232 results on '"Seow E."'
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2. Analysis of the interaction between pentraxins and Leishmania phosphoglycans
- Author
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Seow, E. S., Raynes, J. G., and Cliff, J. M.
- Abstract
CRP, a major acute phase protein, has also been shown to bind to Leishmania lipophosphoglycan (LPG) phosphorylated disaccharide repeats in a calcium-dependent manner. Similar structures have been observed in the promastigote secretory gel (PSG) components filamentous proteophosphoglycan (fPPG) and secreted acid phosphatase (ScAP). We investigate the ability of CRP, as well as related innate immune proteins, to bind to these Leishmania phosphoglycans, to determine their potential mechanisms as virulence factors of mammalian infection. CRP binding of PSG was shown to be calcium-dependent and on the same binding cleft involved in PC-binding. PSG from a range of Leishmania species (L.aethiopica, L.panamensis, L.donovani, L.infantum, L.mexicana, L.tropica, L.amazonensis, and L.major), as well as LPG derived from different L.mexicana promastigote stages, had the ability to bind to CRP and SAP with widely varying binding capacities. ScAP was determined to be the major CRP binding component in PSG. CRP-PSG binding was shown to be a high avidity and multimeric interaction. L.mexicana LPG stage-specific variations in size and pentraxin binding characteristics, as well as calcium-dependent binding of CRP and SAP, was demonstrated. CRP, but not SAP, binding to LPG was directed at the phosphorylated disaccharide repeats. A novel, orientation-dependent interaction of SAP binding to L.mexicana LPG was observed. LPG appeared to undergo a conformational change at a threshold of CRP binding (~2.5 μg/ml), affecting subsequent CRP binding affinity. Stage-variable LPG-PSG interaction dependent on CRP and calcium was demonstrated, with interaction being significantly greater in LPG derived from infectious stage promastigotes. PSG-CRP and LPG-CRP complex, but not LPG-SAP, was shown to be capable of binding C1q. PSG-CRP complex-mediated complement generation was shown to be primarily via the classical pathway (CP), with minor alternative pathway (AP) contribution.
- Published
- 2021
- Full Text
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3. Impact of curdlan on quality and sensory attributes of canned dodol made from glutinous rice flour.
- Author
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Yeoh, S.-Y., Pua, Y., Tan, T.-C., Seow, E.-K., and Azhar, M. E.
- Subjects
CURDLAN ,RICE flour ,PRODUCT attributes - Abstract
The effects of curdlan concentrations (0, 3, 5, and 7%) on the physical, textural, and sensorial properties of canned dodol (Candol) were investigated. The incorporation of curdlan in canned dodol significantly influenced several attributes of the product, including pH, total soluble solids (TSS), water activity (aw), moisture content, colour, texture, and microstructure. Curdlan decreased the pH level and increased the TSS level, while decreasing the moisture content and aw in certain samples. It also impacted the texture of dodol, with one sample (Candol-5) showing a texture similar to commercially available dodol. Additionally, microstructural differences were observed, with Candol-5 exhibiting the smallest pores and a more compact gel structure. Sensory panellists preferred the texture of Candol-5 over Candol-0, and its sensory rating was more similar to that of the commercial dodol, with no significant differences observed. In summary, curdlan could be a beneficial ingredient for improving the quality and acceptability of canned dodol, offering valuable insights for the development of innovative dodol products in the future. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
4. Price Discovery in Real Estate Auctions : The Story of Unsuccessful Attempts
- Author
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Ong, Seow E.
- Published
- 2006
5. Factors Influencing Auction Outcomes : Bidder Turnout, Auction Houses and Market Conditions
- Author
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Ong, Seow E., Lusht, Kenneth, and Mak, Chee Y.
- Published
- 2005
6. Residential Mortgage-Backed Securitization in Asia: The Singapore Experience
- Author
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Sing, Tien F. and Ong, Seow E.
- Published
- 2004
7. Large expert-curated database for benchmarking document similarity detection in biomedical literature search
- Author
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Brown, P, Zhou, Y, Tan, A, El-Esawi, M, Liehr, T, Blanck, O, Gladue, D, Almeida, G, Cernava, T, Sorzano, C, Yeung, A, Engel, M, Chandrasekaran, A, Muth, T, Staege, M, Daulatabad, S, Widera, D, Zhang, J, Meule, A, Honjo, K, Pourret, O, Yin, C, Zhang, Z, Cascella, M, Flegel, W, Goodyear, C, van Raaij, M, Bukowy-Bieryllo, Z, Campana, L, Kurniawan, N, Lalaouna, D, Huttner, F, Ammerman, B, Ehret, F, Cobine, P, Tan, E, Han, H, Xia, W, Mccrum, C, Dings, R, Marinello, F, Nilsson, H, Nixon, B, Voskarides, K, Yang, L, Costa, V, Bengtsson-Palme, J, Bradshaw, W, Grimm, D, Kumar, N, Martis, E, Prieto, D, Sabnis, S, Amer, S, Liew, A, Perco, P, Rahimi, F, Riva, G, Zhang, C, Devkota, H, Ogami, K, Basharat, Z, Fierz, W, Siebers, R, Tan, K, Boehme, K, Brenneisen, P, Brown, J, Dalrymple, B, Harvey, D, Ng, G, Werten, S, Bleackley, M, Dai, Z, Dhariwal, R, Gelfer, Y, Hartmann, M, Miotla, P, Tamaian, R, Govender, P, Gurney-Champion, O, Kauppila, J, Zhang, X, Echeverria, N, Subhash, S, Sallmon, H, Tofani, M, Bae, T, Bosch, O, Cuiv, P, Danchin, A, Diouf, B, Eerola, T, Evangelou, E, Filipp, F, Klump, H, Kurgan, L, Smith, S, Terrier, O, Tuttle, N, Ascher, D, Janga, S, Schulte, L, Becker, D, Browngardt, C, Bush, S, Gaullier, G, Ide, K, Meseko, C, Werner, G, Zaucha, J, Al-Farha, A, Greenwald, N, Popoola, S, Rahman, S, Xu, J, Yang, S, Hiroi, N, Alper, O, Baker, C, Bitzer, M, Chacko, G, Debrabant, B, Dixon, R, Forano, E, Gilliham, M, Kelly, S, Klempnauer, K, Lidbury, B, Lin, M, Lynch, I, Ma, W, Maibach, E, Mather, D, Nandakumar, K, Ohgami, R, Parchi, P, Tressoldi, P, Xue, Y, Armitage, C, Barraud, P, Chatzitheochari, S, Coelho, L, Diao, J, Doxey, A, Gobet, A, Hu, P, Kaiser, S, Mitchell, K, Salama, M, Shabalin, I, Song, H, Stevanovic, D, Yadollahpour, A, Zeng, E, Zinke, K, Alimba, C, Beyene, T, Cao, Z, Chan, S, Gatchell, M, Kleppe, A, Piotrowski, M, Torga, G, Woldesemayat, A, Cosacak, M, Haston, S, Ross, S, Williams, R, Wong, A, Abramowitz, M, Effiong, A, Lee, S, Abid, M, Agarabi, C, Alaux, C, Albrecht, D, Atkins, G, Beck, C, Bonvin, A, Bourke, E, Brand, T, Braun, R, Bull, J, Cardoso, P, Carter, D, Delahay, R, Ducommun, B, Duijf, P, Epp, T, Eskelinen, E, Fallah, M, Farber, D, Fernandez-Triana, J, Feyerabend, F, Florio, T, Friebe, M, Furuta, S, Gabrielsen, M, Gruber, J, Grybos, M, Han, Q, Heinrich, M, Helantera, H, Huber, M, Jeltsch, A, Jiang, F, Josse, C, Jurman, G, Kamiya, H, de Keersmaecker, K, Kristiansson, E, de Leeuw, F, Li, J, Liang, S, Lopez-Escamez, J, Lopez-Ruiz, F, Marchbank, K, Marschalek, R, Martin, C, Miele, A, Montagutelli, X, Morcillo, E, Nicoletti, R, Niehof, M, O'Toole, R, Ohtomo, T, Oster, H, Palma, J, Paterson, R, Peifer, M, Portilla, M, Portillo, M, Pritchard, A, Pusch, S, Raghava, G, Roberts, N, Ross, K, Schuele, B, Sergeant, K, Shen, J, Stella, A, Sukocheva, O, Uversky, V, Vanneste, S, Villet, M, Viveiros, M, Vorholt, J, Weinstock, C, Yamato, M, Zabetakis, I, Zhao, X, Ziegler, A, Aizat, W, Atlas, L, Bridges, K, Chakraborty, S, Deschodt, M, Domingues, H, Esfahlani, S, Falk, S, Guisado, J, Kane, N, Kueberuwa, G, Lau, C, Liang, D, Liu, E, Luu, A, Ma, C, Ma, L, Moyer, R, Norris, A, Panthee, S, Parsons, J, Peng, Y, Pinto, I, Reschke, C, Sillanpaa, E, Stewart, C, Uhle, F, Yang, H, Zhou, K, Zhu, S, Ashry, M, Bergsland, N, Berthold, M, Chen, C, Colella, V, Cuypers, M, Eskew, E, Fan, X, Gajda, M, Gonzalezlez-Prendes, R, Goodin, A, Graham, E, Groen, E, Gutierrez-Sacristan, A, Habes, M, Heffler, E, Higginbottom, D, Janzen, T, Jayaraman, J, Jibb, L, Jongen, S, Kinyanjui, T, Koleva-Kolarova, R, Li, Z, Liu, Y, Lund, B, Lussier, A, Mier, P, Moore, M, Nagler, K, Orme, M, Pearson, J, Prajapati, A, Saito, Y, Troder, S, Uchendu, F, Verloh, N, Voutchkova, D, Abu-Zaid, A, Bakkach, J, Baumert, P, Dono, M, Hanson, J, Herbelet, S, Hobbs, E, Kulkarni, A, Liu, S, Loft, N, Reddan, T, Senghore, T, Vindin, H, Xu, H, Bannon, R, Chen, B, Cheung, J, Cooper, J, Esnakula, A, Feghali, K, Ghelardi, E, Gnasso, A, Horbar, J, Lai, H, Ma, R, Pan, Z, Peres, M, Pranata, R, Seow, E, Sydes, M, Testoni, I, Westermair, A, Yang, Y, Afnan, M, Albiol, J, Albuquerque, L, Amir, S, Amiya, E, Amorim, R, An, Q, Andersen, S, Aplin, J, Argyropoulos, C, Asmann, Y, Assaeed, A, Atanasov, A, Atchison, D, Avery, S, Avillach, P, Baade, P, Backman, L, Badie, C, Baldi, A, Ball, E, Bardot, O, Barnett, A, Basner, M, Batra, J, Bazanova, O, Beale, A, Beddoe, T, Bell, M, Berezikov, E, Berners-Price, S, Bernhardt, P, Berry, E, Bessa, T, Billington, C, Birch, J, Blakely, R, Blaskovich, M, Blum, R, Boelaert, M, Bogdanos, D, Bosch, C, Bourgoin, T, Bouvard, D, Boykin, L, Bradley, G, Braun, D, Brownlie, J, Bruhl, A, Burt, A, Butler, L, Byrareddy, S, Byrne, H, Cabantous, S, Calatayud, S, Candal, E, Carlson, K, Casillas, S, Castelvetro, V, Caswell, P, Cavalli, G, Cerovsky, V, Chagoyen, M, Chen, D, Chen, H, Chen, J, Chen, Y, Cheng, C, Cheng, J, Chinapaw, M, Chinopoulos, C, Cho, W, Chong, L, Chowdhury, D, Chwalibog, A, Ciresi, A, Cockcroft, S, Conesa, A, Cook, P, Cooper, D, Coqueret, O, Corea, E, Costa, A, Costa, E, Coupland, C, Crawford, S, Cruz, A, Cui, H, Cui, Q, Culver, D, D'Angiulli, A, Dahms, T, Daigle, F, Dalgleish, R, Danielsen, H, Darras, S, Davidson, S, Day, D, Degirmenci, V, Demaison, L, Devriendt, K, Ding, J, Dogan, Y, Dong, X, Donner, C, Dressick, W, Drevon, C, Duan, H, Ducho, C, Dumaz, N, Dwarakanath, B, Ebell, M, Eisenhardt, S, Elkum, N, Engel, N, Erickson, T, Fairhead, M, Faville, M, Fejzo, M, Festa, F, Feteira, A, Flood-Page, P, Forsayeth, J, Fox, S, Franks, S, Frentiu, F, Frilander, M, Fu, X, Fujita, S, Galea, I, Galluzzi, L, Gani, F, Ganpule, A, Garcia-Alix, A, Gedye, K, Giordano, M, Giunta, C, Gleeson, P, Goarant, C, Gong, H, Gora, D, Gough, M, Goyal, R, Graham, K, Grande-Perez, A, Graves, P, Greidanus, H, Grice, D, Grunau, C, Gumulya, Y, Guo, Y, Gurevich, V, Gusev, O, Hacker, E, Hage, S, Hagen, G, Hahn, S, Haller, D, Hammerschmidt, S, Han, J, Han, R, Handfield, M, Hapuarachchi, H, Harder, T, Hardingham, J, Heck, M, Heers, M, Hew, K, Higuchi, Y, Hilaire, C, Hilton, R, Hodzic, E, Hone, A, Hongoh, Y, Hu, G, Huber, H, Hueso, L, Huirne, J, Hurt, L, Idborg, H, Ikeo, K, Ingley, E, Jakeman, P, Jensen, A, Jia, H, Jia, S, Jiang, J, Jiang, X, Jin, Y, Jo, D, Johnson, A, Johnston, M, Jonscher, K, Jorens, P, Jorgensen, J, Joubert, J, Jung, S, Junior, A, Kahan, T, Kamboj, S, Kang, Y, Karamanos, Y, Karp, N, Kelly, R, Kenna, R, Kennedy, J, Kersten, B, Khalaf, R, Khalid, J, Khatlani, T, Khider, T, Kijanka, G, King, S, Kluz, T, Knox, P, Kobayashi, T, Koch, K, Kohonen-Corish, M, Kong, X, Konkle-Parker, D, Korpela, K, Kostrikis, L, Kraiczy, P, Kratz, H, Krause, G, Krebsbach, P, Kristensen, S, Kumari, P, Kunimatsu, A, Kurdak, H, Kwon, Y, Lachat, C, Lagisz, M, Laky, B, Lammerding, J, Lange, M, Larrosa, M, Laslett, A, Laverman, G, Leclair, E, Lee, K, Lee, M, Li, G, Lieb, K, Lim, Y, Lindsey, M, Line, P, Liu, D, Liu, F, Liu, H, Lloyd, V, Lo, T, Locci, E, Loidl, J, Lorenzen, J, Lorkowski, S, Lovell, N, Lu, H, Lu, W, Lu, Z, Luengo, G, Lundh, L, Lysy, P, Mabb, A, Mack, H, Mackey, D, Mahdavi, S, Maher, P, Maher, T, Maity, S, Malgrange, B, Mamoulakis, C, Mangoni, A, Manke, T, Manstead, A, Mantalaris, A, Marsal, J, Marschall, H, Martin, F, Martinez-Raga, J, Martinez-Salas, E, Mathieu, D, Matsui, Y, Maza, E, Mccutcheon, J, Mckay, G, Mcmillan, B, Mcmillan, N, Meads, C, Medina, L, Merrick, B, Metzger, D, Meunier, F, Michaelis, M, Micheau, O, Mihara, H, Mintz, E, Mizukami, T, Moalic, Y, Mohapatra, D, Monteiro, A, Montes, M, Moran, J, Morozov, S, Mort, M, Murai, N, Murphy, D, Murphy, S, Murray, S, Naganawa, S, Nammi, S, Nasios, G, Natoli, R, Nguyen, F, Nicol, C, van