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INTRODUCTION: There are several studies about the mortality of the CABG patients with the importance of the inflammation. The aim of our study was to evaluate the relationship between RDW and in-hospital mortality in CABG patients. METHODS: A total of 346 patients undergoing coronary artery bypass grafting operation were analyzed for our study. Pre-operative 2 ml blood sample was put into tubes for evaluation all patients complete blood count. All patients underwent same anesthesia protocol. The type of CABG procedure (off-pump vs on-pump CABG) was determined by the operation team. RESULTS: There was ten patients died in-hospital period (Group 1) and three hundred and thirty-six patients lived during in hospital follow up (Group 2). WBC (10.8 ± 5.2 x 103 vs 7.9 ± 2.2 x 103 p: 0.04), Neutrophil (7.3 ± 3 x 103 vs 5.1 ± 2 x 103 p: 0.03), N/L Ratio (4.8 ± 2.6 % vs 2.7 ± 1.6 % p: 0.01) and RDW (14.8 ± 1.6 % vs 13.9 ± 6.6 %, p: 0.002) values were higher in group 1 than group 2, respectively. A logistic multivariate regression analysis showed that only RDW (OR 1.860, 95% CI 1.105-3.132; p: 0.02) was an independent predictor of the development of mortality in-hospital period in CABG patients. DISCUSSION AND CONCLUSION: To our knowledge, this is the first report of an association between RDW and the development postoperative mortality in CABG patients.

OBJECTIVE Heart failure (HF) has a high prevalence and mortality rate in elderly patients; however, there are few studies that have focused on patients older than 80 years. The aim of this study is to describe and compare the age-specific demographics and clinical features of Turkish elderly patients with HF who were admitted to cardiology clinics. METHODS The Epidemiology of Cardiovascular Disease in Elderly Turkish population (ELDER-TURK) study was conducted in 73 centers in Turkey, and it recruited a total of 5694 patients aged 65 years or older. In this study, the clinical profile of the patients who were aged 80 years or older and those between 65 and 79 years with HF were described and compared based on the ejection fraction (EF)-related classification: HFrEF and HFpEF (is considered as EF: ≥50%). RESULTS A total of 1098 patients (male, 47.5%; mean age, 83.5+-3.1 years) aged ≥80 years and 4596 patients (male, 50.2 %; mean age, 71.1+-4.31 years) aged 65-79 years were enrolled in this study. The prevalence of HF was 39.8% for patients who were ≥80 years and 27.1% for patients 65-79 years old. For patients aged ≥80 years with HF, the prevalence rate was 67% for hypertension (HT), 25.6% for diabetes mellitus (DM), 54.3% for coronary artery disease (CAD), and 42.3% for atrial fibrilation. Female proportion was lower in the HFrEF group (p=0.019). The prevalence of HT and DM was higher in the HFpEF group (p

The study aimed to examine the association between thoracic periaortic fat tissue volume and the long-term incidence of major adverse cardiovascular events.This retrospective cohort study included 433 consecutive patients (372 male and 61 female). Periaortic fat tissue volume was measured via electrocardiogram-gated 64-multidetector computed tomography. The patients were evaluated on an average 3 years of follow-up for major adverse cardiovascular events. The patients were divided into groups according to the presence of major adverse cardiovascular events.Major adverse cardiovascular events were noted in 44 (10.2 %) patients during follow-up. Periaortic fat tissue volume was significantly higher in the major adverse cardiovascular events (+) group (35.4 ± 26.1 cm(3) vs. 24.1 ± 14.9 cm(3), P = 0.001). The logistic regression model showed that periaortic fat tissue volume (hazard ratio: 1.03; 95 % CI: 1.01-1.05; P = 0.001), the glomerular filtration rate (hazard ratio: 0.98; 95 % CI: 0.96-0.99; P = 0.03), and male gender (hazard ratio: 4.76; 95 % CI: 1.08-20.90; P = 0.04) were independent predictors of major adverse cardiovascular events.Thoracic periaortic fat tissue volume may be considered a useful new parameter for predicting major adverse cardiovascular events.

