anders, Leasher, Janet L., Leung, Ricky, Li, Yongmei, Lipshultz, Steven E., Lopez, Alan D., Lotufo, Paulo A., Lunevicius, Raimundas, Lyons, Ronan A., Majdan, Marek, Malekzadeh, Reza, Mashal, Taufiq, Mason-Jones, Amanda J., Melaku, Yohannes Adama, Memish, Ziad A., Mendoza, Walter, Miller, Ted R., Mock, Charles N., Murray, Joseph, Nolte, Sandra, Oh, In-Hwan, Olusanya, Bolajoko Olubukunola, Ortblad, Katrina F., Park, Eun-Kee, Paternina Caicedo, Angel J., Patten, Scott B., Patton, George C., Pereira, David M., Perico, Norberto, Piel, Frédéric B., Polinder, Suzanne, Popova, Svetlana, Pourmalek, Farshad, Quistberg, D. Alex, Remuzzi, Giuseppe, Rodriguez, Alina, Rojas-Rueda, David, Rothenbacher, Dietrich, Rothstein, David H., Sanabria, Juan, Santos, Itamar S., Schwebel, David C., Sepanlou, Sadaf G., Shaheen, Amira, Shiri, Rahman, Shiue, Ivy, Skirbekk, Vegard, Sliwa, Karen, Sreeramareddy, Chandrashekhar T., Stein, Dan J., Steiner, Timothy J., Stovner, Lars Jacob, Sykes, Bryan L., Tabb, Karen M., Terkawi, Abdullah Sulieman, Thomson, Alan J., Thorne-Lyman, Andrew L., Towbin, Jeffrey Allen, Ukwaja, Kingsley Nnanna, Vasankari, Tommi, Venketasubramanian, Narayanaswamy, Vlassov, Vasiliy Victorovich, Vollset, Stein Emil, Weiderpass, Elisabete, Weintraub, Robert G., Werdecker, Andrea, Wilkinson, James D., Woldeyohannes, Solomon Meseret, Wolfe, Charles D. A., Yano, Yuichiro, Yip, Paul, Yonemoto, Naohiro, Yoon, Seok-Jun, Younis, Mustafa Z., Yu, Chuanhua, El Sayed Zaki, Maysaa, Naghavi, Mohsen, Murray, Christopher J. L., and Vos, Theo

Subjects
L510 Health & Welfare
Abstract

Importance The literature focuses on mortality among children younger than 5 years. Comparable information on nonfatal health outcomes among these children and the fatal and nonfatal burden of diseases and injuries among older children and adolescents is scarce. Objective To determine levels and trends in the fatal and nonfatal burden of diseases and injuries among younger children (aged

Published
2016

18. Collecting verbal autopsies: improving and streamlining data collection processes using electronic tablets

Author

Flaxman, Abraham D., primary, Stewart, Andrea, additional, Joseph, Jonathan C., additional, Alam, Nurul, additional, Alam, Sayed Saidul, additional, Chowdhury, Hafizur, additional, Mooney, Meghan D., additional, Rampatige, Rasika, additional, Remolador, Hazel, additional, Sanvictores, Diozele, additional, Serina, Peter T., additional, Streatfield, Peter Kim, additional, Tallo, Veronica, additional, Murray, Christopher J. L., additional, Hernandez, Bernardo, additional, Lopez, Alan D., additional, and Riley, Ian Douglas, additional

Published
2018
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19. Global And National Burden Of Diseases And Injuries Among Children And Adolescents Between 1990 And 2013 Findings From The Global Burden Of Disease 2013 Study

Author

Kyu, Hmwe H., Pinho, Christine, Wagner, Joseph A., Brown, Jonathan C., Bertozzi-Villa, Amelia, Charlson, Fiona J., Coffeng, Luc Edgar, Dandona, Lalit, Erskine, Holly E., Ferrari, Alize J., Fitzmaurice, Christina, Fleming, Thomas D., Forouzanfar, Mohammad H., Graetz, Nicholas, Guinovart, Caterina, Haagsma, Juanita, Higashi, Hideki, Kassebaum, Nicholas J., Larson, Heidi J., Lim, Stephen S., Mokdad, Ali H., Moradi-Lakeh, Maziar, Odell, Shaun V., Roth, Gregory A., Serina, Peter T., Stanaway, Jeffrey D., Misganaw, Awoke, Whiteford, Harvey A., Wolock, Timothy M., Hanson, Sarah Wulf, Abd-Allah, Foad, Abera, Semaw Ferede, Abu-Raddad, Laith J., AlBuhairan, Fadia S., Amare, Azmeraw T., Antonio, Carl Abelardo T., Artaman, Al, Barker-Collo, Suzanne L., Barrero, Lope H., Benjet, Corina, Bensenor, Isabela M., Bhutta, Zulfiqar A., Bikbov, Boris, Brazinova, Alexandra, Campos-Nonato, Ismael, Castaneda-Orjuela, Carlos A., Catala-Lopez, Ferran, Chowdhury, Rajiv, Cooper, Cyrus, Crump, John A., Dandona, Rakhi, Degenhardt, Louisa, Dellavalle, Robert P., Dharmaratne, Samath D., Faraon, Emerito Jose A., Feigin, Valery L., Fuerst, Thomas, Geleijnse, Johanna M., Gessner, Bradford D., Gibney, Katherine B., Goto, Atsushi, Gunnell, David, Hankey, Graeme J., Hay, Roderick J., Hornberger, John C., Hosgood, H. Dean, Hu, Guoqing, Jacobsen, Kathryn H., Jayaraman, Sudha P., Jeemon, Panniyammakal, Jonas, Jost B., Karch, Andre, Kim, Daniel, Kim, Sungroul, Kokubo, Yoshihiro, Defo, Barthelemy Kuate, Bicer, Burcu Kucuk, Kumar, G. Anil, Larsson, Anders, Leasher, Janet L., Leung, Ricky, Li, Yongmei, Lipshultz, Steven E., Lopez, Alan D., Lotufo, Paulo A., Lunevicius, Raimundas, Lyons, Ronan A., Majdan, Marek, Malekzadeh, Reza, Mashal, Taufiq, Mason-Jones, Amanda J., Melaku, Yohannes Adama, Memish, Ziad A., Mendoza, Walter, Miller, Ted R., Mock, Charles N., Murray, Joseph, Nolte, Sandra, Oh, In-Hwan, Olusanya, Bolajoko Olubukunola, Ortblad, Katrina F., Park, Eun-Kee, Paternina Caicedo, Angel J., Patten, Scott B., Patton, George C., Pereira, David M., Perico, Norberto, Piel, Frederic B., Polinder, Suzanne, Popova, Svetlana, Pourmalek, Farshad, Quistberg, D. Alex, Remuzzi, Giuseppe, Rodriguez, Alina, Rojas-Rueda, David, Rothenbacher, Dietrich, Rothstein, David H., Sanabria, Juan, Santos, Itamar S., Schwebel, David C., Sepanlou, Sadaf G., Shaheen, Amira, Shiri, Rahman, Shiue, Ivy, Skirbekk, Vegard, Sliwa, Karen, Sreeramareddy, Chandrashekhar T., Stein, Dan J., Steiner, Timothy J., Stovner, Lars Jacob, Sykes, Bryan L., Tabb, Karen M., Terkawi, Abdullah Sulieman, Thomson, Alan J., Thorne-Lyman, Andrew L., Towbin, Jeffrey Allen, Ukwaja, Kingsley Nnanna, Vasankari, Tommi, Venketasubramanian, Narayanaswamy, Vlassov, Vasiliy Victorovich, Vollset, Stein Emil, Weiderpass, Elisabete, Weintraub, Robert G., Werdecker, Andrea, Wilkinson, James D., Woldeyohannes, Solomon Meseret, Wolfe, Charles D. A., Yano, Yuichiro, Yip, Paul, Yonemoto, Naohiro, Yoon, Seok-Jun, Younis, Mustafa Z., Yu, Chuanhua, Zaki, Maysaa El Sayed, Naghavi, Mohsen, Murray, Christopher J. L., Vos, Theo, and Çocuk Sağlığı ve Hastalıkları