Nieuwerburgh, F, Nilsen, E, Nobile, C, O'Mahony, M, Ohlsson, S, Olatunbosun, O, Olofsson, P, Ortiz, A, Ostrikov, K, Otto, S, Outeiro, T, Ouyang, S, Paganoni, S, Page, A, Palm, C, Paradies, Y, Parsons, M, Parsons, N, Pascal, P, Paul, E, Peckham, M, Pedemonte, N, Pellizzon, M, Petrelli, M, Pichugin, A, Pinto, C, Plevris, J, Pollesello, P, Polz, M, Ponti, G, Porcelli, P, Prince, M, Quinn, G, Quinn, T, Ramula, S, Rappsilber, J, Rehfeldt, F, Reiling, J, Remacle, C, Rezaei, M, Riddick, E, Ritter, U, Roach, N, Roberts, D, Robles, G, Rodrigues, T, Rodriguez, C, Roislien, J, Roobol, M, Rowe, A, Ruepp, A, van Ruitenbeek, J, Rust, P, Saad, S, Sack, G, Santos, M, Saudemont, A, Sava, G, Schrading, S, Schramm, A, Schreiber, M, Schuler, S, Schymkowitz, J, Sczyrba, A, Seib, K, Shi, H, Shimada, T, Shin, J, Shortt, C, Silveyra, P, Skinner, D, Small, I, Smeets, P, So, P, Solano, F, Sonenshine, D, Song, J, Southall, T, Speakman, J, Srinivasan, M, Stabile, L, Stasiak, A, Steadman, K, Stein, N, Stephens, A, Stewart, D, Stine, K, Storlazzi, C, Stoynova, N, Strzalka, W, Suarez, O, Sultana, T, Sumant, A, Summers, M, Sun, G, Tacon, P, Tanaka, K, Tang, H, Tanino, Y, Targett-Adams, P, Tayebi, M, Tayyem, R, Tebbe, C, Telfer, E, Tempel, W, Teodorczyk-Injeyan, J, Thijs, G, Thorne, S, Thrift, A, Tiffon, C, Tinnefeld, P, Tjahjono, D, Tolle, F, Toth, E, Del Tredici, A, Tsapas, A, Tsirigotis, K, Turak, A, Tzotzos, G, Udo, E, Utsumi, T, Vaidyanathan, S, Vaillant, M, Valsesia, A, Vandenbroucke, R, Veiga, F, Vendrell, M, Vesk, P, Vickers, P, Victor, V, Villemur, R, Vohl, M, Voolstra, C, Vuillemin, A, Wakelin, S, Waldron, L, Walsh, L, Wang, A, Wang, F, Wang, Y, Watanabe, Y, Weigert, A, Wen, J, Wham, C, White, E, Wiener, J, Wilharm, G, Wilkinson, S, Willmann, R, Wilson, C, Wirth, B, Wojan, T, Wolff, M, Wong, B, Wu, T, Wuerbel, H, Xiao, X, Xu, D, Xue, B, Yalcin, S, Yan, H, Yang, E, Yang, W, Ye, Y, Ye, Z, Yli-Kauhaluoma, J, Yoneyama, H, Yu, Y, Yuan, G, Yuh, C, Zaccolo, M, Zeng, C, Zevnik, B, Zhang, L, Zhang, Y, Zhao, Y, Zhou, M, Zuberbier, T, Aanei, C, Ahmad, R, Al-Lawama, M, Alanio, A, Allardyce, J, Alonso-Caneiro, D, Atack, J, Baier, D, Bansal, A, Benezeth, Y, Berbesque, C, Berrevoet, F, Biedermann, P, Bijleveld, E, Bittner, F, Blombach, F, van den Bos, W, Boudreau, S, Bramoweth, A, Braubach, O, Cai, Y, Campbell, M, Catry, T, Chen, X, Cheng, S, Chung, H, Chavez-Fumagalli, M, Conway, A, Costa, B, Cyr, N, Dean, L, Denzel, M, Dlamini, S, Dudley, K, Dufies, M, Ecke, T, Eckweiler, D, Eixarch, E, El-Adawy, H, Emmrich, J, Eustace, A, Falter-Wagner, C, Farhoudi, R, Fuss, J, Gao, J, Gill, M, Gloyn, L, Goggs, R, Govinden, U, Greene, G, Greiff, V, Grundle, D, Gruneberg, P, Gumede, N, Haore, G, Harrison, P, Hoenner, X, Hojsgaard, D, Hori, H, Ikonomopoulou, M, Jeurissen, P, Johnson, D, Kabra, D, Kamagata, K, Karmakar, C, Kasian, O, Kaye, L, Khan, M, Kim, Y, Kish, J, Kobold, S, Kohanbash, G, Kohls, G, Kugler, J, Kumar, G, Lacy-Colson, J, Latif, A, Lauschke, V, Li, B, Lim, C, Liu, X, Lu, J, Lu, Q, Mahavadi, P, Marzocchi, U, Mcgarrigle, C, van Meerten, T, Min, R, Moal, I, Molari, M, Molleman, L, Mondal, S, van de Mortel, T, Moss, W, Moultos, O, Mukherjee, M, Nakayama, K, Narayan, E, Navaratnarajah, Neumann, P, Nie, J, Nie, Y, Niemeyer, F, Nolan, F, Nwaiwu, O, Oldenmenger, W, Olumayede, E, Ou, J, Pallebage-Gamarallage, M, Pearce, S, Pelkonen, T, Pelleri, M, Pereira, J, Pheko, M, Pinto, K, Piovesan, A, Pluess, M, Podolsky, I, Prescott, J, Qi, D, Qi, X, Raikou, V, Ranft, A, Rhodes, J, Rotge, J, Saggar, M, Schuon, R, Shahid, S, Shalchyan, V, Shirvalkar, P, Shiryayev, O, Singh, J, Smout, M, Soares, A, Song, C, Srivastava, K, Srivastava, R, Sun, J, Szabo, A, Szymanski, W, Tai, C, Takeuchi, H, Tanadini-Lang, S, Tang, F, Tao, W, Theron, G, Tian, C, Tian, Y, Tuttle, L, Valenti, A, Verlot, P, Walker, M, Wang, J, Welter, D, Winslade, M, Wu, D, Wu, Y, Xiao, H, Xu, B, Xu, Z, Yang, D, Yang, M, Yankilevich, P, You, Y, Yu, C, Zhan, J, Zhang, G, Zhang, K, Zhang, T, Zhao, G, Zhao, J, Zhou, X, Zhu, Z, Ajani, P, Anazodo, U, Bagloee, S, Bail, K, Bar, I, Bathelt, J, Benkeser, D, Bernier, M, Blanchard, A, Boakye, D, Bonatsos, V, Boon, M, Bouboulis, G, Bromfield, E, Bul, K, Burton, K, Butkowski, E, Carroll, G, Chao, F, Charrier, E, Chenguang, Choi, J, Christoffersen, T, Comel, J, Cosse, C, Cui, Y, van Dessel, P, Dhaval, Diodato, D, Duffey, M, Dutt, A, Egea, L, El-Said, M, Faye, M, Fernandez-Fernandez, B, Foley, K, Founou, L, Fu, F, Gadelkareem, R, Galimov, E, Garip, G, Gemmill, A, Gouil, Q, Grey, J, Gridneva, Z, Grothe, M, Grebert, T, Guerrero, F, Guignard, L, Haenssgen, M, Hasler, D, Holgate, J, Huang, A, Hulse-Kemp, A, Jean-Quartier, C, Jeon, S, Jia, Y, Jutzeler, C, Kalatzis, P, Karim, M, Karsay, K, Keitel, A, Kempe, A, Keown, J, Khoo, C, Khwaja, N, Kievit, R, Kosanic, S, Koutoukidis, D, Kramer, P, Kumar, D, Kirag, N, Lanza, G, Le, T, Leem, J, Leightley, D, Leite, A, Lercher, L, Li, Y, Lim, R, Lima, L, Lin, L, Ling, T, Liu, Z, Lu, Y, Lum, F, Luo, H, Machhi, J, Macleod, A, Macwan, I, Madala, H, Madani, N, de Maio, N, Makowiecki, K, Mallinson, D, Margelyte, R, Maria, C, Markonis, Y, Marsili, L, Mavoa, S, Mcwilliams, L, Megersa, M, Souto-Maior, C, Menichetti, J, Mercieca-Bebber, R, Miller, J, Minde, D, Minges, A, Mishra, E, Mishra, V, Moores, C, Morrice, N, Moskalensky, A, Navarin, N, Negera, E, Nolet, P, Nordberg, A, Norden, R, Nowicki, J, Olova, N, 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- Abstract
