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2. MP74-11 COMPARISON OF PCA DETECTION RATES IN PATIENTS WHO UNDERWENT MRI/TRUS FUSION PROSTATE BIOPSY: ELASTIC VS RIGID SOFTWARE-BASED SYSTEMS

Author

Fanelli, Antonio, primary, Selvaggio, Oscar, additional, Milillo, Paola, additional, Ninivaggi, Antonella, additional, Finati, Marco, additional, Montrone, Luca, additional, Troiano, Francesco, additional, Guzzi, Francesco, additional, Falagario, Ugo Giovanni, additional, Bettocchi, Carlo, additional, Busetto, Gian Maria, additional, Cormio, Luigi, additional, and Carrieri, Giuseppe, additional

Published
2024
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3. Combined Use of Prostate-specific Antigen Density and Magnetic Resonance Imaging for Prostate Biopsy Decision Planning: A Retrospective Multi-institutional Study Using the Prostate Magnetic Resonance Imaging Outcome Database (PROMOD)

Author

Falagario, Ugo Giovanni, Jambor, Ivan, Lantz, Anna, Ettala, Otto, Stabile, Armando, Taimen, Pekka, Aronen, Hannu J., Knaapila, Juha, Perez, Ileana Montoya, Gandaglia, Giorgio, Fossati, Nicola, Martini, Alberto, Cucchiara, Vito, Picker, Wolfgang, Haug, Erik, Ratnani, Parita, Haines, Kenneth, Lewis, Sara, Sujit, Nair, Selvaggio, Oscar, Sanguedolce, Francesca, Macarini, Luca, Cormio, Luigi, Nordström, Tobias, Tewari, Ash, Briganti, Alberto, Boström, Peter J., and Carrieri, Giuseppe

Published
2021
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5. External Validation of the IMPROD-MRI Volumetric Model to Predict the Utility of Systematic Biopsies at the Time of Targeted Biopsy

Author

Ninivaggi, Antonella, primary, Guzzi, Francesco, additional, Degennaro, Alessio, additional, Ricapito, Anna, additional, Bettocchi, Carlo, additional, Busetto, Gian Maria, additional, Sanguedolce, Francesca, additional, Milillo, Paola, additional, Selvaggio, Oscar, additional, Cormio, Luigi, additional, Carrieri, Giuseppe, additional, and Falagario, Ugo Giovanni, additional

Published
2023
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6. Abiraterone Acetate for Treatment of Metastatic Castration-resistant Prostate Cancer in Chemotherapy-naive Patients: An Italian Analysis of Patients' Satisfaction

Author

Cindolo, Luca, Natoli, Clara, De Nunzio, Cosimo, De Tursi, Michele, Valeriani, Maurizio, Giacinti, Silvana, Micali, Salvatore, Rizzo, Mino, Bianchi, Giampaolo, Martorana, Eugenio, Scarcia, Marcello, Ludovico, Giuseppe Mario, Bove, Pierluigi, Laudisi, Anastasia, Selvaggio, Oscar, Carrieri, Giuseppe, Bada, Maida, Castellan, Pietro, Topazio, Luca, Boccasile, Stefano, Ditonno, Pasquale, Chiodini, Paolo, and Schips, Luigi

Published
2017
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9. Foggia Prostate Cancer Risk Calculator 2.0: A Novel Risk Calculator including MRI and Bladder Outlet Obstruction Parameters to Reduce Unnecessary Biopsies

Author

Falagario, Ugo Giovanni, primary, Busetto, Gian Maria, additional, Recchia, Marco, additional, Tocci, Edoardo, additional, Selvaggio, Oscar, additional, Ninivaggi, Antonella, additional, Milillo, Paola, additional, Macarini, Luca, additional, Sanguedolce, Francesca, additional, Mancini, Vito, additional, Annese, Pasquale, additional, Bettocchi, Carlo, additional, Carrieri, Giuseppe, additional, and Cormio, Luigi, additional

Published
2023
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10. Oncological outcomes of whole-gland cryoablation in patients with prostate cancer and high risk of lymph node invasion

Author

Finati, Marco, primary, Selvaggio, Oscar, additional, Falagario, UgoGiovanni, additional, Bruno, SalvatoreMariano, additional, Recchia, Marco, additional, Milillo, Paola, additional, Sanguedolce, Francesca, additional, Silecchia, Giovanni, additional, Macarini, Luca, additional, Cormio, Luigi, additional, and Carrieri, Giuseppe, additional

Published
2023
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11. Pros-IT CNR: an Italian prostate cancer monitoring project