Subjects
Pediatrics
Abstract

IMPORTANCE The literature focuses on mortality among children younger than 5 years. Comparable information on nonfatal health outcomes among these children and the fatal and nonfatal burden of diseases and injuries among older children and adolescents is scarce. OBJECTIVE To determine levels and trends in the fatal and nonfatal burden of diseases and injuries among younger children (aged < 5 years), older children (aged 5-9 years), and adolescents (aged 10-19 years) between 1990 and 2013 in 188 countries from the Global Burden of Disease (GBD) 2013 study. EVIDENCE REVIEW Data from vital registration, verbal autopsy studies, maternal and child death surveillance, and other sources covering 14 244 site-years (ie, years of cause of death data by geography) from 1980 through 2013 were used to estimate cause-specific mortality. Data from 35 620 epidemiological sources were used to estimate the prevalence of the diseases and sequelae in the GBD 2013 study. Cause-specific mortality for most causes was estimated using the Cause of Death Ensemble Model strategy. For some infectious diseases (eg, HIV infection/AIDS, measles, hepatitis B) where the disease process is complex or the cause of death data were insufficient or unavailable, we used natural history models. For most nonfatal health outcomes, DisMod-MR 2.0, a Bayesian metaregression tool, was used to meta-analyze the epidemiological data to generate prevalence estimates. FINDINGS Of the 7.7 (95% uncertainty interval [UI], 7.4-8.1) million deaths among children and adolescents globally in 2013, 6.28 million occurred among younger children, 0.48 million among older children, and 0.97 million among adolescents. In 2013, the leading causes of death were lower respiratory tract infections among younger children (905 059 deaths; 95% UI, 810304-998 125), diarrheal diseases among older children (38 325 deaths; 95% UI, 30 365-47 678), and road injuries among adolescents (115 186 deaths; 95% UI, 105 185-124 870). Iron deficiency anemia was the leading cause of years lived with disability among children and adolescents, affecting 619 (95% UI, 618-621) million in 2013. Large between-country variations exist in mortality from leading causes among children and adolescents. Countries with rapid declines in all-cause mortality between 1990 and 2013 also experienced large declines in most leading causes of death, whereas countries with the slowest declines had stagnant or increasing trends in the leading causes of death. In 2013, Nigeria had a 12% global share of deaths from lower respiratory tract infections and a 38% global share of deaths from malaria. India had 33% of the world's deaths from neonatal encephalopathy. Half of the world's diarrheal deaths among children and adolescents occurred in just 5 countries: India, Democratic Republic of the Congo, Pakistan, Nigeria, and Ethiopia. CONCLUSIONS AND RELEVANCE Understanding the levels and trends of the leading causes of death and disability among children and adolescents is critical to guide investment and inform policies. Monitoring these trends over time is also key to understanding where interventions are having an impact. Proven interventions exist to prevent or treat the leading causes of unnecessary death and disability among children and adolescents. The findings presented here show that these are underused and give guidance to policy makers in countries where more attention is needed.

Published
2016

20. Global and National Burden of Diseases and Injuries Among Children and Adolescents Between 1990 and 2013: Findings From the Global Burden of Disease 2013 Study

Author

Global Burden of Disease Pediatrics Collaboration, Kyu, Hmwe H, Pinho, Christine, Wagner, Joseph A, Brown, Jonathan C, Bertozzi-Villa, Amelia, Charlson, Fiona J, Coffeng, Luc Edgar, Dandona, Lalit, Erskine, Holly E, Ferrari, Alize J, Fitzmaurice, Christina, Fleming, Thomas D, Forouzanfar, Mohammad H, Graetz, Nicholas, Guinovart, Caterina, Haagsma, Juanita, Higashi, Hideki, Kassebaum, Nicholas J, Larson, Heidi J, Lim, Stephen S, Mokdad, Ali H, Moradi-Lakeh, Maziar, Odell, Shaun V, Roth, Gregory A, Serina, Peter T, Stanaway, Jeffrey D, Misganaw, Awoke, Whiteford, Harvey A, Wolock, Timothy M, Wulf Hanson, Sarah, Abd-Allah, Foad, Abera, Semaw Ferede, Abu-Raddad, Laith J, AlBuhairan, Fadia S, Amare, Azmeraw T, Antonio, Carl Abelardo T, Artaman, Al, Barker-Collo, Suzanne L, Barrero, Lope H, Benjet, Corina, Bensenor, Isabela M, Bhutta, Zulfiqar A, Bikbov, Boris, Brazinova, Alexandra, Campos-Nonato, Ismael, Castañeda-Orjuela, Carlos A, Catalá-López, Ferrán, Chowdhury, Rajiv, Cooper, Cyrus, Crump, John A, Dandona, Rakhi, Degenhardt, Louisa, Dellavalle, Robert P, Dharmaratne, Samath D, Faraon, Emerito Jose A, Feigin, Valery L, Fürst, Thomas, Geleijnse, Johanna M, Gessner, Bradford D, Gibney, Katherine B, Goto, Atsushi, Gunnell, David, Hankey, Graeme J, Hay, Roderick J, Hornberger, John C, Hosgood, H Dean, Hu, Guoqing, Jacobsen, Kathryn H, Jayaraman, Sudha P, Jeemon, Panniyammakal, Jonas, Jost B, Karch, André, Kim, Daniel, Kim, Sungroul, Kokubo, Yoshihiro, Kuate Defo, Barthelemy, Kucuk Bicer, Burcu, Kumar, G Anil, Larsson, Anders, Leasher, Janet L, Leung, Ricky, Li, Yongmei, Lipshultz, Steven E, Lopez, Alan D, Lotufo, Paulo A, Lunevicius, Raimundas, Lyons, Ronan A, Majdan, Marek, Malekzadeh, Reza, Mashal, Taufiq, Mason-Jones, Amanda J, Melaku, Yohannes Adama, Memish, Ziad A, Mendoza, Walter, Miller, Ted R, Mock, Charles N, Murray, Joseph, Nolte, Sandra, Oh, In-Hwan, Olusanya, Bolajoko Olubukunola, Ortblad, Katrina F, Park, Eun-Kee, Paternina Caicedo, Angel J, Patten, Scott B, Patton, George C, Pereira, David M, Perico, Norberto, Piel, Frédéric B, Polinder, Suzanne, Popova, Svetlana, Pourmalek, Farshad, Quistberg, D Alex, Remuzzi, Giuseppe, Rodriguez, Alina, Rojas-Rueda, David, Rothenbacher, Dietrich, Rothstein, David H, Sanabria, Juan, Santos, Itamar S, Schwebel, David C, Sepanlou, Sadaf G, Shaheen, Amira, Shiri, Rahman, Shiue, Ivy, Skirbekk, Vegard, Sliwa, Karen, Sreeramareddy, Chandrashekhar T, Stein, Dan J, Steiner, Timothy J, Stovner, Lars Jacob, Sykes, Bryan L, Tabb, Karen M, Terkawi, Abdullah Sulieman, Thomson, Alan J, Thorne-Lyman, Andrew L, Towbin, Jeffrey Allen, Ukwaja, Kingsley Nnanna, Vasankari, Tommi, Venketasubramanian, Narayanaswamy, Vlassov, Vasiliy Victorovich, Vollset, Stein Emil, Weiderpass, Elisabete, Weintraub, Robert G, Werdecker, Andrea, Wilkinson, James D, Woldeyohannes, Solomon Meseret, Wolfe, Charles DA, Yano, Yuichiro, Yip, Paul, Yonemoto, Naohiro, Yoon, Seok-Jun, Younis, Mustafa Z, Yu, Chuanhua, El Sayed Zaki, Maysaa, Naghavi, Mohsen, Murray, Christopher JL, and Vos, Theo

Abstract

IMPORTANCE: The literature focuses on mortality among children younger than 5 years. Comparable information on nonfatal health outcomes among these children and the fatal and nonfatal burden of diseases and injuries among older children and adolescents is scarce. OBJECTIVE: To determine levels and trends in the fatal and nonfatal burden of diseases and injuries among younger children (aged

Published
2016

21. Implementing the PHMRC shortened questionnaire: Survey duration of open and closed questions in three sites

Author

Flaxman, Abraham D., primary, Stewart, Andrea, additional, Joseph, Jonathan C., additional, Alam, Nurul, additional, Alam, Saidul, additional, Chowdhury, Hafizur, additional, Gamage, Saman, additional, Gouda, Hebe, additional, Joshi, Rohina, additional, Lucero, Marilla, additional, Mooney, Meghan D., additional, Praveen, Devarsetty, additional, Rampatige, Rasika, additional, Remolador, Hazel, additional, Sanvictores, Diozele, additional, Serina, Peter T., additional, Streatfield, Peter Kim, additional, Tallo, Veronica, additional, Wijesekera, Nandalal, additional, Murray, Christopher J. L., additional, Hernandez, Bernardo, additional, Lopez, Alan D., additional, and Riley, Ian Douglas, additional

Published
2017
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22. Global and National Burden of Diseases and Injuries Among Children and Adolescents Between 1990 and 2013 : Findings From the Global Burden of Disease 2013 Study