Document recommendation systems for locating relevant literature have mostly relied on methods developed a decade ago. This is largely due to the lack of a large offline gold-standard benchmark of relevant documents that cover a variety of research fields such that newly developed literature search techniques can be compared, improved and translated into practice. To overcome this bottleneck, we have established the RElevant LIterature SearcH consortium consisting of more than 1500 scientists from 84 countries, who have collectively annotated the relevance of over 180 000 PubMed-listed articles with regard to their respective seed (input) article/s. The majority of annotations were contributed by highly experienced, original authors of the seed articles. The collected data cover 76% of all unique PubMed Medical Subject Headings descriptors. No systematic biases were observed across different experience levels, research fields or time spent on annotations. More importantly, annotations of the same document pairs contributed by different scientists were highly concordant. We further show that the three representative baseline methods used to generate recommended articles for evaluation (Okapi Best Matching 25, Term Frequency-Inverse Document Frequency and PubMed Related Articles) had similar overall performances. Additionally, we found that these methods each tend to produce distinct collections of recommended articles, suggesting that a hybrid method may be required to completely capture all relevant articles. The established database server located at https://relishdb.ict.griffith.edu.au is freely available for the downloading of annotation data and the blind testing of new methods. We expect that this benchmark will be useful for stimulating the development of new powerful techniques for title and title/abstract-based search engines for relevant articles in biomedical science.
- Published
- 2019
8. Prepayment Risk of Public Housing Mortgages
- Author
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Lee, Nai J. and Ong, Seow E.
- Published
- 2003
9. Singapore Advanced Cardiac Life Support Guidelines 2021
- Author
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Ching, CK, primary, Leong, BSH, additional, Nair, P, additional, Chan, KC, additional, Seow, E, additional, Lee, F, additional, Heng, K, additional, Sewa, DW, additional, Lim, TW, additional, Chong, DTT, additional, Yeo, KK, additional, Fong, WK, additional, Anantharaman, V, additional, and Lim, SH, additional
- Published
- 2021
- Full Text
- View/download PDF
10. Marital Status and Positive Mental Health of Psychiatric Outpatients
- Author
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Siva Kumar, F. D., Vaingankar, J. A., Sambasivam, R., Abdin, E., Jeyagurunathan, A., Seow, E., Louisa Picco, Chong, S. A., and Subramaniam, M.
- Subjects
Adult ,Male ,Singapore ,Marital Status ,Mental Disorders ,General Medicine ,Middle Aged ,Young Adult ,Mental Health ,Surveys and Questionnaires ,Outpatients ,Humans ,Female ,Aged - Published
- 2020
11. Experience of a screening centre for influenza A/H1N1: the first 50 days
- Author
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Chan, W L, Goh, H K, Vasu, A, Lim, B L, and Seow, E
- Published
- 2011
- Full Text
- View/download PDF
12. Predictors of frequent attenders of emergency department at an acute general hospital in Singapore
- Author
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Paul, P, Heng, B H, Seow, E, Molina, J, and Tay, S Y
- Published
- 2010
- Full Text
- View/download PDF
13. Patient satisfaction in an observation unit: the Consumer Assessment of Health Providers and Systems Hospital Survey
- Author
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Ng, C W L, Lim, G H, McMaster, F, Molina, J, Seow, E, and Heng, B H
- Published
- 2009
- Full Text
- View/download PDF
14. Large expert-curated database for benchmarking document similarity detection in biomedical literature search
- Author
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Zaritsky, A. Zhang, Y. Zhao, H. Zuckerman, H. Lyu, R. Pullan, W. RELISH Consortium
- Abstract
Document recommendation systems for locating relevant literature have mostly relied on methods developed a decade ago. This is largely due to the lack of a large offline gold-standard benchmark of relevant documents that cover a variety of research fields such that newly developed literature search techniques can be compared, improved and translated into practice. To overcome this bottleneck, we have established the RElevant LIterature SearcH consortium consisting of more than 1500 scientists from 84 countries, who have collectively annotated the relevance of over 180 000 PubMed-listed articles with regard to their respective seed (input) article/s. The majority of annotations were contributed by highly experienced, original authors of the seed articles. The collected data cover 76% of all unique PubMed Medical Subject Headings descriptors. No systematic biases were observed across different experience levels, research fields or time spent on annotations. More importantly, annotations of the same document pairs contributed by different scientists were highly concordant. We further show that the three representative baseline methods used to generate recommended articles for evaluation (Okapi Best Matching 25, Term Frequency-Inverse Document Frequency and PubMed Related Articles) had similar overall performances. Additionally, we found that these methods each tend to produce distinct collections of recommended articles, suggesting that a hybrid method may be required to completely capture all relevant articles. The established database server located at https://relishdb.ict.griffith.edu.au is freely available for the downloading of annotation data and the blind testing of new methods. We expect that this benchmark will be useful for stimulating the development of new powerful techniques for title and title/abstract-based search engines for relevant articles in biomedical science. © The Author(s) 2019. Published by Oxford University Press.
