214 results on '"Serik, S."'
Search Results
2. Promotion of Rapeseed to the Southern Regions of Kazakhstan by Creating Varieties of Winter Type
- Author
-
Meiirman, Galiolla T., primary, Yerzhanova, Sakysh T., additional, Abayev, Serik S., additional, Bastaubayeva, Sholpan O., additional, Ainebekova, Bakyt A., additional, Kenebayev, Amankeldi T., additional, and Shegebayev, Galym O., additional
- Published
- 2023
- Full Text
- View/download PDF
3. Mathematical modeling of the aerodynamic coefficients of a sail blade
- Author
-
Akmaral Zh. Tleubergenova, Nazgul K. Tanasheva, Kulzhan M. Shaimerdenova, Serik S. Kassymov, Asem R. Bakhtybekova, Nurgul N. Shuyushbayeva, Saule Zh. Uzbergenova, and Gulden A. Ranova
- Subjects
Sail blade ,Wind turbine ,Modeling ,ANSYS FLUENT ,Aerodynamic coefficients ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Motor vehicles. Aeronautics. Astronautics ,TL1-4050 - Abstract
Abstract The authors of the work numerically studied the aerodynamic coefficients of the sail blade, during which the patterns of three-dimensional flow around airflow and the pressure distribution field were obtained. The triangular sail blade is used as the power element of wind turbines. The sail blade modeling was based on the Reynolds-averaged Navier–Stokes equations (RANS) using the ANSYS FLUENT computer program. A flow pattern is obtained, which gives a physical explanation of the nature of the airflow around the sail blade and the pressure distribution field. Comparative analyses of theory and experiment are given. In the range of Reynolds numbers from 0.5 × 104 to 2.5 × 104, the change in the drag force coefficient is from 1.04 to 0.54, and the difference in the lift force coefficient is from 0.52 to 0.33.
- Published
- 2023
- Full Text
- View/download PDF
4. Students' Environmental Competence Formation as a Pedagogical Problem
- Author
-
Ponomarenko, Yelena V., Yessaliev, Aidarbek A., Kenzhebekova, Rabiga I., Moldabek, Kulahmet, Larchekova, Liudmila A., Dairbekov, Serik S., and Asambaeva, Lazzat
- Abstract
Environmentally conscious and preparation of competent professionals' in higher education system in Kazakhstan is a priority. The need for more effective environmental competence formation for students actualizes the problem of development and scientific substantiation of the theoretical model of students' environmental competence, methods of their formation, and diagnostics. To achieve this goal, we used a range of methods that are relevant to the problem--analysis, modeling, experiment and synthesis. The developed model of environmental competence is the main competence of future specialists of any profile and reflects the dialectical relationship of the characteristics and functions of environmental competence. It is shown that an environmentally competent individual is willing and able to act competently in situations that threaten life, safety or nature. Structural analysis of environmental competence model revealed the peculiarities of its formation, as well as to develop knowledge about it. The results allowed developing assessment and diagnosis system of students' environmental competence formation. System's application in the course of the experiment showed that 77% of the participants have the environmental competence formed at a low level, which confirmed the need in the author's methodology implementation. This article describes the stages of the author's methodology and provides methodological recommendations for students' environmental competence formation. It is concluded that students' environmental competence formation must direct the pedagogical efforts not so much on the individual components formation of environmental competence as on functional and structural relationships' formation and development between them.
- Published
- 2016
5. The Pharmaceutical Sector of Kazakhstan's Economy: Trends and Problems
- Author
-
Nurpeisov, Borankul G., Nabiev, Erboz N., Mukashev, Temirbay A., Daribekov, Serik S., Raimbekov, Bagdat Kh, Asanova, Maral K., and Bazarbaeva, Leila M.
- Abstract
This research is devoted to the investigation of the general trends in the development of the pharmaceutical industry in the current conditions of economical socialization. The determination of the economic specificity of the modern operation of the pharmaceutical industry is the purpose of the research. It was found that pharmacy is a profitable sphere of investment in spite of the economic crisis. Furthermore, it was found that national pharmaceutical markets of developing countries contributed significantly to the national economies (since the job of locating pharmaceutical manufacturing facilities is being vacated by developed countries), while the markets of developed countries facilitated the prospering of the economies of their countries (since new ways of making manufacturing cheaper provides for comfortable business). In addition, the correlation of data on export and import of pharmaceutical products gives an idea of the leaders of the pharmaceutical market and the peculiarities of their work. The research also found that the manufacturing of generic drugs was a promising branch of pharmacy. The novelty of this research is determined by the necessity of a comprehensive analysis of rapidly changed trends, which can serve as the basis from relevant economic planning.
- Published
- 2016
6. Management of dyslipidaemia in patients with coronary heart disease: Results from the ESC-EORP EUROASPIRE V survey in 27 countries
- Author
-
De Backer, G., Jankowski, P., Kotseva, K., Mirrakhimov, E., Reiner, Z., Rydén, L., Tokgözoğlu, L., Wood, D., De Bacquer, D., Abreu, A., Aguiar, C., Badariene, J., Bruthans, J., Castro Conde, A., Cifkova, R., Crowley, J., Davletov, K., Bacquer, D. De, De Smedt, D., De Sutter, J., Deckers, J.W., Dilic, M., Dolzhenko, M., Druais, H., Dzerve, V., Erglis, A., Fras, Z., Gaita, D., Gotcheva, N., Grobbee, D.E., Gyberg, V., Hasan Ali, H., Heuschmann, P., Hoes, A.W., Lalic, N., Lehto, S., Lovic, D., Maggioni, A.P., Mancas, S., Marques-Vidal, P., Mellbin, L., Miličić, D., Oganov, R., Pogosova, N., Reiner, Ž., Stagmo, M., Störk, S., Sundvall, J., Tsioufis, K., Vulic, D., Wood, D.A., Jennings, C., Adamska, A., Adamska, S., Tuomilehto, J., Schnell, O., Fiorucci, E., Glemot, M., Larras, F., Missiamenou, V., Maggioni, A., Taylor, C., Ferreira, T., Lemaitre, K., Raman, L., DeSmedt, D., Willems, A.M., De Pauw, M., Vervaet, P., Bollen, J., Dekimpe, E., Mommen, N., Van Genechten, G., Dendale, P., Bouvier, C.A., Chenu, P., Huyberechts, D., Persu, A., Begic, A., Durak Nalbantic, A., Dzubur, A., Hadzibegic, N., Iglica, A., Kapidjic, S., Osmanagic Bico, A., Resic, N., Sabanovic Bajramovic, N., Zvizdic, F., Kovacevic-Preradovic, T., Popovic-Pejicic, S., Djekic, D., Gnjatic, T., Knezevic, T., Kos, Lj, Stanetic, B., Topic, G., Georgiev, Borislav, Terziev, A., Vladimirov, G., Angelov, A., Kanazirev, B., Nikolaeva, S., Tonkova, D., Vetkova, M., Milicic, D., Bosnic, A., Dubravcic, M., Glavina, M., Mance, M., Pavasovic, S., Samardzic, J., Batinic, T., Crljenko, K., Delic-Brkljacic, D., Dula, K., Golubic, K., Klobucar, I., Kordic, K., Kos, N., Nedic, M., Olujic, D., Sedinic, V., Blazevic, T., Pasalic, A., Percic, M., Sikic, J., Cífková, R., Hašplová, K., Šulc, P., Wohlfahrt, P., Mayer, O., Jr., Cvíčela, M., Filipovský, J., Gelžinský, J., Hronová, M., Hasan-Ali, H., Bakery, S., Mosad, E., Hamed, H.B., Ibrahim, A., Elsharef, M.A., Kholef, E.F., Shehata, A., Youssef, M., Elhefny, E., Farid, H., Moustafa, T.M., Sobieh, M.S., Kabil, H., Abdelmordy, A., Kiljander, E., Kiljander, P., Koukkunen, H., Mustonen, J., Cremer, C., Frantz, S., Haupt, A., Hofmann, U., Ludwig, K., Melnyk, H., Noutsias, M., Karmann, W., Prondzinsky, R., Herdeg, C., Hövelborn, T., Daaboul, A., Geisler, T., Keller, T., Sauerbrunn, D., Walz-Ayed, M., Ertl, G., Leyh, R., Ehlert, T., Klocke, B., Krapp, J., Ludwig, T., Käs, J., Starke, C., Ungethüm, K., Wagner, M., Wiedmann, S., Tolis, P., Vogiatzi, G., Sanidas, E., Tsakalis, K., Kanakakis, J., Koutsoukis, A., Vasileiadis, K., Zarifis, J., Karvounis, C., Gibson, I., Houlihan, A., Kelly, C., O'Donnell, M., Bennati, M., Cosmi, F., Mariottoni, B., Morganti, M., Cherubini, A., Di Lenarda, A., Radini, D., Ramani, F., Francese, M.G., Gulizia, M.M., Pericone, D., Aigerim, K., Zholdin, B., Amirov, B., Assembekov, B., Chernokurova, E., Ibragimova, F., Kodasbayev, A., Markova, A., Asanbaev, A., Toktomamatov, U., Tursunbaev, M., Zakirov, U., Abilova, S., Arapova, R., Bektasheva, E., Esenbekova, J., Neronova, K., Baigaziev, K., Baitova, G., Zheenbekov, T., Andrejeva, T., Bajare, I., Kucika, G., Labuce, A., Putane, L., Stabulniece, M., Klavins, E., Sime, I., Gedvilaite, L., Pečiuraite, D., Sileikienė, V., Skiauteryte, E., Solovjova, S., Sidabraite, R., Briedis, K., Ceponiene, I., Jurenas, M., Kersulis, J., Martinkute, G., Vaitiekiene, A., Vasiljevaite, K., Veisaite, R., Plisienė, J., Šiurkaitė, V., Vaičiulis, Ž., Czarnecka, D., Kozieł, P., Podolec, P., Nessler, J., Gomuła, P., Mirek-Bryniarska, E., Bogacki, P., Wiśniewski, A., Pająk, A., Wolfshaut-Wolak, R., Bućko, J., Kamiński, K., Łapińska, M., Paniczko, M., Raczkowski, A., Sawicka, E., Stachurska, Z., Szpakowicz, M., Musiał, W., Dobrzycki, S., Bychowski, J., Kosior, D.A., Krzykwa, A., Setny, M., Rak, A., Gąsior, Z., Haberka, M., Szostak-Janiak, K., Finik, M., Liszka, J., Botelho, A., Cachulo, M., Sousa, J., Pais, A., Durazzo, A., Matos, D., Gouveia, R., Rodrigues, G., Strong, C., Guerreiro, R., Aguiar, J., Cruz, M., Daniel, P., Morais, L., Moreira, R., Rosa, S., Rodrigues, I., Selas, M., Apostu, A., Cosor, O., Gaita, L., Giurgiu, L., Hudrea, C., Maximov, D., Moldovan, B., Mosteoru, S., Pleava, R., Ionescu, M., Parepa, I., Arutyunov, A., Ausheva, A., Isakova, S., Karpova, A., Salbieva, A., Sokolova, O., Vasilevsky, A., Pozdnyakov, Y., Antropova, O., Borisova, L., Osipova, I., Aleksic, M., Crnokrak, B., Djokic, J., Hinic, S., Vukasin, T., Zdravkovic, M., Lalic, N.M., Jotic, A., Lalic, K., Lukic, L., Milicic, T., Macesic, M., Stanarcic Gajovic, J., Stoiljkovic, M., Djordjevic, D., Kostic, S., Tasic, I., Vukovic, A., Jug, B., Juhant, A., Krt, A., Kugonjič, U., Chipayo Gonzales, D., Gómez Barrado, J.J., Kounka, Z., Marcos Gómez, G., Mogollón Jiménez, M.V., Ortiz Cortés, C., Perez Espejo, P., Porras Ramos, Y., Colman, R., Delgado, J., Otero, E., Pérez, A., Fernández-Olmo, M.R., Torres-LLergo, J., Vasco, C., Barreñada, E., Botas, J., Campuzano, R., González, Y., Rodrigo, M., de Pablo, C., Velasco, E., Hernández, S., Lozano, C., González, P., Castro, A., Dalmau, R., Hernández, D., Irazusta, F.J., Vélez, A., Vindel, C., Gómez-Doblas, J.J., García Ruíz, V., Gómez, L., Gómez García, M, Jiménez-Navarro, M., Molina Ramos, A., Marzal, D., Martínez, G., Lavado, R., Vidal, A., Boström-Nilsson, V., Kjellström, B., Shahim, B., Smetana, S., Hansen, O., Stensgaard-Nake, E., Klijn, A.J., Mangus, T.J.P., Peters, R.J.G., Scholte op Reimer, W., Snaterse, M., Aydoğdu, S., Ç Erol, Otürk, S., Tulunay Kaya, C., Ahmetoğlu, Y., Ergene, O., Akdeniz, B., Çırgamış, D., Akkoyun H Kültürsay, S., Kayıkçıoğlu, M., Çatakoğlu, A.B., Çengel, A., Koçak, A.A., Ağırbaşlı, M.A., Açıksarı, G., Çekin, M.E., Kaya, E.B., Koçyiğit, D., Öngen, Z., Özmen, E., Sansoy, V., Kaya, A., Oktay, V., Temizhan, A., Ünal, S., İ Yakut, Kalkan, A.K., Bozkurt, E., Kasapkara, H.A., Faradzh, C., Hrubyak, L., Konoplianyk, L., Kozhuharyova, N., Lobach, L., Nesukai, V., Nudchenko, O., Simagina, T., Yakovenko, L., Azarenko, V., Potabashny, V., Bazylevych, A., Bazylevych, M., Kaminska, K., Panchenko, L., Shershnyova, O., Ovrakh, T., Serik, S., Kolesnik, T., Kosova, H., Hoye P Atkin, A., Fellowes, D., Lindsay, S., Atkinson, C., Kranilla, C., Vinod, M., Beerachee, Y., Bennett, C., Broome, M., Bwalya, A., Caygill, Lindsay, Dinning, L., Gillespie, A., Goodfellow, R., Guy, J., Idress, T., Mills, C., Morgan, C., Oustance, N., Singh, N., Yare, M., Jagoda, J.M., Bowyer, H., Christenssen, V., Groves, A., Jan, A., Riaz, A., Gill, M., Sewell, T.A., Gorog, D., Baker, M., De Sousa, P., Mazenenga, T., Porter, J., Haines, F., Peachey, T., Taaffe, J., Wells, K., Ripley, D.P., Forward, H., McKie, H., Pick, S.L., Thomas, H.E., Batin, P.D., Exley, D., Rank, T., Wright, J., Kardos, A., Sutherland, S.-B., Wren, L., Leeson, P., Barker, D., Moreby, B., Sawyer, J., Stirrup, J., Brunton, M., Brodison, A., Craig, J., Peters, S., Kaprielian, R., Bucaj, A., Mahay, K., Oblak, M., Gale, C., Pye, M., McGill, Y., Redfearn, H., Fearnley, M., De Backer, Guy, Jankowski, Piotr, Kotseva, Kornelia, Mirrakhimov, Erkin, Reiner, Željko, Rydén, Lars, Tokgözoğlu, Lale, Wood, David, and De Bacquer, Dirk
- Published
- 2019
- Full Text
- View/download PDF
7. The association of circulating microRNA-126 with inflammation and insulin resistance in patients with coronary artery disease with type 2 diabetes mellitus
- Author
-
Serik, S., primary, Mavrycheva, N., additional, Riabukha, V., additional, Malko, V., additional, Bondar, T., additional, and Chenchik, T., additional
- Published
- 2023
- Full Text
- View/download PDF
8. Different effects of atorvastatin and rosuvastatin on circulating microRNAs-126 and 146a levels in patients with coronary artery disease with type 2 diabetes mellitus
- Author
-
Serik, S., primary, Riabukha, V., additional, Mavrycheva, N., additional, Malko, V., additional, and Bondar, T., additional
- Published
- 2023
- Full Text
- View/download PDF
9. PATHOPHYSIOLOGY MECHANISMS OF CHRONIC HEART FAILURE IN PATIENTS WITH TYPE 2 DIABETES MELLITUS
- Author
-
Gorb Y., Serik S., Tkachenko O., and Ryabukha V.
- Subjects
type 2 diabetes mellitus, diabetic cardiomyopathy, chronic heart failure, pathophysiological mechanisms, early diagnostics - Abstract
Issues of epidemiology and relationship between chronic heart failure (CHF) and type 2 diabetes mellitus (T2DM), their common pathophysiological mechanisms, gender specifics of the pathogenesis and course of CHF in T2DM are considered. The prevalence of CHF of various phenotypes in patients with T2DM and the main factors affecting the prognosis of the disease were analyzed: arterial hypertension (AH), coronary heart disease (CHD), obesity, chronic kidney disease (CKD), peripheral artery disease. The main pathogenetic mechanisms of diabetic cardiomyopathy (DCM), diabetic cardiac autonomic neuropathy (DCAN), as well as modern biochemical and imaging methods for diagnostics the early stages of CHF in T2DM are highlighted.
- Published
- 2023
- Full Text
- View/download PDF
10. Hypoglycemia and cardiac arrhythmias in diabetes mellitus
- Author
-
Serik, S. A., primary and Strona, V. I., additional
- Published
- 2022
- Full Text
- View/download PDF
11. Expanding the Rapeseed Cultivation Area in the South and South-Eastern Regions of Kazakhstan with the Introduction of its Winter Variety
- Author
-
Galiolla T. Meiirman, Sakysh T. Yerzhanova, Serik S. Abayev, Bakyt A. Ainebekova, Amankeldi T. Kenebayev, and Galym O. Shegebayev
- Subjects
General Agricultural and Biological Sciences ,General Biochemistry, Genetics and Molecular Biology - Published
- 2022
12. Circulating microRNA-126 in patients with ischemic heart disease with type 2 diabetes mellitus and its relationship with glucometabolic disorders
- Author
-
Serik, S. A., primary, Mavrycheva, N. R., additional, and Bondar, T. M., additional
- Published
- 2022
- Full Text
- View/download PDF
13. Monocyte chemoattractant protein-1 serum levels in depending on history of percutaneous coronary intervention in patients with coronary artery disease with type 2 diabetes mellitus
- Author
-
Mavrycheva, N., primary and Serik, S., additional
- Published
- 2022
- Full Text
- View/download PDF
14. Circulating micro-146а and pro-inflammatory cytokines in patients with coronary artery disease with type 2 diabetes mellitus
- Author
-
Serik, S., primary, Riabukha, V., additional, and Malko, V., additional
- Published
- 2022
- Full Text
- View/download PDF
15. Correlation between circulating microRNA and lipid indicesin patients with ischemic heart disease and type 2 diabetes mellitus
- Author
-
Serik, S. A., primary, Serdobinska-Kanivets, E. М., additional, and Bondar, T. М., additional
- Published
- 2022
- Full Text
- View/download PDF
16. Expanding the Rapeseed Cultivation Area in the South and South-Eastern Regions of Kazakhstan with the Introduction of its Winter Variety
- Author
-
Meiirman, Galiolla T., primary, Yerzhanova, Sakysh T., additional, Abayev, Serik S., additional, Ainebekova, Bakyt A., additional, Kenebayev, Amankeldi T., additional, and Shegebayev, Galym O., additional
- Published
- 2022
- Full Text
- View/download PDF
17. Dose-dependent effects of rosuvastatin on circulating microRNAs-27a and 221 levels in patients with coronary artery disease with type 2 diabetes mellitus
- Author
-
Serik, S, primary, Riabukha, V, additional, Serdobinska-Kanivets, E, additional, Bondar, T, additional, and Ovrakh, T, additional
- Published
- 2021
- Full Text
- View/download PDF
18. VEGF-A and circulating miсroRNA- 221 levels in patients with ischemic heart disease with type 2 diabetes mellitus
- Author
-
Ovrakh, T.G., primary, Serik, S., additional, Chenchik, T.A., additional, and Bondar, T.N., additional
- Published
- 2021
- Full Text
- View/download PDF
19. Activity of pro-and anti-inflammatory cytokines in patients with coronary artery disease with type 2 diabetes mellitus.
- Author
-
Serik, S., primary, Riabukha, V.V., additional, Chenchik, T.A., additional, and Horb, Y.H., additional
- Published
- 2021
- Full Text
- View/download PDF
20. Circulating microRNA-126, -146а levels in coronary artery disease and type 2 diabetes mellitus
- Author
-
Serik, S., primary, Serdobiska-Kanivets, E., additional, and Kurinna, O., additional
- Published
- 2021
- Full Text
- View/download PDF
21. Circulating miсroRNAs in patients with ischemic heart disease with type 2 diabetes mellitus
- Author
-
Serik, S. A., Serdobinska-Kanivets, E. M., Bondar, T. M., and GI 'L. T. Malaya Therapy National Institute of the National Academy of Medical Sciences of Ukraine', Kharkiv, № 0117U003027
- Subjects
ишемическая болезнь сердца ,сахарный диабет 2 типа ,микроРНК ,coronary artery disease ,type 2 diabetes mellitus ,miсroRNA ,ішемічна хвороба серця ,цукровий діабет 2 типу ,мікроРНК - Abstract
Мета роботи – вивчити рівні циркулювальних мікроРНК-27а, -221 та їхній зв’язок із глікемією та інсулінорезистентністю у хворих на ішемічну хворобу серця (ІХС) і цукровий діабет 2 типу.Матеріали та методи. У дослідження включили 58 хворих на стабільну ІХС і цукровий діабет 2 типу, 22 особи, які хворі на ІХС без діабету. Група контролю – 19 здорових осіб. МікроРНК-27а і -221 визначали у плазмі крові методом полімеразної ланцюгової реакції в режимі реального часу. Результати наведені у відносних одиницях (в.о.) щодо референсної мікроРНК U6.Результати. У хворих на ІХС і діабет рівні циркулюючих мікроРНК-27а (0,69 [0,32; 1,40] в.о.) і 221 (0,54 [0,33; 0,91] в.о.) були нижчими, ніж у групі контролю (р = 0,024, р = 0,006 відповідно) і у групі ІХС без діабету (р = 0,011, р = 0,001 відповідно). У хворих на ІХС без діабету рівні мікроРНК-27а (1,37 [0,63; 2,86] в.о.) і мікроРНК-221 (1,07 [0,62; 2,70] в.о.) невірогідно вищі, ніж у контрольній групі (0,90 [0,61; 2,62] в.о. і 1,05 [0,53; 1,77] в.о. відповідно, р > 0,05). У хворих на ІХС із діабетом позитивна кореляція між мікроРНК (R = 0,319, р = 0,027) вірогідно слабша, ніж у контрольній групі (R = 0,889, р < 0,001) (р < 0,001) та у хворих на ІХС без діабету (R = 0,772, р < 0,001) (р = 0,020). У пацієнтів із діабетом мікроРНК-27а негативно корелювала з глікозильованим гемоглобіном (R = -0,339, р = 0,030), а мікроРНК-221 – з індексом HOMA-IR (R = -0,362, р = 0,006). За результатами ROC-аналізу, зниження обох мікроРНК вірогідно асоціювалося з наявністю діабету у хворих на ІХС. AUC для мікроРНК-27а становила 0,692 (ДІ: 0,575–0,793, р = 0,009), AUС для мікроРНК-221 – 0,728 (ДІ: 0,617–0,821, р = 0,001).Висновки. У хворих на ІХС і цукровий діабет 2 типу рівні циркулювальних мікроРНК-27а і -221 вірогідно знижувалися порівняно і з контролем, і з хворими на ІХС без діабету. Зниження мікроРНК-27а асоціювалося з гіперглікемією, а мікроРНК-221 – з посиленням інсулінорезистентності. У хворих на ІХС без діабету рівні цих мікроРНК не змінювались., The aim of the study was to investigate circulating miRNAs-27a, -221 levels and their relationship with glycemia and insulin resistance in patients with ischemic heart disease (IHD) with type 2 diabetes mellitus.Materials and methods. The study included 58 patients with stable IHD with type 2 diabetes and 22 patients with IHD without diabetes. The control group consisted of 19 healthy persons. MicroRNAs-27a and -221 were determined in blood plasma by real time polymerase chain reaction. Small nuclear RNA U6 was used as endogenous control.Results. In patients with IHD with diabetes circulating microRNAs27a and -221 levels were lower than in the controls (P = 0.024, P = 0.006, respectively) and in nondiabetic patients with IHD (P = 0.011, P = 0.001, respectively). In nondiabetic patients with IHD microRNAs-27a and 221 levels were nonsignificantly higher than in the controls (P > 0.05, for both). In diabetic patients with IHD the positive correlation between microRNAs (R = 0.319, P = 0.027) was significantly weaker than in the controls (R = 0.889, P < 0.001) (P < 0.001) and in nondiabetic patients with IHD (R = 0.772, P < 0.001) (P = 0.020). In patients with IHD with diabetes microRNA-27a negatively correlated with glycosylated hemoglobin (R = -0.339, P = 0.030), and microRNA-221 negatively correlated with the HOMA-IR (R = -0.362, P = 0.006). According to the ROC-analysis the decrease of both miRNAs levels was significantly associated with the presence of diabetes in patients with IHD. AUC for microRNA-27a was 0.692 (CI: 0.575–0.793, P = 0.009), AUC for microRNA-221 was 0.728 (CI: 0.617–0.821, P = 0.001).Conclusions. In patients with IHD with type 2 diabetes mellitus circulating microRNAs-27a and -221 levels significantly decreased in comparison with both control and patients with IHD without diabetes. The decrease of microRNA-27a was associated with hyperglycemia, and the decrease of microRNA-221 was associated with the increase of insulin resistance. In patients with IHD without diabetes these microRNAs levels did not change., Цель работы – изучить уровни циркулирующих микроРНК-27а, -221 и их связь с гликемией и инсулинорезистентностью у больных ишемической болезнью сердца (ИБС) с сахарным диабетом 2 типа.Материалы и методы. В исследование включены 58 больных стабильной ИБС с сахарным диабетом 2 типа, 22 больных ИБС без диабета. Группу контроля составили 19 здоровых лиц. МикроРНК-27а и -221 определяли в плазме крови методом полимеразной цепной реакции в режиме реального времени. Результаты представлены в относительных единицах (о.е.) по отношению к референсной микроРНК U6.Результаты. У больных ИБС с диабетом уровни циркулирующих микроРНК-27а (0,69 [0,32; 1,40] о.е.) и -221 (0,54 [0,33; 0,91] о.е.) были ниже, чем в группе контроля (р = 0,024, р = 0,006 соответственно) и в группе ИБС без диабета (р = 0,011, р = 0,001 соответственно). У больных ИБС без диабета уровни микроРНК-27а (1,37 [0,63; 2,86] о.е.) и микроРНК-221 (1,07 [0,62; 2,70] о.е.) оказались незначимо выше, чем в контрольной группе (0,90 [0,61; 2,62] о.е. и 1,05 [0,53; 1,77] о.е. соответственно, р > 0,05). У больных ИБС с диабетом позитивная корреляция между микроРНК (R = 0,319, р = 0,027) достоверно слабее, чем в контрольной группе (R = 0,889, р < 0,001) (р < 0,001) и у больных ИБС без диабета (R = 0,772, р < 0,001) (р = 0,020). У пациентов с диабетом микроРНК-27а негативно коррелировала с гликозилированным гемоглобином (R = -0,339, р = 0,030), а микроРНК-221 – с индексом HOMA-IR (R = -0,362, р = 0,006). По результатам ROC-анализа, снижение обеих микроРНК достоверно ассоциировалось с наличием диабета у больных ИБС. AUC для микроРНК-27а составила 0,692 (ДИ: 0,575–0,793, р = 0,009), AUС для микроРНК-221 равна 0,728 (ДИ: 0,617–0,821, р = 0,001).Выводы. У больных ИБС с сахарным диабетом 2 типа уровни циркулирующих микроРНК-27а и -221 достоверно снижались по сравнению и с контролем, и с больными ИБС без диабета. Снижение микроРНК-27а ассоциировалось с гипергликемией, а микроРНК-221 – с нарастанием инсулинорезистентности. У больных ИБС без диабета уровни этих микроРНК не изменялись.
- Published
- 2020
22. Rivaroxaban for thromboprophylaxis after hospitalization for medical illness
- Author
-
Spyropoulos, A, Ageno, W, Albers, G, Elliott, C, Halperin, J, Hiatt, W, Maynard, G, Steg, P, Weitz, J, Suh, E, Spiro, T, Barnathan, E, Raskob, G, Douketis, J, Turpie, A, Schulman, S, Kearon, C, Linkins, L, Schellong, S, Bauer, K, Geerts, W, Roberts, R, Casais, P, Gallus, A, Karrasch, J, Eichinger-Hasenauer, S, Krivenchuk, V, Hadzovic-Dzuvo, A, Trbojevic, S, Lopes, R, Mincheva, V, Carrier, M, Dennis, R, Tudoric, N, Spinar, J, Nielsen, H, Marandi, T, Shaburishvili, T, Beyer-Westendorf, J, Vardas, P, Boda, Z, Brenner, B, Piovella, F, Krievins, D, Petrauskiene, B, Dejanova-Ilijevska, V, Virgen Carrillo, L, Middeldorp, S, Castillo Leon, R, Torbicki, A, Saraiva de Sousa, M, Dorobantu, M, Militaru, C, Yavelov, I, Vuckovic, B, Reuter, H, Basson, M, Monreal, M, Kucukoglu, S, Parkhomenko, A, Alikhan, R, Rosenberg, D, Yusen, R, Khorana, A, Tapson, V, Pollack, C, Hazelrigg, M, Jure, H, Alvarisqueta, A, Cartasegna, L, Hominal, M, Cursack, G, Alzogaray, M, Maillo, M, Parody, M, Caccavo, A, Dran, R, Muntaner, J, Casas, M, Schmidberg, J, Sarjanovich, R, Gabito, A, Garrido, M, Amuchastegui, M, Fernandez, A, Loureyro, J, Giumelli, C, Heazlewood, V, Colquhoun, D, White, H, Sabet, A, Bowler, S, Carroll, P, Khalafallah, A, Baker, R, Hedger, S, Simpson, F, Jackson, D, Chong, B, Siostrzonek, P, Gary, T, Hoppe, U, Dosta, N, Prystrom, A, Gorokhovsky, S, Yanushko, V, Skrahin, A, Kulik, A, Maslianski, B, Yakubtsevich, R, Timkin, I, Moguchaya, O, Tanaskovic, N, Miljkovic, S, Stojkovic, S, Kovacevic-Preradovic, T, Jovic, D, Basagic, E, Radjen, M, Mutapcic, M, Rizvanovic-Vojic, E, Galic, K, Terzic, I, Pojskic, B, Stevanovic, D, Cehajic, M, Rech, R, Annichino-Bizzacchi, J, Stelmach, R, Blanco, D, Castro, I, Backes, L, Saraiva, J, Ramacciotti, E, de Barros e Silva, P, Reis, G, Moreira Vieira, E, Leaes, P, Zimmermann, S, Van Bellen, B, Precoma, D, Luiz Silvestrini, T, Hernandes, M, Kyoleyan, M, Kalinova, T, Tiholov, R, Petrov, I, Mihov, A, Chompalova, B, Velikov, C, Pencheva, G, Atanasov, P, Raev, D, Kinova, E, Peltegov, V, Marchev, S, Siulemezova, S, Ayryanova, I, Grigorov, M, Naydenova, I, Koteva, N, Dimov, B, Runev, N, Getov, D, Metev, H, Donchev, K, Taseva, M, Hadzhieva, A, Benov, H, Stoyanov, M, Tisheva-Gospodinova, S, Mihaylova, N, Abadzhiev, S, Atzev, B, Georgiev, R, Mollov, M, Stoikov, A, Mazhdrakov, G, Karastanev, K, Dube, F, Roth, S, Mansour, S, Wu, C, Dolan, S, Pesant, Y, Pietrangelo, M, Dresser, G, Kahn, S, Kruisselbrink, R, Cadena Bonfanti, A, Botero, R, Quintero Ossa, A, Poveda, C, Cedano, J, Gomez Isaza, L, Villaquiran Torres, C, Gomez Mesa, J, Vargas Alonso, R, Espinosa, D, Rodriguez, J, Sanchez, G, Accini Mendoza, J, Gomez Florez, C, Cuervo Millan, F, Pesek, K, Horvat, D, Fuckar, K, Ruzic, A, Ostricki, B, Knezevic, A, Breitenfeld, T, Laganovic, M, Samodol, A, Sikic, J, Starcevic, B, Babic, Z, Samarzija, M, Milas, K, Votocek, S, Kvapil, M, Kolman, P, Bindas, P, Simon, V, Adamek, T, Svobodova, J, Gergely, L, Lastuvka, J, Macel, I, Navratil, K, Gregor, P, Lacnak, B, Janousek, J, Kellnerova, I, Hulinsky, V, Matusek, Z, Prucek, L, Dunaj, M, Pirchala, M, Vencour, D, Pavolko, M, Gorican, K, Fiksa, J, Tuxen, C, Meyer, C, Suppli Ulrik, C, Uuetoa, T, Otarishvili, N, Khintibidze, I, Emukhvari, N, Kipiani, Z, Gochitashvili, D, Mamatsashvili, M, Megreladze, I, Paposhvili, K, Agladze, R, Eradze, Z, Chelidze, K, Lominadze, S, Chukhrukidze, A, Chumburidze, V, Metreveli, S, Danelia, V, Orjonikidze, S, Kobulia, B, Nikolaishvili, G, Gvenetadze, R, Melia, A, Tsinamdzgvrishvili, B, Sekhniashvili, M, Sikharulidze, I, Meuser, M, Licka, M, Rauch-Kroehnert, U, Graf, K, Brachmann, J, Akin, I, Toumbis, M, Vassilikos, V, Konstantinides, S, Steiropoulos, P, Gogos, C, Andrikopoulos, G, Parthenakis, F, Karydi, P, Tsivgoulis, G, Mertzanos, G, Olympios, C, Karapanayiotides, T, Paraskevopoulou, E, Kifnidis, K, Hahalis, G, Skoutelis, A, Vadikolias, K, Nyirati, G, Nagy, L, Matoltsy, A, Komoly, S, Lippai, J, Kiss, K, Toth, K, Pozsegovits, K, Kiraly, C, Bereczki, D, Zolyomi, S, Szakal, I, Pall, D, Futo, L, Forster, T, Lovasz, O, Papp, A, Kiraly, Z, Pozsonyi, Z, Hajko, E, Kristof, P, Lakatos, F, Ples, Z, Kirschner, R, Lupkovics, G, Timar, G, Pinter, I, Kristof, T, Kis, E, Kovacs, A, Jakab, G, Palinkas, A, Muller, G, Turi, T, Horvath, C, Kondakor, I, Csanyi, A, Frankfurter, Z, Gurzo, M, Gafter-Gvili, A, Kuchuk, M, Azzam, Z, Elis, A, Halabi, M, Hussein, O, Blum, A, Tsoran-Rosenthal, I, Lishner, M, Hochberg-Klein, S, Caraco, Y, Atar, S, Elias, N, Gavish, D, Butnaru, A, Cosmi, F, Garbelotto, R, Giorgi Pierfranceschi, M, Simioni, L, Gronda, E, Pesci, A, D'Angelo, A, Fedele, F, Ghirarduzzi, A, Piovaccari, G, Lembo, G, Ria, L, Monaco, G, Brunelli, C, Tosetto, A, Capucci, A, Zanatta, N, Pistolesi, M, Mazzi, V, Testa, S, Scherillo, M, Di Biase, M, Antonicelli, R, Lodigiani, C, Nassiacos, D, Viksne, I, Lapkovska, Z, Rancane, G, Sime, I, Pontaga, N, Eglite, R, Puzule, S, Smolova, R, Butkiene, Z, Bagdonas, A, Raugaliene, R, Norkiene, S, Norviliene, R, Basijokiene, V, Stonkus, S, Griskeviciene, V, Miskiniene, A, Norvaisiene, R, Skripkauskiene, I, Jovkovska-Kaeva, B, Kochovska-Kamchevska, N, Antovski, A, Nechevska, L, Celeska, V, Ilievska-Poposka, B, Kostojchinoska, M, Donchovska, S, Kedev, S, Kuzmanovski, I, Bushletikj, O, Stojchev, S, Bakrachevski, N, Kuzmanovska, B, Angusheva, T, Llamas Esperon, G, Valdez Lopez, H, Medina Pech, C, Cortes Hernandez, M, Gans, S, Smulders, S, Swart, H, Boersma, W, Goosens, M, Hovens, M, Semplonius, G, Sohne, M, Lema Osores, J, Salas Perez, M, Rodriguez, A, Rios Oliva, C, Cotrina, R, Berrospi Argandona, P, Toce Yanez, L, Chavez Ayala, C, Mirek-Bryniarska, E, Goch, A, Skucha, W, Skorski, M, Miekus, P, Szyszka, A, Piotrowski, G, Gniot, J, Czerski, T, Debich, P, Zaluska, R, Bebenek, W, Wozakowska-Kaplon, B, Sciborski, R, Ilkowski, J, Wojnowski, P, Uscinska, E, Gaciong, Z, Bonek, R, Sobkowicz, B, Berkowski, P, Bejgier, K, Polonski, L, Kosior, D, Lata, S, Kolodziej, P, Gessek, J, Kachel, T, Talalaj, M, Musial, J, Lewczuk, J, Krysiak, W, Kucharski, L, Wysokinski, A, Minc, P, Martinez, J, Gregorio, T, Almeida, F, Monteiro, P, Stanciulescu, G, Mercea, C, Iosipescu, L, Ciobotaru, V, Crisu, D, Burca, M, Tudoran, M, Savu, A, Negrean, V, Cojocaru, C, Minescu, B, Popa, V, Blajan, D, Nastase-Melicovici, D, Fruntelata, A, Barbulescu, S, Lukinyh, L, Akhunova, S, Vishneva, E, Semenova, I, Nikolaev, K, Shaydyuk, O, Nilk, R, Shalnev, V, Apartsin, K, Goloshchekin, B, Shpagina, L, Khlevchuk, T, Arkhipov, M, Malygin, A, Shvarts, Y, Khaisheva, L, Popov, D, Kobalava, Z, Lipchenko, A, Shapovalova, Y, Zrazhevsky, K, Greshnova, I, Maslova, N, Karabenenko, A, Shogenov, Z, Budankova, E, Barbarash, O, Uspenskiy, Y, Kosmacheva, E, Berns, S, Kostenko, V, Zateyshchikov, D, Vishnevsky, A, Boldueva, S, Podzolkov, V, Sergeeva, E, Grinshtein, Y, Khrustalev, O, Bugrova, O, Repin, A, Andreev, D, Petrovic, P, Boskovic Matic, T, Apostolovic, S, Lazic, Z, Stankovic, D, Stankovic, A, Mitov, V, Sofronic, D, Kopitovic, I, Zdravkovic, V, Joksimovic, Z, Lazovic, N, Petrovic-Stanojevic, N, Ilic, A, Vujadinovic, O, Pencic-Popovic, B, Andjelkovic, N, Sekularac, N, Hinic, S, Radjen, G, Zivkovic, A, Putnikovic, B, Ivanov, I, Babic, R, Van Zyl, L, Hobson, B, Engelbrecht, J, Mitha, I, Siebert, H, Jacobson, B, Breedt, J, Prozesky, H, Ntsekhe, M, Bayat, J, Ellis, G, Tarr, G, Adler, D, Van Dyk, C, Ismail, S, Spargo, C, Abdool-Gaffar, M, Saaiman, J, Venter, K, Lorente Aroca, M, Fernandez Portales, F, Pedrajas Navas, J, Rodriguez Botaro, A, Santa Cruz Siminiani, A, Lopez Reyes, R, Bisbe i Company, J, Piedecausa Selfa, M, Velasco Garrido, J, Sobrino-Martinez, J, Munoz Delgado, G, Sala Llinas, E, Blanco Coronado, J, Almenar Bonet, L, Vida Gutierrez, M, Sanchez Lora, F, Sanchez Martinez, R, Calderon, E, Villalta Blanch, J, De la Hera Galarza, J, Bustamante Ruiz, A, Garcia-Fuster, M, Ripoll Vera, T, Alvarez-Sala Walter, L, Todoli Parra, J, Diaz Fernandez, J, Bosa Ojeda, F, Pellicer-Ciscar, C, Jara Palomares, L, Quiles Granado, J, Trigo Bautista, A, Ruiz Bustillo, S, Ordi Ros, J, Tolosa-Vilella, C, Marin Ortuno, F, Garcia Sanchez, F, Barba Martin, R, Segovia Cubero, J, Cuervas-Mons Martinez, V, Galan Montejano, M, Lopez Meseguer, M, Sener Comert, S, Koksal, N, Tertemiz, K, Ernam, D, Dursun, A, Yildiz, O, Rudenko, L, Abrahamovych, O, Goloborodko, A, Holovchenko, N, Kulyk, A, Yagensky, A, Batushkin, V, Zolotaikina, V, Kozyolkin, O, Faynyk, A, Maslovskyy, V, Petrovskyy, R, Koshlia, V, Chopey, I, Burmak, I, Malynovsky, Y, Voronkov, L, Karpenko, O, Dziublyk, O, Godlevska, O, Borovyk, V, Bezrodna, L, Serik, S, Ovsyannikova, N, Vynnychenko, L, Kopytsya, M, Rudkovskiy, V, Grishyna, O, Vyshnyvetskyy, I, Prystupa, L, Tseluyko, V, Perepeliuk, M, Koval, O, Sychov, O, Church, A, Goudie, A, Elliott, M, Ferguson, C, Welker, J, Kao, C, Bhagwat, R, Serota, H, Bozorgchami, H, Nambiar, R, Spilseth, S, Bhagwath, G, Syed, F, Morrow, L, Updegrove, J, Bercz, P, Kambo, V, Henderson, D, Wright, P, Dang, N, Nadar, V, Jaffrani, N, El-Shahawy, M, Grossman, C, Pearle, J, Weinstein, D, Galanis, T, Gazmuri, R, Kastelic, R, Martinez, R, Laman, D, Macchiavelli, A, Kmetzo, J, Thurm, C, Kayembe, T, Chandrashekhar, Y, Bassetti, D, Jaoude, P, Williams, H, Dewhurst, R, Naqvi, S, Burr, J, Rodriguez-Cintron, W, Jeanfreau, R, Kosinski, E, Ndukwu, I, Sotolongo, C, Daboul, N, Wilmer, C, Simon, P, Tak, T, Rees, C, Gupta, N, Lerner, R, Graffagnino, C, Reed, R, Alford, C, Mody, F, Wellmon, B, Hamroff, G, Rajan, R, Kaatz, S, Spyropoulos A. C., Ageno W., Albers G. W., Elliott C. G., Halperin J. L., Hiatt W. R., Maynard G. A., Steg P. G., Weitz J. I., Suh E., Spiro T. E., Barnathan E. S., Raskob G. E., Douketis J., Turpie A. G., Schulman S., Kearon C., Linkins L. A., Schellong S., Bauer K., Geerts W., Roberts R., Casais P., Gallus A., Karrasch J., Eichinger-Hasenauer S., Krivenchuk V., Hadzovic-Dzuvo A., Trbojevic S., Lopes R., Mincheva V., Carrier M., Dennis R., Tudoric N., Spinar J., Nielsen H., Marandi T., Shaburishvili T., Beyer-Westendorf J., Vardas P., Boda Z., Brenner B., Piovella F., Krievins D., Petrauskiene B., Dejanova-Ilijevska V., Virgen Carrillo L. R., Middeldorp S., Castillo Leon R. P., Torbicki A., Saraiva de Sousa M., Dorobantu M., Militaru C., Yavelov I., Vuckovic B., Reuter H., Basson M., Monreal M., Kucukoglu S., Parkhomenko A., Alikhan R., Rosenberg D., Yusen R., Khorana A., Tapson V., Pollack C., Hazelrigg M., Jure H., Alvarisqueta A., Cartasegna L., Hominal M., Cursack G., Alzogaray M., Maillo M., Parody M., Caccavo A., Dran R. D., Muntaner J. A., Casas M., Schmidberg J., Sarjanovich R., Gabito A., Garrido M., Amuchastegui M., Fernandez A., Loureyro J., Giumelli C., Heazlewood V., Colquhoun D., White H., Sabet A., Bowler S., Carroll P., Khalafallah A., Baker R., Hedger S., Simpson F. G., Jackson D., Chong B., Siostrzonek P., Gary T., Hoppe U., Dosta N., Prystrom A., Gorokhovsky S., Yanushko V., Skrahin A., Kulik A., Maslianski B., Yakubtsevich R., Timkin I., Moguchaya O., Tanaskovic N., Miljkovic S., Stojkovic S., Kovacevic-Preradovic T., Jovic D., Basagic E., Radjen M., Mutapcic M., Rizvanovic-Vojic E., Galic K., Terzic I., Pojskic B., Stevanovic D., Cehajic M., Rech R., Annichino-Bizzacchi J., Stelmach R., Blanco D., Castro I., Backes L. M., Saraiva J. F., Ramacciotti E., de Barros e Silva P. G. M., Reis G., Moreira Vieira E., Leaes P., Zimmermann S., Van Bellen B., Precoma D., Luiz Silvestrini T., Hernandes M. E., Kyoleyan M., Kalinova T., Tiholov R., Petrov I., Mihov A., Chompalova B., Velikov C., Pencheva G., Atanasov P., Raev D., Kinova E., Peltegov V., Marchev S., Siulemezova S., Ayryanova I. D., Grigorov M., Naydenova I., Koteva N., Dimov B., Runev N., Getov D., Metev H., Donchev K., Taseva M., Hadzhieva A., Benov H., Stoyanov M., Tisheva-Gospodinova S., Mihaylova N., Abadzhiev S., Atzev B., Georgiev R., Mollov M., Stoikov A., Mazhdrakov G., Karastanev K., Dube F., Roth S., Mansour S., Wu C., Dolan S., Pesant Y., Pietrangelo M., Dresser G., Kahn S., Kruisselbrink R., Cadena Bonfanti A., Botero R., Quintero Ossa A., Poveda C. M., Cedano J., Gomez Isaza L., Villaquiran Torres C., Gomez Mesa J., Vargas Alonso R., Espinosa D., Rodriguez J. M., Sanchez G., Accini Mendoza J. L., Gomez Florez C. C., Cuervo Millan F., Pesek K., Horvat D., Fuckar K., Ruzic A., Ostricki B., Knezevic A., Breitenfeld T., Laganovic M., Samodol A., Sikic J., Starcevic B., Babic Z., Samarzija M., Milas K., Votocek S., Kvapil M., Kolman P., Bindas P., Simon V., Adamek T., Svobodova J., Gergely L., Lastuvka J., Macel I., Navratil K., Gregor P., Lacnak B., Janousek J., Kellnerova I., Hulinsky V., Matusek Z., Prucek L., Dunaj M., Pirchala M., Vencour D., Pavolko M., Gorican K., Fiksa J., Tuxen C., Meyer C., Suppli Ulrik C., Uuetoa T., Otarishvili N., Khintibidze I., Emukhvari N., Kipiani Z., Gochitashvili D., Mamatsashvili M., Megreladze I., Paposhvili K., Agladze R., Eradze Z., Chelidze K., Lominadze S., Chukhrukidze A., Chumburidze V., Metreveli S., Danelia V., Orjonikidze S., Kobulia B., Nikolaishvili G., Gvenetadze R., Melia A., Tsinamdzgvrishvili B., Sekhniashvili M., Sikharulidze I., Meuser M., Licka M., Rauch-Kroehnert U., Graf K., Brachmann J., Akin I., Toumbis M., Vassilikos V., Konstantinides S., Steiropoulos P., Gogos C., Andrikopoulos G., Parthenakis F., Karydi P., Tsivgoulis G., Mertzanos G., Olympios C., Karapanayiotides T., Paraskevopoulou E., Kifnidis K., Hahalis G., Skoutelis A., Vadikolias K., Nyirati G., Nagy L., Matoltsy A., Komoly S., Lippai J., Kiss K., Toth K., Pozsegovits K., Kiraly C., Bereczki D., Zolyomi S., Szakal I., Pall D., Futo L., Forster T., Lovasz O., Papp A., Kiraly Z., Pozsonyi Z., Hajko E., Kristof P., Lakatos F., Ples Z., Kirschner R., Lupkovics G., Timar G., Pinter I., Kristof T., Kis E., Kovacs A., Jakab G., Palinkas A., Muller G., Turi T., Horvath C., Kondakor I., Csanyi A., Frankfurter Z., Gurzo M., Gafter-Gvili A., Kuchuk M., Azzam Z., Elis A., Halabi M., Hussein O., Blum A., Tsoran-Rosenthal I., Lishner M., Hochberg-Klein S., Caraco Y., Atar S., Elias N., Gavish D., Butnaru A., Cosmi F., Garbelotto R., Giorgi Pierfranceschi M., Simioni L., Gronda E., Pesci A., D'Angelo A., Fedele F., Ghirarduzzi A., Piovaccari G., Lembo G., Ria L., Monaco G. L., Brunelli C., Tosetto A., Capucci A., Zanatta N., Pistolesi M., Mazzi V., Testa S., Scherillo M., Di Biase M., Antonicelli R., Lodigiani C., Nassiacos D., Viksne I., Lapkovska Z., Rancane G., Sime I., Pontaga N., Eglite R., Puzule S., Smolova R., Butkiene Z., Bagdonas A., Raugaliene R., Norkiene S., Norviliene R., Basijokiene V., Stonkus S., Griskeviciene V., Miskiniene A., Norvaisiene R., Skripkauskiene I., Jovkovska-Kaeva B., Kochovska-Kamchevska N., Antovski A., Nechevska L., Celeska V., Ilievska-Poposka B., Kostojchinoska M., Donchovska S., Kedev S., Kuzmanovski I., Bushletikj O., Stojchev S., Bakrachevski N., Kuzmanovska B., Angusheva T., Llamas Esperon G., Valdez Lopez H., Medina Pech C., Cortes Hernandez M., Virgen Carrillo L., Gans S., Smulders S., Swart H., Boersma W., Goosens M., Hovens M., Semplonius G., Sohne M., Lema Osores J., Salas Perez M. D., Rodriguez A., Rios Oliva C., Cotrina R., Berrospi Argandona P., Toce Yanez L., Chavez Ayala C., Mirek-Bryniarska E., Goch A., Skucha W., Skorski M., Miekus P., Szyszka A., Piotrowski G., Gniot J., Czerski T., Debich P., Zaluska R., Bebenek W., Wozakowska-Kaplon B., Sciborski R., Ilkowski J., Wojnowski P., Uscinska E., Gaciong Z., Bonek R., Sobkowicz B., Berkowski P., Bejgier K., Polonski L., Kosior D., Lata S., Kolodziej P., Gessek J., Kachel T., Talalaj M., Musial J., Lewczuk J., Krysiak W., Kucharski L., Wysokinski A., Minc P., Martinez J., Gregorio T., Almeida F., Monteiro P., Stanciulescu G., Mercea C. D., Iosipescu L. C., Ciobotaru V., Crisu D., Burca M., Tudoran M., Savu A., Negrean V., Cojocaru C., Minescu B., Popa V., Blajan D., Nastase-Melicovici D., Fruntelata A., Barbulescu S., Lukinyh L., Akhunova S., Vishneva E., Semenova I., Nikolaev K. Y., Shaydyuk O., Nilk R., Shalnev V., Apartsin K., Goloshchekin B. M., Shpagina L., Khlevchuk T., Arkhipov M., Malygin A., Shvarts Y., Khaisheva L., Popov D., Kobalava Z., Lipchenko A., Shapovalova Y., Zrazhevsky K., Greshnova I., Maslova N., Karabenenko A., Shogenov Z., Budankova E., Barbarash O., Uspenskiy Y., Kosmacheva E., Berns S., Kostenko V., Zateyshchikov D., Vishnevsky A., Boldueva S., Podzolkov V., Sergeeva E., Grinshtein Y., Khrustalev O., Bugrova O., Repin A., Andreev D., Petrovic P., Boskovic Matic T., Apostolovic S., Lazic Z., Stankovic D., Stankovic A., Mitov V., Sofronic D., Kopitovic I., Zdravkovic V., Joksimovic Z., Lazovic N., Petrovic-Stanojevic N., Ilic A., Vujadinovic O., Pencic-Popovic B., Andjelkovic N., Sekularac N., Hinic S., Radjen G., Zivkovic A., Putnikovic B., Ivanov I., Babic R., Van Zyl L., Hobson B., Engelbrecht J., Mitha I., Siebert H., Jacobson B., Breedt J., Prozesky H., Ntsekhe M., Bayat J., Ellis G., Tarr G., Adler D., Van Dyk C., Ismail S. M., Spargo C. E., Abdool-Gaffar M., Saaiman J., Venter K., Lorente Aroca M. L., Fernandez Portales F., Pedrajas Navas J., Rodriguez Botaro A., Santa Cruz Siminiani A., Lopez Reyes R., Bisbe i Company J., Piedecausa Selfa M., Velasco Garrido J., Sobrino-Martinez J., Munoz Delgado G., Sala Llinas E., Blanco Coronado J., Almenar Bonet L., Vida Gutierrez M., Sanchez Lora F., Sanchez Martinez R., Calderon E. J., Villalta Blanch J., De la Hera Galarza J. M., Bustamante Ruiz A., Garcia-Fuster M. J., Ripoll Vera T., Alvarez-Sala Walter L., Todoli Parra J. A., Diaz Fernandez J., Bosa Ojeda F., Pellicer-Ciscar C., Jara Palomares L., Quiles Granado J., Trigo Bautista A., Ruiz Bustillo S., Ordi Ros J., Tolosa-Vilella C., Marin Ortuno F., Garcia Sanchez F., Barba Martin R., Segovia Cubero J., Cuervas-Mons Martinez V., Galan Montejano M., Lopez Meseguer M., Sener Comert S., Koksal N., Tertemiz K., Ernam D., Dursun A. B., Yildiz O., Rudenko L., Abrahamovych O., Goloborodko A., Holovchenko N., Kulyk A., Yagensky A., Batushkin V., Zolotaikina V., Kozyolkin O., Faynyk A., Maslovskyy V., Petrovskyy R., Koshlia V., Chopey I., Burmak I., Malynovsky Y., Voronkov L., Karpenko O., Dziublyk O., Godlevska O., Borovyk V., Bezrodna L., Serik S., Ovsyannikova N., Vynnychenko L., Kopytsya M., Rudkovskiy V., Grishyna O., Vyshnyvetskyy I., Prystupa L., Tseluyko V., Perepeliuk M., Koval O., Sychov O., Church A., Goudie A., Elliott M., Ferguson C., Welker J., Kao C. K., Bhagwat R., Serota H., Bozorgchami H., Nambiar R., Spilseth S., Bhagwath G., Syed F., Morrow L., Updegrove J., Bercz P., Kambo V., Henderson D., Wright P., Dang N., Nadar V., Jaffrani N., El-Shahawy M., Grossman C. H., Pearle J., Weinstein D., Galanis T. P., Gazmuri R., Kastelic R., Martinez R., Laman D., Macchiavelli A., Kmetzo J., Thurm C., Kayembe T., Chandrashekhar Y., Bassetti D., Jaoude P., Williams H., Dewhurst R., Naqvi S., Burr J., Rodriguez-Cintron W., Jeanfreau R., Kosinski E., Ndukwu I. M., Sotolongo C., Daboul N., Wilmer C., Simon P., Tak T., Rees C., Gupta N., Lerner R., Graffagnino C., Reed R. M., Alford C. M., Mody F., Wellmon B., Hamroff G., Rajan R., Kaatz S., Spyropoulos, A, Ageno, W, Albers, G, Elliott, C, Halperin, J, Hiatt, W, Maynard, G, Steg, P, Weitz, J, Suh, E, Spiro, T, Barnathan, E, Raskob, G, Douketis, J, Turpie, A, Schulman, S, Kearon, C, Linkins, L, Schellong, S, Bauer, K, Geerts, W, Roberts, R, Casais, P, Gallus, A, Karrasch, J, Eichinger-Hasenauer, S, Krivenchuk, V, Hadzovic-Dzuvo, A, Trbojevic, S, Lopes, R, Mincheva, V, Carrier, M, Dennis, R, Tudoric, N, Spinar, J, Nielsen, H, Marandi, T, Shaburishvili, T, Beyer-Westendorf, J, Vardas, P, Boda, Z, Brenner, B, Piovella, F, Krievins, D, Petrauskiene, B, Dejanova-Ilijevska, V, Virgen Carrillo, L, Middeldorp, S, Castillo Leon, R, Torbicki, A, Saraiva de Sousa, M, Dorobantu, M, Militaru, C, Yavelov, I, Vuckovic, B, Reuter, H, Basson, M, Monreal, M, Kucukoglu, S, Parkhomenko, A, Alikhan, R, Rosenberg, D, Yusen, R, Khorana, A, Tapson, V, Pollack, C, Hazelrigg, M, Jure, H, Alvarisqueta, A, Cartasegna, L, Hominal, M, Cursack, G, Alzogaray, M, Maillo, M, Parody, M, Caccavo, A, Dran, R, Muntaner, J, Casas, M, Schmidberg, J, Sarjanovich, R, Gabito, A, Garrido, M, Amuchastegui, M, Fernandez, A, Loureyro, J, Giumelli, C, Heazlewood, V, Colquhoun, D, White, H, Sabet, A, Bowler, S, Carroll, P, Khalafallah, A, Baker, R, Hedger, S, Simpson, F, Jackson, D, Chong, B, Siostrzonek, P, Gary, T, Hoppe, U, Dosta, N, Prystrom, A, Gorokhovsky, S, Yanushko, V, Skrahin, A, Kulik, A, Maslianski, B, Yakubtsevich, R, Timkin, I, Moguchaya, O, Tanaskovic, N, Miljkovic, S, Stojkovic, S, Kovacevic-Preradovic, T, Jovic, D, Basagic, E, Radjen, M, Mutapcic, M, Rizvanovic-Vojic, E, Galic, K, Terzic, I, Pojskic, B, Stevanovic, D, Cehajic, M, Rech, R, Annichino-Bizzacchi, J, Stelmach, R, Blanco, D, Castro, I, Backes, L, Saraiva, J, Ramacciotti, E, de Barros e Silva, P, Reis, G, Moreira Vieira, E, Leaes, P, Zimmermann, S, Van Bellen, B, Precoma, D, Luiz Silvestrini, T, Hernandes, M, Kyoleyan, M, Kalinova, T, Tiholov, R, Petrov, I, Mihov, A, Chompalova, B, Velikov, C, Pencheva, G, Atanasov, P, Raev, D, Kinova, E, Peltegov, V, Marchev, S, Siulemezova, S, Ayryanova, I, Grigorov, M, Naydenova, I, Koteva, N, Dimov, B, Runev, N, Getov, D, Metev, H, Donchev, K, Taseva, M, Hadzhieva, A, Benov, H, Stoyanov, M, Tisheva-Gospodinova, S, Mihaylova, N, Abadzhiev, S, Atzev, B, Georgiev, R, Mollov, M, Stoikov, A, Mazhdrakov, G, Karastanev, K, Dube, F, Roth, S, Mansour, S, Wu, C, Dolan, S, Pesant, Y, Pietrangelo, M, Dresser, G, Kahn, S, Kruisselbrink, R, Cadena Bonfanti, A, Botero, R, Quintero Ossa, A, Poveda, C, Cedano, J, Gomez Isaza, L, Villaquiran Torres, C, Gomez Mesa, J, Vargas Alonso, R, Espinosa, D, Rodriguez, J, Sanchez, G, Accini Mendoza, J, Gomez Florez, C, Cuervo Millan, F, Pesek, K, Horvat, D, Fuckar, K, Ruzic, A, Ostricki, B, Knezevic, A, Breitenfeld, T, Laganovic, M, Samodol, A, Sikic, J, Starcevic, B, Babic, Z, Samarzija, M, Milas, K, Votocek, S, Kvapil, M, Kolman, P, Bindas, P, Simon, V, Adamek, T, Svobodova, J, Gergely, L, Lastuvka, J, Macel, I, Navratil, K, Gregor, P, Lacnak, B, Janousek, J, Kellnerova, I, Hulinsky, V, Matusek, Z, Prucek, L, Dunaj, M, Pirchala, M, Vencour, D, Pavolko, M, Gorican, K, Fiksa, J, Tuxen, C, Meyer, C, Suppli Ulrik, C, Uuetoa, T, Otarishvili, N, Khintibidze, I, Emukhvari, N, Kipiani, Z, Gochitashvili, D, Mamatsashvili, M, Megreladze, I, Paposhvili, K, Agladze, R, Eradze, Z, Chelidze, K, Lominadze, S, Chukhrukidze, A, Chumburidze, V, Metreveli, S, Danelia, V, Orjonikidze, S, Kobulia, B, Nikolaishvili, G, Gvenetadze, R, Melia, A, Tsinamdzgvrishvili, B, Sekhniashvili, M, Sikharulidze, I, Meuser, M, Licka, M, Rauch-Kroehnert, U, Graf, K, Brachmann, J, Akin, I, Toumbis, M, Vassilikos, V, Konstantinides, S, Steiropoulos, P, Gogos, C, Andrikopoulos, G, Parthenakis, F, Karydi, P, Tsivgoulis, G, Mertzanos, G, Olympios, C, Karapanayiotides, T, Paraskevopoulou, E, Kifnidis, K, Hahalis, G, Skoutelis, A, Vadikolias, K, Nyirati, G, Nagy, L, Matoltsy, A, Komoly, S, Lippai, J, Kiss, K, Toth, K, Pozsegovits, K, Kiraly, C, Bereczki, D, Zolyomi, S, Szakal, I, Pall, D, Futo, L, Forster, T, Lovasz, O, Papp, A, Kiraly, Z, Pozsonyi, Z, Hajko, E, Kristof, P, Lakatos, F, Ples, Z, Kirschner, R, Lupkovics, G, Timar, G, Pinter, I, Kristof, T, Kis, E, Kovacs, A, Jakab, G, Palinkas, A, Muller, G, Turi, T, Horvath, C, Kondakor, I, Csanyi, A, Frankfurter, Z, Gurzo, M, Gafter-Gvili, A, Kuchuk, M, Azzam, Z, Elis, A, Halabi, M, Hussein, O, Blum, A, Tsoran-Rosenthal, I, Lishner, M, Hochberg-Klein, S, Caraco, Y, Atar, S, Elias, N, Gavish, D, Butnaru, A, Cosmi, F, Garbelotto, R, Giorgi Pierfranceschi, M, Simioni, L, Gronda, E, Pesci, A, D'Angelo, A, Fedele, F, Ghirarduzzi, A, Piovaccari, G, Lembo, G, Ria, L, Monaco, G, Brunelli, C, Tosetto, A, Capucci, A, Zanatta, N, Pistolesi, M, Mazzi, V, Testa, S, Scherillo, M, Di Biase, M, Antonicelli, R, Lodigiani, C, Nassiacos, D, Viksne, I, Lapkovska, Z, Rancane, G, Sime, I, Pontaga, N, Eglite, R, Puzule, S, Smolova, R, Butkiene, Z, Bagdonas, A, Raugaliene, R, Norkiene, S, Norviliene, R, Basijokiene, V, Stonkus, S, Griskeviciene, V, Miskiniene, A, Norvaisiene, R, Skripkauskiene, I, Jovkovska-Kaeva, B, Kochovska-Kamchevska, N, Antovski, A, Nechevska, L, Celeska, V, Ilievska-Poposka, B, Kostojchinoska, M, Donchovska, S, Kedev, S, Kuzmanovski, I, Bushletikj, O, Stojchev, S, Bakrachevski, N, Kuzmanovska, B, Angusheva, T, Llamas Esperon, G, Valdez Lopez, H, Medina Pech, C, Cortes Hernandez, M, Gans, S, Smulders, S, Swart, H, Boersma, W, Goosens, M, Hovens, M, Semplonius, G, Sohne, M, Lema Osores, J, Salas Perez, M, Rodriguez, A, Rios Oliva, C, Cotrina, R, Berrospi Argandona, P, Toce Yanez, L, Chavez Ayala, C, Mirek-Bryniarska, E, Goch, A, Skucha, W, Skorski, M, Miekus, P, Szyszka, A, Piotrowski, G, Gniot, J, Czerski, T, Debich, P, Zaluska, R, Bebenek, W, Wozakowska-Kaplon, B, Sciborski, R, Ilkowski, J, Wojnowski, P, Uscinska, E, Gaciong, Z, Bonek, R, Sobkowicz, B, Berkowski, P, Bejgier, K, Polonski, L, Kosior, D, Lata, S, Kolodziej, P, Gessek, J, Kachel, T, Talalaj, M, Musial, J, Lewczuk, J, Krysiak, W, Kucharski, L, Wysokinski, A, Minc, P, Martinez, J, Gregorio, T, Almeida, F, Monteiro, P, Stanciulescu, G, Mercea, C, Iosipescu, L, Ciobotaru, V, Crisu, D, Burca, M, Tudoran, M, Savu, A, Negrean, V, Cojocaru, C, Minescu, B, Popa, V, Blajan, D, Nastase-Melicovici, D, Fruntelata, A, Barbulescu, S, Lukinyh, L, Akhunova, S, Vishneva, E, Semenova, I, Nikolaev, K, Shaydyuk, O, Nilk, R, Shalnev, V, Apartsin, K, Goloshchekin, B, Shpagina, L, Khlevchuk, T, Arkhipov, M, Malygin, A, Shvarts, Y, Khaisheva, L, Popov, D, Kobalava, Z, Lipchenko, A, Shapovalova, Y, Zrazhevsky, K, Greshnova, I, Maslova, N, Karabenenko, A, Shogenov, Z, Budankova, E, Barbarash, O, Uspenskiy, Y, Kosmacheva, E, Berns, S, Kostenko, V, Zateyshchikov, D, Vishnevsky, A, Boldueva, S, Podzolkov, V, Sergeeva, E, Grinshtein, Y, Khrustalev, O, Bugrova, O, Repin, A, Andreev, D, Petrovic, P, Boskovic Matic, T, Apostolovic, S, Lazic, Z, Stankovic, D, Stankovic, A, Mitov, V, Sofronic, D, Kopitovic, I, Zdravkovic, V, Joksimovic, Z, Lazovic, N, Petrovic-Stanojevic, N, Ilic, A, Vujadinovic, O, Pencic-Popovic, B, Andjelkovic, N, Sekularac, N, Hinic, S, Radjen, G, Zivkovic, A, Putnikovic, B, Ivanov, I, Babic, R, Van Zyl, L, Hobson, B, Engelbrecht, J, Mitha, I, Siebert, H, Jacobson, B, Breedt, J, Prozesky, H, Ntsekhe, M, Bayat, J, Ellis, G, Tarr, G, Adler, D, Van Dyk, C, Ismail, S, Spargo, C, Abdool-Gaffar, M, Saaiman, J, Venter, K, Lorente Aroca, M, Fernandez Portales, F, Pedrajas Navas, J, Rodriguez Botaro, A, Santa Cruz Siminiani, A, Lopez Reyes, R, Bisbe i Company, J, Piedecausa Selfa, M, Velasco Garrido, J, Sobrino-Martinez, J, Munoz Delgado, G, Sala Llinas, E, Blanco Coronado, J, Almenar Bonet, L, Vida Gutierrez, M, Sanchez Lora, F, Sanchez Martinez, R, Calderon, E, Villalta Blanch, J, De la Hera Galarza, J, Bustamante Ruiz, A, Garcia-Fuster, M, Ripoll Vera, T, Alvarez-Sala Walter, L, Todoli Parra, J, Diaz Fernandez, J, Bosa Ojeda, F, Pellicer-Ciscar, C, Jara Palomares, L, Quiles Granado, J, Trigo Bautista, A, Ruiz Bustillo, S, Ordi Ros, J, Tolosa-Vilella, C, Marin Ortuno, F, Garcia Sanchez, F, Barba Martin, R, Segovia Cubero, J, Cuervas-Mons Martinez, V, Galan Montejano, M, Lopez Meseguer, M, Sener Comert, S, Koksal, N, Tertemiz, K, Ernam, D, Dursun, A, Yildiz, O, Rudenko, L, Abrahamovych, O, Goloborodko, A, Holovchenko, N, Kulyk, A, Yagensky, A, Batushkin, V, Zolotaikina, V, Kozyolkin, O, Faynyk, A, Maslovskyy, V, Petrovskyy, R, Koshlia, V, Chopey, I, Burmak, I, Malynovsky, Y, Voronkov, L, Karpenko, O, Dziublyk, O, Godlevska, O, Borovyk, V, Bezrodna, L, Serik, S, Ovsyannikova, N, Vynnychenko, L, Kopytsya, M, Rudkovskiy, V, Grishyna, O, Vyshnyvetskyy, I, Prystupa, L, Tseluyko, V, Perepeliuk, M, Koval, O, Sychov, O, Church, A, Goudie, A, Elliott, M, Ferguson, C, Welker, J, Kao, C, Bhagwat, R, Serota, H, Bozorgchami, H, Nambiar, R, Spilseth, S, Bhagwath, G, Syed, F, Morrow, L, Updegrove, J, Bercz, P, Kambo, V, Henderson, D, Wright, P, Dang, N, Nadar, V, Jaffrani, N, El-Shahawy, M, Grossman, C, Pearle, J, Weinstein, D, Galanis, T, Gazmuri, R, Kastelic, R, Martinez, R, Laman, D, Macchiavelli, A, Kmetzo, J, Thurm, C, Kayembe, T, Chandrashekhar, Y, Bassetti, D, Jaoude, P, Williams, H, Dewhurst, R, Naqvi, S, Burr, J, Rodriguez-Cintron, W, Jeanfreau, R, Kosinski, E, Ndukwu, I, Sotolongo, C, Daboul, N, Wilmer, C, Simon, P, Tak, T, Rees, C, Gupta, N, Lerner, R, Graffagnino, C, Reed, R, Alford, C, Mody, F, Wellmon, B, Hamroff, G, Rajan, R, Kaatz, S, Spyropoulos A. C., Ageno W., Albers G. W., Elliott C. G., Halperin J. L., Hiatt W. R., Maynard G. A., Steg P. G., Weitz J. I., Suh E., Spiro T. E., Barnathan E. S., Raskob G. E., Douketis J., Turpie A. G., Schulman S., Kearon C., Linkins L. A., Schellong S., Bauer K., Geerts W., Roberts R., Casais P., Gallus A., Karrasch J., Eichinger-Hasenauer S., Krivenchuk V., Hadzovic-Dzuvo A., Trbojevic S., Lopes R., Mincheva V., Carrier M., Dennis R., Tudoric N., Spinar J., Nielsen H., Marandi T., Shaburishvili T., Beyer-Westendorf J., Vardas P., Boda Z., Brenner B., Piovella F., Krievins D., Petrauskiene B., Dejanova-Ilijevska V., Virgen Carrillo L. R., Middeldorp S., Castillo Leon R. P., Torbicki A., Saraiva de Sousa M., Dorobantu M., Militaru C., Yavelov I., Vuckovic B., Reuter H., Basson M., Monreal M., Kucukoglu S., Parkhomenko A., Alikhan R., Rosenberg D., Yusen R., Khorana A., Tapson V., Pollack C., Hazelrigg M., Jure H., Alvarisqueta A., Cartasegna L., Hominal M., Cursack G., Alzogaray M., Maillo M., Parody M., Caccavo A., Dran R. D., Muntaner J. A., Casas M., Schmidberg J., Sarjanovich R., Gabito A., Garrido M., Amuchastegui M., Fernandez A., Loureyro J., Giumelli C., Heazlewood V., Colquhoun D., White H., Sabet A., Bowler S., Carroll P., Khalafallah A., Baker R., Hedger S., Simpson F. G., Jackson D., Chong B., Siostrzonek P., Gary T., Hoppe U., Dosta N., Prystrom A., Gorokhovsky S., Yanushko V., Skrahin A., Kulik A., Maslianski B., Yakubtsevich R., Timkin I., Moguchaya O., Tanaskovic N., Miljkovic S., Stojkovic S., Kovacevic-Preradovic T., Jovic D., Basagic E., Radjen M., Mutapcic M., Rizvanovic-Vojic E., Galic K., Terzic I., Pojskic B., Stevanovic D., Cehajic M., Rech R., Annichino-Bizzacchi J., Stelmach R., Blanco D., Castro I., Backes L. M., Saraiva J. F., Ramacciotti E., de Barros e Silva P. G. M., Reis G., Moreira Vieira E., Leaes P., Zimmermann S., Van Bellen B., Precoma D., Luiz Silvestrini T., Hernandes M. E., Kyoleyan M., Kalinova T., Tiholov R., Petrov I., Mihov A., Chompalova B., Velikov C., Pencheva G., Atanasov P., Raev D., Kinova E., Peltegov V., Marchev S., Siulemezova S., Ayryanova I. D., Grigorov M., Naydenova I., Koteva N., Dimov B., Runev N., Getov D., Metev H., Donchev K., Taseva M., Hadzhieva A., Benov H., Stoyanov M., Tisheva-Gospodinova S., Mihaylova N., Abadzhiev S., Atzev B., Georgiev R., Mollov M., Stoikov A., Mazhdrakov G., Karastanev K., Dube F., Roth S., Mansour S., Wu C., Dolan S., Pesant Y., Pietrangelo M., Dresser G., Kahn S., Kruisselbrink R., Cadena Bonfanti A., Botero R., Quintero Ossa A., Poveda C. M., Cedano J., Gomez Isaza L., Villaquiran Torres C., Gomez Mesa J., Vargas Alonso R., Espinosa D., Rodriguez J. M., Sanchez G., Accini Mendoza J. L., Gomez Florez C. C., Cuervo Millan F., Pesek K., Horvat D., Fuckar K., Ruzic A., Ostricki B., Knezevic A., Breitenfeld T., Laganovic M., Samodol A., Sikic J., Starcevic B., Babic Z., Samarzija M., Milas K., Votocek S., Kvapil M., Kolman P., Bindas P., Simon V., Adamek T., Svobodova J., Gergely L., Lastuvka J., Macel I., Navratil K., Gregor P., Lacnak B., Janousek J., Kellnerova I., Hulinsky V., Matusek Z., Prucek L., Dunaj M., Pirchala M., Vencour D., Pavolko M., Gorican K., Fiksa J., Tuxen C., Meyer C., Suppli Ulrik C., Uuetoa T., Otarishvili N., Khintibidze I., Emukhvari N., Kipiani Z., Gochitashvili D., Mamatsashvili M., Megreladze I., Paposhvili K., Agladze R., Eradze Z., Chelidze K., Lominadze S., Chukhrukidze A., Chumburidze V., Metreveli S., Danelia V., Orjonikidze S., Kobulia B., Nikolaishvili G., Gvenetadze R., Melia A., Tsinamdzgvrishvili B., Sekhniashvili M., Sikharulidze I., Meuser M., Licka M., Rauch-Kroehnert U., Graf K., Brachmann J., Akin I., Toumbis M., Vassilikos V., Konstantinides S., Steiropoulos P., Gogos C., Andrikopoulos G., Parthenakis F., Karydi P., Tsivgoulis G., Mertzanos G., Olympios C., Karapanayiotides T., Paraskevopoulou E., Kifnidis K., Hahalis G., Skoutelis A., Vadikolias K., Nyirati G., Nagy L., Matoltsy A., Komoly S., Lippai J., Kiss K., Toth K., Pozsegovits K., Kiraly C., Bereczki D., Zolyomi S., Szakal I., Pall D., Futo L., Forster T., Lovasz O., Papp A., Kiraly Z., Pozsonyi Z., Hajko E., Kristof P., Lakatos F., Ples Z., Kirschner R., Lupkovics G., Timar G., Pinter I., Kristof T., Kis E., Kovacs A., Jakab G., Palinkas A., Muller G., Turi T., Horvath C., Kondakor I., Csanyi A., Frankfurter Z., Gurzo M., Gafter-Gvili A., Kuchuk M., Azzam Z., Elis A., Halabi M., Hussein O., Blum A., Tsoran-Rosenthal I., Lishner M., Hochberg-Klein S., Caraco Y., Atar S., Elias N., Gavish D., Butnaru A., Cosmi F., Garbelotto R., Giorgi Pierfranceschi M., Simioni L., Gronda E., Pesci A., D'Angelo A., Fedele F., Ghirarduzzi A., Piovaccari G., Lembo G., Ria L., Monaco G. L., Brunelli C., Tosetto A., Capucci A., Zanatta N., Pistolesi M., Mazzi V., Testa S., Scherillo M., Di Biase M., Antonicelli R., Lodigiani C., Nassiacos D., Viksne I., Lapkovska Z., Rancane G., Sime I., Pontaga N., Eglite R., Puzule S., Smolova R., Butkiene Z., Bagdonas A., Raugaliene R., Norkiene S., Norviliene R., Basijokiene V., Stonkus S., Griskeviciene V., Miskiniene A., Norvaisiene R., Skripkauskiene I., Jovkovska-Kaeva B., Kochovska-Kamchevska N., Antovski A., Nechevska L., Celeska V., Ilievska-Poposka B., Kostojchinoska M., Donchovska S., Kedev S., Kuzmanovski I., Bushletikj O., Stojchev S., Bakrachevski N., Kuzmanovska B., Angusheva T., Llamas Esperon G., Valdez Lopez H., Medina Pech C., Cortes Hernandez M., Virgen Carrillo L., Gans S., Smulders S., Swart H., Boersma W., Goosens M., Hovens M., Semplonius G., Sohne M., Lema Osores J., Salas Perez M. D., Rodriguez A., Rios Oliva C., Cotrina R., Berrospi Argandona P., Toce Yanez L., Chavez Ayala C., Mirek-Bryniarska E., Goch A., Skucha W., Skorski M., Miekus P., Szyszka A., Piotrowski G., Gniot J., Czerski T., Debich P., Zaluska R., Bebenek W., Wozakowska-Kaplon B., Sciborski R., Ilkowski J., Wojnowski P., Uscinska E., Gaciong Z., Bonek R., Sobkowicz B., Berkowski P., Bejgier K., Polonski L., Kosior D., Lata S., Kolodziej P., Gessek J., Kachel T., Talalaj M., Musial J., Lewczuk J., Krysiak W., Kucharski L., Wysokinski A., Minc P., Martinez J., Gregorio T., Almeida F., Monteiro P., Stanciulescu G., Mercea C. D., Iosipescu L. C., Ciobotaru V., Crisu D., Burca M., Tudoran M., Savu A., Negrean V., Cojocaru C., Minescu B., Popa V., Blajan D., Nastase-Melicovici D., Fruntelata A., Barbulescu S., Lukinyh L., Akhunova S., Vishneva E., Semenova I., Nikolaev K. Y., Shaydyuk O., Nilk R., Shalnev V., Apartsin K., Goloshchekin B. M., Shpagina L., Khlevchuk T., Arkhipov M., Malygin A., Shvarts Y., Khaisheva L., Popov D., Kobalava Z., Lipchenko A., Shapovalova Y., Zrazhevsky K., Greshnova I., Maslova N., Karabenenko A., Shogenov Z., Budankova E., Barbarash O., Uspenskiy Y., Kosmacheva E., Berns S., Kostenko V., Zateyshchikov D., Vishnevsky A., Boldueva S., Podzolkov V., Sergeeva E., Grinshtein Y., Khrustalev O., Bugrova O., Repin A., Andreev D., Petrovic P., Boskovic Matic T., Apostolovic S., Lazic Z., Stankovic D., Stankovic A., Mitov V., Sofronic D., Kopitovic I., Zdravkovic V., Joksimovic Z., Lazovic N., Petrovic-Stanojevic N., Ilic A., Vujadinovic O., Pencic-Popovic B., Andjelkovic N., Sekularac N., Hinic S., Radjen G., Zivkovic A., Putnikovic B., Ivanov I., Babic R., Van Zyl L., Hobson B., Engelbrecht J., Mitha I., Siebert H., Jacobson B., Breedt J., Prozesky H., Ntsekhe M., Bayat J., Ellis G., Tarr G., Adler D., Van Dyk C., Ismail S. M., Spargo C. E., Abdool-Gaffar M., Saaiman J., Venter K., Lorente Aroca M. L., Fernandez Portales F., Pedrajas Navas J., Rodriguez Botaro A., Santa Cruz Siminiani A., Lopez Reyes R., Bisbe i Company J., Piedecausa Selfa M., Velasco Garrido J., Sobrino-Martinez J., Munoz Delgado G., Sala Llinas E., Blanco Coronado J., Almenar Bonet L., Vida Gutierrez M., Sanchez Lora F., Sanchez Martinez R., Calderon E. J., Villalta Blanch J., De la Hera Galarza J. M., Bustamante Ruiz A., Garcia-Fuster M. J., Ripoll Vera T., Alvarez-Sala Walter L., Todoli Parra J. A., Diaz Fernandez J., Bosa Ojeda F., Pellicer-Ciscar C., Jara Palomares L., Quiles Granado J., Trigo Bautista A., Ruiz Bustillo S., Ordi Ros J., Tolosa-Vilella C., Marin Ortuno F., Garcia Sanchez F., Barba Martin R., Segovia Cubero J., Cuervas-Mons Martinez V., Galan Montejano M., Lopez Meseguer M., Sener Comert S., Koksal N., Tertemiz K., Ernam D., Dursun A. B., Yildiz O., Rudenko L., Abrahamovych O., Goloborodko A., Holovchenko N., Kulyk A., Yagensky A., Batushkin V., Zolotaikina V., Kozyolkin O., Faynyk A., Maslovskyy V., Petrovskyy R., Koshlia V., Chopey I., Burmak I., Malynovsky Y., Voronkov L., Karpenko O., Dziublyk O., Godlevska O., Borovyk V., Bezrodna L., Serik S., Ovsyannikova N., Vynnychenko L., Kopytsya M., Rudkovskiy V., Grishyna O., Vyshnyvetskyy I., Prystupa L., Tseluyko V., Perepeliuk M., Koval O., Sychov O., Church A., Goudie A., Elliott M., Ferguson C., Welker J., Kao C. K., Bhagwat R., Serota H., Bozorgchami H., Nambiar R., Spilseth S., Bhagwath G., Syed F., Morrow L., Updegrove J., Bercz P., Kambo V., Henderson D., Wright P., Dang N., Nadar V., Jaffrani N., El-Shahawy M., Grossman C. H., Pearle J., Weinstein D., Galanis T. P., Gazmuri R., Kastelic R., Martinez R., Laman D., Macchiavelli A., Kmetzo J., Thurm C., Kayembe T., Chandrashekhar Y., Bassetti D., Jaoude P., Williams H., Dewhurst R., Naqvi S., Burr J., Rodriguez-Cintron W., Jeanfreau R., Kosinski E., Ndukwu I. M., Sotolongo C., Daboul N., Wilmer C., Simon P., Tak T., Rees C., Gupta N., Lerner R., Graffagnino C., Reed R. M., Alford C. M., Mody F., Wellmon B., Hamroff G., Rajan R., and Kaatz S.