Author

Noale, Marianna, Maggi, Stefania, Artibani, Walter, Bassi, Pier Francesco, Bertoni, Filippo, Bracarda, Sergio, Conti, Giario Natale, Corvò, Renzo, Gacci, Mauro, Graziotti, Pierpaolo, Magrini, Stefano Maria, Maurizi Enrici, Riccardo, Mirone, Vincenzo, Montironi, Rodolfo, Muto, Giovanni, Pecoraro, Stefano, Porreca, Angelo, Ricardi, Umberto, Tubaro, Andrea, Zagonel, Vittorina, Zattoni, Filiberto, Crepaldi, Gaetano, Crepaldi, Gaetano, Maggi, Stefania, Noale, Marianna, Porreca, Angelo, Artibani, Walter, Bassi, Pier Francesco, Bracarda, Sergio, Conti, Giario Natale, Corvò, Renzo, Graziotti, Pierpaolo, Maurizi Enrici, Riccardo, Mirone, Vincenzo, Montironi, Rodolfo, Bertoni, Filippo, Gacci, Mauro, Magrini, Stefano Maria, Muto, Giovanni, Pecoraro, Stefano, Ricardi, Umberto, Tubaro, Andrea, Zagonel, Vittorina, Zattoni, Filiberto, Alitto, Anna Rita, Ambrosi, Enrica, Antonelli, Alessandro, Aristei, Cynthia, Barbieri, Michele, Bardari, Franco, Bardoscia, Lilia, Barra, Salvina, Bartoncini, Sara, Basso, Umberto, Becherini, Carlotta, Bellavita, Rita, Bergamaschi, Franco, Berlingheri, Stefania, Berruti, Alfredo, Borghesi, Marco, Bortolus, Roberto, Borzillo, Valentina, Bosetti, Davide, Bove, Giuseppe, Bove, Pierluigi, Brausi, Maurizio, Bruni, Alessio, Bruno, Giorgio, Brunocilla, Eugenio, Buffoli, Alberto, Buglione, Michela, Buttigliero, Consuelo, Cacciamani, Giovanni, Caldiroli, Michela, Cardo, Giuseppe, Carmignani, Giorgio, Carrieri, Giuseppe, Castelli, Emanuele, Castrezzati, Elisabetta, Catalano, Gianpiero, Cattarino, Susanna, Catucci, Francesco, Cavallini Francolini, Dario, Ceccarini, Ofelia, Celia, Antonio, Chiancone, Francesco, Chini, Tommaso, Cianci, Claudia, Cisternino, Antonio, Collura, Devis, Corbella, Franco, Corinti, Matteo, Corsi, Paolo, Cortese, Fiorenza, Corti, Luigi, de Nunzio, Cosimo, Cristiano, Olga, D’Angelillo, Rolando, Da Pozzo, Luigi, D’agostino, Daniele, D’Andrea, David, Dandrea, Matteo, De Angelis, Michele, De Cobelli, Ottavio, De Concilio, Bernardino, De Lisa, Antonello, De Luca, Stefano, De Stefani, Agostina, Deantoni, Chiara Lucrezia, Degli Esposti, Claudio, Destito, Anna, Detti, Beatrice, Di Muzio, Nadia, Di Stasio, Andrea, Di Stefano, Calogero, Di Trapani, Danilo, Difino, Giuseppe, Falivene, Sara, Farullo, Giuseppe, Fedelini, Paolo, Ferrari, Ilaria, Ferrau, Francesco, Ferro, Matteo, Fodor, Andrei, Fontana, Francesco, Francesca, Francesco, Giulio, Francolini, Frata, Paolo, Frezza, Giovanni, Gabriele, Pietro, Galeandro, Maria, Garibaldi, Elisabetta, Gennari, Pietro, Gentilucci, Alessandro, Giacobbe, Alessandro, Giussani, Laura, Giusti, Giuseppe, Gontero, Paolo, Guarneri, Alessia, Guida, Cesare, Gurioli, Alberto, Huqi, Dorijan, Imbimbo, Ciro, Ingrosso, Gianluca, Iotti, Cinzia, Italia, Corrado, La Mattina, Pierdaniele, Lamanna, Enza, Lastrucci, Luciana, Lazzari, Grazia, Liberale, Fabiola, Liguori, Giovanni, Lisi, Roberto, Lohr, Frank, Lombardo, Riccardo, Lovisolo, Jon, Ludovico, Giuseppe Mario, Macchione, Nicola, Maggio, Francesca, Malizia, Michele, Manasse, Gianluca, Mandoliti, Giovanni, Mantini, Giovanna, Marafioti, Luigi, Marciello, Luisa, Marconi, Alberto Mario, Martillotta, Antonietta, Marzano, Salvino, Masciullo, Stefano, Maso, Gloria, Massenzo, Adele, Mazzeo, Ercole, Mearini, Luigi, Medoro, Serena, Molè, Rosa, Monesi, Giorgio, Montanari, Emanuele, Montefiore, Franco, Montesi, Giampaolo, Morgia, Giuseppe, Moro, Gregorio, Muscas, Giorgio, Musio, Daniela, Muto, Paolo, Muzzonigro, Giovanni, Napodano, Giorgio, Negro, Carlo Luigi Augusto, Nidini, Mattia, Ntreta, Maria, Orsatti, Marco, Palazzolo, Carmela, Palumbo, Isabella, Parisi, Alessandro, Parma, Paolo, Pavan, Nicola, Pericolini, Martina, Pinto, Francesco, Pistone, Antonio, Pizzuti, Valerio, Platania, Angelo, Polli, Caterina, Pomara, Giorgio, Ponti, Elisabetta, Porcaro, Antonio Benito, Porpiglia, Francesco, Pugliese, Dario, Pycha, Armin, Raguso, Giuseppe, Rampini, Andrea, Randone, Donato Franco, Roscigno, Marco, Ruggieri, Maria Paola, Ruoppo, Giuseppe, Sanseverino, Roberto, Santacaterina, Anna, Santarsieri, Michele, Santoni, Riccardo, Scagliarini, Sarah, Scagliotti, Giorgio Vittorio, Scanzi, Mauro, Scarcia, Marcello, Schiavina, Riccardo, Sciarra, Alessandro, Sciorio, Carmine, Scolaro, Tindaro, Scuzzarella, Salvatore, Selvaggio, Oscar, Serao, Armando, Serni, Sergio, Signor, Marco Andrea, Silvani, Mauro, Silvano, Giovanni, Silvestris, Franco, Simeone, Claudio, Simone, Valeria, Spagnoletti, Girolamo, Spinelli, Matteo Giulio, Squillace, Luigi, Tombolini, Vincenzo, Toninelli, Mariastella, Triggiani, Luca, Trinchieri, Alberto, Trodella, Luca Eolo, Trodella, Lucio, Trombetta, Carlo, Tronnolone, Lidia, Tucci, Marcello, Urzì, Daniele, Valdagni, Riccardo, Valeriani, Maurizio, Vanoli, Maurizio, Vitali, Elisabetta, Zaramella, Stefano, Zeccolini, Guglielmo, Zini, Giampaolo, and the Pros-IT CNR study group