Author

Kyu, Hmwe H, Pinho, Christine, Wagner, Joseph A, Brown, Jonathan C, Bertozzi-Villa, Amelia, Charlson, Fiona J, Coffeng, Luc Edgar, Dandona, Lalit, Erskine, Holly E, Ferrari, Alize J, Fitzmaurice, Christina, Fleming, Thomas D, Forouzanfar, Mohammad H, Graetz, Nicholas, Guinovart, Caterina, Haagsma, Juanita, Higashi, Hideki, Kassebaum, Nicholas J, Larson, Heidi J, Lim, Stephen S, Mokdad, Ali H, Moradi-Lakeh, Maziar, Odell, Shaun V, Roth, Gregory A, Serina, Peter T, Stanaway, Jeffrey D, Misganaw, Awoke, Whiteford, Harvey A, Wolock, Timothy M, Wulf Hanson, Sarah, Abd-Allah, Foad, Abera, Semaw Ferede, Abu-Raddad, Laith J, AlBuhairan, Fadia S, Amare, Azmeraw T, Antonio, Carl Abelardo T, Artaman, Al, Barker-Collo, Suzanne L, Barrero, Lope H, Benjet, Corina, Bensenor, Isabela M, Bhutta, Zulfiqar A, Bikbov, Boris, Brazinova, Alexandra, Campos-Nonato, Ismael, Castañeda-Orjuela, Carlos A, Catalá-López, Ferrán, Chowdhury, Rajiv, Cooper, Cyrus, Crump, John A, Dandona, Rakhi, Degenhardt, Louisa, Dellavalle, Robert P, Dharmaratne, Samath D, Faraon, Emerito Jose A, Feigin, Valery L, Fürst, Thomas, Geleijnse, Johanna M, Gessner, Bradford D, Gibney, Katherine B, Goto, Atsushi, Gunnell, David, Hankey, Graeme J, Hay, Roderick J, Hornberger, John C, Hosgood, H Dean, Hu, Guoqing, Jacobsen, Kathryn H, Jayaraman, Sudha P, Jeemon, Panniyammakal, Jonas, Jost B, Karch, André, Kim, Daniel, Kim, Sungroul, Kokubo, Yoshihiro, Kuate Defo, Barthelemy, Kucuk Bicer, Burcu, Kumar, G Anil, Larsson, Anders, Leasher, Janet L, Leung, Ricky, Li, Yongmei, Lipshultz, Steven E, Lopez, Alan D, Lotufo, Paulo A, Lunevicius, Raimundas, Lyons, Ronan A, Majdan, Marek, Malekzadeh, Reza, Mashal, Taufiq, Mason-Jones, Amanda J, Melaku, Yohannes Adama, Memish, Ziad A, Mendoza, Walter, Miller, Ted R, Mock, Charles N, Murray, Joseph, Nolte, Sandra, Oh, In-Hwan, Olusanya, Bolajoko Olubukunola, Ortblad, Katrina F, Park, Eun-Kee, Paternina Caicedo, Angel J, Patten, Scott B, Patton, George C, Pereira, David M, Perico, Norberto, Piel, Frédéric B, Polinder, Suzanne, Popova, Svetlana, Pourmalek, Farshad, Quistberg, D Alex, Remuzzi, Giuseppe, Rodriguez, Alina, Rojas-Rueda, David, Rothenbacher, Dietrich, Rothstein, David H, Sanabria, Juan, Santos, Itamar S, Schwebel, David C, Sepanlou, Sadaf G, Shaheen, Amira, Shiri, Rahman, Shiue, Ivy, Skirbekk, Vegard, Sliwa, Karen, Sreeramareddy, Chandrashekhar T, Stein, Dan J, Steiner, Timothy J, Stovner, Lars Jacob, Sykes, Bryan L, Tabb, Karen M, Terkawi, Abdullah Sulieman, Thomson, Alan J, Thorne-Lyman, Andrew L, Towbin, Jeffrey Allen, Ukwaja, Kingsley Nnanna, Vasankari, Tommi, Venketasubramanian, Narayanaswamy, Vlassov, Vasiliy Victorovich, Vollset, Stein Emil, Weiderpass, Elisabete, Weintraub, Robert G, Werdecker, Andrea, Wilkinson, James D, Woldeyohannes, Solomon Meseret, Wolfe, Charles D A, Yano, Yuichiro, Yip, Paul, Yonemoto, Naohiro, Yoon, Seok-Jun, Younis, Mustafa Z, Yu, Chuanhua, El Sayed Zaki, Maysaa, Naghavi, Mohsen, Murray, Christopher J L, Vos, Theo, Kyu, Hmwe H, Pinho, Christine, Wagner, Joseph A, Brown, Jonathan C, Bertozzi-Villa, Amelia, Charlson, Fiona J, Coffeng, Luc Edgar, Dandona, Lalit, Erskine, Holly E, Ferrari, Alize J, Fitzmaurice, Christina, Fleming, Thomas D, Forouzanfar, Mohammad H, Graetz, Nicholas, Guinovart, Caterina, Haagsma, Juanita, Higashi, Hideki, Kassebaum, Nicholas J, Larson, Heidi J, Lim, Stephen S, Mokdad, Ali H, Moradi-Lakeh, Maziar, Odell, Shaun V, Roth, Gregory A, Serina, Peter T, Stanaway, Jeffrey D, Misganaw, Awoke, Whiteford, Harvey A, Wolock, Timothy M, Wulf Hanson, Sarah, Abd-Allah, Foad, Abera, Semaw Ferede, Abu-Raddad, Laith J, AlBuhairan, Fadia S, Amare, Azmeraw T, Antonio, Carl Abelardo T, Artaman, Al, Barker-Collo, Suzanne L, Barrero, Lope H, Benjet, Corina, Bensenor, Isabela M, Bhutta, Zulfiqar A, Bikbov, Boris, Brazinova, Alexandra, Campos-Nonato, Ismael, Castañeda-Orjuela, Carlos A, Catalá-López, Ferrán, Chowdhury, Rajiv, Cooper, Cyrus, Crump, John A, Dandona, Rakhi, Degenhardt, Louisa, Dellavalle, Robert P, Dharmaratne, Samath D, Faraon, Emerito Jose A, Feigin, Valery L, Fürst, Thomas, Geleijnse, Johanna M, Gessner, Bradford D, Gibney, Katherine B, Goto, Atsushi, Gunnell, David, Hankey, Graeme J, Hay, Roderick J, Hornberger, John C, Hosgood, H Dean, Hu, Guoqing, Jacobsen, Kathryn H, Jayaraman, Sudha P, Jeemon, Panniyammakal, Jonas, Jost B, Karch, André, Kim, Daniel, Kim, Sungroul, Kokubo, Yoshihiro, Kuate Defo, Barthelemy, Kucuk Bicer, Burcu, Kumar, G Anil, Larsson, Anders, Leasher, Janet L, Leung, Ricky, Li, Yongmei, Lipshultz, Steven E, Lopez, Alan D, Lotufo, Paulo A, Lunevicius, Raimundas, Lyons, Ronan A, Majdan, Marek, Malekzadeh, Reza, Mashal, Taufiq, Mason-Jones, Amanda J, Melaku, Yohannes Adama, Memish, Ziad A, Mendoza, Walter, Miller, Ted R, Mock, Charles N, Murray, Joseph, Nolte, Sandra, Oh, In-Hwan, Olusanya, Bolajoko Olubukunola, Ortblad, Katrina F, Park, Eun-Kee, Paternina Caicedo, Angel J, Patten, Scott B, Patton, George C, Pereira, David M, Perico, Norberto, Piel, Frédéric B, Polinder, Suzanne, Popova, Svetlana, Pourmalek, Farshad, Quistberg, D Alex, Remuzzi, Giuseppe, Rodriguez, Alina, Rojas-Rueda, David, Rothenbacher, Dietrich, Rothstein, David H, Sanabria, Juan, Santos, Itamar S, Schwebel, David C, Sepanlou, Sadaf G, Shaheen, Amira, Shiri, Rahman, Shiue, Ivy, Skirbekk, Vegard, Sliwa, Karen, Sreeramareddy, Chandrashekhar T, Stein, Dan J, Steiner, Timothy J, Stovner, Lars Jacob, Sykes, Bryan L, Tabb, Karen M, Terkawi, Abdullah Sulieman, Thomson, Alan J, Thorne-Lyman, Andrew L, Towbin, Jeffrey Allen, Ukwaja, Kingsley Nnanna, Vasankari, Tommi, Venketasubramanian, Narayanaswamy, Vlassov, Vasiliy Victorovich, Vollset, Stein Emil, Weiderpass, Elisabete, Weintraub, Robert G, Werdecker, Andrea, Wilkinson, James D, Woldeyohannes, Solomon Meseret, Wolfe, Charles D A, Yano, Yuichiro, Yip, Paul, Yonemoto, Naohiro, Yoon, Seok-Jun, Younis, Mustafa Z, Yu, Chuanhua, El Sayed Zaki, Maysaa, Naghavi, Mohsen, Murray, Christopher J L, and Vos, Theo