- Abstract
BACKGROUND Patients who are hospitalized for medical illness remain at risk for venous thromboembolism after discharge, but the role of extended thromboprophylaxis in the treatment of such patients is a subject of controversy. METHODS In this randomized, double-blind trial, medically ill patients who were at increased risk for venous thromboembolism on the basis of a modified International Medical Prevention Registry on Venous Thromboembolism (IMPROVE) score of 4 or higher (scores range from 0 to 10, with higher scores indicating a higher risk of venous thromboembolism) or a score of 2 or 3 plus a plasma d-dimer level of more than twice the upper limit of the normal range (defined according to local laboratory criteria) were assigned at hospital discharge to either once-daily rivaroxaban at a dose of 10 mg (with the dose adjusted for renal insufficiency) or placebo for 45 days. The primary efficacy outcome was a composite of symptomatic venous thromboembolism or death due to venous thromboembolism. The principal safety outcome was major bleeding. RESULTS Of the 12,024 patients who underwent randomization, 12,019 were included in the intention-to-treat analysis. The primary efficacy outcome occurred in 50 of 6007 patients (0.83%) who were given rivaroxaban and in 66 of 6012 patients (1.10%) who were given placebo (hazard ratio, 0.76; 95% confidence interval [CI], 0.52 to 1.09; P = 0.14). The prespecified secondary outcome of symptomatic nonfatal venous thromboembolism occurred in 0.18% of patients in the rivaroxaban group and 0.42% of patients in the placebo group (hazard ratio, 0.44; 95% CI, 0.22 to 0.89). Major bleeding occurred in 17 of 5982 patients (0.28%) in the rivaroxaban group and in 9 of 5980 patients (0.15%) in the placebo group (hazard ratio, 1.88; 95% CI, 0.84 to 4.23). CONCLUSIONS Rivaroxaban, given to medical patients for 45 days after hospital discharge, was not associated with a significantly lower risk of symptomatic venous thromboembolism and death
- Published
- 2018
23. Paraprosthetic Complications After Endoprosthesis Replacement of Pelvis Joint with Implants
- Author
-
Alexey A. Dolgov, Serik S. Balgazarov, Shalginbay A. Baimagambetov, Zhanatay K. Ramazanov, Ruslan S. Abilov, Yelena A. Belan, and Amangol S. Balgazarov
- Subjects
Adult ,Male ,Reoperation ,medicine.medical_specialty ,0206 medical engineering ,Population ,Bone Neoplasms ,Context (language use) ,02 engineering and technology ,Prosthesis Design ,Social issues ,03 medical and health sciences ,Postoperative Complications ,0302 clinical medicine ,Health care ,Health insurance ,Humans ,Medicine ,Operations management ,Arthroplasty, Replacement ,Pelvic Bones ,education ,Social policy ,030222 orthopedics ,education.field_of_study ,business.industry ,Prostheses and Implants ,General Medicine ,General insurance ,020601 biomedical engineering ,Prosthesis Failure ,Surgery ,Black or African American ,Radiography ,Pelvis joint ,Outcome and Process Assessment, Health Care ,Female ,Hip Joint ,Joints ,business - Abstract
Purpose The purpose of the paper is shaping of ideas about possible ways of decreasing complications of the analyzed types of operations and identification of opportunities of the impact on the socio-economic environment among the Afro-American population of USA. The paper demonstrates that the issue of coxofemoral prosthesis is not only a purely medical but also a social problem. In particular, availability of timely aid, as well as insurance in the form of surgery, refer to relevance of the range of problems. Methodology The experimental method was used in the study. Patients were implanted different types of endoprostheses. 90 patients were implanted customized endoprostheses, 27 patients were implanted foreign module endoprostheses. The research subject is prediction of complications after endoprosthesis replacement surgeries depending on methods, types and forms. Results As a result, we can see that available health insurance is more acceptable understanding of the need for endoprosthesis replacement. Post-operative care issues fall into the range of social policy problems. A comparative aspect of a country with general insurance and differentiated coverage among the Afro-America population appears innovative. Conclusions In the context of the current situation it can be concluded that surgery is the last stage for already established support system of the population. For this reason, it's worth mentioning that state bodies of the U.S. should put a greater emphasis on the health care of the Afro-American population.
- Published
- 2018
24. Rivaroxaban for Thromboprophylaxis after Hospitalization for Medical Illness
- Author
-
Spyropoulos A. C., Ageno W., Albers G. W., Elliott C. G., Halperin J. L., Hiatt W. R., Maynard G. A., Steg P. G., Weitz J. I., Suh E., Spiro T. E., Barnathan E. S., Raskob G. E., Douketis J., Turpie A. G., Schulman S., Kearon C., Linkins L. A., Schellong S., Bauer K., Geerts W., Roberts R., Casais P., Gallus A., Karrasch J., Eichinger-Hasenauer S., Krivenchuk V., Hadzovic-Dzuvo A., Trbojevic S., Lopes R., Mincheva V., Carrier M., Dennis R., Tudoric N., Spinar J., Nielsen H., Marandi T., Shaburishvili T., Beyer-Westendorf J., Vardas P., Boda Z., Brenner B., Piovella F., Krievins D., Petrauskiene B., Dejanova-Ilijevska V., Virgen Carrillo L. R., Middeldorp S., Castillo Leon R. P., Torbicki A., Saraiva de Sousa M., Dorobantu M., Militaru C., Yavelov I., Vuckovic B., Reuter H., Basson M., Monreal M., Kucukoglu S., Parkhomenko A., Alikhan R., Rosenberg D., Yusen R., Khorana A., Tapson V., Pollack C., Hazelrigg M., Jure H., Alvarisqueta A., Cartasegna L., Hominal M., Cursack G., Alzogaray M., Maillo M., Parody M., Caccavo A., Dran R. D., Muntaner J. A., Casas M., Schmidberg J., Sarjanovich R., Gabito A., Garrido M., Amuchastegui M., Fernandez A., Loureyro J., Giumelli C., Heazlewood V., Colquhoun D., White H., Sabet A., Bowler S., Carroll P., Khalafallah A., Baker R., Hedger S., Simpson F. G., Jackson D., Chong B., Siostrzonek P., Gary T., Hoppe U., Dosta N., Prystrom A., Gorokhovsky S., Yanushko V., Skrahin A., Kulik A., Maslianski B., Yakubtsevich R., Timkin I., Moguchaya O., Tanaskovic N., Miljkovic S., Stojkovic S., Kovacevic-Preradovic T., Jovic D., Basagic E., Radjen M., Mutapcic M., Rizvanovic-Vojic E., Galic K., Terzic I., Pojskic B., Stevanovic D., Cehajic M., Rech R., Annichino-Bizzacchi J., Stelmach R., Blanco D., Castro I., Backes L. M., Saraiva J. F., Ramacciotti E., de Barros e Silva P. G. M., Reis G., Moreira Vieira E., Leaes P., Zimmermann S., Van Bellen B., Precoma D., Luiz Silvestrini T., Hernandes M. E., Kyoleyan M., Kalinova T., Tiholov R., Petrov I., Mihov A., Chompalova B., Velikov C., Pencheva G., Atanasov P., Raev D., Kinova E., Peltegov V., Marchev S., Siulemezova S., Ayryanova I. D., Grigorov M., Naydenova I., Koteva N., Dimov B., Runev N., Getov D., Metev H., Donchev K., Taseva M., Hadzhieva A., Benov H., Stoyanov M., Tisheva-Gospodinova S., Mihaylova N., Abadzhiev S., Atzev B., Georgiev R., Mollov M., Stoikov A., Mazhdrakov G., Karastanev K., Dube F., Roth S., Mansour S., Wu C., Dolan S., Pesant Y., Pietrangelo M., Dresser G., Kahn S., Kruisselbrink R., Cadena Bonfanti A., Botero R., Quintero Ossa A., Poveda C. M., Cedano J., Gomez Isaza L., Villaquiran Torres C., Gomez Mesa J., Vargas Alonso R., Espinosa D., Rodriguez J. M., Sanchez G., Accini Mendoza J. L., Gomez Florez C. C., Cuervo Millan F., Pesek K., Horvat D., Fuckar K., Ruzic A., Ostricki B., Knezevic A., Breitenfeld T., Laganovic M., Samodol A., Sikic J., Starcevic B., Babic Z., Samarzija M., Milas K., Votocek S., Kvapil M., Kolman P., Bindas P., Simon V., Adamek T., Svobodova J., Gergely L., Lastuvka J., Macel I., Navratil K., Gregor P., Lacnak B., Janousek J., Kellnerova I., Hulinsky V., Matusek Z., Prucek L., Dunaj M., Pirchala M., Vencour D., Pavolko M., Gorican K., Fiksa J., Tuxen C., Meyer C., Suppli Ulrik C., Uuetoa T., Otarishvili N., Khintibidze I., Emukhvari N., Kipiani Z., Gochitashvili D., Mamatsashvili M., Megreladze I., Paposhvili K., Agladze R., Eradze Z., Chelidze K., Lominadze S., Chukhrukidze A., Chumburidze V., Metreveli S., Danelia V., Orjonikidze S., Kobulia B., Nikolaishvili G., Gvenetadze R., Melia A., Tsinamdzgvrishvili B., Sekhniashvili M., Sikharulidze I., Meuser M., Licka M., Rauch-Kroehnert U., Graf K., Brachmann J., Akin I., Toumbis M., Vassilikos V., Konstantinides S., Steiropoulos P., Gogos C., Andrikopoulos G., Parthenakis F., Karydi P., Tsivgoulis G., Mertzanos G., Olympios C., Karapanayiotides T., Paraskevopoulou E., Kifnidis K., Hahalis G., Skoutelis A., Vadikolias K., Nyirati G., Nagy L., Matoltsy A., Komoly S., Lippai J., Kiss K., Toth K., Pozsegovits K., Kiraly C., Bereczki D., Zolyomi S., Szakal I., Pall D., Futo L., Forster T., Lovasz O., Papp A., Kiraly Z., Pozsonyi Z., Hajko E., Kristof P., Lakatos F., Ples Z., Kirschner R., Lupkovics G., Timar G., Pinter I., Kristof T., Kis E., Kovacs A., Jakab G., Palinkas A., Muller G., Turi T., Horvath C., Kondakor I., Csanyi A., Frankfurter Z., Gurzo M., Gafter-Gvili A., Kuchuk M., Azzam Z., Elis A., Halabi M., Hussein O., Blum A., Tsoran-Rosenthal I., Lishner M., Hochberg-Klein S., Caraco Y., Atar S., Elias N., Gavish D., Butnaru A., Cosmi F., Garbelotto R., Giorgi Pierfranceschi M., Simioni L., Gronda E., Pesci A., D'Angelo A., Fedele F., Ghirarduzzi A., Piovaccari G., Lembo G., Ria L., Monaco G. L., Brunelli C., Tosetto A., Capucci A., Zanatta N., Pistolesi M., Mazzi V., Testa S., Scherillo M., Di Biase M., Antonicelli R., Lodigiani C., Nassiacos D., Viksne I., Lapkovska Z., Rancane G., Sime I., Pontaga N., Eglite R., Puzule S., Smolova R., Butkiene Z., Bagdonas A., Raugaliene R., Norkiene S., Norviliene R., Basijokiene V., Stonkus S., Griskeviciene V., Miskiniene A., Norvaisiene R., Skripkauskiene I., Jovkovska-Kaeva B., Kochovska-Kamchevska N., Antovski A., Nechevska L., Celeska V., Ilievska-Poposka B., Kostojchinoska M., Donchovska S., Kedev S., Kuzmanovski I., Bushletikj O., Stojchev S., Bakrachevski N., Kuzmanovska B., Angusheva T., Llamas Esperon G., Valdez Lopez H., Medina Pech C., Cortes Hernandez M., Virgen Carrillo L., Gans S., Smulders S., Swart H., Boersma W., Goosens M., Hovens M., Semplonius G., Sohne M., Lema Osores J., Salas Perez M. D., Rodriguez A., Rios Oliva C., Cotrina R., Berrospi Argandona P., Toce Yanez L., Chavez Ayala C., Mirek-Bryniarska E., Goch A., Skucha W., Skorski M., Miekus P., Szyszka A., Piotrowski G., Gniot J., Czerski T., Debich P., Zaluska R., Bebenek W., Wozakowska-Kaplon B., Sciborski R., Ilkowski J., Wojnowski P., Uscinska E., Gaciong Z., Bonek R., Sobkowicz B., Berkowski P., Bejgier K., Polonski L., Kosior D., Lata S., Kolodziej P., Gessek J., Kachel T., Talalaj M., Musial J., Lewczuk J., Krysiak W., Kucharski L., Wysokinski A., Minc P., Martinez J., Gregorio T., Almeida F., Monteiro P., Stanciulescu G., Mercea C. D., Iosipescu L. C., Ciobotaru V., Crisu D., Burca M., Tudoran M., Savu A., Negrean V., Cojocaru C., Minescu B., Popa V., Blajan D., Nastase-Melicovici D., Fruntelata A., Barbulescu S., Lukinyh L., Akhunova S., Vishneva E., Semenova I., Nikolaev K. Y., Shaydyuk O., Nilk R., Shalnev V., Apartsin K., Goloshchekin B. M., Shpagina L., Khlevchuk T., Arkhipov M., Malygin A., Shvarts Y., Khaisheva L., Popov D., Kobalava Z., Lipchenko A., Shapovalova Y., Zrazhevsky K., Greshnova I., Maslova N., Karabenenko A., Shogenov Z., Budankova E., Barbarash O., Uspenskiy Y., Kosmacheva E., Berns S., Kostenko V., Zateyshchikov D., Vishnevsky A., Boldueva S., Podzolkov V., Sergeeva E., Grinshtein Y., Khrustalev O., Bugrova O., Repin A., Andreev D., Petrovic P., Boskovic Matic T., Apostolovic S., Lazic Z., Stankovic D., Stankovic A., Mitov V., Sofronic D., Kopitovic I., Zdravkovic V., Joksimovic Z., Lazovic N., Petrovic-Stanojevic N., Ilic A., Vujadinovic O., Pencic-Popovic B., Andjelkovic N., Sekularac N., Hinic S., Radjen G., Zivkovic A., Putnikovic B., Ivanov I., Babic R., Van Zyl L., Hobson B., Engelbrecht J., Mitha I., Siebert H., Jacobson B., Breedt J., Prozesky H., Ntsekhe M., Bayat J., Ellis G., Tarr G., Adler D., Van Dyk C., Ismail S. M., Spargo C. E., Abdool-Gaffar M., Saaiman J., Venter K., Lorente Aroca M. L., Fernandez Portales F., Pedrajas Navas J., Rodriguez Botaro A., Santa Cruz Siminiani A., Lopez Reyes R., Bisbe i Company J., Piedecausa Selfa M., Velasco Garrido J., Sobrino-Martinez J., Munoz Delgado G., Sala Llinas E., Blanco Coronado J., Almenar Bonet L., Vida Gutierrez M., Sanchez Lora F., Sanchez Martinez R., Calderon E. J., Villalta Blanch J., De la Hera Galarza J. M., Bustamante Ruiz A., Garcia-Fuster M. J., Ripoll Vera T., Alvarez-Sala Walter L., Todoli Parra J. A., Diaz Fernandez J., Bosa Ojeda F., Pellicer-Ciscar C., Jara Palomares L., Quiles Granado J., Trigo Bautista A., Ruiz Bustillo S., Ordi Ros J., Tolosa-Vilella C., Marin Ortuno F., Garcia Sanchez F., Barba Martin R., Segovia Cubero J., Cuervas-Mons Martinez V., Galan Montejano M., Lopez Meseguer M., Sener Comert S., Koksal N., Tertemiz K., Ernam D., Dursun A. B., Yildiz O., Rudenko L., Abrahamovych O., Goloborodko A., Holovchenko N., Kulyk A., Yagensky A., Batushkin V., Zolotaikina V., Kozyolkin O., Faynyk A., Maslovskyy V., Petrovskyy R., Koshlia V., Chopey I., Burmak I., Malynovsky Y., Voronkov L., Karpenko O., Dziublyk O., Godlevska O., Borovyk V., Bezrodna L., Serik S., Ovsyannikova N., Vynnychenko L., Kopytsya M., Rudkovskiy V., Grishyna O., Vyshnyvetskyy I., Prystupa L., Tseluyko V., Perepeliuk M., Koval O., Sychov O., Church A., Goudie A., Elliott M., Ferguson C., Welker J., Kao C. K., Bhagwat R., Serota H., Bozorgchami H., Nambiar R., Spilseth S., Bhagwath G., Syed F., Morrow L., Updegrove J., Bercz P., Kambo V., Henderson D., Wright P., Dang N., Nadar V., Jaffrani N., El-Shahawy M., Grossman C. H., Pearle J., Weinstein D., Galanis T. P., Gazmuri R., Kastelic R., Martinez R., Laman D., Macchiavelli A., Kmetzo J., Thurm C., Kayembe T., Chandrashekhar Y., Bassetti D., Jaoude P., Williams H., Dewhurst R., Naqvi S., Burr J., Rodriguez-Cintron W., Jeanfreau R., Kosinski E., Ndukwu I. M., Sotolongo C., Daboul N., Wilmer C., Simon P., Tak T., Rees C., Gupta N., Lerner R., Graffagnino C., Reed R. M., Alford C. M., Mody F., Wellmon B., Hamroff G., Rajan R., Kaatz S., OMÜ, Spyropoulos, A, Ageno, W, Albers, G, Elliott, C, Halperin, J, Hiatt, W, Maynard, G, Steg, P, Weitz, J, Suh, E, Spiro, T, Barnathan, E, Raskob, G, Douketis, J, Turpie, A, Schulman, S, Kearon, C, Linkins, L, Schellong, S, Bauer, K, Geerts, W, Roberts, R, Casais, P, Gallus, A, Karrasch, J, Eichinger-Hasenauer, S, Krivenchuk, V, Hadzovic-Dzuvo, A, Trbojevic, S, Lopes, R, Mincheva, V, Carrier, M, Dennis, R, Tudoric, N, Spinar, J, Nielsen, H, Marandi, T, Shaburishvili, T, Beyer-Westendorf, J, Vardas, P, Boda, Z, Brenner, B, Piovella, F, Krievins, D, Petrauskiene, B, Dejanova-Ilijevska, V, Virgen Carrillo, L, Middeldorp, S, Castillo Leon, R, Torbicki, A, Saraiva de Sousa, M, Dorobantu, M, Militaru, C, Yavelov, I, Vuckovic, B, Reuter, H, Basson, M, Monreal, M, Kucukoglu, S, Parkhomenko, A, Alikhan, R, Rosenberg, D, Yusen, R, Khorana, A, Tapson, V, Pollack, C, Hazelrigg, M, Jure, H, Alvarisqueta, A, Cartasegna, L, Hominal, M, Cursack, G, Alzogaray, M, Maillo, M, Parody, M, Caccavo, A, Dran, R, Muntaner, J, Casas, M, Schmidberg, J, Sarjanovich, R, Gabito, A, Garrido, M, Amuchastegui, M, Fernandez, A, Loureyro, J, Giumelli, C, Heazlewood, V, Colquhoun, D, White, H, Sabet, A, Bowler, S, Carroll, P, Khalafallah, A, Baker, R, Hedger, S, Simpson, F, Jackson, D, Chong, B, Siostrzonek, P, Gary, T, Hoppe, U, Dosta, N, Prystrom, A, Gorokhovsky, S, Yanushko, V, Skrahin, A, Kulik, A, Maslianski, B, Yakubtsevich, R, Timkin, I, Moguchaya, O, Tanaskovic, N, Miljkovic, S, Stojkovic, S, Kovacevic-Preradovic, T, Jovic, D, Basagic, E, Radjen, M, Mutapcic, M, Rizvanovic-Vojic, E, Galic, K, Terzic, I, Pojskic, B, Stevanovic, D, Cehajic, M, Rech, R, Annichino-Bizzacchi, J, Stelmach, R, Blanco, D, Castro, I, Backes, L, Saraiva, J, Ramacciotti, E, de Barros e Silva, P, Reis, G, Moreira Vieira, E, Leaes, P, Zimmermann, S, Van Bellen, B, Precoma, D, Luiz Silvestrini, T, Hernandes, M, Kyoleyan, M, Kalinova, T, Tiholov, R, Petrov, I, Mihov, A, Chompalova, B, Velikov, C, Pencheva, G, Atanasov, P, Raev, D, Kinova, E, Peltegov, V, Marchev, S, Siulemezova, S, Ayryanova, I, Grigorov, M, Naydenova, I, Koteva, N, Dimov, B, Runev, N, Getov, D, Metev, H, Donchev, K, Taseva, M, Hadzhieva, A, Benov, H, Stoyanov, M, Tisheva-Gospodinova, S, Mihaylova, N, Abadzhiev, S, Atzev, B, Georgiev, R, Mollov, M, Stoikov, A, Mazhdrakov, G, Karastanev, K, Dube, F, Roth, S, Mansour, S, Wu, C, Dolan, S, Pesant, Y, Pietrangelo, M, Dresser, G, Kahn, S, Kruisselbrink, R, Cadena Bonfanti, A, Botero, R, Quintero Ossa, A, Poveda, C, Cedano, J, Gomez Isaza, L, Villaquiran Torres, C, Gomez Mesa, J, Vargas Alonso, R, Espinosa, D, Rodriguez, J, Sanchez, G, Accini Mendoza, J, Gomez Florez, C, Cuervo Millan, F, Pesek, K, Horvat, D, Fuckar, K, Ruzic, A, Ostricki, B, Knezevic, A, Breitenfeld, T, Laganovic, M, Samodol, A, Sikic, J, Starcevic, B, Babic, Z, Samarzija, M, Milas, K, Votocek, S, Kvapil, M, Kolman, P, Bindas, P, Simon, V, Adamek, T, Svobodova, J, Gergely, L, Lastuvka, J, Macel, I, Navratil, K, Gregor, P, Lacnak, B, Janousek, J, Kellnerova, I, Hulinsky, V, Matusek, Z, Prucek, L, Dunaj, M, Pirchala, M, Vencour, D, Pavolko, M, Gorican, K, Fiksa, J, Tuxen, C, Meyer, C, Suppli Ulrik, C, Uuetoa, T, Otarishvili, N, Khintibidze, I, Emukhvari, N, Kipiani, Z, Gochitashvili, D, Mamatsashvili, M, Megreladze, I, Paposhvili, K, Agladze, R, Eradze, Z, Chelidze, K, Lominadze, S, Chukhrukidze, A, Chumburidze, V, Metreveli, S, Danelia, V, Orjonikidze, S, Kobulia, B, Nikolaishvili, G, Gvenetadze, R, Melia, A, Tsinamdzgvrishvili, B, Sekhniashvili, M, Sikharulidze, I, Meuser, M, Licka, M, Rauch-Kroehnert, U, Graf, K, Brachmann, J, Akin, I, Toumbis, M, Vassilikos, V, Konstantinides, S, Steiropoulos, P, Gogos, C, Andrikopoulos, G, Parthenakis, F, Karydi, P, Tsivgoulis, G, Mertzanos, G, Olympios, C, Karapanayiotides, T, Paraskevopoulou, E, Kifnidis, K, Hahalis, G, Skoutelis, A, Vadikolias, K, Nyirati, G, Nagy, L, Matoltsy, A, Komoly, S, Lippai, J, Kiss, K, Toth, K, Pozsegovits, K, Kiraly, C, Bereczki, D, Zolyomi, S, Szakal, I, Pall, D, Futo, L, Forster, T, Lovasz, O, Papp, A, Kiraly, Z, Pozsonyi, Z, Hajko, E, Kristof, P, Lakatos, F, Ples, Z, Kirschner, R, Lupkovics, G, Timar, G, Pinter, I, Kristof, T, Kis, E, Kovacs, A, Jakab, G, Palinkas, A, Muller, G, Turi, T, Horvath, C, Kondakor, I, Csanyi, A, Frankfurter, Z, Gurzo, M, Gafter-Gvili, A, Kuchuk, M, Azzam, Z, Elis, A, Halabi, M, Hussein, O, Blum, A, Tsoran-Rosenthal, I, Lishner, M, Hochberg-Klein, S, Caraco, Y, Atar, S, Elias, N, Gavish, D, Butnaru, A, Cosmi, F, Garbelotto, R, Giorgi Pierfranceschi, M, Simioni, L, Gronda, E, Pesci, A, D'Angelo, A, Fedele, F, Ghirarduzzi, A, Piovaccari, G, Lembo, G, Ria, L, Monaco, G, Brunelli, C, Tosetto, A, Capucci, A, Zanatta, N, Pistolesi, M, Mazzi, V, Testa, S, Scherillo, M, Di Biase, M, Antonicelli, R, Lodigiani, C, Nassiacos, D, Viksne, I, Lapkovska, Z, Rancane, G, Sime, I, Pontaga, N, Eglite, R, Puzule, S, Smolova, R, Butkiene, Z, Bagdonas, A, Raugaliene, R, Norkiene, S, Norviliene, R, Basijokiene, V, Stonkus, S, Griskeviciene, V, Miskiniene, A, Norvaisiene, R, Skripkauskiene, I, Jovkovska-Kaeva, B, Kochovska-Kamchevska, N, Antovski, A, Nechevska, L, Celeska, V, Ilievska-Poposka, B, Kostojchinoska, M, Donchovska, S, Kedev, S, Kuzmanovski, I, Bushletikj, O, Stojchev, S, Bakrachevski, N, Kuzmanovska, B, Angusheva, T, Llamas Esperon, G, Valdez Lopez, H, Medina Pech, C, Cortes Hernandez, M, Gans, S, Smulders, S, Swart, H, Boersma, W, Goosens, M, Hovens, M, Semplonius, G, Sohne, M, Lema Osores, J, Salas Perez, M, Rodriguez, A, Rios Oliva, C, Cotrina, R, Berrospi Argandona, P, Toce Yanez, L, Chavez Ayala, C, Mirek-Bryniarska, E, Goch, A, Skucha, W, Skorski, M, Miekus, P, Szyszka, A, Piotrowski, G, Gniot, J, Czerski, T, Debich, P, Zaluska, R, Bebenek, W, Wozakowska-Kaplon, B, Sciborski, R, Ilkowski, J, Wojnowski, P, Uscinska, E, Gaciong, Z, Bonek, R, Sobkowicz, B, Berkowski, P, Bejgier, K, Polonski, L, Kosior, D, Lata, S, Kolodziej, P, Gessek, J, Kachel, T, Talalaj, M, Musial, J, Lewczuk, J, Krysiak, W, Kucharski, L, Wysokinski, A, Minc, P, Martinez, J, Gregorio, T, Almeida, F, Monteiro, P, Stanciulescu, G, Mercea, C, Iosipescu, L, Ciobotaru, V, Crisu, D, Burca, M, Tudoran, M, Savu, A, Negrean, V, Cojocaru, C, Minescu, B, Popa, V, Blajan, D, Nastase-Melicovici, D, Fruntelata, A, Barbulescu, S, Lukinyh, L, Akhunova, S, Vishneva, E, Semenova, I, Nikolaev, K, Shaydyuk, O, Nilk, R, Shalnev, V, Apartsin, K, Goloshchekin, B, Shpagina, L, Khlevchuk, T, Arkhipov, M, Malygin, A, Shvarts, Y, Khaisheva, L, Popov, D, Kobalava, Z, Lipchenko, A, Shapovalova, Y, Zrazhevsky, K, Greshnova, I, Maslova, N, Karabenenko, A, Shogenov, Z, Budankova, E, Barbarash, O, Uspenskiy, Y, Kosmacheva, E, Berns, S, Kostenko, V, Zateyshchikov, D, Vishnevsky, A, Boldueva, S, Podzolkov, V, Sergeeva, E, Grinshtein, Y, Khrustalev, O, Bugrova, O, Repin, A, Andreev, D, Petrovic, P, Boskovic Matic, T, Apostolovic, S, Lazic, Z, Stankovic, D, Stankovic, A, Mitov, V, Sofronic, D, Kopitovic, I, Zdravkovic, V, Joksimovic, Z, Lazovic, N, Petrovic-Stanojevic, N, Ilic, A, Vujadinovic, O, Pencic-Popovic, B, Andjelkovic, N, Sekularac, N, Hinic, S, Radjen, G, Zivkovic, A, Putnikovic, B, Ivanov, I, Babic, R, Van Zyl, L, Hobson, B, Engelbrecht, J, Mitha, I, Siebert, H, Jacobson, B, Breedt, J, Prozesky, H, Ntsekhe, M, Bayat, J, Ellis, G, Tarr, G, Adler, D, Van Dyk, C, Ismail, S, Spargo, C, Abdool-Gaffar, M, Saaiman, J, Venter, K, Lorente Aroca, M, Fernandez Portales, F, Pedrajas Navas, J, Rodriguez Botaro, A, Santa Cruz Siminiani, A, Lopez Reyes, R, Bisbe i Company, J, Piedecausa Selfa, M, Velasco Garrido, J, Sobrino-Martinez, J, Munoz Delgado, G, Sala Llinas, E, Blanco Coronado, J, Almenar Bonet, L, Vida Gutierrez, M, Sanchez Lora, F, Sanchez Martinez, R, Calderon, E, Villalta Blanch, J, De la Hera Galarza, J, Bustamante Ruiz, A, Garcia-Fuster, M, Ripoll Vera, T, Alvarez-Sala Walter, L, Todoli Parra, J, Diaz Fernandez, J, Bosa Ojeda, F, Pellicer-Ciscar, C, Jara Palomares, L, Quiles Granado, J, Trigo Bautista, A, Ruiz Bustillo, S, Ordi Ros, J, Tolosa-Vilella, C, Marin Ortuno, F, Garcia Sanchez, F, Barba Martin, R, Segovia Cubero, J, Cuervas-Mons Martinez, V, Galan Montejano, M, Lopez Meseguer, M, Sener Comert, S, Koksal, N, Tertemiz, K, Ernam, D, Dursun, A, Yildiz, O, Rudenko, L, Abrahamovych, O, Goloborodko, A, Holovchenko, N, Kulyk, A, Yagensky, A, Batushkin, V, Zolotaikina, V, Kozyolkin, O, Faynyk, A, Maslovskyy, V, Petrovskyy, R, Koshlia, V, Chopey, I, Burmak, I, Malynovsky, Y, Voronkov, L, Karpenko, O, Dziublyk, O, Godlevska, O, Borovyk, V, Bezrodna, L, Serik, S, Ovsyannikova, N, Vynnychenko, L, Kopytsya, M, Rudkovskiy, V, Grishyna, O, Vyshnyvetskyy, I, Prystupa, L, Tseluyko, V, Perepeliuk, M, Koval, O, Sychov, O, Church, A, Goudie, A, Elliott, M, Ferguson, C, Welker, J, Kao, C, Bhagwat, R, Serota, H, Bozorgchami, H, Nambiar, R, Spilseth, S, Bhagwath, G, Syed, F, Morrow, L, Updegrove, J, Bercz, P, Kambo, V, Henderson, D, Wright, P, Dang, N, Nadar, V, Jaffrani, N, El-Shahawy, M, Grossman, C, Pearle, J, Weinstein, D, Galanis, T, Gazmuri, R, Kastelic, R, Martinez, R, Laman, D, Macchiavelli, A, Kmetzo, J, Thurm, C, Kayembe, T, Chandrashekhar, Y, Bassetti, D, Jaoude, P, Williams, H, Dewhurst, R, Naqvi, S, Burr, J, Rodriguez-Cintron, W, Jeanfreau, R, Kosinski, E, Ndukwu, I, Sotolongo, C, Daboul, N, Wilmer, C, Simon, P, Tak, T, Rees, C, Gupta, N, Lerner, R, Graffagnino, C, Reed, R, Alford, C, Mody, F, Wellmon, B, Hamroff, G, Rajan, R, and Kaatz, S
- Subjects
Male ,medicine.medical_specialty ,Aftercare ,Aged ,Double-Blind Method ,Drug Administration Schedule ,Factor Xa Inhibitors ,Female ,Hemorrhage ,Humans ,Kaplan-Meier Estimate ,Middle Aged ,Patient Discharge ,Rivaroxaban ,Treatment Outcome ,Venous Thromboembolism ,Venous Thrombosis ,Hospitalization ,Medicine (all) ,030204 cardiovascular system & hematology ,Placebo ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,Randomized controlled trial ,law ,Medical illness ,Internal medicine ,Hospital discharge ,Medicine ,Venous Thrombosi ,030212 general & internal medicine ,Thromboprophylaxis ,business.industry ,General Medicine ,medicine.disease ,Venous thrombosis ,Increased risk ,rivaroxaban ,thromboprophylaxis ,medical illness ,business ,Venous thromboembolism ,Factor Xa Inhibitor ,Human ,medicine.drug - Abstract
Zateyshchikov, Dmitry A/0000-0001-7065-2045; Vyshnyvetskyy, Ivan/0000-0001-7228-3052; Bustillo, Sonia Ruiz/0000-0002-6074-914X; Maslovskyi, Valentyn/0000-0001-5184-1799; Ruzic, Alen/0000-0001-5031-2975; Nikolaev, Konstantin/0000-0003-4601-6203; Musial, Jacek/0000-0002-8994-0036; Malynovsky, Yaroslav V/0000-0002-9118-1104; Tsivgoulis, Georgios/0000-0002-0640-3797; Maslovskyi, Valentyn/0000-0001-5184-1799; Grinshtein, Yury/0000-0001-8847-235X; Shpagina, Lyubov/0000-0003-0871-7551; Yildiz, Oznur/0000-0002-5379-6829; Marchev, Sotir/0000-0001-9250-510X; Weitz, Jeffrey/0000-0002-1092-7550; Apartsin, Konstantin A/0000-0003-0577-9001; Reis, Gilmar/0000-0002-4847-1034; Baker, Ross/0000-0002-2728-6788; Koziolkin, Olexandr/0000-0001-9878-5798; Barbarash, Olga/0000-0002-4642-3610; Sala-Llinas, Ernest/0000-0002-6499-1638; Gallus, Alexander/0000-0001-7347-9989; lodigiani, corrado/0000-0002-9152-9385; Kosmacheva, Elena/0000-0001-8600-0199; Ramacciotti, Eduardo/0000-0002-5735-1333; Khorana, Alok/0000-0002-9509-0998; Giorgi-Pierfranceschi, Matteo/0000-0002-7988-9652; Torbicki, Adam/0000-0003-3475-8832; Abragamovic, Orest/0000-0001-6862-6809; Jara-Palomares, Luis/0000-0002-4125-3376; Prozesky, Hans/0000-0001-9715-3449; Andreev, Denis/0000-0002-0276-7374; Cuervas-Mons Martinez, Valentin/0000-0003-3086-9463; Apostolovic, Svetlana/0000-0001-9015-297X; Gregorio, Tiago/0000-0002-0131-9430; Sanchez Martinez, Rosario/0000-0003-0408-3029; Antonicelli, Roberto/0000-0002-5921-1828; Konstantinides, Stavros/0000-0001-6359-7279; Karapanayiotides, Theodoros/0000-0002-2357-7967; Repin, Alexey/0000-0001-7123-0645 WOS: 000445020900006 PubMed: 30145946 BACKGROUND Patients who are hospitalized for medical illness remain at risk for venous thromboembolism after discharge, but the role of extended thromboprophylaxis in the treatment of such patients is a subject of controversy. METHODS In this randomized, double-blind trial, medically ill patients who were at increased risk for venous thromboembolism on the basis of a modified International Medical Prevention Registry on Venous Thromboembolism (IMPROVE) score of 4 or higher (scores range from 0 to 10, with higher scores indicating a higher risk of venous thromboembolism) or a score of 2 or 3 plus a plasma n-dimer level of more than twice the upper limit of the normal range (defined according to local laboratory criteria) were assigned at hospital discharge to either once-daily rivaroxaban at a dose of 10 mg (with the dose adjusted for renal insufficiency) or placebo for 45 days. The primary efficacy outcome was a composite of symptomatic venous thromboembolism or death due to venous thromboembolism. The principal safety outcome was major bleeding. RESULTS Of the 12,024 patients who underwent randomization, 12,019 were included in the intention-to-treat analysis. The primary efficacy outcome occurred in 50 of 6007 patients (0.83%) who were given rivaroxaban and in 66 of 6012 patients (1.10%) who were given placebo (hazard ratio, 0.76; 95% confidence interval [CI], 0.52 to 1.09; P=0.14). The prespecified secondary outcome of symptomatic nonfatal venous thromboembolism occurred in 0.18% of patients in the rivaroxaban group and 0.42% of patients in the placebo group (hazard ratio, 0.44; 95% CI, 0.22 to 0.89). Major bleeding occurred in 17 of 5982 patients (0.28%) in the rivaroxaban group and in 9 of 5980 patients (0.15%) in the placebo group (hazard ratio, 1.88; 95% CI, 0.84 to 4.23). CONCLUSIONS Rivaroxaban, given to medical patients for 45 days after hospital discharge, was not associated with a significantly lower risk of symptomatic venous thromboembolism and death due to venous thromboembolism than placebo. The incidence of major bleeding was low. Janssen Research and Development; Daiichi SankyoDaiichi Sankyo Company Limited; Portola; Boehringer IngelheimBoehringer Ingelheim; JanssenJohnson & Johnson USAJanssen Biotech Inc; BayerBayer AG; BMS PfizerPfizer; Aspen; Sanofi; University of Cincinnati and Spectrum Health; PfizerPfizer; ATLAS Group (Colorado Prevention Center); Johnson JohnsonJohnson & Johnson USA; Ortho-McNeil-JanssenJohnson & Johnson USAJanssen Biotech Inc; Bayer/JanssenJohnson & Johnson USAJanssen Biotech IncBayer AG; MerckMerck & Company; AmgenAmgen Supported by Janssen Research and Development.r Dr. Spyropoulos reports receiving advisory board fees from Daiichi Sankyo and Portola, grant support, consulting fees, and advisory board fees from Boehringer Ingelheim and Janssen, consulting fees and advisory board fees from Bayer, and a stipend from ATLAS Group (Colorado Prevention Center); Dr. Ageno, receiving grant support and advisory board fees from Bayer and BMS Pfizer and advisory board fees from Portola, Daiichi Sankyo, Aspen, Boehringer Ingelheim, and Sanofi; Dr. Albers, receiving consulting fees from Bayer; Dr. Elliott, receiving fees for serving on a steering committee from Bayer and lecture fees from the University of Cincinnati and Spectrum Health; Dr. Halperin, receiving consulting fees from Boehringer Ingelheim, Daiichi Sankyo, Pfizer, ATLAS Group (Colorado Prevention Center), Johnson & Johnson, and Ortho-McNeil-Janssen; Dr. Hiatt, receiving grant support from Janssen and Bayer; Dr. Steg, receiving grant support and fees for serving on a steering committee from Bayer/Janssen, grant support and lecture fees from Merck, grant support, consulting fees, lecture fees, and fees for serving as cochair of the ODYSSEY outcomes trial and the SCORED trial from Sanofi, grant support and fees for serving as chair of the CLARIFY registry from Servier, consulting fees and fees for serving on the executive steering committee for the REDUCE IT trial from Amarin, consulting fees and lecture fees from Amgen, consulting fees, lecture fees, and fees for critical event committee work from Bristol-Myers Squibb, fees for serving on the executive steering committee of the REDUAL PCI trial from Boehringer Ingelheim, fees for critical event committee work from Pfizer, consulting fees and fees for serving on the executive steering committee for the PARADISE MI trial from Novartis, consulting fees from Regeneron and Lilly, and consulting fees and fees for serving as cochair of the THEMIS trial from AstraZeneca; Dr. Weitz, receiving consulting fees and honoraria from Bayer, Boehringer Ingelheim, Bristol-Myers Squibb, Daiichi Sankyo, Ionis, Janssen, Merck, Novartis, Pfizer and Portola; Dr. Suh and Dr. Barnathan, being employed by Janssen Research and Development and owning stock in Johnson & Johnson; Dr. Spiro, being employed by and owning shares in Bayer U.S.; and Dr. Raskob, receiving consulting fees from Bayer, BMS, Boehringer Ingelheim, Eli Lilly, Portola, and Novartis and consulting fees and honoraria from Daiichi Sankyo and Pfizer. No other potential conflict of interest relevant to this article was reported.
- Published
- 2018
25. Association between cystatin C and major adverse cardiac events in patients with ischemic heart disease and type 2 diabetes mellitus after acute coronary syndrome
- Author
-
Serik, S. A. and Ovrakh, T. H.
- Subjects
ішемічна хвороба серця ,цукровий діабет 2 типу ,цистатин С ,cardiovascular diseases ,ишемическая болезнь сердца ,сахарный диабет 2 типа ,myocardial ischemia ,type 2 diabetes mellitus ,cystatin C - Abstract
Purpose. To evaluate the level of cystatin C and its association with the risk of developing repeated major adverse cardiac events (MACE) in patients with ischemic heart disease (IHD) and preserved kidney function in combination with type 2 diabetes mellitus (DM) within 12 months after acute coronary syndrome (ACS).Materials and methods. A total of 88 patients, aged 30–75 years, (59 patients with DM and 29 patients without DM) with prior ACS (unstable angina or myocardial infarction) in the previous 4–6 weeks were enrolled. The control group consisted of 15 healthy persons. The follow-up period was 11 months.Results. Cystatin C level in patients with DM was higher than in patients without DM (2057.69 ± 107.56 ng/ml vs 1376.57 ± 81.11 ng/ml, P < 0.05). In patients with CHD without diabetes, the level of cystatin C was although higher than in the control group, but not statistically significantly (P > 0.05).During the follow-up period, the MACE rate in DM patients was higher than in patients without DM, 40.68 % (n = 24) and 10.34 % (n = 3), respectively, P < 0.05. According to the ROC analysis, cystatin C level of more than 1942.62 ng/ml was associated with MACE occurrence in DM patients within 12 months after ACS, the sensitivity of the method was 82.60 %, specificity – 64.30 %. As a result of the multivariate regression analysis adjusted for age and sex, it has been identified that cystatin C was an independent predictor for MACE occurrence in DM patients within 12 months after ACS (OR 3ю78, 95 % CI [1.51, 7.41], P = 0.001).Conclusions. Cystatin C was an independent predictor for MACE after ACS in patients with DM and preserved kidney function., Цель работы – оценить уровень цистатина С и его связь с риском развития повторных сердечно-сосудистых событий у больных ишемической болезнью сердца (ИБС) с сохраненной функцией почек в сочетании с сахарным диабетом (СД) 2 типа в течение 12 месяцев после перенесенного острого коронарного синдрома (ОКС).Материалы и методы. В исследование включены 88 больных ИБС в возрасте от 30 до 75 лет с сохраненной функцией почек (СКФ > 60 мл/мин/1,73 м2 ), которые за 4–6 недель до включения в исследование перенесли ОКС (нестабильную стенокардию или инфаркт миокарда (ИМ)). 59 больных ИБС были с СД 2 типа, 29 пациентов без СД. Группу контроля составили 15 здоровых человек. Период наблюдения за больными составил 11 месяцев.Результаты. Уровень цистатина С в группе больных ИБС и СД 2 типа (2057,69 ± 107,56 нг/мл) был достоверно выше в сравнении с больными ИБС без СД (1376,57 ± 81,11 нг/мл) и лицами группы контроля (1236,41 ± 77,91 нг/мл) (p < 0,001). У больных ИБС без СД уровень цистатина С был выше, чем в контрольной группе, однако отличия не достоверны (р > 0,05).За период наблюдения частота возникновения повторных сердечно-сосудистых событий у больных после ОКС с СД 2 типа была достоверно выше, чем у больных без СД 2 типа (40,68 % (n = 24) и 10,34 % (n = 3) соответственно, р < 0,05).По данным ROC анализа, уровень цистатина С выше 1942,62 нг/мл ассоциировался с возникновением повторных кардиоваскулярных событий у пациентов с СД 2 типа в течение 12 месяцев после ОКС (чувствительность метода составила 82,6 %, специфичность – 64,3 %). В результате многофакторного регрессионного анализа, корригированного по возрасту и полу, установлено, что цистатин С был независимым предиктором возникновения сердечно-сосудистых событий у больных СД 2 типа в течение 12 месяцев после перенесенного ОКС (ОШ 3,78; 95 % ДИ [1,51; 7,41]; р = 0,001).Выводы. Цистатин С у больных ИБС с СД 2 типа и сохраненной функцией почек – независимый предиктор развития повторных сердечно-сосудистых событий., Мета роботи – оцінити рівень цистатину С і його зв’язок із ризиком розвитку повторних серцево-судинних подій у хворих на ішемічну хворобу серця (ІХС) зі збереженою функцією нирок у поєднанні з цукровим діабетом (ЦД) 2 типу протягом 12 місяців після перенесеного гострого коронарного синдрому (ГКС).Матеріали та методи. У дослідження залучили 88 хворих на ІХС віком від 30 до 75 років зі збереженою функцією нирок (ШКФ > 60 мл/хв/1,73 м2), які за 4–6 тижнів до включення в дослідження перенесли ГКС (нестабільну стенокардію або інфаркт міокарда (ІМ)). 59 хворих на ІХС мали ЦД 2 типу, 29 пацієнтів – без ЦД. Група контролю – 15 здорових осіб. Період спостереження за хворими становив 11 місяців.Результати. Рівень цистатину С у групі пацієнтів з ІХС і ЦД 2 типу (2057,69 ± 107,56 нг/мл) був вірогідно вищим порівняно з хворими на ІХС без ЦД (1376,57 ± 81,11 нг/мл) та особами групи контролю (1236,41 ± 77,91 нг/мл) (р < 0,001). У хворих на ІХС без ЦД рівень цистатину С був вищим, ніж у контрольній групі, але відмінності невірогідні (р > 0,05).За період спостереження частота виникнення повторних серцево-судинних подій у хворих після ГКС із ЦД 2 типу була вірогідно більшою, ніж у пацієнтів без ЦД (40,68 % (n = 24) та 10,34 % (n = 3) відповідно, р < 0,05).За даними ROC аналізу, цистатин С понад 1942,62 нг/мл асоціювався з виникненням повторних кардіоваскулярних подій у хворих на ЦД 2 типу протягом 12 місяців після ГКС (чутливість методу дорівнювала 82,6 %, специфічність – 64,3 %). У результаті багатофакторного регресійного аналізу, корегованого за віком і статтю, встановили, що цистатин С – незалежний предиктор виникнення серцево-судинних подій у хворих на ЦД 2 типу протягом 12 місяців після перенесеного ГКС (ВШ 3,78; 95 % ДІ [1,51; 7,41], р = 0,001).Висновки. Цистатин С у хворих на ІХС із ЦД 2 типу і збереженою функцією нирок є незалежним предиктором розвитку повторних серцево-судинних подій.