Published
2017
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15. One-Day Prostate Cancer Diagnosis: Biparametric Magnetic Resonance Imaging and Digital Pathology by Fluorescence Confocal Microscopy

Author

Falagario, Ugo Giovanni, primary, Selvaggio, Oscar, additional, Sanguedolce, Francesca, additional, Milillo, Paola, additional, Sighinolfi, Maria Chiara, additional, Bruno, Salvatore Mariano, additional, Recchia, Marco, additional, Bettocchi, Carlo, additional, Busetto, Gian Maria, additional, Macarini, Luca, additional, Rocco, Bernardo, additional, Cormio, Luigi, additional, and Carrieri, Giuseppe, additional

Published
2022
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17. Oncological outcomes of whole-gland cryoablation in patients with prostate cancer and high risk of lymph node invasion.

Author

Selvaggio, Oscar, Falagario, Ugo, Finati, Marco, Bruno, Salvatore, Recchia, Marco, Milillo, Paola, Sanguedolce, Francesca, Silecchia, Giovanni, Macarini, Luca, Cormio, Luigi, and Carrieri, Giuseppe

Subjects
*CRYOSURGERY, *PROSTATE cancer patients, *LYMPH nodes, *DISEASE risk factors, *LYMPHADENECTOMY, *RADIONUCLIDE imaging
Abstract

Purpose: Prostate cryoablation has been proposed as an alternative to radical prostatectomy for men with localized prostate cancer (PCa); however, it is limited by the lack of data regarding oncological outcomes and the impossibility of performing a lymph node dissection. The aim of this study was to assess if whole-gland cryoablation is oncologically safe, especially for patients in whom pelvic lymph node dissection would be necessary. Materials and Methods: After institutional review board approval, we identified 102 patients who underwent whole-gland prostate cryoablation between 2013 and April 2019. Lymph node invasion (LNI) probability was computed using Briganti nomogram, and a 5% cutoff probability was used to stratify the population in two groups. Biochemical recurrence after procedure was assessed using Phoenix criteria. Multiparametric magnetic resonance imaging, (CT), and bone scan or choline positron-emission tomography/CT were performed for the detection of distant metastases. Results: Seventeen (17%) patients were treated for a low-risk PCa, 48 (47%) patients were at intermediate-risk PCa, and 37 (36%) patients were at high-risk PCa. Patients with a probability of LNI >5% (n = 46) exhibited higher prostate-specific antigen (PSA), PSA density, ISUP Grade Group, CT stage, and european association of urology (EAU) risk. Recurrence-free survival rates at 3 years' follow-up were 93%, 82%, and 72%, respectively for low-, intermediate-, and high-risk patients. At a median follow-up of 37 months (17–62), additional treatment and metastasis-free survival were 84% and 97%, respectively. No differences in oncological outcomes were found in patients with a probability of LNI above and below 5%. Conclusions: Prostate whole-gland cryoablation can be considered a safe procedure with acceptable outcomes in low- and intermediate-risk patients. A high preoperative risk of nodal involvement could not be considered an exclusion criterion to perform cryoablation. Further studies are required. [ABSTRACT FROM AUTHOR]

Published
2023
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18. MP46-14 INTRAOPERATIVE DIGITAL ANALYSIS OF ABLATION MARGINS (DAAM) BY FLUORESCENT CONFOCAL MICROSCOPY TO IMPROVE THE ACCURACY OF PARTIAL PROSTATE GLAND CRYOABLATION: A PILOT STUDY

Author

Falagario, Ugo, primary, Selvaggio, Oscar, additional, Bruno, Salvatore, additional, Recchia, Marco, additional, Sighinolfi, Maria Chiara, additional, Sanguedolce, Francesca, additional, Rastinehad, Ardeshir, additional, Sanchez-Salas, Rafael, additional, Barret, Eric, additional, Rocco, Bernardo, additional, Cormio, Luigi, additional, and Carrieri, Giuseppe, additional

Published
2021
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19. Intraoperative Digital Analysis of Ablation Margins (DAAM) by Fluorescent Confocal Microscopy to Improve Partial Prostate Gland Cryoablation Outcomes

Author

Selvaggio, Oscar, primary, Falagario, Ugo Giovanni, additional, Bruno, Salvatore Mariano, additional, Recchia, Marco, additional, Sighinolfi, Maria Chiara, additional, Sanguedolce, Francesca, additional, Milillo, Paola, additional, Macarini, Luca, additional, Rastinehad, Ardeshir R., additional, Sanchez-Salas, Rafael, additional, Barret, Eric, additional, Lugnani, Franco, additional, Rocco, Bernardo, additional, Cormio, Luigi, additional, and Carrieri, Giuseppe, additional

Published
2021
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20. PSA Density Help to Identify Patients With Elevated PSA Due to Prostate Cancer Rather Than Intraprostatic Inflammation: A Prospective Single Center Study