ObJectIVe: Renal artery stenosis (RAS) is emerging one of the cause of chronic renal failure and end-stage renal disease. The vast majority of cases in elderly are due to atherosclerotic disease. The prevalence of RAS in several population studies varies considerably. The study aimed to examine the frequency and risk factors of atherosclerotic critical RAS in patients with coronary artery disease.

PubMed ID: 28238569, Objective No studies have been conducted in Turkey to compare the quality of stroke prevention therapies provided in different healthcare settings in patients with atrial fibrillation (AF). Therefore, we aimed to evaluate possible differences between secondary (SH) and tertiary hospital (TH) settings in the effectiveness of implementing AF treatment strategies. Methods Baseline characteristics of 6273 patients with non-valvular AF enrolled in the RAMSES (ReAl-life Multicentre Survey Evaluating Stroke Prevention Strategies in Turkey) study were compared. Results Of the study population, 3312 (52.8%) patients were treated in THs and 2961 (47.2%) patients were treated in SHs. Patients treated in the SH setting were older (70.8 ± 9.8 vs. 68.7 ± 11.4 years, p

Stent dislodgement over the delivery system is an important and serious complication of percutaneous coronary revascularisation. Several methods have been described previously for the treatment of stent dislodgement. We herein report a case of balloon rupture during stenting that was not deployed properly. The same-sized balloon was used for re-implantation without any complications.

Incidence of post-infarction left ventricular (LV) thrombus is reduced by modern methods of revascularization and treatment with intensive antithrombotic agents. LV thrombus may be an important cause of morbidity and mortality due to relatively high risk of embolization. Therefore, the diagnosis and appropriate management is crucial. The paper introduces a successful treatment of massive, mobile LV thrombus originating from the apical aneurysm and extending to the left ventricular outflow tract.

Angiographic detection of critical stenosis of left main coronary artery (LMCA) dramatically alters the patient's treatment approach. Therefore it should be examined further. This image of the LMCA may be due to sharp angulation, catheter-induced spasm or the relative stenosis due to ectatic LMCA. Operators can be avoided unnecessary revascularization procedures with further investigation. We report the image of angiographically severe stenosis of the LMCA due to a sharp angulation.

Objective: Heart rate recovery (HHR) after exercise is a function of vagal reactivation. This study aimed to evaluate HHR index in patients with erectile dysfunction. Methods: Men over the age of 18 years who were diagnosed with erectile dysfunction were included in the study. Ninety patients with erectile dysfunction (mean age=56.1±8.3 years) and 50 healthy subjects as controls (mean age=53.1±10.4 years) were compared. The erectile status of patients was evaluated using the sexual health inventory for men questionnaire. Basal electrocardiography, echocardiography, and treadmill exercise testing were performed in all patients and controls. The HHR index was defined as the reduction in heart rate from the rate at peak exercise to the rate at the first minute (HRR1), second minute (HRR2), third minute (HRR3), and fifth minute (HRR5) after terminating exercise stress testing. An independent sample t-test, Pearson correlation coefficient test, linear multivariate regression analysis, and receiver operating characteristic curve analysis were used for statistical assessment. Results: All HHR indices were found to be significantly decreased in patients with erectile dysfunction (p

[1] Petta S, Argano C, Colomba D, Camma C, Marco VD, Cabibi D, et al. Epicardial fat, cardiac geometry and cardiac function in patients with non-alcoholic fatty liver disease: association with the severity of liver disease. J Hepatol 2015;62: 928–933. [2] Chiang JK, Koo M, Kuo TB, Fu CH. Association between cardiovascular autonomic functions and time to death in patients with terminal hepatocellular carcinoma. J Pain Symptom Manage 2010;39:673–679. [3] Liu YC, Hung CS, Wu YW, Lee YC, Lin YH, Lin C, et al. Influence of non-alcoholic fatty liver disease on autonomic changes evaluated by the time domain, frequency domain, and symbolic dynamics of heart rate variability. PLoS One 2013;8:e61803. [4] Zhou Q, Zhang L, Wang K, Xu X, Ji M, Zhang F, et al. Effect of interconnection between cervical vagus trunk, epicardial fat pad on sinus node function, and atrial fibrillation. Pacing Clin Electrophysiol 2014;37:356–363. [5] Carnevali L, Graiani G, Rossi S, Al Banchaabouchi M, Macchi E, Quaini F, et al. Signs of cardiac autonomic imbalance and proarrhythmic remodeling in FTO deficient mice. PLoS One 2014;9:e95499. http://dx.doi.org/10.1371/ journal.pone.0095499. [6] Balcioglu AS, Cicek D, Akinci S, Eldem HO, Bal UA, Okyay K, et al. Arrhythmogenic evidence for epicardial adipose tissue: heart rate variability and turbulence are influenced by epicardial fat thickness. Pacing Clin Electrophysiol 2015;38:99–106.