Abstract

Importance: The literature focuses on mortality among children younger than 5 years. Comparable information on nonfatal health outcomes among these children and the fatal and nonfatal burden of diseases and injuries among older children and adolescents is scarce. Objective: To determine levels and trends in the fatal and nonfatal burden of diseases and injuries among younger children (aged <5 years), older children (aged 5-9 years), and adolescents (aged 10-19 years) between 1990 and 2013 in 188 countries from the Global Burden of Disease (GBD) 2013 study. Evidence Review: Data from vital registration, verbal autopsy studies, maternal and child death surveillance, and other sources covering 14 244 site-years (ie, years of cause of death data by geography) from 1980 through 2013 were used to estimate cause-specific mortality. Data from 35 620 epidemiological sources were used to estimate the prevalence of the diseases and sequelae in the GBD 2013 study. Cause-specific mortality for most causes was estimated using the Cause of Death Ensemble Model strategy. For some infectious diseases (eg, HIV infection/AIDS, measles, hepatitis B) where the disease process is complex or the cause of death data were insufficient or unavailable, we used natural history models. For most nonfatal health outcomes, DisMod-MR 2.0, a Bayesian metaregression tool, was used to meta-analyze the epidemiological data to generate prevalence estimates. Findings: Of the 7.7 (95% uncertainty interval [UI], 7.4-8.1) million deaths among children and adolescents globally in 2013, 6.28 million occurred among younger children, 0.48 million among older children, and 0.97 million among adolescents. In 2013, the leading causes of death were lower respiratory tract infections among younger children (905 059 deaths; 95% UI, 810 304-998 125), diarrheal diseases among older children (38 325 deaths; 95% UI, 30 365-47 678), and road injuries among adolescents (115 186 deaths; 95% UI, 105 185-124 870). Iron def

Published
2016
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24. Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990-2013:quantifying the epidemiological transition