Author

Bruno, Salvatore M., primary, Falagario, Ugo G., additional, d’Altilia, Nicola, additional, Recchia, Marco, additional, Mancini, Vito, additional, Selvaggio, Oscar, additional, Sanguedolce, Francesca, additional, Del Giudice, Francesco, additional, Maggi, Martina, additional, Ferro, Matteo, additional, Porreca, Angelo, additional, Sciarra, Alessandro, additional, De Berardinis, Ettore, additional, Bettocchi, Carlo, additional, Busetto, Gian Maria, additional, Cormio, Luigi, additional, and Carrieri, Giuseppe, additional

Published
2021
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21. Prospective Validation of Pentraxin-3 as a Novel Serum Biomarker to Predict the Risk of Prostate Cancer in Patients Scheduled for Prostate Biopsy

Author

Falagario, Ugo Giovanni, primary, Busetto, Gian Maria, additional, Netti, Giuseppe Stefano, additional, Sanguedolce, Francesca, additional, Selvaggio, Oscar, additional, Infante, Barbara, additional, Ranieri, Elena, additional, Stallone, Giovanni, additional, Carrieri, Giuseppe, additional, and Cormio, Luigi, additional

Published
2021
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22. Does Multiparametric Magnetic Resonance of Prostate Outperform Risk Calculators in Predicting Prostate Cancer in Biopsy Naïve Patients?

Author

Falagario, Ugo Giovanni, primary, Silecchia, Giovanni, additional, Bruno, Salvatore Mariano, additional, Di Nauta, Michele, additional, Auciello, Mario, additional, Sanguedolce, Francesca, additional, Milillo, Paola, additional, Macarini, Luca, additional, Selvaggio, Oscar, additional, Carrieri, Giuseppe, additional, and Cormio, Luigi, additional

Published
2021
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28. Bioptic prostatic inflammation correlates with false positive rates of multiparametric magnetic resonance imaging in detecting clinically significant prostate cancer.

Author

Falagario, Ugo Giovanni, Recchia, Marco, Silecchia, Giovanni, Milillo, Paola, Francavilla, Alessia, Bruno, Salvatore Mariano, Selvaggio, Oscar, Busetto, Gian Maria, Sanguedolce, Francesca, Macarini, Luca, Carrieri, Giuseppe, and Cormio, Luigi

Subjects
PROSTATE, INFLAMMATION, MAGNETIC resonance imaging, PROSTATE cancer, BIOPSY
Abstract

Introduction The aim of this article was to determine the impact of bioptic prostatic inflammation (PI) on the false positive rate of multiparametric magnetic resonance imaging (mp-MRI) in detecting clinically significant prostate ancer (csPCa). Material and methods Our prostate biopsy database was queried to identify patients who underwent mp-MRI before PB at our institution. A dedicated uropathologist prospectively assessed bioptic PI using the Irani scores. We evaluated the association between mp-MRI findings, bioptic Gleason grade (GG) and aggressiveness of PI, and PCa detection. Results In total, 366 men were included. In patients with Prostate Imaging Reporting and Data System (PIRADS) 4-5 lesions, the csPCa (GG =2) rate was significantly higher in those with low-grade than in those with high-grade PI (36% vs 29.7%; p = 0.002), and in those with low-aggressive than in those with high-aggressive PI (37.7% vs 30.1%; p = 0.0003). The false positive rates of PIRADS 4-5 lesions for any PCa were 34.2% and 57.8% for low- and high-grade PI, respectively (p = 0.002); similarly, they were 29.5% and 59.4% for mildly and highly-aggressive PI (p = 0.0003). Potential study limitations include its retrospective analysis and single-center study and lack of assessment of the type of PI. Conclusions Bioptic PI directly correlates with false positive rates of mp-MRI in detecting csPCa. Clinicians should be aware that PI remains the most common pitfall of mp-MRI. [ABSTRACT FROM AUTHOR]

Published
2021
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33. Additional file 1: of Safety and efficacy of abiraterone acetate in chemotherapy-naive patients with metastatic castration-resistant prostate cancer: an Italian multicenter â real lifeâ study

Author

Cindolo, Luca, Natoli, Clara, Nunzio, Cosimo De, Tursi, Michele De, Valeriani, Maurizio, Giacinti, Silvana, Micali, Salvatore, Rizzo, Mino, Bianchi, Giampaolo, Martorana, Eugenio, Scarcia, Marcello, Ludovico, Giuseppe, Bove, Pierluigi, Laudisi, Anastasia, Selvaggio, Oscar, Carrieri, Giuseppe, Bada, Maida, Castellan, Pietro, Boccasile, Stefano, Ditonno, Pasquale, Chiodini, Paolo, Verze, Paolo, Mirone, Vincenzo, and Schips, Luigi

Abstract

Raw data abiraterone 2017. abiraterone database 2017. clinical data. (DOC 400 kb)

Published
2017
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35. Development and Internal Validation of Novel Nomograms Based on Benign Prostatic Obstruction-Related Parameters to Predict the Risk of Prostate Cancer at First Prostate Biopsy

Author

Cormio, Luigi, primary, Cindolo, Luca, additional, Troiano, Francesco, additional, Marchioni, Michele, additional, Di Fino, Giuseppe, additional, Mancini, Vito, additional, Falagario, Ugo, additional, Selvaggio, Oscar, additional, Sanguedolce, Francesca, additional, Fortunato, Francesca, additional, Schips, Luigi, additional, and Carrieri, Giuseppe, additional