- Published
- 2019
26. Management of dyslipidaemia in patients with coronary heart disease: Results from the ESC-EORP EUROASPIRE V survey in 27 countries
- Author
-
De Backer, Guy Jankowski, Piotr Kotseva, Kornelia and Mirrakhimov, Erkin Reiner, Zeljko Ryden, Lars Tokgozoglu, Lale Wood, David De Bacquer, Dirk Abreu, A. Aguiar, C. and Badariene, J. Bruthans, J. Castro Conde, A. Cifkova, R. and Crowley, J. Davletov, K. De Smedt, D. De Sutter, J. and Deckers, J. W. Dilic, M. Dolzhenko, M. Druais, H. and Dzerve, V. Erglis, A. Fras, Z. Gaita, D. Gotcheva, N. and Grobbee, D. E. Gyberg, V. Ali, H. Hasan Heuschmann, P. and Hoes, A. W. Lalic, N. Lehto, S. Lovic, D. Maggioni, A. P. Mancas, S. Marques-Vidal, P. Mellbin, L. Milicic, D. Oganov, R. Pogosova, N. Stagmo, M. Stoerk, S. and Sundvall, J. Tsioufis, K. Vulic, D. Wood, D. A. and Jennings, C. Adamska, A. Adamska, S. Mellbin, L. and Tuomilehto, J. Schnell, O. Fiorucci, E. Glemot, M. and Larras, F. Missiamenou, V. Maggioni, A. Taylor, C. and Ferreira, T. Lemaitre, K. Raman, L. Sundvall, J. and DeSmedt, D. De Sutter, J. Willems, A. M. De Pauw, M. and Vervaet, P. Bollen, J. Dekimpe, E. Mommen, N. Van Genechten, G. Dendale, P. Bouvier, C. A. Chenu, P. and Huyberechts, D. Persu, A. Dilic, M. Begic, A. Nalbantic, A. Durak Dzubur, A. Hadzibegic, N. Iglica, A. Kapidjic, S. Bico, A. Osmanagic Resic, N. Bajramovic, N. Sabanovic and Zvizdic, F. Vulic, D. Kovacevic-Preradovic, T. and Popovic-Pejicic, S. Djekic, D. Gnjatic, T. Knezevic, T. and Kovacevic-Preradovic, T. Kos, Lj Popovic-Pejicic, S. and Stanetic, B. Topic, G. Gotcheva, N. Georgiev, Borislav and Terziev, A. Vladimirov, G. Angelov, A. Kanazirev, B. and Nikolaeva, S. Tonkova, D. Vetkova, M. Milicic, D. and Bosnic, A. Dubravcic, M. Glavina, M. Mance, M. and Pavasovic, S. Samardzic, J. Batinic, T. Crljenko, K. and Delic-Brkljacic, D. Dula, K. Golubic, K. Klobucar, I. and Kordic, K. Kos, N. Nedic, M. Olujic, D. Sedinic, V. and Blazevic, T. Pasalic, A. Percic, M. Sikic, J. Bruthans, J. Cifkova, R. Hasplova, K. Sulc, P. Wohlfahrt, P. and Mayer, Jr., O. Cvicela, M. Filipovsky, J. Gelzinsky, J. and Hronova, M. Hasan-Ali, H. Bakery, S. Mosad, E. Hamed, H. B. Ibrahim, A. Elsharef, M. A. Kholef, E. F. Shehata, A. and Youssef, M. Elhefny, E. Farid, H. Moustafa, T. M. and Sobieh, M. S. Kabil, H. Abdelmordy, A. Lehto, S. and Kiljander, E. Kiljander, P. Koukkunen, H. Mustonen, J. and Cremer, C. Frantz, S. Haupt, A. Hofmann, U. Ludwig, K. and Melnyk, H. Noutsias, M. Karmann, W. Prondzinsky, R. and Herdeg, C. Hoevelborn, T. Daaboul, A. Geisler, T. and Keller, T. Sauerbrunn, D. Walz-Ayed, M. Ertl, G. Leyh, R. Stoerk, S. Heuschmann, P. Ehlert, T. Klocke, B. and Krapp, J. Ludwig, T. Kaes, J. Starke, C. Ungethuem, K. and Wagner, M. Wiedmann, S. Tsioufis, K. Tolis, P. and Vogiatzi, G. Sanidas, E. Tsakalis, K. Kanakakis, J. and Koutsoukis, A. Vasileiadis, K. Zarifis, J. Karvounis, C. and Crowley, J. Gibson, I. Houlihan, A. Kelly, C. O'Donnell, M. Bennati, M. Cosmi, F. Mariottoni, B. Morganti, M. and Cherubini, A. Di Lenarda, A. Radini, D. Ramani, F. and Francese, M. G. Gulizia, M. M. Pericone, D. Davletov, K. and Aigerim, K. Bekbolat, Z. Amirov, B. Assembekov, B. and Chernokurova, E. Ibragimova, F. Kodasbayev, A. Markova, A. and Asanbaev, A. Toktomamatov, U. Tursunbaev, M. Zakirov, U. and Abilova, S. Arapova, R. Bektasheva, E. Esenbekova, J. and Neronova, K. Asanbaev, A. Baigaziev, K. Toktomamatov, U. and Zakirov, U. Baitova, G. Zheenbekov, T. Erglis, A. and Andrejeva, T. Bajare, I. Kucika, G. Labuce, A. Putane, L. Stabulniece, M. Dzerve, V. Klavins, E. Sime, I. and Badariene, J. Gedvilaite, L. Peciuraite, D. Sileikiene, V. and Skiauteryte, E. Solovjova, S. Sidabraite, R. Briedis, K. and Ceponiene, I. Jurenas, M. Kersulis, J. Martinkute, G. and Vaitiekiene, A. Vasiljevaite, K. Veisaite, R. Plisiene, J. Siurkaite, V. Vaiciulis, Z. Czarnecka, D. Koziel, P. and Podolec, P. Nessler, J. Gomula, P. Mirek-Bryniarska, E. and Bogacki, P. Wisniewski, A. Pajak, A. Wolfshaut-Wolak, R. and Bucko, J. Kaminski, K. Lapinska, M. Paniczko, M. and Raczkowski, A. Sawicka, E. Stachurska, Z. Szpakowicz, M. and Musial, W. Dobrzycki, S. Bychowski, J. Kosior, D. A. and Krzykwa, A. Setny, M. Kosior, D. A. Rak, A. Gasior, Z. and Haberka, M. Gasior, Z. Haberka, M. Szostak-Janiak, K. and Finik, M. Liszka, J. Botelho, A. Cachulo, M. Sousa, J. Pais, A. Aguiar, C. Durazzo, A. Matos, D. and Gouveia, R. Rodrigues, G. Strong, C. Guerreiro, R. and Aguiar, J. Abreu, A. Cruz, M. Daniel, P. Morais, L. and Moreira, R. Rosa, S. Rodrigues, I. Selas, M. Gaita, D. and Mancas, S. Apostu, A. Cosor, O. Gaita, L. Giurgiu, L. Hudrea, C. Maximov, D. Moldovan, B. Mosteoru, S. and Pleava, R. Ionescu, M. Parepa, I. Pogosova, N. and Arutyunov, A. Ausheva, A. Isakova, S. Karpova, A. and Salbieva, A. Sokolova, O. Vasilevsky, A. Pozdnyakov, Y. and Antropova, O. Borisova, L. Osipova, I. Lovic, D. and Aleksic, M. Crnokrak, B. Djokic, J. Hinic, S. Vukasin, T. Zdravkovic, M. Lalic, N. M. Jotic, A. Lalic, K. and Lukic, L. Milicic, T. Macesic, M. Gajovic, J. Stanarcic and Stoiljkovic, M. Djordjevic, D. Kostic, S. Tasic, I. and Vukovic, A. Fras, Z. Jug, B. Juhant, A. Krt, A. and Kugonjic, U. Chipayo Gonzales, D. Gomez Barrado, J. J. and Kounka, Z. Marcos Gomez, G. Mogollon Jimenez, M. V. Ortiz Cortes, C. Perez Espejo, P. Porras Ramos, Y. Colman, R. and Delgado, J. Otero, E. Perez, A. Fernandez-Olmo, M. R. and Torres-LLergo, J. Vasco, C. Barrenada, E. Botas, J. and Campuzano, R. Gonzalez, Y. Rodrigo, M. de Pablo, C. and Velasco, E. Hernandez, S. Lozano, C. Gonzalez, P. and Castro, A. Dalmau, R. Hernandez, D. Irazusta, F. J. and Velez, A. Vindel, C. Gomez-Doblas, J. J. Garcia Ruiz, V. and Gomez, L. Gomez Garcia, M. Jimenez-Navarro, M. Molina Ramos, A. Marzal, D. Martinez, G. Lavado, R. Vidal, A. and Bostrom-Nilsson, V. Kjellstrom, B. Shahim, B. Smetana, S. and Hansen, O. Stensgaard-Nake, E. Deckers, J. W. Klijn, A. J. Mangus, T. J. P. Peters, R. J. G. Reimer, W. Scholte Op and Snaterse, M. Aydogdu, S. Erol, C. Oturk, S. Kaya, C. Tulunay Ahmetoglu, Y. Ergene, O. Akdeniz, B. Cirgamis, D. Kultursay, S. Akkoyun H. Kayikcioglu, M. Catakoglu, A. B. and Cengel, A. Kocak, A. A. Agirbasli, M. A. Aciksari, G. and Cekin, M. E. Kaya, E. B. Kocyigit, D. Ongen, Z. and Ozmen, E. Sansoy, V. Kaya, A. Oktay, V. Temizhan, A. and Unal, S. Yakut, I. Kalkan, A. K. Bozkurt, E. Kasapkara, H. A. Dolzhenko, M. Faradzh, C. Hrubyak, L. Konoplianyk, L. Kozhuharyova, N. Lobach, L. Nesukai, V. Nudchenko, O. and Simagina, T. Yakovenko, L. Azarenko, V. Potabashny, V. and Bazylevych, A. Bazylevych, M. Kaminska, K. Panchenko, L. and Shershnyova, O. Ovrakh, T. Serik, S. Kolesnik, T. and Kosova, H. Adamska, A. Adamska, S. Jennings, C. Atkin, A. Hoye P. Fellowes, D. Lindsay, S. Atkinson, C. and Kranilla, C. Vinod, M. Beerachee, Y. Bennett, C. Broome, M. Bwalya, A. Caygill, Lindsay Dinning, L. Gillespie, A. and Goodfellow, R. Guy, J. Idress, T. Mills, C. Morgan, C. Oustance, N. Singh, N. Yare, M. Jagoda, J. M. and Bowyer, H. Christenssen, V. Groves, A. Jan, A. Riaz, A. and Gill, M. Sewell, T. A. Gorog, D. Baker, M. De Sousa, P. Mazenenga, T. Porter, J. Haines, F. Peachey, T. and Taaffe, J. Wells, K. Ripley, D. P. Forward, H. McKie, H. and Pick, S. L. Thomas, H. E. Batin, P. D. Exley, D. and Rank, T. Wright, J. Kardos, A. Sutherland, S. -B. Wren, L. Leeson, P. Barker, D. Moreby, B. Sawyer, J. and Stirrup, J. Brunton, M. Brodison, A. Craig, J. Peters, S. Kaprielian, R. Bucaj, A. Mahay, K. Oblak, M. and Gale, C. Pye, M. McGill, Y. Redfearn, H. Fearnley, M. and EUROASPIRE V Collaborators Writing Comm Sci Steering Executive Comm Coordinating Ctr Diabet Ctr Data Management Ctr Stat Anal Ctr Cent Lab Study Ctr Org Investigators Other
- Abstract
Background and aims: One of the objectives of the ESC-EORP EUROASPIRE V survey is to determine how well European guidelines on the management of dyslipidaemias are implemented in coronary patients. Methods: Standardized methods were used by trained technicians to collect information on 7824 patients from 130 centers in 27 countries, from the medical records and at a visit at least 6 months after hospitalization for a coronary event. All lipid measurements were performed in one central laboratory. Patients were divided into three groups: on high-intensity LDL-C-lowering-drug therapy (LLT), on low or moderate-intensity LLT and on no LLT. Results: At the time of the visit, almost half of the patients were on a high-intensity LLT. Between hospital discharge and the visit, LLT had been reduced in intensity or interrupted in 20.8% of the patients and had been started or increased in intensity in 11.7%. In those who had interrupted LLT or had reduced the intensity, intolerance to LLT and the advice of their physician were reported as the reason why in 15.8 and 36.8% of the cases, respectively. LDL-C control was better in those on a high-intensity LLT compared to those on low or moderate intensity LLT. LDL-C control was better in men than women and in patients with self-reported diabetes. Conclusions: The results of the EUROASPIRE V survey show that most coronary patients have a less than optimal management of LDL-C. More professional strategies are needed, aiming at lifestyle changes and LLT adapted to the need of the individual patient.
- Published
- 2019
27. Possibilities of Alfalfa Cultivation Intensification and Biologization
- Author
-
Nurlan B. Ussipbayev and Serik S. Sadvakassov
- Subjects
Drug Discovery ,Agronomy and Crop Science ,Biotechnology - Published
- 2016
28. Edoxaban versus warfarin in patients with atrial fibrillation
- Author
-
Robert P. Giugliano, Christian T. Ruff, Eugene Braunwald, Sabina A. Murphy, Stephen D. Wiviott, Jonathan L. Halperin, Albert L. Waldo, Michael D. Ezekowitz, Jeffrey I. Weitz, Jind?ich ?pinar, Witold Ruzyllo, Mikhail Ruda, Yukihiro Koretsune, Joshua Betcher, Minggao Shi, Laura T. Grip, Shirali P. Patel, Indravadan Patel, James J. Hanyok, Michele Mercuri, Elliott M. Antman, Braunwald E, Antman EM, Giugliano RP, Ruff CT, Morin SE, Hoffman EB, Murphy SA, Deenadayalu N, Grip L, Mercuri M, Lanz H, Patel I, Curt V, Duggal A, Hanyok J, Davé J, Morgan D, Choi Y, Shi M, Jin J, Xie J, Crerand W, Kappelhof J, Maxwell W, Skinner M, Patel S, Betcher J, Selicato G, Otto C. Jr, Reissner C, Smith K, Ostroske J, Ron A, Giugliano R, Connolly S, Camm J, Ezekowitz M, Halperin J, Waldo A, Paolasso E, Aylward P, Heidbuchel H, Nicolau JC, Goudev A, Roy D, Weitz J, Corbalán R, Yang Y, Botero R, Bergovec M, Ŝpinar J, Grande P, Hassager C, Voitk J, Huikuri H, Nieminen M, Blanc JJ, LeHeuzey JY, Mitrovic V, Alexopoulos D, Sotomora G, Kiss R, SomaRaju B, Lewis B, Merlini P, Metra M, Koretsune Y, Yamashita T, García Castillo A, Ophuis T, White H, Atar D, Horna M, Babilonia N, Ruzyllo W, Morais J, Dorobantu M, Ruda M, Ostojic M, Duris T, Dalby A, Chung N, Zamorano JL, Juul Möller S, Moccetti T, Chen SA, Sritara P, Oto A, Parkhomenko A, Senior R, Verheugt F, Skene A, Anderson J, Bauer K, Easton JD, Goto S, Wiviott S, Lowe C, Awtry E, Berger CJ, Croce K, Desai A, Gelfand E, Goessling W, Greenberger NJ, Ho C, Leeman DE, Link MS, Norden AD, Pande A, Rost N, Ruberg F, Silverman S, Singhal A, Vita JA, Vogelmann O, Gonzalez C, Ahuad Guerrero R, Rodriguez M, Albisu J, Rosales E, Allall O, Reguero M, Alvarez C, Garcia M, Ameriso S, Ameriso P, Amuchastegui M, Caceres M, Beloscar J, Petrucci J, Berli M, Budassi N, Valle M, Bustamante Labarta G, Saravia M, Caccavo A, Fracaro V, Cartasegna L, Novas V, Caruso O, Zarandon RS, Colombo H, Morandini M, Cuello J, Rosell M, Cuneo C, Bocanera M, D'Amico A, Cendali G, Dran R, Moreno V, Estol C, Davolos M, Facello A, Facello M, Falu E, Iriarte M, Femenia F, Arrieta M, Fuselli J, Zanotti A, Gant Lopez J, Meiller F, Garcia Duran R, Perlo D, Garrido M, Ceirano C, Giacomi G, Eden M, Giannaula R, Huerta M, Goicoechea R, von Wulffen M, Hominal M, Bianchini M, Jure H, Jure D, Kevorkian R, Monaco F, Lanternier G, Belcuore M, Liniado G, Iglesias M, Litvak B, Nigro A, Llanos J, Vignau S, Lorente C, Shatsky K, Lotti J, Raimondi G, Mackinnon I, Carne M, Manuale O, Calderon M, Marino J, Funes I, Muntaner J, Gandur H, Nul D, Verdini E, Piskorz D, Tommasi A, Povedano G, Casares E, Pozzer D, Fernandez E, Prado A, Venturini C, Ramos H, Navarrete S, Alvarez M, Sanchez A, Bowen L, Sanjurjo M, Codutti O, Saravia Toledo S, Formoso I, Schmidberg J, Goloboulicz A, Schygiel P, Buzzetti C, Severino P, Morara P, Sosa Liprandi M, Teves M, Vico M, Morell Y, Anderson C, Paraskevaidis T, Arstall M, Hoffmann B, Colquhoun D, Price Smith S, Crimmins D, Slattery A, Dart A, Kay S, Davis S, Silver G, Flecknoe Brown S, Roberts J, Gates P, Jones S, Lehman R, Morrison H, McKeirnan M, Li J, Paul V, Batta C, Purnell P, Perrett L, Szto G, O'Shea V, Capiau L, Banaeian F, De Bleecker J, de Koning K, De Tollenaere M, De Bruyne L, Desfontaines P, Tincani G, Meeusen K, Herzet J, Malmendier D, Mairesse G, Raepers M, Parqué J, Clinckemaille N, Scavée C, Huyberechts D, Stockman D, Jacobs C, Vandekerckhove Y, Derycker K, Vanwelden J, van Welden J, Vervoort G, Mestdagh I, Vrolix M, Beerts C, Wollaert B, Denie D, Amato Vincenzo de Paola A, Coutinho E, Andrade Lotufo P, de Melo RF, Atie J, Motta C, Augusto Alves da Costa F, Ferraz RF, Bertolim Precoma D, Sehnem E, Botelho R, Cunha S, Brondani R, Fleck N, Chaves Junior H, Silva J, Costantini C, Barroso D, De Patta M, Pereira V, Duda N, Laimer R, Dutra O, Morgado S, Faustino Saporito W, Seroqui M, Ferreira L, Araújo E, Finimundi H, Daitz C, Gagliardi R, Pereira G, Gomes M, Gomes A, Guimarães A, Ninho L, Jaeger C, Pereira L, Jorge J, Cury C, Kaiser S, Almeida A, Kalil C, Radaelli G, Kunz Sebba Barroso de Souza W, Morales K, Leaes P, Luiz RO, Pimenta Almeida J, Gozalo A, Reis G, Avellar K, Reis Katz Weiand L, Leipelt J, Rocha J, Barros R, Rodrigues L, Rocha MR, Rodrigues A, Rodrigues D, Rossi dos Santos F, Pagnan LG, Sampaio R, do Val R, Saraiva J, Vicente C, Simoes M, Carraro A, Sobral Filho D, Lustosa E, Villas Boas F, Almeida M, Zimmermann S, Zimmermann EB, Chompalova B, Parishev G, Denchev S, Milcheva N, Donova T, Gergova V, Georgiev B, Kostova E, Kinova E, Hergeldjieva V, Kamenova P, Manolova A, Vasilev I, Mihov A, Miteva B, Mincheva V, Stoyanovski V, Nikolov F, Vasilev D, Pencheva G, Kostov K, Petranov S, Milusheva T, Popov A, Staneva A, Momchilova Lozeva D, Todorov G, Nyagina M, Tumbev H, Tumbeva D, Tzekova M, Kitova M, Manoylov E, Archibald J, Antle S, Bhargava R, Stafford C, Bose S, Hundseth M, Cha J, Otis J, Chehayeb R, Lepage C, Chilvers M, Vansickle L, Cleveland D, Valley S, Constance C, Gauthier M, Costi P, Masson C, Coutu B, Denis I, du Preez M, Kubanska A, Dufresne M, Krider J, Eikelboom J, Zondag M, Fortin C, Viau C, Green M, Houbraken D, Hatheway R, Mabee J, Heath J, Scott L, Ho K, Ho V, Hoag G, Standring R, Huynh T, Perkins L, Kouz S, Roy M, Labonte R, Dewar C, Lainesse A, St Germain L, Lam S, Lam H, Lichtenstein T, Roberts P, Luton R, Douglas S, Ma P, Seib M, MacCallum C, Matthews J, Malette P, Vaillancourt T, Maranda C, Studenikow E, Mawji A, Morely A, Morrison D, Roth M, Mucha M, Najarali A, Lamoureux U, Nicholson R, O'Hara G, Banville P, O'Mahony W, Bolton R, Parkash R, Carroll L, Pesant Y, Sardin V, Polasek P, Turri L, Qureshi A, Nethercott C, Ricci J, Bozek B, Rupka D, Marchand C, Shu D, Silverio G, St Hilaire R, Morissette A, Sussman J, Kailey P, Syan G, Bobbie C, Talajic M, David D, Talbot P, Tremblay M, Teitelbaum I, Teitelbaum J, Velthuysen G, Giesbrecht L, Wahby R, Morley A, Wharton S, Caterini T, Woodford T, Balboa W, Matus LR, Bugueño C, Mondaca PM, Cobos J, Obreque C, Corbalan R, Parada A, Florenzano F, Diaz PA, Lopetegui M, Rebolledo C, Manriquez L, Silva LM, Martinez D, Llamas RR, Opazo M, Pérez MC, Pincetti C, Carrasco GT, Potthoff S, Staub JZ, Campisto Y, Stockins B, Lara CL, Yovaniniz P, Azua MG, Bai F, Xu GL, Chen JZ, Xie XD, Chen XP, Zhang X, Dong YG, Feng C, Fu GS, Zhang P, Hong K, You ZG, Hong L, Qiu Y, Jiang XJ, Qu Z, Li L, Liu H, Li TF, Kong YQ, Li WM, Liu B, Li ZQ, Liu Y, Liao DN, Gu XJ, Liu L, Lu ZH, Ma SM, Yang ZY, Wang DM, Qi SY, Wang GP, Shi XJ, Wei M, Huang D, Wu SL, Li YE, Xu JH, Gu JY, Xu YM, Liang YZ, Yang K, Li AY, Yang YJ, Zheng X, Zheng Y, Gao M, Yin YH, Xu YP, Yu B, Li LL, Yuan ZY, Qiang H, Zhang HQ, Lin YN, Zhang Z, Kang H, Zhao RP, Han RJ, Zhao XL, Wang JQ, Zheng ZQ, Li BG, Zhou SX, Zhang YL, Accini J, Accini M, Cano N, Pineda LL, Delgado Restrepo J, Arroyave C, Fernández Ruiz R, Diaz IA, Hernandez H, Delgado P, Jaramillo Muñoz C, Builes A, Manzur F, Rodriguez ER, Moncada Corredor M, Giraldo DL, Orozco Linares L, Fonseca J, Quintero A, Gonzales C, Sanchez Vallejo G, Mejia IP, Bagatin J, Carevic V, Car S, Jeric M, Ciglenecki N, Tusek S, Ferri Certic J, Romic I, Francetic I, Ausperger KM, Jelic V, Jurinjak SJ, Knezevic A, Buksa B, Samardzic P, Lukenda KC, Steiner R, Kirner D, Sutalo K, Bakliza Z, Vrazic H, Lucijanic T, Bar M, Brodova P, Berka L, Kunkelova V, Brtko M, Burianova H, Cermak O, Elbl L, Ferkl R, Florian J, Francek L, Golan L, Gregor P, Honkova M, Hubac J, Jandik J, Jarkovsky P, Jelinek Z, Jerabek O, Jirmar R, Kobza R, Kochrt M, Kostkova G, Kosek Z, Kovar P, Kuchar R, Kvasnicka J, Ludka O, Machova V, Krocova E, Melichar M, Nechanicky R, Olsr J, Peterka K, Petrova I, Havlova I, Pisova J, Podrazil P, Jirsova E, Reichert P, Slaby J, Spacek R, Spinar J, Labrova R, Vodnansky P, Samkova D, Zidkova E, Dodt K, Christensen H, Christensen L, Loof A, Ibsen H, Madsen H, Iversen H, Veng Olsen T, Nielsen H, Olsen R, Overgaard K, Petrovic V, Raymond I, Raae D, Sand N, Svenningsen A, Torp Pedersen C, Jakobsen U, Wiggers H, Serup Hansen K, Kaik J, Stern A, Kolk R, Laane E, Rivis L, Paumets M, Laheäär M, Rosenthal A, Rajasalu R, Vahula V, Ratnik E, Kaarleenkaski S, Hussi E, Valpas S, Jäkälä P, Lappalainen T, Mäenpää A, Viitaniemi J, Nyman K, Sankari T, Rasi H, Salminen O, Virtanen V, Nappila H, Le Heuzey J, Agraou B, El Jarroudi F, Amarenco P, Boursin P, Babuty D, Boyer M, Belhassane A, Berbari H, Blanc J, Dias P, Coisne D, Berger N, Decoulx E, El Jarroudi M, Dinanian S, Arfaoui M, Hermida J, Deruche E, Kacet S, Corbut S, Poulard J, Leparree S, Roudaut R, Duprat C, Al Zoebi A, Wurow A, Bernhardt P, Dichristin U, Berrouschot J, Vierbeck S, Beyer Westendorf J, Sehr B, Bouzo M, Schnelzer P, Braun R, Ladenburger K, Buhr M, Weihrauch D, Contzen C, Kara M, Daut W, Ayasse D, Degtyareva E, Kranz P, Drescher T, Herfurth B, Faghih M, Forck Boedeker K, Schneider K, Fuchs R, Manuela W, Grigat C, Otto A, Hartmann A, Peitz M, Heuer H, Dieckheuer U, Hoffmann U, Dorn S, Hoffmann S, Schuppe M, Horacek T, Fink P, Junggeburth J, Schmid S, Jungmair W, Schoen B, Kleinecke Pohl U, Meusel P, Koenig H, Bauch F, Lohrbaecher Kozak I, Grosse B, Lueders S, Venneklaas U, Luttermann M, Wulf M, Maus O, Hoefer K, Meissner G, Braemer U, Meyer Pannwitt U, Frahm E, Vogt S, Muegge A, Barbera S, Mueller Glamann M, Raddatz K, Piechatzek R, Lewinsky D, Pohl W, Proskynitopoulos N, Kuhlmann M, Rack K, Pilipenko H, Rinke A, Kühlenborg A, Schaefer A, Szymanowski N, Schellong S, Frommhold R, Schenkenberger I, Finsterbusch T, Dreykluft K, Schiewe C, Schmidt A, Schmidt M, Schreckenberg A, Hellmers J, Seibert H, Gold G, Sohn H, Baylacher M, Spitzer S, Bonin K, Stoehring R, Taggeselle J, Zarpentin C, Veltkamp R, Ludwig I, Voehringer, Buchholz M, Weyland K, Winkelmann B, Buelow Johansen B, Wolde C, Winter K, Mavronasiou E, Bourlios P, Tziortziotis A, Karamitsos C, Exarchou E, Kifnidis K, Daskalaki A, Moschos N, Dimitra K, Olympios C, Kartsagkoulis E, Pyrgakis V, Korantanis K, Ayau Milla O, Ramirez Vde L, Guzman Melgar I, Jimenez T, Ovando Lavagnino A, Guevara S, Rodas Estrada M, Sanchez M, Pozuelos JM, Sanchez Samayoa C, Guerra L, Velasquez Camas L, Almaraz SP, Dioszeghy P, Muskoczki E, Edes I, Szatmari J, Fiok J, Varga A, Kanakaridisz N, Kosztyu M, Kis E, Feil JF, Jakal A, Koczka M, Kovacs I, Baranyai M, Kovacs Z, Lupkovics G, Karakai HH, Matoltsy A, Kiss T, Medvegy M, Kiss K, Merkely B, Kolumban E, Nagy A, Palinkas A, Toth SR, Sayour A, Bognar A, Simor T, Ruzsa D, Sipos T, Szakal I, Tomcsanyi J, Marosi A, Vertes A, Kincses M, Malhan S, Abdullakutty J, Agarwal D, Ranka R, Arneja J, Memon A, Arora V, Shree R, Avvaru G, Shaikh A, Babu P, Rao B, Babu R, Reddy J, Banker D, Sheth T, Benjarge P, Surushe S, Bharani A, Solanki R, Bhargava V, Rathi A, Biniwale A, Bhuti M, Calambur N, Somaraju B, Karnwal N, Chopda M, Mali N, Goyal N, Saini A, Gupta J, Singh P, Hadan S, Savanth P, Hardas S, Thakor G, Hiremath J, Ghume A, Jain R, Pahuja M, Joseph S, Oommen D, Joseph J, Thomas R, Joshi H, Iby, Kale V, Raut N, Kandekar B, Kandekar S, Kishore R, Krishnan H, Kotiwale V, Kulkarni R, Deokar M, Kulkarni G, Lawande A, Kumar P, Karpuram M, Kumar A, Francis J, Kumbla M, Anthony A, Lavhe P, Kale M, Mardikar H, Bhaskarwar P, Mathur A, Sharma P, Menon J, Francis V, Namjoshi D, Shelke S, Narendra J, Natarajan S, Oomaan A, Gurusamy P, Angel J, Purayil MP, Shams S, Pandurangi U, Sababathi R, Parekh P, Jasani B, Patki N, Babbar A, Pinto B, Kharalkar H, Premchand R, Jambula H, Rao M, Vuriya A, Ravi Shankar A, Reddy R, Bekal S, Barai A, Saha D, Gadepalli R, Sant H, Jadhav D, Sarna M, Arora T, Sawhney J, Singh R, Sethi K, Bansal N, Sethia A, Sethia S, Shetty G, Sudheer R, Singh G, Gupta R, Srinivas A, Thankaraj L, Varma S, Kaur A, Vinod MV, Thakur B, Zanwar I, Dharmarao A, Atar S, Lasri E, Dicker D, Marcoviciu D, Elias M, Ron GA, Francis A, Ghantous R, Goldhaber A, Goldhaber M, Gottlieb S, Rouwaida S, Grossman E, Dagan T, Hasin Y, Roshrosh M, Hayek T, Majdoub A, Klainman E, Genin I, Lahav M, Gilat T, Ben Ari M, Lishner M, Karny M, Ouzan E, Givoni H, Rozenman Y, Logvinenko S, Schiff E, Sterlin J, Shochat M, Aloni I, Swissa M, Belatsky V, Tsalihin D, Kisos D, Zeltser D, Platner N, Berni A, Giovannelli F, Boriani G, Cervi E, Comi G, Peruzzotti L, Cuccia C, Forgione C, De Caterina R, De Pace D, De Servi S, Mariani M, Di Lenarda A, Mazzone C, Di Pasquale G, Di Niro M, Fattore L, Bosco B, Grassia V, Murena E, Laffi, Gaggioli G, Lo Pinto G, Raggi F, Marino P, Francalacci G, Babbolin M, Bulgari M, Penco M, Lioy E, Marciano C, Pirelli S, Paradiso G, Piseddu G, Fenu L, Raisaro A, Granzow K, Rasura M, Cannoni S, Severi S, Breschi M, Toschi V, Gagliano M, Zacà V, Furiozzi F, Hirahara T, Akihisa U, Masaki W, Ajioka M, Matsushita C, Anzai T, Mino K, Arakawa S, Tsukimine A, Endo H, Fujiwara M, Fujii K, Kozeni S, Fujii E, Kotera M, Fujimoto S, Omae K, Fujimoto K, Ichishita Y, Fujita T, Ito Y, Fukamizu S, Harada J, Fukuda N, Fujimoto C, Funazaki T, Yamaguchi A, Furukawa Y, Kamitake C, Hagiwara N, Naganuma M, Hara S, Kumagai S, Harada K, Fuki Y, Haruna T, Nakahara Y, Hashimoto Y, Shimazu Y, Hiasa Y, Oga Y, Higashikata T, Nakagawa Y, Hirayama A, Kawaguchi A, Iesaka Y, Miyamoto C, Iijima T, Higuchi K, Ino H, Noguchi H, Inomata T, Nakamura K, Ishibashi Y, Nozaki T, Ishii Y, Tomita H, Ishimaru S, Ise M, Itamoto K, Ito T, Onishi M, Iwade K, Sakuma Y, Iwasaki T, Nagatome H, Kakinoki S, Adachi C, Kamakura S, Nakahara F, Kamijo M, Iida S, Kamiyama K, Fujii R, Kato K, Ishida A, Kazatani Y, Ichikawa Y, Kitazawa H, Igarashi C, Kobayashi Y, Kikuchi R, Kohno M, Tamura S, Yumoto I, Kurabayashi M, Koya E, Masuyama T, Kaneno Y, Matsuda K, Ebina E, Meno H, Satake M, Mita T, Takeda M, Miyamoto N, Kimizu T, Miyauchi Y, Sakamoto S, Munemasa M, Murata J, Nagai Y, Sakata Y, Naito S, Oyama H, Nishi Y, Nagase T, Ochiai J, Junko H, Ogawa T, Sugeno M, Oguro H, Tanabe M, Okada K, Moriyama Y, Okajima K, Nakashima M, Okazaki O, Wada H, Okishige K, Kitani S, Okumura K, Narita Y, Onaka H, Moriyama H, Ozaki Y, Tanikawa I, Sakagami S, Nakano A, Sakuragi S, Hayashi N, Sakurai S, Ooki H, Sasaki T, Oosawa N, Satoh A, Fujimoto E, Seino Y, Narumi M, Shirai T, Shigenari M, Shoji Y, Ueda J, Sugi K, Miyazaki E, Sumii K, Asakura H, Takagi M, Mohri S, Takahashi W, Yoshida K, Takahashi A, Kishi N, Takahashi T, Sakurai Y, Takeda K, Yahata A, Takenaka T, Yamagishi K, Takeuchi S, Watanabe E, Tanaka K, Uchida M, Tanouchi J, Nishiya Y, Tsuboi H, Tsuboi N, Terakura K, Uematsu M, Yasumoto S, Ueyama Y, Usuda K, Sakai Y, Yagi M, Sato A, Yagi H, Kuroda T, Yamabe H, Sakamoto Y, Yamada T, Yamano R, Yamagishi T, Sasaki S, Yamamoto Y, Yamashina A, Takiguchi M, Yonehara T, Yoshino H, Nomura H, Yoshioka K, Fujiwara Y, Bayram Llamas E, Hurtado A, Calvo Vargas C, Limon MC, Cardona Muñoz E, Hernandez S, Carrillo J, Delgadillo T, Cásares Ramirez M, Valles JF, Garcia N, Colin MA, Garcia Castillo A, Jaramillo A, Leiva Pons J, de la Mora S, Llamas Esperón G, Grajales A, Mendez Machado G, Avila H, Ruiz LN, Magallanes G, Sánchez Díaz C, Ortiz A, Sánchez RV, Velazquez EM, Alhakim M, van Welsen I, Bruning T, Jones A, Buiks C, de Groot J, Radder I, de Vos R, Hazeleger R, Daniels R, Kietselaer B, Muijs L, Mannaerts H, Kooiman E, Mevissen H, van der Heijden D, Hofmeyer H, Anscombe R, O'Meeghan T, Kjentjes M, Benatar J, Borthwick L, Doughty R, Copley M, Fisher R, Monkley R, Green B, Scott D, Hamer A, Tomlinson J, Hart H, Turner A, Cammell R, Troughton R, Skelton L, Young C, Kennett K, Claussen H, Hofsøy K, Melbue R, Sandvik J, Thunhaug H, Tveit A, Enger S, Bustamante G, Guillen MT, Cabrera J, Mendoza RE, Chavez C, Luna C, Lema J, Carrion A, Llerena N, Bedregal SA, Medina Palomino F, Rodriguez J, Minchola J, Bautista C, Negron Miguel S, Armas BH, Rodriguez A, Romero N, Torres P, Rodriguez KF, Yanac Chavez P, Delgado S, Sambaz CM, Barcinas R, Zapanta M, Coching R, Vallenas M, Matiga G, Enad C, Rogelio G, Joaquin F, Roxas A. Jr, Gilo L, To R, Aquino M, Villamor L, Nario K, Adamus J, Korzeniowska Adamus J, Baszak J, Bronisz M, Cieslak B, Busz Papiez B, Krzystolik A, Cymerman K, Dabrowska M, Ptak A, Derlaga B, Laskowska Derlaga E, Domanska E, Guziewicz M, Gieroba A, Zajac E, Gniot J, Mroczkowski P, Januszewicz A, Makowiecka Ciesla M, Jazwinska Tarnawska E, Ciezak P, Jurowiecki J, Kaczmarek B, Pacholska A, Kaminski L, Kania G, Tymendorf K, Karczmarczyk A, Kaliszczak R, Konieczny M, Benicka E, Korzeniak R, Borowski W, Krzyzanowski W, Muzyk Osikowicz M, Kus W, Lesnik J, Wierzykowski T, Lewczuk J, Stopyra Poczatek M, Lubinski A, Szymanska K, Lysek R, Jaguszewska G, Matyszczak Toniak L, Sznajder R, Wnetrzak Michalska R, Kosmaczewska A, Mazur S, Chmielowski A, Miekus P, Kosmalska K, Mosiewicz J, Myslinski W, Napora P, Biniek D, Nessler J, Nessler B, Niezgoda K, Nej A, Nowak J, Olszewski M, Podjacka D, Janczewska D, Pogorzelska H, Polaszewska Pulkownik V, Bojanowska E, Raczak G, Zienciuk Krajka A, Rewinska H, Rozmyslowicz Szerminska W, Ronkowski R, Norwa Otto B, Sendrowski D, Spyra J, Szolkiewicz M, Malanska A, Turbak R, Wrobel W, Muzalewski P, Wysokinski A, Kudlicki J, Zarebinski M, Krauze R, Zielinski M, Nawrot M, Matias F, Correia J, Gil V, Lopes S, Madeira J, Maymone D, Martins D, Neves E, Monteiro P, Oliveira D, Marques AL, Castro C, Salgado A, Gonçalves A, Sao Marcos H, Santos O, Nunes LV, Sao Teotonio H, Santos J, Soares D, Albulescu P, Ciortea M, Apetrei E, Matei C, Bartos D, Badila E, Bengus C, Ochean V, Bobescu E, Doka B, Bolohan F, Ciobotaru G, Andor M, Coman I, Ghionea M, Constantinescu M, Creteanu M, Parasteac M, Cristea M, Anciu M, Crisu D, Jemna D, Dobre I, Voicu O, Dobreanu D, Sirbu I, Dragomir D, Jurca S, Iosipescu L, Costache L, Minescu B, Serban D, Pop C, Cozma M, Popescu M, Ardelean A, Sipciu D, Plosca P, Stamate S, Spinu C, Topolnitchi L, Topolnitchi O, Tudoran M, Tudoran C, Zhukova N, Arutyunov G, Chernyavskaya T, Ballyuzek M, Alexandrova L, Barbarash O, Bashkireva A, Bart B, Larina V, Belenky D, Kosolapov Y, Berns S, Yukhno E, Bokarev I, Khlevchuk T, Chumakova G, Pokutneva O, Demko A, Masin A, Dovgalevsky P, Puchinyan N, Drapkina O, Zyatenkova E, Egorova L, Esip V, Kirichek N, Filatov A, Soin I, Gilinskaya O, Valuyshkih E, Glezer M, Valovyeva S, Golitsyn S, Kratskina T, Goloshchekin B, Laptev I, Gratsiansky N, Mazovets O, Karpov Y, Buza V, Kosenko B, Khirmanov V, Kireenkov I, Khokhlov A, Sinitsina O, Khokhlov R, Tsareva E, Khrustalev O, Khrustalev A, Kostenko V, Karabalieva S, Koziolova N, Polyanskaya E, Kozyrev O, Kostenko O, Kuznetsov V, Rychkov A, Lavrova O, Tereschenko L, Levashov S, Volkova E, Libis R, Maslova A, Libov I, Moiseeva Y, Lila A, Belousova L, Lukyanov Y, Lamden D, Nikolaev K, Nikolaev A, Nikolskaya I, Khromova O, Novikova N, Patrusheva S, Panchenko E, Laguta P, Panov A, Nilk R, Polkanova E, Matveeva I, Poluyanova N, Pikalova N, Raskina T, Letaeva M, Rebrov A, Karoli N, Repin M, Rodina N, Shaposhnik I, Lebedev E, Shogenov Z, Agirov M, Sidorenko B, Vorontsova S, Sinitsina I, Orlov V, Golshmid M, Sizova Z, Lapidus N, Sobolev K, Erofeeva S, Suprun E, Dronov D, Tarasov N, Isakov L, Tereshenko S, Kositsyna I, Tikhonova E, Solovyev A, Timofeev A, Bulygin S, Ustyugov S, Rossovskaya M, Vishnevsky A, Kirgizova A, Volkov D, Yakusevich V, Petrochenko A, Yakushin S, Nikulina N, Zateyshchikov D, Zotova I, Zateyshchikova A, Mankhaeva B, Zenin S, Kononenko O, Zubeeva G, Motylev I, Apostolovic S, Djordjevic Radojkovic D, Celic V, Majstorovic A, Cemerlic Adjic N, Bjelobrk M, Despotovic N, Erceg P, Ilic S, Ilic B, Krotin M, Djokovic A, Miloradovic V, Djokic I, Otasevic P, Tasic N, Potpara T, Polovina M, Putnikovic B, Kalezic T, Seferovic P, Milinkovic I, Tavciovski D, Davicevic Z, Vasiljevic Pokrajcic Z, Mitrovic P, Vujisic Tesic B, Tesic M, Ambrovicova V, Ambrovic I, Banikova A, Dukat A, Kosmalova V, Dulkova K, Dulka T, Vankova L, Dzupina A, Dzupinova M, Hatalova K, Hatala R, Hranai M, Hofmanova J, Kasperova V, Reptova A, Mazur J, Pella D, Fedacko J, Ruffini L, Morsky J, Slanina M, Kmec J, Zachar A, Kokles M, Zareczky P, Bollova D, Badenhorst J, Erasmus L, Basson M, Poynton M, Allman J, Ellis G, Botha L, Engelbrecht J, Mostert M, Essop M, Nunkoo T, Gani M, Wilson L, Kelfkens Y, Mitha I, Taljaard J, Naidoo D, Duki Y, Snyders F, Munnik M, Soma P, Johnston H, van der Merwe N, Goosen Y, van Zyl L, le Roux M, Venter T, Wessels L, Bae HJ, Han MG, Cha JK, Kim DH, Cho BR, Ryu DR, Choi HH, Hong KS, Chung WS, Oh YS, Han SH, Lee KH, Hong TJ, Lee HW, Hyon MS, Jung JW, Jeon HK, Lee JM, Kang DH, Choi KJ, Kim CJ, Jin ES, Kim DS, Seo JS, Kim HS, Cha MJ, Kim JT, Park MS, Kim JH, Park JH, Kim JS, Park SJ, Kim SH, Seo JB, Kim YJ, Chun MY, Lee MH, Joung BY, Lee SH, Shin DG, Namgung J, Kwak JJ, Rha SW, Na JO, Rim SJ, Kim JY, Arcocha Torres M, Rey AM, Blanco Coronado J, Puertas I, Bruguera Cortada J, Cabero P, Calvo C, Calvo G, de Arce Borda A, Asensio A, Diez Tejedor E, Guevara MP, Gonzalez Juanatey J, Moure M, Hernandez Madrid A, Delgado A, Lopez Garcia Aranda V, Barquero R, Manzano L, Abril SB, Merino J, Diaz Pintado M, Arias J, Fernandez M, Alvarez RF, Terns M, Delgado MD, Villuendas R, Astier L, Appelros P, Åkerberg A, Blom KB, Andersson R, Blomström P, Persson L, Carlsson T, Bengtsson AS, Dettmann S, Östberg S, Engdahl J, Karlsson L, Herlitz J, Winberg L, Jernhed H, Koskinen P, Håkansson E, Kozak P, Edlund M, Malmqvist L, Eriksson G, Randers F, Moodh J, Rautio A, Johansson M, Rönn F, Sundholm C, Stenberg A, Gunnarsson A, Thulin J, Broberg M, Slater IP, Cheng CC, Wu WS, Chiang CE, Yu WC, Chiang FT, Wu YW, Chiou CW, Yeh TC, Hsia CH, Chen YP, Huang JL, Chen YF, Kuo CT, Wang CL, Lai WT, Lin TH, Lee JT, Pai PY, Lin KH, Shyu KG, Chiu CZ, Tseng WK, Pan YF, Ueng KC, Lee SC, Wang JH, Tsai WC, Yeh HI, Kuo JY, Jirasirirojanakorn K, Pornchaiyasit K, Kaewsuwanna P, Sinthusopa W, Kiatchoosakun S, Sriprasert S, Laothavorn P, Bamrungpong P, Piyayotai D, Sripracha A, Panpunuan P, Sukonthasarn A, Mekara W, Vorasettakarnkij Y, Puripun E, Acikel M, Akilli H, Demir H, Ata N, Bayata S, Cakmak N, Calik A, Cayli M, Ceyhan C, Erdogan D, Ermis C, Kabul K, Kanadasi M, Turgut O, Tandogan I, Yalcin R, Yigit F, Yigit Z, Zoghi M, Batushkin V, Azhdari M, Bazylevych A, Vlasyuk Z, Bereznyakov I, Lebedynskaya M, Dotsenko S, Kulynych R, Dzyak G, Vasilyeva L, Faynyk A, Sorokivskyy M, Gavrysyuk V, Dzublik Y, Horbach L, Husyev V, Godlevska O, Samburg Y, Karpenko O, Nevolina I, Karpenko Y, Blihar O, Kaydashev I, Gerasimenko N, Kolomyyits S, Vasylets V, Kopytsya M, Petyunina O, Kotseruba V, Dvoieglazova M, Koval V, Ohirko O, Koval' O, Kaplan P, Kraiz I, Usan N, Kraydashenko O, Stets R, Kupnovytska I, Kyyak Y, Lizogub V, Gorna O, Malynovsky Y, Fedotov S, Ostrovska L, Ushakova Sokolova L, Dovgan N, Potapenko P, Nekrasa A, Prokhorov O, Leonidova V, Rebrov B, Gamachek O, Rishko M, Chendey T, Rudyk I, Shatilo V, Ishchuk V, Shcherbak V, Goncharova I, Shvetz N, Zamlynskyy M, Sirenko Y, Stanislavchuk M, Perebetiuk L, Sychov O, Lyzohub S, Tseluyko V, Kuznetsov I, Tykhonova S, Vakaliuk I, Drapchak I, Vatutin M, Sklyanna O, Vizir V, Goncharov O, Volkov V, Serik S, Yagensky A, Nahrebetskyy V, Yena L, Mudruk I, Zharinov O, Logvinov Y, Zhurba S, Shandra T, Aggarwal R, Smith S, Beeton I, Dunn S, Blagden M, Price R, Dougal K, Chapman O, Davies D, Choy A, Duff J, Cohen A, Wilmott R, D'Costa D, Douglas H, Dickinson D, Lie F, Ramasamy V, Lindsay S, Atkinson C, Linker N, Finlayson M, Lip G, Brown R, MacCallum P, Ebano P, MacLeod M, McGhee C, Marazzi P, Jones D, Maxwell T, Isted C, More R, Helliwell L, Moriarty A, Mackin A, Murdoch D, Andrews A, Newby D, Flint L, Pye M, Wright L, Avery D, Young G, Sopher M, Kennard S, Storey R, Bridge C, Turner W, Walker M, Venkataraman A, Gilchrist M, Watkin R, Chung A, Wright A, Wright J, Abi Mansour P, Panella M, Adams K, Lohman J, Adler J, Barash B, Adler P, Reiling S, Beck P, Ahmad A, Hussain A, Ahmadpour H, Lim G, Akhter F, Brubaker S, Alexander J, Genova Peeva E, Aliyar P, Godsey W, Allison J, Biscardi R, Almquist A, MacDonald H, Alsheikh T, Lane B, Amin K, Khetarpal S, Amin M, Persechino F, York T, Arnold T, Shoaf R, Arouni A, Rasmussen L, Attanti S, Strickland S, Aude Y, Cobos D, Awasty V, Baldwin E, Ayesu K, Thompson B, Baine S, Batista M, Baman R, Campbell G, Barber M, Altonen D, Barker T, Faircloth C, Barrington P, Gordon L, Bartkowiak A, Benton J, Beasley R, Hoffman T, Bedoya R, Luis Valdes M, Bedwell N, Craig M, Beinart S, Swaim D, Bensimhon D, Garman V, Berk M, Ibarra M, Bernard J, Eldred R, Bilal B, Preston S, Bilazarian S, Langone L, Bingham S, Antonino M, Block T, Talbot Lawson C, Blonder R, Ensminger E, Bloomberg R, Bloomberg K, Blue B, Vernon M, Borsheim M, Hickenbotham D, Bouchard A, Wade W, Bowden W, Ziegler K, Bradley A, Terry P, Brilakis E, Frey W, Brown H, Triano A, Bybee K, Al Maliky T, Cader C, Morton S, Canaday D, Canosa R, Hartranft E, Caplan J, Jameson L, Carr K, Phan D, Chang M, Hatfield G, Charlat M, Tamayo M, Chaturvedi S, Sawaya K, Ciaramita J, Bagby J, Clapp T, Clay A, McClelland M, Dutka C, Cohen R, Bossaers J, Colan D, Salpas S, Cole J, Fisher M, Concha M, Martinez E, Corbett B, Svadbik L, Cossu S, Mullinax K, Cottiero R, Masson E, Cowan L, Nelson L, Curtis B, Sarpola N, Dang N, Morgan T, Daniels S, Leka G, Datta S, Wulf A, Dave K, Dave B, Davuluri A, Ebreo N, De Lemos J, Debes C, Dean J, Warmack D, DeGarmo R, Carey J, Steward A, Desire A, Waters L, Devenport S, Briscoe C, Dhar S, Ucik S, DiGiovanna M, Tisdale L, Donovan D, Rodriguez L, Dotani I, Olson A, Drozdiak R, Habibi S, D'Souza A, Cullen T, Eade J, Dunn K, Eldadah Z, Quick R, Ellis J, Cristaldi J, Erenrich N, Johnson C, O'Brien J, Ettinger N, Shipp A, Everhart B, DeSalle D, Fahmy R, Watkins D, Feld L, Tameron A, Feldman J, Tang N, Felten W, Prior J, Fialkow J, Calvo M, Finkel M, Shriver D, Finkelstein S, Fischell T, Drew B, Fishbein G, Donahue S, Flores E, Slayton C, Forman S, Solis A, Frais M, Thrope C, Franco M, Gentry P, French W, Morales C, Friedlander I, Gaffney M, Jones J, Garb J, Miranda J, George F, Valentine H, Gerber J, Hinchion N, Gillespie E, Keane Richmond P, Gogia H, Ewing B, Goldscher D, Latteri J, Goldstein M, Gowda S, Rafala E, Graham S, Bonora M, Griffin S, Aull L, Griffin J, Goodman V, Grossman C, Davis A, Grove D, Mabe K, Guarino J, Gabela W, Guarnieri T, Guerrero, Foster B, Guthrie R, Felsman D, Gvora T, McLean R, Hack T, Morelli L, Hamroff G, Bentivenga L, Han M, Cavanna L, Harris J, Bobade M, Hearne S, Krater C, Heiman M, Dandekar U, Shah D, Henderson D, Millard D, Henry S, Harkins V, Hermany P, Batchell K, Herrod J, Miranda D, Herson S, Carey G, Hinchman D, Vieira P, Hippert R, Dutter S, Hoekstra J, Homan J, Homayouni A, Horton K, Sloss D, Hotchkiss D, Turner N, Houchin V, Howard V, Hays D, Howard L, Craft D, Huang P, Truva C, Hunter J, Battistelli E, Hurst P, Garza M, Hussain M, Tambawala M, Ison R, Butcher S, Jardula M, Andresen T, Johnson F, Phillips T, Jones R, Hughett G, Jovin I, Nichols M, Judson P, Royes A, Kahn B, Coombs V, Kai W, Dugal J, Kandath D, Kostedt G, Kaplan K, Cook S, Kapoor A, Ruggiero M, Karunaratne H, Behm K, Kastelic R, Davis C, Keller R, Keller J, Kerkering M, Bartholomaus D, Kersh R, Buhler A, Kesselbrenner M, DiCorcia L, Khan B, Binns M, Khan M, Khan G, Kindman L, Averett P, Korpas D, Godfrey C, Kotha P, Sanchez E, Kozlowski J, Watts S, Krichmar P, Marquez D, Laliotis A, Jauregui V, Lambert C, Coyle GS, Landau C, Ferguson D, Lang J, Simmons T, Langevin E, Faucett S, Ledbetter L, Royse H, Lentz M, Smith D, Lesser M, Hartley L, Lewis D, Bonds C, Lillestol M, Miller D, Ling L, Murphy R, Littlefield R, Wofford E, Lomnitz D, Lone B, Davids M, Looby R, Ault S, Lui H, Wright H, Lurie M, Edelstein J, Macomber J, Bush D, Magee A, Doctor A, Mainigi S, Lisiecki B, Makam S, Casas R, Mandviwala M, Marar I, Rabadi Marar D, Marenberg M, Bedenko E, Massin E, Hicks T, McCartney M, Stubbs L, McGarvey J, Schwarz L, McGuire K, McKenzie M, Rodkey K, McKnight T, Paul J, McLaurin B, Lack A, Mega J, Marti J, Meholick A, Skinner J, Mehrle A, Wall J, Mendelson R, Cervellione K, Mercado A, Cajulis C, Michlin B, Romero Colon J, Milas J, Sanders D, Miller R, Sanchez S, Miller S, Gryczan J, Mody F, Strugatsky S, Moran J, Garner S, Morledge J, Bowman B, Mouhaffel A, Parrott N, Mounsey P, Schuler C, Mowdy M, Todd S, Mullen P, Raziano S, Murphy A, Oehmann V, Nadar V, Parker A, Naidu J, West M, Nallasivan M, Goza J, Nguyen T, Nomanee S, Nielsen R, Wilmot M, Oberoi M, Thakkar N, Oppenheimer K, McCormick J, Orchard R, Garcia L, Osborne J, Gonzalez M, Oza S, Joseph L, Patnam S, Dennison K, Pavon H, Gorry N, Pearlstein R, Montayne S, Pentz W, Duncan D, Peters P, Chacon L, Petruzziello F, Morlando F, Pettis K, Brown F, Pezzella S, Kirk D, Poulathas A, Cush S, Pratt R, Neeper L, Pribble A, Lowe K, Pudi K, Sham L, Pugeda J, Ebert J, Quadrel M, Rafla E, Quinlan E, Reed C, Quinn J, Hemmen C, Rama P, Domingo D, Redondo V, Wroblewski J, Renzi M, Stanley E, Richwine R, Pazier P, Riofrio K, Braun D, Robinson J, Cherrico M, Roehll W, Hollihan P, Rosado, Barnhorst M, Rosado J, Bamhorst M, Rosen R, Martin C, Ross S, Freeman R, Ruoff G, Nelson T, Sacco J, Ball E, Samal A, Schomburg J, Sandberg J, Lafave J, Savin V, Clifton R, Schaefer S, Fekete A, Schneider R, Schneider W, Schulman D, Mercer S, Seals A, Ullig T, Holt A, Seide H, Mather N, Shah G, Witt P, Shalaby A, Seese M, Shanes J, Fleets J, Shaoulian E, Hren A, Sheikh K, Hengerer T, Shih H, Browning J, Shoukfeh M, Stephenson L, Siler T, Champagne M, Simpson P, Meyer R, Singh N, Turner K, Singh V, Nelson M, Skierka R, Hughes B, Keene R, Smith R, Hodnett P, Spangenthal S, Thomason L, Sperling M, Vasquez E, Spivack E, McCartney P, Staniloae C, Liu M, Steljes A, Cox C, Struble R, Vittitow T, Suresh D, Frost J, Swerchowsky V, Freemyer D, Szulawski I, Herwehe S, Tahirkheli N, Springer K, Takata T, Bruton T, Talano J, Leo L, Tami L, Corchado D, Tatarko M, Swauger M, Tawney K, Dastoli K, Teague S, Young K, Tee H, Mitchell T, Teixeira J, Southam D, Torres M, Tucker P, Salas L, Updegrove J, Hanna K, Val Mejias J, Harrelson KG, Vemireddy D, Cardoza T, Verma S, Parsons T, Vicari R, Warren K, Vijay N, Washam M, Vossler M, Kilcup S, Walsh R, Renaud K, Ward S, Locklear T, Waxman F, Sanchez G, Weiss R, St Laurent B, Westcott J, Williams D, Gibson C, Williams R, Dowling C, Willis J, VonGerichten S, Wood K, Capasso Gulve E, Worley S, Pointer S, Yarows S, Sheehan T, Yasin M, Yi J, Dongas B, Yousuf K, Zakhary B, Curtis S, Zeig S, Mason T, Zellner C, Harden M, Roper E, Waseem M, Grammer M., PERRONE FILARDI, PASQUALE, Cardiovascular Division (SZG), Brigham and Women's Hospital [Boston], Mount Sinai Medical Center, Icahn School of Medicine at Mount Sinai [New York] (MSSM), University Hospitals Case Medical Center (CLEVELAND - UHCMC), University Hospitals Case Medical Center, Jefferson Medical College (JMC), Thomas Jefferson University Hospitals, Thrombosis and Atherosclerosis Research Institute (TARI), McMaster University [Hamilton, Ontario], University Hospital Brno, Institute of Cardiology (WARSAW - Cardiology), Institute of Cardiology, Cardiology Research Center (MOSCOU - CRC), Cardiology Research Center, National Hopital Organization (OSAKA - NHO), Osaka National Hospital, Université de Brest (UBO), Centre d'Investigation Clinique (CIC - Brest), Université de Brest (UBO)-Institut National de la Santé et de la Recherche Médicale (INSERM), Graduate School, Endocrinology, ACS - Amsterdam Cardiovascular Sciences, Cardiology, Nursing, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, General Internal Medicine, Giugliano, Rp, Ruff, Ct, Braunwald, E, Murphy, Sa, Wiviott, Sd, Halperin, Jl, Waldo, Al, Ezekowitz, Md, Weitz, Ji, Špinar, J, Ruzyllo, W, Ruda, M, Koretsune, Y, Betcher, J, Shi, M, Grip, Lt, Patel, Sp, Patel, I, Hanyok, Jj, Mercuri, M, Antman, Em, Comi, Giancarlo, ENGAGE AF TIMI 48, Investigators, Robert P., Giugliano, Christian T., Ruff, Eugene, Braunwald, Sabina A., Murphy, Stephen D., Wiviott, Jonathan L., Halperin, Albert L., Waldo, Michael D., Ezekowitz, Jeffrey I., Weitz, Jind?ich, ?pinar, Witold, Ruzyllo, Mikhail, Ruda, Yukihiro, Koretsune, Joshua, Betcher, Minggao, Shi, Laura T., Grip, Shirali P., Patel, Indravadan, Patel, James J., Hanyok, Michele, Mercuri, Elliott M., Antman, Morin, Se, Hoffman, Eb, Deenadayalu, N, Grip, L, Lanz, H, Curt, V, Duggal, A, Hanyok, J, Davé, J, Morgan, D, Choi, Y, Jin, J, Xie, J, Crerand, W, Kappelhof, J, Maxwell, W, Skinner, M, Patel, S, Selicato, G, Otto C., Jr, Reissner, C, Smith, K, Ostroske, J, Ron, A, Giugliano, R, Connolly, S, Camm, J, Ezekowitz, M, Halperin, J, Waldo, A, Paolasso, E, Aylward, P, Heidbuchel, H, Nicolau, Jc, Goudev, A, Roy, D, Weitz, J, Corbalán, R, Yang, Y, Botero, R, Bergovec, M, Ŝpinar, J, Grande, P, Hassager, C, Voitk, J, Huikuri, H, Nieminen, M, Blanc, Jj, Leheuzey, Jy, Mitrovic, V, Alexopoulos, D, Sotomora, G, Kiss, R, Somaraju, B, Lewis, B, Merlini, P, Metra, M, Yamashita, T, García Castillo, A, Ophuis, T, White, H, Atar, D, Horna, M, Babilonia, N, Morais, J, Dorobantu, M, Ostojic, M, Duris, T, Dalby, A, Chung, N, Zamorano, Jl, Juul Möller, S, Moccetti, T, Chen, Sa, Sritara, P, Oto, A, Parkhomenko, A, Senior, R, Verheugt, F, Skene, A, Anderson, J, Bauer, K, Easton, Jd, Goto, S, Wiviott, S, Lowe, C, Awtry, E, Berger, Cj, Croce, K, Desai, A, Gelfand, E, Goessling, W, Greenberger, Nj, Ho, C, Leeman, De, Link, M, Norden, Ad, Pande, A, Rost, N, Ruberg, F, Silverman, S, Singhal, A, Vita, Ja, Vogelmann, O, Gonzalez, C, Ahuad Guerrero, R, Rodriguez, M, Albisu, J, Rosales, E, Allall, O, Reguero, M, Alvarez, C, Garcia, M, Ameriso, S, Ameriso, P, Amuchastegui, M, Caceres, M, Beloscar, J, Petrucci, J, Berli, M, Budassi, N, Valle, M, Bustamante Labarta, G, Saravia, M, Caccavo, A, Fracaro, V, Cartasegna, L, Novas, V, Caruso, O, Zarandon, R, Colombo, H, Morandini, M, Cuello, J, Rosell, M, Cuneo, C, Bocanera, M, D'Amico, A, Cendali, G, Dran, R, Moreno, V, Estol, C, Davolos, M, Facello, A, Facello, M, Falu, E, Iriarte, M, Femenia, F, Arrieta, M, Fuselli, J, Zanotti, A, Gant Lopez, J, Meiller, F, Garcia Duran, R, Perlo, D, Garrido, M, Ceirano, C, Giacomi, G, Eden, M, Giannaula, R, Huerta, M, Goicoechea, R, von Wulffen, M, Hominal, M, Bianchini, M, Jure, H, Jure, D, Kevorkian, R, Monaco, F, Lanternier, G, Belcuore, M, Liniado, G, Iglesias, M, Litvak, B, Nigro, A, Llanos, J, Vignau, S, Lorente, C, Shatsky, K, Lotti, J, Raimondi, G, Mackinnon, I, Carne, M, Manuale, O, Calderon, M, Marino, J, Funes, I, Muntaner, J, Gandur, H, Nul, D, Verdini, E, Piskorz, D, Tommasi, A, Povedano, G, Casares, E, Pozzer, D, Fernandez, E, Prado, A, Venturini, C, Ramos, H, Navarrete, S, Alvarez, M, Sanchez, A, Bowen, L, Sanjurjo, M, Codutti, O, Saravia Toledo, S, Formoso, I, Schmidberg, J, Goloboulicz, A, Schygiel, P, Buzzetti, C, Severino, P, Morara, P, Sosa Liprandi, M, Teves, M, Vico, M, Morell, Y, Anderson, C, Paraskevaidis, T, Arstall, M, Hoffmann, B, Colquhoun, D, Price Smith, S, Crimmins, D, Slattery, A, Dart, A, Kay, S, Davis, S, Silver, G, Flecknoe Brown, S, Roberts, J, Gates, P, Jones, S, Lehman, R, Morrison, H, Mckeirnan, M, Li, J, Paul, V, Batta, C, Purnell, P, Perrett, L, Szto, G, O'Shea, V, Capiau, L, Banaeian, F, De Bleecker, J, de Koning, K, De Tollenaere, M, De Bruyne, L, Desfontaines, P, Tincani, G, Meeusen, K, Herzet, J, Malmendier, D, Mairesse, G, Raepers, M, Parqué, J, Clinckemaille, N, Scavée, C, Huyberechts, D, Stockman, D, Jacobs, C, Vandekerckhove, Y, Derycker, K, Vanwelden, J, van Welden, J, Vervoort, G, Mestdagh, I, Vrolix, M, Beerts, C, Wollaert, B, Denie, D, Amato Vincenzo de Paola, A, Coutinho, E, Andrade Lotufo, P, de Melo, Rf, Atie, J, Motta, C, Augusto Alves da Costa, F, Ferraz, Rf, Bertolim Precoma, D, Sehnem, E, Botelho, R, Cunha, S, Brondani, R, Fleck, N, Chaves Junior, H, Silva, J, Costantini, C, Barroso, D, De Patta, M, Pereira, V, Duda, N, Laimer, R, Dutra, O, Morgado, S, Faustino Saporito, W, Seroqui, M, Ferreira, L, Araújo, E, Finimundi, H, Daitz, C, Gagliardi, R, Pereira, G, Gomes, M, Gomes, A, Guimarães, A, Ninho, L, Jaeger, C, Pereira, L, Jorge, J, Cury, C, Kaiser, S, Almeida, A, Kalil, C, Radaelli, G, Kunz Sebba Barroso de Souza, W, Morales, K, Leaes, P, Luiz, Ro, Pimenta Almeida, J, Gozalo, A, Reis, G, Avellar, K, Reis Katz Weiand, L, Leipelt, J, Rocha, J, Barros, R, Rodrigues, L, Rocha, Mr, Rodrigues, A, Rodrigues, D, Rossi dos Santos, F, Pagnan, Lg, Sampaio, R, do Val, R, Saraiva, J, Vicente, C, Simoes, M, Carraro, A, Sobral Filho, D, Lustosa, E, Villas Boas, F, Almeida, M, Zimmermann, S, Zimmermann, Eb, Chompalova, B, Parishev, G, Denchev, S, Milcheva, N, Donova, T, Gergova, V, Georgiev, B, Kostova, E, Kinova, E, Hergeldjieva, V, Kamenova, P, Manolova, A, Vasilev, I, Mihov, A, Miteva, B, Mincheva, V, Stoyanovski, V, Nikolov, F, Vasilev, D, Pencheva, G, Kostov, K, Petranov, S, Milusheva, T, Popov, A, Staneva, A, Momchilova Lozeva, D, Todorov, G, Nyagina, M, Tumbev, H, Tumbeva, D, Tzekova, M, Kitova, M, Manoylov, E, Archibald, J, Antle, S, Bhargava, R, Stafford, C, Bose, S, Hundseth, M, Cha, J, Otis, J, Chehayeb, R, Lepage, C, Chilvers, M, Vansickle, L, Cleveland, D, Valley, S, Constance, C, Gauthier, M, Costi, P, Masson, C, Coutu, B, Denis, I, du Preez, M, Kubanska, A, Dufresne, M, Krider, J, Eikelboom, J, Zondag, M, Fortin, C, Viau, C, Green, M, Houbraken, D, Hatheway, R, Mabee, J, Heath, J, Scott, L, Ho, K, Ho, V, Hoag, G, Standring, R, Huynh, T, Perkins, L, Kouz, S, Roy, M, Labonte, R, Dewar, C, Lainesse, A, St Germain, L, Lam, S, Lam, H, Lichtenstein, T, Roberts, P, Luton, R, Douglas, S, Ma, P, Seib, M, Maccallum, C, Matthews, J, Malette, P, Vaillancourt, T, Maranda, C, Studenikow, E, Mawji, A, Morely, A, Morrison, D, Roth, M, Mucha, M, Najarali, A, Lamoureux, U, Nicholson, R, O'Hara, G, Banville, P, O'Mahony, W, Bolton, R, Parkash, R, Carroll, L, Pesant, Y, Sardin, V, Polasek, P, Turri, L, Qureshi, A, Nethercott, C, Ricci, J, Bozek, B, Rupka, D, Marchand, C, Shu, D, Silverio, G, St Hilaire, R, Morissette, A, Sussman, J, Kailey, P, Syan, G, Bobbie, C, Talajic, M, David, D, Talbot, P, Tremblay, M, Teitelbaum, I, Teitelbaum, J, Velthuysen, G, Giesbrecht, L, Wahby, R, Morley, A, Wharton, S, Caterini, T, Woodford, T, Balboa, W, Matus, Lr, Bugueño, C, Mondaca, Pm, Cobos, J, Obreque, C, Corbalan, R, Parada, A, Florenzano, F, Diaz, Pa, Lopetegui, M, Rebolledo, C, Manriquez, L, Silva, Lm, Martinez, D, Llamas, Rr, Opazo, M, Pérez, Mc, Pincetti, C, Carrasco, Gt, Potthoff, S, Staub, Jz, Campisto, Y, Stockins, B, Lara, Cl, Yovaniniz, P, Azua, Mg, Bai, F, Xu, Gl, Chen, Jz, Xie, Xd, Chen, Xp, Zhang, X, Dong, Yg, Feng, C, Fu, G, Zhang, P, Hong, K, You, Zg, Hong, L, Qiu, Y, Jiang, Xj, Qu, Z, Li, L, Liu, H, Li, Tf, Kong, Yq, Li, Wm, Liu, B, Li, Zq, Liu, Y, Liao, Dn, Gu, Xj, Liu, L, Lu, Zh, Ma, Sm, Yang, Zy, Wang, Dm, Qi, Sy, Wang, Gp, Shi, Xj, Wei, M, Huang, D, Wu, Sl, Li, Ye, Xu, Jh, Gu, Jy, Xu, Ym, Liang, Yz, Yang, K, Li, Ay, Yang, Yj, Zheng, X, Zheng, Y, Gao, M, Yin, Yh, Xu, Yp, Yu, B, Li, Ll, Yuan, Zy, Qiang, H, Zhang, Hq, Lin, Yn, Zhang, Z, Kang, H, Zhao, Rp, Han, Rj, Zhao, Xl, Wang, Jq, Zheng, Zq, Li, Bg, Zhou, Sx, Zhang, Yl, Accini, J, Accini, M, Cano, N, Pineda, Ll, Delgado Restrepo, J, Arroyave, C, Fernández Ruiz, R, Diaz, Ia, Hernandez, H, Delgado, P, Jaramillo Muñoz, C, Builes, A, Manzur, F, Rodriguez, Er, Moncada Corredor, M, Giraldo, Dl, Orozco Linares, L, Fonseca, J, Quintero, A, Gonzales, C, Sanchez Vallejo, G, Mejia, Ip, Bagatin, J, Carevic, V, Car, S, Jeric, M, Ciglenecki, N, Tusek, S, Ferri Certic, J, Romic, I, Francetic, I, Ausperger, Km, Jelic, V, Jurinjak, Sj, Knezevic, A, Buksa, B, Samardzic, P, Lukenda, Kc, Steiner, R, Kirner, D, Sutalo, K, Bakliza, Z, Vrazic, H, Lucijanic, T, Bar, M, Brodova, P, Berka, L, Kunkelova, V, Brtko, M, Burianova, H, Cermak, O, Elbl, L, Ferkl, R, Florian, J, Francek, L, Golan, L, Gregor, P, Honkova, M, Hubac, J, Jandik, J, Jarkovsky, P, Jelinek, Z, Jerabek, O, Jirmar, R, Kobza, R, Kochrt, M, Kostkova, G, Kosek, Z, Kovar, P, Kuchar, R, Kvasnicka, J, Ludka, O, Machova, V, Krocova, E, Melichar, M, Nechanicky, R, Olsr, J, Peterka, K, Petrova, I, Havlova, I, Pisova, J, Podrazil, P, Jirsova, E, Reichert, P, Slaby, J, Spacek, R, Spinar, J, Labrova, R, Vodnansky, P, Samkova, D, Zidkova, E, Dodt, K, Christensen, H, Christensen, L, Loof, A, Ibsen, H, Madsen, H, Iversen, H, Veng Olsen, T, Nielsen, H, Olsen, R, Overgaard, K, Petrovic, V, Raymond, I, Raae, D, Sand, N, Svenningsen, A, Torp Pedersen, C, Jakobsen, U, Wiggers, H, Serup Hansen, K, Kaik, J, Stern, A, Kolk, R, Laane, E, Rivis, L, Paumets, M, Laheäär, M, Rosenthal, A, Rajasalu, R, Vahula, V, Ratnik, E, Kaarleenkaski, S, Hussi, E, Valpas, S, Jäkälä, P, Lappalainen, T, Mäenpää, A, Viitaniemi, J, Nyman, K, Sankari, T, Rasi, H, Salminen, O, Virtanen, V, Nappila, H, Le Heuzey, J, Agraou, B, El