- Published
- 2019
15. Large expert-curated database for benchmarking document similarity detection in biomedical literature search
- Author
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H., Vendrell, M., Vesk, P. A., Vickers, P., Victor, V. M., Villemur, R., Vohl, M. -C., Voolstra, C. R., Vuillemin, A., Wakelin, S., Waldron, L., Walsh, L. J., Wang, A. Y., Wang, F., Wang, Y., Watanabe, Y., Weigert, A., Wen, J. -C., Wham, C., White, E. P., Wiener, J., Wilharm, G., Wilkinson, S., Willmann, R., Wilson, C., Wirth, B., Wojan, T. R., Wolff, M., Wong, B. M., Wu, T. -W., Wuerbel, H., Xiao, X., Xu, D., Xu, J. W., Xue, B., Yalcin, S., Yan, H., Yang, E. -C., Yang, S., Yang, W., Ye, Y., Ye, Z. -Q., Yli-Kauhaluoma, J., Yoneyama, H., Yu, Y., Yuan, G. -C., Yuh, C. -H., Zaccolo, M., Zeng, C., Zevnik, B., Zhang, L., Zhang, Y., Zhang, Z. -Y., Zhao, Y., Zhou, M., Zuberbier, T., Aanei, C. M., Ahmad, R., Al-Lawama, M., Alanio, A., Allardyce, J., Alonso-Caneiro, D., Atack, J. M., Baier, D., Bansal, A., Benezeth, Y., Berbesque, C., Berrevoet, F., Biedermann, P. H. W., Bijleveld, E., Bittner, F., Blombach, F., van den Bos, W., Boudreau, S. A., Bramoweth, A. 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Y., Huang, A., Hulse-Kemp, A. M., Jean-Quartier, C., Jeon, S. -M., Jia, Y., Jutzeler, C., Kalatzis, P., Karim, M., Karsay, K., Keitel, A., Kempe, A., Keown, J. R., Khoo, C. M., Khwaja, N., Kievit, R. A., Kosanic, S., Koutoukidis, D. A., Kramer, P., Kumar, D., Kirag, N., Lanza, G., Le, T. D., Leem, J. W., Leightley, D., Leite, A., Lercher, L., Li, Y., Lim, R., Lima, L. R. A., Lin, L., Ling, T., Liu, Y., Liu, Z., Lu, Y., Lum, F. M., Luo, H., Machhi, J., Macleod, A., Macwan, I., Madala, H. R., Madani, N., de Maio, N., Makowiecki, K., Mallinson, D. J., Margelyte, R., Maria, C., Markonis, Y., Marsili, L., Mavoa, S., Mcwilliams, L., Megersa, M., Souto-Maior, C., Menichetti, J., Mercieca-Bebber, R., Miller, J. J., Minde, D. -P. M., Minges, A., Mishra, E., Mishra, V. R., Moores, C., Morrice, N., Moskalensky, A. E., Navarin, N., Negera, E., Nolet, P., Nordberg, A., Norden, R., Nowicki, J. P., Olova, N., Olszewski, P., Onzima, R., Pan, C. -L., Park, C., Park, D. I., Park, S., Patil, C. D., Pedro, S. A., Perry, S. R., Peter, J., Peterson, B. M., Pezzuolo, A., Pozdnyakov, I., Qian, S., Qin, L., Rafe, A., Raote, I., Raza, A., Rebl, H., Refai, O., Regan, T., Richa, T., Richardson, M. F., Robinson, K. R., Rossoni, L., Rouet, R., Safaei, S., Schneeberger, P. H. H., Schwotzer, D., Sebastian, A., Selinski, J., Seltmann, S., Sha, F., Shalev, N., Shang, J. -L., Singer, J., Singh, M., Smith, T., Solomon-Moore, E., Song, L., Soraggi, S., Stanley, R., Steckhan, N., Strobl, F., Subissi, L., Supriyanto, I., Surve, C. R., Suzuki, T., Syme, C., Sorelius, K., Tang, Y., Tantawy, M., Tennakoon, S., Teseo, S., Toelzer, C., Tomov, N., Tovar, M., Tran, L., Tripathi, S., Tuladhar, A. M., Ukubuiwe, A. C., Ung, C. O. L., Valgepea, K., Vatanparast, H., Vidal, A., Wang, Q., Watari, R., Webster, R., Wei, J., Wibowo, D., Wingenbach, T. S. H., Xavier, R. M., Xiao, S., Xiong, P., Xu, S., Yao, R., Yao, W., Yin, Q., Zaitsu, M., Zeineb, Z., Zhan, X. -Y., Zhang, R., Zhang, W., Zheng, S., Zhou, B., Ahmad, H., Akinwumi, S. A., Albery, G. F., Alhowimel, A., Ali, J., Alshehri, M., Alsuhaibani, M., Anikin, A., Azubuike, S. O., Bach-Mortensen, A., Baltiansky, L., Bartas, M., Belachew, K. Y., Bhardwaj, V., Binder, K., Bland, N. S., Boah, M., Bullen, B., Calabro', Giovanna Elisa, Callahan, T. J., Cao, B., Chalmers, K., Chang, W., Che, Z., Chen, A. T. Y., Chen, Z., Choi, Y., Chowdhury, M. A. K., Christensen, M. R., Cooke, R. S. C., Cottini, M., Covington, N. V., Cunningham, C., Delarocque, J., Devos, L., Dhar, A. R., Ding, K. -F., Dong, K., Dong, Z., Dreyer, N., Ekstrand, C., Fardet, T., Feleke, B. E., Feurer, T., Freitas, A., Gao, T., Gebremedhin, Giganti, F., Grabowski, P., Guerra-Mora, J. R., Guo, C., Guo, X., Gupta, H., He, S., Heijne, M., Heinemann, S., Hogrebe, A., Huang, Z., Iskander-Rizk, S., Iyer, L. M., Jahan, Y., James, A. S., Joel, E., Joffroy, B., Jegousse, C., Kambondo, G., Karnati, P., Kaya, C., Ke, A., Kelly, D., Kickert, R., Kidibule, P. E., Kieselmann, J. P., Kim, H. J., Kitazawa, T., Lamberts, A., Liang, H., Linn, S. N., Litfin, T., Liusuo, W., Lygirou, V., Mahato, A. K., Mai, Z. -M., Major, R. W., Mali, S., Mallis, P., Mao, W., Marvin-Dowle, K., Mason, L. D., Merideth, B., Merino-Plaza, M. J., Merlaen, B., Messina, R., Mishra, A. K., Muhammad, J., Musinguzi, C., Nanou, A., Naqash, A., Nguyen, J. T., Nguyen, T. T. H., Ni, D., Nida, Notcovich, S., Ohst, B., Ollivier, Q. R., Osses, D. F., Peng, X., Plantinga, A., Pulia, M., Rafiq, M., Raman, A., Raucher-Chene, Rawski, R., Ray, A., Razak, L. A., Rudolf, K., Rusch, P., Sadoine, M. L., Schmidt, A., Schurr, R., Searles, S., Sharma, S., Sheehan, B., Shi, C., Shohayeb, B., Sommerlad, A., Strehlow, J., Sun, X., Sundar, R., Taherzadeh, G., Tahir, N. D. M., Tang, J., Testa, J., Tian, Z., Tingting, Q., Verheijen, G. P., Vickstrom, C., Wang, T., Wang, X., Wang, Z., Wei, P., Wilson, A., Wyart, Yassine, A. -A., Yousefzadeh, A., Zare, A., Zeng, Z., Zhang, H., Zhou, J., Zhu, D., Adamo, V., Adeyemo, A. A., Aggelidou, M., Al-Owaifeer, A. M., Al-Riyami, A. Z., Alzghari, S. K., Andersen, V., Angus, K., Asaduzzaman, M., Asady, H., Ato, D., Bai, X., Baines, R. L., Ballantyne, M., Ban, B., Beck, J., Ben-Nafa, W., Black, E., Blancher, A., Blankstein, R., Bodagh, N., Borges, P., Brooks, A., Brox-Ponce, J., Brunetti, A., Canham, C. D., Carninci, P., Carvajal, R., Chang, S. C., Chao, J., Chatterjee, P., Chen, L., Chhatriwalla, A. K., Chikowe, I., Chuang, T. -J., Collevatti, R. G., Cornejo, D. A. V., Cuenda, A., Dao, M., Dauga, D., Deng, Z., Devkota, K., Doan, L. V., Elewa, Y. H. A., Fan, D., Faruk, M., Feifei, S., Ferguson, T. S., Fleres, F., Foster, E. J., Foster, S., Furer, T., Gao, Y., Garcia-Rivera, E. J., Gazdar, A., George, R. B., Ghosh, S., Gianchecchi, E., Gleason, J. M., Hackshaw, A., Hall, A., Hall, R., Harper, P., Hogg, W. E., Huang, G., Hunter, K. E., Ijzerman, A. P., Jesus, C., Jian, G., Lewis, J. S., Kanj, S. S., Kaur, H., Kheir, F., Kichatova, V. S., Kiyani, M., Klein, R., Kovesi, T., Kraschnewski, J. L., Kumar, A. P., Labutin, D., Lazo-Langner, A., Leclercq, G., Li, M., Li, Q., Li, T., Liao, W. -T., Liao, Z. -Y., Lin, J., Lizer, J., Lobreglio, G., Lowies, C., Lu, C., Majeed, H., Martin, A., Martinez-Sobrido, L., Meresh, E., Middelveen, M., Mohebbi, A., Mota, J., Mozaheb, Z., Muyaya, L., Nandhakumar, A., Ng, S. H. X., Obeidat, M., Oh, D. -H., Owais, M., Pace-Asciak, P., Panwar, A., Patterson, C., Penagos-Tabaree, F., Pianosi, P. T., Pinzi, V., Pridans, C., Psaroulaki, A., Pujala, R. K., Pulido-Arjona, L., Qi, P. -F., Rahman, P., Rai, N. K., Rassaf, T., Refardt, J., Ricciardi, Walter, Riess, O., Rovas, A., Sacks, F. M., Saleh, S., Sampson, C., Schmutz, A., Sepanski, R., Sharma, N., Spearman, P., Subramaniapillai, M., Swali, R., Tan, C. M., Tellechea, J. I., Thomas, L. -M., Tong, X., Vavvas, D. G., Veys, R., Vitriol, V., Wang, H. -D., Waugh, J., Webb, S. A., Williams, B. A., Workman, A. D., Xiang, T., Xie, L. -X., Xu, T., Yang, C., Yoon, J. G., Yuan, C. M., Zaritsky, A., Zhao, H., Zuckerman, H., Lyu, R., Pullan, W., Calabro G. E. (ORCID:0000-0003-0259-3797), and Ricciardi W. (ORCID:0000-0002-5655-688X)