Published
2018
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36. Safety and efficacy of abiraterone acetate in chemotherapy-naive patients with metastatic castration-resistant prostate cancer: an Italian multicenter “real life” study

Author

Cindolo, Luca, primary, Natoli, Clara, additional, De Nunzio, Cosimo, additional, De Tursi, Michele, additional, Valeriani, Maurizio, additional, Giacinti, Silvana, additional, Micali, Salvatore, additional, Rizzo, Mino, additional, Bianchi, Giampaolo, additional, Martorana, Eugenio, additional, Scarcia, Marcello, additional, Ludovico, Giuseppe Mario, additional, Bove, Pierluigi, additional, Laudisi, Anastasia, additional, Selvaggio, Oscar, additional, Carrieri, Giuseppe, additional, Bada, Maida, additional, Castellan, Pietro, additional, Boccasile, Stefano, additional, Ditonno, Pasquale, additional, Chiodini, Paolo, additional, Verze, Paolo, additional, Mirone, Vincenzo, additional, and Schips, Luigi, additional

Published
2017
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37. Pros-IT CNR: an Italian prostate cancer monitoring project

Author

Bassi, Pierfrancesco, Maggi, Ilaria Stefania, Artibani, Walter, Bassi, Pier Francesco, Bertoni, Filippo, Bracarda, Sergio, Conti, Giario Natale, Corvò, Renzo, Gacci, Mauro, Graziotti, Pierpaolo, Magrini, Stefano Maria, Maurizi Enrici, Riccardo, Mirone, Vincenzo, Montironi, Rodolfo, Muto, Giovanni, Pecoraro, Stefano, Porreca, Angelo, Ricardi, Umberto, Tubaro, Andrea, Zagonel, Vittorina, Zattoni, Filiberto, Crepaldi, Gaetano, Noale, Marianna, Alitto, Anna Rita, Ambrosi, Enrica, Antonelli, Alessandro, Aristei, Cynthia, Barbieri, Michele, Bardari, Franco, Bardoscia, Lilia, Barra, Salvina, Bartoncini, Sara, Basso, Umberto, Becherini, Carlotta, Bellavita, Rita, Bergamaschi, Franco, Berlingheri, Stefania, Berruti, Alfredo, Borghesi, Marco, Bortolus, Roberto, Borzillo, Valentina, Bosetti, Davide, Bove, Giuseppe, Bove, Pierluigi, Brausi, Maurizio, Bruni, Alessio, Baldari, Giorgio Bruno Cristiano, Brunocilla, Eugenio, Buffoli, Alberto, Buglione, Michela, Buttigliero, Consuelo, Cacciamani, Giovanni, Caldiroli, Michela, Cardo, Giuseppe, Carmignani, Giorgio, Carrieri, Giuseppe, Castelli, Emanuele, Castrezzati, Elisabetta, Catalano, Gianpiero, Cattarino, Susanna, Catucci, Francesco, Cavallini Francolini, Dario, Ceccarini, Ofelia, Celia, Antonio, Chiancone, Francesco, Chini, Tommaso, Cianci, Claudia, Cisternino, Antonio, Collura, Devi, Corbella, Franco, Corinti, Matteo, Corsi, Paolo, Cortese, Fiorenza, Corti, Luigi, de Nunzio, Cosimo, Cristiano, Olga, D'Angelillo, Rolando Maria, Da Pozzo, Luigi, D'Agostino, Daniele, D’Andrea, David, Dandrea, Matteo, De Angelis, Michele, De Cobelli, Ottavio, De Concilio, Bernardino, De Lisa, Antonello, De Luca, Stefano, De Stefani, Agostina, Deantoni, Chiara Lucrezia, Degli Esposti, Claudio, Destito, Anna, Detti, Beatrice, Di Muzio, Nadia, Di Stasio, Andrea, Di Stefano, Calogero, Di Trapani, Danilo, Difino, Giuseppe, Falivene, Sara, Farullo, Giuseppe, Fedelini, Paolo, Ferrari, Ilaria, Ferrau, Francesco, Ferro, Matteo, Fodor, Andrei, Fontana, Francesco, Francesca, Francesco, Giulio, Francolini, Frata, Paolo, Frezza, Giovanni, Gabriele, Pietro, Galeandro, Maria, Garibaldi, Ida Marina Elisabetta, Gennari, Pietro, Gentilucci, Alessandro, Giacobbe, Alessandro, Giussani, Laura, Giusti, Giuseppe, Gontero, Paolo, Guarneri, Alessia, Guida, Cesare, Gurioli, Alberto, Huqi, Dorijan, Imbimbo, Ciro, Ingrosso, Gianluca, Iotti, Cinzia, Italia, Corrado, La Mattina, Pierdaniele, Lamanna, Enza, Lastrucci, Luciana, Lazzari, Grazia, Liberale, Fabiola, Liguori, Giovanni, Lisi, Roberto, Lohr, Frank, Lombardo, Riccardo, Lovisolo, Jon, Ludovico, Giuseppe Mario, Macchione, Nicola, Maggio, Francesca, Malizia, Michele, Manasse, Gianluca, Mandoliti, Giovanni, Mantini, Giovanna, Marafioti, Luigi, Marciello, Luisa, Marconi, Alberto Mario, Martillotta, Antonietta, Marzano, Salvino, Masciullo, Stefano, Maso, Gloria, Massenzo, Adele, Mazzeo, Ercole, Mearini, Luigi, Medoro, Serena, Molè, Rosa, Monesi, Giorgio, Montanari, Emanuele, Montefiore, Franco, Montesi, Giampaolo, Morgia, Giuseppe, Moro, Gregorio, Muscas, Giorgio, Musio, Daniela, Muto, Paolo, Muzzonigro, Giovanni, Napodano, Giorgio, Negro, Carlo Luigi Augusto, Nidini, Mattia, Ntreta, Maria, Orsatti, Marco, Palazzolo, Carmela, Palumbo, Isabella, Parisi, Alessandro, Parma, Paolo, Pavan, Nicola, Pericolini, Martina, Pinto, Francesco, Pistone, Antonio, Pizzuti, Valerio, Platania, Angelo, Polli, Caterina, Pomara, Giorgio, Ponti, Elisabetta, Porcaro, Antonio Benito, Porpiglia, Francesco, Pugliese, Dario, Pycha, Armin, Raguso, Giuseppe, Rampini, Andrea, Randone, Donato Franco, Roscigno, Marco, Ruggieri, Maria Paola, Ruoppo, Giuseppe, Sanseverino, Roberto, Santacaterina, Anna, Santarsieri, Michele, Santoni, Riccardo, Scagliarini, Sarah, Scagliotti, Giorgio Vittorio, Scanzi, Mauro, Scarcia, Marcello, Schiavina, Riccardo, Sciarra, Alessandro, Sciorio, Carmine, Scolaro, Tindaro, Scuzzarella, Salvatore, Selvaggio, Oscar, Serao, Armando, Serni, Sergio, Signor, Marco Andrea, Silvani, Mauro, Silvano, Giovanni, Silvestris, Franco, Simeone, Claudio, Simone, Valeria, Spagnoletti, Girolamo, Spinelli, Matteo