Jarroudi, F, Amarenco, P, Boursin, P, Babuty, D, Boyer, M, Belhassane, A, Berbari, H, Blanc, J, Dias, P, Coisne, D, Berger, N, Decoulx, E, El Jarroudi, M, Dinanian, S, Arfaoui, M, Hermida, J, Deruche, E, Kacet, S, Corbut, S, Poulard, J, Leparree, S, Roudaut, R, Duprat, C, Al Zoebi, A, Wurow, A, Bernhardt, P, Dichristin, U, Berrouschot, J, Vierbeck, S, Beyer Westendorf, J, Sehr, B, Bouzo, M, Schnelzer, P, Braun, R, Ladenburger, K, Buhr, M, Weihrauch, D, Contzen, C, Kara, M, Daut, W, Ayasse, D, Degtyareva, E, Kranz, P, Drescher, T, Herfurth, B, Faghih, M, Forck Boedeker, K, Schneider, K, Fuchs, R, Manuela, W, Grigat, C, Otto, A, Hartmann, A, Peitz, M, Heuer, H, Dieckheuer, U, Hoffmann, U, Dorn, S, Hoffmann, S, Schuppe, M, Horacek, T, Fink, P, Junggeburth, J, Schmid, S, Jungmair, W, Schoen, B, Kleinecke Pohl, U, Meusel, P, Koenig, H, Bauch, F, Lohrbaecher Kozak, I, Grosse, B, Lueders, S, Venneklaas, U, Luttermann, M, Wulf, M, Maus, O, Hoefer, K, Meissner, G, Braemer, U, Meyer Pannwitt, U, Frahm, E, Vogt, S, Muegge, A, Barbera, S, Mueller Glamann, M, Raddatz, K, Piechatzek, R, Lewinsky, D, Pohl, W, Proskynitopoulos, N, Kuhlmann, M, Rack, K, Pilipenko, H, Rinke, A, Kühlenborg, A, Schaefer, A, Szymanowski, N, Schellong, S, Frommhold, R, Schenkenberger, I, Finsterbusch, T, Dreykluft, K, Schiewe, C, Schmidt, A, Schmidt, M, Schreckenberg, A, Hellmers, J, Seibert, H, Gold, G, Sohn, H, Baylacher, M, Spitzer, S, Bonin, K, Stoehring, R, Taggeselle, J, Zarpentin, C, Veltkamp, R, Ludwig, I, Voehringer, Buchholz, M, Weyland, K, Winkelmann, B, Buelow Johansen, B, Wolde, C, Winter, K, Mavronasiou, E, Bourlios, P, Tziortziotis, A, Karamitsos, C, Exarchou, E, Kifnidis, K, Daskalaki, A, Moschos, N, Dimitra, K, Olympios, C, Kartsagkoulis, E, Pyrgakis, V, Korantanis, K, Ayau Milla, O, Ramirez Vde, L, Guzman Melgar, I, Jimenez, T, Ovando Lavagnino, A, Guevara, S, Rodas Estrada, M, Sanchez, M, Pozuelos, Jm, Sanchez Samayoa, C, Guerra, L, Velasquez Camas, L, Almaraz, Sp, Dioszeghy, P, Muskoczki, E, Edes, I, Szatmari, J, Fiok, J, Varga, A, Kanakaridisz, N, Kosztyu, M, Kis, E, Feil, Jf, Jakal, A, Koczka, M, Kovacs, I, Baranyai, M, Kovacs, Z, Lupkovics, G, Karakai, Hh, Matoltsy, A, Kiss, T, Medvegy, M, Kiss, K, Merkely, B, Kolumban, E, Nagy, A, Palinkas, A, Toth, Sr, Sayour, A, Bognar, A, Simor, T, Ruzsa, D, Sipos, T, Szakal, I, Tomcsanyi, J, Marosi, A, Vertes, A, Kincses, M, Malhan, S, Abdullakutty, J, Agarwal, D, Ranka, R, Arneja, J, Memon, A, Arora, V, Shree, R, Avvaru, G, Shaikh, A, Babu, P, Rao, B, Babu, R, Reddy, J, Banker, D, Sheth, T, Benjarge, P, Surushe, S, Bharani, A, Solanki, R, Bhargava, V, Rathi, A, Biniwale, A, Bhuti, M, Calambur, N, Karnwal, N, Chopda, M, Mali, N, Goyal, N, Saini, A, Gupta, J, Singh, P, Hadan, S, Savanth, P, Hardas, S, Thakor, G, Hiremath, J, Ghume, A, Jain, R, Pahuja, M, Joseph, S, Oommen, D, Joseph, J, Thomas, R, Joshi, H, Iby, Kale, V, Raut, N, Kandekar, B, Kandekar, S, Kishore, R, Krishnan, H, Kotiwale, V, Kulkarni, R, Deokar, M, Kulkarni, G, Lawande, A, Kumar, P, Karpuram, M, Kumar, A, Francis, J, Kumbla, M, Anthony, A, Lavhe, P, Kale, M, Mardikar, H, Bhaskarwar, P, Mathur, A, Sharma, P, Menon, J, Francis, V, Namjoshi, D, Shelke, S, Narendra, J, Natarajan, S, Oomaan, A, Gurusamy, P, Angel, J, Purayil, Mp, Shams, S, Pandurangi, U, Sababathi, R, Parekh, P, Jasani, B, Patki, N, Babbar, A, Pinto, B, Kharalkar, H, Premchand, R, Jambula, H, Rao, M, Vuriya, A, Ravi Shankar, A, Reddy, R, Bekal, S, Barai, A, Saha, D, Gadepalli, R, Sant, H, Jadhav, D, Sarna, M, Arora, T, Sawhney, J, Singh, R, Sethi, K, Bansal, N, Sethia, A, Sethia, S, Shetty, G, Sudheer, R, Singh, G, Gupta, R, Srinivas, A, Thankaraj, L, Varma, S, Kaur, A, Vinod, Mv, Thakur, B, Zanwar, I, Dharmarao, A, Atar, S, Lasri, E, Dicker, D, Marcoviciu, D, Elias, M, Ron, Ga, Francis, A, Ghantous, R, Goldhaber, A, Goldhaber, M, Gottlieb, S, Rouwaida, S, Grossman, E, Dagan, T, Hasin, Y, Roshrosh, M, Hayek, T, Majdoub, A, Klainman, E, Genin, I, Lahav, M, Gilat, T, Ben Ari, M, Lishner, M, Karny, M, Ouzan, E, Givoni, H, Rozenman, Y, Logvinenko, S, Schiff, E, Sterlin, J, Shochat, M, Aloni, I, Swissa, M, Belatsky, V, Tsalihin, D, Kisos, D, Zeltser, D, Platner, N, Berni, A, Giovannelli, F, Boriani, G, Cervi, E, Comi, G, Peruzzotti, L, Cuccia, C, Forgione, C, De Caterina, R, De Pace, D, De Servi, S, Mariani, M, Di Lenarda, A, Mazzone, C, Di Pasquale, G, Di Niro, M, Fattore, L, Bosco, B, Grassia, V, Murena, E, Laffi, Gaggioli, G, Lo Pinto, G, Raggi, F, Marino, P, Francalacci, G, Babbolin, M, Bulgari, M, Penco, M, Lioy, E, PERRONE FILARDI, Pasquale, Marciano, C, Pirelli, S, Paradiso, G, Piseddu, G, Fenu, L, Raisaro, A, Granzow, K, Rasura, M, Cannoni, S, Severi, S, Breschi, M, Toschi, V, Gagliano, M, Zacà, V, Furiozzi, F, Hirahara, T, Akihisa, U, Masaki, W, Ajioka, M, Matsushita, C, Anzai, T, Mino, K, Arakawa, S, Tsukimine, A, Endo, H, Fujiwara, M, Fujii, K, Kozeni, S, Fujii, E, Kotera, M, Fujimoto, S, Omae, K, Fujimoto, K, Ichishita, Y, Fujita, T, Ito, Y, Fukamizu, S, Harada, J, Fukuda, N, Fujimoto, C, Funazaki, T, Yamaguchi, A, Furukawa, Y, Kamitake, C, Hagiwara, N, Naganuma, M, Hara, S, Kumagai, S, Harada, K, Fuki, Y, Haruna, T, Nakahara, Y, Hashimoto, Y, Shimazu, Y, Hiasa, Y, Oga, Y, Higashikata, T, Nakagawa, Y, Hirayama, A, Kawaguchi, A, Iesaka, Y, Miyamoto, C, Iijima, T, Higuchi, K, Ino, H, Noguchi, H, Inomata, T, Nakamura, K, Ishibashi, Y, Nozaki, T, Ishii, Y, Tomita, H, Ishimaru, S, Ise, M, Itamoto, K, Ito, T, Onishi, M, Iwade, K, Sakuma, Y, Iwasaki, T, Nagatome, H, Kakinoki, S, Adachi, C, Kamakura, S, Nakahara, F, Kamijo, M, Iida, S, Kamiyama, K, Fujii, R, Kato, K, Ishida, A, Kazatani, Y, Ichikawa, Y, Kitazawa, H, Igarashi, C, Kobayashi, Y, Kikuchi, R, Kohno, M, Tamura, S, Yumoto, I, Kurabayashi, M, Koya, E, Masuyama, T, Kaneno, Y, Matsuda, K, Ebina, E, Meno, H, Satake, M, Mita, T, Takeda, M, Miyamoto, N, Kimizu, T, Miyauchi, Y, Sakamoto, S, Munemasa, M, Murata, J, Nagai, Y, Sakata, Y, Naito, S, Oyama, H, Nishi, Y, Nagase, T, Ochiai, J, Junko, H, Ogawa, T, Sugeno, M, Oguro, H, Tanabe, M, Okada, K, Moriyama, Y, Okajima, K, Nakashima, M, Okazaki, O, Wada, H, Okishige, K, Kitani, S, Okumura, K, Narita, Y, Onaka, H, Moriyama, H, Ozaki, Y, Tanikawa, I, Sakagami, S, Nakano, A, Sakuragi, S, Hayashi, N, Sakurai, S, Ooki, H, Sasaki, T, Oosawa, N, Satoh, A, Fujimoto, E, Seino, Y, Narumi, M, Shirai, T, Shigenari, M, Shoji, Y, Ueda, J, Sugi, K, Miyazaki, E, Sumii, K, Asakura, H, Takagi, M, Mohri, S, Takahashi, W, Yoshida, K, Takahashi, A, Kishi, N, Takahashi, T, Sakurai, Y, Takeda, K, Yahata, A, Takenaka, T, Yamagishi, K, Takeuchi, S, Watanabe, E, Tanaka, K, Uchida, M, Tanouchi, J, Nishiya, Y, Tsuboi, H, Tsuboi, N, Terakura, K, Uematsu, M, Yasumoto, S, Ueyama, Y, Usuda, K, Sakai, Y, Yagi, M, Sato, A, Yagi, H, Kuroda, T, Yamabe, H, Sakamoto, Y, Yamada, T, Yamano, R, Yamagishi, T, Sasaki, S, Yamamoto, Y, Yamashina, A, Takiguchi, M, Yonehara, T, Yoshino, H, Nomura, H, Yoshioka, K, Fujiwara, Y, Bayram Llamas, E, Hurtado, A, Calvo Vargas, C, Limon, Mc, Cardona Muñoz, E, Hernandez, S, Carrillo, J, Delgadillo, T, Cásares Ramirez, M, Valles, Jf, Garcia, N, Colin, Ma, Garcia Castillo, A, Jaramillo, A, Leiva Pons, J, de la Mora, S, Llamas Esperón, G, Grajales, A, Mendez Machado, G, Avila, H, Ruiz, Ln, Magallanes, G, Sánchez Díaz, C, Ortiz, A, Sánchez, Rv, Velazquez, Em, Alhakim, M, van Welsen, I, Bruning, T, Jones, A, Buiks, C, de Groot, J, Radder, I, de Vos, R, Hazeleger, R, Daniels, R, Kietselaer, B, Muijs, L, Mannaerts, H, Kooiman, E, Mevissen, H, van der Heijden, D, Hofmeyer, H, Anscombe, R, O'Meeghan, T, Kjentjes, M, Benatar, J, Borthwick, L, Doughty, R, Copley, M, Fisher, R, Monkley, R, Green, B, Scott, D, Hamer, A, Tomlinson, J, Hart, H, Turner, A, Cammell, R, Troughton, R, Skelton, L, Young, C, Kennett, K, Claussen, H, Hofsøy, K, Melbue, R, Sandvik, J, Thunhaug, H, Tveit, A, Enger, S, Bustamante, G, Guillen, Mt, Cabrera, J, Mendoza, Re, Chavez, C, Luna, C, Lema, J, Carrion, A, Llerena, N, Bedregal, Sa, Medina Palomino, F, Rodriguez, J, Minchola, J, Bautista, C, Negron Miguel, S, Armas, Bh, Rodriguez, A, Romero, N, Torres, P, Rodriguez, Kf, Yanac Chavez, P, Delgado, S, Sambaz, Cm, Barcinas, R, Zapanta, M, Coching, R, Vallenas, M, Matiga, G, Enad, C, Rogelio, G, Joaquin, F, Roxas A., Jr, Gilo, L, To, R, Aquino, M, Villamor, L, Nario, K, Adamus, J, Korzeniowska Adamus, J, Baszak, J, Bronisz, M, Cieslak, B, Busz Papiez, B, Krzystolik, A, Cymerman, K, Dabrowska, M, Ptak, A, Derlaga, B, Laskowska Derlaga, E, Domanska, E, Guziewicz, M, Gieroba, A, Zajac, E, Gniot, J, Mroczkowski, P, Januszewicz, A, Makowiecka Ciesla, M, Jazwinska Tarnawska, E, Ciezak, P, Jurowiecki, J, Kaczmarek, B, Pacholska, A, Kaminski, L, Kania, G, Tymendorf, K, Karczmarczyk, A, Kaliszczak, R, Konieczny, M, Benicka, E, Korzeniak, R, Borowski, W, Krzyzanowski, W, Muzyk Osikowicz, M, Kus, W, Lesnik, J, Wierzykowski, T, Lewczuk, J, Stopyra Poczatek, M, Lubinski, A, Szymanska, K, Lysek, R, Jaguszewska, G, Matyszczak Toniak, L, Sznajder, R, Wnetrzak Michalska, R, Kosmaczewska, A, Mazur, S, Chmielowski, A, Miekus, P, Kosmalska, K, Mosiewicz, J, Myslinski, W, Napora, P, Biniek, D, Nessler, J, Nessler, B, Niezgoda, K, Nej, A, Nowak, J, Olszewski, M, Podjacka, D, Janczewska, D, Pogorzelska, H, Polaszewska Pulkownik, V, Bojanowska, E, Raczak, G, Zienciuk Krajka, A, Rewinska, H, Rozmyslowicz Szerminska, W, Ronkowski, R, Norwa Otto, B, Sendrowski, D, Spyra, J, Szolkiewicz, M, Malanska, A, Turbak, R, Wrobel, W, Muzalewski, P, Wysokinski, A, Kudlicki, J, Zarebinski, M, Krauze, R, Zielinski, M, Nawrot, M, Matias, F, Correia, J, Gil, V, Lopes, S, Madeira, J, Maymone, D, Martins, D, Neves, E, Monteiro, P, Oliveira, D, Marques, Al, Castro, C, Salgado, A, Gonçalves, A, Sao Marcos, H, Santos, O, Nunes, Lv, Sao Teotonio, H, Santos, J, Soares, D, Albulescu, P, Ciortea, M, Apetrei, E, Matei, C, Bartos, D, Badila, E, Bengus, C, Ochean, V, Bobescu, E, Doka, B, Bolohan, F, Ciobotaru, G, Andor, M, Coman, I, Ghionea, M, Constantinescu, M, Creteanu, M, Parasteac, M, Cristea, M, Anciu, M, Crisu, D, Jemna, D, Dobre, I, Voicu, O, Dobreanu, D, Sirbu, I, Dragomir, D, Jurca, S, Iosipescu, L, Costache, L, Minescu, B, Serban, D, Pop, C, Cozma, M, Popescu, M, Ardelean, A, Sipciu, D, Plosca, P, Stamate, S, Spinu, C, Topolnitchi, L, Topolnitchi, O, Tudoran, M, Tudoran, C, Zhukova, N, Arutyunov, G, Chernyavskaya, T, Ballyuzek, M, Alexandrova, L, Barbarash, O, Bashkireva, A, Bart, B, Larina, V, Belenky, D, Kosolapov, Y, Berns, S, Yukhno, E, Bokarev, I, Khlevchuk, T, Chumakova, G, Pokutneva, O, Demko, A, Masin, A, Dovgalevsky, P, Puchinyan, N, Drapkina, O, Zyatenkova, E, Egorova, L, Esip, V, Kirichek, N, Filatov, A, Soin, I, Gilinskaya, O, Valuyshkih, E, Glezer, M, Valovyeva, S, Golitsyn, S, Kratskina, T, Goloshchekin, B, Laptev, I, Gratsiansky, N, Mazovets, O, Karpov, Y, Buza, V, Kosenko, B, Khirmanov, V, Kireenkov, I, Khokhlov, A, Sinitsina, O, Khokhlov, R, Tsareva, E, Khrustalev, O, Khrustalev, A, Kostenko, V, Karabalieva, S, Koziolova, N, Polyanskaya, E, Kozyrev, O, Kostenko, O, Kuznetsov, V, Rychkov, A, Lavrova, O, Tereschenko, L, Levashov, S, Volkova, E, Libis, R, Maslova, A, Libov, I, Moiseeva, Y, Lila, A, Belousova, L, Lukyanov, Y, Lamden, D, Nikolaev, K, Nikolaev, A, Nikolskaya, I, Khromova, O, Novikova, N, Patrusheva, S, Panchenko, E, Laguta, P, Panov, A, Nilk, R, Polkanova, E, Matveeva, I, Poluyanova, N, Pikalova, N, Raskina, T, Letaeva, M, Rebrov, A, Karoli, N, Repin, M, Rodina, N, Shaposhnik, I, Lebedev, E, Shogenov, Z, Agirov, M, Sidorenko, B, Vorontsova, S, Sinitsina, I, Orlov, V, Golshmid, M, Sizova, Z, Lapidus, N, Sobolev, K, Erofeeva, S, Suprun, E, Dronov, D, Tarasov, N, Isakov, L, Tereshenko, S, Kositsyna, I, Tikhonova, E, Solovyev, A, Timofeev, A, Bulygin, S, Ustyugov, S, Rossovskaya, M, Vishnevsky, A, Kirgizova, A, Volkov, D, Yakusevich, V, Petrochenko, A, Yakushin, S, Nikulina, N, Zateyshchikov, D, Zotova, I, Zateyshchikova, A, Mankhaeva, B, Zenin, S, Kononenko, O, Zubeeva, G, Motylev, I, Apostolovic, S, Djordjevic Radojkovic, D, Celic, V, Majstorovic, A, Cemerlic Adjic, N, Bjelobrk, M, Despotovic, N, Erceg, P, Ilic, S, Ilic, B, Krotin, M, Djokovic, A, Miloradovic, V, Djokic, I, Otasevic, P, Tasic, N, Potpara, T, Polovina, M, Putnikovic, B, Kalezic, T, Seferovic, P, Milinkovic, I, Tavciovski, D, Davicevic, Z, Vasiljevic Pokrajcic, Z, Mitrovic, P, Vujisic Tesic, B, Tesic, M, Ambrovicova, V, Ambrovic, I, Banikova, A, Dukat, A, Kosmalova, V, Dulkova, K, Dulka, T, Vankova, L, Dzupina, A, Dzupinova, M, Hatalova, K, Hatala, R, Hranai, M, Hofmanova, J, Kasperova, V, Reptova, A, Mazur, J, Pella, D, Fedacko, J, Ruffini, L, Morsky, J, Slanina, M, Kmec, J, Zachar, A, Kokles, M, Zareczky, P, Bollova, D, Badenhorst, J, Erasmus, L, Basson, M, Poynton, M, Allman, J, Ellis, G, Botha, L, Engelbrecht, J, Mostert, M, Essop, M, Nunkoo, T, Gani, M, Wilson, L, Kelfkens, Y, Mitha, I, Taljaard, J, Naidoo, D, Duki, Y, Snyders, F, Munnik, M, Soma, P, Johnston, H, van der Merwe, N, Goosen, Y, van Zyl, L, le Roux, M, Venter, T, Wessels, L, Bae, Hj, Han, Mg, Cha, Jk, Kim, Dh, Cho, Br, Ryu, Dr, Choi, Hh, Chung, W, Oh, Y, Han, Sh, Lee, Kh, Hong, Tj, Lee, Hw, Hyon, M, Jung, Jw, Jeon, Hk, Lee, Jm, Kang, Dh, Choi, Kj, Kim, Cj, Jin, E, Kim, D, Seo, J, Kim, H, Cha, Mj, Kim, Jt, Park, M, Kim, Jh, Park, Jh, Kim, J, Park, Sj, Kim, Sh, Seo, Jb, Kim, Yj, Chun, My, Lee, Mh, Joung, By, Lee, Sh, Shin, Dg, Namgung, J, Kwak, Jj, Rha, Sw, Na, Jo, Rim, Sj, Kim, Jy, Arcocha Torres, M, Rey, Am, Blanco Coronado, J, Puertas, I, Bruguera Cortada, J, Cabero, P, Calvo, C, Calvo, G, de Arce Borda, A, Asensio, A, Diez Tejedor, E, Guevara, Mp, Gonzalez Juanatey, J, Moure, M, Hernandez Madrid, A, Delgado, A, Lopez Garcia Aranda, V, Barquero, R, Manzano, L, Abril, Sb, Merino, J, Diaz Pintado, M, Arias, J, Fernandez, M, Alvarez, Rf, Terns, M, Delgado, Md, Villuendas, R, Astier, L, Appelros, P, Åkerberg, A, Blom, Kb, Andersson, R, Blomström, P, Persson, L, Carlsson, T, Bengtsson, A, Dettmann, S, Östberg, S, Engdahl, J, Karlsson, L, Herlitz, J, Winberg, L, Jernhed, H, Koskinen, P, Håkansson, E, Kozak, P, Edlund, M, Malmqvist, L, Eriksson, G, Randers, F, Moodh, J, Rautio, A, Johansson, M, Rönn, F, Sundholm, C, Stenberg, A, Gunnarsson, A, Thulin, J, Broberg, M, Slater, Ip, Cheng, Cc, Wu, W, Chiang, Ce, Yu, Wc, Chiang, Ft, Wu, Yw, Chiou, Cw, Yeh, Tc, Hsia, Ch, Chen, Yp, Huang, Jl, Chen, Yf, Kuo, Ct, Wang, Cl, Lai, Wt, Lin, Th, Lee, Jt, Pai, Py, Lin, Kh, Shyu, Kg, Chiu, Cz, Tseng, Wk, Pan, Yf, Ueng, Kc, Lee, Sc, Wang, Jh, Tsai, Wc, Yeh, Hi, Kuo, Jy, Jirasirirojanakorn, K, Pornchaiyasit, K, Kaewsuwanna, P, Sinthusopa, W, Kiatchoosakun, S, Sriprasert, S, Laothavorn, P, Bamrungpong, P, Piyayotai, D, Sripracha, A, Panpunuan, P, Sukonthasarn, A, Mekara, W, Vorasettakarnkij, Y, Puripun, E, Acikel, M, Akilli, H, Demir, H, Ata, N, Bayata, S, Cakmak, N, Calik, A, Cayli, M, Ceyhan, C, Erdogan, D, Ermis, C, Kabul, K, Kanadasi, M, Turgut, O, Tandogan, I, Yalcin, R, Yigit, F, Yigit, Z, Zoghi, M, Batushkin, V, Azhdari, M, Bazylevych, A, Vlasyuk, Z, Bereznyakov, I, Lebedynskaya, M, Dotsenko, S, Kulynych, R, Dzyak, G, Vasilyeva, L, Faynyk, A, Sorokivskyy, M, Gavrysyuk, V, Dzublik, Y, Horbach, L, Husyev, V, Godlevska, O, Samburg, Y, Karpenko, O, Nevolina, I, Karpenko, Y, Blihar, O, Kaydashev, I, Gerasimenko, N, Kolomyyits, S, Vasylets, V, Kopytsya, M, Petyunina, O, Kotseruba, V, Dvoieglazova, M, Koval, V, Ohirko, O, Koval', O, Kaplan, P, Kraiz, I, Usan, N, Kraydashenko, O, Stets, R, Kupnovytska, I, Kyyak, Y, Lizogub, V, Gorna, O, Malynovsky, Y, Fedotov, S, Ostrovska, L, Ushakova Sokolova, L, Dovgan, N, Potapenko, P, Nekrasa, A, Prokhorov, O, Leonidova, V, Rebrov, B, Gamachek, O, Rishko, M, Chendey, T, Rudyk, I, Shatilo, V, Ishchuk, V, Shcherbak, V, Goncharova, I, Shvetz, N, Zamlynskyy, M, Sirenko, Y, Stanislavchuk, M, Perebetiuk, L, Sychov, O, Lyzohub, S, Tseluyko, V, Kuznetsov, I, Tykhonova, S, Vakaliuk, I, Drapchak, I, Vatutin, M, Sklyanna, O, Vizir, V, Goncharov, O, Volkov, V, Serik, S, Yagensky, A, Nahrebetskyy, V, Yena, L, Mudruk, I, Zharinov, O, Logvinov, Y, Zhurba, S, Shandra, T, Aggarwal, R, Smith, S, Beeton, I, Dunn, S, Blagden, M, Price, R, Dougal, K, Chapman, O, Davies, D, Choy, A, Duff, J, Cohen, A, Wilmott, R, D'Costa, D, Douglas, H, Dickinson, D, Lie, F, Ramasamy, V, Lindsay, S, Atkinson, C, Linker, N, Finlayson, M, Lip, G, Brown, R, Maccallum, P, Ebano, P, Macleod, M, Mcghee, C, Marazzi, P, Jones, D, Maxwell, T, Isted, C, More, R, Helliwell, L, Moriarty, A, Mackin, A, Murdoch, D, Andrews, A, Newby, D, Flint, L, Pye, M, Wright, L, Avery, D, Young, G, Sopher, M, Kennard, S, Storey, R, Bridge, C, Turner, W, Walker, M, Venkataraman, A, Gilchrist, M, Watkin, R, Chung, A, Wright, A, Wright, J, Abi Mansour, P, Panella, M, Adams, K, Lohman, J, Adler, J, Barash, B, Adler, P, Reiling, S, Beck, P, Ahmad, A, Hussain, A, Ahmadpour, H, Lim, G, Akhter, F, Brubaker, S, Alexander, J, Genova Peeva, E, Aliyar, P, Godsey, W, Allison, J, Biscardi, R, Almquist, A, Macdonald, H, Alsheikh, T, Lane, B, Amin, K, Khetarpal, S, Amin, M, Persechino, F, York, T, Arnold, T, Shoaf, R, Arouni, A, Rasmussen, L, Attanti, S, Strickland, S, Aude, Y, Cobos, D, Awasty, V, Baldwin, E, Ayesu, K, Thompson, B, Baine, S, Batista, M, Baman, R, Campbell, G, Barber, M, Altonen, D, Barker, T, Faircloth, C, Barrington, P, Gordon, L, Bartkowiak, A, Benton, J, Beasley, R, Hoffman, T, Bedoya, R, Luis Valdes, M, Bedwell, N, Craig, M, Beinart, S, Swaim, D, Bensimhon, D, Garman, V, Berk, M, Ibarra, M, Bernard, J, Eldred, R, Bilal, B, Preston, S, Bilazarian, S, Langone, L, Bingham, S, Antonino, M, Block, T, Talbot Lawson, C, Blonder, R, Ensminger, E, Bloomberg, R, Bloomberg, K, Blue, B, Vernon, M, Borsheim, M, Hickenbotham, D, Bouchard, A, Wade, W, Bowden, W, Ziegler, K, Bradley, A, Terry, P, Brilakis, E, Frey, W, Brown, H, Triano, A, Bybee, K, Al Maliky, T, Cader, C, Morton, S, Canaday, D, Canosa, R, Hartranft, E, Caplan, J, Jameson, L, Carr, K, Phan, D, Chang, M, Hatfield, G, Charlat, M, Tamayo, M, Chaturvedi, S, Sawaya, K, Ciaramita, J, Bagby, J, Clapp, T, Clay, A, Mcclelland, M, Dutka, C, Cohen, R, Bossaers, J, Colan, D, Salpas, S, Cole, J, Fisher, M, Concha, M, Martinez, E, Corbett, B, Svadbik, L, Cossu, S, Mullinax, K, Cottiero, R, Masson, E, Cowan, L, Nelson, L, Curtis, B, Sarpola, N, Dang, N, Morgan, T, Daniels, S, Leka, G, Datta, S, Wulf, A, Dave, K, Dave, B, Davuluri, A, Ebreo, N, De Lemos, J, Debes, C, Dean, J, Warmack, D, Degarmo, R, Carey, J, Steward, A, Desire, A, Waters, L, Devenport, S, Briscoe, C, Dhar, S, Ucik, S, Digiovanna, M, Tisdale, L, Donovan, D, Rodriguez, L, Dotani, I, Olson, A, Drozdiak, R, Habibi, S, D'Souza, A, Cullen, T, Eade, J, Dunn, K, Eldadah, Z, Quick, R, Ellis, J, Cristaldi, J, Erenrich, N, Johnson, C, O'Brien, J, Ettinger, N, Shipp, A, Everhart, B, Desalle, D, Fahmy, R, Watkins, D, Feld, L, Tameron, A, Feldman, J, Tang, N, Felten, W, Prior, J, Fialkow, J, Calvo, M, Finkel, M, Shriver, D, Finkelstein, S, Fischell, T, Drew, B, Fishbein, G, Donahue, S, Flores, E, Slayton, C, Forman, S, Solis, A, Frais, M, Thrope, C, Franco, M, Gentry, P, French, W, Morales, C, Friedlander, I, Gaffney, M, Jones, J, Garb, J, Miranda, J, George, F, Valentine, H, Gerber, J, Hinchion, N, Gillespie, E, Keane Richmond, P, Gogia, H, Ewing, B, Goldscher, D, Latteri, J, Goldstein, M, Gowda, S, Rafala, E, Graham, S, Bonora, M, Griffin, S, Aull, L, Griffin, J, Goodman, V, Grossman, C, Davis, A, Grove, D, Mabe, K, Guarino, J, Gabela, W, Guarnieri, T, Guerrero, Foster, B, Guthrie, R, Felsman, D, Gvora, T, Mclean, R, Hack, T, Morelli, L, Hamroff, G, Bentivenga, L, Han, M, Cavanna, L, Harris, J, Bobade, M, Hearne, S, Krater, C, Heiman, M, Dandekar, U, Shah, D, Henderson, D, Millard, D, Henry, S, Harkins, V, Hermany, P, Batchell, K, Herrod, J, Miranda, D, Herson, S, Carey, G, Hinchman, D, Vieira, P, Hippert, R, Dutter, S, Hoekstra, J, Homan, J, Homayouni, A, Horton, K, Sloss, D, Hotchkiss, D, Turner, N, Houchin, V, Howard, V, Hays, D, Howard, L, Craft, D, Huang, P, Truva, C, Hunter, J, Battistelli, E, Hurst, P, Garza, M, Hussain, M, Tambawala, M, Ison, R, Butcher, S, Jardula, M, Andresen, T, Johnson, F, Phillips, T, Jones, R, Hughett, G, Jovin, I, Nichols, M, Judson, P, Royes, A, Kahn, B, Coombs, V, Kai, W, Dugal, J, Kandath, D, Kostedt, G, Kaplan, K, Cook, S, Kapoor, A, Ruggiero, M, Karunaratne, H, Behm, K, Kastelic, R, Davis, C, Keller, R, Keller, J, Kerkering, M, Bartholomaus, D, Kersh, R, Buhler, A, Kesselbrenner, M, Dicorcia, L, Khan, B, Binns, M, Khan, M, Khan, G, Kindman, L, Averett, P, Korpas, D, Godfrey, C, Kotha, P, Sanchez, E, Kozlowski, J, Watts, S, Krichmar, P, Marquez, D, Laliotis, A, Jauregui, V, Lambert, C, Coyle, G, Landau, C, Ferguson, D, Lang, J, Simmons, T, Langevin, E, Faucett, S, Ledbetter, L, Royse, H, Lentz, M, Smith, D, Lesser, M, Hartley, L, Lewis, D, Bonds, C, Lillestol, M, Miller, D, Ling, L, Murphy, R, Littlefield, R, Wofford, E, Lomnitz, D, Lone, B, Davids, M, Looby, R, Ault, S, Lui, H, Wright, H, Lurie, M, Edelstein, J, Macomber, J, Bush, D, Magee, A, Doctor, A, Mainigi, S, Lisiecki, B, Makam, S, Casas, R, Mandviwala, M, Marar, I, Rabadi Marar, D, Marenberg, M, Bedenko, E, Massin, E, Hicks, T, Mccartney, M, Stubbs, L, Mcgarvey, J, Schwarz, L, Mcguire, K, Mckenzie, M, Rodkey, K, Mcknight, T, Paul, J, Mclaurin, B, Lack, A, Mega, J, Marti, J, Meholick, A, Skinner, J, Mehrle, A, Wall, J, Mendelson, R, Cervellione, K, Mercado, A, Cajulis, C, Michlin, B, Romero Colon, J, Milas, J, Sanders, D, Miller, R, Sanchez, S, Miller, S, Gryczan, J, Mody, F, Strugatsky, S, Moran, J, Garner, S, Morledge, J, Bowman, B, Mouhaffel, A, Parrott, N, Mounsey, P, Schuler, C, Mowdy, M, Todd, S, Mullen, P, Raziano, S, Murphy, A, Oehmann, V, Nadar, V, Parker, A, Naidu, J, West, M, Nallasivan, M, Goza, J, Nguyen, T, Nomanee, S, Nielsen, R, Wilmot, M, Oberoi, M, Thakkar, N, Oppenheimer, K, Mccormick, J, Orchard, R, Garcia, L, Osborne, J, Gonzalez, M, Oza, S, Joseph, L, Patnam, S, Dennison, K, Pavon, H, Gorry, N, Pearlstein, R, Montayne, S, Pentz, W, Duncan, D, Peters, P, Chacon, L, Petruzziello, F, Morlando, F, Pettis, K, Brown, F, Pezzella, S, Kirk, D, Poulathas, A, Cush, S, Pratt, R, Neeper, L, Pribble, A, Lowe, K, Pudi, K, Sham, L, Pugeda, J, Ebert, J, Quadrel, M, Rafla, E, Quinlan, E, Reed, C, Quinn, J, Hemmen, C, Rama, P, Domingo, D, Redondo, V, Wroblewski, J, Renzi, M, Stanley, E, Richwine, R, Pazier, P, Riofrio, K, Braun, D, Robinson, J, Cherrico, M, Roehll, W, Hollihan, P, Rosado, Barnhorst, M, Rosado, J, Bamhorst, M, Rosen, R, Martin, C, Ross, S, Freeman, R, Ruoff, G, Nelson, T, Sacco, J, Ball, E, Samal, A, Schomburg, J, Sandberg, J, Lafave, J, Savin, V, Clifton, R, Schaefer, S, Fekete, A, Schneider, R, Schneider, W, Schulman, D, Mercer, S, Seals, A, Ullig, T, Holt, A, Seide, H, Mather, N, Shah, G, Witt, P, Shalaby, A, Seese, M, Shanes, J, Fleets, J, Shaoulian, E, Hren, A, Sheikh, K, Hengerer, T, Shih, H, Browning, J, Shoukfeh, M, Stephenson, L, Siler, T, Champagne, M, Simpson, P, Meyer, R, Singh, N, Turner, K, Singh, V, Nelson, M, Skierka, R, Hughes, B, Keene, R, Smith, R, Hodnett, P, Spangenthal, S, Thomason, L, Sperling, M, Vasquez, E, Spivack, E, Mccartney, P, Staniloae, C, Liu, M, Steljes, A, Cox, C, Struble, R, Vittitow, T, Suresh, D, Frost, J, Swerchowsky, V, Freemyer, D, Szulawski, I, Herwehe, S, Tahirkheli, N, Springer, K, Takata, T, Bruton, T, Talano, J, Leo, L, Tami, L, Corchado, D, Tatarko, M, Swauger, M, Tawney, K, Dastoli, K, Teague, S, Young, K, Tee, H, Mitchell, T, Teixeira, J, Southam, D, Torres, M, Tucker, P, Salas, L, Updegrove, J, Hanna, K, Val Mejias, J, Harrelson, Kg, Vemireddy, D, Cardoza, T, Verma, S, Parsons, T, Vicari, R, Warren, K, Vijay, N, Washam, M, Vossler, M, Kilcup, S, Walsh, R, Renaud, K, Ward, S, Locklear, T, Waxman, F, Sanchez, G, Weiss, R, St Laurent, B, Westcott, J, Williams, D, Gibson, C, Williams, R, Dowling, C, Willis, J, Vongerichten, S, Wood, K, Capasso Gulve, E, Worley, S, Pointer, S, Yarows, S, Sheehan, T, Yasin, M, Yi, J, Dongas, B, Yousuf, K, Zakhary, B, Curtis, S, Zeig, S, Mason, T, Zellner, C, Harden, M, Roper, E, Waseem, M, and Grammer, M.
- Subjects
Male ,Pyridines ,[SDV]Life Sciences [q-bio] ,Embolism ,Kaplan-Meier Estimate ,030204 cardiovascular system & hematology ,chemistry.chemical_compound ,0302 clinical medicine ,Edoxaban ,Atrial Fibrillation ,MESH: Double-Blind Method ,030212 general & internal medicine ,MESH: Warfarin ,Stroke ,MESH: Aged ,MESH: Middle Aged ,Cardiovascular diseases [NCEBP 14] ,Hazard ratio ,General Medicine ,MESH: Follow-Up Studies ,Middle Aged ,3. Good health ,MESH: Atrial Fibrillation ,Cardiovascular Diseases ,Anesthesia ,Cardiology ,Female ,Adult ,Aged ,Anticoagulants ,Double-Blind Method ,Follow-Up Studies ,Hemorrhage ,Humans ,Thiazoles ,Warfarin ,MESH: Hemorrhage ,Andexanet alfa ,medicine.drug ,medicine.medical_specialty ,MESH: Enoxaparin ,MESH: Anticoagulants ,MESH: Stroke ,Dabigatran ,03 medical and health sciences ,Internal medicine ,medicine ,MESH: Kaplan-Meier Estimate ,Rivaroxaban ,MESH: Humans ,business.industry ,MESH: Cardiovascular Diseases ,MESH: Adult ,medicine.disease ,Confidence interval ,MESH: Male ,chemistry ,business ,MESH: Female ,MESH: Embolism - Abstract
Contains fulltext : 125374.pdf (Publisher’s version ) (Open Access) BACKGROUND: Edoxaban is a direct oral factor Xa inhibitor with proven antithrombotic effects. The long-term efficacy and safety of edoxaban as compared with warfarin in patients with atrial fibrillation is not known. METHODS: We conducted a randomized, double-blind, double-dummy trial comparing two once-daily regimens of edoxaban with warfarin in 21,105 patients with moderate-to-high-risk atrial fibrillation (median follow-up, 2.8 years). The primary efficacy end point was stroke or systemic embolism. Each edoxaban regimen was tested for noninferiority to warfarin during the treatment period. The principal safety end point was major bleeding. RESULTS: The annualized rate of the primary end point during treatment was 1.50% with warfarin (median time in the therapeutic range, 68.4%), as compared with 1.18% with high-dose edoxaban (hazard ratio, 0.79; 97.5% confidence interval [CI], 0.63 to 0.99; P
- Published
- 2013
29. Impact of Spontaneous Extracranial Bleeding Events on Health State Utility in Patients with Atrial Fibrillation: Results from the ENGAGE AF‐TIMI 48 Trial
- Author
-
Senior, R., Paul, J., McKnight, T., Formoso, I., Saravia Toledo, S., Codutti, O., Sanjurjo, M., Bowen, L., Sanchez, A., Alvarez, M., Rodriguez, M., Navarrete, S., Ramos, H., Venturini, C., Prado, A., Fernandez, E., Pozzer, D., Casares, E., Povedano, G., Tommasi, A., Piskorz, D., Verdini, E., Nul, D., Gandur, H., Muntaner, J., Funes, I., Marino, J., Calderon, M., Manuale, O., Carne, M., Mackinnon, I., Raimondi, G., Lotti, J., Shatsky, K., Rodkey, K., Lorente, C., Vignau, S., Llanos, J., Nigro, A., Litvak, B., Iglesias, M., Liniado, G., Belcuore, M., Lanternier, G., Monaco, F., Kevorkian, R., Jure, D., Jure, H., Bianchini, M., Avery, D., Hominal, M., von Wulffen, M., McKenzie, M., Miranda, J., Wright, L., Pye, M., Flint, L., Newby, D., Andrews, A., Goicoechea, R., Huerta, M., Giannaula, R., Eden, M., Giacomi, G., Ceirano, C., Garrido, M., Perlo, D., Garcia Duran, R., Meiller, F., Gant Lopez, J., Zanotti, A., Fuselli, J., Arrieta, M., Femenia, F., Falu, E., Facello, M., Facello, A., Murdoch, D., Helliwell, L., More, R., Isted, C., Maxwell, T., Jones, D., Marazzi, P., McGhee, C., MacLeod, M., Ebano, P., MacCallum, P., Davolos, M., Estol, C., Moreno, V., Dran, R., Cendali, G., D'Amico, A., Bocanera, M., Cuneo, C., Rosell, M., Cuello, J., Morandini, M., Colombo, H., Brown, R., Saa Zarandon, R., Caruso, O., Novas, V., Cartasegna, L., Fracaro, V., Caccavo, A., Saravia, M., Bustamante Labarta, G., Valle, M., Budassi, N., Lip, G., Finlayson, M., Linker, N., McGuire, K., Atkinson, C., Lindsay, S., Ramasamy, V., Lie, F., Dickinson, D., Douglas, H., D'Costa, D., Wilmott, R., Cohen, A., Duff, J., Choy, A., Davies, D., Chapman, O., Dougal, K., Camm, J., Price, R., Blagden, M., Schwarz, L., McGarvey, J., Stubbs, L., McCartney, M., Hicks, T., Massin, E., Bedenko, E., Marenberg, M., Rabadi-Marar, D., Dunn, S., Beeton, I., Smith, S., Aggarwal, R., Marar, I., Hernandez, S., Berli, M., Petrucci, J., Beloscar, J., Caceres, M., Amuchastegui, M., Ameriso, P., Ameriso, S., Garcia, M., Alvarez, C., Reguero, M., Allall, O., Rosales, E., Albisu, J., Ahuad Guerrero, R., Gonzalez, C., Vogelmann, O., Magnuson, Elizabeth A., Cohen, David J., Giugliano, Robert P., Mandviwala, M., Casas, R., Makam, S., Lisiecki, B., Mainigi, S., Doctor, A., Magee, A., Bush, D., Macomber, J., Edelstein, J., Lurie, M., Wright, H., Lui, H., Ault, S., Looby, R., Davids, M., Lone, B., Shah, D., Lomnitz, D., Wofford, E., Littlefield, R., Murphy, R., Ling, L., Miller, D., Lillestol, M., Bonds, C., Lewis, D., Hartley, L., Lesser, M., Smith, D., Lentz, M., Royse, H., Ledbetter, L., Faucett, S., Langevin, E., Simmons, T., Lang, J., Ferguson, D., Landau, C., Coyle, G. Stagi, Lambert, C., Jauregui, V., Laliotis, A., Marquez, D., Krichmar, P., Watts, S., Kozlowski, J., Sanchez, E., Kotha, P., Godfrey, C., Korpas, D., Averett, P., Kindman, L., Khan, G., Khan, M., Binns, M., Khan, B., DiCorcia, L., Kesselbrenner, M., Buhler, A., Kersh, R., Bartholomaus, D., Kerkering, M., Keller, J., Keller, R., Davis, C., Kastelic, R., Behm, K., Karunaratne, H., Ruggiero, M., Kapoor, A., Cook, S., Kaplan, K., Kostedt, G., Kandath, D., Dugal, J., Kai, W., Coombs, V., Kahn, B., Royes, A., Judson, P., Nichols, M., Jovin, I., Hughett, G., Jones, R., Phillips, T., Johnson, F., Andresen, T., Jardula, M., Butcher, S., Ison, R., Tambawala, M., Hussain, M., Garza, M., Hurst, P., Battistelli, E., Hunter, J., Truva, C., Huang, P., Craft, D., Howard, L., Hays, D., Howard, V., Adams, K., Houchin, V., Turner, N., Hotchkiss, D., Sloss, D., Horton, K., Homayouni, A., Homan, J., Young, C., Hoekstra, J., Dutter, S., Hippert, R., Vieira, P., Hinchman, D., Carey, G., Herson, S., Miranda, D., Herrod, J., Batchell, K., Hermany, P., Harkins, V., Henry, S., Millard, D., Henderson, D., Dandekar, U., Heiman, M., Krater, C., Hearne, S., Bobade, M., Harris, J., Cavanna, L., Han, M., Bentivenga, L., Hamroff, G., Morelli, L., Hack, T., McLean, R., Gvora, T., Felsman, D., Guthrie, R., Foster, B., Guerrero, Guerrero, Fisher, M., Guarnieri, T., Gabela, W., Guarino, J., Mabe, K., Grove, D., Davis, A., Grossman, C., Goodman, V., Griffin, J., Aull, L., Griffin, S., Bonora, M., Graham, S., Rafala, E., Gowda, S., Goldstein, M., Latteri, J., Goldscher, D., Ewing, B., Gogia, H., Keane-Richmond, P., Gillespie, E., Hinchion, N., Gerber, J., Valentine, H., George, F., Garb, J., Jones, J., Gaffney, M., Smith, K., Friedlander, I., Morales, C., French, W., Gentry, P., Franco, M., Thrope, C., Frais, M., Solis, A., Forman, S., Slayton, C., Flores, E., Donahue, S., Fishbein, G., Drew, B., Fischell, T., Lim, G., Finkelstein, S., Shriver, D., Finkel, M., Calvo, M., Fialkow, J., Prior, J., Felten, W., Tang, N., Feldman, J., Tameron, A., Feld, L., Watkins, D., Fahmy, R., DeSalle, D., Everhart, B., Shipp, A., Ettinger, N., O'Brien, J., Johnson, C., Erenrich, N., Cristaldi, J., Ellis, J., Quick, R., Eldadah, Z., Dunn, K., Eade, J., Cullen, T., D'Souza, A., Habibi, S., Drozdiak, R., Olson, A., Dotani, I., Rodriguez, L., Donovan, D., Tisdale, L., DiGiovanna, M., Ucik, S., Dhar, S., Briscoe, C., Devenport, S., Waters, L., Desire, A., Steward, A., Desai, A., Carey, J., DeGarmo, R., Warmack, D., Dean, J., Debes, C., De Lemos, J., Ebreo, N., Davuluri, A., Dave, B., Dave, K., Wulf, A., Datta, S., Leka, G., Daniels, S., Morgan, T., Dang, N., Sarpola, N., Curtis, B., Nelson, L., Cowan, L., Masson, E., Cottiero, R., Mullinax, K., Cossu, S., Svadbik, L., Corbett, B., Martinez, E., Concha, M., Cole, J., Salpas, S., Colan, D., Bossaers, J., Cohen, R., Dutka, C., McClelland, M., Clay, A., Clapp, T., Bagby, J., Ciaramita, J., Sawaya, K., Chaturvedi, S., Tamayo, M., Charlat, M., Hatfield, G., Chang, M., Phan, D., Carr, K., Jameson, L., Caplan, J., Hartranft, E., Canosa, R., Canaday, D., Morton, S., Cader, C., Al-Maliky, T., Bybee, K., Triano, A., Brown, H., Frey, W., Brilakis, E., Terry, P., Bradley, A., Ziegler, K., Bowden, W., Wade, W., Bouchard, A., Hickenbotham, D., Borsheim, M., Vernon, M., Blue, B., Bloomberg, K., Bloomberg, R., Ensminger, E., Blonder, R., Talbot-Lawson, C., Block, T., Antonino, M., Bingham, S., Langone, L., Bilazarian, S., Preston, S., Bilal, B., Eldred, R., Bernard, J., Ibarra, M., Berk, M., Garman, V., Bensimhon, D., Swaim, D., Beinart, S., Craig, M., Bedwell, N., Luis-Valdes, M., Bedoya, R., Hoffman, T., Beasley, R., Benton, J., Bartkowiak, A., Gordon, L., Barrington, P., Faircloth, C., Barker, T., Altonen, D., Barber, M., Campbell, G., Baman, R., Batista, M., Baine, S., Thompson, B., Ayesu, K., Baldwin, E., Awasty, V., Cobos, D., Aude, Y., Strickland, S., Attanti, S., Rasmussen, L., Arouni, A., Shoaf, R., Arnold, T., York, T., Anderson, J., Persechino, F., Amin, M., Khetarpal, S., Amin, K., Lane, B., Alsheikh, T., MacDonald, H., Almquist, A., Biscardi, R., Allison, J., Godsey, W., Aliyar, P., Genova-Peeva, E., Alexander, J., Brubaker, S., Akhter, F., Ahmadpour, H., Hussain, A., Ahmad, A., Beck, P., Reiling, S., Adler, P., Barash, B., Adler, J., Lohman, J., Panella, M., Abi-Mansour, P., Roberts, J., Mackin, A., Moriarty, A., Green, M., Shandra, T., Zhurba, S., Logvinov, Y., Zharinov, O., Mudruk, I., Yena, L., Nahrebetskyy, V., Yagensky, A., Serik, S., Volkov, V., Goncharov, O., Vizir, V., Sklyanna, O., Vatutin, M., Drapchak, I., Vakaliuk, I., Tykhonova, S., Kuznetsov, I., Tseluyko, V., Lyzohub, S., Sychov, O., Perebetiuk, L., Stanislavchuk, M., Sirenko, Y., Zamlynskyy, M., Shvetz, N., Goncharova, I., Shcherbak, V., Ishchuk, V., Shatilo, V., Rudyk, I., Chendey, T., Rishko, M., Gamachek, O., Rebrov, B., Leonidova, V., Prokhorov, O., Nekrasa, A., Potapenko, P., Dovgan, N., Parkhomenko, A., Ushakova-Sokolova, L., Ostrovska, L., Fedotov, S., Malynovsky, Y., Gorna, O., Lizogub, V., Kyyak, Y., Kupnovytska, I., Stets, R., Kraydashenko, O., Usan, N., Kraiz, I., Kaplan, P., Koval', O., Ohirko, O., Koval, V., Dvoieglazova, M., Kotseruba, V., Petyunina, O., Kopytsya, M., Vasylets, V., Kolomyyits, S., Gerasimenko, N., Kaydashev, I., Blihar, O., Karpenko, Y., Nevolina, I., Karpenko, O., Samburg, Y., Godlevska, O., Husyev, V., Horbach, L., Dzublik, Y., Gavrysyuk, V., Sorokivskyy, M., Faynyk, A., Vasilyeva, L., Dzyak, G., Kulynych, R., Dotsenko, S., Lebedynskaya, M., Bereznyakov, I., Vlasyuk, Z., Bazylevych, A., Azhdari, M., Batushkin, V., Zoghi, M., Yigit, Z., Yigit, F., Tandogan, I., Turgut, O., Oto, A., Kanadasi, M., Kabul, K., Ermis, C., Erdogan, D., Ceyhan, C., Cayli, M., Calik, A., Cakmak, N., Bayata, S., Ata, N., Demir, H., Akilli, H., Acikel, M., Puripun, E., Vorasettakarnkij, Y., Mekara, W., Sukonthasarn, A., Panpunuan, P., Sritara, P., Sripracha, A., Piyayotai, D., Bamrungpong, P., Laothavorn, P., Sriprasert, S., Kiatchoosakun, S., Sinthusopa, W., Kaewsuwanna, P., Pornchaiyasit, K., Jirasirirojanakorn, K., Kuo, J. Y., Yeh, H. I., Tsai, W. C., Lee, S. C., Ueng, K. C., Pan, Y. F., Tseng, W. K., Chiu, C. Z., Shyu, K. G., Lin, K. H., Pai, P. Y., Lee, J. T., Lin, T. H., Lai, W. T., Wang, C. L., Kuo, C. T., Chen, Y. F., Huang, J. L., Chen, Y. P., Hsia, C. H., Yeh, T. C., Chiou, C. W., Wu, Y. W., Chiang, F. T., Yu, W. C., Chiang, C. E., Wu, W. S., Cheng, C. C., Slater, I. Petrova, Moccetti, T., Broberg, M., Thulin, J., Gunnarsson, A., Stenberg, A., Sundholm, C., Ronn, F., Johansson, M., Rautio, A., Moodh, J., Randers, F., Eriksson, G., Malmqvist, L., Edlund, M., Kozak, P., Hakansson, E., Koskinen, P., Jernhed, H., Juul-Moller, S., Winberg, L., Herlitz, J., Karlsson, L., Engdahl, J., Ostberg, S., Dettmann, S., Bengtsson, A. Stener, Carlsson, T., Persson, L., Blomstrom, P., Andersson, R., Blom, K. Berndtsson, Akerberg, A., Appelros, P., Astier, L., Villuendas, R., Dachs Delgado, M., Terns, M., Fernandez Alvarez, R., Fernandez, M., Arias, J., Diaz-Pintado, M., Merino, J., Blanco Abril, S., Manzano, L., Barquero, R., Lopez Garcia-Aranda, V., Delgado, A., Hernandez Madrid, A., Moure, M., Gonzalez Juanatey, J., Perez Guevara, M., Diez Tejedor, E., Asensio, A., De Arce Borda, A., Calvo, G., Calvo, C., Cabero, P., Bruguera Cortada, J., Puertas, I., Blanco Coronado, J., Manzanal Rey, A., Arcocha Torres, M., Kim, J. Y., Rim, S. J., Na, J. O., Rha, S. W., Kwak, J. J., Namgung, J., Shin, D. G., Lee, S. H., Joung, B. Y., Lee, M. H., Chun, M. Y., Kim, Y. J., Seo, J. B., Kim, S. H., Park, S. J., Kim, J. S., Park, J. H., Kim, J. H., Park, M. S., Kim, J. T., Cha, M. J., Kim, H. S., Seo, J. S., Kim, D. S., Jin, E. S., Kim, C. J., Choi, K. J., Kang, D. H., Lee, J. M., Jeon, H. K., Jung, J. W., Hyon, M. S., Lee, H. W., Hong, T. J., Lee, K. H., Han, S. H., Oh, Y. S., Chung, W. S., Hong, K. S., Choi, H. H., Ryu, D. R., Cho, B. R., Kim, D. H., Cha, J. K., Han, M. G., Bae, H. J., Wessels, L., Venter, T., Le Roux, M., Van Zyl, L., Goosen, Y., Van Der Merwe, N., Johnston, H., Soma, P., Munnik, M., Snyders, F., Duki, Y., Naidoo, D., Taljaard, J., Mitha, I., Kelfkens, Y., Wilson, L., Gani, M., Nunkoo, T., Essop, M., Mostert, M., Engelbrecht, J., Botha, L., Ellis, G., Allman, J., Dalby, A., Poynton, M., Basson, M., Erasmus, L., Badenhorst, J., Bollova, D., Zareczky, P., Kokles, M., Zachar, A., Kmec, J., Slanina, M., Morsky, J., Ruffini, L., Fedacko, J., Pella, D., Mazur, J., Reptova, A., Kasperova, V., Hofmanova, J., Hranai, M., Hatala, R., Hatalova, K., Dzupinova, M., Dzupina, A., Vankova, L., Duris, T., Dulka, T., Dulkova, K., Kosmalova, V., Dukat, A., Banikova, A., Ambrovic, I., Ambrovicova, V., Tesic, M., Golshmid, M., Ruda, M., Topolnitchi, O., Castro, C., Ostojic, M., Tesic, B. Vujisic, Mitrovic, P., Vasiljevic-Pokrajcic, Z., Davicevic, Z., Tavciovski, D., Milinkovic, I., Seferovic, P., Kalezic, T., Putnikovic, B., Polovina, M., Potpara, T., Tasic, N., Otasevic, P., Djokic, I., Miloradovic, V., Djokovic, A., Krotin, M., Ilic, B., Ilic, S., Erceg, P., Despotovic, N., Bjelobrk, M., Adjic, N. Cemerlic, Majstorovic, A., Celic, V., Djordjevic-Radojkovic, D., Apostolovic, S., Motylev, I., Zubeeva, G., Kononenko, O., Zenin, S., Mankhaeva, B., Zateyshchikova, A., Zotova, I., Zateyshchikov, D., Nikulina, N., Yakushin, S., Petrochenko, A., Yakusevich, V., Rodina, N., Volkov, D., Kirgizova, A., Vishnevsky, A., Rossovskaya, M., Ustyugov, S., Bulygin, S., Timofeev, A., Solovyev, A., Tikhonova, E., Kositsyna, I., Tereshenko, S., Isakov, L., Tarasov, N., Dronov, D., Suprun, E., Erofeeva, S., Sobolev, K., Lapidus, N., Sizova, Z., Orlov, V., Sinitsina, I., Vorontsova, S., Sidorenko, B., Agirov, M., Shogenov, Z., Lebedev, E., Shaposhnik, I., Repin, M., Karoli, N., Rebrov, A., Letaeva, M., Raskina, T., Pikalova, N., Poluyanova, N., Matveeva, I., Polkanova, E., Nilk, R., Panov, A., Laguta, P., Panchenko, E., Patrusheva, S., Novikova, N., Khromova, O., Nikolskaya, I., Nikolaev, A., Nikolaev, K., Lamden, D., Lukyanov, Y., Belousova, L., Lila, A., Moiseeva, Y., Libov, I., Maslova, A., Libis, R., Volkova, E., Levashov, S., Tereschenko, L., Lavrova, O., Rychkov, A., Kuznetsov, V., Kostenko, O., Kozyrev, O., Polyanskaya, E., Koziolova, N., Karabalieva, S., Kostenko, V., Khrustalev, A., Khrustalev, O., Tsareva, E., Khokhlov, R., Sinitsina, O., Khokhlov, A., Kireenkov, I., Khirmanov, V., Kosenko, B., Buza, V., Karpov, Y., Mazovets, O., Gratsiansky, N., Laptev, I., Goloshchekin, B., Kratskina, T., Golitsyn, S., Valovyeva, S., Glezer, M., Valuyshkih, E., Gilinskaya, O., Soin, I., Filatov, A., Kirichek, N., Esip, V., Egorova, L., Zyatenkova, E., Drapkina, O., Puchinyan, N., Dovgalevsky, P., Masin, A., Demko, A., Pokutneva, O., Chumakova, G., Khlevchuk, T., Bokarev, I., Yukhno, E., Berns, S., Kosolapov, Y., Belenky, D., Larina, V., Bart, B., Bashkireva, A., Barbarash, O., Alexandrova, L., Ballyuzek, M., Chernyavskaya, T., Arutyunov, G., Zhukova, N., Tudoran, C., Tudoran, M., Topolnitchi, L., Spinu, C., Stamate, S., Plosca, P., Sipciu, D., Ardelean, A., Popescu, M., Cozma, M., Pop, C., Serban, D., Minescu, B., Costache, L., Iosipescu, L., Jurca, S., Dragomir, D., Sirbu, I., Dobreanu, D., Voicu, O., Dobre, I., Jemna, D., Crisu, D., Anciu, M., Cristea, M., Parasteac, M., Creteanu, M., Constantinescu, M., Ghionea, M., Coman, I., Andor, M., Ciobotaru, G., Bolohan, F., Doka, B., Bobescu, E., Ochean, V., Bengus, C., Badila, E., Bartos, D., Matei, C., Apetrei, E., Ciortea, M., Albulescu, P., Soares, D., Santos, J., Veiga Pais Nunes, L., Santos, O., Goncalves, A., Salgado, A., Leitao Marques, A., Oliveira, D., Monteiro, P., Neves, E., Martins, D., Maymone, D., Madeira, J., Lopes, S., Gil, V., Correia, J., Matias, F., Nawrot, M., Zielinski, M., Krauze, R., Zarebinski, M., Kudlicki, J., Wysokinski, A., Muzalewski, P., Wrobel, W., Turbak, R., Malanska, A., Szolkiewicz, M., Spyra, J., Sendrowski, D., Norwa-Otto, B., Ruzyllo, W., Ronkowski, R., Rozmyslowicz-Szerminska, W., Rewinska, H., Zienciuk-Krajka, A., Raczak, G., Bojanowska, E., Polaszewska-Pulkownik, V., Pogorzelska, H., Janczewska, D., Podjacka, D., Olszewski, M., Nowak, J., Nej, A., Niezgoda, K., Nessler, B., Nessler, J., Biniek, D., Napora, P., Myslinski, W., Mosiewicz, J., Kosmalska, K., Miekus, P., Chmielowski, A., Mazur, S., Kosmaczewska, A., Wnetrzak-Michalska, R., Sznajder, R., Matyszczak-Toniak, L., Jaguszewska, G., Lysek, R., Szymanska, K., Lubinski, A., Stopyra-Poczatek, M., Lewczuk, J., Wierzykowski, T., Lesnik, J., Kus, W., Sklodowskiej-Curie, M., Muzyk-Osikowicz, M., Krzyzanowski, W., Borowski, W., Korzeniak, R., Benicka, E., Konieczny, M., Kaliszczak, R., Karczmarczyk, A., Tymendorf, K., Kania, G., Kaminski, L., Pacholska, A., Kaczmarek, B., Jurowiecki, J., Ciezak, P., Jazwinska-Tarnawska, E., Makowiecka-Ciesla, M., Januszewicz, A., Mroczkowski, P., Gniot, J., Zajac, E., Gieroba, A., Guziewicz, M., Domanska, E., Laskowska-Derlaga, E., Derlaga, B., Ptak, A., Dabrowska, M., Cymerman, K., Krzystolik, A., Busz-Papiez, B., Cieslak, B., Bronisz, M., Baszak, J., Korzeniowska-Adamus, J., Adamus, J., Nario, K., Villamor, L., Aquino, M., To, R., Gilo, L., Roxas, A., Joaquin, F., Rogelio, G., Enad, C., Matiga, G., Vallenas, M., Coching, R., Zapanta, M., Barcinas, R., Sambaz, C. M., Babilonia, N., Delgado, S., Horna, M., Yanac Chavez, P., Fernandez Rodriguez, K., Torres, P., Romero, N., Rodriguez, A., Honores Armas, B., Negron Miguel, S., Bautista, C., Minchola, J., Rodriguez, J., Medina Palomino, F., Araoz Bedregal, S., Llerena, N., Carrion, A., Lema, J., Luna, C., Chavez, C., Esteves Mendoza, R., Cabrera, J., Tejada Guillen, M., Bustamante, G., Enger, S., Tveit, A., Thunhaug, H., Sandvik, J., Melbue, R., Hofsoy, K., Claussen, H., Atar, D., Kennett, K., Skelton, L., Troughton, R., Cammell, R., Scott, D., Turner, A., Hart, H., Tomlinson, J., Hamer, A., Green, B., Monkley, R., Fisher, R., Copley, M., Doughty, R., Borthwick, L., White, H., Benatar, J., Kjentjes, M., O'Meeghan, T., Anscombe, R., Hofmeyer, H., van der Heijden, D., Mevissen, H., Kooiman, E., Mannaerts, H., Muijs, L., Kietselaer, B., Daniels, R., Hazeleger, R., de Vos, R., Radder, I., de Groot, J., Buiks, C., Jones, A., Bruning, T., van Welsen, I., Alhakim, M., Moran Velazquez, E., Velasco Sanchez, R., Ortiz, A., Sanchez Diaz, C., Magallanes, G., Nevarez Ruiz, L., Avila, H., Mendez-Machado, G., Grajales, A., Llamas Esperon, G., de la Mora, S., Leiva-Pons, J., Jaramillo, A., Garcia-Castillo, A., Alcantara Colin, M., Garcia, N., Franco Valles, J., Casares Ramirez, M., Delgadillo, T., Carrillo, J., Cardona Munoz, E., Cedano Limon, M., Calvo Vargas, C., Hurtado, A., Bayram Llamas, E., Fujiwara, Y., Yoshioka, K., Nomura, H., Yoshino, H., Tanaka, K., Yonehara, T., Matsuda, K., Yamashita, T., Takiguchi, M., Yamashina, A., Ito, Y., Yamamoto, Y., Sasaki, S., Yamagishi, T., Yamano, R., Yamada, T., Sakamoto, Y., Yamabe, H., Kuroda, T., Yagi, H., Sato, A., Yagi, M., Sakai, Y., Usuda, K., Onishi, M., Ueyama, Y., Yasumoto, S., Uematsu, M., Terakura, K., Tsuboi, N., Yoshida, K., Tsuboi, H., Nishiya, Y., Tanouchi, J., Uchida, M., Watanabe, E., Takeuchi, S., Yamagishi, K., Takenaka, T., Yahata, A., Takeda, K., Sakurai, Y., Takahashi, T., Kishi, N., Takahashi, A., Takahashi, W., Mohri, S., Takagi, M., Asakura, H., Sumii, K., Miyazaki, E., Sugi, K., Ueda, J., Shoji, Y., Shigenari, M., Shirai, T., Narumi, M., Seino, Y., Fujimoto, E., Satoh, A., Oosawa, N., Sasaki, T., Ooki, H., Sakurai, S., Hayashi, N., Sakuragi, S., Nakano, A., Sakagami, S., Tanikawa, I., Ozaki, Y., Moriyama, H., Onaka, H., Narita, Y., Okumura, K., Kitani, S., Okishige, K., Wada, H., Okazaki, O., Nakashima, M., Okajima, K., Moriyama, Y., Okada, K., Tanabe, M., Oguro, H., Sugeno, M., Ogawa, T., Junko, H., Ochiai, J., Nagase, T., Nishi, Y., Oyama, H., Naito, S., Sakata, Y., Nagai, Y., Murata, J., Munemasa, M., Sakamoto, S., Miyauchi, Y., Kimizu, T., Miyamoto, N., Takeda, M., Mita, T., Satake, M., Meno, H., Ebina, E., Kaneno, Y., Masuyama, T., Koya, E., Kurabayashi, M., Yumoto, I., Koretsune, Y., Tamura, S., Kohno, M., Kikuchi, R., Kobayashi, Y., Igarashi, C., Kitazawa, H., Ichikawa, Y., Kazatani, Y., Ishida, A., Kato, K., Fujii, R., Kamiyama, K., Iida, S., Kamijo, M., Nakahara, F., Kamakura, S., Adachi, C., Kakinoki, S., Nagatome, H., Iwasaki, T., Sakuma, Y., Iwade, K., Ito, T., Itamoto, K., Ise, M., Ishimaru, S., Tomita, H., Ishii, Y., Nozaki, T., Ishibashi, Y., Nakamura, K., Inomata, T., Noguchi, H., Ino, H., Higuchi, K., Iijima, T., Miyamoto, C., Iesaka, Y., Kawaguchi, A., Hirayama, A., Nakagawa, Y., Higashikata, T., Oga, Y., Hiasa, Y., Shimazu, Y., Hashimoto, Y., Nakahara, Y., Haruna, T., Fuki, Y., Harada, K., Kumagai, S., Hara, S., Naganuma, M., Hagiwara, N., Kamitake, C., Furukawa, Y., Yamaguchi, A., Funazaki, T., Fujimoto, C., Fukuda, N., Harada, J., Fukamizu, S., Fujita, T., Ichishita, Y., Fujimoto, K., Omae, K., Fujimoto, S., Kotera, M., Fujii, E., Kozeni, S., Fujii, K., Fujiwara, M., Endo, H., Tsukimine, A., Arakawa, S., Mino, K., Anzai, T., Matsushita, C., Ajioka, M., Masaki, W., Akihisa, U., Hirahara, T., Furiozzi, F., Zaca, V., Gagliano, M., Toschi, V., Breschi, M., Severi, S., Cannoni, S., Rasura, M., Granzow, K., Raisaro, A., Fenu, L., Piseddu, G., Paradiso, G., Pirelli, S., Marciano, C., Filardi, P. Perrone, Lioy, E., Penco, M., Bulgari, M., Metra, M., Babbolin, M., Merlini, P., Francalacci, G., Marino, P., Raggi, F., Lo Pinto, G., Gaggioli, G., Laffi, Laffi, Murena, E., Grassia, V., Bosco, B., Fattore, L., Di Niro, M., Di Pasquale, G., Mazzone, C., Di Lenarda, A., Mariani, M., De Servi, S., De Pace, D., De Caterina, R., Forgione, C., Cuccia, C., Peruzzotti, L., Comi, G., Cervi, E., Boriani, G., Giovannelli, F., Berni, A., Platner, N., Zeltser, D., Kisos, D., Tsalihin, D., Belatsky, V., Swissa, M., Aloni, I., Shochat, M., Sterlin, J., Schiff, E., Logvinenko, S., Rozenman, Y., Givoni, H., Ouzan, E., Karny, M., Lishner, M., Ben Ari, M., Lewis, B., Genin, I., Klainman, E., Majdoub, A., Hayek, T., VonGerichten, S., Roshrosh, M., Hasin, Y., Dagan, T., Grossman, E., Rouwaida, S., Gottlieb, S., Goldhaber, M., Wood, K., Goldhaber, A., Capasso-Gulve, E., Worley, S., Willis, J., Dowling, C., Williams, R., Gibson, C., Williams, D., Pointer, S., Yarows, S., Sheehan, T., Ghantous, R., Francis, A., Ron, G. Avraham, Elias, M., Gilat, T., Lahav, M., Yasin, M., Marcoviciu, D., Dicker, D., Lasri, E., Atar, S., Dharmarao, A., Zanwar, I., Thakur, B., Vinod, M. Vijan, Yi, J., Dongas, B., Westcott, J., St Laurent, B., Yousuf, K., Weiss, R., Sanchez, G., Kaur, A., Varma, S., Thankaraj, L., Srinivas, A., Gupta, R., Singh, G., Sudheer, R., Shetty, G., Waxman, F., Locklear, T., Ward, S., Renaud, K., Sethia, S., Sethia, A., Bansal, N., Walsh, R., Kilcup, S., Vossler, M., Washam, M., Vijay, N., Warren, K., Sethi, K., Singh, R., Sawhney, J., Arora, T., Sarna, M., Jadhav, D., Sant, H., Gadepalli, R., Saha, D., Barai, A., Roy, D., Bekal, S., Reddy, R., Shankar, A. Ravi, Zakhary, B., Vuriya, A., Rao, M., Jambula, H., Premchand, R., Kharalkar, H., Pinto, B., Curtis, S., Zeig, S., Mason, T., Zellner, C., Babbar, A., Patki, N., Jasani, B., Vicari, R., Parekh, P., Harden, M., Sababathi, R., Pandurangi, U., Shams, S., Purayil, M. Padinhare, Angel, J., Gurusamy, P., Oomaan, A., Natarajan, S., Narendra, J., Shelke, S., Namjoshi, D., Francis, V., Menon, J., Sharma, P., Mathur, A., Roper, E., Waseem, M., Bhaskarwar, P., Mardikar, H., Kale, M., Grammer, M., Lavhe, P., Anthony, A., Kumbla, M., Francis, J., Kumar, A., Parsons, T., Karpuram, M., Kumar, P., Lawande, A., Kulkarni, G., Deokar, M., Verma, S., Cardoza, T., Vemireddy, D., Kulkarni, R., Kotiwale, V., Krishnan, H., Kishore, R., Kandekar, S., Kandekar, B., Raut, N., Kale, V., Joshi, H., Thomas, R., Joseph, J., Oommen, D., Joseph, S., Pahuja, M., Jain, R., Ghume, A., Hiremath, J., Thakor, G., Hardas, S., Savanth, P., Hadan, S., Singh, P., Gupta, J., Saini, A., Goyal, N., Mali, N., Chopda, M., Karnwal, N., Somaraju, B., Calambur, N., Bhuti, M., Biniwale, A., Rathi, A., Bhargava, V., Solanki, R., Bharani, A., Surushe, S., Benjarge, P., Sheth, T., Banker, D., Reddy, J., Babu, R., Rao, B., Babu, P., Shaikh, A., Avvaru, G., Shree, R., Arora, V., Memon, A., Arneja, J., Ranka, R., Agarwal, D., Abdullakutty, J., Malhan, S., Kincses, M., Vertes, A., Marosi, A., Tomcsanyi, J., Szakal, I., Sipos, T., Ruzsa, D., Simor, T., Bognar, A., Sayour, A., Toth, S. Rostasne, Palinkas, A., Nagy, A., Kolumban, E., Merkely, B., Kiss, K., Medvegy, M., Kiss, T., Matoltsy, A., Karakai, H. Horvathne, Lupkovics, G., Kovacs, Z., Baranyai, M., Kovacs, I., Koczka, M., Jakal, A., Kiss, R., Feil, J. Felfoldine, Kis, E., Kosztyu, M., Kanakaridisz, N., Varga, A., Harrelson, K. Gonzalez, Fiok, J., Szatmari, J., Edes, I., Muskoczki, E., Dioszeghy, P., Almaraz, S. Padilla, Camas, L. Velasquez, Guerra, L., Samayoa, C. Sanchez, Pozuelos, J. Mayen, Sanchez, M., Estrada, M. Rodas, Guevara, S., Lavagnino, A. Ovando, Jimenez, T., Melgar, I. Guzman, Ramirez, V. de