The electrocardiogram showed 1 mm ST segment elevation in leads DII, DIII, aVF derivations and also complete AV block. His general condition and hemodynamic parameters were suddenly deteriorated. His blood pressure and heart rate dropped to 60/40 mmHg and 40/min respectively. Isotonic solution infusion started 1000 cc/hour and Atropin 1 mg initiated intravenously. After that his cardiac rhythm changed to the ventricular fibrillation. Following cardiac defibrillation, immediately coronary angiography performed.

We have read the report by Ramos et al. [(1)][1] in the Journal with great interest and excitement. The researchers have investigated patients from age 35 to 85 years with an ankle-brachial index (ABI) of 0.95 and without clinically recognized cardiovascular disease (CVD). They have categorized

We investigated the relationship between epicardial fat volume (EFV) measured by multislice computed tomography (MDCT) and long-term major adverse cardiac events (MACEs). Consecutive patients (n = 564) were enrolled in this retrospective study. Patients were divided into tertiles according to EFV. Patients were followed up for an average of 18 months. Patients in each tertile were similar in terms of gender and risk factors. Patients with greater EFV in the third group were more likely to be overweight ( P = .001) and older ( P = .001). High-density lipoprotein cholesterol levels were relatively lower in the third tertile (45 ± 9, 45 ± 11, and 43 ± 9 mg/dL, respectively; P = .018). The third group had a significantly higher rate of myocardial infarction (0.6%, 1.1%, and 3.7%, respectively; P = .043). The incidence of MACEs during the follow-up period was highest in the third group 15.9% (4.1%, 7.7%, and 15.9%, respectively; P = .001). Epicardial fat volume measured by MDCT was associated with increased long-term cardiovascular risk.

Endothelial dysfunction plays a major role in erectile dysfunction (ED). Uric acid (UA) is a marker of endothelial dysfunction. We hypothesized that increased UA levels may be associated with ED and aimed to investigate whether there is a relationship between, UA and ED in hypertensive patients.A total of 200 hypertensive patients who have a normal treadmill exercise test were divided into two groups based on the Sexual Health Inventory for Men (SHIM) test (21 defined as ED n = 110, and ≥ 21 defined as normal erectile function n = 90). The differences between the ED and normal erectile function groups were compared and determinants of ED were analyzed.The prevalence of ED was found to be 55.0%. Office blood pressure level was comparable between groups. UA levels were significantly increased in the ED group (6.20 ± 1.56 vs 5.44 ± 1.32, p = 0.01). In a regression model, age [odds ratio (95% confidence interval): 1.08 (1.04-1.14), p = 0.001], smoking [odds ratio: 2.33 (1.04-5.20), p = 0.04] and UA [odds ratio: 1.76 (1.28-2.41), p = 0.04] were independent determinants of ED. An UA level of5.2 mg/dl had 76.2% sensitivity, 43.7% specificity, 62.9% positive and 59.4% negative predictive value for determining ED.UA is an independent determinant of ED irrespective of blood pressure control and questioning erectile function for hypertensive patients with increased UA levels may be recommended.