- Abstract
Document recommendation systems for locating relevant literature have mostly relied on methods developed a decade ago. This is largely due to the lack of a large offline gold-standard benchmark of relevant documents that cover a variety of research fields such that newly developed literature search techniques can be compared, improved and translated into practice. To overcome this bottleneck, we have established the RElevant LIterature SearcH consortium consisting of more than 1500 scientists from 84 countries, who have collectively annotated the relevance of over 180 000 PubMed-listed articles with regard to their respective seed (input) article/s. The majority of annotations were contributed by highly experienced, original authors of the seed articles. The collected data cover 76% of all unique PubMed Medical Subject Headings descriptors. No systematic biases were observed across different experience levels, research fields or time spent on annotations. More importantly, annotations of the same document pairs contributed by different scientists were highly concordant. We further show that the three representative baseline methods used to generate recommended articles for evaluation (Okapi Best Matching 25, Term Frequency-Inverse Document Frequency and PubMed Related Articles) had similar overall performances. Additionally, we found that these methods each tend to produce distinct collections of recommended articles, suggesting that a hybrid method may be required to completely capture all relevant articles. The established database server located at https://relishdb.ict.griffith.edu.au is freely available for the downloading of annotation data and the blind testing of new methods. We expect that this benchmark will be useful for stimulating the development of new powerful techniques for title and title/abstract-based search engines for relevant articles in biomedical science.
- Published
- 2019
16. Pattern of injuries in helmeted motorcyclists in Singapore
- Author
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Tham, K-Y, Seow, E, and Lau, G
- Published
- 2004
17. Managing change in the emergency department: a personal view
- Author
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Seow, E
- Published
- 2004
18. SARS: experience from the emergency department, Tan Tock Seng Hospital, Singapore
- Author
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Seow, E
- Published
- 2003
19. Spontaneous hepatico-duodenal fistula post-iatrogenic bile duct injury
- Author
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PONNUDURAL, R, SEOW, E. L., SINGH, HARJIT, RAMAN, K., WONG, C. M., TAN, W. J., SACHITHANANDAN, S., TAN, S. S., SANKER, L., ABDULLAH, A., and MERICAN, I.
- Published
- 2003
20. Comparison of CT and endoscopic ultrasound in the preoperative evaluation of pancreatic lesions
- Author
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PONNUDURAI, R., SEOW, E. L., SINGH, HARJIT, RAMAN, K., WONG, C. M., TAN, W. J., SACHITHANANDAN, S., TAN, S. S., SANKER, L., ABDULLAH, A., and MERICAN, I.
- Published
- 2003
21. The pattern of ambulance arrivals in the emergency department of an acute care hospital in Singapore
- Author
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Seow, E, Wong, H P, and Phe, A
- Published
- 2001
22. Disability in Singapore’s Elderly Population
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Mahesh, M., Abdin, E., Vaingankar, J. A., Louisa Picco, Jeyagurunathan, A., Shafie, S. B., Pang, S., Sagayadevan, V., Seow, E., Chong, S. A., and Subramaniam, M.
- Subjects
General Medicine - Abstract
Introduction: Disability increases an individual’s dependence and negatively impacts their physical, mental, and social functioning. The current study aims to establish the prevalence and risk factors of disability in Singapore’s population. Materials and Methods: Data was extracted from the Well-being of the Singapore Elderly (WiSE) study. This cross-sectional study recruited participants aged 60 years and above (n = 2421) who were representative of Singapore’s multiethnic population. We used the World Health Organization Disability Assessment Schedule (WHODAS) 2.0 to assess the severity of disability in our sample while establishing its associations and correlations with cognitive levels, sociodemographic variables, and chronic illness. Results: Cognitive deficits, old age, female gender, Malay and Indian ethnicity, lack of education, retired or homemaker status, presence of chronic illness (specifically stroke, heart problems, depression, and dementia) were found to be significantly associated with disability in Singapore’s elderly population. As hypothesised, participants with deficits in cognition were more likely to indicate higher WHODAS scores. Conclusion: The findings highlighted specific factors associated with disability in this multiethnic population. The identification of these factors would lead the way to the development of appropriate interventions. Key words: Chronic illness, Cognitive decline, Functioning, Old age
- Published
- 2016
23. Authors’ reply: Comment on: Prevalence and correlates of diabetes mellitus and dyslipidaemia in a long-stay inpatient schizophrenia population in Singapore
- Author
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Shafie, S, primary, Lee, SP, additional, Ong, SBC, additional, Wang, P, additional, Seow, E, additional, Ong, HL, additional, Chong, SA, additional, and Subramaniam, M, additional
- Published
- 2019
- Full Text
- View/download PDF
24. Successful ageing in Singapore: prevalence and correlates from a national survey of older adults
- Author
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Subramaniam, M, primary, Abdin, E, additional, Vaingankar, JA, additional, Sambasivam, R, additional, Seow, E, additional, Picco, L, additional, Chua, HC, additional, Mahendran, R, additional, Ng, LL, additional, and Chong, SA, additional
- Published
- 2019
- Full Text
- View/download PDF
25. Prevalence of Depression among Older Adults-Results from the Well-being of the Singapore Elderly Study
- Author
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Subramaniam, M., Abdin, E., Sambasivam, R., Vaingankar, J. A., Louisa Picco, Pang, S., Seow, E., Chua, B. Y., Magadi, H., Mahendran, R., and Chong, S. A.