Leon, Milla, O. Ayau, Korantanis, K., Pyrgakis, V., Kartsagkoulis, E., Olympios, C., Dimitra, K., Moschos, N., Daskalaki, A., Kifnidis, K., Exarchou, E., Karamitsos, C., Tziortziotis, A., Bourlios, P., Mavronasiou, E., Alexopoulos, D., Winter, K., Wolde, C., Buelow-Johansen, B., Winkelmann, B., Val-Mejias, J., Weyland, K., Buchholz, M., Voehringer, Voehringer, Ludwig, I., Veltkamp, R., Zarpentin, C., Taggeselle, J., Stoehring, R., Bonin, K., Spitzer, S., Baylacher, M., Sohn, H., Gold, G., Seibert, H., Hellmers, J., Schreckenberg, A., Schmidt, M., Schmidt, A., Hanna, K., Updegrove, J., Salas, L., Tucker, P., Torres, M., Southam, D., Teixeira, J., Mitchell, T., Tee, H., Young, K., Teague, S., Dastoli, K., Tawney, K., Swauger, M., Tatarko, M., Corchado, D., Tami, L., Leo, L., Talano, J., Bruton, T., Takata, T., Springer, K., Tahirkheli, N., Herwehe, S., Szulawski, I., Freemyer, D., Swerchowsky, V., Frost, J., Suresh, D., Vittitow, T., Struble, R., Cox, C., Steljes, A., Liu, M., Staniloae, C., McCartney, P., Spivack, E., Vasquez, E., Sperling, M., Thomason, L., Spangenthal, S., Hodnett, P., Smith, R., Keene, R., Hughes, B., Skierka, R., Nelson, M., Singh, V., Turner, K., Singh, N., Meyer, R., Simpson, P., Champagne, M., Schiewe, C., Siler, T., Stephenson, L., Shoukfeh, M., Browning, J., Shih, H., Hengerer, T., Sheikh, K., Dreykluft, K., Finsterbusch, T., Schenkenberger, I., Frommhold, R., Hren, A., Shaoulian, E., Fleets, J., Shanes, J., Seese, M., Shalaby, A., Witt, P., Shah, G., Mather, N., Seide, H., Holt, A., Ullig, T., Seals, A., Mercer, S., Schulman, D., Schneider, W., Schneider, R., Fekete, A., Schaefer, S., Clifton, R., Savin, V., Lafave, J., Sandberg, J., Schomburg, J., Samal, A., Ball, E., Sacco, J., Nelson, T., Ruoff, G., Freeman, R., Ross, S., Schellong, S., Martin, C., Rosen, R., Barnhorst, M., Rosado, J., Szymanowski, N., Schaefer, A., Kuehlenborg, A., Rinke, A., Pilipenko, H., Rack, K., Kuhlmann, M., Proskynitopoulos, N., Pohl, W., Lewinsky, D., Piechatzek, R., Raddatz, K., Mueller-Glamann, M., Barbera, S., Hollihan, P., Roehll, W., Cherrico, M., Muegge, A., Robinson, J., Braun, D., Riofrio, K., Pazier, P., Richwine, R., Stanley, E., Vogt, S., Mitrovic, V., Renzi, M., Wroblewski, J., Redondo, V., Domingo, D., Rama, P., Hemmen, C., Quinn, J., Reed, C., Quinlan, E., Rafla, E., Quadrel, M., Ebert, J., Pugeda, J., Sham, L., Pudi, K., Frahm, E., Meyer-Pannwitt, U., Braemer, U., Lowe, K., Pribble, A., Neeper, L., Pratt, R., Cush, S., Poulathas, A., Kirk, D., Pezzella, S., Brown, F., Pettis, K., Morlando, F., Petruzziello, F., Chacon, L., Peters, P., Duncan, D., Pentz, W., Montayne, S., Pearlstein, R., Gorry, N., Pavon, H., Dennison, K., Patnam, S., Joseph, L., Oza, S., Gonzalez, M., Osborne, J., Garcia, L., Orchard, R., McCormick, J., Meissner, G., Hoefer, K., Maus, O., Wulf, M., Luttermann, M., Venneklaas, U., Lueders, S., Grosse, B., Lohrbaecher-Kozak, I., Bauch, F., Koenig, H., Meusel, P., Kleinecke-Pohl, U., Schoen, B., Oppenheimer, K., Thakkar, N., Jungmair, W., Schmid, S., Junggeburth, J., Fink, P., Oberoi, M., Horacek, T., Schuppe, M., Hoffmann, S., Dorn, S., Hoffmann, U., Dieckheuer, U., Heuer, H., Peitz, M., Hartmann, A., Otto, A., Grigat, C., Manuela, W., Fuchs, R., Schneider, K., Forck-Boedeker, K., Faghih, M., Herfurth, B., Drescher, T., Kranz, P., Degtyareva, E., Ayasse, D., Daut, W., Kara, M., Contzen, C., Weihrauch, D., Buhr, M., Ladenburger, K., Braun, R., Schnelzer, P., Wilmot, M., Bouzo, M., Sehr, B., Beyer-Westendorf, J., Vierbeck, S., Berrouschot, J., Dichristin, U., Bernhardt, P., Wurow, A., Al-Zoebi, A., Duprat, C., Roudaut, R., Leparree, S., Poulard, J., Corbut, S., Kacet, S., Deruche, E., Hermida, J., Arfaoui, M., Dinanian, S., El Jarroudi, M., Decoulx, E., Berger, N., Coisne, D., Dias, P., Blanc, J., Berbari, H., Belhassane, A., Boyer, M., Babuty, D., Boursin, P., Amarenco, P., Nielsen, R., El Jarroudi, F., Nomanee, S., Agraou, B., Nguyen, T., Goza, J., Le Heuzey, J., Nappila, H., Virtanen, V., Salminen, O., Rasi, H., Sankari, T., Nyman, K., Viitaniemi, J., Maenpaa, A., Laheaar, M., Lucijanic, T., Lappalainen, T., Jakala, P., Valpas, S., Hussi, E., Kaarleenkaski, S., Huikuri, H., Ratnik, E., Vahula, V., Rajasalu, R., Rosenthal, A., Voitk, J., Paumets, M., Rivis, L., Laane, E., Kolk, R., Stern, A., Kaik, J., Nallasivan, M., West, M., Naidu, J., Parker, A., Nadar, V., Oehmann, V., Murphy, A., Raziano, S., Mullen, P., Todd, S., Mowdy, M., Schuler, C., Mounsey, P., Parrott, N., Mouhaffel, A., Serup-Hansen, K., Wiggers, H., Bowman, B., Morledge, J., Garner, S., Jakobsen, U., Torp-Pedersen, C., Svenningsen, A., Sand, N., Raae, D., Raymond, I., Petrovic, V., Overgaard, K., Olsen, R., Nielsen, H., Veng-Olsen, T., Iversen, H., Madsen, H., Ibsen, H., Loof, A., Hassager, C., Christensen, L., Christensen, H., Dodt, K., Zidkova, E., Moran, J., Samkova, D., Strugatsky, S., Mody, F., Gryczan, J., Miller, S., Vodnansky, P., Sanchez, S., Miller, R., Sanders, D., Labrova, R., Spinar, J., Spacek, R., Milas, J., Romero-Colon, J., Michlin, B., Slaby, J., Reichert, P., Jirsova, E., Podrazil, P., Pisova, J., Havlova, I., Petrova, I., Peterka, K., Olsr, J., Nechanicky, R., Melichar, M., Krocova, E., Machova, V., Ludka, O., Cajulis, C., Kvasnicka, J., Kuchar, R., Kovar, P., Kosek, Z., Kostkova, G., Kochrt, M., Kobza, R., Jirmar, R., Jerabek, O., Jelinek, Z., Jarkovsky, P., Jandik, J., Hubac, J., Honkova, M., Gregor, P., Golan, L., Francek, L., Florian, J., Ferkl, R., Elbl, L., Cermak, O., Burianova, H., Brtko, M., Kunkelova, V., Berka, L., Brodova, P., Bar, M., Bergovec, M., Vrazic, H., Bakliza, Z., Sutalo, K., Kirner, D., Steiner, R., Cvitkusic Lukenda, K., Samardzic, P., Buksa, B., Knezevic, A., Jaksic Jurinjak, S., Jelic, V., Makar Ausperger, K., Francetic, I., Romic, I., Ferri Certic, J., Tusek, S., Ciglenecki, N., Jeric, M., Car, S., Carevic, V., Bagatin, J., Perdomo Mejia, I., Sanchez Vallejo, G., Gonzales, C., Quintero, A., Fonseca, J., Orozco Linares, L., Lopez Giraldo, D., Moncada Corredor, M., Rivera Rodriguez, E., Manzur, F., Builes, A., Jaramillo Munoz, C., Delgado, P., Hernandez, H., Aldana Diaz, I., Fernandez Ruiz, R., Arroyave, C., Delgado Restrepo, J., Leon Pineda, L., Cano, N., Accini, M., Accini, J., Zhang, Y. L., Zhou, S. X., Li, B. G., Zheng, Z. Q., Wang, J. Q., Zhao, X. L., Han, R. J., Zhao, R. P., Kang, H., Zhang, Z., Lin, Y. N., Zhang, H. Q., Qiang, H., Yuan, Z. Y., Li, L. L., Yu, B., Xu, Y. P., Yin, Y. H., Gao, M., Zheng, Y., Zheng, X., Yang, Y. J., Li, A. Y., Yang, K., Liang, Y. Z., Xu, Y. M., Gu, J. Y., Xu, J. H., Li, Y. E., Wu, S. L., Huang, D., Wei, M., Shi, X. J., Wang, G. P., Qi, S. Y., Wang, D. M., Yang, Z. Y., Ma, S. M., Lu, Z. H., Liu, L., Gu, X. J., Liao, D. N., Liu, Y., Li, Z. Q., Liu, B., Li, W. M., Kong, Y. Q., Li, T. F., Liu, H., Li, L., Qu, Z., Jiang, X. J., Qiu, Y., Hong, L., You, Z. G., Hong, K., Zhang, P., Fu, G. S., Feng, C., Dong, Y. G., Zhang, X., Chen, X. P., Xie, X. D., Chen, J. Z., Xu, G. L., Bai, F., Grandon Azua, M., Yovaniniz, P., Lara Lara, C., Stockins, B., Campisto, Y., Zapata Staub, J., Potthoff, S., Torres Carrasco, G., Pincetti, C., Carmona Perez, M., Opazo, M., Romero Llamas, R., Martinez, D., Manriquez Silva, L., Manriquez, L., Rebolledo, C., Lopetegui, M., Arratia Diaz, P., Florenzano, F., Parada, A., Corbalan, R., Obreque, C., Cobos, J., Mondaca Mondaca, P., Bugueno, C., Retamal Matus, L., Balboa, W., Mabee, J., Woodford, T., Caterini, T., Wharton, S., Morley, A., Wahby, R., Giesbrecht, L., Velthuysen, G., Teitelbaum, J., Teitelbaum, I., Tremblay, M., Talbot, P., David, D., Talajic, M., Bobbie, C., Syan, G., Kailey, P., Sussman, J., St-Hilaire, R., Silverio, G., Shu, D., Marchand, C., Rupka, D., Bozek, B., Ricci, J., Nethercott, C., Qureshi, A., Mercado, A., Cervellione, K., Mendelson, R., Turri, L., Polasek, P., Sardin, V., Pesant, Y., Carroll, L., Parkash, R., Bolton, R., O'Mahony, W., Banville, P., O'Hara, G., Nicholson, R., Lamoureux, U., Najarali, A., Krider, J., Mucha, M., Roth, M., Morrison, D., Morely, A., Mawji, A., Studenikow, E., Maranda, C., Vaillancourt, T., Malette, P., Matthews, J., MacCallum, C., Seib, M., Ma, P., Douglas, S., Luton, R., Roberts, P., Lichtenstein, T., Lam, H., Lam, S., St-Germain, L., Lainesse, A., Dewar, C., Labonte, R., Roy, M., Kouz, S., Perkins, L., Huynh, T., Standring, R., Hoag, G., Ho, V., Ho, K., Scott, L., Heath, J., Hatheway, R., Houbraken, D., Viau, C., Fortin, C., Zondag, M., Eikelboom, J., Dufresne, M., Kubanska, A., du Preez, M., Denis, I., Coutu, B., Masson, C., Costi, P., Gauthier, M., Constance, C., Valley, S., Cleveland, D., Vansickle, L., Chilvers, M., Lepage, C., Chehayeb, R., Otis, J., Cha, J., Hundseth, M., Bose, S., Stafford, C., Bhargava, R., Antle, S., Archibald, J., Manoylov, E., Kitova, M., Tzekova, M., Tumbeva, D., Tumbev, H., Nyagina, M., Todorov, G., Momchilova-Lozeva, D., Staneva, A., Vasilev, I., Popov, A., Milusheva, T., Petranov, S., Kostov, K., Pencheva, G., Vasilev, D., Nikolov, F., Stoyanovski, V., Mincheva, V., Miteva, B., Mihov, A., Manolova, A., Kamenova, P., Hergeldjieva, V., Kinova, E., Goudev, A., Kostova, E., Georgiev, B., Wall, J., Gergova, V., Donova, T., Milcheva, N., Denchev, S., Parishev, G., Chompalova, B., Zimmermann, E. Burger, Zimmermann, S., Almeida, M., Boas, F. Villas, Lustosa, E., Sobral Filho, D., Carraro, A., Simoes, M., Vicente, C., Saraiva, J., do Val, R., Sampaio, R., Pagnan, L. Goncalves, dos Santos, F. Rossi, Rodrigues, D., Rodrigues, A., Rocha, M. Rubia, Rodrigues, L., Barros, R., Rocha, J., Leipelt, J., Katz Weiand, L. Reis, Avellar, K., Reis, G., Gozalo, A., Almeida, J. Pimenta, Luiz, R. Osorio, Leaes, P., Morales, K., Sebba Barroso de Souza, W. Kunz, Radaelli, G., Kalil, C., Almeida, A., Kaiser, S., Cury, C., Jorge, J., Pereira, L., Jaeger, C., Ninho, L., Guimaraes, A., Gomes, A., Gomes, M., Pereira, G., Gagliardi, R., Daitz, C., Finimundi, H., Araujo, E., Ferreira, L., Seroqui, M., Saporito, W. Faustino, Morgado, S., Dutra, O., Laimer, R., Duda, N., Pereira, V., De Patta, M., Barroso, D., Costantini, C., Silva, J., Chaves Junior, H., Fleck, N., Brondani, R., Cunha, S., Botelho, R., Sehnem, E., Precoma, D. Bertolim, Ferraz, R. Franchin, Alves da Costa, F. Augusto, Motta, C., Atie, J., de Melo, R. Ferreira, Lotufo, P. Andrade, Coutinho, E., Vincenzo de Paola, A. Amato, Denie, D., Wollaert, B., Beerts, C., Vrolix, M., Mestdagh, I., Vervoort, G., van Welden, J., Vanwelden, J., Derycker, K., Vandekerckhove, Y., Jacobs, C., Mehrle, A., Skinner, J., Meholick, A., Marti, J., Mega, J., Lack, A., Stockman, D., Huyberechts, D., Scavee, C., Clinckemaille, N., Parque, J., Raepers, M., Mairesse, G., Malmendier, D., Herzet, J., Meeusen, K., Heidbuchel, H., Tincani, G., Desfontaines, P., De Bruyne, L., De Tollenaere, M., de Koning, K., De Bleecker, J., Banaeian, F., Capiau, L., O'Shea, V., Szto, G., Perrett, L., Purnell, P., Batta, C., Paul, V., Li, J., McKeirnan, M., Morrison, H., Wright, J., Wright, A., Chung, A., Watkin, R., Gilchrist, M., Venkataraman, A., Lehman, R., Jones, S., Gates, P., Flecknoe-Brown, S., Silver, G., Davis, S., Kay, S., Dart, A., Slattery, A., Crimmins, D., Price-Smith, S., Colquhoun, D., Hoffmann, B., Arstall, M., Paraskevaidis, T., Anderson, C., Morell, Y., Vico, M., Teves, M., Sosa Liprandi, M., Morara, P., Severino, P., Buzzetti, C., Schygiel, P., Walker, M., Turner, W., Bridge, C., Storey, R., Goloboulicz, A., Schmidberg, J., Kennard, S., Sopher, M., McLaurin, B., Young, G., Kwong, Winghan J., Antman, Elliott M., Ruff, Christian T., Wang, J. H., Iriarte, M., Morissette, A., Wang, Kaijun, Li, Haiyan, and Yalcin, R.
- Subjects
Male ,medicine.medical_specialty ,Complications ,Time Factors ,Pyridines ,Health Status ,Embolism ,Hemorrhage ,Arrhythmias ,030204 cardiovascular system & hematology ,03 medical and health sciences ,0302 clinical medicine ,Quality of life ,Risk Factors ,Surveys and Questionnaires ,Internal medicine ,Atrial Fibrillation ,Humans ,Medicine ,In patient ,Prospective Studies ,030212 general & internal medicine ,anticoagulation ,Blood Coagulation ,Original Research ,Aged ,Aged, 80 and over ,Quality and Outcomes ,business.industry ,Anticoagulants ,Atrial fibrillation ,Middle Aged ,bleeding ,medicine.disease ,Stroke ,Thiazoles ,Treatment Outcome ,quality of life ,utility ,Physical therapy ,Cardiology ,Female ,Warfarin ,Gastrointestinal Hemorrhage ,Cardiology and Cardiovascular Medicine ,business ,TIMI ,Health Services and Outcomes Research ,Factor Xa Inhibitors - Abstract
Background The impact of different types of extracranial bleeding events on health‐related quality of life and health‐state utility among patients with atrial fibrillation is not well understood. Methods and Results The ENGAGE AF ‐ TIMI 48 (Effective Anticoagulation With Factor Xa Next Generation in Atrial Fibrillation–Thrombolysis in Myocardial Infarction 48) Trial compared edoxaban with warfarin with respect to the prevention of stroke or systemic embolism in atrial fibrillation. Data from the EuroQol‐5D ( EQ ‐5D‐3L) questionnaire, prospectively collected at 3‐month intervals for up to 48 months, were used to estimate the impact of different categories of bleeding events on health‐state utility over 12 months following the event. Longitudinal mixed‐effect models revealed that major gastrointestinal bleeds and major nongastrointestinal bleeds were associated with significant immediate decreases in utility scores (−0.029 [−0.044 to −0.014; P P =0.001], respectively). These effects decreased in magnitude over time, and were no longer significant for major nongastrointestinal bleeds at 9 months, but remained borderline significant for major gastrointestinal bleeds at 12 months. Clinically relevant nonmajor and minor bleeds were associated with smaller but measurable immediate impacts on utility (−0.010 [−0.016 to −0.005] and −0.016 [−0.024 to −0.008]; P Conclusions All categories of bleeding events were associated with negative impacts on health‐state utility in patients with atrial fibrillation. Major bleeds were associated with relatively large immediate decreases in utility scores that gradually diminished over 12 months; clinically relevant nonmajor and minor bleeds were associated with smaller immediate decreases in utility that persisted over 12 months. Clinical Trial Registration URL: https://www.clinicaltrials.gov/ . Unique identifier: NCT00781391.
- Published
- 2017
30. Association of cystatin C with major adverse cardiac events in patients with type 2 diabetes mellitus after acute coronary syndrome
- Author
-
Ovrakh, T., primary and Serik, S., additional
- Published
- 2018
- Full Text
- View/download PDF
31. Paraprosthetic Complications After Endoprosthesis Replacement of Pelvis Joint with Implants
- Author
-
Baimagambetov, Shalginbay A., primary, Balgazarov, Serik S., additional, Ramazanov, Zhanatay K., additional, Belan, Yelena A., additional, Abilov, Ruslan S., additional, Dolgov, Alexey A., additional, and Balgazarov, Amangol S., additional
- Published
- 2018
- Full Text
- View/download PDF
32. Outcomes With Edoxaban Versus Warfarin in Patients With Previous Cerebrovascular Events Findings From ENGAGE AF-TIMI 48 (Effective Anticoagulation With Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in Myocardial Infarction 48)
- Author
-
Pan, Y. F., Lim, G., Desire, A., Tseng, W. K., Rost, Natalia S., Grammer, M., Khetarpal, S., Waseem, M., Zellner, C., Roper, E., Amin, M., Harden, M., Sababathi, R., Valpas, S., Bourlios, P., Kawaguchi, A., Mavronasiou, E., Pandurangi, U., Shams, S., Dichristin, U., Purayil, M. Padinhare, Munemasa, M., Angel, J., Gurusamy, P., Berni, A., Platner, N., Zeltser, D., El Jarroudi, M., Kisos, D., Haruna, T., Bernhardt, P., Coisne, D., Nakahara, Y., Li, W. M., Karamitsos, C., Tziortziotis, A., Essop, M., Nunkoo, T., Gani, M., Wilson, L., Kelfkens, Y., Mitha, I., Taljaard, J., Naidoo, D., Duki, Y., Snyders, F., Munnik, M., Soma, P., Johnston, H., Patki, N., Jasani, B., Van Der Merwe, N., Goosen, Y., Van Zyl, L., Le Roux, M., Venter, T., Wessels, L., Bae, H. J., Han, M. G., Cha, J. K., Kim, D. H., Cho, B. R., Ryu, D. R., Choi, H. H., Hong, K. S., Chung, W. S., Oh, Y. S., Han, S. H., Lee, K. H., Hong, T. J., Lee, H. W., Hyon, M. S., Jung, J. W., Jeon, H. K., Lee, J. M., Kang, D. H., Choi, K. J., Kim, C. J., Jin, E. S., Kim, D. S., Seo, J. S., Kim, H. S., Cha, M. J., Kim, J. T., Park, M. S., Kim, J. H., Park, J. H., Kim, J. S., Parekh, P., Vicente, C., Simoes, M., Carraro, A., Sobral Filho, D., Lustosa, E., Boas, F. Villas, Almeida, M., Zimmermann, S., Zimmermann, E. Burger, Kunkelova, V., Berka, L., Brodova, P., Bar, M., Bergovec, M., Vrazic, H., Matsushita, C., Premchand, R., Boyer, M., Bakliza, Z., Sutalo, K., Kirner, D., Steiner, R., Cvitkusic Lukenda, K., Samardzic, P., Buksa, B., Kartsagkoulis, E., Kaplan, P., Sopher, M., Young, G., Senior, R., Roberts, J., Mackin, A., Moriarty, A., Olympios, C., Green, M., Shandra, T., Zhurba, S., Logvinov, Y., Zharinov, O., Mudruk, I., Yena, L., Nahrebetskyy, V., Kraiz, I., Chompalova, B., Parishev, G., Kharalkar, H., Knezevic, A., Denchev, S., Usan, N., Kraydashenko, O., Milcheva, N., Stets, R., Donova, T., Gergova, V., Georgiev, B., Kostova, E., Goudev, A., Jaksic Jurinjak, S., Kinova, E., Hergeldjieva, V., Yagensky, A., Kamenova, P., Manolova, A., Vasilev, I., Mihov, A., Miteva, B., Kupnovytska, I., Mincheva, V., Jelic, V., Stoyanovski, V., Makar Ausperger, K., Nikolov, F., Vasilev, D., Pencheva, G., Kostov, K., Petranov, S., Boriani, G., Milusheva, T., Popov, A., Staneva, A., Momchilova-Lozeva, D., Francetic, I., Todorov, G., Nyagina, M., Tumbev, H., Tumbeva, D., Tzekova, M., Kitova, M., Manoylov, E., Dicker, D., Giovannelli, F., Archibald, J., Antle, S., Bhargava, R., Stafford, C., Bose, S., Hundseth, M., Cha, J., Otis, J., Romic, I., Ferri Certic, J., Chehayeb, R., Lepage, C., Tusek, S., Ciglenecki, N., Jeric, M., Chilvers, M., Car, S., Carevic, V., Vansickle, L., Kyyak, Y., Serik, S., Cleveland, D., Valley, S., Constance, C., Gauthier, M., Lasri, E., Costi, P., Masson, C., Coutu, B., Denis, I., du Preez, M., Kubanska, A., Dufresne, M., Krider, J., Eikelboom, J., Zondag, M., Fortin, C., Viau, C., Houbraken, D., Hatheway, R., Mabee, J., Bagatin, J., Lizogub, V., Atar, S., Heath, J., Scott, L., Ho, K., Perdomo Mejia, I., Ho, V., Hoag, G., Standring, R., Huynh, T., Perkins, L., Kouz, S., Roy, M., Labonte, R., Fuki, Y., Dewar, C., Lainesse, A., St-Germain, L., Lam, S., Lam, H., Lichtenstein, T., Roberts, P., Luton, R., Douglas, S., Sanchez Vallejo, G., Ma, P., Seib, M., MacCallum, C., Matthews, J., Malette, P., Vaillancourt, T., Maranda, C., Studenikow, E., Mawji, A., Morely, A., Morrison, D., Roth, M., Mucha, M., Volkov, V., Goncharov, O., Vizir, V., Sklyanna, O., Vatutin, M., Drapchak, I., Vakaliuk, I., Dharmarao, A., Zanwar, I., Thakur, B., Vinod, M. Vijan, Kaur, A., Marciano, C., Varma, S., Tykhonova, S., Kuznetsov, I., Tseluyko, V., Najarali, A., Lamoureux, U., Nicholson, R., O'Hara, G., Banville, P., O'Mahony, W., Bolton, R., Parkash, R., Carroll, L., Pesant, Y., Sardin, V., Polasek, P., Turri, L., Qureshi, A., Nethercott, C., Ricci, J., Gonzales, C., Gorna, O., Bozek, B., Rupka, D., Malynovsky, Y., Quintero, A., Belhassane, A., Fonseca, J., Orozco Linares, L., Marchand, C., Shu, D., Silverio, G., St-Hilaire, R., Fedotov, S., Morissette, A., Sussman, J., Ostrovska, L., Kailey, P., Syan, G., Lopez Giraldo, D., Moncada Corredor, M., Bobbie, C., Rivera Rodriguez, E., Talajic, M., David, D., Manzur, F., Talbot, P., Tremblay, M., Teitelbaum, I., Teitelbaum, J., Velthuysen, G., Giesbrecht, L., Wahby, R., Morley, A., Wharton, S., Caterini, T., Builes, A., Dimitra, K., Ajioka, M., Woodford, T., Balboa, W., Ushakova-Sokolova, L., Parkhomenko, A., Dovgan, N., Potapenko, P., Nekrasa, A., Prokhorov, O., Leonidova, V., Rebrov, B., Gamachek, O., Jaramillo Munoz, C., Daskalaki, A., Thankaraj, L., Moschos, N., Delgado, P., Hernandez, H., Aldana Diaz, I., Fernandez Ruiz, R., Arroyave, C., Delgado Restrepo, J., Leon Pineda, L., Srinivas, A., Cano, N., Accini, M., Accini, J., Zhang, Y. L., Zhou, S. X., Li, B. G., Zheng, Z. Q., Wang, J. Q., Zhao, X. L., Rishko, M., Chendey, T., Han, R. J., Zhao, R. P., Retamal Matus, L., Bugueno, C., Mondaca Mondaca, P., Cobos, J., Obreque, C., Corbalan, R., Parada, A., Kang, H., Gupta, R., Singh, G., Lyzohub, S., Florenzano, F., Arratia Diaz, P., Lopetegui, M., Rebolledo, C., Manriquez, L., Manriquez Silva, L., Martinez, D., Romero Llamas, R., Opazo, M., Carmona Perez, M., Pincetti, C., Torres Carrasco, G., Zhang, Z., Lin, Y. N., Rudyk, I., Zhang, H. Q., Qiang, H., Yuan, Z. Y., Li, L. L., Yu, B., Potthoff, S., Zapata Staub, J., Rodriguez, M., Campisto, Y., Xu, Y. P., Stockins, B., Lara Lara, C., Yovaniniz, P., Grandon Azua, M., Bai, F., Xu, G. L., Chen, J. Z., Xie, X. D., Chen, X. P., Zhang, X., Yin, Y. H., Gao, M., Dong, Y. G., Feng, C., Fu, G. S., Zhang, P., Miyauchi, Y., Hong, K., You, Z. G., Shatilo, V., Ishchuk, V., Zheng, Y., Hong, L., Zheng, X., Qiu, Y., Yang, Y. J., Shcherbak, V., Sudheer, R., Shetty, G., Li, A. Y., Goncharova, I., Yang, K., Liang, Y. Z., Xu, Y. M., Gu, J. Y., Xu, J. H., Li, Y. E., Wu, S. L., Huang, D., Wei, M., Shvetz, N., Shi, X. J., Wang, G. P., Qi, S. Y., Wang, D. M., Yang, Z. Y., Ma, S. M., Lu, Z. H., Liu, L., Gu, X. J., Sychov, O., Liao, D. N., Liu, Y., Zamlynskyy, M., Sirenko, Y., Stanislavchuk, M., Sethia, S., Sethia, A., Jiang, X. J., Li, Z. Q., Qu, Z., Li, L., Perebetiuk, L., Liu, H., Kandekar, B., Li, T. F., Liu, B., Raut, N., Kong, Y. Q., Hashimoto, Y., Jakala, P., Shimazu, Y., Hiasa, Y., Berger, N., Kale, V., Alexopoulos, D., Wurow, A., Filardi, P. Perrone, Al-Zoebi, A., Hoffmann, S., Viitaniemi, J., Dias, P., Oomaan, A., Murata, J., Natarajan, S., Narendra, J., Shelke, S., Duprat, C., Winter, K., Roudaut, R., Wolde, C., Buelow-Johansen, B., Oga, Y., Namjoshi, D., Lee, M. H., Leparree, S., Poulard, J., Nagai, Y., Sakata, Y., Naito, S., Oyama, H., Nishi, Y., Nagase, T., Ochiai, J., Junko, H., Ogawa, T., Sugeno, M., Oguro, H., Tanabe, M., Okada, K., Corbut, S., Moriyama, Y., Okajima, K., Nakashima, M., Okazaki, O., Wada, H., Kacet, S., Okishige, K., Kitani, S., Okumura, K., Deruche, E., Hermida, J., Dorn, S., Tsalihin, D., Hoffmann, U., Dieckheuer, U., Heuer, H., Winkelmann, B., Peitz, M., Hartmann, A., Otto, A., Grigat, C., Antman, Elliott M., Mercuri, Michele F., Ito, Y., Onishi, M., Iwade, K., SomaRaju, Bhupathi, Nicolau, Jose C., Singhal, Aneesh B., Silverman, Scott, Norden, Andrew D., Crompton, Andrea E., Murphy, Sabina A., Ruff, Christian T., Giugliano, Robert P., Narita, Y., Onaka, H., Moriyama, H., Ozaki, Y., Tanikawa, I., Sakagami, S., Nakano, A., Sakuragi, S., Hayashi, N., Sakurai, S., Ooki, H., Sasaki, T., Braunwald, Eugene, Oosawa, N., Satoh, A., Fujimoto, E., Seino, Y., Narumi, M., Shirai, T., Shigenari, M., Shoji, Y., Ueda, J., Manuela, W., Fuchs, R., Schneider, K., Sakuma, Y., Forck-Boedeker, K., Arfaoui, M., Dinanian, S., Joshi, H., Faghih, M., Weyland, K., Park, S. J., Kim, S. H., Buchholz, M., Seo, J. B., Kim, Y. J., Aggarwal, R., Smith, S., Beeton, I., Dunn, S., Blagden, M., Ito, T., Vogelmann, O., Gonzalez, C., Ahuad Guerrero, R., Belatsky, V., Swissa, M., Aloni, I., Sugi, K., Miyazaki, E., Price, R., Sumii, K., Camm, J., Asakura, H., Dougal, K., Chapman, O., Davies, D., Choy, A., Duff, J., Cohen, A., Wilmott, R., D'Costa, D., Douglas, H., Dickinson, D., Lie, F., Ramasamy, V., Lindsay, S., Takagi, M., Mohri, S., Takahashi, W., Yoshida, K., Voehringer, Voehringer, Thomas, R., Herfurth, B., Ludwig, I., Drescher, T., Kranz, P., Degtyareva, E., Ayasse, D., Veltkamp, R., Agraou, B., Zarpentin, C., Taggeselle, J., Stoehring, R., Shochat, M., Sterlin, J., Iwasaki, T., Schiff, E., Takahashi, A., Albisu, J., Rosales, E., Atkinson, C., Allall, O., Kishi, N., Linker, N., Finlayson, M., Bonin, K., Lip, G., Spitzer, S., Masaki, W., Akihisa, U., Hirahara, T., Furiozzi, F., Zaca, V., Takahashi, T., Sakurai, Y., Baylacher, M., Reguero, M., Sohn, H., Takeda, K., Gold, G., Yahata, A., Takenaka, T., Yamagishi, K., El Jarroudi, F., Sethi, K., Seibert, H., Takeuchi, S., Gagliano, M., Toschi, V., Breschi, M., Severi, S., Hussi, E., Watanabe, E., Cannoni, S., Rasura, M., Singh, R., Brown, R., Sawhney, J., Arora, T., Iesaka, Y., Higashikata, T., Miyamoto, C., Nagatome, H., Iijima, T., Higuchi, K., Kaarleenkaski, S., Ino, H., Hellmers, J., Noguchi, H., Schreckenberg, A., Schmidt, M., Schmidt, A., Schiewe, C., Dreykluft, K., Daut, W., Kakinoki, S., Finsterbusch, T., Adachi, C., Schenkenberger, I., Frommhold, R., Lioy, E., Penco, M., Schellong, S., Inomata, T., Nakamura, K., Kamakura, S., Granzow, K., Nakahara, F., Kamijo, M., Iida, S., Tanaka, K., Raisaro, A., Uchida, M., Tanouchi, J., Kamiyama, K., Nishiya, Y., Tsuboi, H., Tsuboi, N., Fujii, R., Terakura, K., Kato, K., Ishida, A., Kazatani, Y., Uematsu, M., Yasumoto, S., Ueyama, Y., MacCallum, P., Usuda, K., Sakai, Y., Yagi, M., Sato, A., Yagi, H., Kuroda, T., Yamabe, H., Ichikawa, Y., Sakamoto, Y., Yamada, T., Yamano, R., Kitazawa, H., Alvarez, C., Yamagishi, T., Sasaki, S., Yamamoto, Y., Yamashina, A., Chun, M. Y., Joung, B. Y., Igarashi, C., Ebano, P., Takiguchi, M., Yamashita, T., Matsuda, K., Yonehara, T., Yoshino, H., Nomura, H., MacLeod, M., Yoshioka, K., Fujiwara, Y., Bayram Llamas, E., Hurtado, A., Calvo Vargas, C., Cedano Limon, M., Kobayashi, Y., Cardona Munoz, E., Hernandez, S., Carrillo, J., Szymanowski, N., Schaefer, A., Kuehlenborg, A., Rinke, A., Delgadillo, T., Casares Ramirez, M., Franco Valles, J., Pilipenko, H., Rack, K., Garcia, M., Ameriso, S., Ameriso, P., Garcia, N., Alcantara Colin, M., Garcia-Castillo, A., McGhee, C., Jaramillo, A., Leiva-Pons, J., de la Mora, S., Marazzi, P., Llamas Esperon, G., Grajales, A., Amuchastegui, M., Jones, D., Mendez-Machado, G., Avila, H., Nevarez Ruiz, L., Magallanes, G., Sanchez Diaz, C., Ortiz, A., Kuhlmann, M., Maxwell, T., Velasco Sanchez, R., Logvinenko, S., Moran Velazquez, E., Isted, C., Alhakim, M., More, R., Helliwell, L., van Welsen, I., Bruning, T., Caceres, M., Jones, A., Buiks, C., de Groot, J., Radder, I., de Vos, R., Beloscar, J., Hazeleger, R., Daniels, R., Kietselaer, B., Muijs, L., Mannaerts, H., Kooiman, E., Mevissen, H., van der Heijden, D., Hofmeyer, H., Anscombe, R., O'Meeghan, T., Kjentjes, M., Benatar, J., White, H., Borthwick, L., Doughty, R., Copley, M., Fisher, R., Monkley, R., Green, B., Scott, D., Hamer, A., Tomlinson, J., Hart, H., Turner, A., Cammell, R., Troughton, R., Skelton, L., Young, C., Kennett, K., Atar, D., Claussen, H., Hofsoy, K., Melbue, R., Sandvik, J., Thunhaug, H., Tveit, A., Enger, S., Bustamante, G., Tejada Guillen, M., Cabrera, J., Esteves Mendoza, R., Chavez, C., Luna, C., Lema, J., Rozenman, Y., Givoni, H., Carrion, A., Proskynitopoulos, N., Pohl, W., Llerena, N., Lewinsky, D., Araoz Bedregal, S., Medina Palomino, F., Rodriguez, J., Minchola, J., Bautista, C., Negron Miguel, S., Honores Armas, B., Rodriguez, A., Romero, N., Torres, P., Murdoch, D., Fernandez Rodriguez, K., Yanac Chavez, P., Horna, M., Delgado, S., Babilonia, N., Sambaz, C. M., Piechatzek, R., Raddatz, K., Barcinas, R., Mueller-Glamann, M., Francis, V., Menon, J., Sharma, P., Mathur, A., Zapanta, M., Fenu, L., Coching, R., Vallenas, M., Matiga, G., Enad, C., Rogelio, G., Joaquin, F., Roxas, A., Gilo, L., Ouzan, E., Amarenco, P., To, R., Aquino, M., Villamor, L., Nario, K., Adamus, J., Korzeniowska-Adamus, J., Baszak, J., Bronisz, M., Karny, M., Bhaskarwar, P., Hara, S., Boursin, P., Babuty, D., Naganuma, M., Lee, S. H., Shin, D. G., Piseddu, G., Namgung, J., Andrews, A., Sarna, M., Cieslak, B., Newby, D., Busz-Papiez, B., Krzystolik, A., Cymerman, K., Dabrowska, M., Ptak, A., Derlaga, B., Laskowska-Derlaga, E., Domanska, E., Guziewicz, M., Gieroba, A., Zajac, E., Gniot, J., Mroczkowski, P., Januszewicz, A., Makowiecka-Ciesla, M., Huikuri, H., Jazwinska-Tarnawska, E., Flint, L., Paradiso, G., Ratnik, E., Ciezak, P., Jurowiecki, J., Kaczmarek, B., Pacholska, A., Kaminski, L., Kania, G., Tymendorf, K., Karczmarczyk, A., Kaliszczak, R., Konieczny, M., Benicka, E., Korzeniak, R., Borowski, W., Pye, M., Krzyzanowski, W., Muzyk-Osikowicz, M., Sklodowskiej-Curie, M., Jadhav, D., Hagiwara, N., Wright, L., Kus, W., Lesnik, J., Kamitake, C., Wierzykowski, T., Lewczuk, J., Furukawa, Y., Stopyra-Poczatek, M., Lubinski, A., Szymanska, K., Lysek, R., Jaguszewska, G., Matyszczak-Toniak, L., Sznajder, R., Wnetrzak-Michalska, R., Kosmaczewska, A., Mazur, S., Chmielowski, A., Miekus, P., Kosmalska, K., Mosiewicz, J., Myslinski, W., Napora, P., Petrucci, J., Berli, M., Biniek, D., Nessler, J., Nessler, B., Niezgoda, K., Nej, A., Nowak, J., Olszewski, M., Podjacka, D., Budassi, N., Janczewska, D., Itamoto, K., Pogorzelska, H., Ise, M., Valle, M., Bustamante Labarta, G., Polaszewska-Pulkownik, V., Bojanowska, E., Raczak, G., Zienciuk-Krajka, A., Rewinska, H., Rozmyslowicz-Szerminska, W., Yamaguchi, A., Ronkowski, R., Ruzyllo, W., Norwa-Otto, B., Sendrowski, D., Spyra, J., Szolkiewicz, M., Vahula, V., Malanska, A., Turbak, R., Wrobel, W., Muzalewski, P., Wysokinski, A., Avery, D., Kennard, S., Storey, R., Bridge, C., Turner, W., Walker, M., Rajasalu, R., Venkataraman, A., Gilchrist, M., Kudlicki, J., Zarebinski, M., Rosenthal, A., Krauze, R., Zielinski, M., Nawrot, M., Matias, F., Correia, J., Gil, V., Lopes, S., Madeira, J., Maymone, D., Sant, H., Martins, D., Neves, E., Monteiro, P., Oliveira, D., Leitao Marques, A., Salgado, A., Goncalves, A., Santos, O., Veiga Pais Nunes, L., Santos, J., Barbera, S., Soares, D., Albulescu, P., Joseph, J., Bulgari, M., Funazaki, T., Metra, M., Ciortea, M., Apetrei, E., Lishner, M., Matei, C., Bartos, D., Badila, E., Bengus, C., Ochean, V., Bobescu, E., Doka, B., Bolohan, F., Ciobotaru, G., Andor, M., Coman, I., Ghionea, M., Constantinescu, M., Creteanu, M., Oommen, D., Watkin, R., Chung, A., Wright, A., Wright, J., Parasteac, M., Cristea, M., Joseph, S., Anciu, M., Crisu, D., Pahuja, M., Jemna, D., Jain, R., Ghume, A., Hiremath, J., Thakor, G., Saravia, M., Caccavo, A., Muegge, A., Hardas, S., Dobre, I., Voicu, O., Dobreanu, D., Sirbu, I., Dragomir, D., Savanth, P., Jurca, S., Iosipescu, L., Costache, L., Minescu, B., Serban, D., Pop, C., Cozma, M., Popescu, M., Ardelean, A., Sipciu, D., Plosca, P., Stamate, S., Spinu, C., Topolnitchi, L., Tudoran, M., Tudoran, C., Zhukova, N., Arutyunov, G., Chernyavskaya, T., Ballyuzek, M., Alexandrova, L., Barbarash, O., Bashkireva, A., Voitk, J., Fujimoto, C., Bart, B., Larina, V., Belenky, D., Kosolapov, Y., Berns, S., Yukhno, E., Bokarev, I., Khlevchuk, T., Chumakova, G., Pokutneva, O., Demko, A., Masin, A., Dovgalevsky, P., Puchinyan, N., Drapkina, O., Fracaro, V., Cartasegna, L., Zyatenkova, E., Egorova, L., Esip, V., Kirichek, N., Filatov, A., Soin, I., Gilinskaya, O., Valuyshkih, E., Glezer, M., Valovyeva, S., Golitsyn, S., Kratskina, T., Goloshchekin, B., Laptev, I., Gratsiansky, N., Mazovets, O., Karpov, Y., Buza, V., Kosenko, B., Vogt, S., Khirmanov, V., Kireenkov, I., Khokhlov, A., Sinitsina, O., Khokhlov, R., Novas, V., Tsareva, E., Khrustalev, O., Khrustalev, A., Kostenko, V., Karabalieva, S., Koziolova, N., Polyanskaya, E., Kozyrev, O., Kostenko, O., Kuznetsov, V., Paumets, M., Rychkov, A., Lavrova, O., Tereschenko, L., Levashov, S., Volkova, E., Libis, R., Maslova, A., Libov, I., Kwak, J. J., Moiseeva, Y., Lila, A., Belousova, L., Lukyanov, Y., Lamden, D., Nikolaev, K., Nikolaev, A., Nikolskaya, I., Khromova, O., Novikova, N., Patrusheva, S., Panchenko, E., Laguta, P., Panov, A., Nilk, R., Polkanova, E., Matveeva, I., Poluyanova, N., Pikalova, N., Raskina, T., Letaeva, M., Rebrov, A., Karoli, N., Repin, M., Rodina, N., Shaposhnik, I., Lebedev, E., Shogenov, Z., Agirov, M., Sidorenko, B., Vorontsova, S., Sinitsina, I., Orlov, V., Sizova, Z., Rha, S. W., Caruso, O., Saa Zarandon, R., Lapidus, N., Sobolev, K., Na, J. O., Colombo, H., Morandini, M., Cuello, J., Erofeeva, S., Suprun, E., Dronov, D., Fukuda, N., Harada, J., Tarasov, N., Isakov, L., Tereshenko, S., Fukamizu, S., Kositsyna, I., Tikhonova, E., Solovyev, A., Timofeev, A., Bulygin, S., Ustyugov, S., Rossovskaya, M., Vishnevsky, A., Kirgizova, A., Volkov, D., Yakusevich, V., Petrochenko, A., Yakushin, S., Nikulina, N., Zateyshchikov, D., Zotova, I., Zateyshchikova, A., Mankhaeva, B., Zenin, S., Kononenko, O., Rim, S. J., Kim, J. Y., Zubeeva, G., Motylev, I., Apostolovic, S., Arcocha Torres, M., Djordjevic-Radojkovic, D., Manzanal Rey, A., Blanco Coronado, J., Puertas, I., Bruguera Cortada, J., Maenpaa, A., Cabero, P., Calvo, C., Rosell, M., Calvo, G., De Arce Borda, A., Asensio, A., Diez Tejedor, E., Perez Guevara, M., Celic, V., Gonzalez Juanatey, J., Laheaar, M., Moure, M., Lucijanic, T., Mitrovic, V., Frahm, E., Mardikar, H., Hernandez Madrid, A., Lappalainen, T., Delgado, A., Lopez Garcia-Aranda, V., Barquero, R., Meyer-Pannwitt, U., Kale, M., Lavhe, P., Anthony, A., Majstorovic, A., Kumbla, M., Adjic, N. Cemerlic, Bjelobrk, M., Despotovic, N., Erceg, P., Ilic, S., Ilic, B., Krotin, M., Djokovic, A., Miloradovic, V., Djokic, I., Otasevic, P., Tasic, N., Potpara, T., Polovina, M., Putnikovic, B., Kalezic, T., Cuneo, C., Seferovic, P., Milinkovic, I., Tavciovski, D., Davicevic, Z., Vasiljevic-Pokrajcic, Z., Mitrovic, P., Tesic, B. Vujisic, Ostojic, M., Castro, C., Manzano, L., Blanco Abril, S., Rivis, L., Merino, J., Topolnitchi, O., Diaz-Pintado, M., Bocanera, M., D'Amico, A., Cendali, G., Dran, R., Moreno, V., Arias, J., Ruda, M., Golshmid, M., Fernandez, M., Fernandez Alvarez, R., Terns, M., Tesic, M., Ambrovicova, V., Ambrovic, I., Banikova, A., Dukat, A., Dachs Delgado, M., Kosmalova, V., Dulkova, K., Dulka, T., Francis, J., Kumar, A., Duris, T., Estol, C., Davolos, M., Vankova, L., Villuendas, R., Astier, L., Appelros, P., Dzupina, A., Dzupinova, M., Hatalova, K., Hatala, R., Akerberg, A., Karpuram, M., Facello, A., Hranai, M., Hofmanova, J., Blom, K. Berndtsson, Facello, M., Falu, E., Kasperova, V., Kumar, P., Lawande, A., Reptova, A., Mazur, J., Pella, D., Fedacko, J., Mason, T., Zeig, S., Curtis, S., Zakhary, B., Fisher, M., Yousuf, K., Dongas, B., Yi, J., Preston, S., Yasin, M., Kulkarni, G., Sheehan, T., Andersson, R., Blomstrom, P., Persson, L., Carlsson, T., Bengtsson, A. Stener, Hadan, S., Iriarte, M., Femenia, F., Arrieta, M., Fuselli, J., Deokar, M., Kulkarni, R., Zanotti, A., Dettmann, S., Ostberg, S., Engdahl, J., Karlsson, L., Herlitz, J., Winberg, L., Juul-Moller, S., Jernhed, H., Koskinen, P., Hakansson, E., Kozak, P., Edlund, M., Malmqvist, L., Eriksson, G., Singh, P., Randers, F., Moodh, J., Gupta, J., Saini, A., Rautio, A., Johansson, M., Goyal, N., Ronn, F., Sundholm, C., Stenberg, A., Gunnarsson, A., Thulin, J., Broberg, M., Yarows, S., Moccetti, T., Slater, I. Petrova, Cheng, C. C., Wu, W. S., Mostert, M., Engelbrecht, J., Botha, L., Pointer, S., Worley, S., Capasso-Gulve, E., Wood, K., VonGerichten, S., Willis, J., Mali, N., Chopda, M., Babbolin, M., Merlini, P., Francalacci, G., Fujita, T., Karnwal, N., Somaraju, B., Marino, P., Raggi, F., Calambur, N., Dowling, C., Williams, R., Gibson, C., Williams, D., Truva, C., Westcott, J., St Laurent, B., Weiss, R., Sanchez, G., Waxman, F., Locklear, T., Ward, S., Renaud, K., Walsh, R., Kilcup, S., Vossler, M., Washam, M., Vijay, N., Warren, K., Vicari, R., Parsons, T., Verma, S., Cardoza, T., Vemireddy, D., Harrelson, K. Gonzalez, Val-Mejias, J., Hanna, K., Updegrove, J., Salas, L., Ruffini, L., Morsky, J., Ellis, G., Bhuti, M., Biniwale, A., Slanina, M., Kmec, J., Tucker, P., Torres, M., Southam, D., Teixeira, J., Mitchell, T., Tee, H., Young, K., Teague, S., Dastoli, K., Tawney, K., Swauger, M., Tatarko, M., Corchado, D., Zachar, A., Kokles, M., Zareczky, P., Gant Lopez, J., Tami, L., Leo, L., Talano, J., Bruton, T., Takata, T., Springer, K., Tahirkheli, N., Herwehe, S., Szulawski, I., Rathi, A., Bhargava, V., Solanki, R., Kotiwale, V., Freemyer, D., Swerchowsky, V., Bharani, A., Frost, J., Suresh, D., Surushe, S., Vittitow, T., Struble, R., Benjarge, P., Kikuchi, R., Braemer, U., Cox, C., Steljes, A., Liu, M., Staniloae, C., McCartney, P., Spivack, E., Vasquez, E., Sperling, M., Thomason, L., Spangenthal, S., Hodnett, P., Smith, R., Keene, R., Hughes, B., Skierka, R., Nelson, M., Singh, V., Turner, K., Singh, N., Meiller, F., Garcia Duran, R., Laane, E., Chiang, C. E., Perlo, D., Garrido, M., Ceirano, C., Giacomi, G., Meyer, R., Simpson, P., Champagne, M., Siler, T., Kohno, M., Yu, W. C., Stephenson, L., Shoukfeh, M., Sheth, T., Tamura, S., Banker, D., Reddy, J., Browning, J., Babu, R., Rao, B., Nyman, K., Sankari, T., Shih, H., Rasi, H., Babu, P., Meissner, G., Shaikh, A., Lo Pinto, G., Hengerer, T., Sheikh, K., Hren, A., Shaoulian, E., Fleets, J., Eden, M., Shanes, J., Koretsune, Y., Seese, M., Avvaru, G., Shalaby, A., Witt, P., Shah, G., Mather, N., Seide, H., Holt, A., Ullig, T., Seals, A., Mercer, S., Schulman, D., Schneider, W., Schneider, R., Fekete, A., Schaefer, S., Clifton, R., Savin, V., Lafave, J., Sandberg, J., Schomburg, J., Samal, A., Ball, E., Sacco, J., Nelson, T., Giannaula, R., Ruoff, G., Freeman, R., Ross, S., Martin, C., Allman, J., Dalby, A., Rosen, R., Barnhorst, M., Chiang, F. T., Rosado, J., Wu, Y. W., Chiou, C. W., Hollihan, P., Yeh, T. C., Roehll, W., Cherrico, M., Robinson, J., Braun, D., Riofrio, K., Pazier, P., Richwine, R., Stanley, E., Renzi, M., Wroblewski, J., Redondo, V., Domingo, D., Rama, P., Hoefer, K., Hemmen, C., Quinn, J., Reed, C., Quinlan, E., Rafla, E., Quadrel, M., Ebert, J., Maus, O., Pugeda, J., Sham, L., Pudi, K., Nakagawa, Y., Lowe, K., Ben Ari, M., Huerta, M., Pribble, A., Neeper, L., Pratt, R., Cush, S., Poulathas, A., Kirk, D., Pezzella, S., Gaggioli, G., Brown, F., Pettis, K., Morlando, F., Petruzziello, F., Chacon, L., Lewis, B., Peters, P., Goicoechea, R., von Wulffen, M., Hominal, M., Bianchini, M., Jure, H., Jure, D., Kevorkian, R., Duncan, D., Pentz, W., Montayne, S., Pearlstein, R., Gorry, N., Pavon, H., Dennison, K., Patnam, S., Joseph, L., Oza, S., Gonzalez, M., Osborne, J., Garcia, L., Orchard, R., McCormick, J., Oppenheimer, K., Genin, I., Laffi, Laffi, Klainman, E., Monaco, F., Lanternier, G., Belcuore, M., Liniado, G., Iglesias, M., Litvak, B., Nigro, A., Llanos, J., Vignau, S., Lorente, C., Shatsky, K., Lotti, J., Raimondi, G., Mackinnon, I., Carne, M., Manuale, O., Thakkar, N., Hsia, C. H., Chen, Y. P., Huang, J. L., Chen, Y. F., Kuo, C. T., Wang, C. L., Lai, W. T., Lin, T. H., Oberoi, M., Wilmot, M., Nielsen, R., Nomanee, S., Nguyen, T., Goza, J., Lee, J. T., Nallasivan, M., Pai, P. Y., Lin, K. H., West, M., Naidu, J., Ichishita, Y., Yumoto, I., Parker, A., Nadar, V., Oehmann, V., Murphy, A., Raziano, S., Mullen, P., Todd, S., Mowdy, M., Fujimoto, K., Schuler, C., Mounsey, P., Calderon, M., Marino, J., Parrott, N., Mouhaffel, A., Bowman, B., Majdoub, A., Hayek, T., Roshrosh, M., Morledge, J., Garner, S., Moran, J., Strugatsky, S., Mody, F., Gryczan, J., Miller, S., Sanchez, S., Miller, R., Sanders, D., Milas, J., Romero-Colon, J., Michlin, B., Cajulis, C., Mercado, A., Cervellione, K., Mendelson, R., Wall, J., Mehrle, A., Skinner, J., Meholick, A., Marti, J., Mega, J., Lack, A., McLaurin, B., Omae, K., Paul, J., McKnight, T., Rodkey, K., McKenzie, M., Miranda, J., McGuire, K., Schwarz, L., McGarvey, J., Stubbs, L., McCartney, M., Hicks, T., Massin, E., Bedenko, E., Marenberg, M., Hasin, Y., Rabadi-Marar, D., Kurabayashi, M., Marar, I., Mandviwala, M., Dagan, T., Casas, R., Makam, S., Shyu, K. G., Funes, I., Lisiecki, B., Mainigi, S., Fujimoto, S., Muntaner, J., Doctor, A., Magee, A., Bush, D., Macomber, J., Edelstein, J., Lurie, M., Wright, H., Lui, H., Ault, S., Looby, R., Kotera, M., Davids, M., Lone, B., Shah, D., Gandur, H., Nul, D., Lomnitz, D., Wofford, E., Littlefield, R., Murphy, R., Ling, L., Chiu, C. Z., Miller, D., Lillestol, M., Bonds, C., Lewis, D., Hartley, L., Lesser, M., Smith, D., Ueng, K. C., Bollova, D., Lentz, M., Royse, H., Ledbetter, L., Faucett, S., Langevin, E., Verdini, E., Piskorz, D., Tommasi, A., Povedano, G., Casares, E., Pozzer, D., Simmons, T., Lee, S. C., Fujii, E., Kozeni, S., Lang, J., Wang, J. H., Ferguson, D., Landau, C., Coyle, G. Stagi, Lambert, C., Jauregui, V., Laliotis, A., Marquez, D., Krichmar, P., Grossman, E., Watts, S., Kozlowski, J., Sanchez, E., Kotha, P., Godfrey, C., Rouwaida, S., Virtanen, V., Gottlieb, S., Koya, E., Fernandez, E., Prado, A., Korpas, D., Averett, P., Kindman, L., Tsai, W. C., Khan, G., Khan, M., Yeh, H. I., Binns, M., Khan, B., DiCorcia, L., Kesselbrenner, M., Buhler, A., Kersh, R., Bartholomaus, D., Kerkering, M., Keller, J., Keller, R., Davis, C., Kastelic, R., Behm, K., Karunaratne, H., Masuyama, T., Goldhaber, M., Ruggiero, M., Kapoor, A., Cook, S., Kaplan, K., Kostedt, G., Kandath, D., Dugal, J., Fujii, K., Fujiwara, M., Kai, W., Coombs, V., Kahn, B., Royes, A., Nappila, H., Judson, P., Nichols, M., Jovin, I., Hughett, G., Le Heuzey, J., Jones, R., Phillips, T., Johnson, F., Goldhaber, A., Murena, E., Grassia, V., Ghantous, R., Francis, A., Bosco, B., Andresen, T., Jardula, M., Butcher, S., Ison, R., Tambawala, M., Hussain, M., Garza, M., Hurst, P., Battistelli, E., Hunter, J., Huang, P., Craft, D., Howard, L., Hays, D., Howard, V., Adams, K., Houchin, V., Venturini, C., Shree, R., Turner, N., Hotchkiss, D., Sloss, D., Horton, K., Homayouni, A., Homan, J., Hoekstra, J., Dutter, S., Kuo, J. Y., Hippert, R., Vieira, P., Hinchman, D., Ron, G. Avraham, Elias, M., Kaneno, Y., Badenhorst, J., Carey, G., Herson, S., Ebina, E., Meno, H., Arora, V., Endo, H., Memon, A., Fattore, L., Miranda, D., Herrod, J., Batchell, K., Hermany, P., Harkins, V., Henry, S., Millard, D., Henderson, D., Jirasirirojanakorn, K., Pornchaiyasit, K., Kaewsuwanna, P., Sinthusopa, W., Kiatchoosakun, S., Dandekar, U., Heiman, M., Krater, C., Sriprasert, S., Laothavorn, P., Hearne, S., Bobade, M., Bamrungpong, P., Harris, J., Cavanna, L., Han, M., Bentivenga, L., Hamroff, G., Morelli, L., Piyayotai, D., Hack, T., McLean, R., Gvora, T., Sripracha, A., Felsman, D., Guthrie, R., Foster, B., Guerrero, Guerrero, Sritara, P., Arneja, J., Ranka, R., Guarnieri, T., Gabela, W., Guarino, J., Mabe, K., Grove, D., Davis, A., Grossman, C., Goodman, V., Griffin, J., Aull, L., Panpunuan, P., Griffin, S., Bonora, M., Graham, S., Rafala, E., Gowda, S., Goldstein, M., Latteri, J., Goldscher, D., Ewing, B., Gogia, H., Keane-Richmond, P., Gillespie, E., Hinchion, N., Gerber, J., Valentine, H., George, F., Garb, J., Jones, J., Gaffney, M., Ramos, H., Sukonthasarn, A., Mekara, W., Vorasettakarnkij, Y., Agarwal, D., Abdullakutty, J., Puripun, E., Malhan, S., Kincses, M., Vertes, A., Acikel, M., Marosi, A., Tomcsanyi, J., Satake, M., Mita, T., Di Niro, M., Szakal, I., Di Pasquale, G., Akilli, H., Demir, H., Smith, K., Friedlander, I., Morales, C., French, W., Gentry, P., Franco, M., Thrope, C., Frais, M., Solis, A., Forman, S., Slayton, C., Flores, E., Donahue, S., Fishbein, G., Drew, B., Fischell, T., Finkelstein, S., Shriver, D., Ata, N., Bayata, S., Cakmak, N., Finkel, M., Calik, A., Erasmus, L., Basson, M., Calvo, M., Fialkow, J., Prior, J., Felten, W., Mazzone, C., Tang, N., Feldman, J., Tameron, A., Feld, L., Watkins, D., Cayli, M., Fahmy, R., DeSalle, D., Ceyhan, C., Everhart, B., Shipp, A., Ettinger, N., O'Brien, J., Johnson, C., Erenrich, N., Cristaldi, J., Ellis, J., Quick, R., Eldadah, Z., Dunn, K., Eade, J., Cullen, T., D'Souza, A., Habibi, S., Drozdiak, R., Olson, A., Dotani, I., Rodriguez, L., Donovan, D., Tisdale, L., DiGiovanna, M., Ucik, S., Dhar, S., Briscoe, C., Devenport, S., Waters, L., Steward, A., Desai, A., Poynton, M., Carey, J., DeGarmo, R., Warmack, D., Dean, J., Debes, C., De Lemos, J., Ebreo, N., Davuluri, A., Dave, B., Dave, K., Wulf, A., Datta, S., Leka, G., Daniels, S., Morgan, T., Dang, N., Sarpola, N., Curtis, B., Nelson, L., Cowan, L., Masson, E., Cottiero, R., Mullinax, K., Cossu, S., Svadbik, L., Corbett, B., Martinez, E., Concha, M., Cole, J., Salpas, S., Colan, D., Bossaers, J., Cohen, R., Dutka, C., Sipos, T., McClelland, M., Clay, A., Clapp, T., Bagby, J., Ciaramita, J., Sawaya, K., Chaturvedi, S., Tamayo, M., Charlat, M., Hatfield, G., Chang, M., Phan, D., Carr, K., Jameson, L., Caplan, J., Hartranft, E., Canosa, R., Canaday, D., Morton, S., Cader, C., Al-Maliky, T., Bybee, K., Navarrete, S., Ruzsa, D., Triano, A., Brown, H., Frey, W., Brilakis, E., Terry, P., Bradley, A., Ziegler, K., Bowden, W., Simor, T., Wade, W., Bognar, A., Bouchard, A., Hickenbotham, D., Borsheim, M., Vernon, M., Blue, B., Bloomberg, K., Bloomberg, R., Ensminger, E., Blonder, R., Talbot-Lawson, C., Block, T., Antonino, M., Bingham, S., Langone, L., Bilazarian, S., Bilal, B., Eldred, R., Bernard, J., Ibarra, M., Sayour, A., Toth, S. Rostasne, Palinkas, A., Berk, M., Nagy, A., Garman, V., Bensimhon, D., Swaim, D., Beinart, S., Craig, M., Bedwell, N., Luis-Valdes, M., Bedoya, R., Hoffman, T., Beasley, R., Kolumban, E., Merkely, B., Kiss, K., Wulf, M., Takeda, M., Benton, J., Bartkowiak, A., Gordon, L., Erdogan, D., Barrington, P., Faircloth, C., Barker, T., Altonen, D., Barber, M., Campbell, G., Baman, R., Batista, M., Baine, S., Thompson, B., Ayesu, K., Ermis, C., Alvarez, M., Sanchez, A., Bowen, L., Sanjurjo, M., Codutti, O., Saravia Toledo, S., Formoso, I., Schmidberg, J., Baldwin, E., Awasty, V., Cobos, D., Aude, Y., Strickland, S., Medvegy, M., Kiss, T., Attanti, S., Matoltsy, A., Rasmussen, L., Arouni, A., Shoaf, R., Arnold, T., York, T., Kabul, K., Kanadasi, M., Goloboulicz, A., Anderson, J., Schygiel, P., Buzzetti, C., Severino, P., Morara, P., Sosa Liprandi, M., Teves, M., Vico, M., Oto, A., Turgut, O., Persechino, F., Morell, Y., Amin, K., Lane, B., Alsheikh, T., MacDonald, H., Almquist, A., Anderson, C., Paraskevaidis, T., Kolk, R., Tandogan, I., Stern, A., Yigit, F., Yigit, Z., Arstall, M., Hoffmann, B., Colquhoun, D., Price-Smith, S., Crimmins, D., Slattery, A., Karakai, H. Horvathne, Lupkovics, G., Di Lenarda, A., Kovacs, Z., Gadepalli, R., Mariani, M., Kumagai, S., Luttermann, M., Krishnan, H., Dart, A., Venneklaas, U., Kay, S., Lueders, S., De Servi, S., Grosse, B., Davis, S., Baranyai, M., Silver, G., Flecknoe-Brown, S., Gates, P., Kovacs, I., Salminen, O., Koczka, M., Jakal, A., Jones, S., Pirelli, S., Lohrbaecher-Kozak, I., Bauch, F., Koenig, H., Lehman, R., Kiss, R., Saha, D., Barai, A., Roy, D., Bekal, S., Feil, J. Felfoldine, Meusel, P., Morrison, H., Biscardi, R., Kis, E., Hirayama, A., Allison, J., Godsey, W., Aliyar, P., Genova-Peeva, E., Kosztyu, M., Kleinecke-Pohl, U., Alexander, J., Brubaker, S., Akhter, F., Schoen, B., Reddy, R., Shankar, A. Ravi, Jungmair, W., Schmid, S., Junggeburth, J., De Pace, D., Ahmadpour, H., De Caterina, R., Hussain, A., Kaik, J., Ahmad, A., Beck, P., Zoghi, M., Batushkin, V., Fink, P., Reiling, S., Miyamoto, N., Adler, P., McKeirnan, M., Li, J., Paul, V., Batta, C., Serup-Hansen, K., Vuriya, A., Horacek, T., Schuppe, M., Kanakaridisz, N., Varga, A., Kimizu, T., Purnell, P., Perrett, L., Kishore, R., Szto, G., O'Shea, V., Capiau, L., Banaeian, F., De Bleecker, J., de Koning, K., De Tollenaere, M., Kara, M., Fiok, J., Szatmari, J., De Bruyne, L., Edes, I., Tsukimine, A., Muskoczki, E., Wiggers, H., Jakobsen, U., Torp-Pedersen, C., Forgione, C., Harada, K., Dioszeghy, P., Almaraz, S. Padilla, Desfontaines, P., Tincani, G., Heidbuchel, H., Camas, L. Velasquez, Cuccia, C., Meeusen, K., Herzet, J., Malmendier, D., Guerra, L., Mairesse, G., Raepers, M., Parque, J., Clinckemaille, N., Scavee, C., Samayoa, C. Sanchez, Pozuelos, J. Mayen, Arakawa, S., Huyberechts, D., Stockman, D., Jacobs, C., Vandekerckhove, Y., Svenningsen, A., Sand, N., Azhdari, M., Derycker, K., Peruzzotti, L., Comi, G., Vanwelden, J., Mino, K., Cervi, E., Sanchez, M., Gilat, T., van Welden, J., Vervoort, G., Mestdagh, I., Vrolix, M., Bazylevych, A., Vlasyuk, Z., Raae, D., Raymond, I., Beerts, C., Wollaert, B., Denie, D., Vincenzo de Paola, A. Amato, Coutinho, E., Lotufo, P. Andrade, de Melo, R. Ferreira, Atie, J., Motta, C., Alves da Costa, F. Augusto, Lahav, M., Estrada, M. Rodas, Ferraz, R. Franchin, Precoma, D. Bertolim, Guevara, S., Contzen, C., Weihrauch, D., Sehnem, E., Botelho, R., Cunha, S., Brondani, R., Fleck, N., Buhr, M., Kandekar, S., Ladenburger, K., Lavagnino, A. Ovando, Braun, R., Ishimaru, S., Chaves Junior, H., Silva, J., Costantini, C., Barroso, D., Jimenez, T., De Patta, M., Pereira, V., Duda, N., Bereznyakov, I., Laimer, R., Tomita, H., Ishii, Y., Dutra, O., Morgado, S., Saporito, W. Faustino, Seroqui, M., Ferreira, L., Araujo, E., Finimundi, H., Daitz, C., Gagliardi, R., Pereira, G., Gomes, M., Gomes, A., Guimaraes, A., Lebedynskaya, M., Petrovic, V., Overgaard, K., Ninho, L., Olsen, R., Nielsen, H., Jaeger, C., Barash, B., Veng-Olsen, T., Dotsenko, S., Pereira, L., Iversen, H., Madsen, H., Kulynych, R., Dzyak, G., Vasilyeva, L., Faynyk, A., Sorokivskyy, M., Gavrysyuk, V., Schnelzer, P., Ibsen, H., Adler, J., Dzublik, Y., Horbach, L., Husyev, V., Bouzo, M., Babbar, A., Loof, A., Blanc, J., Godlevska, O., Melgar, I. Guzman, Marcoviciu, D., Ramirez, V. de Leon, Sehr, B., Beyer-Westendorf, J., Vierbeck, S., Decoulx, E., Samburg, Y., Jorge, J., Cury, C., Karpenko, O., Hassager, C., Milla, O. Ayau, Kaiser, S., Christensen, L., Christensen, H., Dodt, K., Zidkova, E., Samkova, D., Vodnansky, P., Almeida, A., Kalil, C., Radaelli, G., Sebba Barroso de Souza, W. Kunz, Morales, K., Labrova, R., Nevolina, I., Karpenko, Y., Leaes, P., Luiz, R. Osorio, Blihar, O., Kaydashev, I., Berbari, H., Spinar, J., Spacek, R., Almeida, J. Pimenta, Gozalo, A., Slaby, J., Reichert, P., Jirsova, E., Podrazil, P., Gerasimenko, N., Pisova, J., Exarchou, E., Havlova, I., Petrova, I., Kifnidis, K., Reis, G., Kolomyyits, S., Peterka, K., Olsr, J., Bansal, N., Nechanicky, R., Vasylets, V., Kopytsya, M., Melichar, M., Krocova, E., Machova, V., Ludka, O., Petyunina, O., Kotseruba, V., Berrouschot, J., Kvasnicka, J., Avellar, K., Kuchar, R., Kovar, P., Katz Weiand, L. Reis, Korantanis, K., Kosek, Z., Kostkova, G., Leipelt, J., Rocha, J., Ishibashi, Y., Lohman, J., Panella, M., Nozaki, T., Abi-Mansour, P., Dvoieglazova, M., Pyrgakis, V., Koval, V., Ohirko, O., Kochrt, M., Kobza, R., Koval', O., Jirmar, R., Sakamoto, S., Jerabek, O., Jelinek, Z., Jarkovsky, P., Jandik, J., Hubac, J., Honkova, M., Barros, R., Gregor, P., Rao, M., Jambula, H., Golan, L., Anzai, T., Rodrigues, L., Rocha, M. Rubia, Rodrigues, A., Rodrigues, D., dos Santos, F. Rossi, Pagnan, L. Goncalves, Sampaio, R., do Val, R., Saraiva, J., Francek, L., Florian, J., Ferkl, R., Elbl, L., Cermak, O., Burianova, H., Brtko, M., Pinto, B., and Yalcin, R.