Author

Murray, Christopher J L, Barber, Ryan M, Foreman, Kyle J, Abbasoglu Ozgoren, Ayse, Abd-Allah, Foad, Abera, Semaw F, Aboyans, Victor, Abraham, Jerry P, Abubakar, Ibrahim, Abu-Raddad, Laith J, Abu-Rmeileh, Niveen M, Achoki, Tom, Ackerman, Ilana N, Ademi, Zanfina, Adou, Arsène K, Adsuar, José C, Afshin, Ashkan, Agardh, Emilie E, Alam, Sayed Saidul, Alasfoor, Deena, Albittar, Mohammed I, Alegretti, Miguel A, Alemu, Zewdie A, Alfonso-Cristancho, Rafael, Alhabib, Samia, Ali, Raghib, Alla, François, Allebeck, Peter, Almazroa, Mohammad A, Alsharif, Ubai, Alvarez, Elena, Alvis-Guzman, Nelson, Amare, Azmeraw T, Ameh, Emmanuel A, Amini, Heresh, Ammar, Walid, Anderson, H Ross, Anderson, Benjamin O, Antonio, Carl Abelardo T, Anwari, Palwasha, Arnlöv, Johan, Arsic Arsenijevic, Valentina S, Artaman, Al, Asghar, Rana J, Assadi, Reza, Atkins, Lydia S, Avila, Marco A, Awuah, Baffour, Bachman, Victoria F, Badawi, Alaa, Bahit, Maria C, Balakrishnan, Kalpana, Banerjee, Amitava, Barker-Collo, Suzanne L, Barquera, Simon, Barregard, Lars, Barrero, Lope H, Basu, Arindam, Basu, Sanjay, Basulaiman, Mohammed O, Beardsley, Justin, Bedi, Neeraj, Beghi, Ettore, Bekele, Tolesa, Bell, Michelle L, Benjet, Corina, Bennett, Derrick A, Bensenor, Isabela M, Benzian, Habib, Bernabé, Eduardo, Bertozzi-Villa, Amelia, Beyene, Tariku J, Bhala, Neeraj, Bhalla, Ashish, Bhutta, Zulfiqar A, Bienhoff, Kelly, Bikbov, Boris, Biryukov, Stan, Blore, Jed D, Blosser, Christopher D, Blyth, Fiona M, Bohensky, Megan A, Bolliger, Ian W, Bora Başara, Berrak, Bornstein, Natan M, Bose, Dipan, Boufous, Soufiane, Bourne, Rupert R A, Boyers, Lindsay N, Brainin, Michael, Brayne, Carol E, Brazinova, Alexandra, Breitborde, Nicholas J K, Brenner, Hermann, Briggs, Adam D, Brooks, Peter, Brown, Jonathan C, Brugha, Traolach S, Buchbinder, Rachelle, Buckle, Geoffrey C, Budke, Christine M, Bulchis, Anne, Bulloch, Andrew G, Campos-Nonato, Ismael R, Carabin, Hélène, Carapetis, Jonathan R, Cárdenas, Rosario, Carpenter, David O, Caso, Valeria, Castañeda-Orjuela, Carlos A, Castro, Ruben E, Catalá-López, Ferrán, Cavalleri, Fiorella, Çavlin, Alanur, Chadha, Vineet K, Chang, Jung-Chen, Charlson, Fiona J, Chen, Honglei, Chen, Wanqing, Chiang, Peggy P, Chimed-Ochir, Odgerel, Chowdhury, Rajiv, Christensen, Hanne, Christophi, Costas A, Cirillo, Massimo, Coates, Matthew M, Coffeng, Luc E, Coggeshall, Megan S, Colistro, Valentina, Colquhoun, Samantha M, Cooke, Graham S, Cooper, Cyrus, Cooper, Leslie T, Coppola, Luis M, Cortinovis, Monica, Criqui, Michael H, Crump, John A, Cuevas-Nasu, Lucia, Danawi, Hadi, Dandona, Lalit, Dandona, Rakhi, Dansereau, Emily, Dargan, Paul I, Davey, Gail, Davis, Adrian, Davitoiu, Dragos V, Dayama, Anand, De Leo, Diego, Degenhardt, Louisa, Del Pozo-Cruz, Borja, Dellavalle, Robert P, Deribe, Kebede, Derrett, Sarah, Des Jarlais, Don C, Dessalegn, Muluken, Dharmaratne, Samath D, Dherani, Mukesh K, Diaz-Torné, Cesar, Dicker, Daniel, Ding, Eric L, Dokova, Klara, Dorsey, E Ray, Driscoll, Tim R, Duan, Leilei, Duber, Herbert C, Ebel, Beth E, Edmond, Karen M, Elshrek, Yousef M, Endres, Matthias, Ermakov, Sergey P, Erskine, Holly E, Eshrati, Babak, Esteghamati, Alireza, Estep, Kara, Faraon, Emerito Jose A, Farzadfar, Farshad, Fay, Derek F, Feigin, Valery L, Felson, David T, Fereshtehnejad, Seyed-Mohammad, Fernandes, Jefferson G, Ferrari, Alize J, Fitzmaurice, Christina, Flaxman, Abraham D, Fleming, Thomas D, Foigt, Nataliya, Forouzanfar, Mohammad H, Fowkes, F Gerry R, Paleo, Urbano Fra, Franklin, Richard C, Fürst, Thomas, Gabbe, Belinda, Gaffikin, Lynne, Gankpé, Fortuné G, Geleijnse, Johanna M, Gessner, Bradford D, Gething, Peter, Gibney, Katherine B, Giroud, Maurice, Giussani, Giorgia, Gomez Dantes, Hector, Gona, Philimon, González-Medina, Diego, Gosselin, Richard A, Gotay, Carolyn C, Goto, Atsushi, Gouda, Hebe N, Graetz, Nicholas, Gugnani, Harish C, Gupta, Rahul, Gupta, Rajeev, Gutiérrez, Reyna A, Haagsma, Juanita, Hafezi-Nejad, Nima, Hagan, Holly, Halasa, Yara A, Hamadeh, Randah R, Hamavid, Hannah, Hammami, Mouhanad, Hancock, Jamie, Hankey, Graeme J, Hansen, Gillian M, Hao, Yuantao, Harb, Hilda L, Haro, Josep Maria, Havmøller, Rasmus, Hay, Simon I, Hay, Roderick J, Heredia-Pi, Ileana B, Heuton, Kyle R, Heydarpour, Pouria, Higashi, Hideki, Hijar, Martha, Hoek, Hans W, Hoffman, Howard J, Hosgood, H Dean, Hossain, Mazeda, Hotez, Peter J, Hoy, Damian G, Hsairi, Mohamed, Hu, Guoqing, Huang, Cheng, Huang, John J, Husseini, Abdullatif, Huynh, Chantal, Iannarone, Marissa L, Iburg, Kim Moesgaard, Innos, Kaire, Inoue, Manami, Islami, Farhad, Jacobsen, Kathryn H, Jarvis, Deborah L, Jassal, Simerjot K, Jee, Sun Ha, Jeemon, Panniyammakal, Jensen, Paul N, Jha, Vivekanand, Jiang, Guohong, Jiang, Ying, Jonas, Jost B, Juel, Knud, Kan, Haidong, Karch, André, Karema, Corine K, Karimkhani, Chante, Karthikeyan, Ganesan, Kassebaum, Nicholas J, Kaul, Anil, Kawakami, Norito, Kazanjan, Konstantin, Kemp, Andrew H, Kengne, Andre P, Keren, Andre, Khader, Yousef S, Khalifa, Shams Eldin A, Khan, Ejaz A, Khan, Gulfaraz, Khang, Young-Ho, Kieling, Christian, Kim, Daniel, Kim, Sungroul, Kim, Yunjin, Kinfu, Yohannes, Kinge, Jonas M, Kivipelto, Miia, Knibbs, Luke D, Knudsen, Ann Kristin, Kokubo, Yoshihiro, Kosen, Soewarta, Krishnaswami, Sanjay, Kuate Defo, Barthelemy, Kucuk Bicer, Burcu, Kuipers, Ernst J, Kulkarni, Chanda, Kulkarni, Veena S, Kumar, G Anil, Kyu, Hmwe H, Lai, Taavi, Lalloo, Ratilal, Lallukka, Tea, Lam, Hilton, Lan, Qing, Lansingh, Van C, Larsson, Anders, Lawrynowicz, Alicia E B, Leasher, Janet L, Leigh, James, Leung, Ricky, Levitz, Carly E, Li, Bin, Li, Yichong, Li, Yongmei, Lim, Stephen S, Lind, Maggie, Lipshultz, Steven E, Liu, Shiwei, Liu, Yang, Lloyd, Belinda K, Lofgren, Katherine T, Logroscino, Giancarlo, Looker, Katharine J, Lortet-Tieulent, Joannie, Lotufo, Paulo A, Lozano, Rafael, Lucas, Robyn M, Lunevicius, Raimundas, Lyons, Ronan A, Ma, Stefan, Macintyre, Michael F, Mackay, Mark T, Majdan, Marek, Malekzadeh, Reza, Marcenes, Wagner, Margolis, David J, Margono, Christopher, Marzan, Melvin B, Masci, Joseph R, Mashal, Mohammad T, Matzopoulos, Richard, Mayosi, Bongani M, Mazorodze, Tasara T, Mcgill, Neil W, Mcgrath, John J, Mckee, Martin, Mclain, Abigail, Meaney, Peter A, Medina, Catalina, Mehndiratta, Man Mohan, Mekonnen, Wubegzier, Melaku, Yohannes A, Meltzer, Michele, Memish, Ziad A, Mensah, George A, Meretoja, Atte, Mhimbira, Francis A, Micha, Renata, Miller, Ted R, Mills, Edward J, Mitchell, Philip B, Mock, Charles N, Mohamed Ibrahim, Norlinah, Mohammad, Karzan A, Mokdad, Ali H, Mola, Glen L D, Monasta, Lorenzo, Montañez Hernandez, Julio C, Montico, Marcella, Montine, Thomas J, Mooney, Meghan D, Moore, Ami R, Moradi-Lakeh, Maziar, Moran, Andrew E, Mori, Rintaro, Moschandreas, Joanna, Moturi, Wilkister N, Moyer, Madeline L, Mozaffarian, Dariush, Msemburi, William T, Mueller, Ulrich O, Mukaigawara, Mitsuru, Mullany, Erin C, Murdoch, Michele E, Murray, Joseph, Murthy, Kinnari S, Naghavi, Mohsen, Naheed, Aliya, Naidoo, Kovin S, Naldi, 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Carlos A, Castro, Ruben E, Catalá-López, Ferrán, Cavalleri, Fiorella, Çavlin, Alanur, Chadha, Vineet K, Chang, Jung-Chen, Charlson, Fiona J, Chen, Honglei, Chen, Wanqing, Chiang, Peggy P, Chimed-Ochir, Odgerel, Chowdhury, Rajiv, Christensen, Hanne, Christophi, Costas A, Cirillo, Massimo, Coates, Matthew M, Coffeng, Luc E, Coggeshall, Megan S, Colistro, Valentina, Colquhoun, Samantha M, Cooke, Graham S, Cooper, Cyrus, Cooper, Leslie T, Coppola, Luis M, Cortinovis, Monica, Criqui, Michael H, Crump, John A, Cuevas-Nasu, Lucia, Danawi, Hadi, Dandona, Lalit, Dandona, Rakhi, Dansereau, Emily, Dargan, Paul I, Davey, Gail, Davis, Adrian, Davitoiu, Dragos V, Dayama, Anand, De Leo, Diego, Degenhardt, Louisa, Del Pozo-Cruz, Borja, Dellavalle, Robert P, Deribe, Kebede, Derrett, Sarah, Des Jarlais, Don C, Dessalegn, Muluken, Dharmaratne, Samath D, Dherani, Mukesh K, Diaz-Torné, Cesar, Dicker, Daniel, Ding, Eric L, Dokova, Klara, Dorsey, E Ray, Driscoll, Tim R, Duan, Leilei, Duber, Herbert C, Ebel, 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Marzan, Melvin B, Masci, Joseph R, Mashal, Mohammad T, Matzopoulos, Richard, Mayosi, Bongani M, Mazorodze, Tasara T, Mcgill, Neil W, Mcgrath, John J, Mckee, Martin, Mclain, Abigail, Meaney, Peter A, Medina, Catalina, Mehndiratta, Man Mohan, Mekonnen, Wubegzier, Melaku, Yohannes A, Meltzer, Michele, Memish, Ziad A, Mensah, George A, Meretoja, Atte, Mhimbira, Francis A, Micha, Renata, Miller, Ted R, Mills, Edward J, Mitchell, Philip B, Mock, Charles N, Mohamed Ibrahim, Norlinah, Mohammad, Karzan A, Mokdad, Ali H, Mola, Glen L D, Monasta, Lorenzo, Montañez Hernandez, Julio C, Montico, Marcella, Montine, Thomas J, Mooney, Meghan D, Moore, Ami R, Moradi-Lakeh, Maziar, Moran, Andrew E, Mori, Rintaro, Moschandreas, Joanna, Moturi, Wilkister N, Moyer, Madeline L, Mozaffarian, Dariush, Msemburi, William T, Mueller, Ulrich O, Mukaigawara, Mitsuru, Mullany, Erin C, Murdoch, Michele E, Murray, Joseph, Murthy, Kinnari S, Naghavi, Mohsen, Naheed, Aliya, Naidoo, Kovin S, Naldi, Luigi, Nand, Devina, Nangia, Vinay, Narayan, K M Venkat, Nejjari, Chakib, Neupane, Sudan P, Newton, Charles R, Ng, Marie, Ngalesoni, Frida N, Nguyen, Grant, Nisar, Muhammad I, Nolte, Sandra, Norheim, Ole F, Norman, Rosana E, Norrving, Bo, Nyakarahuka, Luke, Oh, In-Hwan, Ohkubo, Takayoshi, Ohno, Summer L, Olusanya, Bolajoko O, Opio, John Nelson, Ortblad, Katrina, Ortiz, Alberto, Pain, Amanda W, Pandian, Jeyaraj D, Panelo, Carlo Irwin A, Papachristou, Christina, Park, Eun-Kee, Park, Jae-Hyun, Patten, Scott B, Patton, George C, Paul, Vinod K, Pavlin, Boris I, Pearce, Neil, Pereira, David M, Perez-Padilla, Rogelio, Perez-Ruiz, Fernando, Perico, Norberto, Pervaiz, Aslam, Pesudovs, Konrad, Peterson, Carrie B, Petzold, Max, Phillips, Michael R, Phillips, Bryan K, Phillips, David E, Piel, Frédéric B, Plass, Dietrich, Poenaru, Dan, Polinder, Suzanne, Pope, Daniel, Popova, Svetlana, Poulton, Richie G, Pourmalek, Farshad, Prabhakaran, Dorairaj, Prasad, Noela M, Pullan, Rachel L, Qato, Dima M, Quistberg, D Alex, 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Silberberg, Donald H, Simard, Edgar P, Sindi, Shireen, Singh, Abhishek, Singh, Jasvinder A, Singh, Lavanya, Skirbekk, Vegard, Slepak, Erica Leigh, Sliwa, Karen, Soneji, Samir, Søreide, Kjetil, Soshnikov, Sergey, Sposato, Luciano A, Sreeramareddy, Chandrashekhar T, Stanaway, Jeffrey D, Stathopoulou, Vasiliki, Stein, Dan J, Stein, Murray B, Steiner, Caitlyn, Steiner, Timothy J, Stevens, Antony, Stewart, Andrea, Stovner, Lars J, Stroumpoulis, Konstantinos, Sunguya, Bruno F, Swaminathan, Soumya, Swaroop, Mamta, Sykes, Bryan L, Tabb, Karen M, Takahashi, Ken, Tandon, Nikhil, Tanne, David, Tanner, Marcel, Tavakkoli, Mohammad, Taylor, Hugh R, Te Ao, Braden J, Tediosi, Fabrizio, Temesgen, Awoke M, Templin, Tara, Ten Have, Margreet, Tenkorang, Eric Y, Terkawi, Abdullah S, Thomson, Blake, Thorne-Lyman, Andrew L, Thrift, Amanda G, Thurston, George D, Tillmann, Taavi, Tonelli, Marcello, Topouzis, Fotis, Toyoshima, Hideaki, Traebert, Jefferson, Tran, Bach X, Trillini, Matias, Truelsen, Thomas, Tsilimbaris, Miltiadis, Tuzcu, Emin M, Uchendu, Uche S, Ukwaja, Kingsley N, Undurraga, Eduardo A, Uzun, Selen B, Van Brakel, Wim H, Van De Vijver, Steven, van Gool, Coen H, Van Os, Jim, Vasankari, Tommi J, Venketasubramanian, N, Violante, Francesco S, Vlassov, Vasiliy V, Vollset, Stein Emil, Wagner, Gregory R, Wagner, Joseph, Waller, Stephen G, Wan, Xia, Wang, Haidong, Wang, Jianli, Wang, Linhong, Warouw, Tati S, Weichenthal, Scott, Weiderpass, Elisabete, Weintraub, Robert G, Wenzhi, Wang, Werdecker, Andrea, Westerman, Ronny, Whiteford, Harvey A, Wilkinson, James D, Williams, Thomas N, Wolfe, Charles D, Wolock, Timothy M, Woolf, Anthony D, Wulf, Sarah, Wurtz, Brittany, Xu, Gelin, Yan, Lijing L, Yano, Yuichiro, Ye, Pengpeng, Yentür, Gökalp K, Yip, Paul, Yonemoto, Naohiro, Yoon, Seok-Jun, Younis, Mustafa Z, Yu, Chuanhua, Zaki, Maysaa E, Zhao, Yong, Zheng, Yingfeng, Zonies, David, Zou, Xiaonong, Salomon, Joshua A, Lopez, Alan D, and Vos, Theo