Objective: The pre-procedural neutrophil to lymphocyte ratio (N/L) is associated with adverse outcomes among patients with coronary artery disease but its prognostic value in ST-segment elevation myocardial infarction (STEMI) has not been fully investigated. This study evaluated the relations between pre-procedural N/L ratio and the in-hospital and long-term outcomes in STEMI patients undergoing primary percutaneous coronary intervention (PCI)., Objective: The pre-procedural neutrophil to lymphocyte ratio (N/L) is associated with adverse outcomes among patients with coronary artery disease but its prognostic value in ST-segment elevation myocardial infarction (STEMI) has not been fully investigated. This study evaluated the relations between pre-procedural N/L ratio and the in-hospital and long-termoutcomes in STEMI patients undergoing primary percutaneous coronary intervention (PCI). Methods: A total of 682 STEMI patients presentedwithin the first 6 h of symptom onsetwere enrolled and stratified according to tertiles of N/L ratio based on the blood samples obtained in the emergency room upon admission. Results: The mean follow-up period was 43.3 months (1–131 months). In-hospital in-stent thrombosis, non-fatal myocardial infarction, and cardiovascular mortality increased as the N/L tertile ratio increased (p b0.001, pb0.001, p=0.003, respectively). Long-term in-stent thrombosis, non-fatalmyocardial infarction and cardiovascular mortality also increased as the N/L ratio increased (p b0.001, pb0.001, p=0.002, respectively). On multivariate analysis, N/L ratio remained an independent predictor for both in-hospital (OR 1.189, 95% CI 1.000 –1.339; pb0.001) and long-term major (OR 1.228, 95% CI 1.136 –1.328; pb0.001) adverse cardiac events. Conclusion: The N/L ratio was an independent predictor of both in-hospital and long-term adverse outcomes among STEMI patients undergoing primary PCI. Our findings suggest that this inexpensive, universally available hematological marker may be incorporated into the current established risk assessment model for STEMI.

Reoperative coronary artery bypass grafting (redo CABG)operation is associated with a high rate of mortality up to11.4%. It has been estimated that 10-20% of patients withhistory of coronary artery bypass grafting (CABG) operationneed redo CABG operation within 10 years. Due tohigh operation risk percutaneous coronary interventionshave emerged as the preferred treatment for the patientswith a history of CABG operation and presenting withacute coronary syndrome. Here, we reported percutaneouscoronary intervention in a patient needed redo CABGoperation. J Clin Exp Invest 2013; 4 (3): 380-382Key words: Acute coronary syndrome, redo CABG operation,percutaneous coronary intervention.

The usage of endovascular stent-graft in the treatment of abdominal aorta aneurysm has been increasing in the abdominal surgery. This paper presents the case of a patient with right iliac artery aneurysm who was treated with the application of endovascular stent-graft., Abdominal aort anevrizmasının tedavisinde endovasküler stent-greft uygulaması batın cerrahisine alternatif olarak giderek yaygınlaşmaktadır. Bu yazıda abdominal aorta ve sağ iliyak arter anevrizması olan bir hastanın endovasküler stent-greft yerleştirilerek yapılan tedavisi sunulmuştur.

to the editors: With great interest, we read the recent article by Mazzoccoli et al. ([3][1]), an association study between epicardial adipose tissue (EAT) thickness and cognitive impairment in the elderly, in the American Journal of Physiology-Heart and Circulatory Physiology . The authors very

We studied 92 patients to determine the relationship between the QRS treadmill score (QTS) and extent of coronary artery disease. The results were compared to those of ST segment deviation in a(+)QRS scorepopulation. A cut off point of5 mm was used for mild to moderate risk patients whereas a QTS of3 was considered high risk for the patients. 43% of the patients had high risk QTS and 57% mild to moderate QTS. A highly significant correlation was observed between the extent of coronary artery disease and the high risk group of patients, whereas nonsignificant changes were observed in the control group (p0.001). Finally, the results indicate that in patients with a (+) QTS score (5 mm), coronary artery disease was significant and accordingly extensive during coronary angiography. On the other hand, a (+) QRS score proved to be superior to ST deviation in predicting critical coronary stenoses in the same population (F ratio; 41 vs 24).

OP-037 Beta blockers and diuretics are frequently associated with erectile dysfunction (ED). However, the definitive mechanisms of ED secondary to these drugs are still unclear. Uric acid is a novel marker of atherosclerosis and endothelial dysfunction. Also, endothelial dysfunction plays a major

OP-089 Peri-aortic fat tissue is one of the visceral adipose deposits. Visceral adipose tissue is metabolically active and it is suggested that has proatherogenic effects induced by oxidative stress. Previous studies have shown that the relationship between peri-aortic adipose tissue and metabolic