- Subjects
Male ,medicine.medical_specialty ,Pyridines ,medicine.medical_treatment ,030204 cardiovascular system & hematology ,Brain Ischemia ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Double-Blind Method ,Recurrence ,Edoxaban ,Internal medicine ,Atrial Fibrillation ,parasitic diseases ,Secondary Prevention ,medicine ,Humans ,Myocardial infarction ,cardiovascular diseases ,Stroke ,Aged ,Advanced and Specialized Nursing ,business.industry ,Hazard ratio ,Warfarin ,Anticoagulants ,Atrial fibrillation ,Thrombolysis ,Middle Aged ,medicine.disease ,nervous system diseases ,Thiazoles ,Treatment Outcome ,chemistry ,Anesthesia ,Cardiology ,Female ,Neurology (clinical) ,Cardiology and Cardiovascular Medicine ,business ,030217 neurology & neurosurgery ,TIMI ,medicine.drug - Abstract
Background and Purpose— Patients with atrial fibrillation and previous ischemic stroke (IS)/transient ischemic attack (TIA) are at high risk of recurrent cerebrovascular events despite anticoagulation. In this prespecified subgroup analysis, we compared warfarin with edoxaban in patients with versus without previous IS/TIA. Methods— ENGAGE AF-TIMI 48 (Effective Anticoagulation With Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in Myocardial Infarction 48) was a double-blind trial of 21 105 patients with atrial fibrillation randomized to warfarin (international normalized ratio, 2.0–3.0; median time-in-therapeutic range, 68.4%) versus once-daily edoxaban (higher-dose edoxaban regimen [HDER], 60/30 mg; lower-dose edoxaban regimen, 30/15 mg) with 2.8-year median follow-up. Primary end points included all stroke/systemic embolic events (efficacy) and major bleeding (safety). Because only HDER is approved, we focused on the comparison of HDER versus warfarin. Results— Of 5973 (28.3%) patients with previous IS/TIA, 67% had CHADS 2 (congestive heart failure, hypertension, age, diabetes, prior stroke/transient ischemic attack) >3 and 36% were ≥75 years. Compared with 15 132 without previous IS/TIA, patients with previous IS/TIA were at higher risk of both thromboembolism and bleeding (stroke/systemic embolic events 2.83% versus 1.42% per year; P P P P =0.02). No treatment subgroup interactions were found for primary efficacy ( P =0.86) or for intracranial hemorrhage ( P =0.28). Conclusions— Patients with atrial fibrillation with previous IS/TIA are at high risk of recurrent thromboembolism and bleeding. HDER is at least as effective and is safer than warfarin, regardless of the presence or the absence of previous IS or TIA. Clinical Trial Registration— URL: http://www.clinicaltrials.gov . Unique identifier: NCT00781391.
- Published
- 2016
33. Cardioversion of Atrial Fibrillation in ENGAGE AF-TIMI 48
- Author
-
Seibert, H., Bolton, R., Florian, J., Nyman, K., Viitaniemi, J., Maenpaa, A., Laheaar, M., Lucijanic, T., Lappalainen, T., Jakala, P., Valpas, S., Hussi, E., Kaarleenkaski, S., Huikuri, H., Ratnik, E., Vahula, V., Rosenthal, A., Voitk, J., Paumets, M., Rivis, L., Laane, E., David, D., Kolk, R., Stern, A., Kaik, J., Serup-Hansen, K., Wiggers, H., Jakobsen, U., Torp-Pedersen, C., Svenningsen, A., Sand, N., Raae, D., Raymond, I., Petrovic, V., Overgaard, K., Olsen, R., Nielsen, H., Veng-Olsen, T., Iversen, H., Madsen, H., Ibsen, H., Loof, A., Hassager, C., Christensen, L., Christensen, H., Dodt, K., Zidkova, E., Samkova, D., Vodnansky, P., Labrova, R., Spinar, J., Spacek, R., Slaby, J., Reichert, P., Jirsova, E., Podrazil, P., Pisova, J., Havlova, I., Petrova, I., Peterka, K., Olsr, J., Nechanicky, R., Melichar, M., Krocova, E., Machova, V., Ludka, O., Kvasnicka, J., Kuchar, R., Kovar, P., Kosek, Z., Kostkova, G., Kochrt, M., Kobza, R., Jirmar, R., Jerabek, O., Jelinek, Z., Jarkovsky, P., Jandik, J., Hubac, J., Honkova, M., Gregor, P., Eikelboom, J., Krider, J., Dufresne, M., Kubanska, A., du Preez, M., Talbot, P., Denis, I., Coutu, B., Masson, C., Costi, P., Gauthier, M., Constance, C., Valley, S., Cleveland, D., Vansickle, L., Chilvers, M., Lepage, C., Chehayeb, R., Otis, J., Cha, J., Hundseth, M., Bose, S., Stafford, C., Bhargava, R., Antle, S., Archibald, J., Manoylov, E., Kitova, M., Tzekova, M., Tumbeva, D., Tumbev, H., Nyagina, M., Todorov, G., Momchilova-Lozeva, D., Staneva, A., Vasilev, I., Popov, A., Milusheva, T., Petranov, S., Kostov, K., Pencheva, G., Vasilev, D., Nikolov, F., Stoyanovski, V., Mincheva, V., Miteva, B., Mihov, A., Manolova, A., Kamenova, P., Hergeldjieva, V., Kinova, E., Goudev, A., Kostova, E., Georgiev, B., Gergova, V., Donova, T., Milcheva, N., Denchev, S., Parishev, G., Chompalova, B., Zimmermann, E. Burger, Zimmermann, S., Almeida, M., Boas, F. Villas, Lustosa, E., Sobral Filho, D., Carraro, A., Simoes, M., Vicente, C., Saraiva, J., do Val, R., Sampaio, R., Pagnan, L. Goncalves, dos Santos, F. Rossi, Rodrigues, D., Rodrigues, A., Rocha, M. Rubia, Rodrigues, L., Barros, R., Rocha, J., Leipelt, J., Katz Weiand, L. Reis, Avellar, K., Reis, G., Gozalo, A., Almeida, J. Pimenta, Luiz, R. Osorio, Leaes, P., Morales, K., Sebba Barroso de Souza, W. Kunz, Radaelli, G., Kalil, C., Almeida, A., Kaiser, S., Cury, C., Jorge, J., Pereira, L., Jaeger, C., Ninho, L., Guimaraes, A., Gomes, A., Hong, K., Gomes, M., Pereira, G., Gagliardi, R., Daitz, C., Finimundi, H., Araujo, E., Ferreira, L., Seroqui, M., Saporito, W. Faustino, Morgado, S., Dutra, O., Laimer, R., Campisto, Y., Duda, N., Pereira, V., De Patta, M., Barroso, D., Costantini, C., Silva, J., Berka, L., Chaves Junior, H., Fleck, N., Brondani, R., Cunha, S., Botelho, R., Sehnem, E., Precoma, D. Bertolim, Ferraz, R. Franchin, Alves da Costa, F. Augusto, Motta, C., Atie, J., de Melo, R. Ferreira, Lotufo, P. Andrade, Coutinho, E., Vincenzo de Paola, A. Amato, Denie, D., Wollaert, B., Beerts, C., Vrolix, M., Mestdagh, I., Vervoort, G., van Welden, J., Vanwelden, J., Derycker, K., Vandekerckhove, Y., Jacobs, C., Stockman, D., Huyberechts, D., Scavee, C., Clinckemaille, N., Parque, J., Raepers, M., Mairesse, G., Malmendier, D., Herzet, J., Meeusen, K., Heidbuchel, H., Tincani, G., Desfontaines, P., De Bruyne, L., De Tollenaere, M., de Koning, K., Zhang, P., De Bleecker, J., Banaeian, F., Capiau, L., O'Shea, V., Szto, G., Perrett, L., Purnell, P., Batta, C., Paul, V., Li, J., McKeirnan, M., Morrison, H., Lehman, R., Jones, S., Gates, P., Roberts, J., Flecknoe-Brown, S., Silver, G., Davis, S., Kay, S., Dart, A., Slattery, A., Crimmins, D., Price-Smith, S., Colquhoun, D., Hoffmann, B., Arstall, M., Paraskevaidis, T., Anderson, C., Morell, Y., Vico, M., Teves, M., Sosa Liprandi, M., Morara, P., Severino, P., Buzzetti, C., Schygiel, P., Goloboulicz, A., Schmidberg, J., Formoso, I., Saravia Toledo, S., Codutti, O., Sanjurjo, M., Bowen, L., Sanchez, A., Alvarez, M., Rodriguez, M., Navarrete, S., Ramos, H., Venturini, C., Prado, A., Fernandez, E., Pozzer, D., Casares, E., Povedano, G., Tommasi, A., Piskorz, D., Verdini, E., Nul, D., Muntaner, J., Funes, I., Marino, J., Calderon, M., Manuale, O., Li, Y. E., Carne, M., Mackinnon, I., Raimondi, G., Lotti, J., Shatsky, K., Lorente, C., Vignau, S., Llanos, J., Nigro, A., Litvak, B., Iglesias, M., Liniado, G., Belcuore, M., Lanternier, G., Monaco, F., Kevorkian, R., Jure, D., Jure, H., Bianchini, M., Hominal, M., von Wulffen, M., Goicoechea, R., Huerta, M., Giannaula, R., Eden, M., Giacomi, G., Ceirano, C., Garrido, M., Perlo, D., Garcia Duran, R., Meiller, F., Gant Lopez, J., Stockins, B., Zanotti, A., Fuselli, J., Arrieta, M., Femenia, F., Iriarte, M., Falu, E., Facello, M., Facello, A., Davolos, M., Estol, C., Moreno, V., Dran, R., Cendali, G., D'Amico, A., Bocanera, M., Cuneo, C., Rosell, M., Cuello, J., Morandini, M., Colombo, H., Saa Zarandon, R., Caruso, O., Novas, V., Cartasegna, L., Fu, G. S., Fracaro, V., Caccavo, A., Saravia, M., Bustamante Labarta, G., Valle, M., Budassi, N., Berli, M., Petrucci, J., Beloscar, J., Caceres, M., Amuchastegui, M., Ameriso, P., Ameriso, S., Garcia, M., Alvarez, C., Reguero, M., Allall, O., Rosales, E., Albisu, J., Bar, M., Bergovec, M., Vrazic, H., Bakliza, Z., Sutalo, K., Lara Lara, C., Kirner, D., Steiner, R., Cvitkusic Lukenda, K., Samardzic, P., Buksa, B., Knezevic, A., Jaksic Jurinjak, S., Jelic, V., Makar Ausperger, K., Francetic, I., Romic, I., Xu, J. H., Ferri Certic, J., Gu, J. Y., Tusek, S., Ahuad Guerrero, R., Gonzalez, C., Vogelmann, O., Giugliano, Robert P., Peterson, Nancy, Nordio, Francesco, De Caterina, Raffaele, Ezekowitz, Michael D., Plitt, Anna, Xu, Y. M., Gandur, H., Liang, Y. Z., Ciglenecki, N., Jeric, M., Yang, K., Car, S., Feng, C., Li, A. Y., Carevic, V., Yovaniniz, P., Bagatin, J., Perdomo Mejia, I., Sanchez Vallejo, G., Kunkelova, V., Brtko, M., Yang, Y. J., Burianova, H., Liao, D. N., Gu, X. J., Grandon Azua, M., Bai, F., Zapata Staub, J., Cermak, O., Truva, C., Hong, L., Dong, Y. G., Qiu, Y., Potthoff, S., Liu, H., Rajasalu, R., Liu, L., Lu, Z. H., Ma, S. M., Yang, Z. Y., Wang, D. M., Qi, S. Y., Wang, G. P., Qiang, H., Zhang, H. Q., Lin, Y. N., Shi, X. J., Wang, J. Q., Zhang, X., Elbl, L., Gonzales, C., Chen, X. P., Xie, X. D., Ferkl, R., Chen, J. Z., Xu, G. L., Zhao, X. L., Han, R. J., Zhao, R. P., Kang, H., Zhang, Z., Wei, M., Quintero, A., Cobos, J., Obreque, C., Corbalan, R., Fonseca, J., Francek, L., Caterini, T., Orozco Linares, L., Lopez Giraldo, D., Moncada Corredor, M., Wharton, S., Parkash, R., Nethercott, C., Ricci, J., Carroll, L., Xu, Y. P., Yu, B., Li, L. L., Rivera Rodriguez, E., Morley, A., Mondaca Mondaca, P., Bugueno, C., Manzur, F., Retamal Matus, L., Pesant, Y., Builes, A., Jaramillo Munoz, C., Balboa, W., Mabee, J., Sardin, V., Woodford, T., Polasek, P., Turri, L., Li, L., Delgado, P., Parada, A., Hernandez, H., Florenzano, F., Aldana Diaz, I., Fernandez Ruiz, R., Arratia Diaz, P., Qureshi, A., Lopetegui, M., O'Mahony, W., Rebolledo, C., Manriquez, L., Arroyave, C., Manriquez Silva, L., Martinez, D., Romero Llamas, R., Opazo, M., Bozek, B., Banville, P., Wahby, R., Rupka, D., Delgado Restrepo, J., Li, Z. Q., Liu, Y., Grammer, M., Waseem, M., Roper, E., Leon Pineda, L., Harden, M., Carmona Perez, M., Zellner, C., Mason, T., Zeig, S., Curtis, S., Zakhary, B., Fisher, M., Yousuf, K., Dongas, B., Yi, J., Preston, S., Yasin, M., Sheehan, T., Yarows, S., Pointer, S., Worley, S., Giesbrecht, L., Capasso-Gulve, E., Wood, K., VonGerichten, S., Velthuysen, G., Teitelbaum, J., Willis, J., Dowling, C., Williams, R., Gibson, C., Teitelbaum, I., Tremblay, M., Yin, Y. H., Williams, D., Westcott, J., St Laurent, B., Weiss, R., Sanchez, G., Waxman, F., Locklear, T., Ward, S., Renaud, K., Walsh, R., Kilcup, S., Vossler, M., Washam, M., Vijay, N., Warren, K., Vicari, R., Parsons, T., Verma, S., Cardoza, T., Vemireddy, D., Harrelson, K. Gonzalez, Val-Mejias, J., Hanna, K., Updegrove, J., Salas, L., Tucker, P., Romero, N., Marchand, C., Torres, M., Southam, D., Teixeira, J., Mitchell, T., Shu, D., Tee, H., Young, K., Teague, S., Silverio, G., Dastoli, K., Tawney, K., St-Hilaire, R., Pincetti, C., Qu, Z., Cano, N., Jiang, X. J., Liu, B., Li, W. M., Swauger, M., Tatarko, M., Yuan, Z. Y., Corchado, D., Tami, L., Leo, L., Torres Carrasco, G., Accini, M., Golan, L., Kong, Y. Q., Talano, J., Bruton, T., Takata, T., Springer, K., Tahirkheli, N., Herwehe, S., Szulawski, I., Freemyer, D., Swerchowsky, V., Frost, J., Suresh, D., Vittitow, T., Struble, R., Cox, C., Steljes, A., Liu, M., Staniloae, C., McCartney, P., Spivack, E., Vasquez, E., Sperling, M., Thomason, L., Spangenthal, S., Li, T. F., Hodnett, P., Smith, R., Keene, R., Smith, S., Hughes, B., Skierka, R., Nelson, M., Singh, V., Turner, K., Singh, N., Meyer, R., Accini, J., Simpson, P., Champagne, M., Siler, T., Stephenson, L., Shoukfeh, M., Browning, J., Shih, H., Hengerer, T., Sheikh, K., Hren, A., Shaoulian, E., Fleets, J., Shanes, J., Seese, M., Shalaby, A., Witt, P., Shah, G., Mather, N., Seide, H., Holt, A., Ullig, T., Seals, A., Mercer, S., Schulman, D., Schneider, W., Schneider, R., Fekete, A., Schaefer, S., Clifton, R., Zhang, Y. L., Zhou, S. X., Wu, S. L., Li, B. G., Savin, V., Lafave, J., Sandberg, J., Huang, D., Schomburg, J., Zheng, Z. Q., Samal, A., Ball, E., Sacco, J., Nelson, T., Ruoff, G., Freeman, R., Ross, S., Martin, C., Rosen, R., Barnhorst, M., Rosado, J., Hollihan, P., Roehll, W., Cherrico, M., Robinson, J., Braun, D., Riofrio, K., Pazier, P., Richwine, R., Stanley, E., Renzi, M., Wroblewski, J., Redondo, V., Domingo, D., Rama, P., Hemmen, C., Quinn, J., Reed, C., Quinlan, E., Rafla, E., Quadrel, M., Ebert, J., Pugeda, J., Sham, L., Pudi, K., Lowe, K., Pribble, A., Neeper, L., Pratt, R., Cush, S., Poulathas, A., Kirk, D., Pezzella, S., Brown, F., Pettis, K., Morlando, F., Petruzziello, F., Chacon, L., Peters, P., Duncan, D., Pentz, W., Montayne, S., Pearlstein, R., Gorry, N., Pavon, H., Dennison, K., Patnam, S., Joseph, L., Oza, S., Gonzalez, M., Osborne, J., Garcia, L., Orchard, R., McCormick, J., Oppenheimer, K., Thakkar, N., Oberoi, M., Wilmot, M., Nielsen, R., Nomanee, S., Nguyen, T., Goza, J., Nallasivan, M., West, M., Naidu, J., Parker, A., Nadar, V., Oehmann, V., Murphy, A., Raziano, S., Mullen, P., Todd, S., Mowdy, M., Schuler, C., Mounsey, P., Parrott, N., Mouhaffel, A., Bowman, B., Morledge, J., Garner, S., Moran, J., Strugatsky, S., Mody, F., Gryczan, J., Miller, S., Sanchez, S., Miller, R., Sanders, D., Milas, J., Romero-Colon, J., Michlin, B., Cajulis, C., Mercado, A., Cervellione, K., Mendelson, R., Wall, J., Mehrle, A., Skinner, J., Meholick, A., Marti, J., Mega, J., Lack, A., McLaurin, B., Paul, J., McKnight, T., Rodkey, K., McKenzie, M., Miranda, J., McGuire, K., Schwarz, L., McGarvey, J., Stubbs, L., McCartney, M., Hicks, T., Massin, E., Bedenko, E., Marenberg, M., Rabadi-Marar, D., Marar, I., Hernandez, S., Mandviwala, M., Casas, R., Makam, S., Lisiecki, B., Mainigi, S., Doctor, A., Magee, A., Bush, D., Macomber, J., Edelstein, J., Lurie, M., Wright, H., Lui, H., Ault, S., Looby, R., Davids, M., Lone, B., Shah, D., Lomnitz, D., Wofford, E., Littlefield, R., Murphy, R., Ling, L., Miller, D., Lillestol, M., Bonds, C., Lewis, D., Hartley, L., Lesser, M., Smith, D., Lentz, M., Royse, H., Ledbetter, L., Faucett, S., Langevin, E., Simmons, T., Lang, J., Ferguson, D., Landau, C., Coyle, G. Stagi, Lambert, C., Jauregui, V., Laliotis, A., Marquez, D., Krichmar, P., Watts, S., Kozlowski, J., Sanchez, E., Kotha, P., Godfrey, C., Korpas, D., Averett, P., Kindman, L., Khan, G., Khan, M., Binns, M., Khan, B., DiCorcia, L., Kesselbrenner, M., Buhler, A., Kersh, R., Bartholomaus, D., Kerkering, M., Keller, J., Keller, R., Davis, C., Kastelic, R., Behm, K., Karunaratne, H., Ruggiero, M., Kapoor, A., Cook, S., Kaplan, K., Kostedt, G., Kandath, D., Dugal, J., Kai, W., Coombs, V., Kahn, B., Royes, A., Judson, P., Nichols, M., Jovin, I., Hughett, G., Jones, R., Phillips, T., Johnson, F., Andresen, T., Jardula, M., Butcher, S., Ison, R., Tambawala, M., Hussain, M., Garza, M., Hurst, P., Battistelli, E., Hunter, J., Huang, P., Craft, D., Howard, L., Hays, D., Howard, V., Adams, K., Houchin, V., Turner, N., Hotchkiss, D., Sloss, D., Horton, K., Homayouni, A., Homan, J., Young, C., Hoekstra, J., Dutter, S., Hippert, R., Vieira, P., Hinchman, D., Carey, G., Herson, S., Miranda, D., Herrod, J., Batchell, K., Hermany, P., Harkins, V., Henry, S., Millard, D., Henderson, D., Dandekar, U., Heiman, M., Krater, C., Hearne, S., Bobade, M., Harris, J., Cavanna, L., Han, M., Bentivenga, L., Hamroff, G., Morelli, L., Hack, T., McLean, R., Gvora, T., Felsman, D., Guthrie, R., Foster, B., Guerrero, Guerrero, Guarnieri, T., Gabela, W., Guarino, J., Mabe, K., Grove, D., Davis, A., Grossman, C., Goodman, V., Griffin, J., Aull, L., Griffin, S., Bonora, M., Graham, S., Rafala, E., Gowda, S., Goldstein, M., Latteri, J., Goldscher, D., Ewing, B., Gogia, H., Keane-Richmond, P., Gillespie, E., Hinchion, N., Gerber, J., Valentine, H., George, F., Garb, J., Jones, J., Gaffney, M., Smith, K., Friedlander, I., Morales, C., French, W., Gentry, P., Franco, M., Thrope, C., Frais, M., Solis, A., Forman, S., Slayton, C., Flores, E., Donahue, S., Fishbein, G., Drew, B., Fischell, T., Lim, G., Finkelstein, S., Shriver, D., Finkel, M., Calvo, M., Fialkow, J., Prior, J., Felten, W., Tang, N., Feldman, J., Tameron, A., Feld, L., Watkins, D., Fahmy, R., DeSalle, D., Everhart, B., Shipp, A., Ettinger, N., O'Brien, J., Johnson, C., Erenrich, N., Cristaldi, J., Ellis, J., Quick, R., Eldadah, Z., Dunn, K., Eade, J., Cullen, T., D'Souza, A., Habibi, S., Drozdiak, R., Olson, A., Dotani, I., Rodriguez, L., Donovan, D., Tisdale, L., DiGiovanna, M., Ucik, S., Dhar, S., Briscoe, C., Devenport, S., Waters, L., Desire, A., Steward, A., Desai, A., Carey, J., DeGarmo, R., Warmack, D., Dean, J., Debes, C., De Lemos, J., Ebreo, N., Davuluri, A., Dave, B., Dave, K., Wulf, A., Datta, S., Leka, G., Daniels, S., Morgan, T., Dang, N., Sarpola, N., Curtis, B., Nelson, L., Cowan, L., Masson, E., Cottiero, R., Mullinax, K., Cossu, S., Svadbik, L., Corbett, B., Martinez, E., Concha, M., Cole, J., Salpas, S., Colan, D., Bossaers, J., Cohen, R., Dutka, C., Cohen, A., McClelland, M., Clay, A., Clapp, T., Bagby, J., Ciaramita, J., Sawaya, K., Chaturvedi, S., Tamayo, M., Charlat, M., Hatfield, G., Chang, M., Phan, D., Carr, K., Jameson, L., Caplan, J., Hartranft, E., Canosa, R., Dickinson, D., Canaday, D., Morton, S., Cader, C., Al-Maliky, T., Bybee, K., Triano, A., Brown, H., Frey, W., Brilakis, E., Terry, P., Bradley, A., Ziegler, K., Bowden, W., Wade, W., Bouchard, A., Hickenbotham, D., Borsheim, M., Vernon, M., Zheng, X., Blue, B., Bloomberg, K., Bloomberg, R., Ensminger, E., Blonder, R., Talbot-Lawson, C., Block, T., Antonino, M., Bingham, S., Langone, L., Bilazarian, S., Bilal, B., Eldred, R., Bernard, J., Ibarra, M., Berk, M., Brodova, P., Garman, V., Bensimhon, D., Swaim, D., Beinart, S., Craig, M., Bedwell, N., Luis-Valdes, M., Bedoya, R., Hoffman, T., Beasley, R., Benton, J., Bartkowiak, A., Gordon, L., Barrington, P., Faircloth, C., Barker, T., Altonen, D., Barber, M., Campbell, G., Baman, R., Batista, M., Baine, S., Thompson, B., Ayesu, K., Baldwin, E., Awasty, V., Cobos, D., Aude, Y., Strickland, S., Attanti, S., Rasmussen, L., Arouni, A., Shoaf, R., Arnold, T., Zheng, Y., York, T., Anderson, J., Persechino, F., Amin, M., Khetarpal, S., Amin, K., Lane, B., Alsheikh, T., MacDonald, H., Almquist, A., Biscardi, R., Allison, J., Godsey, W., Aliyar, P., Genova-Peeva, E., Alexander, J., Brubaker, S., Akhter, F., Ahmadpour, H., Hussain, A., Ahmad, A., Beck, P., Aggarwal, R., Reiling, S., Adler, P., Barash, B., Adler, J., Lohman, J., Panella, M., Abi-Mansour, P., Mackin, A., Moriarty, A., Green, M., Shandra, T., Zhurba, S., Logvinov, Y., Zharinov, O., Mudruk, I., Yena, L., Nahrebetskyy, V., Yagensky, A., Serik, S., Volkov, V., Goncharov, O., Vizir, V., Sklyanna, O., Vatutin, M., Drapchak, I., Vakaliuk, I., Tykhonova, S., Kuznetsov, I., Tseluyko, V., Lyzohub, S., Sychov, O., Perebetiuk, L., Stanislavchuk, M., Sirenko, Y., Zamlynskyy, M., Shvetz, N., Goncharova, I., Shcherbak, V., Ishchuk, V., Shatilo, V., Rudyk, I., Chendey, T., Rishko, M., Gamachek, O., Rebrov, B., Leonidova, V., Prokhorov, O., Nekrasa, A., Potapenko, P., Dovgan, N., Parkhomenko, A., Ushakova-Sokolova, L., Ostrovska, L., Fedotov, S., Malynovsky, Y., Gorna, O., Lizogub, V., Kyyak, Y., Kupnovytska, I., Stets, R., Kraydashenko, O., Usan, N., Kraiz, I., Kaplan, P., Koval', O., Ohirko, O., Koval, V., Dvoieglazova, M., Kotseruba, V., Petyunina, O., Kopytsya, M., Vasylets, V., Kolomyyits, S., Gerasimenko, N., Kaydashev, I., Blihar, O., Karpenko, Y., Nevolina, I., Karpenko, O., Samburg, Y., Godlevska, O., Husyev, V., Horbach, L., Dzublik, Y., Gavrysyuk, V., Sorokivskyy, M., Faynyk, A., Vasilyeva, L., Dzyak, G., Kulynych, R., Dotsenko, S., Lebedynskaya, M., Bereznyakov, I., Vlasyuk, Z., Bazylevych, A., Azhdari, M., Batushkin, V., Zoghi, M., Yigit, Z., Yigit, F., Tandogan, I., Turgut, O., Oto, A., Kanadasi, M., Kabul, K., Ermis, C., Erdogan, D., Ceyhan, C., Cayli, M., Calik, A., Cakmak, N., Bayata, S., Ata, N., Demir, H., Akilli, H., Acikel, M., Puripun, E., Vorasettakarnkij, Y., Mekara, W., Sukonthasarn, A., Panpunuan, P., Sritara, P., Sripracha, A., Piyayotai, D., Bamrungpong, P., Laothavorn, P., Sriprasert, S., Kiatchoosakun, S., Sinthusopa, W., Kaewsuwanna, P., Pornchaiyasit, K., Jirasirirojanakorn, K., Kuo, J. Y., Yeh, H. I., Tsai, W. C., Wang, J. H., Lee, S. C., Ueng, K. C., Pan, Y. F., Tseng, W. K., Chiu, C. Z., Shyu, K. G., Lin, K. H., Pai, P. Y., Lee, J. T., Lin, T. H., Lai, W. T., Wang, C. L., Kuo, C. T., Chen, Y. F., Huang, J. L., Chen, Y. P., Hsia, C. H., Yeh, T. C., Chiou, C. W., Wu, Y. W., Chiang, F. T., Yu, W. C., Chiang, C. E., Wu, W. S., Cheng, C. C., Slater, I. Petrova, Moccetti, T., Broberg, M., Thulin, J., Gunnarsson, A., Stenberg, A., Sundholm, C., Ronn, F., Johansson, M., Rautio, A., Moodh, J., Randers, F., Eriksson, G., Malmqvist, L., Edlund, M., Kozak, P., Hakansson, E., Koskinen, P., Jernhed, H., Juul-Moller, S., Winberg, L., Herlitz, J., Karlsson, L., Engdahl, J., Ostberg, S., Dettmann, S., Bengtsson, A. Stener, Carlsson, T., Persson, L., Blomstrom, P., Andersson, R., Blom, K. Berndtsson, Akerberg, A., Appelros, P., Astier, L., Villuendas, R., Dachs Delgado, M., Terns, M., Fernandez Alvarez, R., Fernandez, M., Arias, J., Diaz-Pintado, M., Merino, J., Blanco Abril, S., Manzano, L., Barquero, R., Lopez Garcia-Aranda, V., Delgado, A., Hernandez Madrid, A., Moure, M., Gonzalez Juanatey, J., Perez Guevara, M., Diez Tejedor, E., Asensio, A., De Arce Borda, A., Calvo, G., Calvo, C., Cabero, P., Bruguera Cortada, J., Puertas, I., Blanco Coronado, J., Manzanal Rey, A., Arcocha Torres, M., Kim, J. Y., Rim, S. J., Na, J. O., Rha, S. W., Kwak, J. J., Namgung, J., Shin, D. G., Lee, S. H., Joung, B. Y., Lee, M. H., Chun, M. Y., Kim, Y. J., Seo, J. B., Kim, S. H., Park, S. J., Kim, J. S., Park, J. H., Kim, J. H., Park, M. S., Kim, J. T., Cha, M. J., Kim, H. S., Seo, J. S., Kim, D. S., Jin, E. S., Kim, C. J., Choi, K. J., Kang, D. H., Lee, J. M., Jeon, H. K., Jung, J. W., Hyon, M. S., Lee, H. W., Hong, T. J., Lee, K. H., Han, S. H., Oh, Y. S., Chung, W. S., Hong, K. S., Choi, H. H., Ryu, D. R., Cho, B. R., Kim, D. H., Cha, J. K., Han, M. G., Bae, H. J., Wessels, L., Venter, T., Le Roux, M., Van Zyl, L., Goosen, Y., Van Der Merwe, N., Johnston, H., Soma, P., Munnik, M., Snyders, F., Duki, Y., Naidoo, D., Taljaard, J., Mitha, I., Kelfkens, Y., Wilson, L., Gani, M., Nunkoo, T., Essop, M., Mostert, M., Engelbrecht, J., Botha, L., Ellis, G., Allman, J., Dalby, A., Poynton, M., Basson, M., Erasmus, L., Badenhorst, J., Bollova, D., Zareczky, P., Kokles, M., Zachar, A., Kmec, J., Slanina, M., Morsky, J., Ruffini, L., Fedacko, J., Pella, D., Mazur, J., Reptova, A., Kasperova, V., Hofmanova, J., Hranai, M., Hatala, R., Hatalova, K., Dzupinova, M., Dzupina, A., Vankova, L., Duris, T., Dulka, T., Dulkova, K., Kosmalova, V., Dukat, A., Banikova, A., Ambrovic, I., Ambrovicova, V., Tesic, M., Golshmid, M., Ruda, M., Topolnitchi, O., Castro, C., Ostojic, M., Tesic, B. Vujisic, Mitrovic, P., Vasiljevic-Pokrajcic, Z., Davicevic, Z., Tavciovski, D., Milinkovic, I., Seferovic, P., Kalezic, T., Putnikovic, B., Polovina, M., Potpara, T., Tasic, N., Otasevic, P., Djokic, I., Miloradovic, V., Djokovic, A., Krotin, M., Ilic, B., Ilic, S., Erceg, P., Despotovic, N., Bjelobrk, M., Adjic, N. Cemerlic, Majstorovic, A., Celic, V., Djordjevic-Radojkovic, D., Apostolovic, S., Motylev, I., Zubeeva, G., Kononenko, O., Zenin, S., Mankhaeva, B., Zateyshchikova, A., Zotova, I., Zateyshchikov, D., Nikulina, N., Yakushin, S., Petrochenko, A., Yakusevich, V., Rodina, N., Volkov, D., Kirgizova, A., Vishnevsky, A., Rossovskaya, M., Ustyugov, S., Bulygin, S., Timofeev, A., Solovyev, A., Tikhonova, E., Kositsyna, I., Tereshenko, S., Isakov, L., Tarasov, N., Dronov, D., Suprun, E., Erofeeva, S., Sobolev, K., Lapidus, N., Sizova, Z., Orlov, V., Sinitsina, I., Vorontsova, S., Sidorenko, B., Agirov, M., Shogenov, Z., Lebedev, E., Shaposhnik, I., Repin, M., Karoli, N., Rebrov, A., Letaeva, M., Raskina, T., Pikalova, N., Poluyanova, N., Matveeva, I., Polkanova, E., Nilk, R., Panov, A., Laguta, P., Panchenko, E., Patrusheva, S., Novikova, N., Khromova, O., Nikolskaya, I., Nikolaev, A., Nikolaev, K., Lamden, D., Lukyanov, Y., Belousova, L., Lila, A., Moiseeva, Y., Libov, I., Maslova, A., Libis, R., Volkova, E., Levashov, S., Tereschenko, L., Lavrova, O., Rychkov, A., Kuznetsov, V., Kostenko, O., Kozyrev, O., Polyanskaya, E., Koziolova, N., Karabalieva, S., Kostenko, V., Khrustalev, A., Khrustalev, O., Tsareva, E., Khokhlov, R., Sinitsina, O., Khokhlov, A., Kireenkov, I., Khirmanov, V., Kosenko, B., Buza, V., Karpov, Y., Mazovets, O., Gratsiansky, N., Laptev, I., Goloshchekin, B., Kratskina, T., Golitsyn, S., Valovyeva, S., Glezer, M., Valuyshkih, E., Gilinskaya, O., Soin, I., Filatov, A., Kirichek, N., Esip, V., Egorova, L., Zyatenkova, E., Drapkina, O., Puchinyan, N., Dovgalevsky, P., Masin, A., Demko, A., Pokutneva, O., Chumakova, G., Khlevchuk, T., Bokarev, I., Yukhno, E., Berns, S., Kosolapov, Y., Belenky, D., Larina, V., Bart, B., Bashkireva, A., Barbarash, O., Alexandrova, L., Ballyuzek, M., Chernyavskaya, T., Arutyunov, G., Zhukova, N., Tudoran, C., Tudoran, M., Topolnitchi, L., Spinu, C., Stamate, S., Plosca, P., Sipciu, D., Ardelean, A., Popescu, M., Cozma, M., Pop, C., Serban, D., Minescu, B., Costache, L., Iosipescu, L., Jurca, S., Dragomir, D., Sirbu, I., Dobreanu, D., Voicu, O., Dobre, I., Jemna, D., Crisu, D., Anciu, M., Cristea, M., Parasteac, M., Creteanu, M., Constantinescu, M., Ghionea, M., Coman, I., Andor, M., Ciobotaru, G., Bolohan, F., Doka, B., Bobescu, E., Ochean, V., Bengus, C., Badila, E., Bartos, D., Matei, C., Apetrei, E., Ciortea, M., Albulescu, P., Soares, D., Santos, J., Veiga Pais Nunes, L., Santos, O., Goncalves, A., Salgado, A., Leitao Marques, A., Oliveira, D., Monteiro, P., Neves, E., Martins, D., Maymone, D., Madeira, J., Lopes, S., Gil, V., Correia, J., Matias, F., Nawrot, M., Zielinski, M., Krauze, R., Zarebinski, M., Kudlicki, J., Wysokinski, A., Muzalewski, P., Wrobel, W., Turbak, R., Malanska, A., Szolkiewicz, M., Spyra, J., Sendrowski, D., Norwa-Otto, B., Ruzyllo, W., Ronkowski, R., Rozmyslowicz-Szerminska, W., Rewinska, H., Zienciuk-Krajka, A., Raczak, G., Bojanowska, E., Polaszewska-Pulkownik, V., Pogorzelska, H., Janczewska, D., Podjacka, D., Olszewski, M., Nowak, J., Nej, A., Niezgoda, K., Nessler, B., Nessler, J., Biniek, D., Napora, P., Myslinski, W., Mosiewicz, J., Kosmalska, K., Miekus, P., Chmielowski, A., Mazur, S., Kosmaczewska, A., Wnetrzak-Michalska, R., Sznajder, R., Matyszczak-Toniak, L., Jaguszewska, G., Lysek, R., Szymanska, K., Lubinski, A., Stopyra-Poczatek, M., Lewczuk, J., Wierzykowski, T., Lesnik, J., Kus, W., Sklodowskiej-Curie, M., Muzyk-Osikowicz, M., Krzyzanowski, W., Borowski, W., Korzeniak, R., Benicka, E., Konieczny, M., Kaliszczak, R., Karczmarczyk, A., Tymendorf, K., Kania, G., Kaminski, L., Pacholska, A., Kaczmarek, B., Jurowiecki, J., Ciezak, P., Jazwinska-Tarnawska, E., Makowiecka-Ciesla, M., Januszewicz, A., Mroczkowski, P., Gniot, J., Zajac, E., Gieroba, A., Guziewicz, M., Domanska, E., Laskowska-Derlaga, E., Derlaga, B., Ptak, A., Dabrowska, M., Cymerman, K., Krzystolik, A., Busz-Papiez, B., Cieslak, B., Bronisz, M., Baszak, J., Korzeniowska-Adamus, J., Morissette, A., Sussman, J., Adamus, J., Nario, K., Villamor, L., Aquino, M., To, R., Gilo, L., Roxas, A., Joaquin, F., Rogelio, G., Enad, C., Matiga, G., Vallenas, M., Coching, R., Zapanta, M., Barcinas, R., Sambaz, C. M., Babilonia, N., Delgado, S., Horna, M., Yanac Chavez, P., Fernandez Rodriguez, K., Torres, P., Rodriguez, A., Honores Armas, B., Negron Miguel, S., Bautista, C., Minchola, J., Rodriguez, J., Medina Palomino, F., Araoz Bedregal, S., Llerena, N., Carrion, A., Lema, J., Luna, C., Chavez, C., Esteves Mendoza, R., Cabrera, J., Tejada Guillen, M., Bustamante, G., Enger, S., Tveit, A., Thunhaug, H., Sandvik, J., Melbue, R., Hofsoy, K., Claussen, H., Atar, D., Kennett, K., Skelton, L., Troughton, R., Cammell, R., Scott, D., Turner, A., Hart, H., Tomlinson, J., Hamer, A., Green, B., Monkley, R., Fisher, R., Copley, M., Doughty, R., Borthwick, L., White, H., Benatar, J., Kjentjes, M., O'Meeghan, T., Anscombe, R., Hofmeyer, H., van der Heijden, D., Mevissen, H., Kooiman, E., Mannaerts, H., Muijs, L., Kietselaer, B., Daniels, R., Hazeleger, R., de Vos, R., Radder, I., de Groot, J., Buiks, C., Jones, A., Bruning, T., van Welsen, I., Alhakim, M., Moran Velazquez, E., Velasco Sanchez, R., Ortiz, A., Sanchez Diaz, C., Magallanes, G., Nevarez Ruiz, L., Avila, H., Mendez-Machado, G., Grajales, A., Llamas Esperon, G., de la Mora, S., Leiva-Pons, J., Jaramillo, A., Garcia-Castillo, A., Alcantara Colin, M., Garcia, N., Franco Valles, J., Casares Ramirez, M., Delgadillo, T., Carrillo, J., Cardona Munoz, E., Cedano Limon, M., Calvo Vargas, C., Hurtado, A., Bayram Llamas, E., Fujiwara, Y., Kailey, P., Yoshioka, K., Nomura, H., Yoshino, H., Tanaka, K., Yonehara, T., Matsuda, K., Yamashita, T., Takiguchi, M., Yamashina, A., Gao, M., Ito, Y., Yamamoto, Y., Sasaki, S., Yamagishi, T., Yamano, R., Yamada, T., Sakamoto, Y., Yamabe, H., Kuroda, T., Yagi, H., Sato, A., Yagi, M., Sakai, Y., Usuda, K., Onishi, M., Ueyama, Y., Syan, G., Yasumoto, S., Uematsu, M., Terakura, K., Tsuboi, N., Yoshida, K., Tsuboi, H., Nishiya, Y., Tanouchi, J., Uchida, M., Watanabe, E., Takeuchi, S., Yamagishi, K., Takenaka, T., Yahata, A., Takeda, K., Sakurai, Y., Takahashi, T., Kishi, N., Takahashi, A., Takahashi, W., Mohri, S., Takagi, M., Asakura, H., Sumii, K., Miyazaki, E., Sugi, K., Ueda, J., Shoji, Y., Shigenari, M., Shirai, T., Narumi, M., Seino, Y., Fujimoto, E., Satoh, A., Oosawa, N., Sasaki, T., Ooki, H., Sakurai, S., Hayashi, N., Sakuragi, S., Nakano, A., Sakagami, S., Tanikawa, I., Ozaki, Y., Moriyama, H., Onaka, H., Narita, Y., Okumura, K., Kitani, S., Okishige, K., Wada, H., Okazaki, O., Nakashima, M., Okajima, K., Moriyama, Y., Okada, K., Tanabe, M., Oguro, H., Sugeno, M., Ogawa, T., Junko, H., Ochiai, J., Nagase, T., Nishi, Y., Oyama, H., Naito, S., Sakata, Y., Nagai, Y., Murata, J., Munemasa, M., Sakamoto, S., Miyauchi, Y., Kimizu, T., Miyamoto, N., Takeda, M., Mita, T., Satake, M., Meno, H., Ebina, E., Kaneno, Y., Masuyama, T., Koya, E., Kurabayashi, M., Yumoto, I., Koretsune, Y., Tamura, S., Kohno, M., Kikuchi, R., Kobayashi, Y., Igarashi, C., Kitazawa, H., Ichikawa, Y., Kazatani, Y., Ishida, A., Kato, K., Fujii, R., Kamiyama, K., Iida, S., Kamijo, M., Nakahara, F., Kamakura, S., Adachi, C., Kakinoki, S., Nagatome, H., Iwasaki, T., Sakuma, Y., Iwade, K., Ito, T., Itamoto, K., Ise, M., Ishimaru, S., Tomita, H., Ishii, Y., Nozaki, T., Ishibashi, Y., Nakamura, K., Inomata, T., Noguchi, H., Ino, H., Higuchi, K., Iijima, T., Miyamoto, C., Iesaka, Y., Kawaguchi, A., Hirayama, A., Nakagawa, Y., Higashikata, T., Oga, Y., Hiasa, Y., Shimazu, Y., Hashimoto, Y., Nakahara, Y., Haruna, T., Fuki, Y., Harada, K., Kumagai, S., Hara, S., Naganuma, M., Hagiwara, N., Kamitake, C., Furukawa, Y., Yamaguchi, A., Funazaki, T., Fujimoto, C., Fukuda, N., Harada, J., Fukamizu, S., Fujita, T., Ichishita, Y., Fujimoto, K., Omae, K., Fujimoto, S., Kotera, M., Fujii, E., Kozeni, S., Fujii, K., Fujiwara, M., Endo, H., Tsukimine, A., Arakawa, S., Mino, K., Anzai, T., Matsushita, C., Ajioka, M., Masaki, W., Akihisa, U., Hirahara, T., Furiozzi, F., Zaca, V., Gagliano, M., Toschi, V., Breschi, M., Severi, S., Cannoni, S., Rasura, M., Granzow, K., Raisaro, A., Fenu, L., Piseddu, G., Paradiso, G., Pirelli, S., Marciano, C., Filardi, P. Perrone, Lioy, E., Penco, M., Bulgari, M., Metra, M., Babbolin, M., Merlini, P., Francalacci, G., Marino, P., Raggi, F., Lo Pinto, G., Gaggioli, G., Laffi, Laffi, Murena, E., Grassia, V., Bosco, B., Fattore, L., Di Niro, M., Di Pasquale, G., Mazzone, C., Di Lenarda, A., Mariani, M., De Servi, S., De Pace, D., De Caterina, R., Forgione, C., Cuccia, C., Peruzzotti, L., Comi, G., Cervi, E., Boriani, G., Giovannelli, F., Berni, A., Platner, N., Zeltser, D., Kisos, D., Tsalihin, D., Belatsky, V., Swissa, M., Aloni, I., Shochat, M., Sterlin, J., Schiff, E., Logvinenko, S., Rozenman, Y., Givoni, H., Ouzan, E., Karny, M., Lishner, M., Ben Ari, M., Lewis, B., Genin, I., Klainman, E., Majdoub, A., Hayek, T., Roshrosh, M., Hasin, Y., Dagan, T., Grossman, E., Rouwaida, S., Gottlieb, S., Goldhaber, M., Goldhaber, A., Ghantous, R., Francis, A., Ron, G. Avraham, Elias, M., Gilat, T., Lahav, M., Marcoviciu, D., Dicker, D., Lasri, E., Atar, S., Dharmarao, A., Zanwar, I., Thakur, B., Vinod, M. Vijan, Kaur, A., Varma, S., Thankaraj, L., Srinivas, A., Gupta, R., Singh, G., Sudheer, R., Shetty, G., Sethia, S., Sethia, A., Bansal, N., Sethi, K., Singh, R., Sawhney, J., Arora, T., Sarna, M., Jadhav, D., Sant, H., Gadepalli, R., Saha, D., Barai, A., Roy, D., Bekal, S., Reddy, R., Shankar, A. Ravi, Vuriya, A., Rao, M., Jambula, H., Premchand, R., Kharalkar, H., Pinto, B., Babbar, A., Patki, N., Jasani, B., Parekh, P., Sababathi, R., Pandurangi, U., Shams, S., Purayil, M. Padinhare, Angel, J., Gurusamy, P., Oomaan, A., Natarajan, S., Narendra, J., Shelke, S., Namjoshi, D., Francis, V., Menon, J., Sharma, P., Mathur, A., Bhaskarwar, P., Mardikar, H., Kale, M., Lavhe, P., Anthony, A., Kumbla, M., Francis, J., Kumar, A., Karpuram, M., Kumar, P., Lawande, A., Kulkarni, G., Deokar, M., Kulkarni, R., Kotiwale, V., Krishnan, H., Kishore, R., Kandekar, S., Kandekar, B., Raut, N., Kale, V., Joshi, H., Thomas, R., Joseph, J., Oommen, D., Joseph, S., Pahuja, M., Jain, R., Ghume, A., Hiremath, J., Thakor, G., Hardas, S., Savanth, P., Hadan, S., Singh, P., Gupta, J., Saini, A., Goyal, N., Mali, N., Chopda, M., Karnwal, N., Somaraju, B., Calambur, N., Bhuti, M., Biniwale, A., Rathi, A., Bhargava, V., Solanki, R., Bharani, A., Surushe, S., Benjarge, P., Sheth, T., Banker, D., Reddy, J., Babu, R., Rao, B., Babu, P., Shaikh, A., Avvaru, G., Shree, R., Arora, V., Memon, A., Arneja, J., Ranka, R., Agarwal, D., Abdullakutty, J., Malhan, S., Kincses, M., Vertes, A., Marosi, A., Tomcsanyi, J., Szakal, I., Sipos, T., Ruzsa, D., Simor, T., Bognar, A., Sayour, A., Toth, S. Rostasne, Palinkas, A., Nagy, A., Kolumban, E., Merkely, B., Kiss, K., Medvegy, M., Kiss, T., Matoltsy, A., Karakai, H. Horvathne, Lupkovics, G., Kovacs, Z., Baranyai, M., Kovacs, I., Koczka, M., Jakal, A., Kiss, R., Feil, J. Felfoldine, Kis, E., Kosztyu, M., Kanakaridisz, N., Varga, A., Fiok, J., Szatmari, J., Edes, I., Muskoczki, E., Dioszeghy, P., Almaraz, S. Padilla, Camas, L. Velasquez, Guerra, L., Samayoa, C. Sanchez, Pozuelos, J. Mayen, Sanchez, M., Estrada, M. Rodas, Guevara, S., Lavagnino, A. Ovando, Jimenez, T., Melgar, I. Guzman, Ramirez, V. de Leon, Milla, O. Ayau, Korantanis, K., Pyrgakis, V., Kartsagkoulis, E., Olympios, C., Dimitra, K., Moschos, N., Daskalaki, A., Kifnidis, K., Exarchou, E., Karamitsos, C., Tziortziotis, A., Bourlios, P., Mavronasiou, E., Alexopoulos, D., Winter, K., Wolde, C., Buelow-Johansen, B., Winkelmann, B., Weyland, K., Buchholz, M., Voehringer, Voehringer, Ludwig, I., Veltkamp, R., Zarpentin, C., Taggeselle, J., Stoehring, R., Bonin, K., Spitzer, S., Baylacher, M., Sohn, H., Gold, G., Hellmers, J., Schreckenberg, A., Schmidt, M., Schmidt, A., Schiewe, C., Dreykluft, K., Finsterbusch, T., Schenkenberger, I., Frommhold, R., Schellong, S., Szymanowski, N., Schaefer, A., Kuehlenborg, A., Rinke, A., Pilipenko, H., Rack, K., Kuhlmann, M., Proskynitopoulos, N., Pohl, W., Lewinsky, D., Piechatzek, R., Raddatz, K., Mueller-Glamann, M., Barbera, S., Muegge, A., Vogt, S., Mitrovic, V., Frahm, E., Meyer-Pannwitt, U., Braemer, U., Meissner, G., Hoefer, K., Maus, O., Wulf, M., Luttermann, M., Venneklaas, U., Lueders, S., Grosse, B., Lohrbaecher-Kozak, I., Bauch, F., Koenig, H., Meusel, P., Kleinecke-Pohl, U., Schoen, B., Jungmair, W., Schmid, S., Junggeburth, J., Fink, P., Horacek, T., Schuppe, M., Hoffmann, S., Dorn, S., Hoffmann, U., Bobbie, C., Dieckheuer, U., Heuer, H., Peitz, M., Hartmann, A., Otto, A., Grigat, C., Manuela, W., Fuchs, R., Schneider, K., Forck-Boedeker, K., Faghih, M., Herfurth, B., Drescher, T., Kranz, P., Degtyareva, E., Ayasse, D., Daut, W., Kara, M., Contzen, C., Weihrauch, D., Buhr, M., Ladenburger, K., Braun, R., Schnelzer, P., You, Z. G., Bouzo, M., Sehr, B., Beyer-Westendorf, J., Vierbeck, S., Berrouschot, J., Dichristin, U., Bernhardt, P., Wurow, A., Al-Zoebi, A., Duprat, C., Roudaut, R., Leparree, S., Poulard, J., Corbut, S., Kacet, S., Deruche, E., Hermida, J., Arfaoui, M., Dinanian, S., El Jarroudi, M., Decoulx, E., Berger, N., Coisne, D., Dias, P., Blanc, J., Talajic, M., Berbari, H., Belhassane, A., Boyer, M., Babuty, D., Boursin, P., Amarenco, P., El Jarroudi, F., Agraou, B., Le Heuzey, J., Nappila, H., Virtanen, V., Salminen, O., Rasi, H., Sankari, T., Fortin, C., Gilchrist, M., Zondag, M., Dewar, C., Lainesse, A., Roth, M., Viau, C., St-Germain, L., Mucha, M., Lam, S., Lam, H., Lichtenstein, T., Roberts, P., Luton, R., Douglas, S., Ma, P., Seib, M., MacCallum, C., Matthews, J., Malette, P., Vaillancourt, T., Maranda, C., Studenikow, E., Mawji, A., Morely, A., Morrison, D., Nicholson, R., Venkataraman, A., Walker, M., Lamoureux, U., Wright, L., Ebano, P., Storey, R., Price, R., Pye, M., Flint, L., Newby, D., Andrews, A., Murdoch, D., Helliwell, L., Blagden, M., MacCallum, P., Kennard, S., Sopher, M., Young, G., Senior, R., Brown, R., Lip, G., Najarali, A., Dunn, S., More, R., Isted, C., Maxwell, T., Jones, D., Standring, R., Hoag, G., Marazzi, P., McGhee, C., Ho, V., Ho, K., Scott, L., MacLeod, M., O'Hara, G., Heath, J., Finlayson, M., Hatheway, R., Beeton, I., Linker, N., Wright, J., Wright, A., Chung, A., Watkin, R., Atkinson, C., Houbraken, D., Lindsay, S., Turner, W., Ramasamy, V., Lie, F., Avery, D., Bridge, C., Douglas, H., D'Costa, D., Wilmott, R., Duff, J., Huynh, T., Camm, J., Perkins, L., Kouz, S., Roy, M., Labonte, R., Choy, A., Davies, D., Chapman, O., Dougal, K., and Yalcin, R.