Abstract

BACKGROUND: The Global Burden of Disease Study 2013 (GBD 2013) aims to bring together all available epidemiological data using a coherent measurement framework, standardised estimation methods, and transparent data sources to enable comparisons of health loss over time and across causes, age-sex groups, and countries. The GBD can be used to generate summary measures such as disability-adjusted life-years (DALYs) and healthy life expectancy (HALE) that make possible comparative assessments of broad epidemiological patterns across countries and time. These summary measures can also be used to quantify the component of variation in epidemiology that is related to sociodemographic development.METHODS: We used the published GBD 2013 data for age-specific mortality, years of life lost due to premature mortality (YLLs), and years lived with disability (YLDs) to calculate DALYs and HALE for 1990, 1995, 2000, 2005, 2010, and 2013 for 188 countries. We calculated HALE using the Sullivan method; 95% uncertainty intervals (UIs) represent uncertainty in age-specific death rates and YLDs per person for each country, age, sex, and year. We estimated DALYs for 306 causes for each country as the sum of YLLs and YLDs; 95% UIs represent uncertainty in YLL and YLD rates. We quantified patterns of the epidemiological transition with a composite indicator of sociodemographic status, which we constructed from income per person, average years of schooling after age 15 years, and the total fertility rate and mean age of the population. We applied hierarchical regression to DALY rates by cause across countries to decompose variance related to the sociodemographic status variable, country, and time.FINDINGS: Worldwide, from 1990 to 2013, life expectancy at birth rose by 6·2 years (95% UI 5·6-6·6), from 65·3 years (65·0-65·6) in 1990 to 71·5 years (71·0-71·9) in 2013, HALE at birth rose by 5·4 years (4·9-5·8), from 56·9 years (54·5-59·1) to 62·3 years (59·7-64·8), total DALYs

Published
2015

26. Global and national Burden of diseases and injuries among children and adolescents between 1990 and 2013

Author

Kyu, Hmwe H., Pinho, Christine, Wagner, Joseph A., Brown, Jonathan C., Bertozzi-Villa, Amelia, Charlson, Fiona J., Coffeng, Luc Edgar, Dandona, Lalit, Erskine, Holly E., Ferrari, Alize J., Fitzmaurice, Christina, Fleming, Thomas D., Forouzanfar, Mohammad H., Graetz, Nicholas, Guinovart, Caterina, Haagsma, Juanita, Higashi, Hideki, Kassebaum, Nicholas J., Larson, Heidi J., Lim, Stephen S., Mokdad, Ali H., Moradi-Lakeh, Maziar, Odell, Shaun V., Roth, Gregory A., Serina, Peter T., Stanaway, Jeffrey D., Misganaw, Awoke, Whiteford, Harvey A., Wolock, Timothy M., Wulf Hanson, Sarah, Abd-Allah, Foad, Abera, Semaw Ferede, Abu-Raddad, Laith J., AlBuhairan, Fadia S., Amare, Azmeraw T., Antonio, Carl Abelardo T., Artaman, Al, Barker-Collo, Suzanne L., Barrero, Lope H., Benjet, Corina, Bensenor, Isabela M., Bhutta, Zulfiqar A., Bikbov, Boris, Brazinova, Alexandra, Campos-Nonato, Ismael, Castañeda-Orjuela, Carlos A., Catalá-López, Ferrán, Chowdhury, Rajiv, Cooper, Cyrus, Crump, John A., Dandona, Rakhi, Degenhardt, Louisa, Dellavalle, Robert P., Dharmaratne, Samath D., Faraon, Emerito Jose A., Feigin, Valery L., Fürst, Thomas, Geleijnse, Johanna M., Gessner, Bradford D., Gibney, Katherine B., Goto, Atsushi, Gunnell, David, Hankey, Graeme J., Hay, Roderick J., Hornberger, John C., Hosgood, H. Dean, Hu, Guoqing, Jacobsen, Kathryn H., Jayaraman, Sudha P., Jeemon, Panniyammakal, Jonas, Jost B., Karch, André, Kim, Daniel, Kim, Sungroul, Kokubo, Yoshihiro, Kuate Defo, Barthelemy, Kucuk Bicer, Burcu, Kumar, G. Anil, Larsson, Anders, Leasher, Janet L., Leung, Ricky, Li, Yongmei, Lipshultz, Steven E., Lopez, Alan D., Lotufo, Paulo A., Lunevicius, Raimundas, Lyons, Ronan A., Majdan, Marek, Malekzadeh, Reza, Mashal, Taufiq, Mason-Jones, Amanda J., Melaku, Yohannes Adama, Memish, Ziad A., Mendoza, Walter, Miller, Ted R., Mock, Charles N., Murray, Joseph, Nolte, Sandra, Oh, In-Hwan, Olusanya, Bolajoko Olubukunola, Ortblad, Katrina F., Park, Eun-Kee, Paternina Caicedo, Angel J., Patten, Scott B., Patton, George C., Pereira, David M., Perico, Norberto, Piel, Frédéric B., Polinder, Suzanne, Popova, Svetlana, Pourmalek, Farshad, Quistberg, D. Alex, Remuzzi, Giuseppe, Rodriguez, Alina, Rojas-Rueda, David, Rothenbacher, Dietrich, Rothstein, David H., Sanabria, Juan, Santos, Itamar S., Schwebel, David C., Sepanlou, Sadaf G., Shaheen, Amira, Shiri, Rahman, Shiue, Ivy, Skirbekk, Vegard, Sliwa, Karen, Sreeramareddy, Chandrashekhar T., Stein, Dan J., Steiner, Timothy J., Stovner, Lars Jacob, Sykes, Bryan L., Tabb, Karen M., Terkawi, Abdullah Sulieman, Thomson, Alan J., Thorne-Lyman, Andrew L., Towbin, Jeffrey Allen, Ukwaja, Kingsley Nnanna, Vasankari, Tommi, Venketasubramanian, Narayanaswamy, Vlassov, Vasiliy Victorovich, Vollset, Stein Emil, Weiderpass, Elisabete, Weintraub, Robert G., Werdecker, Andrea, Wilkinson, James D., Woldeyohannes, Solomon Meseret, Wolfe, Charles D. A., Yano, Yuichiro, Yip, Paul, Yonemoto, Naohiro, Yoon, Seok-Jun, Younis, Mustafa Z., Yu, Chuanhua, El Sayed Zaki, Maysaa, Naghavi, Mohsen, Murray, Christopher J. L., Vos, Theo, Kyu, Hmwe H., Pinho, Christine, Wagner, Joseph A., Brown, Jonathan C., Bertozzi-Villa, Amelia, Charlson, Fiona J., Coffeng, Luc Edgar, Dandona, Lalit, Erskine, Holly E., Ferrari, Alize J., Fitzmaurice, Christina, Fleming, Thomas D., Forouzanfar, Mohammad H., Graetz, Nicholas, Guinovart, Caterina, Haagsma, Juanita, Higashi, Hideki, Kassebaum, Nicholas J., Larson, Heidi J., Lim, Stephen S., Mokdad, Ali H., Moradi-Lakeh, Maziar, Odell, Shaun V., Roth, Gregory A., Serina, Peter T., Stanaway, Jeffrey D., Misganaw, Awoke, Whiteford, Harvey A., Wolock, Timothy M., Wulf Hanson, Sarah, Abd-Allah, Foad, Abera, Semaw Ferede, Abu-Raddad, Laith J., AlBuhairan, Fadia S., Amare, Azmeraw T., Antonio, Carl Abelardo T., Artaman, Al, Barker-Collo, Suzanne L., Barrero, Lope H., Benjet, Corina, Bensenor, Isabela M., Bhutta, Zulfiqar A., Bikbov, Boris, Brazinova, Alexandra, Campos-Nonato, Ismael, Castañeda-Orjuela, Carlos A., Catalá-López, Ferrán, Chowdhury, Rajiv, Cooper, Cyrus, Crump, John A., Dandona, Rakhi, Degenhardt, Louisa, Dellavalle, Robert P., Dharmaratne, Samath D., Faraon, Emerito Jose A., Feigin, Valery L., Fürst, Thomas, Geleijnse, Johanna M., Gessner, Bradford D., Gibney, Katherine B., Goto, Atsushi, Gunnell, David, Hankey, Graeme J., Hay, Roderick J., Hornberger, John C., Hosgood, H. Dean, Hu, Guoqing, Jacobsen, Kathryn H., Jayaraman, Sudha P., Jeemon, Panniyammakal, Jonas, Jost B., Karch, André, Kim, Daniel, Kim, Sungroul, Kokubo, Yoshihiro, Kuate Defo, Barthelemy, Kucuk Bicer, Burcu, Kumar, G. Anil, Larsson, Anders, Leasher, Janet L., Leung, Ricky, Li, Yongmei, Lipshultz, Steven E., Lopez, Alan D., Lotufo, Paulo A., Lunevicius, Raimundas, Lyons, Ronan A., Majdan, Marek, Malekzadeh, Reza, Mashal, Taufiq, Mason-Jones, Amanda J., Melaku, Yohannes Adama, Memish, Ziad A., Mendoza, Walter, Miller, Ted R., Mock, Charles N., Murray, Joseph, Nolte, Sandra, Oh, In-Hwan, Olusanya, Bolajoko Olubukunola, Ortblad, Katrina F., Park, Eun-Kee, Paternina Caicedo, Angel J., Patten, Scott B., Patton, George C., Pereira, David M., Perico, Norberto, Piel, Frédéric B., Polinder, Suzanne, Popova, Svetlana, Pourmalek, Farshad, Quistberg, D. Alex, Remuzzi, Giuseppe, Rodriguez, Alina, Rojas-Rueda, David, Rothenbacher, Dietrich, Rothstein, David H., Sanabria, Juan, Santos, Itamar S., Schwebel, David C., Sepanlou, Sadaf G., Shaheen, Amira, Shiri, Rahman, Shiue, Ivy, Skirbekk, Vegard, Sliwa, Karen, Sreeramareddy, Chandrashekhar T., Stein, Dan J., Steiner, Timothy J., Stovner, Lars Jacob, Sykes, Bryan L., Tabb, Karen M., Terkawi, Abdullah Sulieman, Thomson, Alan J., Thorne-Lyman, Andrew L., Towbin, Jeffrey Allen, Ukwaja, Kingsley Nnanna, Vasankari, Tommi, Venketasubramanian, Narayanaswamy, Vlassov, Vasiliy Victorovich, Vollset, Stein Emil, Weiderpass, Elisabete, Weintraub, Robert G., Werdecker, Andrea, Wilkinson, James D., Woldeyohannes, Solomon Meseret, Wolfe, Charles D. A., Yano, Yuichiro, Yip, Paul, Yonemoto, Naohiro, Yoon, Seok-Jun, Younis, Mustafa Z., Yu, Chuanhua, El Sayed Zaki, Maysaa, Naghavi, Mohsen, Murray, Christopher J. L., and Vos, Theo