Giulio, Squillace, Luigi, Tombolini, Vincenzo, Toninelli, Mariastella, Triggiani, Luca, Trinchieri, Alberto, Trodella, Luca Eolo, Trodella, Lucio, Trombetta, Carlo, Tronnolone, Lidia, Tucci, Marcello, Urzì, Daniele, Valdagni, Riccardo, Valeriani, Maurizio, Vanoli, Maurizio, Vitali, Elisabetta, Zaramella, Stefano, Zeccolini, Guglielmo, Zini, Giampaolo, Noale, Marianna (ORCID:0000-0002-4313-8427), Maggi, Stefania, D’Angelillo, Rolando, D’agostino, Daniele, Mantini, Giovanna (ORCID:0000-0001-5303-4499), Bassi, Pierfrancesco, Maggi, Ilaria Stefania, Artibani, Walter, Bassi, Pier Francesco, Bertoni, Filippo, Bracarda, Sergio, Conti, Giario Natale, Corvò, Renzo, Gacci, Mauro, Graziotti, Pierpaolo, Magrini, Stefano Maria, Maurizi Enrici, Riccardo, Mirone, Vincenzo, Montironi, Rodolfo, Muto, Giovanni, Pecoraro, Stefano, Porreca, Angelo, Ricardi, Umberto, Tubaro, Andrea, Zagonel, Vittorina, Zattoni, Filiberto, Crepaldi, Gaetano, Noale, Marianna, Alitto, Anna Rita, Ambrosi, Enrica, Antonelli, Alessandro, Aristei, Cynthia, Barbieri, Michele, Bardari, Franco, Bardoscia, Lilia, Barra, Salvina, Bartoncini, Sara, Basso, Umberto, Becherini, Carlotta, Bellavita, Rita, Bergamaschi, Franco, Berlingheri, Stefania, Berruti, Alfredo, Borghesi, Marco, Bortolus, Roberto, Borzillo, Valentina, Bosetti, Davide, Bove, Giuseppe, Bove, Pierluigi, Brausi, Maurizio, Bruni, Alessio, Baldari, Giorgio Bruno Cristiano, Brunocilla, Eugenio, Buffoli, Alberto, Buglione, Michela, Buttigliero, Consuelo, Cacciamani, Giovanni, Caldiroli, Michela, Cardo, Giuseppe, Carmignani, Giorgio, Carrieri, Giuseppe, Castelli, Emanuele, Castrezzati, Elisabetta, Catalano, Gianpiero, Cattarino, Susanna, Catucci, Francesco, Cavallini Francolini, Dario, Ceccarini, Ofelia, Celia, Antonio, Chiancone, Francesco, Chini, Tommaso, Cianci, Claudia, Cisternino, Antonio, Collura, Devi, Corbella, Franco, Corinti, Matteo, Corsi, Paolo, Cortese, Fiorenza, Corti, Luigi, de Nunzio, Cosimo, Cristiano, Olga, D'Angelillo, Rolando Maria, Da Pozzo, Luigi, D'Agostino, Daniele, D’Andrea, David, Dandrea, Matteo, De Angelis, Michele, De Cobelli, Ottavio, De Concilio, Bernardino, De Lisa, Antonello, De Luca, Stefano, De Stefani, Agostina, Deantoni, Chiara Lucrezia, Degli Esposti, Claudio, Destito, Anna, Detti, Beatrice, Di Muzio, Nadia, Di Stasio, Andrea, Di Stefano, Calogero, Di Trapani, Danilo, Difino, Giuseppe, Falivene, Sara, Farullo, Giuseppe, Fedelini, Paolo, Ferrari, Ilaria, Ferrau, Francesco, Ferro, Matteo, Fodor, Andrei, Fontana, Francesco, Francesca, Francesco, Giulio, Francolini, Frata, Paolo, Frezza, Giovanni, Gabriele, Pietro, Galeandro, Maria, Garibaldi, Ida Marina Elisabetta, Gennari, Pietro, Gentilucci, Alessandro, Giacobbe, Alessandro, Giussani, Laura, Giusti, Giuseppe, Gontero, Paolo, Guarneri, Alessia, Guida, Cesare, Gurioli, Alberto, Huqi, Dorijan, Imbimbo, Ciro, Ingrosso, Gianluca, Iotti, Cinzia, Italia, Corrado, La Mattina, Pierdaniele, Lamanna, Enza, Lastrucci, Luciana, Lazzari, Grazia, Liberale, Fabiola, Liguori, Giovanni, Lisi, Roberto, Lohr, Frank, Lombardo, Riccardo, Lovisolo, Jon, Ludovico, Giuseppe Mario, Macchione, Nicola, Maggio, Francesca, Malizia, Michele, Manasse, Gianluca, Mandoliti, Giovanni, Mantini, Giovanna, Marafioti, Luigi, Marciello, Luisa, Marconi, Alberto Mario, Martillotta, Antonietta, Marzano, Salvino, Masciullo, Stefano, Maso, Gloria, Massenzo, Adele, Mazzeo, Ercole, Mearini, Luigi, Medoro, Serena, Molè, Rosa, Monesi, Giorgio, Montanari, Emanuele, Montefiore, Franco, Montesi, Giampaolo, Morgia, Giuseppe, Moro, Gregorio, Muscas, Giorgio, Musio, Daniela, Muto, Paolo, Muzzonigro, Giovanni, Napodano, Giorgio, Negro, Carlo Luigi Augusto, Nidini, Mattia, Ntreta, Maria, Orsatti, Marco, Palazzolo, Carmela, Palumbo, Isabella, Parisi, Alessandro, Parma, Paolo, Pavan, Nicola, Pericolini, Martina, Pinto, Francesco, Pistone, Antonio, Pizzuti, Valerio, Platania, Angelo, Polli, Caterina, Pomara, Giorgio, Ponti, Elisabetta, Porcaro, Antonio Benito, Porpiglia, Francesco, Pugliese, Dario, Pycha, Armin, Raguso, Giuseppe, Rampini, Andrea, Randone, Donato Franco, Roscigno, Marco, Ruggieri, Maria Paola, Ruoppo, Giuseppe, Sanseverino, Roberto, Santacaterina, Anna, Santarsieri, Michele, Santoni, Riccardo, Scagliarini, Sarah, Scagliotti, Giorgio Vittorio, Scanzi, Mauro, Scarcia, Marcello, Schiavina, Riccardo, Sciarra, Alessandro, Sciorio, Carmine, Scolaro, Tindaro, Scuzzarella, Salvatore, Selvaggio, Oscar, Serao, Armando, Serni, Sergio, Signor, Marco Andrea, Silvani, Mauro, Silvano, Giovanni, Silvestris, Franco, Simeone, Claudio, Simone, Valeria, Spagnoletti, Girolamo, Spinelli, Matteo Giulio, Squillace, Luigi, Tombolini, Vincenzo, Toninelli, Mariastella, Triggiani, Luca, Trinchieri, Alberto, Trodella, Luca Eolo, Trodella, Lucio, Trombetta, Carlo, Tronnolone, Lidia, Tucci, Marcello, Urzì, Daniele, Valdagni, Riccardo, Valeriani, Maurizio, Vanoli, Maurizio, Vitali, Elisabetta, Zaramella, Stefano, Zeccolini, Guglielmo, Zini, Giampaolo, Noale, Marianna (ORCID:0000-0002-4313-8427), Maggi, Stefania, D’Angelillo, Rolando, D’agostino, Daniele, and Mantini, Giovanna (ORCID:0000-0001-5303-4499)