- Published
- 2016
34. Stroke and Mortality Risk in Patients With Various Patterns of Atrial Fibrillation: Results From the ENGAGE AF-TIMI 48 Trial (Effective Anticoagulation With Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in Myocardial Infarction 48)
- Author
-
Jones, D., Gu, X. J., Liu, L., Grammer, M., Waseem, M., Roper, E., Harden, M., Zellner, C., Mason, T., Zeig, S., Curtis, S., Zakhary, B., Yousuf, K., Wharton, S., VonGerichten, S., Willis, J., Dowling, C., Williams, R., Gibson, C., Williams, D., Truva, C., Westcott, J., St Laurent, B., Weiss, R., Sanchez, G., Waxman, F., Locklear, T., Ward, S., Renaud, K., Walsh, R., Kilcup, S., Vossler, M., Washam, M., Vijay, N., Warren, K., Vicari, R., Parsons, T., Verma, S., Cardoza, T., Vemireddy, D., Harrelson, K. Gonzalez, Val-Mejias, J., Hanna, K., Updegrove, J., Salas, L., Tucker, P., Romero, N., Torres, M., Southam, D., Teixeira, J., Mitchell, T., Tee, H., Young, K., Teague, S., Dastoli, K., Tawney, K., Swauger, M., Tatarko, M., Corchado, D., Tami, L., Leo, L., Talano, J., Bruton, T., Takata, T., Springer, K., Tahirkheli, N., Herwehe, S., Szulawski, I., Freemyer, D., Swerchowsky, V., Frost, J., Suresh, D., Vittitow, T., Struble, R., Cox, C., Steljes, A., Liu, M., Staniloae, C., McCartney, P., Spivack, E., Vasquez, E., Sperling, M., Thomason, L., Spangenthal, S., Hodnett, P., Smith, R., Keene, R., Smith, S., Hughes, B., Skierka, R., Nelson, M., Singh, V., Turner, K., Singh, N., Meyer, R., Simpson, P., Champagne, M., Siler, T., Stephenson, L., Shoukfeh, M., Browning, J., Shih, H., Hengerer, T., Sheikh, K., Hren, A., Shaoulian, E., Fleets, J., Shanes, J., Seese, M., Shalaby, A., Witt, P., Shah, G., Mather, N., Seide, H., Holt, A., Ullig, T., Seals, A., Mercer, S., Schulman, D., Schneider, W., Schneider, R., Fekete, A., Schaefer, S., Clifton, R., Savin, V., Lafave, J., Sandberg, J., Schomburg, J., Samal, A., Ball, E., Sacco, J., Nelson, T., Ruoff, G., Freeman, R., Ross, S., Martin, C., Rosen, R., Barnhorst, M., Rosado, J., Hollihan, P., Roehll, W., Cherrico, M., Robinson, J., Braun, D., Riofrio, K., Roberts, J., Pazier, P., Richwine, R., Stanley, E., Renzi, M., Wroblewski, J., Redondo, V., Domingo, D., Rama, P., Hemmen, C., Quinn, J., Reed, C., Quinlan, E., Rafla, E., Quadrel, M., Ebert, J., Pugeda, J., Sham, L., Pudi, K., Lowe, K., Pribble, A., Neeper, L., Pratt, R., Cush, S., Poulathas, A., Kirk, D., Yovaniniz, P., Pezzella, S., Brown, F., Pettis, K., Morlando, F., Petruzziello, F., Chacon, L., Peters, P., Duncan, D., Pentz, W., Montayne, S., Pearlstein, R., Gorry, N., Pavon, H., Dennison, K., Patnam, S., Joseph, L., Oza, S., Gonzalez, M., Osborne, J., Garcia, L., Orchard, R., McCormick, J., Oppenheimer, K., Thakkar, N., Oberoi, M., Wilmot, M., Nielsen, R., Nomanee, S., Nguyen, T., Goza, J., Nallasivan, M., West, M., Naidu, J., Parker, A., Nadar, V., Oehmann, V., Murphy, A., Raziano, S., Mullen, P., Todd, S., Mowdy, M., Schuler, C., Mounsey, P., Parrott, N., Mouhaffel, A., Bowman, B., Morledge, J., Garner, S., Moran, J., Strugatsky, S., Mody, F., Gryczan, J., Miller, S., Sanchez, S., Miller, R., Sanders, D., Milas, J., Romero-Colon, J., Michlin, B., Cajulis, C., Mercado, A., Cervellione, K., Mendelson, R., Wall, J., Mehrle, A., Skinner, J., Meholick, A., Marti, J., Mega, J., Lack, A., McLaurin, B., Paul, J., McKnight, T., Rodkey, K., McKenzie, M., Miranda, J., McGuire, K., Schwarz, L., McGarvey, J., Stubbs, L., McCartney, M., Hicks, T., Massin, E., Bedenko, E., Marenberg, M., Rabadi-Marar, D., Marar, I., Hernandez, S., Mandviwala, M., Casas, R., Makam, S., Lisiecki, B., Mainigi, S., Doctor, A., Magee, A., Bush, D., Macomber, J., Edelstein, J., Lurie, M., Wright, H., Lui, H., Ault, S., Looby, R., Davids, M., Lone, B., Shah, D., Lomnitz, D., Wofford, E., Littlefield, R., Murphy, R., Ling, L., Miller, D., Lillestol, M., Bonds, C., Lewis, D., Hartley, L., Lesser, M., Smith, D., Lentz, M., Royse, H., Ledbetter, L., Faucett, S., Langevin, E., Simmons, T., Lang, J., Ferguson, D., Landau, C., Coyle, G. Stagi, Lambert, C., Jauregui, V., Laliotis, A., Marquez, D., Krichmar, P., Watts, S., Kozlowski, J., Sanchez, E., Kotha, P., Godfrey, C., Korpas, D., Averett, P., Kindman, L., Khan, G., Khan, M., Binns, M., Khan, B., DiCorcia, L., Kesselbrenner, M., Buhler, A., Kersh, R., Bartholomaus, D., Kerkering, M., Keller, J., Keller, R., Davis, C., Kastelic, R., Behm, K., Karunaratne, H., Ruggiero, M., Kapoor, A., Cook, S., Kaplan, K., Kostedt, G., Kandath, D., Dugal, J., Kai, W., Coombs, V., Kahn, B., Royes, A., Judson, P., Nichols, M., Jovin, I., Hughett, G., Jones, R., Phillips, T., Johnson, F., Andresen, T., Jardula, M., Butcher, S., Ison, R., Tambawala, M., Hussain, M., Garza, M., Hurst, P., Battistelli, E., Hunter, J., Huang, P., Craft, D., Howard, L., Hays, D., Howard, V., Adams, K., Houchin, V., Caterini, T., Turner, N., Hotchkiss, D., Sloss, D., Horton, K., Homayouni, A., Homan, J., Young, C., Hoekstra, J., Dutter, S., Hippert, R., Vieira, P., Hinchman, D., Carey, G., Herson, S., Miranda, D., Herrod, J., Batchell, K., Hermany, P., Harkins, V., Henry, S., Millard, D., Henderson, D., Dandekar, U., Heiman, M., Krater, C., Hearne, S., Bobade, M., Harris, J., Cavanna, L., Han, M., Bentivenga, L., Hamroff, G., Morelli, L., Hack, T., McLean, R., Gvora, T., Felsman, D., Guthrie, R., Foster, B., Guerrero, Guerrero, Fisher, M., Guarnieri, T., Gabela, W., Guarino, J., Mabe, K., Grove, D., Davis, A., Grossman, C., Goodman, V., Griffin, J., Aull, L., Griffin, S., Bonora, M., Graham, S., Rafala, E., Gowda, S., Goldstein, M., Latteri, J., Goldscher, D., Ewing, B., Gogia, H., Keane-Richmond, P., Gillespie, E., Hinchion, N., Gerber, J., Valentine, H., George, F., Garb, J., Jones, J., Gaffney, M., Smith, K., Friedlander, I., Morales, C., French, W., Gentry, P., Franco, M., Thrope, C., Frais, M., Solis, A., Forman, S., Slayton, C., Flores, E., Woodford, T., Zhang, Z., Lin, Y. N., Rupka, D., Donahue, S., Fishbein, G., Drew, B., Fischell, T., Zhang, H. Q., Lim, G., Finkelstein, S., Shriver, D., Finkel, M., Calvo, M., Fialkow, J., Prior, J., Felten, W., Tang, N., Feldman, J., Tameron, A., Feld, L., Watkins, D., Fahmy, R., DeSalle, D., Everhart, B., Shipp, A., Ettinger, N., O'Brien, J., Johnson, C., Qiang, H., Erenrich, N., Cristaldi, J., Ellis, J., Quick, R., Eldadah, Z., Dunn, K., Eade, J., Cullen, T., D'Souza, A., Habibi, S., Drozdiak, R., Olson, A., Dotani, I., Rodriguez, L., Donovan, D., Tisdale, L., DiGiovanna, M., Ucik, S., Dhar, S., Briscoe, C., Devenport, S., Waters, L., Desire, A., Steward, A., Desai, A., Carey, J., DeGarmo, R., Warmack, D., Dean, J., Debes, C., De Lemos, J., Ebreo, N., Davuluri, A., Dave, B., Dave, K., Wulf, A., Datta, S., Leka, G., Daniels, S., Morgan, T., Dang, N., Sarpola, N., Curtis, B., Nelson, L., Cowan, L., Masson, E., Cottiero, R., Mullinax, K., Cossu, S., Svadbik, L., Corbett, B., Martinez, E., Concha, M., Cole, J., Salpas, S., Colan, D., Bossaers, J., Cohen, R., Dutka, C., Cohen, A., McClelland, M., Clay, A., Clapp, T., Bagby, J., Ciaramita, J., Sawaya, K., Chaturvedi, S., Tamayo, M., Charlat, M., Hatfield, G., Chang, M., Phan, D., Carr, K., Jameson, L., Caplan, J., Hartranft, E., Canosa, R., Dickinson, D., Canaday, D., Morton, S., Cader, C., Al-Maliky, T., Bybee, K., Triano, A., Brown, H., Frey, W., Brilakis, E., Terry, P., Bradley, A., Ziegler, K., Bowden, W., Wade, W., Bouchard, A., Hickenbotham, D., Borsheim, M., Vernon, M., Blue, B., Bloomberg, K., Bloomberg, R., Ensminger, E., Blonder, R., Talbot-Lawson, C., Block, T., Antonino, M., Bingham, S., Langone, L., Bilazarian, S., Marchand, C., Preston, S., Bilal, B., Eldred, R., Bernard, J., Ibarra, M., Berk, M., Garman, V., Bensimhon, D., Swaim, D., Beinart, S., Craig, M., Bedwell, N., Luis-Valdes, M., Bedoya, R., Hoffman, T., Beasley, R., Benton, J., Bartkowiak, A., Gordon, L., Barrington, P., Faircloth, C., Barker, T., Altonen, D., Barber, M., Campbell, G., Baman, R., Batista, M., Baine, S., Thompson, B., Ayesu, K., Baldwin, E., Awasty, V., Cobos, D., Aude, Y., Strickland, S., Attanti, S., Rasmussen, L., Arouni, A., Shoaf, R., Arnold, T., York, T., Anderson, J., Persechino, F., Amin, M., Khetarpal, S., Amin, K., Lane, B., Alsheikh, T., MacDonald, H., Almquist, A., Biscardi, R., Allison, J., Godsey, W., Aliyar, P., Genova-Peeva, E., Alexander, J., Brubaker, S., Akhter, F., Ahmadpour, H., Hussain, A., Ahmad, A., Beck, P., Aggarwal, R., Reiling, S., Adler, P., Barash, B., Adler, J., Lohman, J., Panella, M., Abi-Mansour, P., Mackin, A., Moriarty, A., Green, M., Shandra, T., Zhurba, S., Logvinov, Y., Zharinov, O., Mudruk, I., Yena, L., Nahrebetskyy, V., Yagensky, A., Serik, S., Volkov, V., Goncharov, O., Vizir, V., Sklyanna, O., Vatutin, M., Drapchak, I., Vakaliuk, I., Tykhonova, S., Kuznetsov, I., Tseluyko, V., Lyzohub, S., Sychov, O., Perebetiuk, L., Stanislavchuk, M., Sirenko, Y., Zamlynskyy, M., Shvetz, N., Goncharova, I., Shcherbak, V., Ishchuk, V., Shatilo, V., Rudyk, I., Chendey, T., Rishko, M., Gamachek, O., Rebrov, B., Leonidova, V., Prokhorov, O., Nekrasa, A., Potapenko, P., Dovgan, N., Parkhomenko, A., Ushakova-Sokolova, L., Ostrovska, L., Fedotov, S., Malynovsky, Y., Gorna, O., Lizogub, V., Kyyak, Y., Kupnovytska, I., Stets, R., Kraydashenko, O., Usan, N., Kraiz, I., Kaplan, P., Koval', O., Ohirko, O., Koval, V., Dvoieglazova, M., Kotseruba, V., Petyunina, O., Kopytsya, M., Vasylets, V., Kolomyyits, S., Gerasimenko, N., Kaydashev, I., Blihar, O., Karpenko, Y., Nevolina, I., Karpenko, O., Samburg, Y., Godlevska, O., Husyev, V., Horbach, L., Dzublik, Y., Gavrysyuk, V., Sorokivskyy, M., Faynyk, A., Vasilyeva, L., Dzyak, G., Kulynych, R., Dotsenko, S., Lebedynskaya, M., Bereznyakov, I., Vlasyuk, Z., Bazylevych, A., Azhdari, M., Batushkin, V., Zoghi, M., Yigit, Z., Yigit, F., Tandogan, I., Turgut, O., Oto, A., Kanadasi, M., Kabul, K., Ermis, C., Erdogan, D., Ceyhan, C., Cayli, M., Calik, A., Cakmak, N., Bayata, S., Ata, N., Demir, H., Akilli, H., Acikel, M., Vorasettakarnkij, Y., Mekara, W., Sukonthasarn, A., Panpunuan, P., Sritara, P., Sripracha, A., Piyayotai, D., Bamrungpong, P., Laothavorn, P., Sriprasert, S., Kiatchoosakun, S., Sinthusopa, W., Kaewsuwanna, P., Pornchaiyasit, K., Jirasirirojanakorn, K., Kuo, J. Y., Yeh, H. I., Tsai, W. C., Wang, J. H., Lee, S. C., Ueng, K. C., Pan, Y. F., Tseng, W. K., Chiu, C. Z., Shyu, K. G., Lin, K. H., Pai, P. Y., Lee, J. T., Lin, T. H., Lai, W. T., Wang, C. L., Kuo, C. T., Mabee, J., Chen, Y. F., Huang, J. L., Chen, Y. P., Hsia, C. H., Yeh, T. C., Chiou, C. W., Wu, Y. W., Chiang, F. T., Yu, W. C., Chiang, C. E., Wu, W. S., Cheng, C. C., Slater, I. Petrova, Moccetti, T., Broberg, M., Thulin, J., Gunnarsson, A., Stenberg, A., Sundholm, C., Ronn, F., Johansson, M., Rautio, A., Moodh, J., Randers, F., Eriksson, G., Malmqvist, L., Edlund, M., Kozak, P., Hakansson, E., Koskinen, P., Jernhed, H., Juul-Moller, S., Winberg, L., Herlitz, J., Karlsson, L., Engdahl, J., Ostberg, S., Dettmann, S., Bengtsson, A. Stener, Carlsson, T., Persson, L., Blomstrom, P., Andersson, R., Blom, K. Berndtsson, Akerberg, A., Appelros, P., Astier, L., Villuendas, R., Dachs Delgado, M., Terns, M., Fernandez Alvarez, R., Fernandez, M., Arias, J., Diaz-Pintado, M., Merino, J., Blanco Abril, S., Manzano, L., Barquero, R., Lopez Garcia-Aranda, V., Delgado, A., Hernandez Madrid, A., Moure, M., Gonzalez Juanatey, J., Perez Guevara, M., Diez Tejedor, E., Asensio, A., De Arce Borda, A., Calvo, G., Calvo, C., Cabero, P., Bruguera Cortada, J., Puertas, I., Blanco Coronado, J., Manzanal Rey, A., Arcocha Torres, M., Kim, J. Y., Rim, S. J., Na, J. O., Rha, S. W., Kwak, J. J., Namgung, J., Shin, D. G., Lee, S. H., Joung, B. Y., Lee, M. H., Chun, M. Y., Kim, Y. J., Seo, J. B., Kim, S. H., Park, S. J., Kim, J. S., Park, J. H., Kim, J. H., Park, M. S., Kim, J. T., Cha, M. J., Kim, H. S., Seo, J. S., Kim, D. S., Jin, E. S., Kim, C. J., Choi, K. J., Kang, D. H., Lee, J. M., Jeon, H. K., Jung, J. W., Hyon, M. S., Lee, H. W., Hong, T. J., Lee, K. H., Han, S. H., Oh, Y. S., Chung, W. S., Hong, K. S., Choi, H. H., Ryu, D. R., Cho, B. R., Kim, D. H., Cha, J. K., Han, M. G., Bae, H. J., Wessels, L., Venter, T., Le Roux, M., Van Zyl, L., Goosen, Y., Van Der Merwe, N., Johnston, H., Soma, P., Munnik, M., Snyders, F., Duki, Y., Naidoo, D., Taljaard, J., Mitha, I., Kelfkens, Y., Wilson, L., Gani, M., Nunkoo, T., Essop, M., Mostert, M., Engelbrecht, J., Botha, L., Ellis, G., Allman, J., Dalby, A., Poynton, M., Basson, M., Erasmus, L., Badenhorst, J., Bollova, D., Zareczky, P., Kokles, M., Zachar, A., Kmec, J., Slanina, M., Morsky, J., Ruffini, L., Fedacko, J., Pella, D., Mazur, J., Reptova, A., Kasperova, V., Hofmanova, J., Hranai, M., Hatala, R., Hatalova, K., Dzupinova, M., Dzupina, A., Vankova, L., Duris, T., Dulka, T., Dulkova, K., Kosmalova, V., Dukat, A., Banikova, A., Ambrovic, I., Ambrovicova, V., Tesic, M., Golshmid, M., Ruda, M., Topolnitchi, O., Castro, C., Ostojic, M., Tesic, B. Vujisic, Mitrovic, P., Vasiljevic-Pokrajcic, Z., Davicevic, Z., Tavciovski, D., Milinkovic, I., Seferovic, P., Kalezic, T., Putnikovic, B., Polovina, M., Potpara, T., Tasic, N., Otasevic, P., Djokic, I., Miloradovic, V., Djokovic, A., Krotin, M., Ilic, B., Ilic, S., Erceg, P., Despotovic, N., Bjelobrk, M., Adjic, N. Cemerlic, Majstorovic, A., Celic, V., Djordjevic-Radojkovic, D., Apostolovic, S., Motylev, I., Zubeeva, G., Kononenko, O., Zenin, S., Mankhaeva, B., Zateyshchikova, A., Zotova, I., Zateyshchikov, D., Nikulina, N., Yakushin, S., Petrochenko, A., Yakusevich, V., Rodina, N., Volkov, D., Kirgizova, A., Vishnevsky, A., Rossovskaya, M., Ustyugov, S., Bulygin, S., Timofeev, A., Solovyev, A., Tikhonova, E., Kositsyna, I., Tereshenko, S., Isakov, L., Tarasov, N., Gonzales, C., Dronov, D., Suprun, E., Erofeeva, S., Sobolev, K., Lapidus, N., Sizova, Z., Orlov, V., Sinitsina, I., Vorontsova, S., Sidorenko, B., Agirov, M., Shogenov, Z., Lebedev, E., Shaposhnik, I., Repin, M., Karoli, N., Rebrov, A., Letaeva, M., Raskina, T., Pikalova, N., Poluyanova, N., Matveeva, I., Polkanova, E., Nilk, R., Panov, A., Laguta, P., Panchenko, E., Patrusheva, S., Novikova, N., Khromova, O., Nikolskaya, I., Nikolaev, A., Nikolaev, K., Lamden, D., Lukyanov, Y., Belousova, L., Lila, A., Moiseeva, Y., Libov, I., Maslova, A., Libis, R., Volkova, E., Levashov, S., Tereschenko, L., Lavrova, O., Rychkov, A., Kuznetsov, V., Kostenko, O., Kozyrev, O., Polyanskaya, E., Koziolova, N., Karabalieva, S., Kostenko, V., Khrustalev, A., Khrustalev, O., Tsareva, E., Khokhlov, R., Sinitsina, O., Khokhlov, A., Kireenkov, I., Khirmanov, V., Kosenko, B., Buza, V., Karpov, Y., Mazovets, O., Gratsiansky, N., Laptev, I., Goloshchekin, B., Kratskina, T., Golitsyn, S., Valovyeva, S., Glezer, M., Valuyshkih, E., Gilinskaya, O., Soin, I., Filatov, A., Kirichek, N., Esip, V., Egorova, L., Zyatenkova, E., Drapkina, O., Puchinyan, N., Dovgalevsky, P., Masin, A., Demko, A., Pokutneva, O., Chumakova, G., Khlevchuk, T., Bokarev, I., Yukhno, E., Berns, S., Kosolapov, Y., Belenky, D., Larina, V., Bart, B., Bashkireva, A., Barbarash, O., Alexandrova, L., Ballyuzek, M., Chernyavskaya, T., Arutyunov, G., Zhukova, N., Tudoran, C., Tudoran, M., Topolnitchi, L., Spinu, C., Stamate, S., Plosca, P., Sipciu, D., Ardelean, A., Popescu, M., Cozma, M., Pop, C., Serban, D., Minescu, B., Costache, L., Iosipescu, L., Jurca, S., Dragomir, D., Sirbu, I., Dobreanu, D., Voicu, O., Kang, H., Dobre, I., Jemna, D., Crisu, D., Anciu, M., Cristea, M., Parasteac, M., Creteanu, M., Constantinescu, M., Ghionea, M., Coman, I., Andor, M., Ciobotaru, G., Bolohan, F., Doka, B., Bobescu, E., Ochean, V., Bengus, C., Badila, E., Bartos, D., Matei, C., Apetrei, E., Ciortea, M., Albulescu, P., Soares, D., Santos, J., Veiga Pais Nunes, L., Santos, O., Goncalves, A., Salgado, A., Leitao Marques, A., Oliveira, D., Monteiro, P., Neves, E., Martins, D., Maymone, D., Madeira, J., Lopes, S., Gil, V., Correia, J., Matias, F., Nawrot, M., Zielinski, M., Krauze, R., Zarebinski, M., Kudlicki, J., Wysokinski, A., Muzalewski, P., Wrobel, W., Turbak, R., Malanska, A., Szolkiewicz, M., Spyra, J., Sendrowski, D., Norwa-Otto, B., Ruzyllo, W., Ronkowski, R., Rozmyslowicz-Szerminska, W., Rewinska, H., Zienciuk-Krajka, A., Raczak, G., Bojanowska, E., Polaszewska-Pulkownik, V., Pogorzelska, H., Janczewska, D., Podjacka, D., Olszewski, M., Nowak, J., Nej, A., Niezgoda, K., Nessler, B., Nessler, J., Biniek, D., Napora, P., Myslinski, W., Mosiewicz, J., Kosmalska, K., Miekus, P., Chmielowski, A., Mazur, S., Meissner, G., Kosmaczewska, A., Wnetrzak-Michalska, R., Sznajder, R., Matyszczak-Toniak, L., Jaguszewska, G., Lysek, R., Szymanska, K., Lubinski, A., Stopyra-Poczatek, M., Lewczuk, J., Wierzykowski, T., Lesnik, J., Kus, W., Sklodowskiej-Curie, M., Muzyk-Osikowicz, M., Krzyzanowski, W., Borowski, W., Korzeniak, R., Benicka, E., Konieczny, M., Kaliszczak, R., Karczmarczyk, A., Tymendorf, K., Kania, G., Kaminski, L., Pacholska, A., Kaczmarek, B., Jurowiecki, J., Ciezak, P., Jazwinska-Tarnawska, E., Makowiecka-Ciesla, M., Januszewicz, A., Mroczkowski, P., Gniot, J., Zajac, E., Gieroba, A., Guziewicz, M., Domanska, E., Laskowska-Derlaga, E., Derlaga, B., Ptak, A., Dabrowska, M., Cymerman, K., Krzystolik, A., Busz-Papiez, B., Cieslak, B., Bronisz, M., Baszak, J., Korzeniowska-Adamus, J., Adamus, J., Nario, K., Villamor, L., Aquino, M., To, R., Gilo, L., Roxas, A., Joaquin, F., Rogelio, G., Enad, C., Matiga, G., Vallenas, M., Coching, R., Zapanta, M., Barcinas, R., Sambaz, C. M., Babilonia, N., Delgado, S., Sanchez Vallejo, G., Horna, M., Yanac Chavez, P., Fernandez Rodriguez, K., Torres, P., Rodriguez, A., Honores Armas, B., Negron Miguel, S., Bautista, C., Minchola, J., Rodriguez, J., Medina Palomino, F., Araoz Bedregal, S., Llerena, N., Carrion, A., Lema, J., Luna, C., Chavez, C., Esteves Mendoza, R., Cabrera, J., Tejada Guillen, M., Bustamante, G., Enger, S., Tveit, A., Thunhaug, H., Sandvik, J., Melbue, R., Hofsoy, K., Claussen, H., Atar, D., Kennett, K., Skelton, L., Troughton, R., Cammell, R., Scott, D., Turner, A., Hart, H., Tomlinson, J., Hamer, A., Green, B., Monkley, R., Fisher, R., Lara Lara, C., Copley, M., Doughty, R., Shu, D., Borthwick, L., White, H., Benatar, J., Kjentjes, M., O'Meeghan, T., Anscombe, R., Hofmeyer, H., van der Heijden, D., Mevissen, H., Kooiman, E., Mannaerts, H., Muijs, L., Kietselaer, B., Daniels, R., Hazeleger, R., de Vos, R., Radder, I., de Groot, J., Buiks, C., Jones, A., Bruning, T., van Welsen, I., Alhakim, M., Moran Velazquez, E., Velasco Sanchez, R., Ortiz, A., Sanchez Diaz, C., Magallanes, G., Nevarez Ruiz, L., Avila, H., Mendez-Machado, G., Grajales, A., Llamas Esperon, G., de la Mora, S., Leiva-Pons, J., Jaramillo, A., Garcia-Castillo, A., Alcantara Colin, M., Garcia, N., Franco Valles, J., Casares Ramirez, M., Delgadillo, T., Carrillo, J., Cardona Munoz, E., Cedano Limon, M., Calvo Vargas, C., Hurtado, A., Bayram Llamas, E., Fujiwara, Y., Yoshioka, K., Nomura, H., Yoshino, H., Tanaka, K., Yonehara, T., Matsuda, K., Yamashita, T., Takiguchi, M., Yamashina, A., Ito, Y., Yamamoto, Y., Sasaki, S., Yamagishi, T., Yamano, R., Yamada, T., Sakamoto, Y., Yamabe, H., Kuroda, T., Yagi, H., Sato, A., Yagi, M., Sakai, Y., Usuda, K., Onishi, M., Ueyama, Y., Yasumoto, S., Uematsu, M., Terakura, K., Tsuboi, N., Yoshida, K., Tsuboi, H., Nishiya, Y., Tanouchi, J., Uchida, M., Watanabe, E., Takeuchi, S., Yamagishi, K., Takenaka, T., Yahata, A., Takeda, K., Sakurai, Y., Takahashi, T., Kishi, N., Takahashi, A., Takahashi, W., Mohri, S., Takagi, M., Asakura, H., Sumii, K., Miyazaki, E., Sugi, K., Ueda, J., Shoji, Y., Shigenari, M., Shirai, T., Narumi, M., Seino, Y., Fujimoto, E., Satoh, A., Oosawa, N., Sasaki, T., Ooki, H., Sakurai, S., Hayashi, N., Sakuragi, S., Nakano, A., Sakagami, S., Tanikawa, I., Ozaki, Y., Moriyama, H., Onaka, H., Narita, Y., Okumura, K., Kitani, S., Okishige, K., Wada, H., Okazaki, O., Nakashima, M., Okajima, K., Moriyama, Y., Okada, K., Tanabe, M., Oguro, H., Sugeno, M., Ogawa, T., Junko, H., Ochiai, J., Nagase, T., Nishi, Y., Oyama, H., Naito, S., Sakata, Y., Nagai, Y., Murata, J., Munemasa, M., Sakamoto, S., Miyauchi, Y., Kimizu, T., Miyamoto, N., Takeda, M., Mita, T., Satake, M., Meno, H., Ebina, E., Kaneno, Y., Masuyama, T., Koya, E., Kurabayashi, M., Yumoto, I., Koretsune, Y., Tamura, S., Kohno, M., Kikuchi, R., Kobayashi, Y., Igarashi, C., Kitazawa, H., Ichikawa, Y., Kazatani, Y., Ishida, A., Kato, K., Fujii, R., Kamiyama, K., Iida, S., Kamijo, M., Nakahara, F., Kamakura, S., Adachi, C., Kakinoki, S., Nagatome, H., Iwasaki, T., Sakuma, Y., Iwade, K., Ito, T., Itamoto, K., Ise, M., Ishimaru, S., Tomita, H., Ishii, Y., Nozaki, T., Ishibashi, Y., Nakamura, K., Inomata, T., Noguchi, H., Ino, H., Higuchi, K., Iijima, T., Miyamoto, C., Iesaka, Y., Kawaguchi, A., Hirayama, A., Nakagawa, Y., Higashikata, T., Oga, Y., Hiasa, Y., Shimazu, Y., Hashimoto, Y., Nakahara, Y., Haruna, T., Fuki, Y., Harada, K., Kumagai, S., Hara, S., Naganuma, M., Hagiwara, N., Kamitake, C., Furukawa, Y., Yamaguchi, A., Funazaki, T., Fujimoto, C., Fukuda, N., Harada, J., Fukamizu, S., Fujita, T., Ichishita, Y., Fujimoto, K., Omae, K., Fujimoto, S., Kotera, M., Fujii, E., Kozeni, S., Fujii, K., Fujiwara, M., Endo, H., Tsukimine, A., Arakawa, S., Mino, K., Anzai, T., Matsushita, C., Ajioka, M., Masaki, W., Akihisa, U., Hirahara, T., Furiozzi, F., Zaca, V., Gagliano, M., Toschi, V., Breschi, M., Severi, S., Cannoni, S., Rasura, M., Granzow, K., Raisaro, A., Fenu, L., Piseddu, G., Paradiso, G., Pirelli, S., Marciano, C., Filardi, P. Perrone, Lioy, E., Penco, M., Bulgari, M., Metra, M., Babbolin, M., Merlini, P., Francalacci, G., Marino, P., Raggi, F., Lo Pinto, G., Gaggioli, G., Laffi, Laffi, Murena, E., Grassia, V., Bosco, B., Fattore, L., Di Niro, M., Di Pasquale, G., Mazzone, C., Di Lenarda, A., Mariani, M., De Servi, S., De Pace, D., De Caterina, R., Forgione, C., Cuccia, C., Peruzzotti, L., Comi, G., Cervi, E., Boriani, G., Giovannelli, F., Berni, A., Platner, N., Zeltser, D., Kisos, D., Tsalihin, D., Belatsky, V., Swissa, M., Aloni, I., Shochat, M., Sterlin, J., Balboa, W., Schiff, E., Logvinenko, S., Rozenman, Y., Givoni, H., Ouzan, E., Karny, M., Lishner, M., Ben Ari, M., Lewis, B., Genin, I., Klainman, E., Majdoub, A., Hayek, T., Roshrosh, M., Hasin, Y., Dagan, T., Grossman, E., Rouwaida, S., Gottlieb, S., Goldhaber, M., Goldhaber, A., Ghantous, R., Francis, A., Ron, G. Avraham, Elias, M., Gilat, T., Lahav, M., Marcoviciu, D., Dicker, D., Lasri, E., Atar, S., Dharmarao, A., Zanwar, I., Thakur, B., Vinod, M. Vijan, Kaur, A., Varma, S., Thankaraj, L., Stockins, B., Srinivas, A., Gupta, R., Singh, G., Sudheer, R., Shetty, G., Sethia, S., Yuan, Z. Y., Sethia, A., Bansal, N., Sethi, K., Singh, R., Sawhney, J., Arora, T., Li, L. L., Sarna, M., Jadhav, D., Sant, H., Gadepalli, R., Saha, D., Barai, A., Roy, D., Bekal, S., Reddy, R., Shankar, A. Ravi, Vuriya, A., Yu, B., Rao, M., Jambula, H., Premchand, R., Kharalkar, H., Pinto, B., Babbar, A., Bozek, B., Patki, N., Jasani, B., Parekh, P., Sababathi, R., Pandurangi, U., Shams, S., Purayil, M. Padinhare, Angel, J., Gurusamy, P., Oomaan, A., Natarajan, S., Narendra, J., Shelke, S., Namjoshi, D., Francis, V., Menon, J., Sharma, P., Mathur, A., Ricci, J., Nethercott, C., Bhaskarwar, P., Mardikar, H., Kale, M., Lavhe, P., Anthony, A., Kumbla, M., Qureshi, A., Francis, J., Turri, L., Polasek, P., Sardin, V., Pesant, Y., Kumar, A., Karpuram, M., Kumar, P., Lawande, A., Kulkarni, G., Deokar, M., Carroll, L., Quintero, A., Morley, A., Parkash, R., Kranz, P., Drescher, T., Kulkarni, R., Kotiwale, V., Krishnan, H., Kishore, R., Kandekar, S., Kandekar, B., Raut, N., Kale, V., Wahby, R., Joshi, H., Thomas, R., Herfurth, B., Faghih, M., Forck-Boedeker, K., Schneider, K., Sohn, H., Baylacher, M., Joseph, J., Li, W. M., Oommen, D., Joseph, S., Pahuja, M., Jain, R., Ghume, A., Hiremath, J., Thakor, G., Hardas, S., Savanth, P., Li, L., Hadan, S., Singh, P., Fuchs, R., Gupta, J., Saini, A., Manuela, W., Grigat, C., Liu, B., Liu, H., Otto, A., Hartmann, A., Goyal, N., Peitz, M., Grandon Azua, M., Bai, F., Heuer, H., Xu, G. L., Dieckheuer, U., Chen, J. Z., Mali, N., Chopda, M., Karnwal, N., Somaraju, B., Calambur, N., Bhuti, M., Biniwale, A., Rathi, A., Bhargava, V., Solanki, R., Bharani, A., Surushe, S., Silverio, G., Benjarge, P., Sheth, T., Banker, D., Reddy, J., Babu, R., Rao, B., Babu, P., Shaikh, A., Avvaru, G., Shree, R., Arora, V., Memon, A., Zhao, R. P., Arneja, J., Ranka, R., Agarwal, D., Abdullakutty, J., Malhan, S., Kincses, M., Vertes, A., Marosi, A., Tomcsanyi, J., Szakal, I., Sipos, T., Ruzsa, D., Simor, T., Bognar, A., Sayour, A., Toth, S. Rostasne, St-Hilaire, R., Palinkas, A., Nagy, A., Kolumban, E., Merkely, B., Kiss, K., Medvegy, M., Kiss, T., Matoltsy, A., Karakai, H. Horvathne, Lupkovics, G., Kovacs, Z., Baranyai, M., Kovacs, I., Koczka, M., Jakal, A., Kiss, R., Feil, J. Felfoldine, Kis, E., Kosztyu, M., Kanakaridisz, N., Varga, A., Fiok, J., Szatmari, J., Edes, I., Muskoczki, E., Dioszeghy, P., Almaraz, S. Padilla, Camas, L. Velasquez, Guerra, L., Samayoa, C. Sanchez, Pozuelos, J. Mayen, Sanchez, M., Estrada, M. Rodas, Guevara, S., Lavagnino, A. Ovando, Jimenez, T., Melgar, I. Guzman, Ramirez, V. de Leon, Milla, O. Ayau, Korantanis, K., Pyrgakis, V., Kartsagkoulis, E., Olympios, C., Dimitra, K., Moschos, N., Daskalaki, A., Kifnidis, K., Exarchou, E., Karamitsos, C., Tziortziotis, A., Bourlios, P., Mavronasiou, E., Alexopoulos, D., Winter, K., Wolde, C., Buelow-Johansen, B., Winkelmann, B., Weyland, K., Buchholz, M., Viau, C., Fortin, C., Zondag, M., Eikelboom, J., Krider, J., Dufresne, M., Kubanska, A., du Preez, M., Denis, I., Coutu, B., Masson, C., Costi, P., Gauthier, M., Constance, C., Valley, S., Cleveland, D., Vansickle, L., Chilvers, M., Lepage, C., Chehayeb, R., Otis, J., Cha, J., Hundseth, M., Bose, S., Stafford, C., Bhargava, R., Antle, S., Archibald, J., Manoylov, E., Kitova, M., Tzekova, M., Braemer, U., Tumbeva, D., Perdomo Mejia, I., Tumbev, H., Nyagina, M., Todorov, G., Momchilova-Lozeva, D., Staneva, A., Vasilev, I., Popov, A., Milusheva, T., Petranov, S., Kostov, K., Pencheva, G., Vasilev, D., Nikolov, F., Stoyanovski, V., Mincheva, V., Miteva, B., Mihov, A., Manolova, A., Kamenova, P., Hergeldjieva, V., Kinova, E., Goudev, A., Kostova, E., Georgiev, B., Gergova, V., Donova, T., Milcheva, N., Denchev, S., Parishev, G., Chompalova, B., Zimmermann, E. Burger, Zimmermann, S., Almeida, M., Boas, F. Villas, Lustosa, E., Sobral Filho, D., Carraro, A., Simoes, M., Vicente, C., Saraiva, J., do Val, R., Sampaio, R., Pagnan, L. Goncalves, dos Santos, F. Rossi, Rodrigues, D., Rodrigues, A., Rocha, M. Rubia, Rodrigues, L., Xu, Y. P., Barros, R., Rocha, J., Leipelt, J., Katz Weiand, L. Reis, Gold, G., Avellar, K., Reis, G., Gozalo, A., Almeida, J. Pimenta, Luiz, R. Osorio, Leaes, P., Morales, K., Sebba Barroso de Souza, W. Kunz, Radaelli, G., Kalil, C., Almeida, A., Kaiser, S., Cury, C., Jorge, J., Pereira, L., Jaeger, C., Ninho, L., Guimaraes, A., Gomes, A., Gomes, M., Pereira, G., Gagliardi, R., Daitz, C., Finimundi, H., Araujo, E., Ferreira, L., Seroqui, M., Saporito, W. Faustino, Morgado, S., Dutra, O., Laimer, R., Duda, N., Pereira, V., De Patta, M., Barroso, D., Costantini, C., Silva, J., Chaves Junior, H., Fleck, N., Brondani, R., Cunha, S., Botelho, R., Sehnem, E., Precoma, D. Bertolim, Ferraz, R. Franchin, Alves da Costa, F. Augusto, Motta, C., Atie, J., Houbraken, D., de Melo, R. Ferreira, Lotufo, P. Andrade, Coutinho, E., Vincenzo de Paola, A. Amato, Denie, D., Wollaert, B., Beerts, C., Vrolix, M., Mestdagh, I., Vervoort, G., van Welden, J., Vanwelden, J., Derycker, K., Vandekerckhove, Y., Jacobs, C., Stockman, D., Huyberechts, D., Scavee, C., Clinckemaille, N., Parque, J., Raepers, M., Mairesse, G., Malmendier, D., Herzet, J., Meeusen, K., Heidbuchel, H., Tincani, G., Desfontaines, P., De Bruyne, L., De Tollenaere, M., de Koning, K., De Bleecker, J., Banaeian, F., Capiau, L., O'Shea, V., Szto, G., Perrett, L., Purnell, P., Batta, C., Paul, V., Li, J., McKeirnan, M., Morrison, H., Lehman, R., Jones, S., Gates, P., Flecknoe-Brown, S., Silver, G., Davis, S., Kay, S., Dart, A., Slattery, A., Crimmins, D., Price-Smith, S., Colquhoun, D., Hoffmann, B., Arstall, M., Paraskevaidis, T., Hatheway, R., Anderson, C., Morell, Y., Vico, M., Teves, M., Sosa Liprandi, M., Morara, P., Severino, P., Buzzetti, C., Schygiel, P., Goloboulicz, A., Schmidberg, J., Xie, X. D., David, D., Formoso, I., Saravia Toledo, S., Codutti, O., Sanjurjo, M., Bowen, L., Sanchez, A., Alvarez, M., Rodriguez, M., Navarrete, S., Ramos, H., Meyer-Pannwitt, U., Venturini, C., Prado, A., Fernandez, E., Pozzer, D., Casares, E., Seibert, H., Povedano, G., Tommasi, A., Piskorz, D., Verdini, E., Nul, D., Gandur, H., Muntaner, J., Funes, I., Marino, J., Calderon, M., Manuale, O., Carne, M., Mackinnon, I., Raimondi, G., Lotti, J., Shatsky, K., Lorente, C., Vignau, S., Llanos, J., Nigro, A., Litvak, B., Iglesias, M., Liniado, G., Belcuore, M., Lanternier, G., Monaco, F., Kevorkian, R., Jure, D., Jure, H., Bianchini, M., Hominal, M., von Wulffen, M., Goicoechea, R., Huerta, M., Giannaula, R., Eden, M., Giacomi, G., Ceirano, C., Garrido, M., Perlo, D., Garcia Duran, R., Meiller, F., Gant Lopez, J., Zanotti, A., Fuselli, J., Arrieta, M., Femenia, F., Iriarte, M., Falu, E., Facello, M., Facello, A., Davolos, M., Estol, C., Moreno, V., Dran, R., Cendali, G., D'Amico, A., Bocanera, M., Cuneo, C., Rosell, M., Cuello, J., Morandini, M., Colombo, H., Saa Zarandon, R., Caruso, O., Novas, V., Cartasegna, L., Fracaro, V., Caccavo, A., Saravia, M., Bustamante Labarta, G., Valle, M., Budassi, N., Berli, M., Petrucci, J., Beloscar, J., Caceres, M., Amuchastegui, M., Ameriso, P., Ameriso, S., Garcia, M., Alvarez, C., Reguero, M., Allall, O., Rosales, E., Albisu, J., Ahuad Guerrero, R., Gonzalez, C., Vogelmann, O., Braunwald, Eugene, Antman, Elliott M., Mercuri, Michele F., Lanz, Hans, Murphy, Sabina A., Crompton, Andrea E., Oto, Ali, Degtyareva, E., Hellmers, J., Schreckenberg, A., Schmidt, M., Schmidt, A., Schiewe, C., Dreykluft, K., Finsterbusch, T., Schenkenberger, I., Frommhold, R., Schellong, S., Szymanowski, N., Schaefer, A., Kuehlenborg, A., Rinke, A., Yin, Y. H., Pilipenko, H., Rack, K., Kuhlmann, M., Proskynitopoulos, N., Pohl, W., Lewinsky, D., Piechatzek, R., Ayasse, D., Daut, W., Kara, M., Contzen, C., Weihrauch, D., Buhr, M., Ladenburger, K., Braun, R., Schnelzer, P., Bouzo, M., Sehr, B., Beyer-Westendorf, J., Vierbeck, S., Berrouschot, J., Dichristin, U., Bernhardt, P., Wurow, A., Al-Zoebi, A., Duprat, C., Roudaut, R., Leparree, S., Poulard, J., Corbut, S., Kacet, S., Deruche, E., Hermida, J., Arfaoui, M., Dinanian, S., El Jarroudi, M., Decoulx, E., Berger, N., Coisne, D., Dias, P., Blanc, J., Berbari, H., Belhassane, A., Boyer, M., Babuty, D., Boursin, P., Amarenco, P., El Jarroudi, F., Agraou, B., Li, T. F., Le Heuzey, J., Nappila, H., Virtanen, V., Salminen, O., Rasi, H., Sankari, T., Nyman, K., Viitaniemi, J., Maenpaa, A., Laheaar, M., Lucijanic, T., Lappalainen, T., Jakala, P., Valpas, S., Hussi, E., Kaarleenkaski, S., Huikuri, H., Ratnik, E., Vahula, V., Rajasalu, R., Rosenthal, A., Voitk, J., Paumets, M., Rivis, L., Laane, E., Kolk, R., Stern, A., Kaik, J., Serup-Hansen, K., Wiggers, H., Jakobsen, U., Torp-Pedersen, C., Giesbrecht, L., Bagatin, J., Svenningsen, A., Carevic, V., Jiang, X. J., Sand, N., Raae, D., Raymond, I., Petrovic, V., Overgaard, K., Olsen, R., Nielsen, H., Veng-Olsen, T., Talajic, M., Iversen, H., Madsen, H., Ibsen, H., Loof, A., Hassager, C., Christensen, L., Christensen, H., Dodt, K., Zidkova, E., Samkova, D., Vodnansky, P., Labrova, R., Spinar, J., Spacek, R., Slaby, J., Reichert, P., Jirsova, E., Podrazil, P., Pisova, J., Havlova, I., Petrova, I., Peterka, K., Olsr, J., Nechanicky, R., Melichar, M., Krocova, E., Machova, V., Ludka, O., Kvasnicka, J., Kuchar, R., Kovar, P., Kosek, Z., Kostkova, G., Kochrt, M., Kobza, R., Jirmar, R., Jerabek, O., Jelinek, Z., Jarkovsky, P., Jandik, J., Hubac, J., Honkova, M., Gregor, P., Campisto, Y., Morissette, A., Sussman, J., Gao, M., Frahm, E., Golan, L., Mitrovic, V., Zheng, Y., Zapata Staub, J., Zheng, X., Francek, L., Florian, J., Ferkl, R., Elbl, L., Cermak, O., Burianova, H., Brtko, M., Kailey, P., Retamal Matus, L., Fonseca, J., Han, R. J., Velthuysen, G., Bugueno, C., Orozco Linares, L., Bobbie, C., Heath, J., Lopez Giraldo, D., Raddatz, K., Zhao, X. L., Voehringer, Voehringer, Scott, L., Ho, K., Ho, V., Chen, X. P., Car, S., Hoag, G., Bolton, R., O'Mahony, W., Banville, P., O'Hara, G., Nicholson, R., Lamoureux, U., Kunkelova, V., Najarali, A., Mucha, M., Roth, M., Morrison, D., Morely, A., Mawji, A., Studenikow, E., Maranda, C., Vaillancourt, T., Zhang, X., Dong, Y. G., Standring, R., Feng, C., Fu, G. S., Wang, J. Q., Beeton, I., Dunn, S., Blagden, M., Price, R., Camm, J., Dougal, K., Mondaca Mondaca, P., Chapman, O., Davies, D., Choy, A., Duff, J., Zheng, Z. Q., Wilmott, R., D'Costa, D., Douglas, H., Lie, F., Ramasamy, V., Lindsay, S., Atkinson, C., Moncada Corredor, M., Linker, N., Finlayson, M., Lip, G., Brown, R., MacCallum, P., Ebano, P., MacLeod, M., McGhee, C., Marazzi, P., Maxwell, T., Isted, C., More, R., Helliwell, L., Murdoch, D., Andrews, A., Newby, D., Flint, L., Pye, M., Wright, L., Avery, D., Senior, R., Young, G., Sopher, M., Kennard, S., Storey, R., Zhang, P., Bridge, C., Hong, K., Turner, W., Walker, M., Venkataraman, A., Gilchrist, M., Watkin, R., Chung, A., Wright, A., Wright, J., Cobos, J., Mueller-Glamann, M., Yang, Y. J., Jeric, M., Li, A. Y., Yang, K., Liang, Y. Z., Xu, Y. M., Gu, J. Y., Berka, L., Xu, J. H., You, Z. G., Li, Y. E., Syan, G., Hoefer, K., Rivera Rodriguez, E., Brodova, P., Ludwig, I., Obreque, C., Manzur, F., Builes, A., Hoffmann, U., Jaramillo Munoz, C., Dorn, S., Veltkamp, R., Hoffmann, S., Li, B. G., Potthoff, S., Bar, M., Vogt, S., Delgado, P., Zhou, S. X., Schuppe, M., Bergovec, M., Muegge, A., Teitelbaum, J., Barbera, S., Horacek, T., Torres Carrasco, G., Vrazic, H., Zhang, Y. L., Ciglenecki, N., Liao, D. N., Pincetti, C., Fink, P., Teitelbaum, I., Carmona Perez, M., Junggeburth, J., Liu, Y., Schmid, S., Li, Z. Q., Jungmair, W., Spitzer, S., Opazo, M., Lu, Z. H., Tusek, S., Ferri Certic, J., Romic, I., Francetic, I., Makar Ausperger, K., Jelic, V., Jaksic Jurinjak, S., Knezevic, A., Lichtenstein, T., Lam, H., Bakliza, Z., Sutalo, K., Lam, S., Romero Llamas, R., Ma, S. M., Huynh, T., St-Germain, L., Luton, R., Accini, J., Lainesse, A., Perkins, L., Douglas, S., Dewar, C., Ma, P., Kouz, S., Kirner, D., Steiner, R., Matthews, J., MacCallum, C., Cvitkusic Lukenda, K., Schoen, B., Kleinecke-Pohl, U., Meusel, P., Koenig, H., Bauch, F., Lohrbaecher-Kozak, I., Grosse, B., Lueders, S., Venneklaas, U., Luttermann, M., Wulf, M., Maus, O., Seib, M., Malette, P., Roberts, P., Yang, Z. Y., Roy, M., Labonte, R., Kong, Y. Q., Samardzic, P., Qu, Z., Hong, L., Buksa, B., Qiu, Y., Tremblay, M., Talbot, P., Accini, M., Hernandez, H., Wang, D. M., Qi, S. Y., Corbalan, R., Wang, G. P., Cano, N., Aldana Diaz, I., Shi, X. J., Martinez, D., Wu, S. L., Fernandez Ruiz, R., Manriquez Silva, L., Manriquez, L., Rebolledo, C., Wei, M., Leon Pineda, L., Arroyave, C., Lopetegui, M., Arratia Diaz, P., Huang, D., Florenzano, F., Parada, A., Bonin, K., Delgado Restrepo, J., Stoehring, R., Taggeselle, J., Zarpentin, C., Huikuri, Heikke, Puripun, E., Yarows, S., Giugliano, Robert P., Scirica, Benjamin M., Wood, K., Sheehan, T., Yasin, M., Worley, S., Ruff, Christian T., Link, Mark S., Pointer, S., Capasso-Gulve, E., Yi, J., Dongas, B., and Yalcin, R.
- Subjects
Male ,medicine.medical_specialty ,medicine.drug_mechanism_of_action ,Pyridines ,medicine.medical_treatment ,Factor Xa Inhibitor ,Hemorrhage ,030204 cardiovascular system & hematology ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Edoxaban ,Risk Factors ,Physiology (medical) ,Internal medicine ,Thromboembolism ,Atrial Fibrillation ,Medicine ,Humans ,atrial fibrillation ,cardiovascular diseases ,030212 general & internal medicine ,Myocardial infarction ,Stroke ,Aged ,business.industry ,Warfarin ,Anticoagulants ,Atrial fibrillation ,Thrombolysis ,thromboembolism ,bleeding ,medicine.disease ,mortality ,stroke ,Thiazoles ,Treatment Outcome ,chemistry ,Anesthesia ,Cardiology ,Female ,Cardiology and Cardiovascular Medicine ,business ,TIMI ,medicine.drug ,Factor Xa Inhibitors - Abstract
Background— Whether the pattern of atrial fibrillation (AF) modifies the risk/benefit of anticoagulation is controversial. In ENGAGE AF-TIMI 48 trial (Effective Anticoagulation with Factor Xa Next Generation in Atrial Fibrillation–Thrombolysis in Myocardial Infarction 48), the factor Xa inhibitor edoxaban was noninferior to warfarin in preventing stroke or systemic embolic events and significantly reduced bleeding and cardiovascular mortality. However, detailed analyses by AF pattern have not been reported. Methods and Results— The 21 105 patients were categorized as having paroxysmal (P -adj =0.015) and permanent AF (1.95%/year; P -adj =0.004). Overall, all-cause mortality also was lower with paroxysmal (3.0%/year) compared with persistent (4.4%/year; P -adj P -adj Conclusions— In ENGAGE AF-TIMI 48 trial, patients with paroxysmal AF suffered fewer thromboembolic events and deaths compared with those with persistent and permanent AF. The efficacy and safety profile of edoxaban as compared with warfarin was consistent across the 3 patterns of AF. Clinical Trial Registration— URL: http://www.clinicaltrials.gov . Unique identifier: NCT00781391.