- Subjects
Aged, 80 and over ,Male ,China ,Depressive Disorder ,Singapore ,Depression ,Malaysia ,India ,Social Support ,General Medicine ,Comorbidity ,Personal Satisfaction ,Middle Aged ,White People ,Cross-Sectional Studies ,Asian People ,Chronic Disease ,Ethnicity ,Odds Ratio ,Prevalence ,Quality of Life ,Humans ,Female ,Aged - Abstract
Introduction: Depression is a significant public health issue across all sociodemographic groups and is identified as a common and serious mental health problem particularly among the older adult population. The aims of the current study were to determine the prevalence of depression and subsyndromal depression among older adults in Singapore. Materials and Methods: The Well-being of the Singapore Elderly (WiSE) study was a comprehensive single phase, cross-sectional survey. Stage 1 Geriatric Mental State-Automated Geriatric Examination for Computer Assisted Taxonomy (GMS-AGECAT) depression syndrome was used for this analysis. Association of depression and subsyndromal depression with sociodemographic characteristics, social support as well as comorbidity with chronic physical illnesses and quality of life was assessed. Results: The prevalence of GMS-AGECAT depression and subsyndromal depression was 3.7% and 13.4%, respectively. The odds of depression were significantly higher among those aged 75 to 84 (2.1) as compared to those aged 60 to 74 years and in those who had a history of depression diagnosis by a doctor (4.1). The odds of depression were higher among those of Indian and Malay ethnicities (5.2 and 3.2 times, respectively) as compared to those of Chinese ethnicity. Those with depression and subsyndromal depression were associated with more disability, poorer life satisfaction, and medical comorbidities. Conclusion: Our study suggests that the prevalence of depression seems to have decreased as compared to a decade ago wherein the prevalence of depression was estimated to be 5.5%. This positive trend can be ascribed to concerted efforts across various disciplines and sectors, which need to be continually strengthened, monitored and evaluated. Key words: Comorbidity, GMS-AGECAT, Social support, Subsyndromal depression
- Published
- 2016
26. Traumatic diaphragmatic injuries: a retrospective review of a 12-year experience at a tertiary trauma centre
- Author
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Lim, BL, primary, Teo, LT, additional, Chiu, MT, additional, Asinas-Tan, ML, additional, and Seow, E, additional
- Published
- 2017
- Full Text
- View/download PDF
27. Help-seeking for sleep problems among psychiatric outpatients
- Author
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Chang, S., primary, Seow, E., additional, Lau, Y.W., additional, Chong, S.A., additional, and Subramaniam, M., additional
- Published
- 2017
- Full Text
- View/download PDF
28. Residential Mortgage-Backed Securitization in Asia: The Singapore Experience
- Author
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Seow E. Ong and Tien F. Sing
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Financial contagion ,Loan ,Real estate investment trust ,Economics, Econometrics and Finance (miscellaneous) ,Financial crisis ,Economics ,Real estate bubble ,Business, Management and Accounting (miscellaneous) ,Financial system ,Securitization ,Liquidity risk ,Market liquidity - Abstract
Securitizing residential mortgages has been used effectively to manage mortgage related risks like interest rate risks, credit risks, funding risks and sector concentration risks by financial institutions in many Asian countries. However, in Singapore, development of the residential mortgage-backed securitization (RMBS) market has been slow, despite strong support from the government of Singapore via revising securitization guidelines and making changes to policies that are favorable for RMBS development. Currently, an excess supply of liquidity and a perceived loss in the long-term relationship with the existing mortgagors/clients are the two main barriers to banks in securitizing their residential mortgages. Introduction Real estate bubbles and excessive lending have been suggested as the contributing causes for the 1997 Asian Financial Crisis by both the International Monetary Fund (IMF) (Collyns and Senhadji, 2000) and academic authors (Quigley, 2001; and Krugman, 1988). The high exposure of commercial banks and finance companies to real estate related loans appears to be connected to the financial and currency market crises in these Asian countries in 1997. The rapid escalation of asset prices in the mid 1990s fuelled by a large influx of foreign capital was not sustainable. The price bubble burst in mid-1997. Non-performing loans of financial institutions reached a critical level following a sharp decline in asset prices. Financial institutions and banks started to call their loans following a rapid depreciation of the countries' currencies. The inability of the borrowing institutions to liquidate their long-term loan assets to meet bank calls of loan repayment seriously disrupted the financial stability of many East Asian countries in 1997. Thailand was the first country to crumble under the financial pressure and the attack on its weakening currency. The "financial contagion" spreads quickly to other countries including Korea, Indonesia and Malaysia. The IMF swiftly stepped in to rescue three of the most seriously affected economies in Asia, Thailand, Korea and Indonesia, via a slew of financial re-capitalization and institutional restructuring measures. The Malaysian government has, on the other hand, severed its link to free exchange rate markets by introducing selective exchange and capital controls on September 1, 1998, which pegged the currency at Ringgit $3.80 to $1.00 U.S. The overreliance of households and corporations on bank loans for real estate purchases was one of the key factors underpinning the real estate bubble in the Asian markets. Various measures have been advocated to strengthen bank lending and to restrict the banks' lending to the real estate markets. The creation of the Real Estate Investment Trust (REIT) vehicle, which is so prevalent in the United States and the Australian markets, has been one of the policy recommendations, which is intended to provide an alternative source of financing for the real estate sector (Collyns and Senhadji, 2000). Securitizing mortgage loans has also been identified as a possible way to improve bank liquidity, and more importantly, to enforce greater discipline on bank underwriting and lending evaluation standards (Quigley, 2001). The Mortgage-Backed Securities (MBS) market was established in the U.S. with the objective of increasing liquidity and lowering the financing cost in the housing markets. It also serves to reduce financing institutions' exposure to various risks related to residential lending such as interest rate risk, credit risk, funding risk, liquidity risk and sectoral concentration risk. The Residential MBS (RMBS) history in the U.S. can be traced as far back to 1930s with the establishment of the Federal National Mortgage Association (FNMA) (Fannie Mae). Following the privatization of the FNMA in 1968, the Government National Mortgage Association (GNMA) (Ginnie Mae) was then set up under the Housing and Urban Development Act to serve mainly low and moderate income homebuyers. …
- Published
- 2004
29. Real Estate Appraisal and Transaction Price:An Empirical Evaluation of Alternative Theories
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Carl R. Gwin, Andrew C. Spieler, and Seow E. Ong
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Finance ,Actuarial science ,Transaction price ,business.industry ,Loan ,Economics ,Real estate appraisal ,business - Abstract
Mortgage appraisals are often required before a loan is approved. If information on the transaction price is available and lenders compensate appraisers, a principal-agent problem may arise. As a r...
- Published
- 2004
30. Positive Mental Health In Individuals With Mental Disorders
- Author
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Vaingankar, J., primary, Subramaniam, M., additional, Abdin, E., additional, Sambasivam, R., additional, Jeyagurunathan, A., additional, Seow, E., additional, Pang, S., additional, Picco, L., additional, and Chong, S.A., additional
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- 2016
- Full Text
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31. Female Trauma Patients in the Emergency Department: Should Their Injury Prevention Programs Be Different?