Abstract

Importance The literature focuses on mortality among children younger than 5 years. Comparable information on nonfatal health outcomes among these children and the fatal and nonfatal burden of diseases and injuries among older children and adolescents is scarce. Objective To determine levels and trends in the fatal and nonfatal burden of diseases and injuries among younger children (aged <5 years), older children (aged 5-9 years), and adolescents (aged 10-19 years) between 1990 and 2013 in 188 countries from the Global Burden of Disease (GBD) 2013 study. Evidence Review Data from vital registration, verbal autopsy studies, maternal and child death surveillance, and other sources covering 14 244 site-years (ie, years of cause of death data by geography) from 1980 through 2013 were used to estimate cause-specific mortality. Data from 35 620 epidemiological sources were used to estimate the prevalence of the diseases and sequelae in the GBD 2013 study. Cause-specific mortality for most causes was estimated using the Cause of Death Ensemble Model strategy. For some infectious diseases (eg, HIV infection/AIDS, measles, hepatitis B) where the disease process is complex or the cause of death data were insufficient or unavailable, we used natural history models. For most nonfatal health outcomes, DisMod-MR 2.0, a Bayesian metaregression tool, was used to meta-analyze the epidemiological data to generate prevalence estimates. Findings Of the 7.7 (95% uncertainty interval [UI], 7.4-8.1) million deaths among children and adolescents globally in 2013, 6.28 million occurred among younger children, 0.48 million among older children, and 0.97 million among adolescents. In 2013, the leading causes of death were lower respiratory tract infections among younger children (905 059 deaths; 95% UI, 810 304-998 125), diarrheal diseases among older children (38 325 deaths; 95% UI, 30 365-47 678), and road injuries among adolescents (115 186 deaths; 95% UI, 105 185-124 870). Iron deficiency

27. Emergency department care transition barriers: A qualitative study of care partners of older adults with cognitive impairment.

Author

Gettel CJ, Serina PT, Uzamere I, Hernandez-Bigos K, Venkatesh AK, Cohen AB, Monin JK, Feder SL, Fried TR, and Hwang U

Abstract

Introduction: After emergency department (ED) discharge, persons living with cognitive impairment (PLWCI) and their care partners are particularly at risk for adverse outcomes. We sought to identify the barriers experienced by care partners of PLWCI during ED discharge care transitions., Methods: We conducted a qualitative study of 25 care partners of PLWCI discharged from four EDs. We used the validated 4AT and care partner-completed AD8 screening tools, respectively, to exclude care partners of older adults with concern for delirium and include care partners of older adults with cognitive impairment. We conducted recorded, semi-structured interviews using a standardized guide, and two team members coded and analyzed all professional transcriptions to identify emerging themes and representative quotations., Results: Care partners' mean age was 56.7 years, 80% were female, and 24% identified as African American. We identified four major barriers regarding ED discharge care transitions among care partners of PLWCI: (1) unique care considerations while in the ED setting impact the perceived success of the care transition, (2) poor communication and lack of care partner engagement was a commonplace during the ED discharge process, (3) care partners experienced challenges and additional responsibilities when aiding during acute illness and recovery phases, and (4) navigating the health care system after an ED encounter was perceived as difficult by care partners., Discussion: Our findings demonstrate critical barriers faced during ED discharge care transitions among care partners of PLWCI. Findings from this work may inform the development of novel care partner-reported outcome measures as well as ED discharge care transition interventions targeting care partners., Competing Interests: The authors declare no conflicts of interest., (© 2022 The Authors. Alzheimer's & Dementia: Translational Research & Clinical Interventions published by Wiley Periodicals LLC on behalf of Alzheimer's Association.)

Published
2022
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28. Use of Smartphone for Verbal Autopsy.

Author

Zhao Y, Joshi R, Rampatige R, Sun J, Huang L, Chen S, Wu R, Neal B, Lopez AD, Stewart AL, Serina PT, Li C, Zhang J, Zhang J, Zhang Y, and Yan LL

Subjects
Adult, Cause of Death, China epidemiology, Costs and Cost Analysis, Feasibility Studies, Female, Humans, Male, Pilot Projects, Autopsy methods, Interviews as Topic methods, Rural Population, Smartphone statistics & numerical data
Abstract

Traditionally, verbal autopsies (VA) are collected on paper-based questionnaires and reviewed by physicians for cause of death assignment, it is resource intensive and time consuming. The Population Health Metrics Research Consortium VA questionnaires was made available on an Android-based application and cause of death was derived using the Tariff method. Over one year, all adult deaths occurring in 48 villages in 4 counties were identified and a VA interview was conducted using the smartphone VA application. A total of 507 adult deaths were recorded and VA interviews were conducted. Cardiovascular disease was the leading cause of death (35.3%) followed by injury (14.6%) and neoplasms (13.5%). The total cost of the pilot study was USD28 835 (USD0.42 per capita). The interviewers found use of smartphones to conduct interviews to be easier. The study showed that using a smartphone application for VA interviews was feasible for implementation in rural China.

Published
2016
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29. Global and National Burden of Diseases and Injuries Among Children and Adolescents Between 1990 and 2013: Findings From the Global Burden of Disease 2013 Study.