- Published
- 2016
35. Cerebrovascular events in 21 105 patients with atrial fibrillation randomized to edoxaban versus warfarin: Effective Anticoagulation with Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in Myocardial Infarction 48
- Author
-
Dougal, K., Venkataraman, A., Murdoch, D., Blagden, M., Dunn, S., MacCallum, P., Young, G., Lip, G., Senior, R., Brown, R., Sopher, M., Ebano, P., Linker, N., Atkinson, C., Lindsay, S., MacLeod, M., More, R., Ramasamy, V., Chapman, O., Lie, F., Beeton, I., McGhee, C., Wilmott, R., Dickinson, D., Douglas, H., Davies, D., D'Costa, D., Finlayson, M., Wright, A., Avery, D., Wright, L., Pye, M., Marazzi, P., Flint, L., Newby, D., Kennard, S., Andrews, A., Storey, R., Helliwell, L., Bridge, C., Choy, A., Turner, W., Walker, M., Wright, J., Smith, S., Jones, D., Maxwell, T., Chung, A., Isted, C., Cohen, A., Camm, J., Price, R., Watkin, R., Gilchrist, M., Duff, J., Aggarwal, R., Eldred, R., Adler, P., Chehayeb, R., Vandekerckhove, Y., Gordon, L., Jones, S., Young, C., Coyle, G. Stagi, Ferguson, D., Lang, J., Simmons, T., Langevin, E., Faucett, S., Ledbetter, L., Royse, H., Lentz, M., Smith, D., Lesser, M., Hartley, L., Lewis, D., Bonds, C., Lillestol, M., Miller, D., Ling, L., Murphy, R., Littlefield, R., Wofford, E., Lomnitz, D., Shah, D., Lone, B., Davids, M., Looby, R., Ault, S., Lui, H., Wright, H., Lurie, M., Edelstein, J., Macomber, J., Bush, D., Magee, A., Doctor, A., Mainigi, S., Lisiecki, B., Makam, S., Casas, R., Mandviwala, M., Hernandez, S., Marar, I., Rabadi-Marar, D., Marenberg, M., Bedenko, E., Massin, E., Hicks, T., McCartney, M., Stubbs, L., McGarvey, J., Schwarz, L., McGuire, K., Miranda, J., McKenzie, M., Rodkey, K., McKnight, T., Paul, J., McLaurin, B., Lack, A., Mega, J., Marti, J., Meholick, A., Skinner, J., Mehrle, A., Wall, J., Mendelson, R., Cervellione, K., Mercado, A., Cajulis, C., Michlin, B., Romero-Colon, J., Milas, J., Sanders, D., Miller, R., Sanchez, S., Miller, S., Gryczan, J., Mody, F., Strugatsky, S., Moran, J., Garner, S., Morledge, J., Bowman, B., Mouhaffel, A., Parrott, N., Mounsey, P., Schuler, C., Mowdy, M., Todd, S., Mullen, P., Raziano, S., Murphy, A., Oehmann, V., Nadar, V., Parker, A., Naidu, J., West, M., Nallasivan, M., Goza, J., Nguyen, T., Nomanee, S., Nielsen, R., Wilmot, M., Oberoi, M., Thakkar, N., Oppenheimer, K., McCormick, J., Orchard, R., Garcia, L., Osborne, J., Gonzalez, M., Oza, S., Joseph, L., Patnam, S., Dennison, K., Pavon, H., Gorry, N., Pearlstein, R., Montayne, S., Pentz, W., Duncan, D., Peters, P., Chacon, L., Petruzziello, F., Morlando, F., Pettis, K., Brown, F., Pezzella, S., Kirk, D., Poulathas, A., Cush, S., Pratt, R., Neeper, L., Pribble, A., Lowe, K., Pudi, K., Sham, L., Pugeda, J., Ebert, J., Quadrel, M., Rafla, E., Quinlan, E., Reed, C., Quinn, J., Hemmen, C., Rama, P., Domingo, D., Redondo, V., Wroblewski, J., Renzi, M., Stanley, E., Richwine, R., Pazier, P., Roberts, J., Riofrio, K., Braun, D., Robinson, J., Cherrico, M., Roehll, W., Hollihan, P., Rosado, J., Barnhorst, M., Rosen, R., Martin, C., Ross, S., Freeman, R., Ruoff, G., Nelson, T., Sacco, J., Ball, E., Samal, A., Schomburg, J., Sandberg, J., Lafave, J., Savin, V., Clifton, R., Schaefer, S., Fekete, A., Schneider, R., Schneider, W., Schulman, D., Mercer, S., Seals, A., Ullig, T., Holt, A., Seide, H., Mather, N., Shah, G., Witt, P., Shalaby, A., Seese, M., Shanes, J., Fleets, J., Shaoulian, E., Hren, A., Sheikh, K., Hengerer, T., Shih, H., Browning, J., Shoukfeh, M., Stephenson, L., Siler, T., Champagne, M., Simpson, P., Meyer, R., Singh, N., Turner, K., Singh, V., Nelson, M., Skierka, R., Hughes, B., Keene, R., Smith, R., Hodnett, P., Spangenthal, S., Thomason, L., Sperling, M., Vasquez, E., Spivack, E., McCartney, P., Staniloae, C., Liu, M., Steljes, A., Cox, C., Struble, R., Vittitow, T., Suresh, D., Frost, J., Swerchowsky, V., Freemyer, D., Szulawski, I., Herwehe, S., Tahirkheli, N., Springer, K., Takata, T., Bruton, T., Talano, J., Leo, L., Tami, L., Corchado, D., Tatarko, M., Swauger, M., Tawney, K., Dastoli, K., Teague, S., Young, K., Tee, H., Mitchell, T., Teixeira, J., Southam, D., Torres, M., Romero, N., Tucker, P., Salas, L., Updegrove, J., Hanna, K., Val-Mejias, J., Harrelson, K. Gonzalez, Vemireddy, D., Cardoza, T., Verma, S., Parsons, T., Vicari, R., Warren, K., Vijay, N., Washam, M., Vossler, M., Kilcup, S., Walsh, R., Renaud, K., Ward, S., Locklear, T., Waxman, F., Sanchez, G., Weiss, R., St Laurent, B., Westcott, J., Truva, C., Williams, D., Gibson, C., Williams, R., Dowling, C., Willis, J., VonGerichten, S., Wood, K., Capasso-Gulve, E., Worley, S., Pointer, S., Yarows, S., Sheehan, T., Yasin, M., Preston, S., Yi, J., Dongas, B., Yousuf, K., Fisher, M., Zakhary, B., Curtis, S., Zeig, S., Mason, T., Zellner, C., Harden, M., Roper, E., Waseem, M., Grammer, M., Ruff, Christian T., Giugliano, Robert P., Beerts, C., Vrolix, M., Mestdagh, I., Vervoort, G., van Welden, J., Vanwelden, J., Derycker, K., Jacobs, C., Stockman, D., Huyberechts, D., Scavee, C., Clinckemaille, N., Parque, J., Raepers, M., Mairesse, G., Malmendier, D., Herzet, J., Meeusen, K., Heidbuchel, H., Tincani, G., Desfontaines, P., De Bruyne, L., De Tollenaere, M., de Koning, K., De Bleecker, J., Banaeian, F., Capiau, L., O'Shea, V., Szto, G., Perrett, L., Purnell, P., Batta, C., Paul, V., Li, J., McKeirnan, M., George, F., Valentine, H., Gerber, J., Hinchion, N., Morrison, H., Lehman, R., Gates, P., Flecknoe-Brown, S., Silver, G., Davis, S., Kay, S., Dart, A., Slattery, A., Crimmins, D., Price-Smith, S., Colquhoun, D., Hoffmann, B., Arstall, M., Paraskevaidis, T., Anderson, C., Morell, Y., Vico, M., Teves, M., Sosa Liprandi, M., Morara, P., Severino, P., Buzzetti, C., Schygiel, P., Goloboulicz, A., Schmidberg, J., Formoso, I., Saravia Toledo, S., Codutti, O., Sanjurjo, M., Gillespie, E., Keane-Richmond, P., Gogia, H., Ewing, B., Goldscher, D., Latteri, J., Goldstein, M., Bowen, L., Sanchez, A., Alvarez, M., Rodriguez, M., Navarrete, S., Ramos, H., Venturini, C., Prado, A., Fernandez, E., Pozzer, D., Casares, E., Povedano, G., Tommasi, A., Piskorz, D., Verdini, E., Nul, D., Gandur, H., Muntaner, J., Funes, I., Marino, J., Calderon, M., Manuale, O., Carne, M., Mackinnon, I., Raimondi, G., Lotti, J., Shatsky, K., Lorente, C., Vignau, S., Llanos, J., Nigro, A., Litvak, B., Iglesias, M., Liniado, G., Belcuore, M., Lanternier, G., Monaco, F., Kevorkian, R., Jure, D., Jure, H., Bianchini, M., Hominal, M., von Wulffen, M., Goicoechea, R., Huerta, M., Giannaula, R., Eden, M., Giacomi, G., Ceirano, C., Garrido, M., Perlo, D., Garcia Duran, R., Meiller, F., Gant Lopez, J., Zanotti, A., Fuselli, J., Arrieta, M., Femenia, F., Iriarte, M., Falu, E., Facello, M., Facello, A., Davolos, M., Estol, C., Moreno, V., Dran, R., Cendali, G., D'Amico, A., Bocanera, M., Cuneo, C., Rosell, M., Cuello, J., Morandini, M., Colombo, H., Saa Zarandon, R., Caruso, O., Novas, V., Cartasegna, L., Fracaro, V., Caccavo, A., Saravia, M., Bustamante Labarta, G., Valle, M., Budassi, N., Berli, M., Petrucci, J., Beloscar, J., Caceres, M., Amuchastegui, M., Ameriso, P., Ameriso, S., Garcia, M., Alvarez, C., Reguero, M., Allall, O., Rosales, E., Albisu, J., Ahuad Guerrero, R., Gonzalez, C., Vogelmann, O., Braunwald, Eugene, Antman, Elliott M., Mercuri, Michele, Shi, Minggao, Dave, Jay, Duggal, Anil, Betcher, Joshua M., Grip, Laura T., Murphy, Sabina A., Deenadayalu, Naveen, Lowe, Cheryl, Wiviott, Stephen D., Silverman, Scott, Gowda, S., Rafala, E., Graham, S., Bonora, M., Griffin, S., Aull, L., Griffin, J., Goodman, V., Grossman, C., Davis, A., Grove, D., Mabe, K., Guarino, J., Gabela, W., Guarnieri, T., Guerrero, Guerrero, Foster, B., Guthrie, R., Felsman, D., Gvora, T., McLean, R., Rost, Natalia S., Hack, T., Morelli, L., Hamroff, G., Bentivenga, L., Han, M., Cavanna, L., Harris, J., Bobade, M., Hearne, S., Krater, C., Heiman, M., Dandekar, U., Henderson, D., Millard, D., Henry, S., Harkins, V., Hermany, P., Batchell, K., Herrod, J., Miranda, D., Herson, S., Carey, G., Hinchman, D., Vieira, P., Hippert, R., Dutter, S., Hoekstra, J., Homan, J., Homayouni, A., Horton, K., Sloss, D., Hotchkiss, D., Turner, N., Houchin, V., Adams, K., Howard, V., Hays, D., Howard, L., Craft, D., Huang, P., Hunter, J., Battistelli, E., Hurst, P., Garza, M., Hussain, M., Tambawala, M., Ison, R., Butcher, S., Jardula, M., Andresen, T., Johnson, F., Phillips, T., Jones, R., Hughett, G., Jovin, I., Nichols, M., Judson, P., Royes, A., Kahn, B., Coombs, V., Kai, W., Dugal, J., Kandath, D., Kostedt, G., Kaplan, K., Cook, S., Kapoor, A., Ruggiero, M., Karunaratne, H., Behm, K., Kastelic, R., Davis, C., Keller, R., Keller, J., Kerkering, M., Bartholomaus, D., Kersh, R., Buhler, A., Kesselbrenner, M., DiCorcia, L., Khan, B., Binns, M., Khan, M., Khan, G., Kindman, L., Averett, P., Korpas, D., Godfrey, C., Kotha, P., Sanchez, E., Kozlowski, J., Watts, S., Krichmar, P., Marquez, D., Laliotis, A., Jauregui, V., Lambert, C., Landau, C., Davuluri, A., Dave, B., Dave, K., Wulf, A., Datta, S., Leka, G., Daniels, S., Morgan, T., Dang, N., Sarpola, N., Curtis, B., Nelson, L., Cowan, L., Masson, E., Cottiero, R., Mullinax, K., Cossu, S., Svadbik, L., Corbett, B., Martinez, E., Concha, M., Cole, J., Salpas, S., Colan, D., Bossaers, J., Cohen, R., Dutka, C., McClelland, M., Clay, A., Clapp, T., Bagby, J., Ciaramita, J., Sawaya, K., Chaturvedi, S., Tamayo, M., Charlat, M., Hatfield, G., Chang, M., Phan, D., Carr, K., Jameson, L., Ebreo, N., De Lemos, J., Debes, C., Dean, J., Warmack, D., DeGarmo, R., Caplan, J., Hartranft, E., Canosa, R., Canaday, D., Morton, S., Cader, C., Al-Maliky, T., Bybee, K., Triano, A., Brown, H., Frey, W., Brilakis, E., Terry, P., Bradley, A., Ziegler, K., Bowden, W., Wade, W., Bouchard, A., Hickenbotham, D., Borsheim, M., Vernon, M., Blue, B., Bloomberg, K., Bloomberg, R., Ensminger, E., Blonder, R., Talbot-Lawson, C., Block, T., Antonino, M., Bingham, S., Langone, L., Bilazarian, S., Bilal, B., Bernard, J., Ibarra, M., Berk, M., Garman, V., Bensimhon, D., Swaim, D., Beinart, S., Craig, M., Bedwell, N., Carey, J., Luis-Valdes, M., Bedoya, R., Hoffman, T., Beasley, R., Benton, J., Bartkowiak, A., Barrington, P., Faircloth, C., Barker, T., Altonen, D., Barber, M., Campbell, G., Baman, R., Batista, M., Baine, S., Thompson, B., Ayesu, K., Baldwin, E., Awasty, V., Cobos, D., Aude, Y., Strickland, S., Attanti, S., Rasmussen, L., Arouni, A., Shoaf, R., Arnold, T., York, T., Anderson, J., Persechino, F., Amin, M., Khetarpal, S., Amin, K., Lane, B., Alsheikh, T., MacDonald, H., Almquist, A., Biscardi, R., Allison, J., Godsey, W., Aliyar, P., Genova-Peeva, E., Desai, A., Alexander, J., Brubaker, S., Akhter, F., Lim, G., Ahmadpour, H., Hussain, A., Ahmad, A., Beck, P., Reiling, S., Barash, B., Adler, J., Lohman, J., Panella, M., Abi-Mansour, P., Mackin, A., Moriarty, A., Green, M., Shandra, T., Zhurba, S., Logvinov, Y., Zharinov, O., Mudruk, I., Yena, L., Nahrebetskyy, V., Yagensky, A., Serik, S., Volkov, V., Goncharov, O., Vizir, V., Sklyanna, O., Vatutin, M., Drapchak, I., Vakaliuk, I., Steward, A., Desire, A., Waters, L., Tykhonova, S., Kuznetsov, I., Tseluyko, V., Lyzohub, S., Sychov, O., Perebetiuk, L., Stanislavchuk, M., Sirenko, Y., Zamlynskyy, M., Shvetz, N., Goncharova, I., Shcherbak, V., Ishchuk, V., Shatilo, V., Rudyk, I., Chendey, T., Rishko, M., Gamachek, O., Rebrov, B., Devenport, S., Leonidova, V., Prokhorov, O., Nekrasa, A., Potapenko, P., Dovgan, N., Parkhomenko, A., Ushakova-Sokolova, L., Briscoe, C., Dhar, S., Ucik, S., DiGiovanna, M., Ostrovska, L., Fedotov, S., Malynovsky, Y., Gorna, O., Lizogub, V., Kyyak, Y., Kupnovytska, I., Stets, R., Kraydashenko, O., Usan, N., Kraiz, I., Kaplan, P., Koval', O., Ohirko, O., Koval, V., Dvoieglazova, M., Kotseruba, V., Petyunina, O., Kopytsya, M., Vasylets, V., Kolomyyits, S., Gerasimenko, N., Kaydashev, I., Blihar, O., Karpenko, Y., Nevolina, I., Karpenko, O., Samburg, Y., Godlevska, O., Husyev, V., Horbach, L., Dzublik, Y., Gavrysyuk, V., Sorokivskyy, M., Faynyk, A., Vasilyeva, L., Dzyak, G., Kulynych, R., Dotsenko, S., Lebedynskaya, M., Bereznyakov, I., Tisdale, L., Donovan, D., Rodriguez, L., Vlasyuk, Z., Bazylevych, A., Azhdari, M., Batushkin, V., Zoghi, M., Yigit, Z., Yigit, F., Yalcin, R., Tandogan, I., Turgut, O., Oto, A., Kanadasi, M., Kabul, K., Ermis, C., Erdogan, D., Ceyhan, C., Cayli, M., Calik, A., Cakmak, N., Bayata, S., Ata, N., Demir, H., Akilli, H., Acikel, M., Puripun, E., Vorasettakarnkij, Y., Mekara, W., Sukonthasarn, A., Panpunuan, P., Sritara, P., Sripracha, A., Piyayotai, D., Bamrungpong, P., Laothavorn, P., Sriprasert, S., Kiatchoosakun, S., Sinthusopa, W., Kaewsuwanna, P., Pornchaiyasit, K., Jirasirirojanakorn, K., Kuo, J. Y., Yeh, H. I., Tsai, W. C., Wang, J. H., Lee, S. C., Ueng, K. C., Pan, Y. F., Tseng, W. K., Chiu, C. Z., Shyu, K. G., Lin, K. H., Pai, P. Y., Lee, J. T., Lin, T. H., Lai, W. T., Wang, C. L., Kuo, C. T., Chen, Y. F., Huang, J. L., Chen, Y. P., Hsia, C. H., Yeh, T. C., Chiou, C. W., Wu, Y. W., Chiang, F. T., Yu, W. C., Chiang, C. E., Wu, W. S., Cheng, C. C., Dotani, I., Slater, I. Petrova, Moccetti, T., Broberg, M., Thulin, J., Gunnarsson, A., Stenberg, A., Sundholm, C., Ronn, F., Johansson, M., Rautio, A., Moodh, J., Randers, F., Eriksson, G., Malmqvist, L., Edlund, M., Kozak, P., Hakansson, E., Koskinen, P., Jernhed, H., Juul-Moller, S., Winberg, L., Herlitz, J., Karlsson, L., Engdahl, J., Ostberg, S., Dettmann, S., Bengtsson, A. Stener, Carlsson, T., Persson, L., Blomstrom, P., Andersson, R., Blom, K. Berndtsson, Akerberg, A., Appelros, P., Astier, L., Villuendas, R., Dachs Delgado, M., Terns, M., Fernandez Alvarez, R., Fernandez, M., Arias, J., Diaz-Pintado, M., Merino, J., Blanco Abril, S., Manzano, L., Barquero, R., Lopez Garcia-Aranda, V., Delgado, A., Hernandez Madrid, A., Moure, M., Gonzalez Juanatey, J., Perez Guevara, M., Diez Tejedor, E., Asensio, A., De Arce Borda, A., Calvo, G., Calvo, C., Cabero, P., Bruguera Cortada, J., Puertas, I., Blanco Coronado, J., Manzanal Rey, A., Arcocha Torres, M., Kim, J. Y., Rim, S. J., Na, J. O., Rha, S. W., Kwak, J. J., Namgung, J., Shin, D. G., Lee, S. H., Joung, B. Y., Lee, M. H., Chun, M. Y., Kim, Y. J., Seo, J. B., Kim, S. H., Park, S. J., Kim, J. S., Park, J. H., Kim, J. H., Park, M. S., Kim, J. T., Cha, M. J., Kim, H. S., Seo, J. S., Kim, D. S., Jin, E. S., Kim, C. J., Choi, K. J., Kang, D. H., Lee, J. M., Jeon, H. K., Jung, J. W., Hyon, M. S., Lee, H. W., Hong, T. J., Lee, K. H., Han, S. H., Oh, Y. S., Chung, W. S., Hong, K. S., Choi, H. H., Ryu, D. R., Cho, B. R., Kim, D. H., Cha, J. K., Han, M. G., Bae, H. J., Wessels, L., Venter, T., Le Roux, M., Van Zyl, L., Goosen, Y., Van Der Merwe, N., Johnston, H., Soma, P., Munnik, M., Snyders, F., Duki, Y., Naidoo, D., Taljaard, J., Mitha, I., Kelfkens, Y., Wilson, L., Gani, M., Nunkoo, T., Essop, M., Mostert, M., Engelbrecht, J., Botha, L., Ellis, G., Allman, J., Dalby, A., Poynton, M., Basson, M., Erasmus, L., Badenhorst, J., Bollova, D., Zareczky, P., Kokles, M., Zachar, A., Kmec, J., Slanina, M., Morsky, J., Ruffini, L., Fedacko, J., Pella, D., Mazur, J., Reptova, A., Kasperova, V., Hofmanova, J., Hranai, M., Hatala, R., Hatalova, K., Dzupinova, M., Dzupina, A., Vankova, L., Duris, T., Dulka, T., Dulkova, K., Kosmalova, V., Dukat, A., Banikova, A., Ambrovic, I., Ambrovicova, V., Tesic, M., Golshmid, M., Ruda, M., Topolnitchi, O., Castro, C., Ostojic, M., Tesic, B. Vujisic, Mitrovic, P., Vasiljevic-Pokrajcic, Z., Davicevic, Z., Tavciovski, D., Milinkovic, I., Olson, A., Drozdiak, R., Seferovic, P., Kalezic, T., Putnikovic, B., Polovina, M., Potpara, T., Tasic, N., Otasevic, P., Djokic, I., Miloradovic, V., Djokovic, A., Krotin, M., Ilic, B., Ilic, S., Erceg, P., Despotovic, N., Bjelobrk, M., Adjic, N. Cemerlic, Majstorovic, A., Celic, V., Djordjevic-Radojkovic, D., Apostolovic, S., Motylev, I., Zubeeva, G., Kononenko, O., Zenin, S., Mankhaeva, B., Zateyshchikova, A., Zotova, I., Zateyshchikov, D., Nikulina, N., Yakushin, S., Petrochenko, A., Yakusevich, V., Rodina, N., Volkov, D., Kirgizova, A., Vishnevsky, A., Rossovskaya, M., Ustyugov, S., Bulygin, S., Timofeev, A., Solovyev, A., Tikhonova, E., Kositsyna, I., Tereshenko, S., Isakov, L., Tarasov, N., Dronov, D., Suprun, E., Erofeeva, S., Sobolev, K., Lapidus, N., Sizova, Z., Orlov, V., Sinitsina, I., Vorontsova, S., Sidorenko, B., Agirov, M., Shogenov, Z., Lebedev, E., Shaposhnik, I., Repin, M., Karoli, N., Rebrov, A., Letaeva, M., Raskina, T., Pikalova, N., Poluyanova, N., Matveeva, I., Polkanova, E., Nilk, R., Panov, A., Laguta, P., Panchenko, E., Patrusheva, S., Novikova, N., Khromova, O., Nikolskaya, I., Nikolaev, A., Nikolaev, K., Lamden, D., Lukyanov, Y., Belousova, L., Lila, A., Moiseeva, Y., Libov, I., Maslova, A., Libis, R., Volkova, E., Levashov, S., Tereschenko, L., Lavrova, O., Rychkov, A., Kuznetsov, V., Kostenko, O., Kozyrev, O., Polyanskaya, E., Koziolova, N., Karabalieva, S., Kostenko, V., Khrustalev, A., Khrustalev, O., Tsareva, E., Khokhlov, R., Sinitsina, O., Khokhlov, A., Kireenkov, I., Khirmanov, V., Kosenko, B., Buza, V., Karpov, Y., Mazovets, O., Gratsiansky, N., Laptev, I., Goloshchekin, B., Kratskina, T., Golitsyn, S., Valovyeva, S., Glezer, M., Valuyshkih, E., Gilinskaya, O., Soin, I., Filatov, A., Kirichek, N., Esip, V., Egorova, L., Zyatenkova, E., Drapkina, O., Puchinyan, N., Dovgalevsky, P., Masin, A., Demko, A., Pokutneva, O., Chumakova, G., Khlevchuk, T., Bokarev, I., Yukhno, E., Berns, S., Kosolapov, Y., Belenky, D., Larina, V., Bart, B., Bashkireva, A., Barbarash, O., Alexandrova, L., Ballyuzek, M., Chernyavskaya, T., Arutyunov, G., Zhukova, N., Tudoran, C., Tudoran, M., Topolnitchi, L., Spinu, C., Stamate, S., Plosca, P., Sipciu, D., Ardelean, A., Popescu, M., Cozma, M., Pop, C., Serban, D., Minescu, B., Costache, L., Iosipescu, L., Jurca, S., Dragomir, D., Sirbu, I., Dobreanu, D., Voicu, O., Dobre, I., Jemna, D., Crisu, D., Anciu, M., Cristea, M., Parasteac, M., Creteanu, M., Constantinescu, M., Ghionea, M., Coman, I., Andor, M., Ciobotaru, G., Bolohan, F., Doka, B., Bobescu, E., Ochean, V., Bengus, C., Badila, E., Bartos, D., Matei, C., Apetrei, E., Ciortea, M., Albulescu, P., Soares, D., Santos, J., Veiga Pais Nunes, L., Santos, O., Goncalves, A., Salgado, A., Leitao Marques, A., Oliveira, D., Monteiro, P., Neves, E., Martins, D., Maymone, D., Madeira, J., Lopes, S., Gil, V., Correia, J., Matias, F., Nawrot, M., Zielinski, M., Krauze, R., Zarebinski, M., Kudlicki, J., Wysokinski, A., Muzalewski, P., Wrobel, W., Turbak, R., Malanska, A., Szolkiewicz, M., Spyra, J., Sendrowski, D., Norwa-Otto, B., Ruzyllo, W., Ronkowski, R., Rozmyslowicz-Szerminska, W., Rewinska, H., Zienciuk-Krajka, A., Raczak, G., Bojanowska, E., Polaszewska-Pulkownik, V., Pogorzelska, H., Janczewska, D., Podjacka, D., Olszewski, M., Nowak, J., Nej, A., Niezgoda, K., Nessler, B., Nessler, J., Biniek, D., Napora, P., Myslinski, W., Mosiewicz, J., Kosmalska, K., Miekus, P., Chmielowski, A., Mazur, S., Kosmaczewska, A., Wnetrzak-Michalska, R., Sznajder, R., Matyszczak-Toniak, L., Jaguszewska, G., Lysek, R., Szymanska, K., Lubinski, A., Stopyra-Poczatek, M., Lewczuk, J., Wierzykowski, T., Lesnik, J., Kus, W., Sklodowskiej-Curie, M., Muzyk-Osikowicz, M., Krzyzanowski, W., Borowski, W., Korzeniak, R., Benicka, E., Konieczny, M., Kaliszczak, R., Karczmarczyk, A., Tymendorf, K., Kania, G., Kaminski, L., Pacholska, A., Kaczmarek, B., Jurowiecki, J., Ciezak, P., Jazwinska-Tarnawska, E., Makowiecka-Ciesla, M., Januszewicz, A., Mroczkowski, P., Gniot, J., Zajac, E., Gieroba, A., Guziewicz, M., Domanska, E., Laskowska-Derlaga, E., Derlaga, B., Ptak, A., Dabrowska, M., Cymerman, K., Krzystolik, A., Busz-Papiez, B., Cieslak, B., Bronisz, M., Baszak, J., Korzeniowska-Adamus, J., Adamus, J., Nario, K., Villamor, L., Aquino, M., To, R., Gilo, L., Roxas, A., Joaquin, F., Rogelio, G., Enad, C., Matiga, G., Vallenas, M., Coching, R., Zapanta, M., Barcinas, R., Sambaz, C. M., Habibi, S., Babilonia, N., D'Souza, A., Delgado, S., Horna, M., Yanac Chavez, P., Fernandez Rodriguez, K., Torres, P., Rodriguez, A., Honores Armas, B., Negron Miguel, S., Bautista, C., Minchola, J., Rodriguez, J., Medina Palomino, F., Araoz Bedregal, S., Llerena, N., Carrion, A., Cullen, T., Eade, J., Lema, J., Luna, C., Chavez, C., Esteves Mendoza, R., Cabrera, J., Tejada Guillen, M., Bustamante, G., Enger, S., Dunn, K., Tveit, A., Thunhaug, H., Sandvik, J., Melbue, R., Hofsoy, K., Claussen, H., Atar, D., Kennett, K., Skelton, L., Troughton, R., Cammell, R., Scott, D., Turner, A., Hart, H., Tomlinson, J., Hamer, A., Green, B., Monkley, R., Fisher, R., Copley, M., Doughty, R., Borthwick, L., White, H., Benatar, J., Kjentjes, M., O'Meeghan, T., Anscombe, R., Hofmeyer, H., van der Heijden, D., Mevissen, H., Kooiman, E., Mannaerts, H., Muijs, L., Kietselaer, B., Daniels, R., Hazeleger, R., de Vos, R., Radder, I., de Groot, J., Buiks, C., Jones, A., Bruning, T., van Welsen, I., Alhakim, M., Moran Velazquez, E., Velasco Sanchez, R., Ortiz, A., Sanchez Diaz, C., Magallanes, G., Nevarez Ruiz, L., Avila, H., Mendez-Machado, G., Grajales, A., Llamas Esperon, G., de la Mora, S., Leiva-Pons, J., Jaramillo, A., Garcia-Castillo, A., Alcantara Colin, M., Garcia, N., Franco Valles, J., Casares Ramirez, M., Delgadillo, T., Carrillo, J., Cardona Munoz, E., Cedano Limon, M., Calvo Vargas, C., Hurtado, A., Bayram Llamas, E., Fujiwara, Y., Yoshioka, K., Nomura, H., Yoshino, H., Tanaka, K., Yonehara, T., Matsuda, K., Yamashita, T., Takiguchi, M., Yamashina, A., Ito, Y., Yamamoto, Y., Sasaki, S., Yamagishi, T., Yamano, R., Yamada, T., Sakamoto, Y., Yamabe, H., Kuroda, T., Yagi, H., Sato, A., Yagi, M., Sakai, Y., Usuda, K., Onishi, M., Ueyama, Y., Yasumoto, S., Uematsu, M., Terakura, K., Tsuboi, N., Yoshida, K., Tsuboi, H., Nishiya, Y., Tanouchi, J., Uchida, M., Watanabe, E., Takeuchi, S., Yamagishi, K., Takenaka, T., Yahata, A., Takeda, K., Sakurai, Y., Takahashi, T., Kishi, N., Takahashi, A., Takahashi, W., Mohri, S., Takagi, M., Asakura, H., Sumii, K., Miyazaki, E., Sugi, K., Ueda, J., Shoji, Y., Shigenari, M., Shirai, T., Narumi, M., Seino, Y., Fujimoto, E., Satoh, A., Oosawa, N., Sasaki, T., Ooki, H., Sakurai, S., Hayashi, N., Sakuragi, S., Nakano, A., Sakagami, S., Tanikawa, I., Ozaki, Y., Moriyama, H., Onaka, H., Narita, Y., Okumura, K., Kitani, S., Okishige, K., Wada, H., Okazaki, O., Nakashima, M., Okajima, K., Moriyama, Y., Okada, K., Tanabe, M., Oguro, H., Sugeno, M., Ogawa, T., Junko, H., Ochiai, J., Nagase, T., Nishi, Y., Oyama, H., Naito, S., Sakata, Y., Nagai, Y., Murata, J., Munemasa, M., Sakamoto, S., Miyauchi, Y., Kimizu, T., Miyamoto, N., Takeda, M., Mita, T., Satake, M., Meno, H., Ebina, E., Kaneno, Y., Masuyama, T., Koya, E., Kurabayashi, M., Yumoto, I., Koretsune, Y., Tamura, S., Kohno, M., Kikuchi, R., Kobayashi, Y., Igarashi, C., Kitazawa, H., Ichikawa, Y., Kazatani, Y., Ishida, A., Kato, K., Fujii, R., Kamiyama, K., Iida, S., Kamijo, M., Nakahara, F., Kamakura, S., Adachi, C., Kakinoki, S., Nagatome, H., Iwasaki, T., Sakuma, Y., Iwade, K., Ito, T., Itamoto, K., Ise, M., Ishimaru, S., Tomita, H., Ishii, Y., Nozaki, T., Ishibashi, Y., Nakamura, K., Inomata, T., Noguchi, H., Ino, H., Higuchi, K., Iijima, T., Miyamoto, C., Iesaka, Y., Kawaguchi, A., Hirayama, A., Nakagawa, Y., Higashikata, T., Oga, Y., Hiasa, Y., Shimazu, Y., Hashimoto, Y., Nakahara, Y., Haruna, T., Fuki, Y., Harada, K., Kumagai, S., Hara, S., Naganuma, M., Hagiwara, N., Kamitake, C., Furukawa, Y., Yamaguchi, A., Funazaki, T., Fujimoto, C., Fukuda, N., Harada, J., Fukamizu, S., Fujita, T., Ichishita, Y., Fujimoto, K., Omae, K., Fujimoto, S., Kotera, M., Fujii, E., Kozeni, S., Fujii, K., Fujiwara, M., Endo, H., Tsukimine, A., Arakawa, S., Mino, K., Anzai, T., Matsushita, C., Ajioka, M., Masaki, W., Akihisa, U., Hirahara, T., Furiozzi, F., Zaca, V., Gagliano, M., Toschi, V., Breschi, M., Severi, S., Cannoni, S., Rasura, M., Granzow, K., Raisaro, A., Fenu, L., Piseddu, G., Paradiso, G., Pirelli, S., Marciano, C., Filardi, P. Perrone, Lioy, E., Penco, M., Bulgari, M., Metra, M., Babbolin, M., Merlini, P., Francalacci, G., Marino, P., Raggi, F., Lo Pinto, G., Gaggioli, G., Laffi, Laffi, Murena, E., Grassia, V., Bosco, B., Fattore, L., Di Niro, M., Di Pasquale, G., Mazzone, C., Di Lenarda, A., Mariani, M., De Servi, S., De Pace, D., De Caterina, R., Forgione, C., Cuccia, C., Peruzzotti, L., Comi, G., Cervi, E., Boriani, G., Giovannelli, F., Berni, A., Platner, N., Zeltser, D., Kisos, D., Tsalihin, D., Belatsky, V., Swissa, M., Aloni, I., Shochat, M., Sterlin, J., Schiff, E., Logvinenko, S., Rozenman, Y., Givoni, H., Ouzan, E., Karny, M., Lishner, M., Ben Ari, M., Lewis, B., Eldadah, Z., Genin, I., Klainman, E., Majdoub, A., Hayek, T., Quick, R., Roshrosh, M., Hasin, Y., Dagan, T., Grossman, E., Rouwaida, S., Gottlieb, S., Goldhaber, M., Goldhaber, A., Ghantous, R., Francis, A., Ron, G. Avraham, Elias, M., Gilat, T., Lahav, M., Marcoviciu, D., Dicker, D., Lasri, E., Atar, S., Dharmarao, A., Zanwar, I., Thakur, B., Vinod, M. Vijan, Kaur, A., Varma, S., Thankaraj, L., Srinivas, A., Gupta, R., Singh, G., Sudheer, R., Shetty, G., Sethia, S., Sethia, A., Bansal, N., Sethi, K., Singh, R., Sawhney, J., Arora, T., Sarna, M., Jadhav, D., Sant, H., Gadepalli, R., Saha, D., Barai, A., Roy, D., Bekal, S., Reddy, R., Shankar, A. Ravi, Vuriya, A., Rao, M., Jambula, H., Premchand, R., Kharalkar, H., Pinto, B., Babbar, A., Patki, N., Jasani, B., Parekh, P., Sababathi, R., Pandurangi, U., Shams, S., Purayil, M. Padinhare, Angel, J., Gurusamy, P., Oomaan, A., Natarajan, S., Narendra, J., Shelke, S., Namjoshi, D., Francis, V., Menon, J., Sharma, P., Mathur, A., Bhaskarwar, P., Mardikar, H., Kale, M., Lavhe, P., Anthony, A., Kumbla, M., Francis, J., Kumar, A., Karpuram, M., Kumar, P., Lawande, A., Kulkarni, G., Deokar, M., Kulkarni, R., Kotiwale, V., Krishnan, H., Kishore, R., Kandekar, S., Kandekar, B., Raut, N., Kale, V., Joshi, H., Thomas, R., Joseph, J., Oommen, D., Joseph, S., Pahuja, M., Jain, R., Ghume, A., Hiremath, J., Thakor, G., Hardas, S., Savanth, P., Hadan, S., Singh, P., Gupta, J., Saini, A., Goyal, N., Mali, N., Chopda, M., Karnwal, N., Somaraju, B., Calambur, N., Bhuti, M., Biniwale, A., Rathi, A., Bhargava, V., Solanki, R., Bharani, A., Surushe, S., Benjarge, P., Sheth, T., Banker, D., Reddy, J., Babu, R., Rao, B., Babu, P., Shaikh, A., Avvaru, G., Shree, R., Arora, V., Memon, A., Arneja, J., Ranka, R., Agarwal, D., Abdullakutty, J., Malhan, S., Kincses, M., Vertes, A., Marosi, A., Tomcsanyi, J., Szakal, I., Sipos, T., Ruzsa, D., Simor, T., Bognar, A., Sayour, A., Toth, S. Rostasne, Palinkas, A., Nagy, A., Kolumban, E., Merkely, B., Kiss, K., Medvegy, M., Kiss, T., Matoltsy, A., Karakai, H. Horvathne, Lupkovics, G., Kovacs, Z., Baranyai, M., Kovacs, I., Koczka, M., Jakal, A., Kiss, R., Feil, J. Felfoldine, Kis, E., Kosztyu, M., Kanakaridisz, N., Varga, A., Fiok, J., Szatmari, J., Edes, I., Muskoczki, E., Dioszeghy, P., Almaraz, S. Padilla, Camas, L. Velasquez, Guerra, L., Samayoa, C. Sanchez, Pozuelos, J. Mayen, Sanchez, M., Estrada, M. Rodas, Guevara, S., Lavagnino, A. Ovando, Jimenez, T., Melgar, I. Guzman, Ramirez, V. de Leon, Milla, O. Ayau, Korantanis, K., Pyrgakis, V., Kartsagkoulis, E., Olympios, C., Dimitra, K., Moschos, N., Daskalaki, A., Kifnidis, K., Exarchou, E., Karamitsos, C., Tziortziotis, A., Bourlios, P., Mavronasiou, E., Alexopoulos, D., Winter, K., Wolde, C., Buelow-Johansen, B., Winkelmann, B., Weyland, K., Buchholz, M., Voehringer, Voehringer, Ludwig, I., Veltkamp, R., Zarpentin, C., Taggeselle, J., Stoehring, R., Bonin, K., Spitzer, S., Baylacher, M., Sohn, H., Gold, G., Seibert, H., Hellmers, J., Schreckenberg, A., Schmidt, M., Schmidt, A., Schiewe, C., Dreykluft, K., Ellis, J., Cristaldi, J., Finsterbusch, T., Erenrich, N., Schenkenberger, I., Frommhold, R., Schellong, S., Szymanowski, N., Schaefer, A., Kuehlenborg, A., Rinke, A., Pilipenko, H., Rack, K., Kuhlmann, M., Proskynitopoulos, N., Pohl, W., Lewinsky, D., Piechatzek, R., Raddatz, K., Mueller-Glamann, M., Barbera, S., Muegge, A., Vogt, S., Mitrovic, V., Frahm, E., Meyer-Pannwitt, U., Braemer, U., Meissner, G., Hoefer, K., Maus, O., Wulf, M., Luttermann, M., Venneklaas, U., Lueders, S., Grosse, B., Lohrbaecher-Kozak, I., Bauch, F., Koenig, H., Meusel, P., Kleinecke-Pohl, U., Schoen, B., Jungmair, W., Schmid, S., Junggeburth, J., Fink, P., Horacek, T., Schuppe, M., Hoffmann, S., Dorn, S., Hoffmann, U., Dieckheuer, U., Heuer, H., Peitz, M., Hartmann, A., Otto, A., Grigat, C., Manuela, W., Fuchs, R., Schneider, K., Forck-Boedeker, K., Faghih, M., Herfurth, B., Drescher, T., Kranz, P., Degtyareva, E., Ayasse, D., Daut, W., Kara, M., Contzen, C., Weihrauch, D., Buhr, M., Ladenburger, K., Braun, R., Schnelzer, P., Bouzo, M., Sehr, B., Beyer-Westendorf, J., Vierbeck, S., Berrouschot, J., Dichristin, U., Bernhardt, P., Wurow, A., Al-Zoebi, A., Duprat, C., Roudaut, R., Leparree, S., Poulard, J., Corbut, S., Kacet, S., Deruche, E., Hermida, J., Arfaoui, M., Dinanian, S., El Jarroudi, M., Decoulx, E., Berger, N., Coisne, D., Dias, P., Blanc, J., Berbari, H., Belhassane, A., Boyer, M., Babuty, D., Boursin, P., Amarenco, P., El Jarroudi, F., Agraou, B., Le Heuzey, J., Nappila, H., Virtanen, V., Salminen, O., Rasi, H., Sankari, T., Nyman, K., Viitaniemi, J., Maenpaa, A., Laheaar, M., Lucijanic, T., Lappalainen, T., Jakala, P., Valpas, S., Hussi, E., Kaarleenkaski, S., Huikuri, H., Ratnik, E., Vahula, V., Rajasalu, R., Rosenthal, A., Voitk, J., Paumets, M., Rivis, L., Laane, E., Kolk, R., Stern, A., Kaik, J., Serup-Hansen, K., Wiggers, H., Jakobsen, U., Torp-Pedersen, C., Svenningsen, A., Sand, N., Raae, D., Raymond, I., Petrovic, V., Overgaard, K., Olsen, R., Nielsen, H., Veng-Olsen, T., Iversen, H., Madsen, H., Ibsen, H., Loof, A., Hassager, C., Christensen, L., Christensen, H., Dodt, K., Zidkova, E., Samkova, D., Vodnansky, P., Labrova, R., Spinar, J., Johnson, C., Spacek, R., Slaby, J., Reichert, P., Jirsova, E., Podrazil, P., Pisova, J., Havlova, I., Petrova, I., Peterka, K., Olsr, J., Nechanicky, R., Melichar, M., Krocova, E., Machova, V., Ludka, O., Kvasnicka, J., Kuchar, R., Kovar, P., Kosek, Z., Kostkova, G., Kochrt, M., Kobza, R., Jirmar, R., Jerabek, O., Jelinek, Z., Jarkovsky, P., Jandik, J., Hubac, J., Honkova, M., Gregor, P., Golan, L., Francek, L., Florian, J., Ferkl, R., Elbl, L., Cermak, O., O'Brien, J., Burianova, H., Brtko, M., Kunkelova, V., Berka, L., Brodova, P., Bar, M., Bergovec, M., Vrazic, H., Bakliza, Z., Sutalo, K., Kirner, D., Steiner, R., Cvitkusic Lukenda, K., Samardzic, P., Buksa, B., Knezevic, A., Jaksic Jurinjak, S., Ettinger, N., Shipp, A., Jelic, V., Makar Ausperger, K., Francetic, I., Romic, I., Ferri Certic, J., Tusek, S., Ciglenecki, N., Jeric, M., Car, S., Carevic, V., Bagatin, J., Perdomo Mejia, I., Sanchez Vallejo, G., Gonzales, C., Quintero, A., Fonseca, J., Orozco Linares, L., Lopez Giraldo, D., Moncada Corredor, M., Rivera Rodriguez, E., Manzur, F., Builes, A., Jaramillo Munoz, C., Delgado, P., Hernandez, H., Aldana Diaz, I., Fernandez Ruiz, R., Arroyave, C., Delgado Restrepo, J., Leon Pineda, L., Cano, N., Accini, M., Accini, J., Zhang, Y. L., Zhou, S. X., Li, B. G., Zheng, Z. Q., Wang, J. Q., Zhao, X. L., Han, R. J., Zhao, R. P., Kang, H., Zhang, Z., Lin, Y. N., Zhang, H. Q., Qiang, H., Everhart, B., DeSalle, D., Fahmy, R., Watkins, D., Yuan, Z. Y., Li, L. L., Yu, B., Xu, Y. P., Yin, Y. H., Gao, M., Zheng, Y., Feld, L., Zheng, X., Tameron, A., Feldman, J., Tang, N., Felten, W., Yang, Y. J., Li, A. Y., Yang, K., Liang, Y. Z., Xu, Y. M., Gu, J. Y., Xu, J. H., Li, Y. E., Wu, S. L., Huang, D., Wei, M., Shi, X. J., Wang, G. P., Qi, S. Y., Wang, D. M., Yang, Z. Y., Ma, S. M., Lu, Z. H., Liu, L., Gu, X. J., Liao, D. N., Liu, Y., Prior, J., Fialkow, J., Calvo, M., Li, Z. Q., Liu, B., Finkel, M., Shriver, D., Finkelstein, S., Fischell, T., Drew, B., Fishbein, G., Donahue, S., Flores, E., Slayton, C., Forman, S., Solis, A., Frais, M., Thrope, C., Franco, M., Gentry, P., French, W., Morales, C., Friedlander, I., Smith, K., Gaffney, M., Jones, J., Li, W. M., Kong, Y. Q., Li, T. F., Liu, H., Li, L., Qu, Z., Jiang, X. J., Qiu, Y., Hong, L., You, Z. G., Hong, K., Zhang, P., Fu, G. S., Feng, C., Dong, Y. G., Zhang, X., Chen, X. P., Xie, X. D., Chen, J. Z., Xu, G. L., Bai, F., Grandon Azua, M., Yovaniniz, P., Lara Lara, C., Stockins, B., Campisto, Y., Zapata Staub, J., Potthoff, S., Torres Carrasco, G., Pincetti, C., Carmona Perez, M., Opazo, M., Romero Llamas, R., Martinez, D., Manriquez Silva, L., Manriquez, L., Rebolledo, C., Lopetegui, M., Arratia Diaz, P., Florenzano, F., Parada, A., Corbalan, R., Obreque, C., Cobos, J., Mondaca Mondaca, P., Bugueno, C., Retamal Matus, L., Balboa, W., Mabee, J., Woodford, T., Caterini, T., Wharton, S., Morley, A., Wahby, R., Giesbrecht, L., Velthuysen, G., Teitelbaum, J., Teitelbaum, I., Tremblay, M., Talbot, P., David, D., Talajic, M., Bobbie, C., Syan, G., Kailey, P., Sussman, J., Morissette, A., St-Hilaire, R., Silverio, G., Shu, D., Marchand, C., Rupka, D., Bozek, B., Ricci, J., Nethercott, C., Qureshi, A., Turri, L., Polasek, P., Sardin, V., Pesant, Y., Carroll, L., Parkash, R., Bolton, R., O'Mahony, W., Banville, P., O'Hara, G., Nicholson, R., Lamoureux, U., Garb, J., Najarali, A., Krider, J., Mucha, M., Roth, M., Morrison, D., Morely, A., Mawji, A., Studenikow, E., Maranda, C., Vaillancourt, T., Malette, P., Matthews, J., MacCallum, C., Seib, M., Ma, P., Douglas, S., Luton, R., Roberts, P., Lichtenstein, T., Lam, H., Lam, S., St-Germain, L., Lainesse, A., Dewar, C., Labonte, R., Roy, M., Kouz, S., Perkins, L., Huynh, T., Standring, R., Hoag, G., Ho, V., Ho, K., Scott, L., Heath, J., Hatheway, R., Houbraken, D., Viau, C., Fortin, C., Zondag, M., Eikelboom, J., Dufresne, M., Kubanska, A., du Preez, M., Denis, I., Coutu, B., Masson, C., Costi, P., Gauthier, M., Constance, C., Valley, S., Cleveland, D., Vansickle, L., Chilvers, M., Lepage, C., Otis, J., Cha, J., Hundseth, M., Bose, S., Stafford, C., Bhargava, R., Antle, S., Archibald, J., Manoylov, E., Kitova, M., Tzekova, M., Tumbeva, D., Tumbev, H., Nyagina, M., Todorov, G., Momchilova-Lozeva, D., Staneva, A., Vasilev, I., Popov, A., Milusheva, T., Petranov, S., Kostov, K., Pencheva, G., Vasilev, D., Nikolov, F., Stoyanovski, V., Mincheva, V., Miteva, B., Mihov, A., Manolova, A., Kamenova, P., Hergeldjieva, V., Kinova, E., Goudev, A., Kostova, E., Georgiev, B., Gergova, V., Donova, T., Milcheva, N., Denchev, S., Parishev, G., Chompalova, B., Zimmermann, E. Burger, Zimmermann, S., Almeida, M., Boas, F. Villas, Lustosa, E., Sobral Filho, D., Carraro, A., Simoes, M., Vicente, C., Saraiva, J., do Val, R., Sampaio, R., Pagnan, L. Goncalves, dos Santos, F. Rossi, Rodrigues, D., Rodrigues, A., Rocha, M. Rubia, Rodrigues, L., Barros, R., Rocha, J., Leipelt, J., Katz Weiand, L. Reis, Avellar, K., Reis, G., Gozalo, A., Almeida, J. Pimenta, Luiz, R. Osorio, Leaes, P., Morales, K., Sebba Barroso de Souza, W. Kunz, Radaelli, G., Kalil, C., Almeida, A., Kaiser, S., Cury, C., Jorge, J., Pereira, L., Jaeger, C., Ninho, L., Guimaraes, A., Gomes, A., Gomes, M., Pereira, G., Gagliardi, R., Daitz, C., Finimundi, H., Araujo, E., Ferreira, L., Seroqui, M., Saporito, W. Faustino, Morgado, S., Dutra, O., Laimer, R., Duda, N., Pereira, V., De Patta, M., Barroso, D., Costantini, C., Silva, J., Chaves Junior, H., Fleck, N., Brondani, R., Cunha, S., Botelho, R., Sehnem, E., Precoma, D. Bertolim, Ferraz, R. Franchin, Alves da Costa, F. Augusto, Motta, C., Atie, J., de Melo, R. Ferreira, Lotufo, P. Andrade, Coutinho, E., Vincenzo de Paola, A. Amato, Denie, D., and Wollaert, B.
- Subjects
Male ,medicine.medical_specialty ,medicine.drug_mechanism_of_action ,medicine.drug_class ,Pyridines ,Factor Xa Inhibitor ,Infarction ,chemistry.chemical_compound ,Double-Blind Method ,Edoxaban ,Internal medicine ,Atrial Fibrillation ,medicine ,Humans ,Myocardial infarction ,cardiovascular diseases ,Stroke ,Aged ,Advanced and Specialized Nursing ,Dose-Response Relationship, Drug ,business.industry ,Anticoagulant ,Warfarin ,Anticoagulants ,Atrial fibrillation ,Middle Aged ,medicine.disease ,Thiazoles ,Treatment Outcome ,chemistry ,Anesthesia ,Cardiology ,Female ,Neurology (clinical) ,Cardiology and Cardiovascular Medicine ,business ,medicine.drug - Abstract
Background and Purpose— The once-daily oral factor Xa inhibitor, edoxaban, is as effective as warfarin in preventing stroke and systemic embolism while decreasing bleeding in a phase III trial of patients with atrial fibrillation at moderate–high stroke risk. Limited data regarding cerebrovascular events with edoxaban were reported previously. Methods— We analyzed the subtypes of cerebrovascular events in 21 105 patients participating in Effective Anticoagulation with Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in Myocardial Infarction 48 (ENGAGE AF-TIMI 48) comparing outcomes among patients randomized to warfarin versus 2 edoxaban regimens (high dose, low dose). The primary end point for this prespecified analysis of cerebrovascular events was all stroke (ischemic plus hemorrhagic), defined as an abrupt onset of focal neurological deficit because of infarction or bleeding with symptoms lasting ≥24 hours or fatal in Results— Patients randomized to high-dose edoxaban had fewer strokes on-treatment (hazard ratio, 0.80; 95% confidence interval, 0.65–0.98) than warfarin (median time-in-therapeutic range, 68.4%); patients in the low-dose edoxaban group had similar rates (hazard ratio, 1.10 versus warfarin; 95% confidence interval, 0.91–1.32). Rates of ischemic stroke or transient ischemic attack were similar with high-dose edoxaban (1.76% per year) and warfarin (1.73% per year; P =0.81), but more frequent with low-dose edoxaban (2.48% per year; P Conclusions— In patients with atrial fibrillation, once-daily edoxaban was as effective as warfarin in preventing all strokes, with significant reductions in various subtypes of intracranial bleeding. Ischemic cerebrovascular event rates were similar with high-dose edoxaban and warfarin, whereas low-dose edoxaban was less effective than warfarin. Clinical Trial Registration— URL: http://www.clinicaltrials.gov . Unique identifier: NCT00781391.
- Published
- 2014
36. Possibilities of Alfalfa Cultivation Intensification and Biologization
- Author
-
Ussipbayev, Nurlan B., primary and Sadvakassov, Serik S., additional
- Published
- 2016
- Full Text
- View/download PDF
37. INFLUENCE OF POLYACRYLIC ACID HYDROGEL’S SWELLING DEGREE ON SORPTION ABILITY OF INTERGEL SYSTEM POLYACRYLIC ACID HYDROGEL – POLY-4-VINYLPYRIDINE HYDROGEL IN RELATION TO NEODYMIUM IONS.
- Author
-
Jumadilov, Talkybek K., Kondaurov, Ruslan G., Kozhabekov, Serik S., Tolegen, Gauhar A., Eskalieva, Gauhar K., and Khakimzhanov, Sergali A.
- Subjects
POLYACRYLIC acid ,OCEAN waves ,ELECTRIC conductivity ,SORPTION ,NEODYMIUM ,IONS ,RARE earth ions - Abstract
Mutual activation of polyacrylic acid hydrogel (gPAA) and poly-4-vinylpyridine hydrogel (gP4VP) in an intergel system in a neodymium nitrate solution was studied. The dependencies of the latter swelling degree, specific electric conductivity and pH on the hydrogels molar ratios and time were studied. It was found that the more rare-crosslinked hydrogel of the polyacrylic acid provided faster gPAA and gP4VP mutual activation in the intergel system and an increased extraction degree of Nd
3+ ions. The maximum extraction degree of Nd3+ ions was observed at g PAA:g P4VP = 3:3 ratio. It was 94.2 % when gPAA swelling degree was 24.2 g/g and 95.7 % when gPAA swelling degree was 61.9 g/g. The extraction degree of the individual hydrogels of polyacrylic acid and poly-4-vinylpyridine was 58.2 % (when gPAA swelling degree was 24.2 g/g), 62.0 % (when gPAA swelling degree was 61.9 g/g) and 54.6 %, respectively. The results obtained point to a possible application of the intergel system based on gPAA and gP4VP for extraction of rare-earth elements from industrial solutions. [ABSTRACT FROM AUTHOR]- Published
- 2018
38. 443 Lipoprotein-containing immune complexes in patients with ischemic heart disease during chronic heart failure progression
- Author
-
SERIK, S, primary
- Published
- 2004
- Full Text
- View/download PDF
39. DEVELOPMENT OF INTEGRATION PROCESSES OF THE CENTRAL ASIAN COUNTRIES IN THE GLOBALIZATION OF THE WORLD ECONOMY.
- Author
-
Nabiev, Erboz N., Gomarova, Aigul M., and Daribekov, Serik S.
- Subjects
INTERNATIONAL economic integration ,INTEGRATION (Theory of knowledge) ,INTERNATIONAL economic relations ,ECONOMIC globalization ,NATIONAL interest - Abstract
This article describes the priorities and perspectives of integrative interaction, the dynamics of integration processes of the Central Asian countries in accordance with the national interests within the framework of the CAC Organization on the basis of international experience and analysis of integration processes in Central Asia. [ABSTRACT FROM AUTHOR]
- Published
- 2016
40. Safety and efficacy of flow diverter stents in the treatment of bifurcation cerebral aneurysms: single-center experience.
- Author
-
Makhambetov Y, Maidan A, Nurimanov C, Kaliyev A, Kunakbayev B, Nurakay N, Dyussembayev S, and Makhambetov N
- Abstract
Purpose: The use of flow diverter (FD) stents is continually expanding. Aneurysms on arterial bifurcation typically have an undesirable anatomical form, are frequently wide-necked, and include one or more side-branch arteries. In recent years, the off-label use of flow diversion in treating intracranial aneurysms beyond the internal carotid artery has become increasingly popular. This study reports our center's initial experience treating bifurcation aneurysms with FD devices, documenting occlusion outcomes using the O'Kelly-Marotta and modified Cekirge-Saatci scales, as well as the safety of FD usage in bifurcation locations., Methods: This retrospective, single-center study analyzed a prospectively maintained database of patients with cerebral aneurysms treated endovascularly. The study identified bifurcation aneurysms that were treated between January 2019 and May 2022 by placing an FD device covering the neck of the aneurysm., Results: Our short series suggests that flow diversion is a viable therapeutic option for bifurcation aneurysms with favorable angiographic outcomes., Conclusion: In highly selective cases, flow diversion may be considered for treating bifurcation aneurysms in patients who will undergo follow-up examinations in the future., Clinical Significance: Flow diversion has emerged as a valuable technique in the management of bifurcation aneurysms, offering the potential for satisfactory occlusion and long-term outcomes.
- Published
- 2024
- Full Text
- View/download PDF
41. Temporal dynamics of negative emotional memory reprocessing during sleep.
- Author
-
Tabarak S, Zhu X, Li P, Weber FD, Shi L, Gong Y, Yuan K, Bao Y, Fan T, Li S, Shi J, Lu L, and Deng J
- Subjects
- Humans, Male, Young Adult, Female, Adult, Electroencephalography, Memory physiology, Adolescent, Emotions physiology, Sleep physiology, Transcranial Direct Current Stimulation, Memory Consolidation physiology
- Abstract
Memory reprocessing during sleep is a well-established phenomenon in numerous studies. However, it is unclear whether the intensity of memory reprocessing is consistently maintained throughout the night or exhibits dynamic changes. This study investigates the temporal dynamics of negative emotional memory reprocessing during sleep, with a specific focus on slow oscillation (SO)-spindle coupling and its role in memory reprocessing. In the first experiment (N = 40, mean age = 22.5 years), we detected the negative emotional memory reprocessing strength in each sleep cycle, we found that the 2nd sleep cycle after negative emotional memory learning constitute the most sensitive window for memory reprocessing, furthermore, SO-spindle coupling signals in this window plays a role in stabilizing negative emotional memory. To verify the role of SO-spindle coupling in negative emotional memory reprocessing, we utilized transcranial alternating current stimulation (tACS) to disrupt SO-spindle coupling during the 2
nd sleep cycle (N = 21, mean age = 19.3 years). Notably, the outcomes of the tACS intervention demonstrated a significant reduction in the recognition of negative emotional memories. These findings offer new insights into the mechanisms that regulate emotional memory consolidation during sleep and may have implications for addressing psychiatric disorders associated with pathological emotional memory., (© 2024. The Author(s).)- Published
- 2024
- Full Text
- View/download PDF
42. Exploring the Antibacterial and Regenerative Properties of a Two-Stage Alginate Wound Dressing in a Rat Model of Purulent Wounds.
- Author
-
Atepileva A, Ogay V, Kudaibergen G, Kaukabaeva G, Nurkina A, Mukhambetova A, Balgazarov S, Batpen A, Saginova D, Ramazanov Z, Balgazarov A, and Akhmetkarimova Z
- Abstract
Chronic wounds complicated by infection pose significant clinical challenges, necessitating comprehensive treatment approaches. The widespread use of antibiotics has led to resistant microorganisms, complicating traditional therapies. This study aims to develop and evaluate modified alginate wound dressings with enhanced antimicrobial and regenerative properties. Alginate dressings were synthesized with silver nanoparticles, cefepime, and fibroblast growth factor-2 (FGF-2). The two-stage therapy involved an initial antibacterial dressing followed by a regenerative dressing. In vitro tests demonstrated high antibacterial activity, with maximum inhibition zones for P. aeruginosa (41.3 ± 0.4 mm) and S. aureus (36.6 ± 1.8 mm). In vivo studies on rats with purulent wounds showed significant healing progression in the experimental group. Histological analysis revealed complete re-epithelialization, thicker neoepithelium, dense collagen deposition, and minimal inflammation in treated wounds. These findings suggest that the modified alginate dressings significantly enhance the reparative process and are promising for treating chronic infected wounds in both veterinary and medical practices.
- Published
- 2024
- Full Text
- View/download PDF
43. Efficiency and safety of continuous theta burst stimulation for primary insomnia: A randomized clinical trial.
- Author
-
Zhu X, Tabarak S, Que J, Yan W, Lin X, Liu X, Chen W, Shi J, Deng J, and Lu L
- Abstract
Objectives: Primary insomnia is a substantial public health burden, but current treatments for this disorder have limited effectiveness and adherence. Herein, we aimed to investigate the efficacy and safety of continuous theta burst stimulation (cTBS) for the treatment of primary insomnia., Methods: This two-armed, randomized, sham-controlled trial was conducted at Peking University Sixth Hospital and local community clinics. A total of 46 patients with primary insomnia were recruited and randomly allocated to either the cTBS group or sham group. Forty-one patients completed 10 sessions of cTBS or sham intervention and follow-up assessments., Results: After the intervention, the severity of insomnia was significantly lower in the cTBS group than in the sham group, with a large effect size (Cohen's d = -1.938). Additionally, 52.4 % of patients in the cTBS group achieved a response (Insomnia Severity Index score reduction ≥8), whereas only 4 % of patients in the sham group achieved a response. The duration of objective total sleep time and slow-wave sleep were higher in the cTBS group than in the sham group. The degree of anxiety was lower in the cTBS group than in the sham group. There were no significant differences in depression, sleepiness, or cognitive function between the cTBS and sham groups. During follow-up, the sleep quality of the cTBS group significantly improved and remained stable at the 6-month follow-up., Conclusion: In this randomized clinical trial, cTBS improved insomnia symptoms and was generally well tolerated, thus supporting the further development of cTBS for the treatment of primary insomnia., Competing Interests: Declaration of competing interest The authors report that they have no financial conflicts of interest with respect to the content of this manuscript., (Copyright © 2024. Published by Elsevier B.V.)
- Published
- 2024
- Full Text
- View/download PDF
44. Trends in Stage-Specific Kidney Cancer Incidence in Kazakhstan, 2005-2019.
- Author
-
Igissin N, Dyakov S, Telmanova Z, Kudaibergenova I, Ayaganov S, Turebayev D, Jexenova A, Igissinova GS, Maukayeva S, Lust V, Grigorevsky V, Shelestyuk A, Syzdykov N, Shishkin I, and Bilyalova Z
- Subjects
- Humans, Kazakhstan epidemiology, Female, Male, Retrospective Studies, Incidence, Middle Aged, Aged, Adult, Aged, 80 and over, Follow-Up Studies, Prognosis, Young Adult, Adolescent, Child, Child, Preschool, Kidney Neoplasms epidemiology, Kidney Neoplasms pathology, Neoplasm Staging
- Abstract
Objective: The aim is to analyze the incidence of kidney cancer over a 15-year period, considering factors such as stage, age, sex, and morphological verification in the regional context in Kazakhstan., Methods: The retrospective study was done using descriptive and analytical methods of oncoepidemiology. The extensive, crude and age-specific incidence rates are determined according to the generally accepted methodology used in sanitary statistics. The data were used to calculate the average percentage change (APС) using the Joinpoint regression analysis to determine the trend over the study period., Results: Among the meticulously documented 15,277 cases, a conspicuous male predominance was noted, comprising 53.7% of cases compared to 46.3% in females, with peak incidences observed within the 50-69 age cohorts. The average age at diagnosis exhibited a progressive rise over the study period, with discernible variations observed in age-specific incidence rates, particularly pronounced within the 60-84 age brackets. Noteworthy temporal trends indicated a consistent uptick in crude incidence rates, with distinct regional disparities manifesting higher rates in northern regions relative to their southern and western counterparts. Stratification by cancer stage unveiled a significant surge in stages I-II cases alongside a concomitant decrement in stage III incidences, complemented by reductions in stage IV occurrences and instances of unspecified disease stages. Morphological verification rates displayed regional variations, with an overarching ascending trajectory across most regions, albeit exceptions noted, notably in the Kyzylorda region., Conclusion: Our study identified a rise in kidney cancer incidence in Kazakhstan, likely reflecting global trends driven by increased risk factor exposure and incidental imaging findings. Regional disparities and varied stage distributions highlight the complexity of kidney cancer epidemiology. Despite advancements in early detection, delayed diagnosis persists, necessitating improved surveillance and diagnostic practices.
- Published
- 2024
- Full Text
- View/download PDF
45. Renal angiomyolipoma rupture in the immediate postoperative period following caesarean section.
- Author
-
Shegenov G, Iskakov S, and Bilyalova G
- Subjects
- Humans, Female, Pregnancy, Rupture, Spontaneous etiology, Adult, Nephrectomy adverse effects, Postoperative Complications etiology, Pregnancy Complications, Neoplastic surgery, Postoperative Period, Cesarean Section adverse effects, Angiomyolipoma surgery, Kidney Neoplasms surgery
- Abstract
Renal angiomyolipoma (rAML) is a rare benign tumour primarily affecting women due to hormonal influences, with accelerated growth observed during pregnancy. This case report presents a multigravida woman in her mid-20s at 37 weeks of gestation with stable vital signs and normal physical examination findings, except for swelling in the lower extremities. Following caesarean section delivery, she developed flank pain and haematuria in the immediate postoperative period. Emergency surgery revealed a ruptured rAML, resulting in unstable haemodynamics and significant blood loss. A multidisciplinary team performed a left radical nephrectomy to control bleeding. The patient required transfusions, ventilation and postoperative antibiotic therapy. This case underscores the importance of considering rAML rupture in the immediate postoperative period following caesarean section, highlighting the need for prompt evaluation in pregnant women with a history of urologic disorders., Competing Interests: Competing interests: None declared., (© BMJ Publishing Group Limited 2024. No commercial re-use. See rights and permissions. Published by BMJ.)
- Published
- 2024
- Full Text
- View/download PDF
46. Motivational determinants of athletes' self-realisation depending on their professional qualification.
- Author
-
Krasmik Y, Aimaganbetova O, Iancheva T, Zhantikeyev S, Lashkova E, Makhmutov A, and Rakhmalin B
- Subjects
- Humans, Adult, Male, Female, Young Adult, Kazakhstan, Surveys and Questionnaires, Para-Athletes psychology, Motivation, Athletes psychology, Self Concept
- Abstract
Background: In the contemporary era, there is a growing emphasis on understanding the self-realization of personality, encompassing individual-psychological traits, abilities, knowledge, skills, and motivation, extensively studied in psychology. Notably, limited attention has been given to exploring motivational determinants influencing athlete self-realization based on their professional qualifications. This gap is particularly pertinent in Kazakhstan, where significant efforts are directed towards athlete preparation., Methods: Employing a systemic approach by Bagadirova and Kudinov, the study views athlete self-realization as a multi-level phenomenon with interconnected components. A total of 180 athletes participated, including 60 professionals (average age 23.9), 60 amateurs (average age 31.1), and 60 Paralympians (average age 24.4). The methodological toolkit comprises four diagnostic techniques: E.A. Kalinin's "Motives of Sports Activities" (MSA) questionnaire, S. Maddi's resilience test adapted by D.A. Leontiev and E.I. Rasskazova, and S.I. Kudinov's multidimensional questionnaire on self-realization., Results: Significant differences in motivational determinants and self-realization attitudes emerge across athlete groups based on their sports qualifications. Noteworthy aspects include declining in motivation among professional athletes of masters of sports and masters of sports of international class, and rigidity in life resilience among Paralympic athletes. Overall, self-realization levels are not high, with extremely low levels of professional self-realization in all three athlete categories., Conclusions: The study's scientific novelty lies in systematically organizing knowledge on fundamental motivational determinants impacting athlete self-realization according to professional qualifications. This research addresses the acute shortage of psychological studies in sports psychology for Kazakhstan, which is still in its early stages. The findings underscore the need for targeted interventions by coaches and sports psychologists to enhance motivation levels, especially among elite athletes, and foster resilience, particularly in Paralympic athletes, ultimately advancing the field in the country., (© 2024. The Author(s).)
- Published
- 2024
- Full Text
- View/download PDF
47. Study of the stress in adults diagnosed with meningioma: Insights from a tertiary neurosurgical hospital.
- Author
-
Menlibayeva K, Nurimanov C, Nuradilov S, and Akshulakov S
- Subjects
- Humans, Case-Control Studies, Surveys and Questionnaires, Male, Female, Adult, Middle Aged, Aged, Kazakhstan, Stress, Psychological complications, Meningioma complications, Meningioma psychology, Brain Neoplasms etiology, Brain Neoplasms psychology
- Abstract
Background: Meningiomas are the most common type of primary brain tumor, originating from the meninges - the protective membranes that surround the brain and spinal cord. Several well-studied risk factors for meningiomas include gender, age, radiation exposure, genetic factors, and hormonal factors. Moreover, the influence of a person's psycho-emotional stateon their overall health and mental well-being, specifically stress, iscurrently a significant and relevant topic of discussion., Aims: This case-control study aimed to study the association between perceived stress, chronic stress, and meningioma in adult patients., Methods and Results: The study included cases, which comprised adult patients with histologically confirmed meningioma, and controls, consisting of adult patients with no history of brain cancer. Data collection involved the use of three types of questionnaires. The first questionnaire focused on patients' personal information, geographic factors, and lifestyle habits. Two additional questionnaires "The Perceived Stress Scale" and "The Chronic Stress Scale" were employed to assess perceived stress and chronic stress. The questioning was conducted by a neurologist. Microsoft Excel and Stata 14 were used for the data analysis. Overall, 148 questionnaires were completed and included in the analyses. The average age of participants was 45.60 ± 13.90 years. Females outnumbered males in both groups. Patients with meningioma diagnosis had a higher level of perceived high stress compared to those without meningioma (p = .045). Respondents without a diagnosis of meningioma have reported having more chronic stress in general and ambient problems (p = .004), financial issues (p = .006), work (p < .001), non-employment (p = .008), love and marriage (p < .001), isolation (p < .001), and residence (p < .001). Patients with meningioma, however, had less chronic stress compared to meningioma-free patients., Conclusion: This study revealed no discernible connection between stress and meningioma within our study sample. Further research with matched case-control methodology with a larger sample size is warranted to thoroughly evaluate the potential role of stress in patients with meningioma., (© 2024 The Author(s). Cancer Reports published by Wiley Periodicals LLC.)
- Published
- 2024
- Full Text
- View/download PDF
48. Assessing the role of sustainability competencies in enhancing psychological first aid effectiveness for disaster responders in Fiji.
- Author
-
Nair M and Meirmanov S
- Subjects
- Humans, Fiji, Female, Male, Cross-Sectional Studies, Adult, Middle Aged, Surveys and Questionnaires, Emergency Responders psychology, Emergency Responders education, Professional Competence, Disasters, First Aid
- Abstract
Background: Psychological first aid (PFA) is essential for mental health and wellbeing after traumatic events. Integrating competency-based outcomes is crucial with the increasing demand for effective psychological first-aid interventions. This study examines the correlation between sustainability competencies and PFA principles within Fiji's disaster responder's context., Method: The research was guided by a theoretical framework based on a comprehensive review of sustainability competencies and PFA principles. A cross-sectional survey assessed the importance of sustainability competencies in disaster responders to deliver PFA effectively. The survey used a stratified random sampling method to get diverse PFA-trained participants (66%) and non-PFA trained (34%), aiming to understand how these competencies can impact PFA success in various disaster situations. The survey, encompassing various domains of disaster response and a diverse range of respondents age, gender, and years of experience, employed the Likert scale to assess the importance of competencies such as integrated problem-solving, strategic, systems thinking, self-awareness, normative, collaboration, anticipatory, and critical thinking., Results: The study involved 49 PFA-trained participants (55% female, 45% male) and 15 non-PFA-trained participants (53% female, 46% male), excluding 10 responses from the latter group due to ambiguous answers to critical questions. The correlation between age, experience, and the valuation of professional competencies among disaster responders indicates that disaster responders, with extensive experience and PFA training, rated competencies as "important," reflecting a perspective shaped by long-term career development and practical experiences. Equally, younger and early career responders emphasize competencies as "very important," indicating an initial recognition of their significance. The appraisal patterns across different age groups, especially among those with PFA training, suggest a tendency to moderate assessments of competency importance with increasing experience. Statistical analysis, including mean, median, standard deviation, and variance, provided a detailed understanding of the data, underscoring competencies like self-awareness in both data sets and integrated problem-solving and collaboration within PFA-trained responders as the key for effective PFA interventions., Conclusion: The study underlines the critical need to integrate sustainability competencies into the PFA curriculum in Fiji's unique sociocultural context. This interplay between age, experience, and competency assessment stresses the diverse factors influencing perceptions in the disaster response field beyond experience alone. The results show that sustainability competencies are the ultimate to the effectiveness of PFA measurement and interventions. The research lays the foundation for future studies to develop validated tools for assessing sustainable competencies in different cultural contexts, thereby improving the effectiveness of PFA in disaster management. Integrating these competencies into PFA training could significantly strengthen PFA intervention and competency-based evaluation., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2024 Nair and Meirmanov.)
- Published
- 2024
- Full Text
- View/download PDF
49. Multi-genome comparisons reveal gain-and-loss evolution of anti-Mullerian hormone receptor type 2 as a candidate master sex-determining gene in Percidae.
- Author
-
Kuhl H, Euclide PT, Klopp C, Cabau C, Zahm M, Lopez-Roques C, Iampietro C, Kuchly C, Donnadieu C, Feron R, Parrinello H, Poncet C, Jaffrelo L, Confolent C, Wen M, Herpin A, Jouanno E, Bestin A, Haffray P, Morvezen R, de Almeida TR, Lecocq T, Schaerlinger B, Chardard D, Żarski D, Larson WA, Postlethwait JH, Timirkhanov S, Kloas W, Wuertz S, Stöck M, and Guiguen Y
- Subjects
- Animals, Male, Female, Perches genetics, Phylogeny, Receptors, Peptide genetics, Genome, Receptors, Transforming Growth Factor beta, Sex Determination Processes genetics, Evolution, Molecular
- Abstract
Background: The Percidae family comprises many fish species of major importance for aquaculture and fisheries. Based on three new chromosome-scale assemblies in Perca fluviatilis, Perca schrenkii, and Sander vitreus along with additional percid fish reference genomes, we provide an evolutionary and comparative genomic analysis of their sex-determination systems., Results: We explored the fate of a duplicated anti-Mullerian hormone receptor type-2 gene (amhr2bY), previously suggested to be the master sex-determining (MSD) gene in P. flavescens. Phylogenetically related and structurally similar amhr2 duplicates (amhr2b) were found in P. schrenkii and Sander lucioperca, potentially dating this duplication event to their last common ancestor around 19-27 Mya. In P. fluviatilis and S. vitreus, this amhr2b duplicate has been likely lost while it was subject to amplification in S. lucioperca. Analyses of the amhr2b locus in P. schrenkii suggest that this duplication could be also male-specific as it is in P. flavescens. In P. fluviatilis, a relatively small (100 kb) non-recombinant sex-determining region (SDR) was characterized on chromosome 18 using population-genomics approaches. This SDR is characterized by many male-specific single-nucleotide variations (SNVs) and no large duplication/insertion event, suggesting that P. fluviatilis has a male heterogametic sex-determination system (XX/XY), generated by allelic diversification. This SDR contains six annotated genes, including three (c18h1orf198, hsdl1, tbc1d32) with higher expression in the testis than in the ovary., Conclusions: Together, our results provide a new example of the highly dynamic sex chromosome turnover in teleosts and provide new genomic resources for Percidae, including sex-genotyping tools for all three known Perca species., (© 2024. The Author(s).)
- Published
- 2024
- Full Text
- View/download PDF
50. Reducing Heavy Metal Contamination in Soil and Water Using Phytoremediation.
- Author
-
Zhakypbek Y, Kossalbayev BD, Belkozhayev AM, Murat T, Tursbekov S, Abdalimov E, Pashkovskiy P, Kreslavski V, Kuznetsov V, and Allakhverdiev SI
- Abstract
The increase in industrialization has led to an exponential increase in heavy metal (HM) soil contamination, which poses a serious threat to public health and ecosystem stability. This review emphasizes the urgent need to develop innovative technologies for the environmental remediation of intensive anthropogenic pollution. Phytoremediation is a sustainable and cost-effective approach for the detoxification of contaminated soils using various plant species. This review discusses in detail the basic principles of phytoremediation and emphasizes its ecological advantages over other methods for cleaning contaminated areas and its technical viability. Much attention has been given to the selection of hyperaccumulator plants for phytoremediation that can grow on heavy metal-contaminated soils, and the biochemical mechanisms that allow these plants to isolate, detoxify, and accumulate heavy metals are discussed in detail. The novelty of our study lies in reviewing the mechanisms of plant-microorganism interactions that greatly enhance the efficiency of phytoremediation as well as in discussing genetic modifications that could revolutionize the cleanup of contaminated soils. Moreover, this manuscript discusses potential applications of phytoremediation beyond soil detoxification, including its role in bioenergy production and biodiversity restoration in degraded habitats. This review concludes by listing the serious problems that result from anthropogenic environmental pollution that future generations still need to overcome and suggests promising research directions in which the integration of nano- and biotechnology will play an important role in enhancing the effectiveness of phytoremediation. These contributions are critical for environmental scientists, policy makers, and practitioners seeking to utilize phytoremediation to maintain the ecological stability of the environment and its restoration.
- Published
- 2024
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.