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Seow, E, Tham, KY, and Wong, HP
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Blunt trauma -- Demographic aspects ,Patients -- Injuries ,Health - Published
- 2000
32. Pattern of injuries in helmeted motorcyclists in Singapore
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Tham, K, Seow, E, and Lau, G
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Adult ,Male ,Singapore ,Thoracic Injuries ,Accidents, Traffic ,Middle Aged ,Prognosis ,Motorcycles ,Craniocerebral Trauma ,Humans ,Wounds and Injuries ,Original Article ,Female ,Head Protective Devices ,Hospital Mortality ,Emergency Service, Hospital - Abstract
Singapore has a mandatory helmet law for motorcyclists. This study aimed to determine the injuries sustained by helmeted motorcyclists presenting to the emergency Department (ED).Adult victims of motor vehicular incidents (MVI) who presented to an urban public hospital ED from 1 December 1998 to 31 May 1999 were interviewed. Chart reviews were done for those hospitalised. Data collected were demographic, nature of injury, ambulance care, ED and hospital care, outcome and final diagnoses.Motorcyclists formed 49.1% (1018) of all MVI victims, of whom 96.1% were men. The mean age was 32.5 years (SD 13.1), significantly younger (p0.0001) than the mean age of 36.4 years (SD 16.4) among other MVI victims. The proportions of motorcyclists and other MVI patients admitted to the hospital were not different. Among those admitted, significantly fewer (p = 0.001) motorcyclists (32.2%) sustained head injury compared with other MVI victims (46.8%) but among the motorcyclists with head injury, more than one third (34.2%) had severe head injury. The proportion of patients with thoracic injury was not different (p = 0.93) between motorcyclists (10.2%) and other MVI victims (9.9%). However, among those with thoracic injury, 79.2% of motorcyclists had severe thoracic injury, significantly more (p = 0.04) than 50% of other MVI patients. Wounds, fractures, and/or dislocations of the limbs (p0.001) were significantly more among motorcyclists compared with other MVI patients.Compared with other MVI victims, fewer helmeted motorcyclists sustained head injury. When head injury occurs in helmeted motorcyclists, it tends to be more severe. Motorcyclists remain vulnerable to extremity injury and to severe chest injury.
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- 2004
33. Quantification of rutin, quercitrin and quercetin in Cosmos caudatus Kunth by reverse phase high performance liquid chromatography.
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Sharifuldin, M. M. A., Ismail, Z., Aisha, A. F. A., Seow, E. K., and Beh, H. K.
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- 2016
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34. Discrimination between Cave and House-Farmed Edible Bird's Nest Based on Major Mineral Profiles.
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Seow, E. K., Ibrahim, B., Muhammad, S. A., Lee, L. H., Lalung, J., and Cheng, L. H.
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- *
EDIBLE birds' nests , *INSPECTION & review , *MINERALS , *PRINCIPAL components analysis , *HIERARCHICAL clustering (Cluster analysis) - Abstract
The high priced cave edible bird's nest (EBN) has attracted unscrupulous EBN producers to adulterate EBN with lower priced house-farmed EBN due to the fact that both are almost indistinguishable by visual inspection. In the present study, major mineral contents such as calcium, sodium, magnesium and potassium of both EBN types were analysed using inductively coupled plasma-optical emission spectrometry (ICP-OES). Three pattern recognition techniques namely hierarchical cluster analysis (HCA), principal component analysis (PCA) and linear discriminant analysis (LDA) were employed to determine the influence of harvesting origins on mineral profiles. With the use of HCA and PCA, EBN samples have successfully been grouped into two distinct clusters. From the PCA score plot, principal component 1 (49.53 %) and principal component 2 (41.11%) accounted for 90.64% of the total variability. In addition, LDA presented excellent performance in discriminating and predicting membership of the two EBN sample types with classification rate of 100%. [ABSTRACT FROM AUTHOR]
- Published
- 2016
35. (P2-68) Mental State of Healthcare Workers in a Designated H1N1 Screening Center
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Seow, E., primary, Hsin kai, G., additional, and Vasu, A., additional
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- 2011
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36. In vitro antibacterial, antioxidant, total phenolic contents and anti-HIV-1 reverse transcriptase activities of extracts of seven Phyllanthus sp
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Eldeen, I.M.S., primary, Seow, E-M., additional, Abdullah, R., additional, and Sulaiman, S.F., additional
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- 2011
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37. Experience of a screening centre for influenza A/H1N1: the first 50 days
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Chan, W. L., primary, Goh, H. K., additional, Vasu, A., additional, Lim, B. L., additional, and Seow, E., additional
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- 2010
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38. PHP58 FACTORS ASSOCIATED WITH REPEAT ATTENDANCE AT EMERGENCY DEPARTMENT (ED) OF A SECONDARY CARE HOSPITAL IN SINGAPORE
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Paul, P, primary, Heng, BH, additional, Tay, SY, additional, and Seow, E, additional
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- 2009
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39. 196: ST-Segment Elevation Myocardial Infarction: Is There a Sex Difference?
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Loh, S.S., primary, Lim, G.H., additional, Puah, E.J., additional, and Seow, E., additional
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- 2008
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40. A Profile of Male Domestic Violence Victims Presenting to an Emergency Department in Singapore
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Seow, E, primary and Foo, CL, additional
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- 2006
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41. Pain Management in the Emergency Department
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Lim, GH, primary, Wee, FC, additional, and Seow, E, additional
- Published
- 2006
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42. The Epidemiology and Mortality of Pelvic Fractures
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Phua, D., primary and Seow, E., additional
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- 2005
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43. Work-related Injury Sustained by Foreign Workers in Singapore
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Carangan, M, primary, Tham, KY, additional, and Seow, E, additional
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- 2004
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44. Female Trauma Patients in the Emergency Department: Should their Injury Prevention Programme be Different?
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Chan, KC, primary, Seow, E, additional, Lau, G, additional, Chan, SP, additional, and Tham, KY, additional
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- 2003
- Full Text
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45. Study on the Discrepancies between the Admitting Diagnoses from the Emergency Department and the Discharge Diagnoses
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Lim, GH, primary, Seow, E, additional, Koh, G, additional, Tan, D, additional, and Wong, HP, additional
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- 2002
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46. Pattern of injuries in helmeted motorcyclists in Singapore
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Tham, K-Y, primary, Seow, E, additional, and Wong, HP, additional
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- 1999
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47. 344 Medical Reponse in High-Rise Buildings
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Anantharaman, V, primary and Seow, E, additional
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- 1993
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48. 178 Organization of the Emergency Department in a Mass-Casualty Event When Little or No Warning is Given: Our Experience
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Seow, E, primary and Wong, H.P, additional
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- 1993
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49. Review of studies and guidelines on fasting and procedural sedation at the emergency department.
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Molina JAD, Lobo CA, Goh HK, Seow E, and Heng BH
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- 2010
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50. Epidemiology of travel-associated pandemic (H1N1) 2009 infection in 116 patients, Singapore.
- Author
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Mukherjee P, Lim PL, Chow A, Barkham T, Seow E, Win MK, Chua A, Leo YS, Cheng Chen MI, Mukherjee, Pratik, Lim, Poh Lian, Chow, Angela, Barkham, Timothy, Seow, Eillyne, Win, Mar Kyaw, Chua, Arlene, Leo, Yee Sin, and Cheng Chen, Mark I
- Abstract
In June 2009, during Singapore's pandemic influenza plan containment phase, pandemic (H1N1) 2009 was introduced into the country through imported cases. To understand how travel patterns affected the initial outbreak, we examined epidemiologic and travel data for the first 116 case-patients admitted to Tan Tock Seng Hospital, Singapore, with travel-associated infection. Sixty-one percent and 54% of patients, respectively, met US Centers for Disease Control and Prevention and World Health Organization temperature criteria for influenza-like illness. One fourth of the case-patients traveled after illness onset, and 15% became ill while traveling. Regions of exposure for imported infections changed rapidly; case-patients initially arrived from North America, followed by Australasia and Southeast Asia. Case-patients on longer flights were more likely to become ill before arrival; those with shorter flights tended to become ill after arrival. Thermal scanners detected fevers in 12% of the arriving case-patients, resulting in a shorter time to isolation. [ABSTRACT FROM AUTHOR]
- Published
- 2010
- Full Text
- View/download PDF
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