Abstract

Aims: The Pros-IT CNR project aims to monitor a sample of Italian males ≥18 years of age who have been diagnosed in the participating centers with incident prostate cancer, by analyzing their clinical features, treatment protocols and outcome results in relation to quality of life. Methods: Pros-IT CNR is an observational, prospective, multicenter study. The National Research Council (CNR), Neuroscience Institute, Aging Branch (Padua) is the promoting center. Ninety-seven Italian centers located throughout Italy were involved. The field study began in September 1, 2014. Subjects eligible were diagnosed with biopsy-verified prostate cancer, naà ̄ve. A sample size of 1500 patients was contemplated. A baseline assessment including anamnestic data, clinical history, risk factors, the initial diagnosis, cancer staging information and quality of life (Italian UCLA Prostate Cancer Index; SF-12 Scale) was completed. Six months after the initial diagnosis, a second assessment evaluating the patient’s health status, the treatment carried out, and the quality of life will be made. A third assessment, evaluating the treatment follow-up and the quality of life, will be made 12 months after the initial diagnosis. The 4th, 5th, 6th and 7th assessments, similar to the third, will be completed 24, 36, 48 and 60 months after the initial diagnosis, respectively, and will include also a Food Frequency Questionnaire and the Physical Activity Scale for the Elderly. Discussion: The study will provide information on patients’ quality of life and its variations over time in relation to the treatments received for the prostate cancer.

Published
2017

39. Human Epidermal Growth Factor Receptor 2 in Non-Muscle Invasive Bladder Cancer: Issues in Assessment Methods and Its Role as Prognostic/Predictive Marker and Putative Therapeutic Target: A Comprehensive Review.

