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Background and Design: Isotretinoin is commonly used and effective treatment for acne. It has various side effects affecting lots of systems in the body. Nowadays, new cases are being reported regarding these side effects, and the number of studies related with long-term results is insufficient. In this study, the results and side effects of isotretinoin treatment were evaluated. Material and Method: One hundred and fifty patients with the diagnosis of moderate to severe acne were included in the study. The patients and their relatives were informed about the possible side effects. Isotretinoin treatment at a dose of 0.5-0.75 mg/kg/day was initiated and the cumulative dose of 120-150 mg/kg was achieved. The patients were scheduled for monthly follow-up visits. Results: Ninety-seven (64.6%) patients were women, 53 (35.4%) were men. All were aged between 16 and 47. The duration of disease varied from 1 to 20 years (mean: 4.46 years) and the treatment was applied for 3-9 months. The therapy was terminated due to depression (2 patients), extreme myalgia (1 patient), high level of triglycerides (2 patients), toxic hepatitis (3 patients). Recovery was achieved in 132 patients (88%) at the end of the treatment. The most commonly observed mucocutaneous side effects were cheilitis (100%), xerosis (56%), nose bleeding (34.8%), dermatitis (31%), and xerophthalmia (28%), beside the systemic side effects such as myalgia (45%), weakness (40%), and nervousness (36%). Side effects usually occurred within the early months and then diminished in course of time. The mostly seen laboratory abnormality was hypertrigliceridemia. Conclusion: Isotretinoin is the most commonly used treatment modality, which provides definitive benefits in many patients with acne. However, it should be used carefully, because it affects various systems. Although the drug has plenty of side effects, they are reversible and can be controlled. To raise awareness of the patients of these side effects will help to increase their tolerance. [ABSTRACT FROM AUTHOR]

Background and Design: Isotretinoin is commonly used and effective treatment for acne. It has various side effects affecting lots of systems in the body. Nowadays, new cases are being reported regarding these side effects, and the number of studies related with long-term results is insufficient. In this study, the results and side effects of isotretinoin treatment were evaluated. Material and Method: One hundred and fifty patients with the diagnosis of moderate to severe acne were included in the study. The patients and their relatives were informed about the possible side effects. Isotretinoin treatment at a dose of 0.5-0.75 mg/kg/day was initiated and the cumulative dose of 120-150 mg/kg was achieved. The patients were scheduled for monthly follow-up visits. Results: Ninety-seven (64.6%) patients were women, 53 (35.4%) were men. All were aged between 16 and 47. The duration of disease varied from 1 to 20 years (mean: 4.46 years) and the treatment was applied for 3-9 months. The therapy was terminated due to depression (2 patients), extreme myalgia (1 patient), high level of triglycerides (2 patients), toxic hepatitis (3 patients). Recovery was achieved in 132 patients (88%) at the end of the treatment. The most commonly observed mucocutaneous side effects were cheilitis (100%), xerosis (56%), nose bleeding (34.8%), dermatitis (31%), and xerophthalmia (28%), beside the systemic side effects such as myalgia (45%), weakness (40%), and nervousness (36%). Side effects usually occurred within the early months and then diminished in course of time. The mostly seen laboratory abnormality was hypertrigliceridemia. Conclusion: Isotretinoin is the most commonly used treatment modality, which provides definitive benefits in many patients with acne. However, it should be used carefully, because it affects various systems. Although the drug has plenty of side effects, they are reversible and can be controlled. To raise awareness of the patients of these side effects will help to increase their tolerance. [ABSTRACT FROM AUTHOR]

The article presents a case study of an 85-year-old woman who has the history of severe pruritus and crusted lesions on her face and was diagnosed with hepatitis C virus infection. Topics include the contagious crusted scabies was revealed after the dermatologic examination, the different diagnosis of crusted scabies and the effective treatments.

Copyright of Archives of the Turkish Dermatology & Venerology / Turkderm is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Archives of the Turkish Dermatology & Venerology / Turkderm is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Molluscum contagiosum (MC) is a viral disorder of the skin and mucous membranes, is characterized by domeshaped umbilicated, flesh-colored papules. In pediatric patients, the lesions are mostly seen on face, trunk and extremities. Genital MCV infection is often transmitted sexually and associated with concurrent sexually transmitted diseases. The presence of genital MC may be a sign of a child abuse. Two year- old female referred to our clinic with the lesion characterizing by dome-shaped, umblicated and flesh-colored papules in the anogenital area. Her family was queried for child abuse and there was no evidence of child abuse. We report this MC lesion because of its rare location. [ABSTRACT FROM AUTHOR]