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1. The Effects of a STEM-Based Intervention on Middle School Students' Science Achievement and Learning Motivation

Author

Uzun, Salih and Sen, Nihat

Abstract

The goal of STEM education is to integrate the disciplines of science, technology, engineering, and mathematics in a way that facilitates holistic learning. Students are also supported in developing creative solutions to problems using the STEM approach. Other STEM fields are often linked through engineering and engineering design. Throughout this study, students participated in engineering design-oriented activities that connected STEM disciplines. This study aims to reveal the effect of a learning environment based on the STEM approach in science education on students' academic achievement and motivation. This study used a quasi-experimental, non-equivalent pretest-posttest control group design. Seventh-graders who attended a public middle school in the Aegean Region of Türkiye participated in the study. The research findings showed a significant difference in science achievement between the control group in the curriculum-based learning environment and the experimental group in the STEM-based learning environment. It was found, however, that motivation toward science was not significantly different. The results indicated that the STEM-based learning environment positively affected science achievement.

Published
2023

39. Serum uric acid, inflammation, and nondipping circadian pattern in essential hypertension

Author

Turak, Osman, Özcan, Fırat, Tok, Derya, İşleyen, Ahmet, Sökmen, Erdoğan, Taşoğlu, Irfan, Aydoğdu, Sinan, Sen, Nihat, McFann, Kim, Johnson, Richard J., and Kanbay, Mehmet

Subjects
Inflammation, Male, Analysis of Variance, Chi-Square Distribution, Blood Pressure Monitoring, Ambulatory, Middle Aged, Original Papers, Circadian Rhythm, Uric Acid, C-Reactive Protein, Logistic Models, Case-Control Studies, Hypertension, Humans, Female, Letters to the Editor, Biomarkers
Abstract

Uric acid (UA) is independently associated with the emergence of hypertension. Nocturnal nondipping pattern of hypertension is associated with a greater risk of cardiovascular, renal, and cerebrovascular complications than dippers. The aim of the present study was to evaluate the relationship between the circadian blood pressure rhythm and UA level in patients with newly diagnosed essential hypertension. The study included 112 essential hypertensive patients and 50 healthy controls. The hypertensive patients were divided into two groups according to the results of 24‐hour ambulatory blood pressure monitoring, including 60 dippers (35 men, 25 women; mean age, 52.6±15.8 years) and 52 nondippers (29 men, 23 women; mean age, 55.9±13.2 years). Nondippers had significantly higher serum UA levels than the dippers and controls (5.8±0.8, 5.1±0.9 and 4.2±0.9 mg/dL, respectively; P

Published
2013

41. Left ventricular functions in patients with cardiac syndrome X: a tissue Doppler study

Author

Cengel, Atiye, Yazici, Hueseyin Ugur, Poyraz, Fatih, Tavil, Yusuf, Hizal, Fatma, Turfan, Murat, Boyaci, Buelent, and Sen, Nihat

Subjects
cardiovascular system, circulatory and respiratory physiology
Abstract

Objective:The aim of the study was to compare diagnostic accuracy of tissue Doppler imaging (TDI) and conventional Doppler echocardiography in diagnosis of left ventricular diastolic dysfunction in patients with cardiac syndrome X.

Published
2009

42. Nebivolol therapy improves endothelial function and increases exercise tolerance in patients with cardiac syndrome X

Author

Sen, Nihat, Tavil, Yusuf, Erdamar, Huesamettin, Yazici, Hueseyin Ugur, Cakir, Erdinc, Bilgi, Cumhur, Erbil, Mehmet Kemal, Poyraz, Fatih, kaan okyay, Turfan, Murat, Cemri, Mustafa, and Akgul, Emin Ozgur

Abstract

Objective: We sought to determine whether nebivolol affects coronary endothelial function and exercise induced ischemia in patients with cardiac syndrome X (CSX).

Published
2009

49. Authors’ response to the comments on automated platelet analyses by Dr Beyan

Author

Akpinar, Ibrahim, primary, Sayin, Muhammet Rasit, additional, Gursoy, Yusuf Cemil, additional, Aktop, Ziyaeddin, additional, Karabag, Turgut, additional, Kucuk, Emrah, additional, Aydin, Mustafa, additional, Sen, Nihat, additional, Kiran, Sibel, additional, Buyukuysal, Mustafa Cagatay, additional, and Haznedaroglu, Ibrahim Celal, additional

Published
2014
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50. The relation of fragmented QRS with tissue Doppler derived parameters in patients with b-thalassaemia major

Author

Buyukkaya , Eyup, Karakas, Mehmet Fatih, Kurt, Mustafa, Bilen, Perihan, Yalcın, Fatih, Celik , Murat, Helvacı, Rami, Kaya, Hasan, Ertekin, Filiz, Sökmen, Erdogan, Sen, Nihat, Akcay, Adnan Burak, Buyukkaya , Eyup, Karakas, Mehmet Fatih, Kurt, Mustafa, Bilen, Perihan, Yalcın, Fatih, Celik , Murat, Helvacı, Rami, Kaya, Hasan, Ertekin, Filiz, Sökmen, Erdogan, Sen, Nihat, and Akcay, Adnan Burak

Abstract

Purpose: The most important complication encountered in patients with b-thalassaemia major is degenerative fibrosis developing as a result of iron accumulation in myocardial tissue. Dysfunction pursues this accumulation. Recently, presence of fragmented QRS (fQRS) in ECG has been regarded as a predictor of myocardial fibrosis. We aimed in our study to investigate the frequency with which fQRS develops in patients with b-thalassaemia major and to disclose the correlation between fQRS frequency and Doppler-derived indices. Methods: The patients with b-thalassaemia major (n=66; mean age: 23±6 years) and healthy controls (n=30; mean age: 23±4 years) were included. fQRS pattern was described as presence of RSR’ manifested as existence of additional R wave and notching in either R or S waves in ECG recordings. 2D, M-mode, conventional Doppler, tissue Doppler echocardiography parameters were assessed. Mean serum ferritin levels over past 5 years were also calculated. Results: When compared to those in control group, fQRS was more frequent in b-thalassaemia major group, indicating statistical significance (p = 0.001). While E/Em and ferritin level exhibited statistically significant increase in thalassaemia patients with fQRS (p < 0.05), the mean Em and Sm values were found to be significantly low (p < 0.05). Conclusions: fQRS was frequently observed in the patients with b-thalassaemia major, which was of statistical significance. Tissue Doppler-derived diastolic and systolic indices in thalassaemia cases with fQRS showed statistically significant impairment compared to those without fQRS. In conclusion, fQRS may represent a novel noninvasive marker for cardiac involvement in patients with b-thalassaemia major.

Published
2012

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