Author

Kyu HH, Pinho C, Wagner JA, Brown JC, Bertozzi-Villa A, Charlson FJ, Coffeng LE, Dandona L, Erskine HE, Ferrari AJ, Fitzmaurice C, Fleming TD, Forouzanfar MH, Graetz N, Guinovart C, Haagsma J, Higashi H, Kassebaum NJ, Larson HJ, Lim SS, Mokdad AH, Moradi-Lakeh M, Odell SV, Roth GA, Serina PT, Stanaway JD, Misganaw A, Whiteford HA, Wolock TM, Wulf Hanson S, Abd-Allah F, Abera SF, Abu-Raddad LJ, AlBuhairan FS, Amare AT, Antonio CA, Artaman A, Barker-Collo SL, Barrero LH, Benjet C, Bensenor IM, Bhutta ZA, Bikbov B, Brazinova A, Campos-Nonato I, Castañeda-Orjuela CA, Catalá-López F, Chowdhury R, Cooper C, Crump JA, Dandona R, Degenhardt L, Dellavalle RP, Dharmaratne SD, Faraon EJ, Feigin VL, Fürst T, Geleijnse JM, Gessner BD, Gibney KB, Goto A, Gunnell D, Hankey GJ, Hay RJ, Hornberger JC, Hosgood HD, Hu G, Jacobsen KH, Jayaraman SP, Jeemon P, Jonas JB, Karch A, Kim D, Kim S, Kokubo Y, Kuate Defo B, Kucuk Bicer B, Kumar GA, Larsson A, Leasher JL, Leung R, Li Y, Lipshultz SE, Lopez AD, Lotufo PA, Lunevicius R, Lyons RA, Majdan M, Malekzadeh R, Mashal T, Mason-Jones AJ, Melaku YA, Memish ZA, Mendoza W, Miller TR, Mock CN, Murray J, Nolte S, Oh IH, Olusanya BO, Ortblad KF, Park EK, Paternina Caicedo AJ, Patten SB, Patton GC, Pereira DM, Perico N, Piel FB, Polinder S, Popova S, Pourmalek F, Quistberg DA, Remuzzi G, Rodriguez A, Rojas-Rueda D, Rothenbacher D, Rothstein DH, Sanabria J, Santos IS, Schwebel DC, Sepanlou SG, Shaheen A, Shiri R, Shiue I, Skirbekk V, Sliwa K, Sreeramareddy CT, Stein DJ, Steiner TJ, Stovner LJ, Sykes BL, Tabb KM, Terkawi AS, Thomson AJ, Thorne-Lyman AL, Towbin JA, Ukwaja KN, Vasankari T, Venketasubramanian N, Vlassov VV, Vollset SE, Weiderpass E, Weintraub RG, Werdecker A, Wilkinson JD, Woldeyohannes SM, Wolfe CD, Yano Y, Yip P, Yonemoto N, Yoon SJ, Younis MZ, Yu C, El Sayed Zaki M, Naghavi M, Murray CJ, and Vos T

Subjects
Adolescent, Adolescent Health statistics & numerical data, Bayes Theorem, Child, Child Health statistics & numerical data, Child Mortality trends, Child, Preschool, Female, Global Health statistics & numerical data, Humans, Male, Prevalence, Public Health Surveillance, Quality-Adjusted Life Years, Adolescent Health trends, Child Health trends, Cost of Illness, Developed Countries statistics & numerical data, Developing Countries statistics & numerical data, Global Health trends, Wounds and Injuries epidemiology
Abstract

Importance: The literature focuses on mortality among children younger than 5 years. Comparable information on nonfatal health outcomes among these children and the fatal and nonfatal burden of diseases and injuries among older children and adolescents is scarce., Objective: To determine levels and trends in the fatal and nonfatal burden of diseases and injuries among younger children (aged <5 years), older children (aged 5-9 years), and adolescents (aged 10-19 years) between 1990 and 2013 in 188 countries from the Global Burden of Disease (GBD) 2013 study., Evidence Review: Data from vital registration, verbal autopsy studies, maternal and child death surveillance, and other sources covering 14,244 site-years (ie, years of cause of death data by geography) from 1980 through 2013 were used to estimate cause-specific mortality. Data from 35,620 epidemiological sources were used to estimate the prevalence of the diseases and sequelae in the GBD 2013 study. Cause-specific mortality for most causes was estimated using the Cause of Death Ensemble Model strategy. For some infectious diseases (eg, HIV infection/AIDS, measles, hepatitis B) where the disease process is complex or the cause of death data were insufficient or unavailable, we used natural history models. For most nonfatal health outcomes, DisMod-MR 2.0, a Bayesian metaregression tool, was used to meta-analyze the epidemiological data to generate prevalence estimates., Findings: Of the 7.7 (95% uncertainty interval [UI], 7.4-8.1) million deaths among children and adolescents globally in 2013, 6.28 million occurred among younger children, 0.48 million among older children, and 0.97 million among adolescents. In 2013, the leading causes of death were lower respiratory tract infections among younger children (905.059 deaths; 95% UI, 810,304-998,125), diarrheal diseases among older children (38,325 deaths; 95% UI, 30,365-47,678), and road injuries among adolescents (115,186 deaths; 95% UI, 105,185-124,870). Iron deficiency anemia was the leading cause of years lived with disability among children and adolescents, affecting 619 (95% UI, 618-621) million in 2013. Large between-country variations exist in mortality from leading causes among children and adolescents. Countries with rapid declines in all-cause mortality between 1990 and 2013 also experienced large declines in most leading causes of death, whereas countries with the slowest declines had stagnant or increasing trends in the leading causes of death. In 2013, Nigeria had a 12% global share of deaths from lower respiratory tract infections and a 38% global share of deaths from malaria. India had 33% of the world's deaths from neonatal encephalopathy. Half of the world's diarrheal deaths among children and adolescents occurred in just 5 countries: India, Democratic Republic of the Congo, Pakistan, Nigeria, and Ethiopia., Conclusions and Relevance: Understanding the levels and trends of the leading causes of death and disability among children and adolescents is critical to guide investment and inform policies. Monitoring these trends over time is also key to understanding where interventions are having an impact. Proven interventions exist to prevent or treat the leading causes of unnecessary death and disability among children and adolescents. The findings presented here show that these are underused and give guidance to policy makers in countries where more attention is needed., Competing Interests: Conflict of Interest Disclosures: Dr. Kassebaum reports personal fees and non-financial support from Vifor Pharmaceuticals, Axon Communications LLC and Merck & Co outside the submitted work. KPG was awarded the NHMRC-Gustav Nossal Postgraduate Award sponsored by CSL; this award is peer reviewed and CSL had no part in selecting the awardee. Prof. Lotufo reports honoraria (modest) from Abbvie for one lecture. Walter Mendoza is program analyst at the UNFPA country office in Peru, which not necessarily endorses the study. Prof. Santos reports receiving a grant from São Paulo Research Foundation/FAPESP (Brazilian governmental research agency) for research purposes. In the past 3 years, Dr. Stein has received research grants and/or consultancy honoraria from AMBRF, Biocodex, Cipla, Lundbeck, National Responsible Gambling Foundation, Novartis, Servier, and Sun. No other conflicts are reported.

Published
2016
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30. Identifying otolaryngology systematic review research gaps: comparing Global Burden of Disease 2010 results with Cochrane Database of Systematic Review content.

Author

Pederson H, Okland T, Boyers LN, Karimkhani C, Rosenfeld RM, Nasser M, Yoong SL, Wolfenden L, Kyu HH, Serina PT, Coggeshall M, and Dellavalle RP

Subjects
Humans, Cost of Illness, Databases, Factual, Otorhinolaryngologic Diseases epidemiology, Systematic Reviews as Topic
Abstract

Importance: Burden of disease should inform research prioritization., Objective: To determine whether systematic reviews and protocols published in the Cochrane Database of Systematic Reviews (CDSR) appropriately reflect disease burden for otolaryngologic conditions as measured by the Global Burden of Disease (GBD) 2010 project., Design: Two investigators independently assessed 10 otolaryngologic conditions in CDSR for systematic review and protocol representation from March to June 2014. The otolaryngologic diseases were matched to their respective GBD 2010 disability-adjusted life-years (DALYs) to assess their correlation., Main Outcomes and Measures: Relationship of CDSR representation (based on systematic reviews and protocols) with percentage of total 2010 DALYs, 2010 DALY rank, and DALY percentage change from 1990 to 2010 for 10 otolaryngologic conditions., Results: All 10 otolaryngologic conditions were represented by at least 1 systematic review in CDSR. The number of reviews and protocols in CDSR was well matched with GBD 2010 disability metrics for only 1 disease, mouth cancer. Upper respiratory infections, otitis media, thyroid cancer, and cleft lip and cleft palate were overrepresented in CDSR, and esophageal cancer, "other hearing loss," nasopharynx cancer, larynx cancer, and "cancer of other part of pharynx and oropharynx" were underrepresented., Conclusions and Relevance: The representation of otolaryngologic conditions in CDSR correlates poorly with DALY metrics. The results of this study may guide future research prioritization and allocation of funds.

Published
2015
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