Author

Sanguedolce, Francesca, Russo, Davide, Mancini, Vito, Selvaggio, Oscar, Calò, Beppe, Carrieri, Giuseppe, and Cormio, Luigi

Subjects
EPIDERMAL growth factor receptors, BLADDER cancer, HUMAN growth, HORMONE receptor positive breast cancer, PROTHROMBIN, EPIDERMIS, PROGRESSION-free survival
Abstract

Although human epidermal growth factor receptor 2 (HER2) plays a prognostic and predictive role in breast and gastric cancer, its function in bladder cancer (BC) is still controversial. A comprehensive review of the literature has been carried out. An electronic search of databases from PubMed, Scopus, Google Scholar was implemented. The search terms were: "BC," "bladder carcinoma," "bladder neoplasm," "human epidermal growth factor 2," "HER2," "HER-2," "c-erbB-2," "c-erbB2," "erbB-2," "erbB2," "neu," "marker," "biomarker," and "prognosis". Results of the review consented to (a) summarize the available data on HER2 a predictor of recurrence and/or progression free survival on univariate and multivariate analysis, (b) explore the related issues in assessing HER2 status on these tumor samples, since they may severely impair its predictive function, and (c) report the state-of-the art of HER2 as a putative therapeutic target in BC and especially non-muscle invasive BC. HER2 stands out for being a prognostic factor as well as a therapeutic target in various cancers. Data from the literature concerning its use in BC provide conflicting results, probably due to the inherent complexity of BC biology. Efforts should be made to establish a suitable tumor-specific scoring system, and to assess single drugs' efficacy in well-designed clinical trials. [ABSTRACT FROM AUTHOR]

Published
2019
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40. Morphological and Immunohistochemical Biomarkers in Distinguishing Prostate Carcinoma and Urothelial Carcinoma: A Comprehensive Review.

Author

Sanguedolce, Francesca, Russo, Davide, Mancini, Vito, Selvaggio, Oscar, Calò, Beppe, Carrieri, Giuseppe, and Cormio, Luigi

Subjects
IMMUNOHISTOCHEMISTRY, MORPHOLOGY, PROSTATE cancer, TRANSITIONAL cell carcinoma, BIOMARKERS, CARCINOMA, DIFFERENTIAL diagnosis
Abstract

The differential diagnosis between high-grade prostate carcinoma and infiltrating urothelial carcinoma (UC) in transurethral resection prostate specimens as well as cystoprostatectomy specimens may often be challenging due to morphologic and clinical overlap of the 2 entities. Such distinction has critical therapeutic and staging consequences, yet it is hampered by both issues in morphology and by the low accuracy rates of single immunohistochemical markers, as reported in literature. This review aims to provide a comprehensive analysis of the available morphological and immunohistochemical parameters, which may allow to discriminate between prostate carcinoma and urothelial carcinoma in the proper clinical context and to discuss their diagnostic applications in daily practice. [ABSTRACT FROM AUTHOR]

Published
2019
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41. Prognostic and therapeutic role of HER2 expression in micropapillary carcinoma of the bladder.

Author

Sanguedolce, Francesca, Russo, Davide, Mancini, Vito, Selvaggio, Oscar, Calo, Beppe, Carrieri, Giuseppe, and Cormio, Luigi

Subjects
ESOPHAGEAL cancer, EPIDERMAL growth factor, BLADDER, BREAST cancer, CARCINOMA, HUMAN growth
Abstract

Micropapillary carcinoma of the bladder (MPBC) is a variant type of infiltrating urothelial carcinoma, which portends a poor biological behavior in terms of disease stage at first diagnosis and clinical outcome; its peculiar morphology raises issues concerning the ability of tumor detection by imaging techniques and proper biopsy procedure, and the appropriate treatment for non-muscle infiltrating and muscle-infiltrating MPBC remains a matter of debate. On the basis of its established prognostic and therapeutic role in breast and gastro-esophageal cancer in the first instance, the human epidermal growth factor receptor-2 (HER2) has been investigated in selected case series of MPBC over the last 10 years. The aim of the present review was to summarize the existing evidence on HER2 status in MPBC, and to discuss its present and future utility in risk assessment and treatment choice of this uncommon, yet aggressive, disease. [ABSTRACT FROM AUTHOR]

Published
2019

42. Prognostic Factors for Anastomotic Urinary Leakage Following Retropubic Radical Prostatectomy and Correlation With Voiding Outcomes

Author

Cormio, Luigi, primary, Di Fino, Giuseppe, additional, Scavone, Carmen, additional, Maroscia, Domenico, additional, Mancini, Vito, additional, Ruocco, Nicola, additional, Bellanti, Francesco, additional, Selvaggio, Oscar, additional, Sanguedolce, Francesca, additional, Lucarelli, Giuseppe, additional, and Carrieri, Giuseppe, additional

Published
2016
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45. Pentraxin 3: A Novel Biomarker for Predicting Progression from Prostatic Inflammation to Prostate Cancer

Author

Stallone, Giovanni, primary, Cormio, Luigi, additional, Netti, Giuseppe Stefano, additional, Infante, Barbara, additional, Selvaggio, Oscar, additional, Fino, Giuseppe Di, additional, Ranieri, Elena, additional, Bruno, Francesca, additional, Prattichizzo, Clelia, additional, Sanguedolce, Francesca, additional, Tortorella, Simona, additional, Bufo, Pantaleo, additional, Grandaliano, Giuseppe, additional, and Carrieri, Giuseppe, additional

Published
2014
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