24 results on '"Sensintaffar, John L."'
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2. Fragment-Based Screen of SARS-CoV‑2 Papain-like Protease (PLpro).
3. Structure-Based Discovery of Potent, Orally Bioavailable Benzoxazepinone-Based WD Repeat Domain 5 Inhibitors
4. Structure-based discovery of potent WD repeat domain 5 inhibitors that demonstrate efficacy and safety in preclinical animal models
5. Discovery and biological characterization of potent myeloid cell leukemia‐1 inhibitors
6. Structure-based discovery of potent WD repeat domain 5 inhibitors that demonstrate efficacy and safety in preclinical animal models.
7. Discovery and Structure-Based Optimization of Potent and Selective WDR5 Inhibitors Containing a Dihydroisoquinolinone Bicyclic Core
8. Discovery and Structure-Based Optimization of Potent and Selective WD Repeat Domain 5 (WDR5) Inhibitors Containing a Dihydroisoquinolinone Bicyclic Core
9. Abstract 3987: Predicting MCL1 inhibitor sensitivity in large cell line panels using a gene expression signature
10. Discovery of Potent Myeloid Cell Leukemia-1 (Mcl-1) Inhibitors That Demonstrate in Vivo Activity in Mouse Xenograft Models of Human Cancer
11. Optimization of Potent and Selective Tricyclic Indole Diazepinone Myeloid Cell Leukemia-1 Inhibitors Using Structure-Based Design
12. Discovery and Biological Characterization of Potent Myeloid Cell Leukemia-1 (Mcl-1) Inhibitors
13. Discovery and Structure-Based Optimization of Potent and Selective WD Repeat Domain 5 (WDR5) Inhibitors Containing a Dihydroisoquinolinone Bicyclic Core
14. Discovery of a Myeloid Cell Leukemia 1 (Mcl-1) Inhibitor That Demonstrates Potent In VivoActivities in Mouse Models of Hematological and Solid Tumors
15. Discovery and biological characterization of potent myeloid cell leukemia‐1 inhibitors
16. Abstract 3551: Discovery of orally bioavailable novel Mcl-1 inhibitors that exhibit selective anti-proliferative activity in Mcl-1 sensitive cancer cell lines
17. Abstract 3727: Small molecule Mcl-1 inhibitors induce apoptosis and death in multiple cancer subtypesin vitro
18. Discovery of 2-Indole-acylsulfonamide Myeloid Cell Leukemia 1 (Mcl-1) Inhibitors Using Fragment-Based Methods
19. BIIB021, an orally available, fully synthetic small-molecule inhibitor of the heat shock protein Hsp90
20. Rationally Designed High-Affinity 2-Amino-6-halopurine Heat Shock Protein 90 Inhibitors That Exhibit Potent Antitumor Activity
21. 7‘-Substituted Benzothiazolothio- and Pyridinothiazolothio-Purines as Potent Heat Shock Protein 90 Inhibitors
22. Orally Active Purine-Based Inhibitors of the Heat Shock Protein 90
23. Fragment-Based Screen of SARS-CoV-2 Papain-like Protease (PL pro ).
24. Orally active purine-based inhibitors of the heat shock protein 90.
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